CN108066216A - A kind of antiallergic releive composition, include its cleanser and preparation method - Google Patents
A kind of antiallergic releive composition, include its cleanser and preparation method Download PDFInfo
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- CN108066216A CN108066216A CN201711454830.1A CN201711454830A CN108066216A CN 108066216 A CN108066216 A CN 108066216A CN 201711454830 A CN201711454830 A CN 201711454830A CN 108066216 A CN108066216 A CN 108066216A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/90—Block copolymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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Abstract
The present invention provides a kind of antiallergic and releives composition, includes its cleanser and preparation method.Antiallergic releives composition using purslane extract magnolia obovata bark extract as primary raw material, adds in 8 esters of 25/30 copolymers of PEG/PPG and olive oil PEG, and wherein purslane extract has effects that anti-irritant, antiallergy, antiallergic are releived；The bark of official magnolia bark extract has effects that antibacterial, anti-inflammatory, anti-oxidant, antiallergic are releived active, the effect of mutual cooperation of purslane extract magnolia obovata extract can promote antiallergic.Antiallergic cleanser of releiving is releived with antiallergic based on composition, add in moisturizer, emollients, detergent and other auxiliary agents, purslane extract magnolia obovata bark extract mutually merges, in use, detergent can clear the dirt of deep skin, and the purslane extract magnolia obovata bark extract of small molecule can quickly enter deep skin, so as to reach the effect of moisturizing is with skin sensitivity is alleviated.
Description
Technical field
The invention belongs to cosmetic fields, and in particular to a kind of antiallergic is releived composition, the cleanser comprising it and preparation
Method.
Background technology
Sensitive is a kind of problem skin, may all have sensibility skin in any skin quality.Just as various skins
Matter may all have aging skin quality, small pox skin quality etc..It is well known that the pathological change of sensitive skin is that cuticula is thinning, subcutaneous hair
The red for being presented on face after thin blood vessel dilatation after extravasated blood is netted.Sensitive skin generally has following skin puzzlement：(1) easily
It is general red to be occurred skin by environmental stimuli, is generated heat, itch, shouting pain；(2) it is serious to be present with red and swollen and fash；(3) with the colour of skin not
Even worry, inflammation, which is taken off, easily leaves mark or spot；(4) skin is thin, and cuticula is not complete, easy furfur；(5) water holding capacity
Difference, the tight drying of skin；(6) there is the unknown small pox of a lot of reasons suddenly, it is all invalid using any product for resolving poxes.It is general to talk
To the origin cause of formation of small pox, usually nothing more than caused by being uncoordinated diet, hormone, pressure or heredity.Then many people can select
It selects using product for resolving poxes, but is found from clinical case, some reasons are unknown, are difficult to the small pox effected a radical cure, and are all because without same
When treat skin allergy caused by recurrent exerbation.
With the continuous deterioration of air and environment, the environmental stimuli that skin is subject to also getting worse, at present, sensitive
The quantity of crowd is constantly soaring, and the daily chemical product that antiallergic is releived is got the favour of people, and still, the cosmetics that antiallergic is releived are good
Green bristlegrass is uneven, and the active ingredient in the cosmetics that antiallergic is releived only is absorbed by the skin and can play a role, but most of
Product can not be absorbed by the skin.
The content of the invention
The composition in order to solve the above technical problems, a kind of antiallergic of present invention offer is releived, includes its cleanser and system
Preparation Method, the present invention are provided the active ingredient that antiallergic is releived using factor differentiation technique and are decomposed into what skin cell easily absorbed
Small molecule first takes the dirt of deep skin out of, then can nutriment quickly be penetrated into skin, be absorbed by cell, in
And free radical, improve the water content of skin, prevention and delay skin aging.
It releives composition the object of the present invention is to provide a kind of antiallergic.
It is a further object of the present invention to provide the cleansers that a kind of antiallergic is releived.
It is to provide a kind of preparation method for the cleanser that antiallergic is releived another mesh of the present invention.
The antiallergic of specific embodiment is releived composition according to the present invention, includes the component of following parts by weight：PEG/PPG-
25/30 3-5 parts of copolymer, 0.5-1.5 parts of the bark of official magnolia bark extract, 2-4 parts of purslane extract and olive oil PEG-8 esters 1-
3 parts.
