CN107997187A - With improvement skin elasticity and delay wrinkle systematic function composition and its application - Google Patents
With improvement skin elasticity and delay wrinkle systematic function composition and its application Download PDFInfo
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- CN107997187A CN107997187A CN201810109401.9A CN201810109401A CN107997187A CN 107997187 A CN107997187 A CN 107997187A CN 201810109401 A CN201810109401 A CN 201810109401A CN 107997187 A CN107997187 A CN 107997187A
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- -1 vitamin C Compound Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L19/00—Products from fruits or vegetables; Preparation or treatment thereof
- A23L19/01—Instant products; Powders; Flakes; Granules
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention belongs to food or health product technology field, and in particular to a kind of to have improvement skin elasticity, the composition for delaying wrinkle systematic function and its application.Said composition includes the raw material components of following parts by weight：70 80 parts of Isin glue collagen peptide, 15 parts of stripped tuna Elastin peptide, precious 15 parts of Rogor powder, 0.1 0.5 parts of vitamin C.In the present invention, collagen peptide Elastin peptide promotes fibroblast proliferation, so as to promote the synthesis of collagen and elastin laminin.Precious Rogor powder and vitamin C provide antioxidant content.The problems such as each component mutually cooperates with, and cutis laxa is dry, microgroove so as to improve, anti-aging, realizes the effect of beautifying skin, anti-ageing U.S. face.
Description
Technical field
The invention belongs to food or health product technology field, and in particular to one kind has improvement skin elasticity, delays wrinkle
The composition of systematic function and its application.
Background technology
Dermal cell is also gradually in flat, the ability of corium fabric mother cell synthesis collagenous fibres in the ageing process of skin
Decline, collagen content is gradually reduced.Intradermal elastic fibrosis, follows the string, and the elastic fibrous web of dermal papilla layer is reduced
Even disappear, this be skin aging cause wrinkle, relaxation and it is sagging the main reason for.Therefore, intradermal fibroblast is increased
Quantity, stimulate fibroblasts to secrete collagen could fundamentally solve the problems, such as aging face.
Skin synthesis collagen needs substantial amounts of hydroxyproline, and contains abundant hydroxyl dried meat ammonia in Isin glue collagen peptide
Acid.Oral small molecule Isin glue collagen peptide can substantially adjust skin moisture and grease balance, reduce the accumulation of metabolite.
Elastin laminin has stretching, extension and the elasticity shunk, and assigns injected organism tissue elasticity and tensile energy.Elastin laminin is in bullet
Content in property fiber be elastomer main component, synthesized and is secreted by the fibroblast of corium up to 90%.People
Body elastin mainly synthesizes early stage in late embryo stage to neonate, and adult life almost no longer has new elastin to produce.
Therefore, elastin laminin is supplemented for preventing that it is very significant that elastin deposition from following the string.
In addition to supplement is lost in collagen, it is also the eternal topic of skin makeup that it is anti-ageing, which to remove free radical,.
Vitamin C is known effective antioxidant, whitening composition.In addition, vitamin C also participates in skin synthesis collagen egg
White process.
Long wave ultraviolet（UVA）Skin fibroblasts can be caused with certain damage as the important component in solar radiation
Wound, causes lipid peroxidation, damaging cells film, reduces cell-proliferation activity.Precious Rogor powder can significantly improve D-galactolipin
Model mice serum and superoxide dismutase from liver（SOD）With the vigor of glutathione peroxidase, malonaldehyde is reduced
Content, is natural antioxidative food.
Found through retrieval, it is group not occur Isin glue collagen peptide, stripped tuna Elastin peptide, precious Rogor powder and vitamin C
Compound, therefore, the present invention are of great significance beautifying skin.
The content of the invention
It is an object of the invention to provide a kind of improvement skin elasticity being free from side effects, wrinkle systematic function is delayed to combine
Thing, said composition contain Isin glue collagen peptide, stripped tuna Elastin peptide, the precious component such as Rogor powder and vitamin C.
