CN109549216A - A kind of multiplexed protein anti-aging beauty-care composition, preparation method and application - Google Patents
A kind of multiplexed protein anti-aging beauty-care composition, preparation method and application Download PDFInfo
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- CN109549216A CN109549216A CN201811635070.9A CN201811635070A CN109549216A CN 109549216 A CN109549216 A CN 109549216A CN 201811635070 A CN201811635070 A CN 201811635070A CN 109549216 A CN109549216 A CN 109549216A
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- peptide
- collagen
- care composition
- aging
- aging beauty
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Engineering & Computer Science (AREA)
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Abstract
The present invention relates to food or health product technology fields, and in particular to arrives a kind of multiplexed protein anti-aging beauty-care composition, preparation method and application.The multiplexed protein anti-aging beauty-care composition prepares raw material in parts by weight, including multiplexed protein peptide 750~870, Elastin peptide 5~12.
Description
Technical field
The present invention relates to food or health product technology fields, and in particular to combines to a kind of multiplexed protein anti-aging beauty-care
Object, preparation method and application.
Background technique
Aging (also known as aging) increases, itself function after typically referring to biological development maturation at nominal conditions with the age
Decline, interior environment stabilizing power and stress ability decline, and the gradually retrogression of structure, component is deathward, irreversible existing
As.Aging be in a body inherent feature, while being an irreversible process again.Aging be life development must
So.Aging course is all embodied in whole, tissue, cell or even molecular level.Increase with the age, the essence of organ, tissue
Cell number, reaction sensibility and function gradually decline.
Anti-senescence function product currently on the market is broadly divided into external application and two classes for oral administration from use form.Topical class
Product is mainly used in the skin surface of aging, also can only respite face although can reach a period of time beautification of skin surface
The aging state of portion's skin cannot solve the problems, such as skin aging from the root；On the other hand, the emulsifier in externally applied product, perfume (or spice)
The chemical additives such as essence, pigment, preservative may also cause a degree of injury to consumer, and due safety is not achieved and wants
It asks.In contrast, existing class product for oral administration then stresses to solve the problems, such as aging in terms of removing free radical, and this kind of product also can
The beautification function of anti-aging is played to a certain extent, but is various because of the reason of leading to aging, therefore uses antioxygen
The substance of change effect can not achieve the purpose that synthesis is taken into account to improve body anti-senescence function.
In addition, also having collagen class product in existing class product for oral administration, but only mended with conventional I-type collagen
When filling, the big skin of molecular weight is more difficult first is absorbed into, the effect on skin be difficult embody generally require to take under normal circumstances it is more
Year is likely to certain effect；Secondly, only replenishing collagen without other compounding raw materials supports collagen, that skin
Skin still becomes loose, starts slack-off to skin blood circulation occur, subcutaneous tissue fat deposit also starts to become relaxation and owes
Elasticity is lacked, causes the tension between pore to reduce, so that situations such as pore is shown；But also it needs additionally to keep the skin wet and keeps flesh
Skin eubolism with it is tender.Therefore, it researches and develops a kind of various aspects to make overall plans, skin caused by improving aging of fundamentally starting with is dry
The symptoms such as dry, coarse, hyperplasia wrinkle, the comprehensive anti-aging ability for improving body, to reach quick beautifying and anti-aging effect
Product is necessary.
Summary of the invention
In order to solve the above-mentioned technical problem, the first aspect of the present invention provides a kind of anti-aging beauty-care composition, system
Standby raw material in parts by weight, including multiplexed protein peptide 750~870, Elastin peptide 5~12.
As a kind of perferred technical scheme, raw material is prepared in parts by weight, including multiplexed protein peptide 780~820, bullet
Property protein peptides 7~10.
As a kind of perferred technical scheme, the multiplexed protein peptide includes that I-type collagen peptide, typeⅡ Collagen are low
Poly- peptide and III collagen type peptide.