The present invention adds in PEG/PPG-25/30 copolymers with purslane extract magnolia obovata bark extract primary raw material
With olive oil PEG-8 esters, wherein purslane extract contains alkaloids and Flavonoid substances, can be used as anti-irritant, anti-mistake
Quick functional component is applied to cosmetics, and has anti-drying, increase skin comfort degree, and removing free radical, antiallergic are releived and other effects.
The bark of official magnolia bark extract main chemical compositions are Magnolol and Honokiol, also containing volatile oil and alkaloid etc., are had anti-
Bacterium, anti-inflammatory, anti-oxidant, antiallergic are releived isoreactivity effect.
The antiallergic of specific embodiment is releived composition according to the present invention, it is preferable that the bark of official magnolia bark extract carries
The method is taken to be：It by Magnolia bark, crushes, adds in the ethyl alcohol of 1-10 times of weight, microwave digestion 30-60min is centrifuged, taken
Clear liquid, concentration, drying, obtains the bark of official magnolia bark extract.
The present invention is used in combination using the method for alcohol extracting and Microwave Extraction, is extracted the active ingredient in Magnolia bark, is obtained purity
High the bark of official magnolia bark extract can more rate of acceleration be absorbed by the skin, and alleviate skin sensitivity.
The antiallergic of specific embodiment is releived composition according to the present invention, it is preferable that the extraction of the purslane extract
Method is：Purslane is taken, cleans, dry, pulverize sieving, add in the water of 2-5 times of weight, be heated to 25-35 DEG C, is then added in fine
The plain enzyme of dimension and pectase, keep the temperature 30-50min, then ultrasonic extraction 20-40min, and centrifugation takes supernatant, is concentrated and dried, obtains
Extract I adds in 1-2 times of ethyl alcohol of filter residue weight into filter residue, extracts 20-40min, centrifuges, obtains filtrate, dense
Contracting, dry, extract II merges extract I and extract II, obtains the purslane extract.
Purslane extract has antibacterial, anti-inflammation detumescence, relaxed muscle, reducing blood lipid and antiatherosclerosis, anti-aging
The effects that, the present invention first crushes purslane, adds in cellulase and pectase, digests cellulose and pectin therein, then
It carries out water to carry, the aqueous soluble active constituent in purslane is proposed, alcohol extracting then is carried out to its filter residue, by alcohol-soluble in purslane
Active ingredient proposes that the active ingredient in purslane in extract is presented with the small molecule easily absorbed, improves skin and it is absorbed
Efficiency.
The antiallergic of specific embodiment is releived composition according to the present invention, it is preferable that the addition of the cellulase is
The 0.1-0.2wt% of purslane, the addition of the pectase are the 0.1-0.2wt% of purslane.
The cleanser that the antiallergic of specific embodiment is releived according to the present invention, includes the component of following parts by weight, and antiallergic is relaxed
Slow 6.5-13.5 parts of composition, 20-25 parts of water, 16-24 parts of moisturizer, 17-29 parts of emollients, 13-19 parts of detergent are antistatic
4.5-5.5 part of 2-4 parts of agent, 0.02-0.06 parts of chelating agent and pH adjusting agent, antiallergic composition of releiving include following parts by weight
Component：3-5 parts of PEG/PPG-25/30 copolymers, 2-4 parts of purslane extract, 0.5-1.5 parts of the bark of official magnolia bark extract, olive
1-3 parts of olive oil PEG-8 esters.
Antiallergic provided by the invention is releived cleanser, is included antiallergic and is releived composition and moisturizer and detergent,
Middle detergent can effectively remove the dirt of skin, then the moisturizing ingredient in cleanser and antiallergic releive active ingredient can be fast
Speed reaches the deep layer of skin, and moisturizing and supply nutriment, the sensitivity soothed the skin are carried out to skin, while has certain resist
Oxidation and anti-aging effects.
The cleanser that the antiallergic of specific embodiment is releived according to the present invention, it is preferable that the component further includes oxybenzene first
0.05-0.15 parts of 0.15-0.25 parts of ester and Nipasol.
In order to increase the shelf-life of cleanser, the present invention is additionally added micro preservative so that the shelf-life of product was from 1 year
It improves to 2.5 years.
The cleanser that the antiallergic of specific embodiment is releived according to the present invention, it is preferable that the moisturizer includes propylene glycol
8-12 parts and 8-12 parts of glycerine；
The emollients include 6-10 parts of stearic acid, 6-10 parts of myristic acid, 4-6 parts of polyethylene glycol-8 and ethylene glycol two
1-3 parts of stearate；
The detergent includes 5-7 parts of lauric acid, 5-7 parts of cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium
3-5 parts；
The antistatic agent is polyquaternium -7；
The chelating agent is EDETATE SODIUM；
The pH adjusting agent is potassium hydroxide.
