CN108030099A - It is a kind of effectively to relieve stress the prescription nutrition food and preparation method for improving sleep - Google Patents
It is a kind of effectively to relieve stress the prescription nutrition food and preparation method for improving sleep Download PDFInfo
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- CN108030099A CN108030099A CN201711499496.1A CN201711499496A CN108030099A CN 108030099 A CN108030099 A CN 108030099A CN 201711499496 A CN201711499496 A CN 201711499496A CN 108030099 A CN108030099 A CN 108030099A
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- nutraceutical
- improving sleep
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- beverage
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- 235000013305 food Nutrition 0.000 title claims abstract description 28
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 230000035764 nutrition Effects 0.000 title claims abstract description 22
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 47
- DATAGRPVKZEWHA-YFKPBYRVSA-N N(5)-ethyl-L-glutamine Chemical compound CCNC(=O)CC[C@H]([NH3+])C([O-])=O DATAGRPVKZEWHA-YFKPBYRVSA-N 0.000 claims abstract description 46
- 239000000843 powder Substances 0.000 claims abstract description 39
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 34
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- 229960003692 gamma aminobutyric acid Drugs 0.000 claims abstract description 24
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- 230000002747 voluntary effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The present invention relates to a kind of prescription nutrition food for effectively relieving stress improvement sleep and preparation method, the prescription nutrition food to be made of following component by weight percentage:4.5 62.5.0% of gamma aminobutyric acid, tealeaves theanine 4.0 50.0%, casein hydrolysate 3.0 35%, asparagus powder 10 25%, spiny jujuba seed powder 8 25%, L calcium lactates 1.53 5.90%, vitamin B6 0.0007 0.0022% and sweetener 10 25%;The formulation of the prescription nutrition food is pressed candy, solid beverage and beverage.The prescription nutrition food of the present invention is natural, has no toxic side effect, and can effectively relieve stress, and improves sleep quality.
Description
Technical field
The present invention relates to a kind of nutraceutical and preparation method, and in particular to a kind of effectively relieve stress improves matching somebody with somebody for sleep
Square nutraceutical and preparation method.
Background technology
As the fast development of society, the fierceness of social competition, the live and work pressure of people are increasing.Human body is such as
Fruit is in the case that nervous and pressure is excessive for a long time, and considerable influence is be easy to cause to the health of body, not only influences to sleep
Dormancy quality, and physical function can be caused to break down.
Insomnia, i.e. sleep disorder often show as difficulty falling asleep, sleep is intermittently discontinuous, prematurely wakes up, it is awake after not
It can be further continued for sleeping, having sleep insufficiency, malaise, burnout sensation etc..Insomnia is mainly due to environmental factor, psychological factor, essence
Refreshing factor causes, psychological factor such as anxiety, dysphoria or it is depressed, mood is unhappy etc., be all the important of cause insomnia
Reason.Strike, work and change of the pressure learnt, not accomplished wish and social environment of life etc., can make one to produce psychology
And physiological reaction, cause the dysfunction of nervous system, cause the dysfunction of brain, sleep-disorder just occurs.
Insomnia is one of common clinical disease, though being not belonging to critical illness, hinders people's normal life, work, study
And health, and can aggravate or induce palpitaition, the obstruction of qi in the chest, dizziness, headache, the illness such as apoplexy.Obstinate insomnia, brings to patient
Long-term pain, or even the dependence to sleeping medicine is formed, and long-term use of sleeping medicine can cause iatrogenic disease.
At present, clinically it is used for treating main selection hypnotic, Anshen Bunao mixture of insomnia etc..Hypnotic passes through maincenter
Calmness, suppresses the effect that corticocerebral excitability degree reaches hypnosis, and the effect of its treatment insomnia is preferable, but long-time service is pacified
Stator, can cause human body drug resistance and dependence, while have detrimental effect to liver kidney.Anshen Bunao mixture includes pilose antler, system, and what is first
The components such as crow, Herba Epimedii, rhizoma zingiberis, radix glycyrrhizae, jujube, vitamin B1, nourishing qi and blood, strong brain are calmed the nerves, for treating kidney essence deficiency, gas
Blood two loses the symptoms such as caused weak, forgetful, insomnia.For Anshen Bunao mixture compared with hypnotic, its side effect is smaller, but treats and lose
Dormancy slowly effect, the improvement for serious insomniac are smaller.