Collagen peptide can promote skin collagen and elastin laminin to synthesize, and elastin polypeptide has anti-oxidant work
Property and reducing power, precious Rogor powder can be obviously improved liver SOD activity, realize anti-oxidant, vitamin C has significant antioxygen
Change, whitening function.
The present invention adopts the following technical scheme that to achieve these goals：
One kind has improvement skin elasticity and delays wrinkle systematic function composition, and said composition includes the raw material of following parts by weight
Component：
70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 0.1-5 parts of Rogor powder, vitamin C 0.1-0.5
Part.
Further, the composition also contains additive, the additive selection fruits and vegetables concentrate, acid, sweet taste
The one or more of agent.
Further, one or more of the acid in citric acid, sodium citrate, malic acid；
The sweetener is a kind of or more in steviol glycoside, Aspartame, Sucralose, honey element, Fructus Momordicae fructoside
Kind；
Selected fruits and vegetables concentrate is selected from grapefruit inspissated juice, grapefruit concentration powder, apple juice concentrate, apple concentration powder, Cranberry concentration
Juice, Cranberry concentration powder, lemon inspissated juice, lemon concentration powder, beet inspissated juice either beet concentration powder in it is a kind of or more
Kind.
Further, when including the raw material components of following parts by weight for the situation of solid powder, said composition：
70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 0.1-5 parts of Rogor powder, vitamin C 0.1-0.5
Part, 5-10 parts of citric acid, 0.01-0.05 parts of sodium citrate, 0.01-0.05 parts of steviol glycoside, 0.01-0.05 parts of Sucralose,
5-10 parts of grapefruit Fruit powder, 5-10 parts of lemon Fruit powder, 5-10 parts of apple Fruit powder, 1-5 parts of sugar beet powder.
Further, when including the raw material components of following parts by weight for the situation of liquid, said composition：
320-350 parts of water, 70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 0.1-5 parts of Rogor powder, dimension life
Plain C 0.1-0.5 parts, 5-10 parts of citric acid, 0.01-0.05 parts of steviol glycoside, 0.01-0.05 parts of Sucralose, grapefruit Fruit powder
5-10 parts, 5-10 parts of lemon Fruit powder, 5-10 parts of apple Fruit powder.
Further, the formulation of said composition is liquid oral, pulvis, effervescent agent, tablet or granule formulation.
With improving skin elasticity and delaying the application of wrinkle systematic function composition, said composition is used to improve skin,
Anti-ageing crease-resistant preparation.
Beneficial effects of the present invention
In the present invention, collagen peptide Elastin peptide promotes fibroblast proliferation, so as to promote collagen and elastic egg
White synthesis.Precious Rogor powder and vitamin C provide antioxidant content.Each component mutually cooperates with, and is done so as to improve cutis laxa
The problems such as dry, microgroove, anti-aging, realize the effect of beautifying skin, anti-ageing U.S. face.
Brief description of the drawings
Fig. 1 is the preparation flow of composition solid pulvis provided by the invention；
Fig. 2 is the preparation flow of composition liquid beverage provided by the invention.
Embodiment
In order to better illustrate the present invention, technical scheme will be clearly and completely described.
Part I, having improves skin elasticity, the composition for delaying wrinkle systematic function and its application
Embodiment 1
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
80 parts of Isin glue collagen peptide, 5 parts of stripped tuna Elastin peptide, precious 5 parts of Rogor powder, 0.5 part of vitamin C.
In the present embodiment, Isin glue collagen peptide, extracts from fish-skin, fish scale, and molecular weight is 500-5000Da.Collagen
Commercially available product can also be used in peptide, such as Nitta Gelatin KK's collagen peptide can be used.Isin glue collagen peptide contains amino
Acid, dipeptides and tripeptides, have the characteristics that to be easy to absorption, no antigen, hypoallergenic, and have multiple biological activities, such as
Promote the growth and reparation, anti-oxidant etc. of skin, bone and cartilage.
In the present embodiment, stripped tuna Elastin peptide, extracts from stripped tuna heart arter ball, containing desmosine and isodensmosine, divides
Son amount 500-5000Da.Commercially available product can also be used in Elastin peptide, such as industry strain Co. Ltd. system elastin laminin can be used
Peptide.Stripped tuna Elastin peptide can promote fibroblast proliferation.
