CN107982483A

CN107982483A - A kind of Chinese medicine composition that can effectively treat gout

Info

Publication number: CN107982483A
Application number: CN201711132259.1A
Authority: CN
Inventors: 孙思远
Original assignee: Sichuan Yichuang Biotechnology Co Ltd
Current assignee: Sichuan Yichuang Biotechnology Co Ltd
Priority date: 2017-11-15
Filing date: 2017-11-15
Publication date: 2018-05-04

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of Chinese medicine composition that can effectively treat gout according to the understanding mechanism of Chinese traditional treatment gout, each component and its mass parts ratio of the Chinese medicine composition are as follows：60~150g of caulis piperis futokadsurae, 30~150g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 100~360g of black soya bean, 150~300g of radix rehmanniae recen, 30~150g of radix glycyrrhizae, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 60~120g of rhizoma alismatis, 40~120g of the radix paeoniae rubrathe, 60~160g of the stem of noble dendrobium, 30~70g of myrrh, 90~160g of ramulus mori；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of Chinese medicine composition that can effectively treat gout

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition that can effectively treat gout, particularly The field of the Chinese medicine composition used for patient with gout.

Background technology

Shown according to related document：Gout is by monosodium urate salt（MSU）Crystal correlation arthropathy caused by deposition, it is and fast Purine metabolic disorder and（Or）Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and slow Property tophus disease, mainly include acute attack arthritis, tophus formation, tophaceous chornic arthritis, lithate kidney Sick and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout often with Central obesity, hyperlipidemia, Hypertension, diabetes B and cardiovascular disease etc. show.

So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, the purpose of the invention is to provide a kind of Chinese medicine composition that can effectively treat gout, to solve patient with gout early The problem of getting well.The medicine be using common Chinese medicine as raw material, can be effective by selecting rational medicine and mass parts ratio Treat above-mentioned gout.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：Gout can effectively be treated by providing one kind Chinese medicine composition, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows：

It is 60~150g of caulis piperis futokadsurae, 30~150g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 100~360g of black soya bean, 150~300g of radix rehmanniae recen, sweet 30~150g of grass, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 60~120g of rhizoma alismatis, 40~120g of the radix paeoniae rubrathe, 60~160g of the stem of noble dendrobium, 30~70g of myrrh, 90~160g of ramulus mori, auxiliary material：Talcum powder and appropriate starch.

A kind of Chinese medicine composition that can effectively treat gout, it is characterised in that each component of the Chinese medicine composition and Mass parts are than as follows：

It is 70~130g of caulis piperis futokadsurae, 38~130g of Cortex Phellodendri, 38~105g of Cortex Magnoliae Officinalis, 115~320g of black soya bean, 180~260g of radix rehmanniae recen, sweet 38~130g of grass, 38~105g of curcuma zedoary, 180~400g of tortoiseshell, 70~105g of rhizoma alismatis, 48~105g of the radix paeoniae rubrathe, 70~140g of the stem of noble dendrobium, 38~60g of myrrh, 100~140g of ramulus mori, auxiliary material：Talcum powder and appropriate starch.

Caulis piperis futokadsurae 115g, Cortex Phellodendri 115g, Cortex Magnoliae Officinalis 95g, black soya bean 260g, radix rehmanniae recen 230g, radix glycyrrhizae 118g, curcuma zedoary 95g, tortoiseshell 350g, rhizoma alismatis 95g, radix paeoniae rubrathe 95g, stem of noble dendrobium 120g, myrrh 52g, ramulus mori 120g, auxiliary material：Talcum powder and appropriate starch.

A kind of Chinese medicine composition that can effectively treat gout, it is characterised in that described method includes following steps prepare and Into：

A, after above-mentioned raw materials Chinese medicine being picked impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into after soaking 40min in cold boiling water, then soaked medicine is put into marmite and is decocted Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow boiling and boils 115 Min, leaching liquid；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned Slow boiling boils 105 min, leaching liquid；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct During to 8min, turn slow boiling and boil 90 min, leaching liquid；4. merging liquid three times, and it is concentrated under reduced pressure into every milliliter contained 3g Standard after, that is, obtain drug extract.

