CN107982482A - A kind of new medicine composition for treating gout and preparation method - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of new medicine composition for treating gout according to the understanding mechanism of Chinese traditional treatment gout, each component and its mass parts ratio of the Chinese medicine composition are as follows：150~550g of adlay, 60~160g of Lygodium japonicum, 30~160g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 90~160g of Poria cocos, 60~120g of the root of Chinese clematis, 30~130g of radix glycyrrhizae, 90~160g of the Chinese bulbul, 30~120g of curcuma zedoary, 50~120g of stiff silkworm, 60~120g of rhizoma alismatis, 30~120g of the membrane of a chicken's gizzard, 30~120g of bulbus fritillariae cirrhosae, 60~160g of the stem of noble dendrobium, 150~280g of reticulate millettia；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of new medicine composition for treating gout and preparation method

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of new medicine composition for treating gout, particularly supplies The new medicine composition and the field of preparation method that patient with gout uses.

Background technology

Shown according to related documents and materials：Gout is by monosodium urate salt（MSU）Crystal correlation arthropathy caused by deposition, With purine metabolic disturbance and（Or）Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis With chronic gout stone disease, mainly include acute attack arthritis, tophus formation, tophaceous chornic arthritis, uric acid Salt nephrosis and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout is often with Central obesity, hyperlipemia Disease, hypertension, diabetes B and cardiovascular disease etc. show.

So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, it is extensive early to solve patient with gout the purpose of the invention is to provide a kind of new medicine composition for treating gout The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be controlled Treat above-mentioned gout.

To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is：There is provided and a kind of treat the new of gout Chinese medicine composition and preparation method, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows：

150~550g of adlay, 60~160g of Lygodium japonicum, 30~160g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 90~160g of Poria cocos, Wheeling 60~120g of celestial being, 30~130g of radix glycyrrhizae, 90~160g of the Chinese bulbul, 30~120g of curcuma zedoary, 50~120g of stiff silkworm, rhizoma alismatis 60~ 120g, 30~120g of the membrane of a chicken's gizzard, 30~120g of bulbus fritillariae cirrhosae, 60~160g of the stem of noble dendrobium, 150~280g of reticulate millettia, auxiliary material：Starch is fitted Amount.

A kind of new medicine composition for treating gout and preparation method, it is characterised in that the Chinese medicine composition it is each A component and mass parts are than as follows：

180~480g of adlay, 70~140g of Lygodium japonicum, 38~140g of Cortex Phellodendri, 38~105g of Cortex Magnoliae Officinalis, 100~140g of Poria cocos, Wheeling 70~105g of celestial being, 38~118g of radix glycyrrhizae, 100~140g of the Chinese bulbul, 38~105g of curcuma zedoary, 58~105g of stiff silkworm, rhizoma alismatis 70~ 105g, 38~105g of the membrane of a chicken's gizzard, 38~105g of bulbus fritillariae cirrhosae, 70~140g of the stem of noble dendrobium, 180~250g of reticulate millettia, auxiliary material：Starch is fitted Amount.

A kind of new medicine composition for treating gout and preparation method, it is characterised in that the Chinese medicine composition it is each A component and mass parts are than as follows：

Adlay 420g, Lygodium japonicum 120g, Cortex Phellodendri 120g, Cortex Magnoliae Officinalis 95g, Poria cocos 120g, root of Chinese clematis 95g, radix glycyrrhizae 100g, the Chinese bulbul 120g, curcuma zedoary 95g, stiff silkworm 95g, rhizoma alismatis 95g, the membrane of a chicken's gizzard 95g, bulbus fritillariae cirrhosae 95g, stem of noble dendrobium 120g, reticulate millettia 220g, auxiliary material：Form sediment Appropriate powder.

A kind of new medicine composition for treating gout and preparation method, it is characterised in that the described method includes following step Suddenly it is prepared：

A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and drying, it is ground into superfine end according to mass parts ratio and treats With；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch are sieved, is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, sealed packaging is Can.

