CN107496567A - A kind of Chinese medicine preparation for treating diabetic foot and preparation method thereof - Google Patents
A kind of Chinese medicine preparation for treating diabetic foot and preparation method thereof Download PDFInfo
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- CN107496567A CN107496567A CN201710985660.3A CN201710985660A CN107496567A CN 107496567 A CN107496567 A CN 107496567A CN 201710985660 A CN201710985660 A CN 201710985660A CN 107496567 A CN107496567 A CN 107496567A
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
A kind of Chinese medicine preparation for treating diabetic foot, it is made up according to parts by weight of following raw material：8 12 parts of golden cypress, 26 parts of the coptis, 7 15 parts of radix scutellariae, 12 26 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 22 40,15 25 parts of stringy stonecrop, 27 34 parts of the Radix Astragali, 14 25 parts of oriental wormwood.It is an object of the invention to provide a kind of Chinese medicine preparation treated specifically for diabetic foot, and the Chinese medicine preparation treatment diabetes are with strong points, security is good, evident in efficacy, and small to patient body toxic side effect.
Description
Technical field
The invention belongs to medical product technical field, specifically a kind of Chinese medicine preparation for being used to treat diabetic foot
And preparation method thereof.
Background technology
Diabetes are one group of metabolic diseases characterized by hyperglycaemia, are that China's incidence of disease is high, endanger serious prevalence
One of disease.During diabetes, long-standing hyperglycaemia, cause various tissues, particularly eye, kidney, heart, blood vessel, nerve it is slow
Property infringement, dysfunction, trigger various diabetic complications.
Diabetes refer to diabetic foot because DPN makes lower limb defencive function decline, big blood vessel and micro- blood
Pipe lesion makes arterial perfusion deficiency cause microcirculation disorder and the morbid state of ulcer and gangrene occurs.Its incidence of disease be 15%~
20%, be common in that diabetes medical history is long, long-term blood glucose controls bad the elderly, be diabetes it is most commonly seen and serious and
Send out one of disease.The performance at initial stage of diabetes foot diseases is numb, send out cool, perceptibility reduces, easily injury, superficial wound is not easy to heal
Deng often easily ignored.Once wound, ulcer and infection occur in patient's foot or lower limb, such as treat not in time, be difficult often more
Close, a slight wound will not recover for a long time, wound scope rapid expansion, or even necrosis, amputation of finally having to, it is also possible to
It is lethal to induce infection.Great pain is caused to patient, also adds huge financial burden.
At present, treatment of the doctor trained in Western medicine for diabetes mainly controls blood glucose, blood fat and blood pressure, improves blood circulation and week
DPN is enclosed, uses antibiotic anti-infective therapy, the dressing processing to ulcer wound surface etc..It is conservative heteropathy, and west
Doctor's medication effect is limited, and function is single, and service life is grown, and generally requires lifelong medication.Chemicals can also be to body
Body produces intense stimulus, and toxic side effect is big, and easily bounce-back, security are poor, easy resistance, the financial burden for increasing patient.
With the development of the society, increasing people the sight for the treatment of disease invest in it is natural, have no toxic side effect
Chinese medicine class safe drugs.The traditional Chinese medical science thinks the diabetes category traditional Chinese medical science " gangrene of finger or toe " category, predominantly deficiency of both qi and yin, obstruction of collaterals by blood stasis, gas
Blood can not be caused by sensible four limbs.Therefore, in order to preferably treat diabetes, alleviate it is ailing, develop and develop it is a kind of it is natural in
Specific aim prepared by medicine and ageing strong, toxic side effect is small, security is good, evident in efficacy Chinese medicine composition are to diabetes
Recovery for it is actually necessary.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treated specifically for diabetic foot, the Chinese medicine preparation
Treatment diabetes are with strong points, security is good, evident in efficacy, and small to patient body toxic side effect.
The present invention realizes that the technical scheme that above-mentioned purpose uses is：A kind of Chinese medicine preparation for treating diabetic foot, according to
Parts by weight are made up of following raw material：Golden cypress 8-12 parts, coptis 2-6 parts, radix scutellariae 7-15 parts, capsule of weeping forsythia 22-40 Fen, Common St.Paulswort Herbs 12-
26 parts, stringy stonecrop 15-25 parts, Radix Astragali 27-34 parts, oriental wormwood 14-25 parts.
