CN104771588A - Traditional Chinese medicine composition for treating nephrotic syndrome caused by deficiency of liver-yin and kidney-yin - Google Patents

Traditional Chinese medicine composition for treating nephrotic syndrome caused by deficiency of liver-yin and kidney-yin Download PDF

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CN104771588A
CN104771588A CN201510200069.3A CN201510200069A CN104771588A CN 104771588 A CN104771588 A CN 104771588A CN 201510200069 A CN201510200069 A CN 201510200069A CN 104771588 A CN104771588 A CN 104771588A
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parts
yin
kidney
liver
nephrotic syndrome
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黄萍
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黄萍
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Abstract

The invention discloses a traditional Chinese medicine composition for treating nephrotic syndrome caused by deficiency of liver-yin and kidney-yin. The composition is characterized by being prepared from the following medicinal materials in parts by weight: 15-20 parts of herminium monorchis, 10-15 parts of geum urbanum, 12-15 parts of asiatic alectoria filament, 3-6 parts of morina chinensis, 20-25 parts of cuneate lespedeza herb with root, 5-10 parts of diversifolious osmanthus branchlet leaf and bark, 6-9 parts of cortex acanthopanacis, 10-15 parts of astragalus complanatus, 10-15 parts of dendrobium densiflorum lindl ex wall, 5-10 parts of sericeous cinquefoil root, 12-15 parts of sisymbr iumislandicum oed, 20-25 parts of rosa multiflora thunb, 12-15 parts of fructus catalpae, 10-15 parts of thinleaf buckthorn fruit and 6-9 parts of semen pharbitidis. The traditional Chinese medicine composition has the advantages of high effective rate, reliable curative effect and relapse prevention after healing when used for treating nephrotic syndrome caused by deficiency of liver-yin and kidney-yin.

Description

A kind of Chinese medicine composition for the treatment of liver-kidney yin deficiency nephrotic syndrome
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine composition being used for the treatment of liver-kidney yin deficiency nephrotic syndrome.
Background technology
Nephrotic syndrome is generally main clinical manifestation with edema, belongs to " edema " category of the traditional Chinese medical science.Nephrotic syndrome acts on body by many reasons, causes lung, spleen, the dirty functional disorder of kidney three.Insufficiency of the spleen then failure of the spleen to transport and transform, is difficult to absorb precise and tiny and defeated water distribution liquid; Suffer from a deficiency of the kidney, open entire not normal, can not astringency inducing vital essence and excretion turbid damp.Spleen is ascending the clear and descending the turbid not, gradually causes edema, albuminuria, hypoproteinemia and hyperlipemia.Its reason mainly contain following some: 1., exopathogen invasion and attack.Return in the wet dipping of exposure to the wind after sweating due to overstrain or water or virus, cause internal organs to be become estranged, qi and blood disorder, dysfunction of the spleen in transportation, kidney loses that envelope is hidden, the normal function of main water, and with the passing of time water wets in all heresies and contains, and healthy energy is more empty, can form primary disease.2., retention of damp-heat in the interior.Pathogenic factor is stayed for a long time, strongly fragrant and heat-transformation, then consumes the moon of impairing the liver kidney.Liver controlling conveyance and dispersion and store blood, depression of liver-QI also can cause blood stasis causing water retention.3., deficiency-weakness of spleen-QI.Temper element void or drinking and eating irregularly impairing the spleen and stomach, cause precise and tiny not life, and water is wet not to be transported, and damp stops gathering, and sends out as primary disease.4., deficiency of kidney-QI.Ferritic deficiency of kidney-QI or sexual overstrain, or delivery and feed infant is too much, kidney qi is impaired, kidney lose open entire, can not promote the circulation of qi and water, retention of water-damp in the body, forms edema.Spleen loses helping of kidney yang, does