It is a kind of to be used to treat the Chinese medicine composition and preparation method of gout, it is characterised in that the instructions of taking is：Will system The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, and dosage 6g/time, warm water delivery service.It is within 15 days One course for the treatment of, treats 4~7 courses for the treatment of, checks：Blood uric acid recovers normal.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component：

Adlay, nature and flavor：It is sweet, light, be slightly cold, have dampness removing invigorating the spleen, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus the effect of, for treating oedema, foot Under gas, dribbling urination, damp-warm diseases, diarrhea band, the disease such as arthralgia pain due to rheumatism, muscle arteries and veins contraction, lung carbuncle, acute appendicitis, flat wart；

Lygodium japonicum, nature and flavor：It is sweet in flavor, salty, cold in nature, there is the effect of eliminating dampness and heat, treating stranguria analgesic, for treating heat gonorrhea, urolithiasis, blood Leaching, cream leaching, Urethra astringent pain；

Cortex Phellodendri, nature and flavor：It is bitter, cold in nature, have effects that there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, for treating Damp-heat dysentery, jaundice, with lower pruritus vulvae, puckery pain of heat gonorrhea, tinea pedis impotence knit, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema Wet sore, stir-baked CORTEX PHELLODENDRI with salt solution nourishing yin and lessening fire, for fire excess from yin deficiency, night sweat hectic fever due to yin；

Cortex Magnoliae Officinalis, nature and flavor：It is bitter, pungent, warm, have eliminating dampness dissolving phlegm, lower gas removes full the effect of, for treat damp retention in middle-jiao, abdominal fullness and distention, Stagnation of QI due to dyspepsia, abdominal distention constipation, sputum cough；In addition, seven feelings pent-ups, mental disorder mutual resistance, hinders in pharynx if any thing, pharynx not under, spit it The globus hysteriocus card not gone out, also can use this product eliminating dampness dissolving phlegm, the effect during lower gas is wide；

Poria cocos, nature and flavor：It is mild-natured, sweet in flavor, light, there is the effect of clearing damp and promoting diuresis, invigorating the spleen calming heart, belong to damp-clearing drug subordinate classification Edema-alleviating diuretic, for treating oedema oliguria, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear；

The root of Chinese clematis, nature and flavor：It is acrid flavour, salty, warm-natured, there is the effect of wind-damp dispelling, degrading the channel, for treating arthralgia pain due to rheumatism, limbs fiber crops Wood, muscle arteries and veins contraction, joint stuffiness；

Radix glycyrrhizae, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swell in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；

The Chinese bulbul, nature and flavor：It is bitter, cold, there is the effect of clearing heat and detoxicating, to remove heat from the blood and relieve diarrhea, for treating under toxic-heat and blood stasis, pruritus vulvae band；

Curcuma zedoary, nature and flavor：Toil, temperature, have the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation, Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has Effect：Its aromatic turmeric oil preparation is in vitro to the L615 leukaemia and ascitic type of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred lines The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb Art plays the role of directly killing oncocyte；

Stiff silkworm, nature and flavor：Taste is salty, pungent, mild-natured, has the effect of Inflammation Zhijing, wind-expelling pain-stopping, reducing phlegm and resolving masses, for treating liver wind Press from both sides phlegm, twitch, acute infantile convulsion, lockjaw, middle air port, headache due to pathogenic wind-heat, hot eyes pharyngalgia, rubella itch, hair chin or cheek mumps；

Rhizoma alismatis, nature and flavor：It is sweet in flavor, light, cold in nature, have clearing damp and promoting diuresis, expel the heat-evil, change the effect of turbid lipid-loweringing, for treat difficult urination, Oedema turgor, oliguria of having loose bowels, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia；

The membrane of a chicken's gizzard, nature and flavor：It is sweet, flat, have stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil the effect of, for treat dyspepsia, Vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of urolithiasis, courage is swollen hypochondriac pain；

Bulbus fritillariae cirrhosae, nature and flavor：Cool in nature, Gan Ping, has the effect of resolving sputum and relieving asthma that moistens the lung and relieve the cough, clearing heat and eliminating phlegm, dry for treating lung heat Cough, dry cough lack the diseases such as phlegm, deficiency of yin and overstrain cough, blood-stained sputum, scrofula, acute mastitis, lung carbuncle；

The stem of noble dendrobium, nature and flavor：It is sweet, be slightly cold, there is the effect of beneficial stomach that promotes the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, improving eyesight strong waist, for treating Consumption of body fluid caused by febrile disease, dry polydipsia, deficiency of stomach-Yin, stomachache retch, dryness of the lung dry cough, abnormal heat are not moved back, impairment of yin mesh is dark, waist and knee is weak；

Reticulate millettia, nature and flavor：It is bitter, micro-sweet, warm-natured, there is the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation, for treat it is numb in every limb, Quadriplegia, arthralgia pain due to rheumatism, women have through diseases such as uncomfortable, dysmenorrhoea, amenorrhoeas.