Therefore, it is necessary to develop a kind of material as natural, raw-food material, the nutrition food for improving sleep can be effectively relieved stress
Product, solve the deficiencies in the prior art.
The content of the invention
The defects of to overcome the prior art, the present invention provides one kind effectively to relieve stress, and improves sleep, natural, nontoxic
The prescription nutrition food of side effect.
The purpose of the present invention is realized by following technical solution:
A kind of effectively to relieve stress the nutritional food formula for improving sleep, the formula of the nutraceutical is by following material
Component forms by weight percentage:γ-aminobutyric acid 4.5-62.5.0%, tealeaves theanine 4.0-50.0%, casein water
Solve thing 3.0-35%, asparagus powder 10-25%, spiny jujuba seed powder 8-25%, L-calcium lactate 1.53-5.90%, vitamin B6
0.0007-0.0022% and sweetener 10-25%.
In order to further realize the present invention, the formula of the nutraceutical be by following material component by weight percentage
Composition:γ-aminobutyric acid 20%, tealeaves theanine 15%, casein hydrolysate 35%, asparagus powder 10%, spiny jujuba seed powder 8%,
L-calcium lactate 1.998%, vitamin B6 0.002% and sweetener 10%.
In order to further realize the present invention, the sweetener is white granulated sugar, one kind in antierythrite, isomaltose sugar alcohol
Or multiple combinations.
In order to further realize the present invention, the formulation of the nutraceutical is solid beverage.
A kind of preparation method for effectively relieving stress the nutraceutical for improving sleep, the preparation method bag of the solid beverage
Include following steps:
(1) sieve:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, Pfansteihl
Calcium, vitamin B6, sweetener cross 40 mesh sieve nets, spare;
(2) mix:It is sufficiently mixed uniformly, mixes 30 minutes in material input three-dimensional mixer after step (1) is sieved
Afterwards, you can carry out packaging finished product.
In order to further realize the present invention, the formulation of the nutraceutical is pressed candy.
A kind of preparation method for effectively relieving stress the nutraceutical for improving sleep, the preparation method bag of the pressed candy
Include following steps:
(1) sieve:Sweetener, spiny jujuba seed powder, γ-aminobutyric acid, tealeaves theanine are crossed into 40 mesh sieve nets, it is spare;
(2) pelletize:It is sufficiently mixed in material input granulator after step (1) is sieved;Added in mixed material
50% alcohol is sufficiently stirred;Mixed material is crossed into 12 mesh sieve nets again, and is controlled through oven drying, moisture in 3-5%;
(3) it is total mixed:By dried mixed material in step (2) and casein hydrolysate, L-calcium lactate, vitamin B6 point
Do not sieve, three-dimensional mixer is put into after sieving and is sufficiently mixed uniformly, incorporation time is 25-35 minutes, is made and treats tabletting
Particle;
(4) tabletting:Treat that the particle of tabletting is put into tablet press machine by obtained in step (3) and carry out tabletting, that is, tabletting is made
Candy finished product.
Further to realize the present invention, the formulation of the nutraceutical is beverage.
A kind of preparation method for effectively relieving stress the nutraceutical for improving sleep, the preparation method of the beverage include with
Lower step:
(1) prepare:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, Pfansteihl
Calcium, vitamin B6, sweetener are sufficiently mixed, and mixed material are made, then mixture thing and pure water are pressed 1:100 ratio is matched somebody with somebody
System, and stir to material and all dissolve, that is, mixing liquid is made;
(2) filter:Gained mixing liquid will be prepared in step (1) to be filtered by filter, that is, is made and is treated canned drink
Material;
(3) it is canned:Beverage after step (2) is filtered carries out canned, Zha Gai;
(4) sterilize:Gained beverage in step (3) is subjected to sterilization, packaging is finished product.
