CN108113942A - A kind of sterilization non-water hand cleanser and preparation method thereof - Google Patents

A kind of sterilization non-water hand cleanser and preparation method thereof Download PDF

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Publication number
CN108113942A
CN108113942A CN201810104873.5A CN201810104873A CN108113942A CN 108113942 A CN108113942 A CN 108113942A CN 201810104873 A CN201810104873 A CN 201810104873A CN 108113942 A CN108113942 A CN 108113942A
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Prior art keywords
aloe
alcohol
hand cleanser
water
preparation
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CN201810104873.5A
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Chinese (zh)
Inventor
陈华
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Shanghai Hamei Industrial Development Co Ltd
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Shanghai Hamei Industrial Development Co Ltd
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Priority to CN201810104873.5A priority Critical patent/CN108113942A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

The invention discloses a kind of sterilization non-water hand cleanser and preparation method thereof, including following component:Deionized water, aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine;The raw materials by weight includes, deionized water accounting example 32.98%, aloe accounting example 0.02%, oriental cherry essence accounting example 0.4%, cool feeling agent HK8465 accountings example 0.05%, card ripple U20 accountings example 0.5%, DP300 accountings example 1%, alcohol accounting example 65%, triethanolamine accounting example 0.05%;Hand cleanser of the present invention is cooperated without sticky feel by oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine; it can penetrate into cuticula, increase moisture content of skin, alleviate drying; fill up microgroove; increase skin elasticity, in conclusion the present invention has wide spectrum, efficient bactericidal effect; all there is good killing effect to Escherichia coli and staphylococcus aureus; stability is good, non-stimulated to skin, while has effects that preserving moisture and protecting skin.