A kind of Chinese medicine preparation for treating diabetic foot, it is made up according to parts by weight of following raw material：10 parts of golden cypress, the coptis
5 parts, 10 parts of radix scutellariae, 20 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 30,20 parts of stringy stonecrop, 30 parts of the Radix Astragali, 20 parts of oriental wormwood.
A kind of Chinese medicine preparation for treating diabetic foot, it is made up according to parts by weight of following raw material：9 parts of golden cypress, the coptis 3
Part, 12 parts of radix scutellariae, 15 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 40,25 parts of stringy stonecrop, 27 parts of the Radix Astragali, 22 parts of oriental wormwood.
A kind of Chinese medicine preparation for treating diabetic foot, can be prepared as decoction, powder or capsule.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the decoction, comprises the following steps：
Step 1: according to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali are taken
It is put into oriental wormwood in boiling container, adds 500-1000 part water, normal pressure boils 20-40min, afterwards, filtered processing, filtered
Liquid a and filter residue a, it is standby；
Step 2: adding 300-500 part water into the filter residue a obtained by step 1, normal pressure boils 20-40min, afterwards, filtered
Processing, filtrate b and filter residue b is obtained, it is standby；
Step 3: filtrate b made from filtrate a made from step 1 and step 2 is uniformly mixed, traditional Chinese herbal decoction is produced.
In step 1, each raw material is smashed to the step of 200-300 mesh before adding boiling to boil, in addition to by each raw material, with
And each raw material after crushing is put into microwave dryer, 150-200 s microwave treatments are carried out under 600-900 W microwave powers
The step of.
In step 2, the filter residue a after adding the water, before being boiled, in addition to adds into the mixture of filter residue a and water
Enter carbohydrase and cellulase, the step of enzymolysis 2-3h is carried out under 45-55 DEG C of temperature conditionss.
In the enzymolysis step, the addition of carbohydrase and cellulase adds 10-20U carbohydrase for every gram of filter residue a；
15-25U cellulases.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the powder, comprises the following steps：According to described
The parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood are taken, is dried respectively
Afterwards, it is 100-200 mesh to be crushed to particle diameter, is well mixed, that is, obtains traditional Chinese powder medicine.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the capsule, comprises the following steps：According to described
The parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood are taken, is dried respectively
Afterwards, it is 100-200 mesh to be crushed to particle diameter, loads No. 1 capsule after being well mixed, that is, obtains Chinese medicinal capsule.
Beneficial effects of the present invention
1st, a kind of Chinese medicine preparation for treating diabetes provided by the invention, it is for diabetic foot pathogenesis based on the traditional Chinese medical science
Understanding, and the research to each taste herbal pharmacology function adjusts with reference to clinical experience for many years and repeatedly, and selects and come out
's.The unique selected eight tastes Chinese medicine of Chinese medicine preparation be raw material, scientific compatibility, is acted synergistically between various raw materials, mutual supplement with each other's advantages, Xiang get
Benefit is evident, fundamentally improves and effects a radical cure diabetes.Using the Radix Astragali of detoxicating and resolving a mass and the capsule of weeping forsythia as monarch drug in a prescription in formula, play attack mend it is simultaneous
Apply, invigorating qi for consolidating superficies, eliminating toxic are outgoing, clearing heat and detoxicating, desilting dissipating bind effect；Using golden cypress, the coptis, radix scutellariae, oriental wormwood and stringy stonecrop as
Ministerial drug, play a part of heat-clearing, clearing damp, removing toxic substances；Using Common St.Paulswort Herb as adjuvant thing, wind-dispelling, dehumidifying, heat-clearing, clearing and activating the channels and collaterals is played
And the effect of coordinating the drug actions of a prescription.Said medicine presses monarch compatibility, and each medicine synergy, finished product Chinese medicine preparation is with strong points,
Degree of absorption is good, and treatment cycle is short, and drug effect is notable, has promoting blood circulation and removing blood stasis, desilting dissipating bind, the curative effect such as anti-inflammation and sterilization, promoting the circulation of qi toxin expelling.
