CN108261368A - A kind of compound goes pouch gel and its preparation process - Google Patents
A kind of compound goes pouch gel and its preparation process Download PDFInfo
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- CN108261368A CN108261368A CN201810131866.4A CN201810131866A CN108261368A CN 108261368 A CN108261368 A CN 108261368A CN 201810131866 A CN201810131866 A CN 201810131866A CN 108261368 A CN108261368 A CN 108261368A
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- Prior art keywords
- pouch
- gel
- deionized water
- skin
- preparation process
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses a kind of compounds to remove pouch gel and its preparation process, raw material includes carbomer, butanediol, propylene glycol, LUJ20, eye and encloses agent, caffeine silanol, heparin sodium, asiaticosid, safranine flower extract, horse chestnut extract, 1,2 hexylene glycols, rose, triethanolamine, parahydroxyacet-ophenone, L carnitines, Sodium Hyaluronate, D panthenols；Eye circumference edema, fat accumulation, degradation fat can be alleviated, alleviate pouch fat, pouch and pigmentation caused by elastic fibers of skin relaxation；The effect of improving the degree of compacting of eye part skin, grease promoted to decompose, reaches Firm；With collagenous fibres are inhibited, inhibit proliferation of fibrous tissue, and with antioxidation and consumer edema effect, increase the finish and flexibility of skin, commonly use the remarkable efficacy can with the aging of delaying skin, with anti-aging.
Description
Technical field
The present invention relates to gels, and in particular to a kind of to remove pouch gel and preparation method thereof containing compound plant ingredient.
Background technology
More and more with the night life of urbanite, the time stayed up late is increasingly longer, with also permanent, the disease of eye between at the moment
Sick and unsound symptom is also more and more, and pouch is also just a large amount of therewith to be occurred.Most prominent symptom is ocular edema, eye skin
Tissue elasticity constantly declines, and integumentary musculature tissue is constantly sagging.Meanwhile with human senescence process, the skin of eye constantly becomes
It is thin, it follows the string, senile cutaneous lesions occurs, and be more prone to be stimulated.Usual eye skin aging always companion
With the appearance of drying, water shortage and eye disease.
To solve the above-mentioned problems, a large amount of significant exploration work have been done in industry, have emerged large quantities of eyes in the market
Portion's product is mainly used for preventing eye skin aging, delays drying, but these stoste generally use synthetics are more,
Skin of face is easily enabled to generate irritation, so as to cause skin allergy and red and swollen phenomenon, and then skin is made to become more fragile quick
Sense.
Invention content
The present invention in view of the drawbacks of the prior art, provides one kind and avoids bringing human body eye part skin irritation, eliminates eye
The pouch in portion, eye wrinkle, livid ring around eye enable eye and surrounding skin keep young, penetrating pale；Skin sense is soft and smooth and high resilience,
Meet the product for removing pouch demand simultaneously.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：A kind of compound removes pouch gel, including following
Component (by weight),
The present invention also provides the preparation processes that a kind of compound removes pouch gel, include the following steps：
Step 1) carries out the deionized water of predetermined weight to be warming up to 90-100 DEG C, and keep the temperature 30 minutes；Cool down deionization
Water extremely, at 40-60 DEG C, respectively by raw material：Eye encloses agent, caffeine silanol, heparin sodium, asiaticosid, safflower extraction
In object, horse chestnut extract, l-carnitine input agitated kettle A, stir evenly for use；
Step 2) by the deionized water of the raw material after cleaning and predetermined amount respectively successively put into extractor in, carry out respectively from
Heart processing, filtering obtain pre-mixing liquor；
Step 3) is by deionized water and carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, Sodium Hyaluronate, rose
Rare hydrosol puts into agitated kettle B and stirs successively, and carbomer, Sodium Hyaluronate uniform dissolution is made in deionized water, and to heat
To 80-100 DEG C, and keep the temperature 30 minutes；
The mixed liquor of step 3) is cooled to 50-70 DEG C by step 4) under stirring；
Step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, is then cooled to
At 40-50 DEG C, be separately added into parahydroxyacet-ophenone, 1,2- hexylene glycols, triethanolamine, and make the pH value of mixture for 5.3~
6.5, and the viscosity of mixture be 15000~20000mpa.s when to get finished product.