Beneficial effects of the present invention:
1) a kind of effectively relieve stress of the invention improves the prescription nutrition food slept and preparation method, by gamma-amino
Butyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, L-calcium lactate, vitamin, sweetener composition.Wherein,
γ-aminobutyric acid is distributed widely in animal and plant body, it is a kind of naturally occurring non-protein composition amino acid, can promote brain
Reactivity, brain tonic and intelligence development, promotes sleep, and beauty moisturizing, delays brain aging function, can supplement human body inhibitory neurotransmitter, tool
There are calmness, hypnosis, anticonvulsion, blood pressure lowering physiological action.The active amino acid of tealeaves theanine is L-thiamine, naturally occurring
Amino acid in green tea;Tealeaves theanine as a kind of relaxant, while promoting the mood to loosen without cause it is sleepy or
Other side effects, have and alleviate the effects such as tired pressure caused by overwork work, calmness, antianxiety, improvement sleep quality.Junket egg
The protein of white hydrolysate has sedation, can effectively be relieved stress by reducing blood pressure, reducing cortisol.Asparagus contains
The trace elements such as abundant vitamin B, vitamin A and folic acid, selenium, iron, manganese, zinc;Asparagus is with various necessary to human body
Amino acid, is a kind of natural food for being conducive to happy promotion sleep.Spina date seed, holds back gas and calms the nerves, and stomach fortune spleen, is medicine food
Homologous raw material, has the function that calm, hypnosis.L-calcium lactate is D-lactic acid calcium, is highly soluble in water, does not supplement needed by human body calcium
On the basis of matter, D-lactic acid can adjust microcirculation in human body.Vitamin 6 participates in amino acid metabolism in vivo, can turn amino acid
Become for an aminobutyric acid (GABA).GABA is the inhibitory transmitter of intracerebral nervous centralis, can promote to sleep.
2) a kind of effectively relieve stress of the invention improves the prescription nutrition food slept and preparation method, by gamma-amino
Butyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, L-calcium lactate, vitamin, sweetener composition.This hair
Bright prescription nutrition food selects raw-food material, and as raw material, natural, safe toxic side effect is smaller, is grown suitable for insomniac
Phase takes, and can effectively relieve stress, and improves sleep quality, is a kind of preferable health food.
3) effect for relieving stress, improving sleep of prescription nutrition food of the invention, can be obtained by Germicidal efficacy
Further confirm.
The insomniac of this experiment of 175 voluntary participations of selection, in 175 volunteers, 92 people of male, 83 people of women,
The age of volunteer is 25~62 years old, and the course of disease is 6~34 months.Wherein, the diagnostic criteria of insomniac is with reference to Chinese Spirit disease
Classification schemes《Chinese Spirit Obstacles classification and diagnostic criteria the 3rd edition (CCMD-3)》The diagnostic criteria of middle insomnia is formulated, this reality
Test and exclude the gestational period or women breast-feeding their children, mental patient, excessive drinking or downern misuser, with severe cardiac, brain, lung, kidney
Patient of systemic disease etc..
175 volunteers are randomly divided into 5 groups, every group of 35 people, be divided into control group, experimental group 1, experimental group 2, experimental group 3,
Experimental group 4.Wherein, control group take Jilin Aodong Yanbian Medicine Industry Co., Ltd production Anshen Bunao mixture, each 10ml,
3 times a day;Experimental group 1 takes pulvis prepared by the method for the embodiment of the present invention 1, and each 15ml, 3 times a day, warm water is taken after mixing it with water;It is real
Test group 2 and take pulvis prepared by the method for the embodiment of the present invention 2, each 15ml, 3 times a day, warm water is taken after mixing it with water;Experimental group 3 is taken
Pressed candy prepared by the method for the embodiment of the present invention 3,2 tablets once, 3 times a day;Experimental group 4 takes the embodiment of the present invention 4
Beverage prepared by method, one bottle every time, 2 times a day.Each group evaluates curative effect with 30 days as a treatment course after one course for the treatment of.
