CN108251365A - 免疫细胞培养基体系 - Google Patents
免疫细胞培养基体系 Download PDFInfo
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- CN108251365A CN108251365A CN201611233172.9A CN201611233172A CN108251365A CN 108251365 A CN108251365 A CN 108251365A CN 201611233172 A CN201611233172 A CN 201611233172A CN 108251365 A CN108251365 A CN 108251365A
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
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Abstract
Description
实验1 | 实验2 | |
IFN-γ | 1.48x105pg/ml | 1.435x105pg/ml |
TNF-α | 61.1pg/ml | 48.75pg/ml |
Perforin | 19ng/ml | 17.48ng/ml |
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CN201611233172.9A CN108251365B (zh) | 2016-12-28 | 2016-12-28 | 免疫细胞培养基体系 |
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CN201611233172.9A CN108251365B (zh) | 2016-12-28 | 2016-12-28 | 免疫细胞培养基体系 |
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CN108251365A true CN108251365A (zh) | 2018-07-06 |
CN108251365B CN108251365B (zh) | 2020-10-16 |
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109913411A (zh) * | 2019-03-29 | 2019-06-21 | 广东先康达生物科技有限公司 | 有效改善骨髓造血微环境的免疫细胞的制备方法 |
CN109925323A (zh) * | 2019-03-29 | 2019-06-25 | 广东先康达生物科技有限公司 | 有效改善骨髓造血微环境的免疫细胞制剂 |
CN110141582A (zh) * | 2019-06-05 | 2019-08-20 | 广东先康达生物科技有限公司 | 一种具有促进消化道损伤修复的免疫细胞制剂 |
CN110257329A (zh) * | 2019-06-05 | 2019-09-20 | 广东先康达生物科技有限公司 | 一种具有促进消化道损伤修复的免疫细胞的制备方法 |
CN111518751A (zh) * | 2019-11-20 | 2020-08-11 | 广东先康达生物科技有限公司 | 一种体外激活脂肪干细胞转化成原软骨细胞的方法 |
CN112553157A (zh) * | 2020-12-23 | 2021-03-26 | 杭州中赢生物医疗科技有限公司 | 一种淋巴细胞的扩增体系及扩增方法 |
CN114832014A (zh) * | 2022-07-04 | 2022-08-02 | 北京大学人民医院 | Nk细胞的应用、nk细胞回输制剂以及组合制剂 |
CN115094037A (zh) * | 2022-07-19 | 2022-09-23 | 百欧派(天津)生物技术有限公司 | 配合自体血浆使用的具有犬自然杀伤细胞体外激活功能的组合物及其用途 |
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CN101603028A (zh) * | 2008-06-10 | 2009-12-16 | 株式会社Nkbio | 自身活化淋巴细胞培养用培养基组合物 |
CN104593324A (zh) * | 2014-11-28 | 2015-05-06 | 广州赛莱拉干细胞科技股份有限公司 | 一种自然杀伤细胞的培养基及自然杀伤细胞的扩增培养方法 |
CN105101978A (zh) * | 2013-03-27 | 2015-11-25 | 株式会社日本生物治疗研究所 | Nk细胞强化型血液制剂的制造方法 |
CN105219708A (zh) * | 2015-07-21 | 2016-01-06 | 中山大学 | 免疫细胞培养试剂盒、免疫细胞培养方法和应用 |
-
2016
- 2016-12-28 CN CN201611233172.9A patent/CN108251365B/zh active Active
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CN101603028A (zh) * | 2008-06-10 | 2009-12-16 | 株式会社Nkbio | 自身活化淋巴细胞培养用培养基组合物 |
CN105101978A (zh) * | 2013-03-27 | 2015-11-25 | 株式会社日本生物治疗研究所 | Nk细胞强化型血液制剂的制造方法 |
CN104593324A (zh) * | 2014-11-28 | 2015-05-06 | 广州赛莱拉干细胞科技股份有限公司 | 一种自然杀伤细胞的培养基及自然杀伤细胞的扩增培养方法 |
CN105219708A (zh) * | 2015-07-21 | 2016-01-06 | 中山大学 | 免疫细胞培养试剂盒、免疫细胞培养方法和应用 |
Non-Patent Citations (2)
Title |
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SUDO T ET AL.: "OK432-activated natural killer cells enhanced trastuzumab (Herceptin)-mediated antibody-dependent cellular cytotoxicity in patients with advanced cancer.", 《ANTICANCER RES.》 * |
张克等: "两种培养基对细胞因子诱导杀伤细胞体外扩增的影响", 《实用医学杂志》 * |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109913411A (zh) * | 2019-03-29 | 2019-06-21 | 广东先康达生物科技有限公司 | 有效改善骨髓造血微环境的免疫细胞的制备方法 |
CN109925323A (zh) * | 2019-03-29 | 2019-06-25 | 广东先康达生物科技有限公司 | 有效改善骨髓造血微环境的免疫细胞制剂 |
CN110141582A (zh) * | 2019-06-05 | 2019-08-20 | 广东先康达生物科技有限公司 | 一种具有促进消化道损伤修复的免疫细胞制剂 |
CN110257329A (zh) * | 2019-06-05 | 2019-09-20 | 广东先康达生物科技有限公司 | 一种具有促进消化道损伤修复的免疫细胞的制备方法 |
CN111518751A (zh) * | 2019-11-20 | 2020-08-11 | 广东先康达生物科技有限公司 | 一种体外激活脂肪干细胞转化成原软骨细胞的方法 |
CN112553157A (zh) * | 2020-12-23 | 2021-03-26 | 杭州中赢生物医疗科技有限公司 | 一种淋巴细胞的扩增体系及扩增方法 |
CN114832014A (zh) * | 2022-07-04 | 2022-08-02 | 北京大学人民医院 | Nk细胞的应用、nk细胞回输制剂以及组合制剂 |
CN114832014B (zh) * | 2022-07-04 | 2022-10-21 | 北京大学人民医院 | Nk细胞的应用、nk细胞回输制剂以及组合制剂 |
CN115094037A (zh) * | 2022-07-19 | 2022-09-23 | 百欧派(天津)生物技术有限公司 | 配合自体血浆使用的具有犬自然杀伤细胞体外激活功能的组合物及其用途 |
CN115094037B (zh) * | 2022-07-19 | 2023-11-10 | 百欧派(天津)生物技术有限公司 | 配合自体血浆使用的具有犬自然杀伤细胞体外激活功能的组合物及其用途 |
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Effective date of registration: 20220112 Address after: 100850 No. 27 Taiping Road, Beijing, Haidian District Patentee after: ACADEMY OF MILITARY MEDICAL SCIENCES Patentee after: South China Institute of biomedicine Address before: No.1, helix 4 road, International Biological Island, Guangzhou, Guangdong 510200 Patentee before: SOUTH CHINA INSTITUTE OF BIOMEDICINE |