Preferably, step 1) deionized water carries out being warming up to 95 DEG C, is subsequently cooled to add in raw material at 50 DEG C.
Preferably, step 3) is by deionized water and carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, hyalomitome
Sour sodium, rose put into agitated kettle B and stir successively, make carbomer, Sodium Hyaluronate uniform dissolution in deionized water,
And 90 DEG C are heated to, and keep the temperature 30 minutes.
Preferably, in step 3), the ratio of deionized water and LUJ20 are 20：1.
Preferably, the mixed liquor of step 3) is cooled to 60 DEG C by step 4) under stirring, and speed of agitator is 30~50
Rev/min.
Preferably, step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, then
When being cooled to 45 DEG C, it is separately added into parahydroxyacet-ophenone, 1,2- hexylene glycols, triethanolamine.
A kind of compound of the present invention removes pouch gel, and agent, caffeine silanol C, heparin sodium, centella are enclosed using eye
Glycosides, safranine flower extract and horse chestnut extract etc. are used as component, are mutually mixed, can alleviate eye circumference edema, fat accumulation, degradation
Fat alleviates pouch fat, pouch and pigmentation caused by elastic fibers of skin relaxation；Improve compacting for eye part skin
The effect of degree promotes grease to decompose, reaches Firm；With collagenous fibres are inhibited, inhibit proliferation of fibrous tissue, and with anti-oxidant
Effect and consumer edema effect increase the finish and flexibility of skin, and anti-aging can be had with the aging of delaying skin by commonly using
Remarkable efficacy.
Description of the drawings
Fig. 1 is the flow chart for the preparation process that a kind of compound of the present invention removes pouch gel.
Fig. 2 is the preparation process figure that a kind of compound of the present invention removes pouch gel.
Specific embodiment
The present invention provides a kind of compounds to remove pouch gel, including following components (by weight)：
Wherein, eye enclose agent, can alleviate eye circumference edema, fat accumulation, elastic fibers of skin relaxation caused by pouch
And pigmentation.The effect of caffeine silanol C improves the degree of compacting of eye part skin, grease is promoted to decompose, reaches Firm.Liver
Plain sodium has anticoagulant effect.Asiaticosid has and inhibits collagenous fibres, inhibits proliferation of fibrous tissue, work promoting blood circulation and removing blood stasis
With.Safranine flower extract has the remarkable efficacy of anti-aging, improves the degree of compacting of eye part skin.Horse chestnut extract, it is anti-oxidant
Effect and consumer edema effect, play moisture-keeping function, increase the finish and flexibility of skin, commonly using can be with the aging of delaying skin.
L-cn promotes adipose conversion to have the function of degradation fat into energy, can alleviate pouch fat.
First, eye encloses agent
Eye encloses agent, (rich in phytosterol, can promote blood circulation containing 5 Plant Extracts, anti-inflammatory, promote glue
Former albumen generation), 3 kinds are conducive to silanol and the two kinds of whitening agent synergistic effects that connective tissue is rebuild, and can be directed to eye circumference edema, fat
Pouch and pigmentation caused by fat is accumulated and the elastomer of skin relaxes.For various eye products.
2nd, caffeine silanol C
Caffeine silanol C (Cafeisilane C), purposes：Anti-cellulite knits scorching, solution fat, body compacts, removes pouch；Silicon
Alkanol and caffeine synergistic effect, there is prominent solution fat function.Solution fat promotes cyclic annular adenosine phosphoric acid activation by element silicon, leads to
Cross the formation and accumulation that triglycerides is reduced to the inhibiting effect of lipoprotein lipase.Skin histology is rebuild simultaneously, reaches Firm, anti-inflammatory
And other effects.Suitable for weight reducing, body and skin of face consolidation remove the products such as pouch.