Red and swollen, the diminution surface of a wound can be quickly eliminated, is alleviated ailing.Chinese medicine preparation is integrally got rid of evils, and righting, formula are reasonable, and medication is gentle, can be from
Glycosuria pedopathy is fundamentally cured, recovers foot function.
2nd, a kind of Chinese medicine preparation for treating diabetes of the invention, using the conditioning to the whole health of patient as base
Plinth, with the interphase interaction of common conventional Chinese medicine component formula, coordinate at utmost play a role under synergy coordinates.Through facing
Bed research shows that Chinese medicine preparation of the invention is used to treat diabetes significant effect, local red and swollen heat pain disease after patient medication
Shape progressively disappears, and purulent secretion significantly reduces, and surface of a wound area constantly reduces, and after coordinating course for the treatment of medication treatment, cure rate is 75%
More than.Medicine effective percentage reaches 94%, the above, takes effect rapid.Meanwhile Chinese medicine preparation due to select raw material green natural, therefore,
Toxic side effect is small, and security reliability is good, even if long-term use of, also without obvious adverse reaction, and is not easy to rebound after being discontinued.
3rd, the Chinese medicine preparation for the treatment of diabetes of the invention is provided with to the original after crushing in the preparation process of decoction of medicinal ingredients
Expect the step of medicine carries out microwave treatment, by microwave treatment, material table layer can be made to burst, mechanism structure changes, possessed
Loose porous property, be advantageous to bulk drug powder it is follow-up boil and digest etc. in step more fully have therein
Pharmaceutical component activation is imitated, and is discharged, makes its function effect more notable.
4th, the present invention the step of filter residue after boiling, filtering is provided with enzymolysis processing, by enzymolysis processing, in solution
Carbohydrase and cellulase synergistic effect, the structures such as the cell membrane of bulk drug can be destroyed, made in eucaryotic cell structure
Effective pharmaceutical component is sufficiently discharged, and the polysaccharose substance in eucaryotic cell structure is hydrolyzed to the monose easily absorbed, with trip
Amorph is discharged into filtrate, so as to improve the extraction of bulk drug and effective rate of utilization and effective pharmaceutical component by the suction of human body
Receive.
Embodiment
A kind of Chinese medicine preparation for treating diabetic foot, it is made up according to parts by weight of following raw material：Golden cypress 8-12 parts, Huang
Even 2-6 parts, radix scutellariae 7-15 parts, capsule of weeping forsythia 22-40 Fen, Common St.Paulswort Herb 12-26 parts, stringy stonecrop 15-25 parts, Radix Astragali 27-34 parts, oriental wormwood
14-25 parts.
Preferably, the Chinese medicine preparation of described treatment diabetic foot, is made up according to parts by weight of following raw material：Golden cypress
10 parts, 5 parts of the coptis, 10 parts of radix scutellariae, 20 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 30,20 parts of stringy stonecrop, 30 parts of the Radix Astragali, 20 parts of oriental wormwood.
Preferably, the Chinese medicine preparation of described treatment diabetic foot, is made up according to parts by weight of following raw material：Golden cypress
9 parts, 3 parts of the coptis, 12 parts of radix scutellariae, 15 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 40,25 parts of stringy stonecrop, 27 parts of the Radix Astragali, 22 parts of oriental wormwood.
A kind of Chinese medicine preparation for treating diabetic foot, can be prepared as decoction, powder or capsule.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the decoction, comprises the following steps：
Step 1: according to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali are taken
It is put into oriental wormwood in boiling container, adds 500-1000 part water, normal pressure boils 20-40min, afterwards, filtered processing, filtered
Liquid a and filter residue a, it is standby；
Step 2: adding 300-500 part water into the filter residue a obtained by step 1, normal pressure boils 20-40min, afterwards, filtered
Processing, filtrate b and filter residue b is obtained, it is standby；
Step 3: filtrate b made from filtrate a made from step 1 and step 2 is uniformly mixed, traditional Chinese herbal decoction is produced.