Efficacy assessment standard is divided into three grades, respectively effective, effective, invalid.Specifically, effective finger insomnia is bright
Aobvious to improve, sleep quality is higher;Effectively referring to insomnia improves, and sleep quality increases;Invalid finger insomnia is without improvement.
1. control group of table and contrast table the effect of experimental group 1, experimental group 2, experimental group 3 and experimental group 4
Group | It is effective | Effectively | It is invalid | It is efficient |
Control group | 6 | 9 | 20 | 42.9% |
Experimental group 1 | 9 | 13 | 13 | 62.9% |
Experimental group 2 | 12 | 14 | 9 | 74.3% |
Experimental group 3 | 8 | 17 | 10 | 71.4% |
Experimental group 4 | 13 | 16 | 6 | 82.3% |
Note:The total number of persons of effective percentage=(effective number+efficiently individual quantity)/group.
Statistical analysis is carried out to experimental data using statistic software SPSS, P < 0.05 are significant difference, have statistics
Meaning.From experimental result, prescription nutrition food of the invention improves the effect of sleep, improves higher than Anshen Bunao mixture and sleeps
Effect.And as shown in Table 1, the prescription nutrition food of the embodiment of the present invention 4 improves the best results of sleep, effective percentage is
82.3%.In this Germicidal efficacy, the index such as the blood pressure of volunteer, heart rate, hepatic and renal function does not occur in normal range (NR)
Bad toxicity.
Embodiment
With reference to the embodiment technical solution that the present invention is further explained.
Embodiment 1
The a kind of of the present invention effectively relieves stress the nutritional food formula for improving sleep, is mixed by the raw material of following parts by weight
Close the solid beverage being formulated:γ-aminobutyric acid 62.5%, tealeaves theanine 4.0%, casein hydrolysate 3.0%, asparagus
Powder 10.0%, spiny jujuba seed powder 8.0%, L-calcium lactate 1.53%, vitamin B6 0.0007% and white granulated sugar 10.9693%.
The preparation method of the nutraceutical solid beverage of the embodiment of the present invention 1 includes the following steps:
(1) sieve:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, Pfansteihl
Calcium, vitamin B6, white granulated sugar cross 40 mesh sieve nets, spare;
(2) mix:It is sufficiently mixed uniformly, mixes 30 minutes in material input three-dimensional mixer after step (1) is sieved
Afterwards, you can carry out packaging finished product.
Above-mentioned steps, are operated more than 300,000 grades in dust proof workshop, and at 16-24 DEG C, humid control exists temperature control
35-65%.Production and application tool device equipment is required to carry out disinfection using 75% alcohol before use.
Embodiment 2
The a kind of of the present invention effectively relieves stress the prescription nutrition food for improving sleep, is mixed by the raw material of following parts by weight
The solid beverage being formulated:γ-aminobutyric acid 4.25%, tealeaves theanine 9.8478%, casein hydrolysate 5%, asparagus
Powder 25%, spiny jujuba seed powder 25%, L-calcium lactate 5.9%, vitamin B6 0.0022% and antierythrite 25%.
The preparation method of the nutraceutical solid beverage of the embodiment of the present invention 2 includes the following steps:
(1) sieve:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, Pfansteihl
Calcium, vitamin B6, antierythrite cross 40 mesh sieve nets, spare;
(2) mix:It is sufficiently mixed uniformly, mixes 30 minutes in material input three-dimensional mixer after step (1) is sieved
Afterwards, you can carry out packaging finished product.
Above-mentioned steps, are operated more than 300,000 grades in dust proof workshop, and at 16-24 DEG C, humid control exists temperature control
35-65%.Production and application tool device equipment is required to carry out disinfection using 75% alcohol before use
Embodiment 3
The a kind of of the present invention effectively relieves stress the prescription nutrition food for improving sleep, is mixed by the raw material of following parts by weight
The pressed candy being formulated:γ-aminobutyric acid 8%, tealeaves theanine 50%, casein hydrolysate 6%, asparagus powder 15%,
Spiny jujuba seed powder 15.99%, L-calcium lactate 3%, vitamin B6 0.001% and isomaltose sugar alcohol 10%.