The present invention selects above-mentioned raw material, by the study found that can cooperate between them, playing the anti-of cleanser
The quick effect of releiving.
The preparation method for the cleanser that the antiallergic of specific embodiment is releived according to the present invention, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7, glycol distearate, hydroxyl
Benzene methyl and Nipasol, are heated to 75-85 DEG C, are uniformly mixed, obtain oil mixture；
(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium,
68-72 DEG C is heated to, is uniformly mixed, then adds in potassium hydroxide, adjusts pH to 6.8-8, is uniformly mixed, is obtained water and mix
Object；
(3) aqueous mixture and oil mixture are mixed, carries out emulsifying, then add in PEG/PPG-25/
30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are uniformly mixed, obtain the antiallergic and relax
Slow cleanser.
The preparation method for the cleanser that the antiallergic of specific embodiment is releived according to the present invention, it is preferable that in step (3),
The temperature of the emulsifying is 68-72 DEG C, time 20-40min.
The preparation method for the cleanser that the antiallergic of specific embodiment is releived according to the present invention, it is preferable that in step (3),
After emulsifying, 58-62 DEG C is cooled to, then adds in PEG/PPG-25/30 copolymers, purslane extract, Magnolia bark
Extract and olive oil PEG-8 esters are uniformly mixed, are cooled to room temperature, obtain the cleanser that the antiallergic is releived.
The preparation method for the cleanser that antiallergic provided by the invention is releived, it is easy to operate, it is suitble to industrialized production, obtains
Antiallergic is releived cleanser stable homogeneous, and antiallergic, which is releived, to work well.
Beneficial effects of the present invention are：
The composition 1. a kind of antiallergic of present invention offer is releived, includes its cleanser and preparation method.Antiallergic is releived combination
Object adds in PEG/PPG-25/30 copolymers and olive oil PEG-8 with purslane extract magnolia obovata bark extract primary raw material
Esters, wherein purslane extract contain alkaloids and Flavonoid substances, have effects that anti-irritant, antiallergy, and with anti-
The effect of dry, increase skin comfort degree, removing free radical, antiallergic are releived；The bark of official magnolia bark extract main chemical compositions are thickness
Plain phenol and honokiol, also containing volatile oil and alkaloid, have effects that antibacterial, anti-inflammatory, anti-oxidant, antiallergic releive it is active,
The effect of mutual cooperation of purslane extract magnolia obovata extract can promote antiallergic.
2. antiallergic is releived, cleanser is releived with antiallergic based on composition, add in moisturizer, emollients, detergent and other help
Agent, purslane extract magnolia obovata bark extract mutually merge, and in use, detergent can be by the dirt of deep skin
Dirt clears, and the purslane extract magnolia obovata bark extract of small molecule can quickly enter deep skin, so as to
The effect of reaching moisturizing and alleviating skin sensitivity.
3. the preparation method for the cleanser that antiallergic provided by the invention is releived, easy to operate, it is suitble to industrialized production, obtains
Antiallergic releive cleanser stable homogeneous, antiallergic, which is releived, to work well.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all on the premise of creative work is not made
Other embodiment belongs to the scope that the present invention is protected.
Embodiment 1
Antiallergic is releived composition, includes the component of following parts by weight：3 parts of PEG/PPG-25/30 copolymers, Magnolia bark carries
Take 1 part of 0.5 part of object, 2 parts of purslane extract and olive oil PEG-8 esters.
The extracting method of above-mentioned the bark of official magnolia bark extract is：Magnolia bark is cleaned, dry, pulverize sieving, adds in 1 times of weight
The ethyl alcohol of amount, microwave digestion 60min take supernatant, and concentration, drying obtain the bark of official magnolia bark extract.
The extracting method of above-mentioned purslane extract is：Purslane is taken, cleans, dry, pulverize sieving, add in 2 times of weight
Part water, is heated to 25 DEG C, then adds in cellulase and pectase, keeps the temperature 50min, then ultrasonic extraction 40min, and centrifugation takes
Supernatant is concentrated and dried, obtains extract I, and 1 times of ethyl alcohol of filter residue weight is added in into filter residue, extracts 20min, centrifugation point
From obtaining filtrate, concentrate, dry, extract II merges extract I and extract II, obtains the purslane extract.