In step 1, each raw material is smashed to the step of 200-300 mesh before adding boiling to boil, in addition to by each raw material, with
And each raw material after crushing is put into microwave dryer, 150-200 s microwave treatments are carried out under 600-900 W microwave powers
The step of.
In step 2, the filter residue a after adding the water, before being boiled, in addition to adds into the mixture of filter residue a and water
Enter carbohydrase and cellulase, the step of enzymolysis 2-3h is carried out under 45-55 DEG C of temperature conditionss.
In the enzymolysis step, the addition of carbohydrase and cellulase adds 10-20U carbohydrase for every gram of filter residue a；
15-25U cellulases.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the powder, comprises the following steps：According to described
The parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood are taken, is dried respectively
Afterwards, it is 100-200 mesh to be crushed to particle diameter, is well mixed, that is, obtains traditional Chinese powder medicine.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the capsule, comprises the following steps：According to described
The parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood are taken, is dried respectively
Afterwards, it is 100-200 mesh to be crushed to particle diameter, loads No. 1 capsule after being well mixed, that is, obtains Chinese medicinal capsule.
Using the Radix Astragali and the capsule of weeping forsythia as monarch drug in a prescription in the formula of the Chinese medicine preparation of the present invention, with golden cypress, the coptis, radix scutellariae, oriental wormwood and hang down
Basin grass be ministerial drug , using Common St.Paulswort Herb as adjuvant thing, monarch synergy, play radical cure diabetic foot good efficacy.
Wherein, the Radix Astragali, property is sweet, tepor.Return lung, spleen, liver and kidney channel.With invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, sore life
The effect of flesh, inducing diuresis for removing edema, it is remarkably improved immunity of organisms.
The capsule of weeping forsythia, cool in nature, bitter, enter the heart, liver, gallbladder channel.With clearing heat and detoxicating, the effect of mass dissipating and swelling eliminating, desilting dissipating bind.
Golden cypress, bitter, it is cold in nature.Return kidney channel, bladder, large intestine channel.With purging intense heat eliminating dampness, clearing heat and detoxicating, row's sore analgesic, antibacterial
The function of anti-inflammatory.
The coptis, it is bitter, cold in nature.The thoughts of returning home, spleen, stomach, liver, courage, large intestine channel.Sore, heat-clearing and damp-drying drug, inducing diaphoresis purging intense heat are controlled with removing toxic substances
The effect of.Also there is significant anti-inflammatory, detoxication.
Radix scutellariae, it is bitter, cold in nature.Return lung, courage, spleen, large intestine, small intestinl channel.With heat-clearing and damp-drying drug, purging intense heat and detonicating, stop blooding, decompression
Effect.
Oriental wormwood, bitter, property are pungent, are slightly cold.Returns spleen, stomach, liver, gallbladder channel.With clearing heat and promoting diuresis, removing jaundice defaecation, diuresis is antipyretic, protects
Liver cholagogic, removing toxic substances is antibacterial, improves the effect of blood flow microcirculation.
Stringy stonecrop, it is sweet, cool in nature.There is the effect of removing dampness through diuresis and removing jaundice, clearing heat and detoxicating.
Common St.Paulswort Herb, there is dispelling cold and dehumidification, clearing heat and detoxicating, clearing and activating the channels and collaterals, antibacterial and Antimalarial.
Eight taste Chinese medicine green naturals in selection, therefore, toxic side effect is small, and cost is low, and cure rate is high, and drug action is strong,
Pollution-free in production, security reliability is good, even if long-term use of, also the adverse reactions such as dependence will not be produced to medicine, after drug withdrawal
It is not easy to rebound.The preparation method of medicine is simple and easy to control, and cost is low, is worthy to be popularized.
Embodiment 1：
The Chinese medicine preparation of the treatment diabetic foot of the present embodiment, is made up according to parts by weight of following raw material：10 parts of golden cypress, Huang
5 parts of company, 10 parts of radix scutellariae, 20 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 30,20 parts of stringy stonecrop, 30 parts of the Radix Astragali, 20 parts of oriental wormwood.