C, by the extract dry prepared in above-mentioned B, disinfection, and it is spare according to mass parts ratio to be ground into superfine end；

D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh thing mistake ground in C After sieve, then above-mentioned starch and talcum powder are put into medicine device in the lump and are uniformly mixed, be then prepared into capsule（After its capsule is sealed Total length be 23.3mm, medicinal powder capacity 0.4~0.5g/）, then polish, sterilize, sealed packaging to obtain the final product.

A kind of Chinese medicine composition that can effectively treat gout, it is characterised in that the instructions of taking is：The glue that will be prepared Wafer medicine is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, warm water delivery service.15 days are one The course for the treatment of, after treating 3~6 courses for the treatment of, symptom is wholly absent, and is checked：Blood uric acid recovers normal.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Caulis piperis futokadsurae, nature and flavor：Acrid flavour, hardship, slightly warm in nature, have the effect of wind-damp dispelling, degrading the channel, stopping numbness pain, wet for treating chill The diseases such as numbness, podomere pain, muscle arteries and veins contraction, joint stuffiness；

Cortex Phellodendri, nature and flavor：It is bitter, cold, there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, for treat damp-heat dysentery, Jaundice, band under, heat gonorrhea, tinea pedis, impotence ward off, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema itch, stir-baked CORTEX PHELLODENDRI with salt solution enriching yin drop Fire, for fire excess from yin deficiency, night sweat hectic fever due to yin；

Cortex Magnoliae Officinalis, nature and flavor：It is bitter, pungent, warm, there is eliminating dampness dissolving phlegm, lower gas removes full, for damp retention in middle-jiao, abdominal fullness and distention, food Pneumatosis is stagnant, abdominal distention constipation, sputum cough；In addition, seven feelings pent-ups, mental disorder mutual resistance, hinders in pharynx if any thing, pharynx not under, spit no The globus hysteriocus card gone out, also can use this product eliminating dampness dissolving phlegm, the effect during lower gas is wide；

Black soya bean, nature and flavor：It is sweet, flat, there is the effect of benefiting shrewd head, nourishing the blood to expel wind, Li Shui, removing toxic substances, for treating deficiency of Yin polydipsia, head Dizzy blurred vision, body void hidrosis, lumbago due to the kidney deficiency, oedema oliguria, numbness pain contraction, numb in every limb, medicine food poisoning；

Radix rehmanniae recen, nature and flavor：It is sweetness and bitterness, cool, there is the effect of clearing heat and promoting fluid enriching yin, blood-nourishing, for treating fever due to yin deficiency, quenching one's thirst, spit Blood, bleeding from five sense organs or subcutaneous tissue, metrorrhagia, irregular menstruation, fetal irritability, impairment of yin constipation；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swell in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；

Curcuma zedoary, nature and flavor：Toil, temperature, have the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation, Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has Effect：Its aromatic turmeric oil preparation is in vitro to the L615 leukaemia and ascitic type of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred lines The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb Art plays the role of directly killing oncocyte；

Tortoiseshell, nature and flavor：It is salty sweet, flat, there is the effect of enriching yin, checking exuberance of yang, kidney tonifying, strong bone, for treating the deficiency of the kidney yin, hectic fever due to yin labor Heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, band under, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, children's fontanel Do not conform to；

Rhizoma alismatis, nature and flavor：It is sweet in flavor, light, cold in nature, have clearing damp and promoting diuresis, expel the heat-evil, change the effect of turbid lipid-loweringing, for treat difficult urination, Oedema turgor, oliguria of having loose bowels, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia lump in the abdomen accumulation, injury from falling down；