3rd, heparin sodium
Heparin sodium (Heparin sodium), can interfere many links of blood clotting process, there is anticoagulation work in vivo and in vitro
With.Its mechanism of action is more complicated, mainly by being combined with antithrombin Ⅲ (AT- III), and enhance the latter to the II of activation,
Ⅸth, the inhibiting effect of the coagulation factor of X, Ⅺ and Ⅻ, consequence are related to preventing platelet aggregation and destroy, interfere factor Ⅹ
It is formed, factor is prevented to become fibrin ferment, inhibit fibrin ferment, so as to which fibrinogen be interfered to become fibroblast cells, so as to send out
Wave anticoagulation.
4th, asiaticosid
Asiaticosid, also known as Asiaticoside, faint yellow to fallow powder；Odorless, bitter is slightly moist with drawing.
There is promotion Wound Healing.For treating wound, operation wound, burn, keloid and chorionitis.It is clearing heat and detoxicating, dampness removing
Detumescence.The long-lived medicine of Asians, can beneficial brain refresh oneself.Research shows that with nourishing, anti-inflammatory, healing of wound, diuresis defaecation and town
It is set for using.It is also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate deep skin
The replacement of cell.It is neural nourishing agent, can improve memory, mitigates mental fatigue；It can also blood pressure lowering, treatment hepatopathy etc..
Pharmacological action：Inhibit proliferation of fibrous tissue.Asiaticosid can inhibit collagenous fibres, have and inhibit proliferation of fibrous tissue
Effect.Promote skin growth.Rabbit intramuscular injection can promote skin growth, local leukocytosis, and connective tissue rete vasculosum increases, and stick
Liquid secretion increases, and fur hyperplasia accelerates, and plays the role of inhibiting skin ulcer.The stable effect of calmness.Wherein, contained glucoside is to small
Mouse, rat have calm, stable effect, this effect is mainly the influence of the cholinergic system in Central nervous system.Alcohol extracting
Object is without analgesic activity.
Effect to skin histology.Asiaticoside can treat skin ulcer, such as obstinate sexual trauma, cutaneous tuberculosis, leprosy.
Mouse, cavy, rabbit muscle, which are injected or be subcutaneously implanted, can promote skin growth, local leukocytosis, connective tissue rete vasculosum
Hyperplasia, mucous secretion increase, hair and tail Acceleration of growth etc..Once there is report with the alcohol extracting things of 0.25-1% containing centella (containing product
Avenge oxalic acid, Asiaticoside) creams agent (wherein still containing embryo's or calf, pig or sheepskin skin, the water alcohol extracting of liver, brain
Object) treatment skin disease, obtains good result.Clearing heat and promoting diuresis.Abscess of throat is treated, aphthae, headache, body is warm, thirsty etc..
It is promoting blood circulation and removing blood stasis.For treating swelling and pain by traumatic injury, worm snake bite, redness and swelling of joints etc..
Antibacterial anti-inflammatory.Treatment herpes zoster, dysentery caused by virus or bacterium；Jaundice with damp-heat pathogen；Oedema；Stranguria.
Available for erysipelas；Scrofula；Close pyogenic infections from tumour or sore.
Li Shui and spleen.Treat the watery diarrhea caused by damp and hot, dysentery, be additionally operable to gasteremphraxis stomachache, stomach Qi not under, indigestion,
Gasteremphraxis is had the hiccups, children's infantile malnutrition symptom.
5th, safranine flower extract
Safranine flower extract, containing a variety of carotene compounds, content about 2%, wherein, detach to obtain crocin
(crocin) -1, crocin -2, crocin -3, crocin -4, trans- and cis- safron dimethyl ester (trans-,
Cis-crocetin dimethyl ester), α-, beta carotene, α-bayer acid (α-crocetin), zeaxanthin, kind
Lycopene, picrocrocin (picrocrocin) are main in oily separately containing Crocin, bitter principle and volatile oil 0.4%~1.3%
It is the decomposition product of picrocrocin containing safranal (safranal), secondly containing eucalyptol, firpene etc., there is anti-aging
Remarkable efficacy improves the degree of compacting of eye part skin.