In the present embodiment, precious Rogor powder is the new raw-food material of 2017 approval publicities, has anti-oxidation efficacy.
Embodiment 2
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
70 parts of Isin glue collagen peptide, 1 part of stripped tuna Elastin peptide, precious 0.1 part of Rogor powder, 0.1 part of vitamin C.Remaining is the same as embodiment 1.
Embodiment 3
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
73 parts of Isin glue collagen peptide, 2 parts of stripped tuna Elastin peptide, precious 2 parts of Rogor powder, 0.2 part of vitamin C.Remaining is the same as embodiment 1.
Embodiment 4
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
76 parts of Isin glue collagen peptide, 3 parts of stripped tuna Elastin peptide, precious 3 parts of Rogor powder, 0.3 part of vitamin C.Remaining is the same as embodiment 1.
Embodiment 5
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
78 parts of Isin glue collagen peptide, 4 parts of stripped tuna Elastin peptide, precious 4 parts of Rogor powder, 0.4 part of vitamin C.Remaining is the same as embodiment 1.
Embodiment 6
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
80 parts of Isin glue collagen peptide, 5 parts of stripped tuna Elastin peptide, precious 5 parts of Rogor powder, 0.5 part of vitamin C, grapefruit Fruit powder 8
Part, 8 parts of lemon Fruit powder, 8 parts of apple Fruit powder, 4 parts of sugar beet powder, 7 parts of citric acid, 0.02 part of sodium citrate, Sucralose
0.01 part, 0.01 part of steviol glycoside.Remaining is the same as embodiment 1.
Embodiment 7
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
70 parts of Isin glue collagen peptide, 1 part of stripped tuna Elastin peptide, precious 0.1 part of Rogor powder, 0.1 part of vitamin C, grapefruit Fruit powder
5 parts, 5 parts of lemon Fruit powder, 5 parts of apple Fruit powder, 1 part of sugar beet powder, 5 parts of citric acid, 0.01 part of sodium citrate, Sucralose
0.01 part, 0.01 part of steviol glycoside.Remaining is the same as embodiment 1.
Embodiment 8
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
73 parts of Isin glue collagen peptide, 3 parts of stripped tuna Elastin peptide, precious 4 parts of Rogor powder, 0.4 part of vitamin C, grapefruit Fruit powder 6
Part, 6 parts of lemon Fruit powder, 6 parts of apple Fruit powder, 2 parts of sugar beet powder, 5 parts of citric acid, 0.01 part of sodium citrate, Sucralose
0.01 part, 0.01 part of steviol glycoside.Remaining is the same as embodiment 1.
Embodiment 9
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
76 parts of Isin glue collagen peptide, 4 parts of stripped tuna Elastin peptide, precious 3 parts of Rogor powder, 0.3 part of vitamin C, grapefruit Fruit powder 7
Part, 6 parts of lemon Fruit powder, 6 parts of apple Fruit powder, 3 parts of sugar beet powder, 5 parts of citric acid, 0.01 part of sodium citrate, Sucralose
0.01 part, 0.01 part of steviol glycoside.
Embodiment 10
A kind of to have the composition for improving skin elasticity, delaying wrinkle systematic function, said composition is made of following components by weight percent：
78 parts of Isin glue collagen peptide, 4 parts of stripped tuna Elastin peptide, precious 4 parts of Rogor powder, 0.4 part of vitamin C, grapefruit Fruit powder 7
Part, 7 parts of lemon Fruit powder, 7 parts of apple Fruit powder, 4 parts of sugar beet powder, 6 parts of citric acid, 0.01 part of sodium citrate, Sucralose
0.01 part, 0.01 part of steviol glycoside.
Embodiment, preparation method 1：Take appropriate Isin glue collagen peptide with vitamin C, precious Rogor powder, steviol glycoside by quality
Proportioning mixes, and adds stripped tuna elastin laminin, grapefruit Fruit powder, lemon Fruit powder and other auxiliary materials successively input mixing kettle,
Mixing 20 minutes, then through techniques such as filling, sterilizings, solid powder is made.