Description

A kind of sterilization non-water hand cleanser and preparation method thereof
Technical field
The present invention relates to a kind of hand cleanser and its technical field, more particularly, to a kind of sterilization non-water hand cleanser and its preparation Method.
Background technology
Traditional solid soap becomes easily infected by bacterium and dirt on hand in use, becomes pollution source.And Hand cleanser has sterilization, the low spy for stimulating, avoiding secondary pollution as traditional hand-washing article perfumed soap and the substitute products of hand cleanser Point.In general, hand cleanser is only limitted to the contact surface of hand at the pump head of hand cleanser bottle when cleaning hand, can effectively be avoided Secondary pollution.Meanwhile the formula of hand cleanser is said with respect to perfumed soap than milder, the stimulation of opponent is smaller, to what is be generally infected on hand Pathogen such as Escherichia coli, staphylococcus aureus, the killing effect of Candida albicans have good killing effect.Daily life Ubiquitous spread of germs source moment threatens the health of people in work, thus can fast and easy effective cleaning hand be one The problem of extremely important, hand cleanser in the market need to be used by water, and many occasions are inconvenient with water, it is difficult to be washed one's hands, therefore be exempted from It washes hand cleanser to can be very good to solve the problems, such as that this is awkward, only need to gently smear a bit, be applied to and treat that it is volatilized naturally on hand, you can is full The requirement of sufficient hand disinfection is particularly suitable for water shortages or the inconvenience water fields such as office's office, subway of taking pubic transport, outdoor travel Hand disinfection during conjunction.
Disposable hand cleanser plays an important role of that the i.e. cleanable hand in water source is not required, from water source as new hand cleanser Limitation, use is extremely convenient.The kind of existing disposable hand cleanser is more, but it is most of all there is the defects of certain, it is existing There is disposable hand cleanser in extrusion or ejection, typically no sound or have very of short duration sound, it is interesting general.And not It feels well refrigerant cooling-down effect with ice, particularly in summer in use, skin sense is bad;Being divided into of sterilization unit of some disposable hand cleanser It studies point, it is larger to hand skin irritation, the side effect reactions such as skin irritatin allergy can be caused;Other ingredient is not easy to give birth to Object degradation, hard water resistance poor-performing;More also contain inflammable constituent, store for a long time and unstable separated or gone bad.Such as What, which reduces disinfectant in hand cleanser, to the side effect of hand skin and the hand cleanser of the more stable economy of production, it is disposable to become production The problem of hand cleanser research.
Present invention
The technical problem to be solved by the present invention is to overcome the existing defects, provides a kind of sterilization non-water hand cleanser and its preparation side Method, so as to solve the above problems.
To achieve the above object, the present invention provides following technical solution:A kind of sterilization non-water hand cleanser, including below into Point:Deionized water, aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine;The raw material is pressed Weight percent includes, deionized water accounting example 32.98%, aloe accounting example 0.02%, oriental cherry essence accounting example 0.4%, cool feeling agent HK8465 accountings example 0.05%, card ripple U20 accountings example 0.5%, DP300 accountings example 1%, alcohol accounting example 65%, triethanolamine accounting Example 0.05%;
As a preferred technical solution of the present invention, the dissolution mechanism of the DP300 and alcohol for DP300 first with 95 food Grade alcohol is completely dissolved transparent add in material body.
A kind of sterilization non-water hand cleanser and preparation method thereof, comprises the following steps:
Step 1:The oriental cherry perfume ingredient accounting example 0.4% needs stirring 5 minutes when adding in material body, and ph values control 6.5 ~ Between 7.
Step 2:The card ripple U20 ingredient accountings example 0.5% needs stirring 10 minutes when adding in material body, and the control of ph values exists Between 6.5 ~ 7.
Step 3:The aloe is pulverized, and sieving obtains Alose, adds distilled water immersion, is then heated to boiling, Heat preservation, filtering, is concentrated to give aloe extract.
Step 4:The aloe is pulverized, sieving obtains Alose, adds 25~35min of distilled water immersion, then It is heated to seething with excitement, keeps the temperature 25~35min, filtering is concentrated to give aloe extract, wherein aloe and aloe extract volume ratio (g/mL) it is 0.8~1.2:0.8~1.2.
As a preferred technical solution of the present invention, by the aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine are mixed, then are ultrasonically treated, and stand, and then revolving obtains mixed ethanol extraction Object.
As a preferred technical solution of the present invention, by weight by 32.98% deionized water, 0.02% aloe, 0.4% oriental cherry essence, 0.05% cool feeling agent HK8465,0.5% card ripple U20,1% DP300,65% alcohol, the three of 0.05% Ethanolamine, drying to water content are subsequently added into 45~55 parts of absolute ethyl alcohols mixing after 15~20wt%, to be crushed to 40~50 mesh After uniformly, then 20~30min of supersound process is carried out, add 20~30 parts of absolute ethyl alcohols and stand 1~2h after mixing, then Revolving obtains mixed ethanol extract;
As a preferred technical solution of the present invention, it is fragrant that the deionized water of above-mentioned steps preparation, aloe, oriental cherry are weighed in proportion Essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine add auxiliary material by the customary preparation methods for exempting from hand cleanser It is made.
Compared with prior art, the beneficial effects of the invention are as follows:A kind of sterilization non-water hand cleanser of the present invention and its preparation Method is mixed by the aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine, Then revolving obtains mixed ethanol extract;With extensive antimicrobial spectrum, all have to Escherichia coli and staphylococcus aureus Good killing effect, to shigella dysenteriae, typhoid bacillus, Bordetella pertussis, corynebacterium diphtheriae, Pseudomonas aeruginosa, tubercle bacillus, hammer Bacterium, Diplococcus pneumopniae etc. are respectively provided with inhibitory action, the also effect with resisiting influenza virus;Aloe extract is that antibiotic property is very strong Substance can kill the germs such as a variety of fungies, mould, bacterium, virus, inhibit and the development of eliminating pathogen is bred, aloe polysaccharide There is good nutrition to the skin of human body with vitamin, moisten, whitening effect, further improve the antibacterial effect of the present invention, lead to Cross oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine cooperate so that hand cleanser of the present invention without Sticky feel can be penetrated into cuticula, increase moisture content of skin, alleviate drying, fill up microgroove, increase skin elasticity, comprehensive Upper described, the present invention has wide spectrum, efficient bactericidal effect, all has good kill to Escherichia coli and staphylococcus aureus The effect of going out, stability is good, non-stimulated to skin, while has effects that preserving moisture and protecting skin.