As a kind of perferred technical scheme, the multiplexed protein peptide is grouped as by the group of following parts by weight: type i collagen egg
White peptide 700~750, typeⅡ Collagen oligopeptide 60~90 and III collagen type peptide 20~50.
As a kind of perferred technical scheme, the hyalomitome containing 3~8wt% in the typeⅡ Collagen oligopeptide
Acid.
As a kind of perferred technical scheme, the sulfuric acid containing 25~30wt% is soft in the typeⅡ Collagen oligopeptide
Ossein.
As a kind of perferred technical scheme, the Elastin peptide is stripped tuna Elastin peptide.
As a kind of perferred technical scheme, preparing raw material further includes auxiliary material；The auxiliary material includes VC.
The second aspect of the invention provides the preparation method of anti-aging beauty-care composition as described above, will prepare raw material
It is added in purified water and is stirred according to the proportion, then by microwave sterilization to obtain the final product.
The third aspect of the invention provides a kind of anti-aging beauty-care product, and it includes as described above anti-for preparing raw material
Aging cosmetic composition.
As a kind of perferred technical scheme, the dosage form of the anti-aging beauty-care product is oral liquid dosage forms.
The utility model has the advantages that anti-aging beauty-care composition provided by the invention and product can make the plentiful high resilience of skin, profit
Sliding cuticula, stimulates skin microcirculation, boosts metabolism, the skin of structural relaxation is made to become compact, smooth, glossy.Short
The wrinkle quantity on skin of face is reduced in time, is improved skin surface situation, prevention and the generation for improving deep wrinkle, is made skin
What is become is smooth compact.It is combined by the golden ratio between multiplexed protein peptide and Elastin peptide, promotes each component by human body
Skin Cell is propped up in the absorption of middle related skin tissue, in conjunction with moisturizing and inhibits the effect of wrinkle, is reached jointly and is unfolded coarse groove, light
Change microgroove, delay skin aging.These components are filled between dermis of skin after being absorbed by linked groups simultaneously, and it is tight to increase skin
Density generates skin tension, reduces pore, keeps skin tight and high resilience.Moreover, said components synergistic effect it
Under, increase the water conservation water lock ability of skin histology, keeps skin water profit glossy, distribute the brilliance of health.In addition, provided by the invention
Anti-aging beauty-care composition and product provide fortification each tissue organ function for tissue, promote body immunity.Together
When can improve anxiety, wakefulness state, treat neurasthenia, improve endocrine, prevent aging etc..
Detailed description of the invention
In order to illustrate more clearly of the technical solution in the present invention, attached drawing needed in the embodiment will be made below
Simply introduce, it should be apparent that, drawings in the following description are only some embodiments of the invention, common for this field
For technical staff, without creative efforts, it is also possible to obtain other drawings based on these drawings.
Fig. 1 is face wrinkles situation map of the subject before the anti-aging beauty-care product provided using the embodiment of the present invention 5.
Fig. 2 is face wrinkles feelings of the above-mentioned subject after the anti-aging beauty-care product provided using the embodiment of the present invention 5
Condition figure.
Specific embodiment
It is further clear, complete that the technical characteristic work in technical solution is provided to the present invention With reference to embodiment
Description, unless otherwise defined, all technologies used herein and scientific term have and the common skill of fields of the present invention
The normally understood identical meaning of art personnel.When there is a conflict, the definition in this specification shall prevail.
Word " preferred ", " preferably ", " preferred " in the present invention etc. refer to, can provide certain in some cases
The embodiment of the present invention of a little beneficial effects.However, other embodiments may also under identical circumstances or in the case of other
It is preferred.In addition, not implying that other embodiments are unavailable to the statement of one or more preferred embodiments, it is not yet
It is intended to exclude other embodiments except the scope of the present invention.
Term "comprising" used herein, " comprising ", " having ", " containing " or its any other deformation, it is intended that covering
Non-exclusionism includes.For example, composition, step, method, product or device comprising listed elements are not necessarily limited to those and want
Element, but may include not expressly listed other elements or such composition, step, method, product or device it is intrinsic
Element.