Embodiment, preparation method 2：Take appropriate raw material to mix, cross the filtering of 200 mesh, 65 DEG C ± 5 DEG C of preserving kettle's water temperature, adds
Enter Isin glue collagen peptide, compound Fruit powder, stir 15 minutes or so, detection product solid content, pH value, pol, then through filling
The techniques such as dress, sterilizing, cooling, are made liquid beverage.
The formulation of said composition is liquid oral, pulvis, effervescent agent, tablet or granule formulation.
With improving skin elasticity and delaying the application of wrinkle systematic function composition, said composition is used to improve skin,
Anti-ageing crease-resistant preparation.
Below by pharmacodynamic study result, the invention will be further described.
The anti-oxidant research of Part II treasured Rogor powder
Description of test：This research uses in vitro culture NIH/3T3 cells, uses long wave ultraviolet（UVA）Irradiation simulation damage,
Then observe after using precious Rogor powder, the SOD vigor of NIH/3T3 cells.By the vigor of SOD, precious Rogor is further studied
The oxidation resistance of powder.
Laboratory sample：
Precious Rogor powder is appropriate, NIH/3T3 cell lines.
Experimental method：
1. taking precious Rogor powder appropriate, 1 mg/mL is made into 0.1moL/L NaHCO3, it is 7.0 to adjust PH, filtration sterilization, packing
After be stored in -20 DEG C it is spare.
2. the NIH/3T3 cell line cell densities after recovery are adjusted to 1 × 10 ^6/mL or so, 3 are seeded to
A diameter of 100
In the culture dish of mm, per 5 mL of ware.No. 1 culture dish blank control group, without precious Rogor powder, No. 2 culture dishes are low dosage
（Precious Rogor powder 0.1mg/mL）, No. 3 culture dishes are high doses（Precious Rogor powder 100mg/mL）.
1. in addition to No. 1 culture dish, 2, No. 3 culture dishes are given 5.0 J/cm, 2 UVA and are irradiated 20 minutes.Continue to cultivate
After 24h, same with No. 1 culture dish, each group abandons supernatant, and cell is collected by centrifugation.The cell being collected into is cleaned 2 with 4 DEG C of PBS
Secondary, adding 0.5mL distilled waters makes it that uniformly cell liquid are transferred to cryopreservation tube, liquid nitrogen is directly placed into 5 seconds, is transferred to immediately
- 20 DEG C of refrigerators 30 seconds, further take out thaw at RT, so repeat 3 times, 1 × 10^ 7/mL cell pyrolysis liquids are made.Take
3 parts cracked of one formula of cell liquid, according to superoxide dismutase（SOD）Kit specification detects SOD vigor.
2. experimental result
4.1 experimental datas are represented with mean ± standard deviation, and with SPSS17.0 software statistics, comparison in difference is examined using t between each group
Proved recipe method, P ＜ 0.05 have statistical significance for difference.
4.2 mouse skin water content, concrete outcome are shown in Table 1
Table 1
| Group | SOD vigor（U/mL） |
| Blank control group（No. 1 culture dish） | 14.78±1.09 |
| Low dose group（No. 2 culture dishes） | 7.18±1.38* |
| High dose group（No. 3 culture dishes） | 13.45±0.82* |
Note：Compared with blank control group：* P ＜ 0.05.
Pharmacodynamic study of the Part III with improvement skin elasticity, the composition for delaying wrinkle systematic function
1. experimental animal
SPF grades of KM mouse, are randomly divided into 7 groups, every group 10, half male and half female：Normal group, model group, experimental group 1, experimental group 2,
Experimental group 3, experimental group 4, experimental group 5.
2. laboratory sample
Sample 1：According to the component and content of composition in embodiment 1, i.e. 80 parts of Isin glue collagen peptide, stripped tuna Elastin peptide 5
Part, precious 5 parts of Rogor powder, 0.5 part of vitamin C, 50ml solution is configured to normal saline solution.