A kind of preparation method for the Chinese medicine preparation decoction for treating diabetic foot, comprises the following steps：
Step 1: according to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali are taken
And oriental wormwood, each raw material is smashed to 200 mesh, afterwards, is put into microwave dryer, it is micro- to carry out 200 s under 600 W microwave powers
Ripple processing, then in boiling container, 500 parts of water of addition, normal pressure boils 30min, afterwards, filtered processing, filtered transposition
Liquid a and filter residue a, it is standby；
Step 2: add 400 parts of water into the filter residue a obtained by step 1, afterwards, according to every gram of filter residue a add 15U carbohydrase and
The ratio of 20U cellulases, carbohydrase and cellulase are added into the mixture of filter residue a and water, under 50 DEG C of temperature conditionss
Enzymolysis 3h is carried out, afterwards, normal pressure boils 40min, filtered processing, obtains filtrate b and filter residue b, standby；
Step 3: filtrate b made from filtrate a made from step 1 and step 2 is uniformly mixed, traditional Chinese herbal decoction is produced.
Embodiment 2：
The Chinese medicine preparation of the treatment diabetic foot of the present embodiment, is made up according to parts by weight of following raw material：9 parts of golden cypress, Huang
3 parts of company, 12 parts of radix scutellariae, 15 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 40,25 parts of stringy stonecrop, 27 parts of the Radix Astragali, 22 parts of oriental wormwood.
A kind of preparation method for the Chinese medicine preparation powder for treating diabetic foot, comprises the following steps：According to each original
The parts by weight of material, take golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood, after being dried respectively, powder
It is 100-200 mesh to be broken to particle diameter, is well mixed, that is, obtains traditional Chinese powder medicine.
Embodiment 3：
The Chinese medicine preparation of the treatment diabetic foot of the present embodiment, is made up according to parts by weight of following raw material：8 parts of golden cypress, Huang
6 parts of company, 15 parts of radix scutellariae, 12 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 22,15 parts of stringy stonecrop, 34 parts of the Radix Astragali, 14 parts of oriental wormwood.
A kind of Chinese medicine preparation for treating diabetic foot, the preparation method of the capsule, comprises the following steps：According to described
The parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali and oriental wormwood are taken, is dried respectively
Afterwards, it is 100-200 mesh to be crushed to particle diameter, loads No. 1 capsule after being well mixed, that is, obtains Chinese medicinal capsule.
Embodiment 4：
The Chinese medicine preparation of the treatment diabetic foot of the present embodiment, is made up according to parts by weight of following raw material：12 parts of golden cypress, Huang
2 parts of company, 7 parts of radix scutellariae, 26 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 40,20 parts of stringy stonecrop, 30 parts of the Radix Astragali, 25 parts of oriental wormwood.
A kind of preparation method for the Chinese medicine preparation decoction for treating diabetic foot, comprises the following steps：
Step 1: according to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali are taken
And oriental wormwood, each raw material is smashed to 300 mesh, afterwards, is put into microwave dryer, it is micro- that 150s is carried out under 900 W microwave powers
Ripple processing, then in boiling container, 1000 parts of water of addition, normal pressure boils 40min, afterwards, filtered processing, filtered transposition
Liquid a and filter residue a, it is standby；
Step 2: add 500 parts of water into the filter residue a obtained by step 1, afterwards, according to every gram of filter residue a add 20U carbohydrase and
The ratio of 15U cellulases, carbohydrase and cellulase are added into the mixture of filter residue a and water, under 55 DEG C of temperature conditionss
Enzymolysis 2h is carried out, afterwards, normal pressure boils 40min, filtered processing, obtains filtrate b and filter residue b, standby；
Step 3: filtrate b made from filtrate a made from step 1 and step 2 is uniformly mixed, traditional Chinese herbal decoction is produced.
Clinical test
The effect of in order to preferably verify Chinese medicine preparation of the present invention, controlled using made from the raw material proportioning described in the embodiment of the present invention
The Chinese medicine preparation for treating diabetic foot carries out clinical observation research, to further illustrate treatment of the present invention to treatment diabetic foot
Effect.