6th, horse chestnut extract
The seed and bark of horse chestnut, qi-regulating is done in China and Chinese medicine uses.In addition, in recent years, therefrom extracting "
β-Aescin " is a kind of good anti-inflammation detumescence drug, it is anti-inflammatory, impervious go out, eliminate swelling effect, and have remove free radical,
Improve microcirculation, the effect for increasing intravenous tension.It can restore the normal permeability of capillary, increase intravenous tension, improve quiet
Arteries and veins flows back, and improves microcirculation.It is used clinically for the vascular diseases such as cerebral hemorrhage.In eye, from the point of view of pharmacology, should be theoretically
Glaucoma can be treated.
1. play surface-active as the main function ingredient of cream agent in drug.Have simultaneously good anti-
Oxidation and consumer edema effect, play moisture-keeping function.
2. colloidal materials can be done in cosmetics, increase the finish and flexibility of skin, commonly using can be with delaying skin
Aging.
7th, l-cn
L-cn (L-carnitine), also known as l-carnitine or transliteration Carnitine are that one kind promotes adipose conversion as energy
Amino acid, red meat is the main source of l-cn, is had no toxic and side effect to human body.Different types of diet is
Through the l-cn containing 5-100 milligrams, but common people can only take in 50 milligrams from diet daily, and vegetarian's intake is less.
The main Physiological Function of l-cn is that for promotion adipose conversion into energy, body can reduced by taking l-cn
While body fat, losing weight, moisture and muscle are not reduced.Energy is the largest anti-aging strength, and cell has enough energy
Amount will be dynamic.The decrease of cellular energy is one of the reason of it accelerates aging in human aging process, appropriate to supplement
The process that l-cn can delay aging.
In addition, enough energy play a part of a protection for cell, cellular energy is insufficient during body aging,
Supplement l-cn is not only able to provide enough energy, and can keep the strong of immune system, so as to avoid some diseases
Invasion.
Embodiment 1：The compound removes pouch gel, including following components (by weight)：
Embodiment 2：The compound removes pouch gel, including following components (by weight)：
Embodiment 3：The compound removes pouch gel, including following components (by weight)：
The present invention also provides a kind of preparation processes for preparing the compound and removing pouch gel, include the following steps：
Step 1) carries out the deionized water of predetermined weight to be warming up to 90-100 DEG C, and keep the temperature 30 minutes；Cool down deionization
Water extremely, at 40-60 DEG C, respectively by raw material：Eye encloses agent, caffeine silanol, heparin sodium, asiaticosid, safflower extraction
In object, horse chestnut extract, l-carnitine input agitated kettle A, stir evenly for use；
Step 2) by the deionized water of the raw material after cleaning and predetermined amount respectively successively put into extractor in, carry out respectively from
Heart processing, filtering obtain pre-mixing liquor；
Step 3) is by deionized water and carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, Sodium Hyaluronate, rose
Rare hydrosol puts into agitated kettle B and stirs successively, and carbomer, Sodium Hyaluronate uniform dissolution is made in deionized water, and to heat
To 80-100 DEG C, and keep the temperature 30 minutes；
The mixed liquor of step 3) is cooled to 50-70 DEG C by step 4) under stirring；
Step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, is then cooled to
At 40-50 DEG C, be separately added into parahydroxyacet-ophenone, 1,2- hexylene glycols, triethanolamine, and make the pH value of mixture for 5.3~
6.5, and the viscosity of mixture be 15000~20000mpa.s when to get finished product.
Preferably, step 1) deionized water carries out being warming up to 95 DEG C, is subsequently cooled to add in raw material at 50 DEG C.