not transport, and the logical tune of lung is had no right, then water does not fall, thus heavy water swells more.At present, the symptomatic drug treatment such as inducing diuresis to remove edema, glucocorticoid, immunosuppressant that doctor trained in Western medicine is used, can only the respite state of an illness, and side effect is obvious, and is very easy to repeatedly.And Chinese traditional treatment requires the feature of " global theory ", be not that pathological changes is confined on kidney, particularly Patients With Nephrotic Symdrome often multiple organs and systems get involved, the state of an illness is complicated, influences each other, in this case, the traditional Chinese medical science uses the theory of yin-yang and five elements (metal, wood, water, fire and earth), overall conditioning, strengthening vital QI to eliminate pathogenic factors, not only can alleviate the complication of nephropathy, the side effect of Western medicine can also be stopped.The nephrotic syndrome that the traditional Chinese medical science causes according to different reason, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: yang deficiency of spleen and stomache, liver-kidney yin deficiency, type of deficiency of both QI and YIN, wind-heat invading lung type, stagnation of QI water retention type, stagnation of damp-heat type.At present, the Chinese medicine for the treatment of nephrotic syndrome is a lot, but uncommon for the Chinese medicine composition of liver-kidney yin deficiency nephrotic syndrome, and to there is after drug withdrawal the easily defect such as repeatedly.
Summary of the invention
Object of the present invention aims to provide a kind of Chinese medicine composition for the treatment of liver-kidney yin deficiency nephrotic syndrome, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing liver-kidney yin deficiency nephrotic syndrome.
For achieving the above object, the present invention by the following technical solutions: a kind of Chinese medicine composition for the treatment of liver-kidney yin deficiency nephrotic syndrome, is characterized in that being made up of the medical material of following weight proportion:
Careless 12-15 part, Fructus rosae multiflorae 20-25 part, Fructus catalpae ovatae 12-15 part, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10-15 part, Semen Pharbitidis 6-9 part before musk orchid 15-20 part, the fragrant 10-15 part of bodhi, Alectoria asiatica Du Rietz 12-15 part, Herba Morinae chinensis 3-6 part, Herba Lespedezae Cuneatae 20-25 part, Cortex Osmanthi Heterophylli 5-10 part, Cortex Acanthopancis 6-9 part, Semen Astragali Complanati 10-15 part, Dendrobium densiflorum lindl. 10-15 part, Radix Potentillae sericophyllae 5-10 part, water.
Source and the function of medical material involved in formula cure mainly as follows:
Musk orchid [source] the orchid family Herminium plant musk orchid Herminium monorchis (L.) R. Brown., is used as medicine with whole herb with root.Autumn excavates, and dries.[nature and flavor] are sweet, temperature.[function cures mainly] enriching yin and nourishing kidney, nourishing the stomach, regulating menstruation.For neurasthenia, dizzy insomnia, irritated thirsty, inappetence, early whitening of beard and hair, menoxenia.
Bodhi perfume (or spice) [source] Rosaceae bodhi fragrant Geum urbanum L., with all herbal medicine.[nature and flavor] are pungent, sweet, flat.[function cures mainly] enriching yin and nourishing kidney, suppressing the hyperactive liver improving eyesight, reducing swelling and alleviating pain.Cure cold, dizziness headache, hypertension, anemia, chronic enterogastritis, menoxenia, mastitis, the diseases such as sore.
Alectoria asiatica Du Rietz [source] medical material Ji Yuan: for Usneaceae plant Asia tree send out, double-colored tree sends out, set send out, thallus that ditch tree sends out.[nature and flavor] are light; Property flat [return through] liver; Kidney; Urinary bladder channel [function cures mainly] nourishing the kidney and liver; Arresting seminal emission hidroschesis; Inducing diuresis to remove edema; Removing dampness sore.Main kidney deficiency and bodily weakness; The vertigo; Cardiopalmus; Seminal emission; Night sweat; Stranguria; Edema; Impetigo.
