CN108136206B - 抗乙型肝炎病毒的组合物和药剂及其用途 - Google Patents

抗乙型肝炎病毒的组合物和药剂及其用途 Download PDF

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CN108136206B
CN108136206B CN201680053632.1A CN201680053632A CN108136206B CN 108136206 B CN108136206 B CN 108136206B CN 201680053632 A CN201680053632 A CN 201680053632A CN 108136206 B CN108136206 B CN 108136206B
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CN108136206A (zh
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P·林姆冯
立川洁
C·以扫
帕德马纳巴·契吾库拉
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/34—Spatial arrangement of the modifications
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CN201680053632.1A 2015-07-17 2016-07-17 抗乙型肝炎病毒的组合物和药剂及其用途 Active CN108136206B (zh)

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US201562193997P 2015-07-17 2015-07-17
US62/193,997 2015-07-17
PCT/US2016/042694 WO2017015175A1 (en) 2015-07-17 2016-07-17 Compositions and agents against hepatitis b virus and uses thereof

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EP3325097B1 (en) 2021-09-01
JP6924744B2 (ja) 2021-08-25
AU2016296592A1 (en) 2018-03-08
US20180371463A1 (en) 2018-12-27
US10961535B2 (en) 2021-03-30
CA2996722A1 (en) 2017-01-26
EP3325097A4 (en) 2019-07-10
TW201803989A (zh) 2018-02-01
JP2018520685A (ja) 2018-08-02
US20170016000A1 (en) 2017-01-19
EP3325097A1 (en) 2018-05-30
WO2017015175A1 (en) 2017-01-26
TWI761311B (zh) 2022-04-21
CN108136206A (zh) 2018-06-08

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