Preferably, step 3) is by deionized water and carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, hyalomitome
Sour sodium, rose put into agitated kettle B and stir successively, make carbomer, Sodium Hyaluronate uniform dissolution in deionized water,
And 90 DEG C are heated to, and keep the temperature 30 minutes.
Preferably, in step 3), the ratio of deionized water and LUJ20 are 20：1.
Preferably, the mixed liquor of step 3) is cooled to 60 DEG C by step 4) under stirring, and speed of agitator is 30~50
Rev/min.
Preferably, step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, then
When being cooled to 45 DEG C, it is separately added into parahydroxyacet-ophenone, 1,2- hexylene glycols, triethanolamine.
Embodiment one
Step 1) carries out 74.5 parts of deionized water to be warming up to 95 DEG C, and keep the temperature 30 minutes；Deionized water is cooled down to 40
DEG C when, respectively by raw material：6 parts of eye encloses agent, 2 parts of caffeine silanol, 0.2 part of heparin sodium, 0.1 part of centella
In glycosides, 0.2 part of safranine flower extract, 0.2 part of horse chestnut extract, 1 part of l-carnitine input agitated kettle A, stir evenly
For use；More than number is parts by weight；
Step 2) by the deionized water of the raw material after cleaning and predetermined amount respectively successively put into extractor in, carry out respectively from
Heart processing, filtering obtain pre-mixing liquor；
Step 3) is by deionized water and 0.3 part of carbomer, 3 parts of propylene glycol, 5 parts of LUJ20,3 parts of 1,3- fourths two
Alcohol, 0.5 part of D-pantothenyl aleohol, 0.1 part of Sodium Hyaluronate, 3 parts of rose put into agitated kettle B and stir successively, make card
Wave nurse, Sodium Hyaluronate uniform dissolution in deionized water, and are heated to 90 DEG C, and keep the temperature 30 minutes；
The mixed liquor of step 3) is cooled to 60 DEG C by step 4) under stirring；
Step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, is then cooled to 40
DEG C when, be separately added into 0.3 part of parahydroxyacet-ophenone, 0.3 part of 1,2- hexylene glycols, 0.3 part of triethanolamine, and make mixture
PH value for 5.5, and the viscosity of mixture when being 16000mpa.s to get finished product.
Embodiment two
Step 1) carries out 67.3 parts of deionized water to be warming up to 100 DEG C, and keep the temperature 30 minutes；Deionized water is cooled down to 60
DEG C when, respectively by raw material：7 parts of eye encloses agent, 3 parts of caffeine silanol, 0.3 part of heparin sodium, 0.2 part of centella
In glycosides, 0.3 part of safranine flower extract, 0.3 part of horse chestnut extract, 2 parts of l-carnitine input agitated kettle A, stir evenly
For use；More than number is parts by weight；
Step 2) by the deionized water of the raw material after cleaning and predetermined amount respectively successively put into extractor in, carry out respectively from
Heart processing, filtering obtain pre-mixing liquor；
Step 3) is by deionized water and 0.4 part of carbomer, 4 parts of propylene glycol, 5 parts of LUJ20,4 parts of 1,3- fourths two
Alcohol, 1 part of D-pantothenyl aleohol, 0.2 part of Sodium Hyaluronate, 4 parts of rose put into agitated kettle B and stir successively, make card wave
Nurse, Sodium Hyaluronate uniform dissolution in deionized water, and are heated to 90 DEG C, and keep the temperature 30 minutes；
The mixed liquor of step 3) is cooled to 70 DEG C by step 4) under stirring；
Step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, is then cooled to 40
DEG C when, be separately added into 0.3 part of parahydroxyacet-ophenone, 0.3 part of 1,2- hexylene glycols, 0.4 part of triethanolamine, and make mixture
PH value for 6.5, and the viscosity of mixture when being 20000mpa.s to get finished product.