In addition, indefinite article "an" before element of the present invention or component and "one" quantitative requirement to element or component
(i.e. frequency of occurrence) unrestriction.Therefore "one" or "an" should be read as including one or at least one, and odd number
The element or component of form also include plural form, unless the obvious purport of the quantity refers to singular.
In order to solve the above-mentioned technical problem, the first aspect of the present invention provides a kind of anti-aging beauty-care composition, system
Standby raw material in parts by weight, including multiplexed protein peptide 750~870, Elastin peptide 5~12；Preferably, raw material is prepared with weight
Measure part meter, including multiplexed protein peptide 780~820, Elastin peptide 7~10；It is further preferred that it prepares raw material with parts by weight
Meter, including multiplexed protein peptide 800, Elastin peptide 8.
Multiplexed protein peptide in the present invention is the mixture of a variety of collagen peptides, can change collagen or gelatin etc.
Furthermore property collagen is also possible to artificial synthesized as the collagen peptide as obtained from hydrolysis process such as enzyme, acid, alkali etc.
Collagen peptide.As collagen, gelatin, the animal such as from ox, pig, chicken or the collagen egg from fish can be used
White, gelatin, the especially connective tissue from the skin of animal, bone and tendon etc., fish-skin, the collagen albumen that fish scale extracts
Matter.It is preferable to use the collagens that fish-skin, fish heart arter etc. obtain in the present invention.
In some preferred embodiments, the multiplexed protein peptide includes that I-type collagen peptide, typeⅡ Collagen are low
Poly- peptide and III collagen type peptide；Preferably, the multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen
Peptide 700~750, typeⅡ Collagen oligopeptide 60~90 and III collagen type peptide 20~50；It is further preferred that described more
Weight protein peptides are grouped as by the group of following parts by weight: I-type collagen peptide 710, typeⅡ Collagen oligopeptide 70 and III type glue
Former protein peptides 30.
I-type collagen peptide, typeⅡ Collagen oligopeptide and III collagen type peptide are by its function in the present invention
The collagen peptide that feature is classified is collagen peptide type well-known to those skilled in the art.Wherein type i collagen egg
White peptide and III collagen type oligopeptide are source of animal protein, and the collagen peptide from fish-skin, the protein peptides are without sugar
And fat, heat are low.In the present invention, preferable weight-average molecular weight is the polypeptide of 2000 dalton.Type i collagen in the present invention
Protein peptides and III collagen type oligopeptide can extract to obtain by means such as protein in hydrolytic fish skin, hydrolyzed glue
The aqueous solution of former protein peptides can be used directly, used after can also being handled by drying, abrasive flour etc..It is further excellent
Choosing, I-type collagen peptide and III collagen type oligopeptide are ground, using the microparticle of 35~45 mesh.Described II
Collagen type oligopeptide is ocean fish cartilage hydrolysate.By above-mentioned three kinds of collagen peptide particles (or powder) according to above-mentioned heavy
Amount ratio mixes up to the multiplexed protein peptide.Certainly, the I-type collagen peptide in the present invention, typeⅡ Collagen oligopeptide
It can be obtained from purchase on the market with III collagen type peptide, such as the Related product of ABYSS company, France.
It is found by the applicant that using the collagen peptide compounded combination of above-mentioned three types at multiplexed protein peptide in use, not having to
It can be easily absorbed by the body by the excessive decomposition of the excessive decomposition of internal large intestine, and its absorption does not need to absorb greatly
The energy of amount is directly entered blood circulation after being absorbed by the complete form of internal duodenum, particular energy therein is conveyed
To corporal parts, soak time is fast.Furthermore it is to skin histology after above-mentioned multiplexed protein peptide is combined with Elastin peptide
Permeability enhancing, can with skin base layer cell combination, participate in and improve Skin Cell metabolism, make the collagen egg in skin
White activity is reinforced, and cell Proliferation and differentiation is made to become faster, constantly generation neoblast, and reaches through basal layer, spinous layer, stratum granulosum etc.
