CN108478472A - A kind of antibiotic skin-care wet tissue annex solution - Google Patents

A kind of antibiotic skin-care wet tissue annex solution Download PDF

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Publication number
CN108478472A
CN108478472A CN201810301209.XA CN201810301209A CN108478472A CN 108478472 A CN108478472 A CN 108478472A CN 201810301209 A CN201810301209 A CN 201810301209A CN 108478472 A CN108478472 A CN 108478472A
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CN
China
Prior art keywords
wet tissue
annex solution
skin
antibiotic skin
care wet
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Pending
Application number
CN201810301209.XA
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Chinese (zh)
Inventor
戴奕杰
田志强
孙端方
李春宇
邵飞龙
杨金川
左泽彦
罗绍楠
张谦
黄家瑞
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GUIZHOU PROVINCE PRODUCT QUALITY SUPERVISION AND INSPECTION INSTITUTE
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GUIZHOU PROVINCE PRODUCT QUALITY SUPERVISION AND INSPECTION INSTITUTE
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Priority to CN201810301209.XA priority Critical patent/CN108478472A/en
Publication of CN108478472A publication Critical patent/CN108478472A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/413Nanosized, i.e. having sizes below 100 nm

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The present invention provides a kind of antibiotic skin-care wet tissue annex solutions, are prepared by the component of following mass fraction:Tea tree ethereal oil 5 10%, nano silver 2 4%, flores aurantii essential oil 3 5%, Cer EOS 1.5%, glycerine 1 3%, watermiscible vitamin E 0 3%, emulsifier 0.1 0.5%, surplus is deionized water.It is simple that the antibiotic skin-care wet tissue adds liquid and preparation method thereof, due to being added to tea tree ethereal oil, nano silver as fungicide, and flores aurantii essential oil, ceramide, glycerine, watermiscible vitamin E are added to as moisturizing ingredient, not only with splendid antibacterial sterilization effect and with skin-protecting functions such as whitening, moisturizings.