The cleanser that antiallergic is releived includes the component of following parts by weight：Above-mentioned antiallergic is releived 6.5 parts of composition, 20 parts of water,
8 parts of propylene glycol, 8 parts of glycerine, 6 parts of stearic acid, 6 parts of myristic acid, 4 parts of polyethylene glycol-8,1 part of glycol distearate, the moon
5 parts of cinnamic acid, 5 parts of cocounut oil acyl both sexes base diethyl acid disodium, 3 parts of cocounut oil acyl glycine potassium, 2 parts of polyquaternium -7, EDETATE SODIUM
0.02 part and 4.5 parts of potassium hydroxide.
The preparation method for the cleanser that above-mentioned antiallergic is releived, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7 and glycol distearate,
75 DEG C are heated to, is uniformly mixed, obtains oil mixture；
(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium,
68 DEG C are heated to, is uniformly mixed, then adds in potassium hydroxide, adjusts pH to 6.8, is uniformly mixed, obtains aqueous mixture；
(3) aqueous mixture and oil mixture are mixed, carries out emulsifying, then add in PEG/PPG-25/
30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are uniformly mixed, obtain the antiallergic and relax
Slow cleanser.
Embodiment 2
Antiallergic is releived composition, includes the component of following parts by weight：5 parts of PEG/PPG-25/30 copolymers, Magnolia bark carries
Take 3 parts of 1.5 parts of object, 4 parts of purslane extract and olive oil PEG-8 esters.
The extracting method of above-mentioned the bark of official magnolia bark extract is：Magnolia bark is cleaned, dry, pulverize sieving, adds in 10 times
The ethyl alcohol of weight, microwave digestion 20min take supernatant, and concentration, drying obtain the bark of official magnolia bark extract.
The extracting method of above-mentioned purslane extract is：Purslane is taken, cleans, dry, pulverize sieving, add in 5 times of weight
Part water, is heated to 35 DEG C, then adds in cellulase and pectase, keeps the temperature 30min, then ultrasonic extraction 40min, and centrifugation takes
Supernatant is concentrated and dried, obtains extract I, and 2 times of ethyl alcohol of filter residue weight is added in into filter residue, extracts 40min, centrifugation point
From obtaining filtrate, concentrate, dry, extract II merges extract I and extract II, obtains the purslane extract.
The cleanser that antiallergic is releived includes the component of following parts by weight：Above-mentioned antiallergic is releived 13.5 parts of composition, water 25
Part, 12 parts of propylene glycol, 12 parts of glycerine, 10 parts of stearic acid, 10 parts of myristic acid, 6 parts of polyethylene glycol-8, ethylene glycol distearyl acid
3 parts of ester, 7 parts of lauric acid, 7 parts of cocounut oil acyl both sexes base diethyl acid disodium, 5 parts of cocounut oil acyl glycine potassium, 4 parts of polyquaternium -7,
5.5 parts of 0.06 part of EDETATE SODIUM and potassium hydroxide.
The preparation method for the cleanser that above-mentioned antiallergic is releived, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7 and glycol distearate,
85 DEG C are heated to, is uniformly mixed, obtains oil mixture；
(2) water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium are added
Heat is uniformly mixed to 72 DEG C, then adds in potassium hydroxide, adjusts pH to 8, is uniformly mixed, is obtained aqueous mixture；
(3) aqueous mixture and oil mixture are mixed, carries out emulsifying, then add in PEG/PPG-25/
30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are uniformly mixed, obtain the antiallergic and relax
Slow cleanser.
Embodiment 3
Antiallergic is releived composition, includes the component of following parts by weight：4 parts of PEG/PPG-25/30 copolymers, Magnolia bark carries
Take 2 parts of 1 part of object, 3 parts of purslane extract and olive oil PEG-8 esters.
The extracting method of above-mentioned the bark of official magnolia bark extract is：Magnolia bark is cleaned, dry, pulverize sieving, adds in 5 times of weights
The ethyl alcohol of amount, microwave digestion 30min take supernatant, and concentration, drying obtain the bark of official magnolia bark extract.