Clinical data：
1st, experimental subjects：It is the patient totally 150 of diabetic foot after diagnosing；Age distribution is between 18-80 year；
2nd, treatment method：Take Chinese medicine preparation decoction or capsule used in the present invention；The instructions of taking of decoction is that early daily, evening is respectively
Orally once, each taking 200-250mL, 30 days are a course for the treatment of；The instructions of taking of capsule is, each taking 63 times a day,
Warm water is taken after mixing it with water, 30 days are a course for the treatment of.
3rd, evaluation criterion is treated：
1., it is effective：Local red and swollen heat pain symptom disappears, and purulent secretion significantly reduces, and surface of a wound area reduces more than 50%.
2., effectively：Local red and swollen heat pain symptom mitigation, purulent secretion are reduced, and surface of a wound area reduces less than 50%.
3., it is invalid：The surface of a wound and its surrounding have no obvious change.
4th, therapeutic effect：150 patients that the present invention is treated, wherein effective 114, effective 28, invalid 8, control
Effective percentage is treated up to 94.6%, obvious effective rate is up to 76%.As a result show, Chinese medicine preparation reasonable recipe of the present invention, to treating diabetes
Disease is evident in efficacy.
5th, clinical treatment model case：
Medical record example 1
Wu so-and-so, man, 79 years old, Ruzhou City enrich people two people from street, suffer from diabetes 7 years, right foot festers 4 months.Right foot is red and swollen, local skin
Wen Gao, second and third toe lack such as, and stump exposure, obscure boundary is clear, has a large amount of purulent materials to ooze out；Visible 7 × the 4cm of foot bottom, 5
× 3cm exanthemv mouth, sharpness of border, it is seen that tendon exposes, and has a small amount of purulent material to ooze out；On the inside of instep, hallux toe root
Respectively see an exanthemv, obscure boundary is clear, has a small amount of purulent material to ooze out.Double lower limb epidermatic atrophy, fine hair on birds or animals hair come off, bilateral instep
Arteriopalmus weakens, and double lower limb ankle jerk is normal, and the acupuncture pain sensation, seismesthesia, pressure are felt, temperature sensation slightly lowers.It is diagnosed as sugar
Urinate 4 grades of foot disease disease.Blood glucose fluctuation is controlled with OHA, coordinates local conventional debridement, physiological saline soak, conventional anti-sense
Dye.The Chinese medicinal capsule of the treatment diabetic foot of the present invention is taken, capsule size is No. 1, each taking 63 times a day, warm water punching
Clothes, continuous treatment 1 month, purulent secretion significantly reduces, granulation tissue raised growth, and the surface of a wound reduces 62%.
Medical record example 2
What so-and-so, female, 61 years old, Ruzhou City Jiao villages and small towns section people from village, suffer from diabetes 3 years, right sufficient red and swollen heat pain 20 days, You Zu Hallux toes are burst
Rotten 10 days, right sufficient intermediate edema, right sufficient thumb top skin blacked, atrophy, the visible one 3 × 6cm ulcer surfaces in inner side, had a large amount of bad
Dead tissue retains, and volatilizes stench.Diabetic foot is diagnosed as 4 grades.With insulin and OHA control blood glucose fluctuation, match somebody with somebody
Close local conventional debridement, physiological saline soak, conventional anti-infection.The traditional Chinese herbal decoction of the treatment diabetic foot of the present invention is taken,
Each taking 250 milliliters, 2 times a day warmly taking, continuous treatment 2 months, purulent secretion significantly reduces, and foot red and swollen heat pain disappears, and 2
Individual month ulcer surface reduces 57%, foot ulcers healing in 4 months.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not limitation with the present invention, all in essence of the invention
God and all any modification, equivalent and improvement made within principle, should be included in the scope of the protection.
Claims (10)
1. a kind of Chinese medicine preparation for treating diabetic foot, it is characterised in that be made up according to parts by weight of following raw material：Golden cypress
8-12 parts, coptis 2-6 parts, radix scutellariae 7-15 parts, capsule of weeping forsythia 22-40 Fen, Common St.Paulswort Herb 12-26 parts, stringy stonecrop 15-25 parts, Radix Astragali 27-34
Part, oriental wormwood 14-25 parts.