Specific embodiment
Implement below in conjunction with the present invention, the technical solution in the embodiment of the present invention is clearly and completely described, show So, described embodiment is only part of the embodiment of the present invention, instead of all the embodiments, based on the reality in the present invention Apply example, those of ordinary skill in the art's all other embodiments obtained without making creative work all belong to In the scope of protection of the invention.
A kind of sterilization non-water hand cleanser, including following component:Deionized water, aloe, oriental cherry essence, cool feeling agent HK8465, Card ripple U20, DP300, alcohol, triethanolamine;The raw materials by weight includes, deionized water accounting example 32.98%, reed Luxuriant growth accounting example 0.02%, oriental cherry essence accounting example 0.4%, cool feeling agent HK8465 accountings example 0.05%, card ripple U20 accountings example 0.5%, DP300 accountings example 1%, alcohol accounting example 65%, triethanolamine accounting example 0.05%;
The dissolution mechanism of the DP300 and alcohol is first completely dissolved with 95 food-grade alcohol for DP300 and transparent adds material body In.
A kind of sterilization non-water hand cleanser and preparation method thereof, comprises the following steps:
Step 1:The oriental cherry perfume ingredient accounting example 0.4% needs stirring 5 minutes when adding in material body, and ph values control 6.5 ~ Between 7.
Step 2:The card ripple U20 ingredient accountings example 0.5% needs stirring 10 minutes when adding in material body, and the control of ph values exists Between 6.5 ~ 7.
Step 3:The aloe is pulverized, and sieving obtains Alose, adds distilled water immersion, is then heated to boiling, Heat preservation, filtering, is concentrated to give aloe extract.
Step 4:The aloe is pulverized, sieving obtains Alose, adds 25~35min of distilled water immersion, then It is heated to seething with excitement, keeps the temperature 25~35min, filtering is concentrated to give aloe extract, wherein aloe and aloe extract volume ratio (g/mL) it is 0.8~1.2:0.8~1.2.
The aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine are mixed, It is ultrasonically treated, is stood again, then revolving obtains mixed ethanol extract.
By weight by 32.98% deionized water, 0.02% aloe, 0.4% oriental cherry essence, 0.05% cool feeling agent HK8465,0.5% card ripple U20,1% DP300,65% alcohol, 0.05% triethanolamine, it is dry to water content for 15~ After 20wt%, be crushed to 40~50 mesh, be subsequently added into 45~55 parts of absolute ethyl alcohols after mixing, then carry out supersound process 20~ 30min adds 20~30 parts of absolute ethyl alcohols and stands 1~2h after mixing, and then revolving obtains mixed ethanol extract;
Weigh in proportion above-mentioned steps preparation deionized water, aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine add auxiliary material by the customary preparation methods for exempting from hand cleanser and are made.
Concrete principle:In use, aloe is pulverized, sieving obtains Alose, add distilled water immersion 25~ 35min is then heated to boiling, keeps the temperature 25~35min, and filtering is concentrated to give aloe extract, and wherein aloe is extracted with aloe Object volume ratio (g/mL) is 0.8~1.2:0.8~1.2;Aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, wine Essence, triethanolamine are mixed, then are ultrasonically treated, and stand, and then revolving obtains mixed ethanol extract, by weight will 32.98% deionized water, 0.02% aloe, 0.4% oriental cherry essence, 0.05% cool feeling agent HK8465,0.5% card ripple U20, 1% DP300,65% alcohol, 0.05% triethanolamine after drying to water content is 15~20wt%, are crushed to 40~50 Mesh is subsequently added into 45~55 parts of absolute ethyl alcohols after mixing, then carries out 20~30min of supersound process, adds 20~30 parts Absolute ethyl alcohol stands 1~2h after mixing, and then revolving obtains mixed ethanol extract.
A kind of sterilization non-water hand cleanser and preparation method thereof, by the aloe, oriental cherry essence, cool feeling agent HK8465, Card ripple U20, DP300, alcohol, triethanolamine are mixed, and then revolving obtains mixed ethanol extract;With extensive antibacterial Spectrum all has good killing effect, to shigella dysenteriae, typhoid bacillus, pertussis to Escherichia coli and staphylococcus aureus Bacillus, corynebacterium diphtheriae, Pseudomonas aeruginosa, tubercle bacillus, streptococcus, Diplococcus pneumopniae etc. are respectively provided with inhibitory action, also with anti-current The effect of Influenza Virus;Aloe extract is the very strong substance of antibiotic property, can kill the diseases such as a variety of fungies, mould, bacterium, virus Bacterium, inhibits and the development of eliminating pathogen is bred, aloe polysaccharide and vitamin have to the skin of human body good nutrition, moisten, Whitening effect, further improve the present invention antibacterial effect, by oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, Alcohol, triethanolamine cooperate so that hand cleanser of the present invention can penetrate into cuticula without sticky feel, increase skin and contain Water alleviates drying, fills up microgroove, increases skin elasticity, in conclusion the present invention has wide spectrum, efficient bactericidal effect, it is right Escherichia coli and staphylococcus aureus all have good killing effect, and stability is good, non-stimulated to skin, while has guarantor Wet skin-care effect.
Finally it should be noted that:The foregoing is only a preferred embodiment of the present invention, is not intended to limit the invention, Although the present invention is described in detail with reference to the foregoing embodiments, for those skilled in the art, still may be used To modify to the technical solution recorded in foregoing embodiments or carry out equivalent substitution to which part technical characteristic, Within the spirit and principles of the invention, any modifications, equivalent replacements and improvements are made should be included in the present invention's Within protection domain.