The extracting method of above-mentioned purslane extract is：Purslane is taken, cleans, dry, pulverize sieving, add in 4 times of weight
Part water, is heated to 30 DEG C, then adds in cellulase and pectase, the addition of the cellulase is purslane
0.1wt%, the addition of the pectase are the 0.1wt% of purslane, keep the temperature 40min, then ultrasonic extraction 30min, centrifugation,
Supernatant is taken, is concentrated and dried, obtains extract I, 1.5 times of ethyl alcohol of filter residue weight is added in into filter residue, extracts 30min, from
The heart separates, and obtains filtrate, concentrates, dry, and extract II merges extract I and extract II, obtains the purslane extraction
Object.
The cleanser that antiallergic is releived includes the component of following parts by weight：Above-mentioned antiallergic is releived 10 parts of composition, water 22.95
Part, 10 parts of propylene glycol, 10 parts of glycerine, 8 parts of stearic acid, 8 parts of myristic acid, 5 parts of polyethylene glycol-8, glycol distearate 2
Part, 6 parts of lauric acid, 6 parts of cocounut oil acyl both sexes base diethyl acid disodium, 4 parts of cocounut oil acyl glycine potassium, 3 parts of polyquaternium -7, EDTA
0.05 part of disodium, 5.2 parts of 0.15 part of methyl hydroxybenzoate, 0.05 part of Nipasol and potassium hydroxide.
The preparation method for the cleanser that above-mentioned antiallergic is releived, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7, glycol distearate, hydroxyl
Benzene methyl and Nipasol are heated to 80 DEG C, are uniformly mixed, obtain oil mixture；
(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium,
70 DEG C are heated to, is uniformly mixed, then adds in potassium hydroxide, adjusts pH to 7.2, is uniformly mixed, obtains aqueous mixture；
(3) aqueous mixture and oil mixture are mixed, in 68 DEG C of emulsifying 40min, is cooled to 58 DEG C, so
PEG/PPG-25/30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are added in afterwards, and mixing is equal
It is even, it is cooled to room temperature, it is filling, obtain the cleanser that the antiallergic is releived.
Embodiment 4
Antiallergic is releived composition, includes the component of following parts by weight：4 parts of PEG/PPG-25/30 copolymers, Magnolia bark carries
Take 2 parts of 1 part of object, 3 parts of purslane extract and olive oil PEG-8 esters.
The extracting method of above-mentioned the bark of official magnolia bark extract is：Magnolia bark is cleaned, dry, pulverize sieving, adds in 5 times of weights
The ethyl alcohol of amount, microwave digestion 30min take supernatant, and concentration, drying obtain the bark of official magnolia bark extract.
The extracting method of above-mentioned purslane extract is：Purslane is taken, cleans, dry, pulverize sieving, add in 4 times of weight
Part water, is heated to 30 DEG C, then adds in cellulase and pectase, the addition of the cellulase is purslane
0.2wt%, the addition of the pectase are the 0.2wt% of purslane, keep the temperature 40min, then ultrasonic extraction 30min, centrifugation,
Supernatant is taken, is concentrated and dried, obtains extract I, 1.5 times of ethyl alcohol of filter residue weight is added in into filter residue, extracts 30min, from
The heart separates, and obtains filtrate, concentrates, dry, and extract II merges extract I and extract II, obtains the purslane extraction
Object.
The cleanser that antiallergic is releived includes the component of following parts by weight：Above-mentioned antiallergic is releived 10 parts of composition, water 22.95
Part, 10 parts of propylene glycol, 10 parts of glycerine, 8 parts of stearic acid, 8 parts of myristic acid, 5 parts of polyethylene glycol-8, glycol distearate 2
Part, 6 parts of lauric acid, 6 parts of cocounut oil acyl both sexes base diethyl acid disodium, 4 parts of cocounut oil acyl glycine potassium, 3 parts of polyquaternium -7, EDTA
0.15 part of 0.05 part of disodium, 0.25 part of methyl hydroxybenzoate and Nipasol and 5.2 parts of potassium hydroxide.
The preparation method for the cleanser that above-mentioned antiallergic is releived, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7, glycol distearate, hydroxyl
Benzene methyl and Nipasol are heated to 80 DEG C, are uniformly mixed, obtain oil mixture；
(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium,
70 DEG C are heated to, is uniformly mixed, then adds in potassium hydroxide, adjusts pH to 7.2, is uniformly mixed, obtains aqueous mixture；
(3) aqueous mixture and oil mixture are mixed, in 72 DEG C of emulsifying 40min, is cooled to 62 DEG C, so
PEG/PPG-25/30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are added in afterwards, and mixing is equal
It is even, it is cooled to room temperature, it is filling, obtain the cleanser that the antiallergic is releived.