The preparation method of the nutraceutical pressed candy of the embodiment of the present invention 3 includes the following steps:
(1) sieve:Isomaltose sugar alcohol, spiny jujuba seed powder, γ-aminobutyric acid, tealeaves theanine are crossed into 40 mesh sieve nets, it is standby
With;
(2) pelletize:It is sufficiently mixed in material input granulator after step (1) is sieved;Added in mixed material
50% alcohol is sufficiently stirred so that material is in the light group of sticking into, i.e. scattered state of loosing one's grip;Mixed material is crossed into 12 mesh sieve nets again, and
Through oven drying, moisture is controlled in 3-5%;
(3) it is total mixed:By dried mixed material in step (2) and casein hydrolysate, L-calcium lactate, vitamin B6 point
Do not sieve, three-dimensional mixer is put into after sieving and is sufficiently mixed uniformly, incorporation time is 25-35 minutes, is made and treats tabletting
Particle;
(4) tabletting:Treat that the particle of tabletting is put into tablet press machine by obtained in step (3) and carry out tabletting, is i.e. finished product.
Above-mentioned steps, are operated more than 300,000 grades in dust proof workshop, and at 16-24 DEG C, humid control exists temperature control
35-65%.Production and application tool device equipment is required to carry out disinfection using 75% alcohol before use
Embodiment 4
The a kind of of the present invention effectively relieves stress the prescription nutrition food for improving sleep, is mixed by the raw material of following parts by weight
The beverage being formulated:γ-aminobutyric acid 20%, tealeaves theanine 15%, casein hydrolysate 35%, asparagus powder 10%, acid
Jujube kernel powder 8%, L-calcium lactate 1.998%, vitamin B6 0.002% and isomaltose sugar alcohol 10%.
The preparation method of the nutraceutical beverage of the embodiment of the present invention 4 includes the following steps:
(1) prepare:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, Pfansteihl
Calcium, vitamin B6, sweetener are sufficiently mixed, and mixed material are made, then mixture thing and pure water are pressed 1:100 ratio is matched somebody with somebody
System, and stir to material and all dissolve, that is, mixing liquid is made;
(2) filter:Gained mixing liquid will be prepared in step (1) to be filtered by filter, that is, is made and is treated canned drink
Material;
(3) it is canned:Beverage after step (2) is filtered carries out canned, Zha Gai;
(4) sterilize:Gained beverage in step (3) is subjected to sterilization, packaging is finished product.
Above-mentioned steps, are operated more than 300,000 grades in dust proof workshop, and at 16-24 DEG C, humid control exists temperature control
35-65%.Production and application tool device equipment is required to carry out disinfection using 75% alcohol before use
The foregoing is merely the better embodiment of the present invention, the invention is not limited in the above embodiment, is implementing
During there may be local small structural modification, if not departing from the essence of the present invention to the various changes or modifications of the present invention
God and scope, and belong within the scope of the claim and equivalent technologies of the present invention, then the present invention is also intended to comprising these changes
And modification.
Claims (9)
1. it is a kind of effectively relieve stress improve sleep prescription nutrition food, it is characterised in that the prescription nutrition food be by
Following material component forms by weight percentage:γ-aminobutyric acid 4.5-62.5.0%, tealeaves theanine 4.0-50.0%,
Casein hydrolysate 3.0-35%, asparagus powder 10-25%, spiny jujuba seed powder 8-25%, L-calcium lactate 1.53-5.90%, vitamin
B6 0.0007-0.0022% and sweetener 10-25%.
2. according to claim 1 effectively relieve stress the nutritional food formula for improving sleep, it is characterised in that described to match somebody with somebody
Square nutraceutical is made of by weight percentage following material component:γ-aminobutyric acid 20%, tealeaves theanine 15%,
Casein hydrolysate 35%, asparagus powder 10%, spiny jujuba seed powder 8%, L-calcium lactate 1.998%, vitamin B6 0.002% and sweet tea
Taste agent 10%.