Claims (6)

1. a kind of sterilization non-water hand cleanser, which is characterized in that including following component:Deionized water, aloe, oriental cherry essence, cool feeling Agent HK8465, card ripple U20, DP300, alcohol, triethanolamine;The raw materials by weight includes, deionized water accounting example 32.98%th, aloe accounting example 0.02%, oriental cherry essence accounting example 0.4%, cool feeling agent HK8465 accountings example 0.05%, card ripple U20 Accounting example 0.5%, DP300 accountings example 1%, alcohol accounting example 65%, triethanolamine accounting example 0.05%;
A kind of 2. sterilization non-water hand cleanser according to claim 1 and preparation method thereof, which is characterized in that the DP300 With the dissolution mechanism of alcohol first transparent add in material body is completely dissolved with 95 food-grade alcohol for DP300.
3. a kind of sterilization non-water hand cleanser and preparation method thereof, which is characterized in that comprise the following steps:
Step 1:The oriental cherry perfume ingredient accounting example 0.4% needs stirring 5 minutes when adding in material body, and the control of ph values is 6.5 Between~7.
Step 2:The card ripple U20 ingredient accountings example 0.5% needs stirring 10 minutes when adding in material body, and the control of ph values is 6.5 Between~7.
Step 3:The aloe is pulverized, and sieving obtains Alose, adds distilled water immersion, is then heated to boiling, is protected Temperature, filtering, is concentrated to give aloe extract.
Step 4:The aloe is pulverized, sieving obtains Alose, adds 25~35min of distilled water immersion, then heats To boiling, 25~35min is kept the temperature, filtering is concentrated to give aloe extract, wherein aloe and aloe extract volume ratio (g/mL) For 0.8~1.2:0.8~1.2.
4. a kind of sterilization non-water hand cleanser according to claim 1 and preparation method thereof, which is characterized in that by the reed Luxuriant growth, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, triethanolamine are mixed, then are ultrasonically treated, It stands, then revolving obtains mixed ethanol extract.
5. a kind of sterilization non-water hand cleanser according to claim 1 and preparation method thereof, which is characterized in that by weight will 32.98% deionized water, 0.02% aloe, 0.4% oriental cherry essence, 0.05% cool feeling agent HK8465,0.5% card ripple U20,1% DP300,65% alcohol, 0.05% triethanolamine after drying to water content is 15~20wt%, are crushed to 40~50 mesh are subsequently added into 45~55 parts of absolute ethyl alcohols after mixing, then carry out 20~30min of supersound process, add 20 ~30 parts of absolute ethyl alcohols stand 1~2h after mixing, and then revolving obtains mixed ethanol extract;
6. a kind of sterilization non-water hand cleanser according to claim 1 and preparation method thereof, which is characterized in that weigh in proportion The deionized water of above-mentioned steps preparation, aloe, oriental cherry essence, cool feeling agent HK8465, card ripple U20, DP300, alcohol, three ethyl alcohol Amine adds auxiliary material by the customary preparation methods for exempting from hand cleanser and is made.
CN201810104873.5A 2018-02-02 2018-02-02 A kind of sterilization non-water hand cleanser and preparation method thereof Pending CN108113942A (en)

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Cited By (5)

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Publication number Priority date Publication date Assignee Title
CN111329820A (en) * 2020-03-05 2020-06-26 辽宁东科药业有限公司 Hand disinfectant with moisturizing and deodorizing functions and preparation method thereof
CN112137913A (en) * 2020-10-31 2020-12-29 佛山市特能宝化学原料有限公司 Washing-free disinfection gel and preparation method thereof
CN112156055A (en) * 2020-11-06 2021-01-01 义乌市欧雅化妆品有限公司 Natural moisturizing wash-free hand sanitizer and device
CN112754976A (en) * 2021-01-25 2021-05-07 中国石油大学胜利学院 Preparation method of no-clean hand sanitizer
CN113509423A (en) * 2020-04-10 2021-10-19 南京敖广国际贸易有限公司 Water-free disinfection gel hand sanitizer

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111329820A (en) * 2020-03-05 2020-06-26 辽宁东科药业有限公司 Hand disinfectant with moisturizing and deodorizing functions and preparation method thereof
CN113509423A (en) * 2020-04-10 2021-10-19 南京敖广国际贸易有限公司 Water-free disinfection gel hand sanitizer
CN112137913A (en) * 2020-10-31 2020-12-29 佛山市特能宝化学原料有限公司 Washing-free disinfection gel and preparation method thereof
CN112156055A (en) * 2020-11-06 2021-01-01 义乌市欧雅化妆品有限公司 Natural moisturizing wash-free hand sanitizer and device
CN112754976A (en) * 2021-01-25 2021-05-07 中国石油大学胜利学院 Preparation method of no-clean hand sanitizer

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Application publication date: 20180605

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