A kind of 2. Chinese medicine preparation for treating diabetic foot as claimed in claim 1, it is characterised in that according to parts by weight by
Following raw material is made：10 parts of golden cypress, 5 parts of the coptis, 10 parts of radix scutellariae, 20 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 30,20 parts of stringy stonecrop, the Radix Astragali 30
Part, 20 parts of oriental wormwood.
A kind of 3. Chinese medicine preparation for treating diabetic foot as claimed in claim 1, it is characterised in that according to parts by weight by
Following raw material is made：9 parts of golden cypress, 3 parts of the coptis, 12 parts of radix scutellariae, 15 parts of the Fen, Common St.Paulswort Herbs of the capsule of weeping forsythia 40,25 parts of stringy stonecrop, the Radix Astragali 27
Part, 22 parts of oriental wormwood.
4. a kind of Chinese medicine preparation for treating diabetic foot as described in any claim in claim 1-3, its feature exist
In：Decoction, powder or capsule can be prepared as.
A kind of 5. Chinese medicine preparation for treating diabetic foot as claimed in claim 4, it is characterised in that the preparation of the decoction
Method, comprise the following steps：
Step 1: according to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, stringy stonecrop, the Radix Astragali are taken
It is put into oriental wormwood in boiling container, adds 500-1000 part water, normal pressure boils 20-40min, afterwards, filtered processing, filtered
Liquid a and filter residue a, it is standby；
Step 2: adding 300-500 part water into the filter residue a obtained by step 1, normal pressure boils 20-40min, afterwards, filtered
Processing, filtrate b and filter residue b is obtained, it is standby；
Step 3: filtrate b made from filtrate a made from step 1 and step 2 is uniformly mixed, traditional Chinese herbal decoction is produced.
A kind of 6. Chinese medicine preparation for treating diabetic foot as claimed in claim 5, it is characterised in that：In step 1, respectively
Raw material is smashed to the step of 200-300 mesh before adding boiling to boil, in addition to by each raw material, and each raw material after crushing is put into
In microwave dryer, under 600-900 W microwave powers the step of progress 150-200 s microwave treatments.
A kind of 7. Chinese medicine preparation for treating diabetic foot as claimed in claim 5, it is characterised in that：In step 2, institute
State filter residue a after adding the water, before being boiled, in addition to carbohydrase and cellulase are added into the mixture of filter residue a and water, in
The step of enzymolysis 2-3h is carried out under 45-55 DEG C of temperature conditionss.
A kind of 8. Chinese medicine preparation for treating diabetic foot as claimed in claim 7, it is characterised in that：The enzymolysis step
In, the addition of carbohydrase and cellulase adds 10-20U carbohydrase for every gram of filter residue a；15-25U cellulases.
A kind of 9. Chinese medicine preparation for treating diabetic foot as claimed in claim 4, it is characterised in that the preparation of the powder
Method, comprise the following steps：According to the parts by weight of each raw material, golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, vertical basin are taken
Grass, the Radix Astragali and oriental wormwood, after being dried respectively, it is 100-200 mesh to be crushed to particle diameter, is well mixed, that is, obtains traditional Chinese powder medicine.
A kind of 10. Chinese medicine preparation for treating diabetic foot as claimed in claim 4, it is characterised in that the system of the capsule
Preparation Method, comprise the following steps：According to the parts by weight of each raw material, take golden cypress, the coptis, radix scutellariae, capsule of weeping forsythia, Common St.Paulswort Herbs, hang down
Basin grass, the Radix Astragali and oriental wormwood, after being dried respectively, it is 100-200 mesh to be crushed to particle diameter, loads No. 1 capsule after being well mixed, i.e.,
Obtain Chinese medicinal capsule.
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| CN108815248A (en) * | 2018-09-13 | 2018-11-16 | 姜彩辉 | A kind of Traditional Chinese medicinal spray that treating diabetes and preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108815248A (en) * | 2018-09-13 | 2018-11-16 | 姜彩辉 | A kind of Traditional Chinese medicinal spray that treating diabetes and preparation method |
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