3. according to claim 1 effectively relieve stress the prescription nutrition food for improving sleep, it is characterised in that the sweet tea
Taste agent is white granulated sugar, one or more combinations in antierythrite, isomaltose sugar alcohol.
4. effectively relieve stress the nutritional food formula for improving sleep, its feature according to claim 1-3 any one
It is, the formulation of the nutraceutical is solid beverage.
5. the preparation method according to claim 4 for effectively relieving stress the nutraceutical for improving sleep, it is characterised in that
The preparation method of the solid beverage comprises the following steps:
(1) sieve:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, L-calcium lactate, dimension
Raw element B6 and sweetener cross 40 mesh sieve nets, spare;
(2) mix:It is sufficiently mixed uniformly in material input three-dimensional mixer after step (1) is sieved, after mixing 30 minutes, i.e.,
It can carry out packaging finished product.
6. effectively relieve stress the prescription nutrition food for improving sleep, its feature according to claim 1-3 any one
It is, the formulation of the nutraceutical is pressed candy.
7. the preparation method according to claim 6 for effectively relieving stress the nutraceutical for improving sleep, it is characterised in that
The preparation method of the pressed candy comprises the following steps:
(1) sieve:Sweetener, spiny jujuba seed powder, γ-aminobutyric acid and tealeaves theanine are crossed into 40 mesh sieve nets, it is spare;
(2) pelletize:It is sufficiently mixed in material input granulator after step (1) is sieved;50% wine is added in mixed material
Essence is sufficiently stirred;Mixed material is crossed into 12 mesh sieve nets again, and is controlled through oven drying, moisture in 3-5%;
(3) it is total mixed:By dried mixed material in step (2) and casein hydrolysate, L-calcium lactate, vitamin B6 mistake respectively
Sieve, is put into three-dimensional mixer and is sufficiently mixed uniformly after sieving, incorporation time is 25-35 minutes, and the particle for treating tabletting is made;
(4) tabletting:Treat that the particle of tabletting is put into tablet press machine by obtained in step (3) and carry out tabletting, that is, pressed candy is made
Finished product.
8. effectively relieve stress the prescription nutrition food for improving sleep, its feature according to claim 1-3 any one
It is, the formulation of the nutraceutical is beverage.
9. the preparation method according to claim 8 for effectively relieving stress the nutraceutical for improving sleep, it is characterised in that
The preparation method of the beverage comprises the following steps:
(1) prepare:By γ-aminobutyric acid, tealeaves theanine, casein hydrolysate, asparagus powder, spiny jujuba seed powder, L-calcium lactate, dimension
Raw element B6 and sweetener are sufficiently mixed, and mixed material is made, then mixed material and pure water are prepared in 1: 100 ratio, and
Stirring is all dissolved to material, that is, mixing liquid is made;
(2) filter:Gained mixing liquid will be prepared in step (1) to be filtered by filter, that is, is made and is treated tinned drink;
(3) it is canned:Beverage after step (2) is filtered carries out canned, Zha Gai;
(4) sterilize:Gained beverage in step (3) is subjected to sterilization, that is, beverage product is made.