In order to which experiment is compared, the improvement situation of eye part skin is detected, provides the proportioning of one group of pouch gel (by weight
Measure percentage)：
Verification result：
1 analysis table skin irritation (acute skin irritation test) of table
| Name of product | Skin wound repair degree |
| Compare case | 1 |
| Case 1 | 0 |
| Case 2 | 0 |
| Case 3 | 0 |
It can be seen that the compound of present invention addition plant extract composition goes pouch gel product to reduce very skin irritation
It is more.
Multi probe body surface test system MPA9 Germany carries out skin friction power before and after using cosmetics using MPA9
Test, can evaluate the senile-resistant efficacy of cosmetics.
Influence of the table 2 to pouch musculature Flexible change crowd
It can be seen that the compound of present invention addition plant extract composition removes pouch gel product to pouch musculature elasticity
It is significantly improved.
The present invention is described in detail above, described above, only the preferred embodiments of the invention, when cannot
Limit the application practical range, i.e., it is all to make equivalent changes and modifications according to the application range, it all should still belong to covering scope of the present invention
It is interior.
Claims (10)
1. a kind of compound removes pouch gel, it is characterised in that：Including following components (by weight)：
2. compound according to claim 1 removes pouch gel, it is characterised in that：Including following components (by weight)：
3. compound according to claim 1 removes pouch gel, it is characterised in that：Including following components (by weight)：
4. compound according to claim 1 removes pouch gel, it is characterised in that：Including following components (by weight)：
5. the preparation process of pouch gel is gone based on compound described in claim 1, it is characterised in that include the following steps：
Step 1) carries out the deionized water of predetermined weight to be warming up to 90-100 DEG C, and keep the temperature 30 minutes；Cool down deionized water extremely,
At 40-60 DEG C, respectively by raw material：Eye encloses agent, caffeine silanol, heparin sodium, asiaticosid, safranine flower extract, seven
In leaf tree extract, l-carnitine input agitated kettle A, stir evenly for use；
Step 2) puts into the deionized water of the raw material after cleaning and predetermined amount in extractor successively respectively, carries out at centrifugation respectively
Reason, filtering obtain pre-mixing liquor；
Step 3) is pure by deionized water and carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, Sodium Hyaluronate, rose
Dew puts into agitated kettle B and stirs successively, and carbomer, Sodium Hyaluronate uniform dissolution is made in deionized water, and to be heated to 80-
100 DEG C, and keep the temperature 30 minutes；
The mixed liquor of step 3) is cooled to 50-70 DEG C by step 4) under stirring；
Step 5) puts into the pre-mixing liquor of step 2) in agitated kettle B, is mixed and stirred for mixed liquor, is then cooled to 40-50
DEG C when, be separately added into parahydroxyacet-ophenone, 1,2- hexylene glycols, triethanolamine, and the pH value of mixture is made to be 5.3~6.5, and mixed
To get finished product when the viscosity for closing object is 15000~20000mpa.s.
6. compound according to claim 5 goes the preparation process of pouch gel, it is characterised in that：Step 1) deionized water into
Row is warming up to 95 DEG C, is subsequently cooled to add in raw material at 50 DEG C.
7. compound according to claim 5 goes the preparation process of pouch gel, it is characterised in that：Step 3) is by deionized water
It is put into successively in agitated kettle B with carbomer, propylene glycol, LUJ20,1,3-BDO, D-pantothenyl aleohol, Sodium Hyaluronate, rose
And stir, make carbomer, Sodium Hyaluronate uniform dissolution in deionized water, and be heated to 90 DEG C, and keep the temperature 30 minutes.
8. compound according to claim 5 goes the preparation process of pouch gel, it is characterised in that：In step 3), deionization
The ratio of water and LUJ20 are 20：1.
9. compound according to claim 5 goes the preparation process of pouch gel, it is characterised in that：Step 4) is by step 3)
Mixed liquor is cooled to 60 DEG C under stirring, and speed of agitator is 30~50 revs/min.