Medicine of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For：With regard to gout, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gout, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of new medicine composition for treating gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Adlay 420g, Lygodium japonicum 120g, Cortex Phellodendri 120g, Cortex Magnoliae Officinalis 95g, Poria cocos 120g, root of Chinese clematis 95g, radix glycyrrhizae 100g, the Chinese bulbul 120g, curcuma zedoary 95g, stiff silkworm 95g, rhizoma alismatis 95g, the membrane of a chicken's gizzard 95g, bulbus fritillariae cirrhosae 95g, stem of noble dendrobium 120g, reticulate millettia 220g, auxiliary material：Form sediment Appropriate powder.

Embodiment 2：

A kind of new medicine composition for treating gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Adlay 480g, Lygodium japonicum 140g, Cortex Phellodendri 140g, Cortex Magnoliae Officinalis 105g, Poria cocos 140g, root of Chinese clematis 105g, radix glycyrrhizae 118g, the Chinese bulbul 140g, curcuma zedoary 105g, stiff silkworm 105g, rhizoma alismatis 105g, the membrane of a chicken's gizzard 105g, bulbus fritillariae cirrhosae 105g, stem of noble dendrobium 140g, reticulate millettia 250g, it is auxiliary Material：Appropriate starch.

Embodiment 3：

A kind of new medicine composition for treating gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows：

Adlay 550g, Lygodium japonicum 160g, Cortex Phellodendri 160g, Cortex Magnoliae Officinalis 120g, Poria cocos 160g, root of Chinese clematis 120g, radix glycyrrhizae 130g, the Chinese bulbul 160g, curcuma zedoary 120g, stiff silkworm 120g, rhizoma alismatis 120g, the membrane of a chicken's gizzard 120g, bulbus fritillariae cirrhosae 120g, stem of noble dendrobium 160g, reticulate millettia 280g, it is auxiliary Material：Appropriate starch.

Model case：

Through clinical conditions patient with gout totally 1355, the age is 810 of more than 58 years old, and only 545 are less than 58 years old. Blood uric acid recovers normally have 910, effective 323, invalid 122 in 1355 patients.Total effective rate is up to 91%.

Claims (3)

1. a kind of new medicine composition for treating gout, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows：

150~550g of adlay, 60~160g of Lygodium japonicum, 30~160g of Cortex Phellodendri, 30~120g of Cortex Magnoliae Officinalis, 90~160g of Poria cocos, Wheeling 60~120g of celestial being, 30~130g of radix glycyrrhizae, 90~160g of the Chinese bulbul, 30~120g of curcuma zedoary, 50~120g of stiff silkworm, rhizoma alismatis 60~ 120g, 30~120g of the membrane of a chicken's gizzard, 30~120g of bulbus fritillariae cirrhosae, 60~160g of the stem of noble dendrobium, 150~280g of reticulate millettia, auxiliary material：Starch is fitted Amount.

2. the new medicine composition for the treatment of gout according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows：

180~480g of adlay, 70~140g of Lygodium japonicum, 38~140g of Cortex Phellodendri, 38~105g of Cortex Magnoliae Officinalis, 100~140g of Poria cocos, Wheeling 70~105g of celestial being, 38~118g of radix glycyrrhizae, 100~140g of the Chinese bulbul, 38~105g of curcuma zedoary, 58~105g of stiff silkworm, rhizoma alismatis 70~ 105g, 38~105g of the membrane of a chicken's gizzard, 38~105g of bulbus fritillariae cirrhosae, 70~140g of the stem of noble dendrobium, 180~250g of reticulate millettia, auxiliary material：Starch is fitted Amount.

3. the new medicine composition of the treatment gout according to claim 1 to 2, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows：

Adlay 420g, Lygodium japonicum 120g, Cortex Phellodendri 120g, Cortex Magnoliae Officinalis 95g, Poria cocos 120g, root of Chinese clematis 95g, radix glycyrrhizae 100g, the Chinese bulbul 120g, curcuma zedoary 95g, stiff silkworm 95g, rhizoma alismatis 95g, the membrane of a chicken's gizzard 95g, bulbus fritillariae cirrhosae 95g, stem of noble dendrobium 120g, reticulate millettia 220g, auxiliary material：Form sediment Appropriate powder.