The cuticula of skin supplements enough collagens for it, and keeps the integrality of cuticula fibre structure, improves Skin Cell
Living environment and the metabolism for promoting skin histology enhance blood circulation, to slow down the aging rate of skin.In addition, Shen
It asks someone unexpected discovery, when the ratio in one present invention of multiplexed protein peptide and Elastin peptide is used in compounding, skin
Tight degree, the reduction degree of wrinkle quantity and other effects highly significant.It may be to be cooperateed with due to multiplexed protein peptide with Elastin peptide
Effect, while supplementing skin collagen, additionally it is possible to be filled between dermis of skin, increase its tightness and elasticity, make
Skin generates certain tension, reduces pore, avoids the relaxation of skin, while reducing the wrinkle on skin.
In some preferred embodiments, the hyalomitome containing 3~8wt% in the typeⅡ Collagen oligopeptide
Acid；Preferably, the hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide.
Hyaluronic acid in the present invention is dissacharide units sodium hyaluronate, is made of D-Glucose aldehydic acid and N-acetyl-glucosamine
, also known as uronic acid, basic structure are made of large-scale more two dissacharide units D-Glucose aldehydic acid and N-acetyl-glucosamine
Carbohydrate.Hyaluronic acid contents in the present invention can be measured by absorbance method, can specifically be carried out as follows: point
The hyaluronic acid standard working solution of a certain amount of (100 μ g/ml) is not added in 20ml colorimetric cylinder, 12ml Alcian blue dyes are added
Solution is diluted to scale, as standard sample liquid pipe；Water another plus with hyaluronic acid titer same volume, is added 12ml A Lixin
Blue dye solution, is diluted to scale, as colour reagent pipe；Another plus with hyaluronic acid standard working solution same volume water again, adds
The 0.5mol/L sodium acetate solution for entering 12ml, is diluted to scale, as reference solution pipe.Above-mentioned three kinds of solution is at 25 ± 1 DEG C
Under the conditions of after constant temperature 10min, at optimal absorption wavelength 480nm, its absorbance is surveyed with 2cm cuvette, to calculate transparent
Matter acid content, remaining concrete operations are operated according to conventional method well-known to those skilled in the art.
In some preferred embodiments, the sulfuric acid containing 25~30wt% is soft in the typeⅡ Collagen oligopeptide
Ossein；Preferably, the chondroitin sulfate containing 27wt% in the typeⅡ Collagen oligopeptide.
In some preferred embodiments, the hydroxyl dried meat ammonia in the typeⅡ Collagen oligopeptide containing 3~6wt%
Acid；Preferably, the hydroxyproline containing 5wt% in the typeⅡ Collagen oligopeptide.
Chondroitin sulfate in the present invention is to be covalently attached a kind of glycosaminoglycan that proteoglycans is formed on protein.Sulphur
Aching and limp ossein is distributed widely in the extracellular matrix and cell surface of animal tissue, and sugar chain is by alternate glucuronic acid and N- second
Acyl galactosamine (also known as N- acetylamino galactosamine) disaccharide unit composition is connected to core protein like sugared link zone by one
Serine residue on.The cartilage of ocean fish can be taken out, repeatedly be disappeared under the conditions of certain density acetic acid through pepsin
Change, is centrifugated certain time at certain temperature and revolving speed, finally carries out ion exchange with DEAE-Sephadex A-50
Chromatography, dialysis, then saltoutd with NaCl, the typeⅡ Collagen oligopeptide purified.Can by adjust acid concentration, digestion and
Hydrolysis time, temperature, the conditions such as selection of amberplex regulate and control chondroitin sulfate, hydroxyl in typeⅡ Collagen oligopeptide
The content of the components such as proline, hyaluronic acid.