Sample 2：According to the component and content of composition in embodiment 2, i.e. 70 parts of Isin glue collagen peptide, stripped tuna elastin laminin
1 part of peptide, precious 0.1 part of Rogor powder, 0.1 part of vitamin C, 50ml solution is configured to normal saline solution.
Sample 3：According to the component and content of composition in embodiment 3, i.e. 73 parts of Isin glue collagen peptide, stripped tuna elastin laminin
2 parts of peptide, precious 2 parts of Rogor powder, 0.2 part of vitamin C, 50ml solution is configured to normal saline solution.
Sample 4：According to the component and content of composition in embodiment 4, i.e. 76 parts of Isin glue collagen peptide, stripped tuna elastin laminin
3 parts of peptide, precious 3 parts of Rogor powder, 0.3 part of vitamin C, 50ml solution is configured to normal saline solution.
Sample 5：According to the component and content of composition in embodiment 5, i.e. 78 parts of Isin glue collagen peptide, stripped tuna elastin laminin
4 parts of peptide, precious 4 parts of Rogor powder, 0.4 part of vitamin C, 50ml solution is configured to normal saline solution.
3. experimental method：
The influence of mice aging model caused by 3.1 pairs of D- galactolipins
In addition to normal group, 5%D- galactolipin 1.0g/kg are subcutaneously injected in the daily nape of remaining 6 groups of mouse, normally organize daily nape skin
The isometric physiological saline of lower injection, continues modeling 40d.Modeling 11d starts, and in addition to normal group and model group, mouse, which is pressed, divides
Group situation according to dosage gavage daily, normal group and the model group then isometric physiological saline of daily gavage, continuous feeding 30d, place
Dead mouse, materials.Following index is detected：
1) moisture content of skin is measured.
2) hyaluronic acid contents in skin are measured：Using hyaluronic acid ELISA kit, illustrate in strict accordance with kit
Measure hyaluronic acid contents in skin.
3) skin elastase content is measured：Using elastin laminin ELISA kit, illustrate in strict accordance with kit
Measure skin elastase content.
In above-mentioned experiment, each experimental group modeling and gavage processing mode are shown in Table 2.
Table 2
| Modeling mode | Gavage reagent | |
| Normal group | Physiological saline（In equal volume） | Physiological saline 50ml/kg |
| Model group | 5%D- galactolipins 1g/kg | Physiological saline 50ml/kg |
| Experimental group 1 | 5%D- galactolipins 1g/kg | 1 50ml/kg of sample |
| Experimental group 2 | 5%D- galactolipins 1g/kg | 2 50ml/kg of sample |
| Experimental group 3 | 5%D- galactolipins 1g/kg | 3 50ml/kg of sample |
| Experimental group 4 | 5%D- galactolipins 1g/kg | 4 50ml/kg of sample |
| Experimental group 5 | 5%D- galactolipins 1g/kg | 5 50ml/kg of sample |
4. experimental result.
4.1 experimental datas represent that, with SPSS17.0 software statistics, comparison in difference is adopted between each group with mean ± standard deviation
With the t methods of inspection, P ＜ 0.05 have statistical significance for difference.
4.2 mouse skin water content, concrete outcome are shown in Table 3
Table 3
| Group number | Moisture content of skin（%） |
| Normal group | 62.32±1.03 |
| Model group | 41.25±1.04* |
| Experimental group 1 | 59.32±1.61# |
| Experimental group 2 | 45.76±1.11 |
| Experimental group 3 | 57.18±1.01# |
| Experimental group 4 | 54.28±1.31# |
| Experimental group 5 | 51.13±1.21# |
Note：Compared with normal group, * P ＜ 0.05；Compared with model group, #P ＜ 0.05
4.3 mouse skin hyaluronic acid contents, concrete outcome are shown in Table 4
Table 4
| Group number | Hyaluronic acid contents（μg/mg prot） |
| Normal group | 211±11 |
| Model group | 149±15* |
| Experimental group 1 | 209±12# |
| Experimental group 2 | 161±12# |
| Experimental group 3 | 194±11# |
| Experimental group 4 | 180±13# |
| Experimental group 5 | 174±16# |
Note：Compared with normal group, * P ＜ 0.05；Compared with model group, #P ＜ 0.05
4.4 mouse skin elastin laminin contents, concrete outcome are shown in Table 5
Table 5
| Group number | Elastin laminin content（μg/g） |
| Normal group | 779±14 |
| Model group | 463±11* |
| Experimental group 1 | 754±11# |
| Experimental group 2 | 568±12# |
| Experimental group 3 | 739±11# |
| Experimental group 4 | 711±13# |
| Experimental group 5 | 681±16# |
Note：Compared with normal group, * P ＜ 0.05；Compared with model group, #P ＜ 0.05
1. data above shows, precious Rogor powder can effectively lift SOD vigor, have antioxidation.
