CN108139578B - 分辨至少两个光谱范围的高分辨率扫描显微术 - Google Patents

分辨至少两个光谱范围的高分辨率扫描显微术 Download PDF

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CN108139578B
CN108139578B CN201680057202.7A CN201680057202A CN108139578B CN 108139578 B CN108139578 B CN 108139578B CN 201680057202 A CN201680057202 A CN 201680057202A CN 108139578 B CN108139578 B CN 108139578B
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radiation
channels
detector
spatial
spectral
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CN108139578A (zh
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I.克莱普
R.沃莱申斯基
Y.诺维考
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Carl Zeiss Microscopy GmbH
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    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/361—Optical details, e.g. image relay to the camera or image sensor
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032—Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0072—Optical details of the image generation details concerning resolution or correction, including general design of CSOM objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/06—Means for illuminating specimens
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/58—Optics for apodization or superresolution; Optical synthetic aperture systems
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/04—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres
    • G02B6/06—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres the relative position of the fibres being the same at both ends, e.g. for transporting images
    • G02B6/08—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres the relative position of the fibres being the same at both ends, e.g. for transporting images with fibre bundle in form of plate
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/04—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings formed by bundles of fibres

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
CN201680057202.7A 2015-09-29 2016-09-29 分辨至少两个光谱范围的高分辨率扫描显微术 Active CN108139578B (zh)

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DE102015116435.3A DE102015116435A1 (de) 2015-09-29 2015-09-29 Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Spektralbereiche
DE102015116435.3 2015-09-29
PCT/EP2016/073194 WO2017055405A1 (de) 2015-09-29 2016-09-29 Hochauflösende scanning-mikroskopie mit der unterscheidung mindestens zweier spektralbereiche

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US (1) US10401607B2 (enExample)
JP (1) JP6753935B2 (enExample)
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WO (1) WO2017055405A1 (enExample)

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DE102017113683A1 (de) 2017-06-21 2018-12-27 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie mit der Unterscheidung mindestens zweier Wellenlängenbereiche
IT201800001891A1 (it) * 2018-01-25 2019-07-25 Fondazione St Italiano Tecnologia Metodo di imaging risolto nel tempo ad alta risoluzione spaziale.
CN108897126B (zh) * 2018-08-09 2020-11-03 中国科学院半导体研究所 一种荧光成像系统
US10638061B2 (en) 2018-09-18 2020-04-28 Analog Devices Global Unlimited Company Active-pixel image sensor
DE102018124044B3 (de) 2018-09-28 2020-02-06 Carl Zeiss Microscopy Gmbh Verfahren zum Betreiben eines Vielstrahl-Teilchenstrahlmikroskops und Vielstrahl-Teilchenstrahlsystem
DE102018127281A1 (de) * 2018-10-31 2020-04-30 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren zur Mikroskopie
DE102018128590A1 (de) * 2018-11-14 2020-05-14 Carl Zeiss Microscopy Gmbh Fluktuationsbasierte Fluoreszenzmikroskopie
DE102019100184A1 (de) * 2019-01-07 2020-07-09 Carl Zeiss Microscopy Gmbh Hochauflösende Scanning-Mikroskopie
JP2022524857A (ja) * 2019-03-15 2022-05-10 イルミソニックス インコーポレイテッド 単一光源光音響リモートセンシング（ｓｓ－ｐａｒｓ）
DE102019107267A1 (de) * 2019-03-21 2020-09-24 Carl Zeiss Microscopy Gmbh Verfahren zur hochauflösenden Scanning-Mikroskopie
CN112444506B (zh) * 2019-09-04 2022-03-18 复旦大学 显微成像的方法及装置
DE102020202804A1 (de) 2020-03-05 2021-09-09 Carl Zeiss Microscopy Gmbh Verfahren und Vorrichtung zur Bilderfassung
CN113313778B (zh) * 2021-05-13 2023-02-17 中国科学院深圳先进技术研究院 磁共振图像的重建方法、计算机设备及存储介质
CN114040069B (zh) * 2021-11-05 2023-03-24 东方晶源微电子科技（北京）有限公司 基于探测器通道的自动对焦方法和装置、设备及存储介质

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DE102015116435A1 (de) 2017-03-30
CN108139578A (zh) 2018-06-08
JP6753935B2 (ja) 2020-09-09
US10401607B2 (en) 2019-09-03
JP2018531433A (ja) 2018-10-25
WO2017055405A1 (de) 2017-04-06
US20190056580A1 (en) 2019-02-21

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