Herba Morinae chinensis [source] medical material Ji Yuan: be herb or the seed of Dipsacaceae plant Herba Morinae chinensis.[nature and flavor] acrid in the mouth; Sweet; [function cures mainly] warm in nature wind-damp dispelling; Invigorating the liver and kidney; Subduing inflammation.Main air pain of dampness syndrome; Soreness of waist and knee joint; Dizzy; Frequent micturition; Sore, carbuncle and painful swelling.
Herba Lespedezae Cuneatae [source] medical material Ji Yuan: be herb or the root of leguminous plant Herba Lespedezae Cuneatae.[nature and flavor] bitter, puckery, cool [return through] lung; Liver; Kidney channel [function cures mainly] the kidney invigorating arresting seminal emission; Invigorating spleen to remove dampness; Preventing phlegm from forming and stopping coughing; Heat-clearing and toxic substances removing.Master suffers from a deficiency of the kidney; Seminal emission; The enuresis; Frequent micturition; Nebulousurine; Leukorrhagia; Have loose bowels; Dysentery; Edema; Infantile malnutrition; Cough and asthma; Traumatic injury; Conjunctival congestion and swelling pain; Carbuncle pyogenic infections from tumour or sore; Insect-bite.
Cortex Osmanthi Heterophylli [source] medical material Ji Yuan: the bark set for Oleaceae plants Hiiragi and branch and leaf.[nature and flavor] micro-hardship; [function cures mainly] cool in nature invigorating the liver and kidney; Strong waist knee joint; Disappear sore.Main weakness of the waist and knees; Carbuncle furunculosis; Pertussis.
Cortex Acanthopancis [source] medical material Ji Yuan: be the root bark of Araliaceae acanthopanax gracilistylus and Acanthopanax sessiliflorus(Rupr.et Maxim.) Seem..[nature and flavor] acrid in the mouth; Bitter; Micro-sweet; [return through] warm in nature returns liver; Kidney channel [function cures mainly] wind-damp dispelling; Invigorating the liver and kidney; Bone and muscle strengthening; To invigorate blood circulation arteries and veins.Main anemofrigid-damp arthralgia; Lumbocrural pain; Muscles and bones flaccidity is soft; Children's's walking retardation in children; Body void is frail; Traumatic injury; Fracture; Edema; Foot gas; Uncontrolled urination is itched.
The seed that Semen Astragali Complanati [source] is leguminous plant astragatus complanatus or Seem Astragali.In the time of the year when autumn changes into winter, fruit maturation and connect stem when not yet ftractureing and cut off, lays seed, removes impurity, then dry after drying.[nature and flavor] are sweet, temperature.[return through] enters liver, kidney channel.[function cures mainly] tonifying liver, kidney tonifying, improving eyesight, controlling nocturnal emission with astringent drugs.Treating the liver kidney deficiency, soreness of waist and knee joint, blurred vision, seminal emission premature ejaculation, frequent micturition, the enuresis, hematuria, leucorrhea.
Dendrobium densiflorum lindl. [source] the orchid family Dendrobium densiflorum lindl. Dendrobium densiflorum Lindl ex Wall., with stem be used as medicine [nature and flavor] sweet, light, micro-salty, cold.[function cures mainly] nourishing YIN for benefiting the kidney, promoting the production of body fluid to quench thirst.Aranea calentura, impairment of body fluid, xerostomia excessive thirst, weak after being ill.
Radix Potentillae sericophyllae [source] medical material Ji Yuan: be the tuber of rosaceous plant Potentilla reptans var. sericophylla.[nature and flavor] are sweet; Flat [return through] lung; Spleen; Stomach warp [function cures mainly] YIN nourishing heat extraction, promoting the production of body fluid to quench thirst.Main deficient fever, dyspnea due to deficiency, consumption of body fluid caused by febrile disease, thirsty and dry pharynx, women's foul leukorrhea.