10. compound according to claim 5 goes the preparation process of pouch gel, it is characterised in that：Step 5) is by step 2)
Pre-mixing liquor put into agitated kettle B, be mixed and stirred for mixed liquor, when being then cooled to 45 DEG C, be separately added into para hydroxybenzene
Ethyl ketone, 1,2- hexylene glycols, triethanolamine.
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| CN201810131866.4A CN108261368A (en) | 2018-02-09 | 2018-02-09 | A kind of compound goes pouch gel and its preparation process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810131866.4A CN108261368A (en) | 2018-02-09 | 2018-02-09 | A kind of compound goes pouch gel and its preparation process |
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| CN108261368A true CN108261368A (en) | 2018-07-10 |
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| CN109044917A (en) * | 2018-10-13 | 2018-12-21 | 明塔生命科技（深圳）有限公司 | Low deuterium rose and preparation method thereof |
| CN109602655A (en) * | 2018-12-25 | 2019-04-12 | 广州葆妍生物科技有限公司 | It is a kind of with it is crease-resistant, remove black eye, the composition for going eye pouch effect and its preparation method and application |
| CN109602654A (en) * | 2018-12-25 | 2019-04-12 | 广州葆妍生物科技有限公司 | A kind of composition and its preparation method and application with eye-care function |
| CN109620745A (en) * | 2018-12-06 | 2019-04-16 | 澳宝化妆品（惠州）有限公司 | A kind of anti-oxidant and anti-facial essence composition just to decline |
| CN109620746A (en) * | 2018-12-06 | 2019-04-16 | 澳宝化妆品（惠州）有限公司 | A kind of Calyx Hibisci Sabdariffae extract and its application in facial-care composition |
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| CN112933034A (en) * | 2021-03-04 | 2021-06-11 | 广州市珍榜日用化工有限公司 | Eye repair and nursing composition capable of removing dark circles, essence emulsion and preparation method |
| CN113057908A (en) * | 2021-04-26 | 2021-07-02 | 广州盛欣化妆品有限公司 | Moisturizing essence and preparation method thereof |
| CN113876656A (en) * | 2021-10-29 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | Black eye and pouch removing soluble beautifying microneedle patch composition and preparation method thereof |
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| CN109044917A (en) * | 2018-10-13 | 2018-12-21 | 明塔生命科技（深圳）有限公司 | Low deuterium rose and preparation method thereof |
| CN109620745A (en) * | 2018-12-06 | 2019-04-16 | 澳宝化妆品（惠州）有限公司 | A kind of anti-oxidant and anti-facial essence composition just to decline |
| CN109620746A (en) * | 2018-12-06 | 2019-04-16 | 澳宝化妆品（惠州）有限公司 | A kind of Calyx Hibisci Sabdariffae extract and its application in facial-care composition |
| CN109602655A (en) * | 2018-12-25 | 2019-04-12 | 广州葆妍生物科技有限公司 | It is a kind of with it is crease-resistant, remove black eye, the composition for going eye pouch effect and its preparation method and application |
| CN109602654A (en) * | 2018-12-25 | 2019-04-12 | 广州葆妍生物科技有限公司 | A kind of composition and its preparation method and application with eye-care function |
| CN110478268A (en) * | 2019-08-08 | 2019-11-22 | 艾伯尔生物科技（重庆）有限公司 | One kind is long-acting to remove eyelid cream and preparation method thereof |
| CN112933034A (en) * | 2021-03-04 | 2021-06-11 | 广州市珍榜日用化工有限公司 | Eye repair and nursing composition capable of removing dark circles, essence emulsion and preparation method |
| CN113057908A (en) * | 2021-04-26 | 2021-07-02 | 广州盛欣化妆品有限公司 | Moisturizing essence and preparation method thereof |
| CN113057908B (en) * | 2021-04-26 | 2022-10-28 | 广州盛欣化妆品有限公司 | Moisturizing essence and preparation method thereof |
| CN113876656A (en) * | 2021-10-29 | 2022-01-04 | 湖北省麦诗特生物科技有限公司 | Black eye and pouch removing soluble beautifying microneedle patch composition and preparation method thereof |
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