It is found by the applicant that adjusting containing for chondroitin sulfate in typeⅡ Collagen oligopeptide, hydroxyproline and hyaluronic acid
Amount, with the other components synergistic effect such as Elastin peptide, other types of collagen peptide under can accelerate human body to this
The absorption of composition shortens composition to the onset time of skin anti-aging, reduces the wrinkle on skin in a short time, hence it is evident that
Improve skin aging speed on the face.
In the present invention chondroitin sulfate described in typeⅡ Collagen oligopeptide can by conventional test method into
Row test, such as carbazole spectrophotometry, specific chondroitin sulfate hydrolyze in an acidic solution generate D-Glucose aldehydic acid with
N- acetyl-D-amino galactolipin, this method are the glucose that equimolar number is generated based on heating hydrolysis in chondroitin sulfate solution
Aldehydic acid occurs condensation reaction with carbazole solution and generates aubergine compound.Wherein the glucuronic acid in chondroitin sulfate is full
Furfural is generated with heating under the action of boric acid solution and sodium tetraborate sulfuric acid solution, is added in 0.2% carbazole ethanol solution
The aobvious red of heat, has absorption maximum in 520nm wavelength, containing for chondroitin sulfate can be calculated in the absorbance for testing the wavelength
Amount.The hydroxyproline described in typeⅡ Collagen oligopeptide can be according to standard GB/T/T 9695.23- in the present invention
The method recorded on 2008 " meat is measured with meat products hydroxyproline content " is measured.
In some preferred embodiments, the Elastin peptide is stripped tuna Elastin peptide.
Heretofore described Elastin peptide is the main component of elastomer in rawhide tissue, and peptide chain contains multiple ammonia
Base acid residue.Different from collagen and keratin, there is no through the continuous of entire peptide chain in the amino acid sequence of Elastin peptide
Repeated periodic structure, but be alternately arranged and constituted by the short catenin peptide fragment of two types.One kind is hydrophobic short catenin peptide
Molecule is assigned with elasticity；Another short catenin peptide is the α spiral of rich alanine and lysine residue, is responsible between adjacent molecule
Form crosslinking.After composition product is previously used, wherein the Elastin peptide with cross-linked structure with multiplexed protein
Under the components such as peptide synergistic effect, make keratoderma that there is certain elasticity by changing its conformation.
Stripped tuna Elastin peptide is preferably used in the present invention.The stripped tuna Elastin peptide is to extract from stripped tuna heart arter
A kind of protein peptides, contain a large amount of desmosine and isodensmosine.Stripped tuna Elastin peptide in the present invention can be from the market
It is commercially available, such as the Related product of ABYSS company, France.It can also be prepared by voluntarily extracting, mainly by as follows
Step: 1) cutting off the bulbus arteriosus that stripped tuna is connected to cardia, is immersed in heat treatment in lye and isolates albumen therein
Stripped tuna Elastin peptide can be obtained using oxidation enzymatic treatment, deodorization, Purification by filtration, drying and other steps in matter.
In some preferred embodiments, preparing raw material further includes auxiliary material；The auxiliary material includes VC.
The structure of VC (vitamin C) is a kind of polyol similar to glucose, the 2nd and the 3rd upper two in molecule
A adjacent enolic hydroxyl easily dissociates and releases H+, therefore there is the property of acid, also known as ascorbic acid.To VC's in the present invention
Content does not carry out particular determination, and dosage is not influencing the original related anti-aging performance of the composition and is being prepared
It can according to need and be adjusted under the premise of the performances such as product mouthfeel.
It is found by the applicant that in the present invention above-mentioned three types collagen peptide with specific weight ratio compounded combination at
The composition that is compounded with the weight ratio of about 800:8 of multiplexed protein peptide and Elastin peptide in addition to can be by human body
All kinds of collagens needed for quickly absorbing supplement skin, and certain support is provided for skin, it is not loose to make it have elasticity
While relaxation, the also unexpected discovery of applicant, moreover it is possible to bright first hairdressing, improvement sleep and constipation, quickening to a certain extent
The resume speed of ligament injury etc..