Embodiment 5
Antiallergic is releived composition, includes the component of following parts by weight：4 parts of PEG/PPG-25/30 copolymers, Magnolia bark carries
Take 2 parts of 1 part of object, 3 parts of purslane extract and olive oil PEG-8 esters.
The extracting method of above-mentioned the bark of official magnolia bark extract is：Magnolia bark is cleaned, dry, pulverize sieving, adds in 5 times of weights
The ethyl alcohol of amount, microwave digestion 30min take supernatant, and concentration, drying obtain the bark of official magnolia bark extract.
The extracting method of above-mentioned purslane extract is：Purslane is taken, cleans, dry, pulverize sieving, add in 4 times of weight
Part water, is heated to 30 DEG C, then adds in cellulase and pectase, the addition of the cellulase is purslane
0.15wt%, the addition of the pectase are the 0.15wt% of purslane, keep the temperature 40min, then ultrasonic extraction 30min, from
The heart takes supernatant, is concentrated and dried, obtains extract I, and 1.5 times of ethyl alcohol of filter residue weight is added in into filter residue, extracts 30min,
It centrifuges, obtains filtrate, concentrate, dry, extract II merges extract I and extract II, obtains the purslane extraction
Object.
The cleanser that antiallergic is releived includes the component of following parts by weight：Above-mentioned antiallergic is releived 10 parts of composition, water 22.95
Part, 10 parts of propylene glycol, 10 parts of glycerine, 8 parts of stearic acid, 8 parts of myristic acid, 5 parts of polyethylene glycol-8, glycol distearate 2
Part, 6 parts of lauric acid, 6 parts of cocounut oil acyl both sexes base diethyl acid disodium, 4 parts of cocounut oil acyl glycine potassium, 3 parts of polyquaternium -7, EDTA
5.2 parts of 0.05 part of disodium, 0.2 part of methyl hydroxybenzoate, 0.1 part of Nipasol and potassium hydroxide.
The preparation method for the cleanser that above-mentioned antiallergic is releived, comprises the following steps：
(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7, glycol distearate, hydroxyl
Benzene methyl and Nipasol are heated to 80 DEG C, are uniformly mixed, obtain oil mixture；
(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium,
70 DEG C are heated to, is uniformly mixed, then adds in potassium hydroxide, adjusts pH to 7.2, is uniformly mixed, obtains aqueous mixture；
(3) aqueous mixture and oil mixture are mixed, in 70 DEG C of emulsifying 30min, is cooled to 60 DEG C, so
PEG/PPG-25/30 copolymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are added in afterwards, and mixing is equal
It is even, it is cooled to room temperature, it is filling, obtain the cleanser that the antiallergic is releived.
Test example
Call-up age is 20-45 Sui skin hypersensitivity redness, the volunteer of dry furfur, female volunteers 50, male
Volunteer 50, men and women's mixed allocation are randomly divided into two groups, are respectively test group and control group.
Test group：The daily cleanser obtained using the embodiment of the present invention 5 is washed one's face, and once in the morning and once at night, cleanser is on the face
Residence time is maintained within 1min, does not apply other skin care item, and test period is 30 days.
Control group：Daily using commercially available facial cleanser face cleaning, once in the morning and once at night, cleanser is maintained in residence time on the face
Within 1min, other skin care item are not applied, and test period is 30 days.Every 10 days statistics first use effects.
Evaluation criterion：Effectively：Redness disappears, and desquamation of skin phenomenon, which is reduced, is presented water profit state.It is invalid：Symptom is unchanged,
Even aggravate.It the results are shown in Table 1.
1 antiallergic result of the test of table
From the results shown in Table 1, the volunteer of control group also has partial skin condition responsive to be improved, this be because
Be human body have certain self-repairing capability, and compared with the control group antiallergic provided by the invention releive cleanser can be rapid
Effectively alleviate the redness of skin and desquamation of skin problem, wherein using after 30, there are 42 people's situations to obtain in 50 volunteers bright
Aobvious to improve, effective percentage is 84%.
The above description is merely a specific embodiment, but protection scope of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can readily occur in change or replacement, should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
- The composition 1. a kind of antiallergic is releived, which is characterized in that include the component of following parts by weight：PEG/PPG-25/30 copolymers 3-5 parts, 0.5-1.5 parts of the bark of official magnolia bark extract, 1-3 parts of 2-4 parts of purslane extract and olive oil PEG-8 esters.