2. stripped tuna Elastin peptide, Isin glue collagen peptide, precious Rogor powder and ascorbic composition can be carried effectively
High moisture content of skin, hyaluronic acid contents and elastin laminin content, and the composition that ratio is appropriate, it is better.
Finally it should be noted that：Various embodiments above is merely to illustrate the technical method of the present invention, rather than its limitations.
Claims (7)
1. one kind, which has to improve, skin elasticity and delays wrinkle systematic function composition, it is characterised in that said composition include with
The raw material components of lower parts by weight：
70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 0.1-5 parts of Rogor powder, vitamin C 0.1-0.5
Part.
2. according to claim 1 have improvement skin elasticity and delay wrinkle systematic function composition, it is characterised in that：
The composition also contains additive, the additive selection fruits and vegetables concentrate, acid, sweetener it is a kind of or more
Kind.
3. according to claim 2 have improvement skin elasticity and delay wrinkle systematic function composition, it is characterised in that：
One or more of the acid in citric acid, sodium citrate, malic acid；
The sweetener is a kind of or more in steviol glycoside, Aspartame, Sucralose, honey element, Fructus Momordicae fructoside
Kind；
Selected fruits and vegetables concentrate is selected from grapefruit inspissated juice, grapefruit concentration powder, apple juice concentrate, apple concentration powder, Cranberry concentration
Juice, Cranberry concentration powder, lemon inspissated juice, lemon concentration powder, beet inspissated juice either beet concentration powder in it is a kind of or more
Kind.
4. according to claim 3 have improvement skin elasticity and delay wrinkle systematic function composition, it is characterised in that
When including the raw material components of following parts by weight for the situation of solid powder, said composition：
70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 0.1-5 parts of Rogor powder, vitamin C 0.1-0.5
Part, 5-10 parts of citric acid, 0.01-0.05 parts of sodium citrate, 0.01-0.05 parts of steviol glycoside, 0.01-0.05 parts of Sucralose,
5-10 parts of grapefruit Fruit powder, 5-10 parts of lemon Fruit powder, 5-10 parts of apple Fruit powder, 1-5 parts of sugar beet powder.
5. according to claim 3 have improvement skin elasticity and delay wrinkle systematic function composition, it is characterised in that
When including the raw material components of following parts by weight for the situation of liquid, said composition：
320-350 parts of water, 70-80 parts of Isin glue collagen peptide, 1-5 parts of stripped tuna Elastin peptide, precious 1-5 parts of Rogor powder, vitamin C
0.1-0.5 parts, 5-10 parts of citric acid, 0.01-0.05 parts of steviol glycoside, 0.01-0.05 parts of Sucralose, grapefruit Fruit powder 5-10
Part, 5-10 parts of lemon Fruit powder, 5-10 parts of apple Fruit powder.
6. having according to claim 1 to 5 is any improves skin elasticity and delays wrinkle systematic function composition, its feature
It is：The formulation of said composition is liquid oral, pulvis, effervescent agent, tablet or granule formulation.
7. any application for having improvement skin elasticity and delaying wrinkle systematic function composition of claim 1 to 6, it is special
Sign is：Said composition is used to improve skin, anti-ageing crease-resistant preparation.
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