Grass [source] medical material Ji Yuan before water: be the herb of the raw Herba Rorippae in crucifer natural pond.[nature and flavor] are pungent; Bitter; Cool [return through] liver; Urinary bladder channel [function cures mainly] heat-clearing and toxic substances removing; Inducing diuresis to remove edema.Main anemopyretic cold; Laryngopharynx swelling and pain; Jaundice; Gonorrhea; Edema; Arthritis; Carbuncle.
Fructus rosae multiflorae [source] medical material Ji Yuan: be the fruit of Qiang Wei section plant Flos rosae multiflorae.[nature and flavor] acid; Cool; Nontoxic [return through] lung; Spleen; Liver; Urinary bladder channel [function cures mainly] heat-clearing and toxic substances removing, expelling wind and activating blood circulation, inducing diuresis to remove edema.Main sore and toxic, rheumatic arthralgia, articular instability, menoxenia, edema, dysuria.
Fructus catalpae ovatae [source] medical material Ji Yuan: be the fruit of Bignoniaceae plant Chinese catalpa.[nature and flavor] sweet in the mouth; Property flat [return through] kidney; Urinary bladder channel [function cures mainly] inducing diuresis to remove edema.Main dysuria; Edema; Ascites.
Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) [source] medical material Ji Yuan: be the fruit of Rhamnaceae plant fineflower buckthorn.[nature and flavor] are bitter; Puckery; Flat [return through] heart; Spleen; Kidney channel [function cures mainly] relieving dyspepsia; Row water can be just.Main dyspeptic abdominal distention; Edema; Ascites; Constipation.
Semen Pharbitidis [source] medical material Ji Yuan: for dicotyledon scammonia section plant is led a cow or the seed of pharbitis hispida etc.[nature and flavor] toil; Cold [return through] lung; Kidney; Large intestine; The relieving constipation of small intestine meridian [function cures mainly] diuretic; Eliminate the phlegm by drink; Eliminating stagnated food and killing intestinal worms.Main edema; Ascites; Foot gas; Expectorant heap soil or fertilizer over and around the roots is breathed with cough; Constipation; Dyspepsia malnutrition due to parasitic infestation; Lumbago; Scrotal swelling; Swollen ulcer drug; Anal fistula inguinal bubo etc.
The clinical manifestation of liver-kidney yin deficiency nephrotic syndrome is that face and lower limb are all swollen, and companion sees thirst with desire to drink, and bitter taste is indigestion and loss of appetite, constipation with dry stool, feverish sensation in the palms and soles, and body of the tongue is partially red, and thin fur is shown in from, arteries and veins and counts accurately or stringy and thready pulse.Above various raw material is organically combined by the present invention, mutually coordinates between each composition, interacts, made Chinese medicine has the effect such as nourishing the liver and kidney, tonifying YIN diuretic, can treating both the principal and secondary aspects of a disease to liver-kidney yin deficiency nephrotic syndrome, respond well, fundamentally treat this disease.For many years, by the follow-up investigation statistics to 120 these type of patients of example, show that this prescription effective percentage reaches 91.6%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, sampling approach
Be diagnosed as the patient of liver-kidney yin deficiency nephrotic syndrome from my unit over nearly 5 years, the routine patient of random selecting 120, in age 40-70 year, be divided into matched group and treatment group at random, often organize each 60 people.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
2.1 matched group patients use dabuyin pill, and by specification is taken, 8 weeks courses for the treatment of.
The oral the present invention of 2.2 treatment group according to the obtained Chinese medicinal granule of specific embodiment 1, early, middle and late each once.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Complete incidence graph: urine protein is less than 0.3g day, for three days on end.Nephrotic syndrome performance is eliminated completely, and plasma albumin is greater than 35g/L normal renal function.Partial rcsponse: urine protein 0.31g ~ 2.0g/ day, for three days on end, nephrotic syndrome performance is eliminated completely, and renal function takes a turn for the better.Invalid: more than urine protein 2.0g/ day, nephrotic syndrome performance is not eliminated, and renal function is without improvement.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment liver-kidney yin deficiency nephrotic syndrome.