Description

A kind of antibiotic skin-care wet tissue annex solution
Technical field
The present invention relates to a kind of wet tissue annex solution more particularly to a kind of antibiotic skin-care wet tissue annex solutions.
Background technology
As people are to quality of life and safe and healthy pay attention to day by day, the use of wet sanitary napkins is increasingly by people Welcome, especially travel outdoors, outdoor activities when, even more become essential belongings.Current wet tissue root on the market According to the annex solution ingredient wherein added, there is the various wet tissues such as antibacterial, moisturizing, taste of dispelling, a great variety.But these wet tissues are usual There are various problems, such as wet tissue annex solution therein only to have certain antibiotic effect, disinfecting, antimicrobial ability general;Or Some ingredients in wet tissue annex solution therein have stimulation, for example contain alcoholic content etc.;Or there is no moisture-keeping efficacy, make With this kind of wet tissue wipe after, skin can dry rapidly it is tight, especially use in winter when, ladies can feel very uncomfortable, after It is continuous necessarily to smear Moisturizer.
Therefore, it is necessary to a kind of new antibacterial sterilization abilities it is strong, safe and with other skin-protecting functions (such as moisturizing, Whitening etc.) wet tissue annex solution.
Invention content
To solve the above problems, the purpose of the present invention is to provide a kind of antibiotic skin-care wet tissue annex solution, not only have Splendid antibacterial sterilization effect, biological safety are high and with skin-protecting functions such as whitening, moisturizings.
Purpose to realize the present invention adopts the technical scheme that:
A kind of antibiotic skin-care wet tissue annex solution, is prepared by the component of following mass fraction:Tea tree ethereal oil 5-10%, Nano silver 2-4%, flores aurantii essential oil 3-5%, Cer EOS -1.5%, glycerine 1-3%, watermiscible vitamin E 0-3%, emulsification Agent 0.1-0.5%, deionized water surplus.
Wherein, the tea tree ethereal oil is medical tea tree ethereal oil.Preferably, the tea tree ethereal oil is in the antibiotic skin-care wet tissue Shared mass fraction is 6-8% in annex solution.
Further, the emulsifier is water emulsifier.Preferably, the emulsifier is carbomer.
Further, the nano silver comes from Nano silver solution, and the mass percentage concentration of the Nano silver solution is 500- The average grain diameter of 1000ppm, nano silver are 1-5nm, using the nano silver compared with small particle, antibacterial activity higher.
It is well known that tea tree ethereal oil is tea tree extract, terpinene-4-alcohol (terpinen-4-ol), australene are mainly contained Alkene (α-pinene), limonene (limonene), α-terpinene (α-terpinene), γ-terpinene (γ-terpinene), The ingredients such as alpha-terpineol (α-terpineol) not only have excellent antibacterial, antiviral and anti-inflammatory effect, also have and receive Pore, Lavender Extract and other effects are held back, is common substance in antibacterial wet tissue, acne-removing inflammation-diminishing skin-protection product.Hammer KA etc. exist 《Antifungal activity of tea tree oil》In show that tea tree ethereal oil can inhibit and kill saccharomycete, skin Tinea bacterium and other filamentous fungis, and it also has Candida albicans preferable inhibition;And Australian University of West Australia One shows (A randomized, controlled trial of tea tree topical preparations Versus a standard topical regimen for the clearance of MRSA colonization), tea Tree essential oil even has staphylococcus aureus certain inhibiting effect.Chinese patent CN 104224923 also turns out tea tree ethereal oil There is good inhibition to staphylococcus aureus, Escherichia coli, Candida albicans (2min bacteriostasis rates are up to 100%). And it is even more not very enumerated about the document using tea tree ethereal oil treatment scytitis, acne.It can be seen that tea tree ethereal oil is a kind of Good antiseptic, but its shortcoming is that its antibacterial disinfection than relatively limited, can only play a part of bacterium, fungi, virus To effect.
Nano silver is a kind of generally acknowledged broad-spectrum sterilization bacteriostatic agent, can kill 650 various bacterias, and in a few millionths Concentration under can kill common bacterium, fungi, mycoplasma, Chlamydia etc. (referring to the following table 1 nano silver sterilization of liquids test As a result, coming from Chinese patent CN 201094754Y).Meanwhile the bactericidal effect that nano silver has is not influenced by pH value, it can be wide Antibacterial is composed, is had no drug resistance and effect is lasting, safety and environmental protection is gone back, is ideal anti-biotic material.
1 nano silver of table sterilizing experimental result (nanometer silver concentration:30ppm)
(data above is derived from northern University of Texas's collargol laboratory study experimental result).
The antibiotic skin-care wet tissue annex solution of the present invention combines tea tree ethereal oil with nano silver, the two synergistic effect, no Only so that disinfection effect so that sterilization, antiviral range are wider, effect is more longlasting, in addition the present invention is using grain size 1- The nano silver of 5nm, nano silver of the antibacterial activity than grain size bigger;Simultaneously using tea tree ethereal oil particular attribute so that it can Anti-inflammatory, calmness, convergent effect are played to skin, thus obtained antibiotic skin-care wet tissue annex solution has had both excellent sterilization and disappeared Malicious effect, while there is the skin-care effect of tea tree ethereal oil.
The other two kinds of important components added in the antibiotic skin-care wet tissue annex solution of the present invention are flores aurantii essential oil and neural acyl Amine.Wherein flores aurantii essential oil can be extracted from the plant of Citrus, and to spend the flores aurantii essential oil quality extracted in petal from bigarabe Most preferably.Flores aurantii essential oil has splendid white-skinned face function, and can play the role of moisturizing, light spot, and energy activating skin promotes skin Skin recycles, and increases skin elasticity.And ceramide is the chief component of horny layer of epidermis, can effectively prevent moisture from skin Skin excessively scatters and disappears, and has excellent moisturizing repairing effect.The complex role of flores aurantii essential oil and ceramide, further enhances pair The moisture-keeping function of skin, at the same also whitening, repair the effect of.
In addition, glycerine also has good moisturizing, moisturizing effect, moistening effect can be further strengthened.
Watermiscible vitamin E is then with certain antioxygenic property and to skin with certain moisturizing, moisturizing effect, together When its also have certain cleaning function.
The preparation method of antibiotic skin-care wet tissue annex solution of the present invention is:It is wet according to previously described antibiotic skin-care of the present invention Towel annex solution each component ratio weighs each component, is added in stirred tank, and stirring to each component is uniformly mixed, then is mixed to gained Liquid carries out sterilization treatment to get to antibiotic skin-care wet tissue annex solution of the present invention.