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
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CN109123301A (en) * | 2018-08-17 | 2019-01-04 | 秦皇岛长胜营养健康科技有限公司 | A kind of asparagus fermentation solid beverage and its preparation method and application |
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Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102266018A (en) * | 2011-08-22 | 2011-12-07 | 中国农业大学 | Preparation methods of asparagus whole meal and asparagus solid drink |
CN103222597A (en) * | 2013-04-28 | 2013-07-31 | 秦皇岛长胜农业科技发展有限公司 | Applications of instant asparagus powder in food, drugs and health food |
CN103519167A (en) * | 2013-10-08 | 2014-01-22 | 秦皇岛长胜农业科技发展有限公司 | Instant asparagus powder food with new applications of relieving pressure and improving memory |
CN103705836A (en) * | 2013-12-30 | 2014-04-09 | 广西梧州制药(集团)股份有限公司 | Traditional Chinese medicine composition for improving sleep and preparation method thereof |
CN103784611A (en) * | 2014-01-23 | 2014-05-14 | 云南白药天颐茶品有限公司 | Composition capable of improving sleep and relieving pressure and application thereof |
CN104146246A (en) * | 2014-07-17 | 2014-11-19 | 秦皇岛长胜营养健康科技有限公司 | Application of instant asparagus powder in food, medicine and healthcare product |
CN104256577A (en) * | 2014-07-24 | 2015-01-07 | 秦皇岛长胜营养健康科技有限公司 | New uses of instant asparagus powder for reducing dose of sleep medications or freeing insomniacs from sleep medications |
CN104940273A (en) * | 2015-07-21 | 2015-09-30 | 北京世纪合辉医药科技股份有限公司 | Vision improvement healthcare product and preparation method thereof |
CN104957561A (en) * | 2015-06-12 | 2015-10-07 | 徐伟东 | Sleep improving and pressure relieving composition and preparation thereof |
CN105146396A (en) * | 2015-10-21 | 2015-12-16 | 山东农业大学 | Processing method of asparagus powder |
CN107456531A (en) * | 2017-09-12 | 2017-12-12 | 江苏德和生物科技有限公司 | A kind of pharmaceutical composition, preparation and application that can improve sleep |
-
2017
- 2017-12-29 CN CN201711499496.1A patent/CN108030099A/en active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102266018A (en) * | 2011-08-22 | 2011-12-07 | 中国农业大学 | Preparation methods of asparagus whole meal and asparagus solid drink |
CN103222597A (en) * | 2013-04-28 | 2013-07-31 | 秦皇岛长胜农业科技发展有限公司 | Applications of instant asparagus powder in food, drugs and health food |
CN103519167A (en) * | 2013-10-08 | 2014-01-22 | 秦皇岛长胜农业科技发展有限公司 | Instant asparagus powder food with new applications of relieving pressure and improving memory |
CN103705836A (en) * | 2013-12-30 | 2014-04-09 | 广西梧州制药(集团)股份有限公司 | Traditional Chinese medicine composition for improving sleep and preparation method thereof |
CN103784611A (en) * | 2014-01-23 | 2014-05-14 | 云南白药天颐茶品有限公司 | Composition capable of improving sleep and relieving pressure and application thereof |
CN104146246A (en) * | 2014-07-17 | 2014-11-19 | 秦皇岛长胜营养健康科技有限公司 | Application of instant asparagus powder in food, medicine and healthcare product |
CN104256577A (en) * | 2014-07-24 | 2015-01-07 | 秦皇岛长胜营养健康科技有限公司 | New uses of instant asparagus powder for reducing dose of sleep medications or freeing insomniacs from sleep medications |
CN104957561A (en) * | 2015-06-12 | 2015-10-07 | 徐伟东 | Sleep improving and pressure relieving composition and preparation thereof |
CN104940273A (en) * | 2015-07-21 | 2015-09-30 | 北京世纪合辉医药科技股份有限公司 | Vision improvement healthcare product and preparation method thereof |
CN105146396A (en) * | 2015-10-21 | 2015-12-16 | 山东农业大学 | Processing method of asparagus powder |
CN107456531A (en) * | 2017-09-12 | 2017-12-12 | 江苏德和生物科技有限公司 | A kind of pharmaceutical composition, preparation and application that can improve sleep |
Non-Patent Citations (1)
Title |
---|
黄远英,等: "酪蛋白水解物与γ-氨基丁酸复配制剂改善睡眠功能的研究", 《食品安全质量检测学报》 * |
Cited By (21)
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---|---|---|---|---|
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CN109123301A (en) * | 2018-08-17 | 2019-01-04 | 秦皇岛长胜营养健康科技有限公司 | A kind of asparagus fermentation solid beverage and its preparation method and application |
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CN109380591A (en) * | 2018-11-29 | 2019-02-26 | 山东朱氏药业集团有限公司 | Gamma aminobutyric acid casein hydrolysate pressed candy and preparation method |
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