The second aspect of the invention provides the preparation method of anti-aging beauty-care composition as described above, will prepare raw material
It is added in purified water and is stirred according to the proportion, then by microwave sterilization to obtain the final product.
The third aspect of the invention provides a kind of anti-aging beauty-care product, and it includes as described above anti-for preparing raw material
Aging cosmetic composition.
In some preferred embodiments, the dosage form of the anti-aging beauty-care product is oral liquid dosage forms.
The anti-aging beauty-care product in the present invention can conventionally be prepared, specifically can will be in composition
After each component is sufficiently mixed, pure water (using pharmaceutical grade purified water, meet in pharmacopeia to water for pharmaceutical purposes standard) is added,
Can heating appropriate dispersion obtain stable liquid.
The present invention is specifically described below by embodiment.It is necessarily pointed out that following embodiment is only used
In the invention will be further described, it should not be understood as limiting the scope of the invention, professional and technical personnel in the field
The some nonessential modifications and adaptations made according to the content of aforementioned present invention, still fall within protection scope of the present invention.
In addition, if without other explanations, it is raw materials used to be all commercially available.
Embodiment
Embodiment 1
Embodiment 1 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
750, Elastin peptide 5 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
700, typeⅡ Collagen oligopeptide 60 and III collagen type peptide 20；Contain 3wt% in the typeⅡ Collagen oligopeptide
Hyaluronic acid, 25wt% chondroitin sulfate and 3wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, and component each in composition is filled
After dividing mixing, pure water (using pharmaceutical grade purified water, meet in pharmacopeia to water for pharmaceutical purposes standard) is added, is dispersed with stirring mixed
Conjunction obtains stable liquid to obtain the final product.
Embodiment 2
Embodiment 2 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
870, Elastin peptide 12 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen
Peptide 750, typeⅡ Collagen oligopeptide 90 and III collagen type peptide 50；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 8wt%, the chondroitin sulfate of 30wt% and 6wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Embodiment 3
Embodiment 3 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
780, Elastin peptide 7 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain 3wt% in the typeⅡ Collagen oligopeptide
Hyaluronic acid, 25wt% chondroitin sulfate and 3wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Embodiment 4
Embodiment 4 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
820, Elastin peptide 10 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen
Peptide 710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 8wt%, the chondroitin sulfate of 30wt% and 6wt% hydroxyproline.
Hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide, 27wt% chondroitin sulfate and
5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Embodiment 5
Embodiment 5 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 4.5wt%, the chondroitin sulfate of 27wt% and 5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 1
Comparative example 1 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide 710, II Collagen Type VI
Albumen oligopeptide 70 and III collagen type peptide 30；Hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide,
The chondroitin sulfate and 5wt% hydroxyproline of 27wt%.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 2
Comparative example 2 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: typeⅡ Collagen
Oligopeptide 70 and III collagen type peptide 30；Hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide,
The chondroitin sulfate and 5wt% hydroxyproline of 27wt%.
The III collagen type peptide is purchased from Luo Sailuo company, France；TypeⅡ Collagen oligopeptide is purchased from France ABYSS
The Related product of company；The Elastin peptide is purchased from the stripped tuna elastin laminin peptide product of Japanese garment or robe made of feathers food.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 3
Comparative example 3 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710 and III collagen type peptide 30；Hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide, 27wt%
Chondroitin sulfate and 5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；The Elastin peptide
Stripped tuna elastin laminin peptide product purchased from Japanese garment or robe made of feathers food.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 4
Comparative example 4 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710 and typeⅡ Collagen oligopeptide 70；Hyaluronic acid containing 4.5wt% in the typeⅡ Collagen oligopeptide,
The chondroitin sulfate and 5wt% hydroxyproline of 27wt%.