Further, the Biocidal treatment method is ray sterilizing method, and the ray sterilizing method is Co60γ ray sterilization method, Ultraviolet sterilization or microwave sterilization method.
The purposes of the antibiotic skin-care wet tissue annex solution of the present invention is that can be added in wet tissue or makeup removing cotton to use.
Due to being added to tea tree ethereal oil and nano silver in the antibiotic skin-care wet tissue annex solution of the present invention as fungicide, two Kind of substance synergistic effect enhances sterilizing effect so that antibacterial effect is more longlasting and the bacterial species that can kill are more, clearly It is clean better, while there is the skin care effect of tea tree ethereal oil;And it is added to flores aurantii essential oil and ceramide and then makes the addition Liquid has good skin moisture-keeping effect, while also having certain whitening, repair;Glycerine be common skin care moisturizing at Point, there is good skin moisturizing effect, and add watermiscible vitamin E and then make the annex solution that there is centainly anti-oxidant Property, and further enhance moisturizing, cleaning action.The annex solution can be added in the products such as wet tissue or makeup removing cotton, be used for Cleaning skin, makeup removing etc., can not only play the role of antibiotic and sterilizing, also have good moisturizing, moisten effect to skin, And also there is certain whitening, reparation, sedation.
Specific implementation mode
The present invention is described further with reference to embodiments, it will be appreciated by persons skilled in the art that below Embodiment is only used for explaining the present invention, rather than any limitation is carried out to protection scope of the present invention.
Embodiment 1
The formula of antibiotic skin-care wet tissue annex solution according to the present invention weighs each component in the following proportions:Tea tree ethereal oil 5%, Nano silver 2%, flores aurantii essential oil 4%, Cer EOS %, glycerine 1%, Ka Duomu 0.1%, deionized water surplus.
Used nano silver, will using a concentration of 800ppm, the Nano silver solution that nano silver average grain diameter is 5nm Load weighted each component is added in stirred tank, and stirring to each component is uniformly mixed, then uses Co60γ ray sterilization method is to institute Mixed liquor sterilization treatment to get to antibiotic skin-care wet tissue annex solution sample A of the present invention.
Embodiment 2
The formula of antibiotic skin-care wet tissue annex solution according to the present invention weighs each component in the following proportions:Tea tree ethereal oil 10%, nano silver 4%, flores aurantii essential oil 5%, Cer EOS .5%, glycerine 2%, watermiscible vitamin E 2%, Ka Duomu 0.5%, deionized water surplus.
Used nano silver is the Nano silver solution of 3nm using a concentration of 1000ppm, nano silver average grain diameter, Load weighted each component is added in stirred tank, stirring to each component is uniformly mixed, then using ultraviolet sterilization to gained Mixed liquor sterilization treatment is to get to antibiotic skin-care wet tissue annex solution sample B of the present invention.
Embodiment 3
The formula of antibiotic skin-care wet tissue annex solution according to the present invention weighs each component in the following proportions:Medical tea tree ethereal oil 8%, nano silver 3%, flores aurantii essential oil 3%, Cer EOS .2%, glycerine 3%, watermiscible vitamin E 2%, Ka Duomu 0.3%, deionized water surplus.
Used nano silver, will using a concentration of 500ppm, the Nano silver solution that nano silver average grain diameter is 4nm Load weighted each component is added in stirred tank, and stirring to each component is uniformly mixed, then is mixed to gained using microwave sterilization method Liquid sterilization treatment is to get to antibiotic skin-care wet tissue annex solution sample C of the present invention.
Embodiment 4
The formula of antibiotic skin-care wet tissue annex solution according to the present invention weighs each component in the following proportions:Medical tea tree ethereal oil 6%, nano silver 4%, flores aurantii essential oil 5%, Cer EOS .3%, glycerine 3%, watermiscible vitamin E 3%, Ka Duomu 0.2%, deionized water surplus.
Used nano silver, will using a concentration of 600ppm, the Nano silver solution that nano silver average grain diameter is 2nm Load weighted each component is added in stirred tank, and stirring to each component is uniformly mixed, then uses Co60γ ray sterilization method is to institute Mixed liquor sterilization treatment to get to antibiotic skin-care wet tissue annex solution sample D of the present invention.
Purposes embodiment
4 pieces of the spunlace non-woven cloth of onesize, sterilized processing is taken, is tiled in a reservoir, by enough embodiment 1-4 systems The antibiotic skin-care wet tissue annex solution A-D obtained is added in the container, certain time is stood, until the spunlace non-woven cloth is soaked completely After profit, you can use.
Fungistatic effect is tested
According to GB15979-2002, under test conditions, the antibacterial of the present invention that is added to of gained in purposes embodiment is protected The wet tissue (being indicated respectively with annex solution sample number into spectrum A-D in table) of skin wet tissue annex solution A-D is tested, as a result referring to the following table 2:
According to the above and data are as it can be seen that be added to the wet tissue of the antibiotic skin-care wet tissue annex solution of the present invention, have good Good cleaning, bactericidal effect, 5min or more effects to staphylococcus aureus, Escherichia coli, Candida albicans sterilizing rate can Up to 100%.Since tea tree ethereal oil, the flores aurantii essential oil etc. that contain in annex solution are plant extracts, and nano silver pacifies human body Completely without stimulation, ceramide itself is a kind of ingredient of body skin, therefore the wet tissue for being added to annex solution of the present invention is available It is cleaned in the skin to the place such as hand, arm, foot, can be used for the skin of cleaning body other parts, such as The parts such as human body more sensitive face, perineum.Due to being added to flores aurantii essential oil, ceramide, glycerine and water soluble vitamin life The ingredients such as plain E so that skin sense is good after the wet tissue use, does not have air-dried, tight sense, or even can subsequently not have to coating Other Moisturizers, long-time service will not damage skin, flores aurantii essential oil and ceramide even in etc. Ingredient can also play skin a degree of whitening, repair.
Alternatively, it is also possible to which the antibiotic skin-care wet tissue annex solution of the present invention is added in Ms makeup removing cotton used in everyday, For face's cleaning, makeup removing etc..
The above is only presently preferred embodiments of the present invention, not limits the present invention, this field skill Art personnel can modify or improve present disclosure.Therefore, every without departing from technical solution of the present invention content, foundation Technology contents any simple modification substantially made to the above embodiment of the present invention, equivalent replacement etc. all fall within guarantor of the invention It protects in range.

