CN1080853A - N-(膦酰基乙酰基)-l-天冬氨酸组合物及其作为广谱抗病毒的使用方法 - Google Patents

N-(膦酰基乙酰基)-l-天冬氨酸组合物及其作为广谱抗病毒的使用方法 Download PDF

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Publication number
CN1080853A
CN1080853A CN93104593A CN93104593A CN1080853A CN 1080853 A CN1080853 A CN 1080853A CN 93104593 A CN93104593 A CN 93104593A CN 93104593 A CN93104593 A CN 93104593A CN 1080853 A CN1080853 A CN 1080853A
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CN
China
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treatment
days
virus
pala
hcmv
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Pending
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CN93104593A
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English (en)
Chinese (zh)
Inventor
H·A·布劳
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MedImmune LLC
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MedImmune LLC
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Filing date
Publication date
Priority claimed from US08/032,234 external-priority patent/US5491135A/en
Application filed by MedImmune LLC filed Critical MedImmune LLC
Publication of CN1080853A publication Critical patent/CN1080853A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/212—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN93104593A 1992-03-18 1993-03-18 N-(膦酰基乙酰基)-l-天冬氨酸组合物及其作为广谱抗病毒的使用方法 Pending CN1080853A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85345492A 1992-03-18 1992-03-18
US853,454 1992-03-18
US032,234 1993-03-17
US08/032,234 US5491135A (en) 1992-03-18 1993-03-17 Compositions of N-(phosphonoacetyl)-L-aspartic acid and methods of their use as broad spectrum antivirals

Publications (1)

Publication Number Publication Date
CN1080853A true CN1080853A (zh) 1994-01-19

Family

ID=26708159

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93104593A Pending CN1080853A (zh) 1992-03-18 1993-03-18 N-(膦酰基乙酰基)-l-天冬氨酸组合物及其作为广谱抗病毒的使用方法

Country Status (10)

Country Link
EP (1) EP0660710A1 (es)
JP (1) JPH07507770A (es)
CN (1) CN1080853A (es)
AU (1) AU3965993A (es)
BR (1) BR9306123A (es)
CA (1) CA2109435C (es)
IL (1) IL105090A (es)
IS (1) IS3987A (es)
MX (1) MX9301527A (es)
WO (1) WO1993018763A1 (es)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111317733A (zh) * 2020-03-24 2020-06-23 中国人民解放军海军军医大学 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用
CN111419839A (zh) * 2020-03-31 2020-07-17 远见生物科技（上海）有限公司 利福霉素的新用途
WO2021189444A1 (zh) * 2020-03-24 2021-09-30 中国人民解放军海军军医大学 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440980B1 (en) * 1996-09-17 2002-08-27 Avanir Pharmaceuticals Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US20030100532A1 (en) 1997-02-14 2003-05-29 Gary S. Jacob Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections
EP1030839B1 (en) 1997-11-10 2004-02-04 G.D. SEARLE & CO. Use of alkylated iminosugars to treat multidrug resistance
KR20010040937A (ko) 1998-02-12 2001-05-15 윌리암스 로저 에이 간염 바이러스 감염의 치료를 위한 ｎ-치환된1,5-디데옥시-1,5-이미노-ｄ-글루시톨 화합물의 용도
US6689759B1 (en) 1998-02-12 2004-02-10 G. D. Searle & Co. Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy
US6545021B1 (en) 1999-02-12 2003-04-08 G.D. Searle & Co. Use of substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections
JP2003505501A (ja) 1999-02-12 2003-02-12 ジー・ディー・サール・アンド・カンパニー 肝炎ウィルス感染の処置のためのグルカミン化合物
EP1239923A2 (en) * 1999-12-20 2002-09-18 New Pharma Research Sweden AB Stabilized veterinary compositions comprising more than one antiviral agent
DE10138912A1 (de) * 2001-08-08 2003-02-27 Medinnova Ges Med Innovationen Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen sowie Testsystem zum Auffinden solcher Wirksubstanzen
DE10343365A1 (de) * 2003-09-17 2005-04-14 Biosphings Ag Pharmazeutische Formulierungen von Xanthogenaten und Hemmstoffen der viralen Nukleinsäurereplikation
US8236768B2 (en) 2008-10-03 2012-08-07 3B Pharmaceuticals, Inc. Topical antiviral formulations
WO2021221111A1 (ja) * 2020-04-30 2021-11-04 国立大学法人京都大学 Ｒｎａウイルス関連疾患の予防又は治療剤
EP4313150A1 (en) * 2021-03-26 2024-02-07 Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin Pyrimidine biosynthesis inhibitor combination for use in treating viral infections

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178306A (en) * 1978-08-10 1979-12-11 Parsons Jack L Preparation of N-(phosphonoacetyl)-L-aspartic acid

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111317733A (zh) * 2020-03-24 2020-06-23 中国人民解放军海军军医大学 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用
WO2021189444A1 (zh) * 2020-03-24 2021-09-30 中国人民解放军海军军医大学 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用
CN111317733B (zh) * 2020-03-24 2022-07-12 中国人民解放军海军军医大学 利福霉素类抗生素在制备抗黄热病毒感染药物中的应用
CN111419839A (zh) * 2020-03-31 2020-07-17 远见生物科技（上海）有限公司 利福霉素的新用途

Also Published As

Publication number Publication date
IL105090A0 (en) 1994-08-26
IL105090A (en) 1998-08-16
EP0660710A4 (en) 1995-03-02
JPH07507770A (ja) 1995-08-31
BR9306123A (pt) 1997-08-26
EP0660710A1 (en) 1995-07-05
CA2109435A1 (en) 1993-09-19
MX9301527A (es) 1994-02-28
WO1993018763A1 (en) 1993-09-30
AU3965993A (en) 1993-10-21
IS3987A (is) 1993-09-19
CA2109435C (en) 1997-03-11

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