The I-type collagen peptide is purchased from Luo Sailuo company, France；TypeⅡ Collagen oligopeptide is public purchased from France ABYSS
The Related product of department；The Elastin peptide is purchased from the stripped tuna elastin laminin peptide product of Japanese garment or robe made of feathers food.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 5
Comparative example 5 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain 27wt% in the typeⅡ Collagen oligopeptide
Chondroitin sulfate and 5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 6
Comparative example 6 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 4.5wt% and the chondroitin sulfate of 27wt%.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 7
Comparative example 7 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
800, Elastin peptide 8 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen peptide
710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 4.5wt%, the chondroitin sulfate of 5wt% and 5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Comparative example 8
Comparative example 8 provides a kind of anti-aging beauty-care composition, prepares raw material in parts by weight, including multiplexed protein peptide
1000, Elastin peptide 5 and vitamin C 3；The multiplexed protein peptide is grouped as by the group of following parts by weight: I-type collagen
Peptide 710, typeⅡ Collagen oligopeptide 70 and III collagen type peptide 30；Contain in the typeⅡ Collagen oligopeptide
The hyaluronic acid of 4.5wt%, the chondroitin sulfate of 27wt% and 5wt% hydroxyproline.
The I-type collagen peptide and III collagen type peptide are purchased from French Luo Sailuo company；TypeⅡ Collagen is low
Poly- peptide is purchased from the Related product of ABYSS company, France；The Elastin peptide is purchased from the stripped tuna elastin laminin of Japanese garment or robe made of feathers food
Peptide product.
This example additionally provides the anti-aging beauty-care product being prepared by above-mentioned composition, preparation method and embodiment 1
It is identical.
Performance test
1, randomly select 390 women's health subjects, average age 37 years old (28~55 years old), in this test it is all by
Examination person's recipient site skin health is without exception, and facial recipient site is without obvious hair；Subject signs informed consent form
After take one's test, and subject every morning 10~11 point and takes between 5~6 same amount of at night during testing
The product, wherein to 5~10 people similar situations such as daily schedule, age during each case selection as test pair
As by three-dimensional test method (In vivo method) test subject in the anti-aging provided using the embodiment of the present invention and comparative example
Specific region wrinkle area (%) and wrinkle volume (mm on 6 weeks its skin of face of front and back of beauty product3), it is indicated with x/y, wherein
X be before use, y is to calculate its average value as test result using rear, it is crease-resistant to characterize product provided by the invention with this
Line, the quality for acting on skin smooth.
2, after allowing above-mentioned selection to clean face with clear water as the subject of anti-wrinkle test object, in constant temperature and humidity (25
± 1 DEG C and 50 ± 5%) it waits in environment 45 minutes, skin then is carried out using Corneometer and DermaLab to its face
Water content (%) test, each subject's duplicate measurements 5 this, each product subject be 5~8 people, take its average value make
For test result.
1 performance test table of table
Anti-aging beauty-care composition and product provided in an embodiment of the present invention have extraordinary anti-as can be seen from the above table
Wrinkle effect reduces the wrinkle quantity on skin of face in a short time, improves skin surface situation, prevention and improvement deep wrinkle
Generation, make skin become it is smooth compact.In addition, the water content of skin be also significantly greater than the composition that other comparative examples provide and
Product (note: the test cutin layer depth in the closely related present invention of the parameters such as specific water content and test cutin layer depth of skin
Degree is 15~40 μm).In addition, in conjunction with Figure of description, it can be seen that subject provided using the embodiment of the present invention 5 it is anti-ageing
The wrinkle quantity of its face significantly reduces after old beauty product, and wrinkle depth shoals, it will be seen that anti-aging beauty-care provided by the invention
Composition and product have excellent anti-aging performance.
3, allow above-mentioned 390 subjects (corresponding 30 people of each case) from the following aspect to the embodiment of the present invention and comparative example
The experience of the anti-aging beauty-care product of offer is evaluated, and from following 5 angle skin tightness, improves sleep, brighten the hair, hair
Regeneration, improvement stomach, improvement immunity are evaluated.Wherein the compact degree of facial skin can be from the thicker big degree of pore, if
It changes significantly in flexible superior surface and is angularly evaluated；Improve whether stomach mainly has digestion to ask after taking the product
Whether topic there is constipation and angularly evaluates；Improve immunity mainly from whether facilitate wound healing (including sports type wound,
Such as ligament injury).Wherein to be obviously improved, some improve, without significant changes, cause uncomfortable sequence slash to separate to indicate
Corresponding number.