The stem of noble dendrobium, nature and flavor：It is sweet, be slightly cold, there is the effect of beneficial stomach that promotes the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, improving eyesight strong waist, for treating Consumption of body fluid caused by febrile disease, dry polydipsia, deficiency of stomach-Yin, stomachache retch, dryness of the lung dry cough, abnormal heat are not moved back, impairment of yin mesh is dark, waist and knee is weak；

Myrrh, nature and flavor：It is acrid flavour, hardship, mild-natured, there is the effect of scattered stasis pain, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty The illnesss such as pain, dysmenorrhoea Amenorrhea, postpartum stasis, Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, carbuncle swells sore；

Ramulus mori, nature and flavor：It is mildly bitter flavor, mild-natured, there is the effect of wind-damp dispelling, sharp joint, for treating Bi condition, shoulder arm, joint The diseases such as numbness of aching.

Medicine of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For：With regard to gout, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gout, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of Chinese medicine composition that can effectively treat gout, it is characterised in that each component and quality of the Chinese medicine composition Part is than as follows：

Embodiment 2：

Caulis piperis futokadsurae 130g, Cortex Phellodendri 130g, Cortex Magnoliae Officinalis 105g, black soya bean 320g, radix rehmanniae recen 260g, radix glycyrrhizae 130g, curcuma zedoary 105g, tortoiseshell 400g, rhizoma alismatis 105g, radix paeoniae rubrathe 105g, stem of noble dendrobium 140g, myrrh 60g, ramulus mori 140g, auxiliary material：Talcum powder and appropriate starch.

Embodiment 3：

Caulis piperis futokadsurae 150g, Cortex Phellodendri 150g, Cortex Magnoliae Officinalis 120g, black soya bean 360g, radix rehmanniae recen 300g, radix glycyrrhizae 150g, curcuma zedoary 120g, tortoiseshell 450g, rhizoma alismatis 120g, radix paeoniae rubrathe 120g, stem of noble dendrobium 160g, myrrh 70g, ramulus mori 160g, auxiliary material：Talcum powder and appropriate starch.

Model case：

Through clinical conditions patient with gout totally 1386, the age is 817 of more than 53 years old, and only 569 are less than 53 years old. Blood uric acid recovers normally have 925, effective 322, invalid 139 in 1386 patients.Total effective rate is up to 90%.

Claims

A kind of 1. Chinese medicine composition that can effectively treat gout, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：

It is 60~150g of caulis piperis futokadsurae, 30~150g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 100~360g of black soya bean, 150~300g of radix rehmanniae recen, sweet 30~150g of grass, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 60~120g of rhizoma alismatis, 40~120g of the radix paeoniae rubrathe, 60~160g of the stem of noble dendrobium, 30~70g of myrrh, 90~160g of ramulus mori, auxiliary material：Talcum powder and appropriate starch.
2. the Chinese medicine composition according to claim 1 that can effectively treat gout, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：

It is 70~130g of caulis piperis futokadsurae, 38~130g of Cortex Phellodendri, 38~105g of Cortex Magnoliae Officinalis, 115~320g of black soya bean, 180~260g of radix rehmanniae recen, sweet 38~130g of grass, 38~105g of curcuma zedoary, 180~400g of tortoiseshell, 70~105g of rhizoma alismatis, 48~105g of the radix paeoniae rubrathe, 70~140g of the stem of noble dendrobium, 38~60g of myrrh, 100~140g of ramulus mori, auxiliary material：Talcum powder and appropriate starch.
3. the Chinese medicine composition that can effectively treat gout according to claim 1 to 2, it is characterised in that the Chinese medicine group The each component and its mass parts of compound are than as follows：

Caulis piperis futokadsurae 115g, Cortex Phellodendri 115g, Cortex Magnoliae Officinalis 95g, black soya bean 260g, radix rehmanniae recen 230g, radix glycyrrhizae 118g, curcuma zedoary 95g, tortoiseshell 350g, rhizoma alismatis 95g, radix paeoniae rubrathe 95g, stem of noble dendrobium 120g, myrrh 52g, ramulus mori 120g, auxiliary material：Talcum powder and appropriate starch.