Claims (10)

1. a kind of antibiotic skin-care wet tissue annex solution, it is characterised in that:The antibiotic skin-care wet tissue annex solution is by following mass fraction Component is prepared:Tea tree ethereal oil 5-10%, nano silver 2-4%, flores aurantii essential oil 3-5%, Cer EOS -1.5%, glycerine 1- 3%, watermiscible vitamin E 0-3%, emulsifier 0.1-0.5%, deionized water surplus.
2. antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:The tea tree ethereal oil is medical tea tree Essential oil.
3. antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:The tea tree ethereal oil is in the antibacterial Shared mass fraction is 6-8% in skin-caring wet tissue annex solution.
4. antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:The nano silver is molten from nano silver The mass percentage concentration of liquid, the Nano silver solution is 500-1000ppm, and the average grain diameter of nano silver is 1-5nm.
5. antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:The emulsifier is aqueous emulsifying Agent.
6. antibiotic skin-care wet tissue annex solution according to claim 5, it is characterised in that:The emulsifier is carbomer.
7. the preparation method of antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:According to claim Each component ratio described in 1 weighs each component, is added in stirred tank, and stirring to each component is uniformly mixed, then is mixed to gained Liquid carries out sterilization treatment to get to antibiotic skin-care wet tissue annex solution of the present invention.
8. the preparation method of antibiotic skin-care wet tissue annex solution according to claim 7, it is characterised in that:The sterilization treatment Method is ray sterilizing method.
9. the preparation method of antibiotic skin-care wet tissue annex solution according to claim 9, it is characterised in that:The ray sterilizing Method is Co60γ ray sterilization method, ultraviolet sterilization or microwave sterilization method.
10. the purposes of antibiotic skin-care wet tissue annex solution according to claim 1, it is characterised in that:The annex solution can add It adds in wet tissue or makeup removing cotton and uses.
CN201810301209.XA 2018-04-04 2018-04-04 A kind of antibiotic skin-care wet tissue annex solution Pending CN108478472A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190505A (en) * 2020-11-16 2021-01-08 四川宸煜林业开发有限责任公司 Sterilized wet tissue containing camphor oil component and preparation method thereof
CN112220691A (en) * 2020-11-16 2021-01-15 四川宸煜林业开发有限责任公司 A wet tissue containing oleum Camphora and its preparation method
CN115569097A (en) * 2022-10-08 2023-01-06 加乘科技(浙江)有限责任公司 Production and preparation method of novel anti-corrosion moisturizing wet tissue

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CN103142419A (en) * 2013-02-26 2013-06-12 金红叶纸业集团有限公司 Skin care composition and facial tissue employing same
CN106038356A (en) * 2016-07-04 2016-10-26 苏州宝丽洁日化有限公司 Physical antibacterial wet wipe and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1524587A (en) * 2003-09-18 2004-09-01 云大科技股份有限公司 Nursing wet towel using tea plant oil as antibacterial and fungistatic agent and production method thereof
WO2006109898A1 (en) * 2005-04-09 2006-10-19 Pion-Tech Co., Ltd Antimicrobial composition containing natural extract, nano silver and natural essential oil
CN103142419A (en) * 2013-02-26 2013-06-12 金红叶纸业集团有限公司 Skin care composition and facial tissue employing same
CN106038356A (en) * 2016-07-04 2016-10-26 苏州宝丽洁日化有限公司 Physical antibacterial wet wipe and preparation method thereof

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112190505A (en) * 2020-11-16 2021-01-08 四川宸煜林业开发有限责任公司 Sterilized wet tissue containing camphor oil component and preparation method thereof
CN112220691A (en) * 2020-11-16 2021-01-15 四川宸煜林业开发有限责任公司 A wet tissue containing oleum Camphora and its preparation method
CN115569097A (en) * 2022-10-08 2023-01-06 加乘科技(浙江)有限责任公司 Production and preparation method of novel anti-corrosion moisturizing wet tissue

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Application publication date: 20180904