2 sensory evaluation of table
As can be seen from the above table, anti-aging beauty-care composition and product provided in an embodiment of the present invention have extraordinary comprehensive
Effect is closed, skin can be made full of elastic, moist, fine and smooth, smooth to support skin as bracket；It is provided for subcutaneous tissue of scalp
Enough nutriment to regenerate, nutrition hair, keep impaired hair soft bright moving, at the same collagen have moisture retention, more make
Healthy hair is full of elasticity；Sleep can also be covered simultaneously, improves immunity, improve stomach, not constipation, and facilitates wound healing,
Such as the beneficial effects such as ligament injury.
The above described is only a preferred embodiment of the present invention, be not the limitation for making other forms to invention, it is any
Those skilled in the art are changed or are changed to the equivalent of equivalent variations possibly also with the technology contents of the disclosure above
Embodiment, but without departing from the technical solutions of the present invention, above embodiments are made according to the technical essence of the invention
Any simple modification, equivalent variations and remodeling, still fall within the protection scope of technical solution of the present invention.
Claims (10)
1. a kind of anti-aging beauty-care composition, which is characterized in that it prepares raw material in parts by weight, including multiplexed protein peptide 750
~870, Elastin peptide 5~12.
2. anti-aging beauty-care composition as described in claim 1, which is characterized in that it prepares raw material in parts by weight, including
Multiplexed protein peptide 780~820, Elastin peptide 7~10.
3. anti-aging beauty-care composition as described in claim 1, which is characterized in that the multiplexed protein peptide includes type i collagen
Protein peptides, typeⅡ Collagen oligopeptide and III collagen type peptide.
4. anti-aging beauty-care composition as claimed in claim 3, which is characterized in that the multiplexed protein peptide is by following parts by weight
Group be grouped as: I-type collagen peptide 700~750, typeⅡ Collagen oligopeptide 60~90 and III collagen type peptide 20~
50。
5. anti-aging beauty-care composition as claimed in claim 4, which is characterized in that contain in the typeⅡ Collagen oligopeptide
There is the hyaluronic acid of 3~8wt%.
6. anti-aging beauty-care composition as claimed in claim 5, which is characterized in that contain in the typeⅡ Collagen oligopeptide
There is the chondroitin sulfate of 25~30wt%.
7. anti-aging beauty-care composition as described in claim 1, which is characterized in that the Elastin peptide is stripped tuna elasticity egg
White peptide.
8. anti-aging beauty-care composition as described in claim 1, which is characterized in that it further includes auxiliary material that it, which prepares raw material,；It is described
Auxiliary material includes VC.
9. the preparation method of the anti-aging beauty-care composition as described in claim 1~8 any one, which is characterized in that will make
Standby raw material is added in purified water according to the proportion to be stirred, then by microwave sterilization to obtain the final product.
10. a kind of anti-aging beauty-care product, which is characterized in that it includes as described in claim 1~8 any one that it, which prepares raw material,
Anti-aging beauty-care composition.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111418748A (en) * | 2020-05-22 | 2020-07-17 | 武汉华嫩科技有限公司 | Elastic and collagen double-protein peptide beverage and preparation method thereof |
| CN113663051A (en) * | 2020-04-30 | 2021-11-19 | 广西嘉盈生物科技有限公司 | Composition of skipjack elastin peptide and collagen oligopeptide and preparation method thereof |
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| SG190342A1 (en) * | 2010-11-30 | 2013-06-28 | Amorepacific Corp | Cosmetic composition for whitening and improving the resilience of skin |
| CN107997187A (en) * | 2018-02-05 | 2018-05-08 | 上海极迦生物科技有限公司 | With improvement skin elasticity and delay wrinkle systematic function composition and its application |
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