- The composition 2. antiallergic according to claim 1 is releived, which is characterized in that the extraction side of the bark of official magnolia bark extract Method is：It by Magnolia bark, crushing, adds in the ethyl alcohol of 1-10 times of weight, microwave digestion 30-60min centrifuges, takes supernatant, Concentration, drying, obtain the bark of official magnolia bark extract.
- The composition 3. antiallergic according to claim 1 is releived, which is characterized in that the extracting method of the purslane extract For：Purslane is taken, cleans, dry, pulverize sieving, add in the water of 2-5 times of weight, be heated to 25-35 DEG C, then add in cellulose Enzyme and pectase keep the temperature 30-50min, then ultrasonic extraction 20-40min, and centrifugation takes supernatant, is concentrated and dried, is extracted Object I adds in 1-2 times of ethyl alcohol of filter residue weight into filter residue, extracts 20-40min, centrifuges, obtains filtrate, concentrates, and does Dry, extract II merges extract I and extract II, obtains the purslane extract.
- The composition 4. antiallergic according to claim 3 is releived, which is characterized in that the addition of the cellulase is dent The 0.1-0.2wt% of amaranth, the addition of the pectase are the 0.1-0.2wt% of purslane.
- 5. the cleanser that a kind of antiallergic is releived, which is characterized in that include the component of following parts by weight：Any institutes of claim 1-4 The antiallergic stated is releived 6.5-13.5 parts of composition, 20-25 parts of water, 16-24 parts of moisturizer, 17-29 parts of emollients, detergent 13- 19 parts, 2-4 parts of antistatic agent, 4.5-5.5 parts of 0.02-0.06 parts of chelating agent and pH adjusting agent.
- 6. the cleanser that antiallergic according to claim 5 is releived, which is characterized in that the component further includes methyl hydroxybenzoate 0.15-0.25 parts and 0.05-0.15 parts of Nipasol.
- 7. the cleanser that antiallergic according to claim 6 is releived, which is characterized in thatThe moisturizer includes 8-12 parts of 8-12 parts of propylene glycol and glycerine；The emollients include 6-10 parts of stearic acid, 6-10 parts of myristic acid, 4-6 parts of polyethylene glycol-8 and ethylene glycol distearyl 1-3 parts of acid esters；The detergent includes 5-7 parts of lauric acid, 5-7 parts of cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium 3-5 Part；The antistatic agent is polyquaternium -7；The chelating agent is EDETATE SODIUM；The pH adjusting agent is potassium hydroxide.
- 8. the preparation method for the cleanser that the antiallergic described in claim 7 is releived, which is characterized in that comprise the following steps：(1) by stearic acid, lauric acid, myristic acid, polyethylene glycol-8, polyquaternium -7, glycol distearate, oxybenzene first Ester and Nipasol, are heated to 75-85 DEG C, are uniformly mixed, obtain oil mixture；(2) by water, propylene glycol, glycerine, EDETATE SODIUM, cocounut oil acyl both sexes base diethyl acid disodium and cocounut oil acyl glycine potassium, heating It to 68-72 DEG C, is uniformly mixed, then adds in potassium hydroxide, adjust pH to 6.8-8, be uniformly mixed, obtain aqueous mixture；(3) aqueous mixture and oil mixture are mixed, carries out emulsifying, then added in PEG/PPG-25/30 and be total to Polymers, purslane extract, the bark of official magnolia bark extract and olive oil PEG-8 esters are uniformly mixed, obtain what the antiallergic was releived Cleanser.
- 9. the preparation method for the cleanser that antiallergic according to claim 8 is releived, which is characterized in that described in step (3) The temperature of emulsifying is 68-72 DEG C, time 20-40min.
- 10. the preparation method for the cleanser that antiallergic according to claim 8 is releived, which is characterized in that in step (3), After matter emulsification, 58-62 DEG C is cooled to, PEG/PPG-25/30 copolymers, purslane extract, Magnolia bark is then added in and carries Object and olive oil PEG-8 esters are taken, is uniformly mixed, is cooled to room temperature, obtains the cleanser that the antiallergic is releived.
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| CN113730307A (en) * | 2021-09-22 | 2021-12-03 | 上海溪上生物科技有限公司 | Anti-allergy and soothing composition containing purslane and Cladosiphon starwort extract |
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Application publication date: 20180525 |