Detailed description of the invention
Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.
Embodiment 1
Take musk orchid 15 grams, fragrant 10 grams of bodhi, Alectoria asiatica Du Rietz 12 grams, Herba Morinae chinensis 3 grams, Herba Lespedezae Cuneatae 20 grams, Cortex Osmanthi Heterophylli 5 grams, Cortex Acanthopancis 6 grams, Semen Astragali Complanati 10 grams, Dendrobium densiflorum lindl. 10 grams, Radix Potentillae sericophyllae 5 grams, the front grass 12 grams of water, Fructus rosae multiflorae 20 grams, Fructus catalpae ovatae 12 grams, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10 grams, Semen Pharbitidis 6 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of liver-kidney yin deficiency nephrotic syndrome.Oral, every bu is taken for early, middle and late three times.
Embodiment 2
Take musk orchid 17 grams, fragrant 13 grams of bodhi, Alectoria asiatica Du Rietz 13 grams, Herba Morinae chinensis 5 grams, Herba Lespedezae Cuneatae 22 grams, Cortex Osmanthi Heterophylli 7 grams, Cortex Acanthopancis 8 grams, Semen Astragali Complanati 12 grams, Dendrobium densiflorum lindl. 12 grams, Radix Potentillae sericophyllae 8 grams, the front grass 13 grams of water, Fructus rosae multiflorae 22 grams, Fructus catalpae ovatae 13 grams, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 14 grams, Semen Pharbitidis 8 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of liver-kidney yin deficiency nephrotic syndrome.Oral, every bu is taken for early, middle and late three times.
Embodiment 3
Take musk orchid 20 grams, fragrant 15 grams of bodhi, Alectoria asiatica Du Rietz 15 grams, Herba Morinae chinensis 6 grams, Herba Lespedezae Cuneatae 25 grams, Cortex Osmanthi Heterophylli 10 grams, Cortex Acanthopancis 9 grams, Semen Astragali Complanati 15 grams, Dendrobium densiflorum lindl. 15 grams, Radix Potentillae sericophyllae 10 grams, the front grass 15 grams of water, Fructus rosae multiflorae 25 grams, Fructus catalpae ovatae 15 grams, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 15 grams, Semen Pharbitidis 9 grams.Above various medical material grinding is become end, then uses conventional method " whole part " to extract and make instant Chinese medicine granule, carry out subpackage according to every pouch 10 grams, airtight, preserve in shady and cool, dry place.
Be used for the treatment of liver-kidney yin deficiency nephrotic syndrome.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat a Chinese medicine composition for liver-kidney yin deficiency nephrotic syndrome, it is characterized in that being made up of the medical material of following weight proportion:
Careless 12-15 part, Fructus rosae multiflorae 20-25 part, Fructus catalpae ovatae 12-15 part, Fructus rhamni leptophyllae (Rhamnus leptophylla Schneid.) 10-15 part, Semen Pharbitidis 6-9 part before musk orchid 15-20 part, the fragrant 10-15 part of bodhi, Alectoria asiatica Du Rietz 12-15 part, Herba Morinae chinensis 3-6 part, Herba Lespedezae Cuneatae 20-25 part, Cortex Osmanthi Heterophylli 5-10 part, Cortex Acanthopancis 6-9 part, Semen Astragali Complanati 10-15 part, Dendrobium densiflorum lindl. 10-15 part, Radix Potentillae sericophyllae 5-10 part, water.
CN201510200069.3A 2015-04-26 2015-04-26 Traditional Chinese medicine composition for treating nephrotic syndrome caused by deficiency of liver-yin and kidney-yin Pending CN104771588A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105709025A (en) * 2016-04-26 2016-06-29 杨招榕 Medicine for treating nephrotic syndrome

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105709025A (en) * 2016-04-26 2016-06-29 杨招榕 Medicine for treating nephrotic syndrome

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Application publication date: 20150715