CN107982499A - A kind of Chinese medicine composition and preparation method for being used to treat gout - Google Patents

A kind of Chinese medicine composition and preparation method for being used to treat gout Download PDF

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CN107982499A
CN107982499A CN201711130091.0A CN201711130091A CN107982499A CN 107982499 A CN107982499 A CN 107982499A CN 201711130091 A CN201711130091 A CN 201711130091A CN 107982499 A CN107982499 A CN 107982499A
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chinese
medicine composition
chinese medicine
magnoliae officinalis
cortex magnoliae
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罗倩茹
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
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    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
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    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/9068Zingiber, e.g. garden ginger

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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of Chinese medicine composition for being used to treat gout be provided according to the understanding mechanism of Chinese traditional treatment gout, each component and its mass parts ratio of the Chinese medicine composition are as follows:150~550g of dandelion, 60~150g of Lygodium japonicum, 150~600g of desmodium, 30~120g of Cortex Magnoliae Officinalis, 30~120g of ginger, 20~70g of Schisandra chinensis, 90~160g of the Chinese bulbul, 30~130g of radix glycyrrhizae, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, 150~450g of tortoiseshell, 100~350g of adlay, 30~120g of the membrane of a chicken's gizzard, 30~80g of fructus amomi, 30~70g of frankincense, 60~160g of the stem of noble dendrobium, 150~300g of reticulate millettia, 40~120g of the radix paeoniae rubrathe;Medicine provided by the invention is a good Chinese prescription.

Description

A kind of Chinese medicine composition and preparation method for being used to treat gout
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition for being used to treat gout, particularly supplies The Chinese medicine composition and the field of preparation method that patient with gout uses.
Background technology
Shown according to related documents and materials:Gout is by monosodium urate salt(MSU)Crystal correlation arthropathy caused by deposition, With purine metabolic disturbance and(Or)Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis With chronic gout stone disease, mainly include acute attack arthritis, tophus formation, tophaceous chornic arthritis, uric acid Salt nephrosis and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout is often with Central obesity, hyperlipemia Disease, hypertension, diabetes B and cardiovascular disease etc. show.
So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will Solve the problems, such as.
The content of the invention
With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, it is extensive early to solve patient with gout the purpose of the invention is to provide a kind of Chinese medicine composition for being used to treat gout The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be controlled Above-mentioned gout one is treated to demonstrate,prove.
To achieve the purpose that foregoing invention, the technical solution adopted in the present invention is:There is provided a kind of for treating gout Chinese medicine composition and preparation method, it is characterised in that each component and mass parts of the Chinese medicine composition are than as follows:
150~550g of dandelion, 60~150g of Lygodium japonicum, 150~600g of desmodium, 30~120g of Cortex Magnoliae Officinalis, 30~120g of ginger, 20~70g of Schisandra chinensis, 90~160g of the Chinese bulbul, 30~130g of radix glycyrrhizae, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, tortoiseshell 150~ 450g, 100~350g of adlay, 30~120g of the membrane of a chicken's gizzard, 30~80g of fructus amomi, 30~70g of frankincense, 60~160g of the stem of noble dendrobium, reticulate millettia 150~300g, 40~120g of the radix paeoniae rubrathe, auxiliary material:Appropriate starch.
It is a kind of to be used to treat the Chinese medicine composition and preparation method of gout, it is characterised in that the Chinese medicine composition it is each A component and mass parts are than as follows:
180~480g of dandelion, 70~130g of Lygodium japonicum, 180~500g of desmodium, 38~105g of Cortex Magnoliae Officinalis, 38~105g of ginger, 26~60g of Schisandra chinensis, 100~140g of the Chinese bulbul, 38~118g of radix glycyrrhizae, 38~105g of cortex magnoliae officinalis, 38~105g of curcuma zedoary, tortoiseshell 180 ~400g, 115~310g of adlay, 38~105g of the membrane of a chicken's gizzard, 38~70g of fructus amomi, 38~60g of frankincense, 70~140g of the stem of noble dendrobium, chicken blood 180~260g of rattan, 46~105g of the radix paeoniae rubrathe, auxiliary material:Appropriate starch.
It is a kind of to be used to treat the Chinese medicine composition and preparation method of gout, it is characterised in that the Chinese medicine composition it is each A component and mass parts are than as follows:
It is dandelion 420g, Lygodium japonicum 118g, desmodium 430g, Cortex Magnoliae Officinalis 95g, ginger 95g, Schisandra chinensis 52g, Chinese bulbul 120g, sweet Careless 105g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, tortoiseshell 350g, adlay 260g, the membrane of a chicken's gizzard 95g, fructus amomi 60g, frankincense 52g, stem of noble dendrobium 120g, Reticulate millettia 230g, radix paeoniae rubrathe 95g, auxiliary material:Appropriate starch.
A kind of Chinese medicine composition and preparation method for being used to treat gout, it is characterised in that the described method includes following step Suddenly it is prepared:
A, in addition to starch, after above-mentioned raw materials Chinese medicine is picked impurity, dust and drying, it is ground into superfine end according to mass parts ratio and treats With;
B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch are sieved, is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent(The granularity of its water-bindered pill is:3.8mm~4.0mm), and then dry, sealed packaging is Can.
It is a kind of to be used to treat the Chinese medicine composition and preparation method of gout, it is characterised in that the instructions of taking is:Will system The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, and dosage 6.5g/time, warm water delivery service.10 days It is as a treatment course, 3~7 courses for the treatment of are treated, are checked:Blood uric acid recovers normal.
Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.It is raw material that the present invention, which selects one of the most common Chinese medicine, gives full play to the pharmacological effect of each component:
Dandelion, nature and flavor:Sweet, slight bitter, tremble with fear, and has the effect of clearing heat and detoxicating, carbuncle that disappears dissipating bind, swollen for treatmentization heat toxin, the evil that disappears Tuberculosis, Detoxicating food-poisoning, dissipate stagnant gas;
Lygodium japonicum, nature and flavor:It is sweet in flavor, salty, cold in nature, there is the effect of eliminating dampness and heat, treating stranguria analgesic, for treating heat gonorrhea, urolithiasis, blood Leaching, cream leaching, Urethra astringent pain;
Desmodium, nature and flavor:Sweet in flavor, salty, cold nature, has removing dampness through diuresis and removing jaundice, inducing diuresis for treating strangurtia, the efficacy of removing toxicity for detumescence effect, for treating Jaundice with damp-heat pathogen, courage the are swollen disease such as hypochondriac pain, urolithiasis, heat gonorrhea, difficulty and pain in micturition, carbuncle swells furunculosis, snakebite and bugbite;
Cortex Magnoliae Officinalis, nature and flavor:It is bitter, pungent, warm, have eliminating dampness dissolving phlegm, lower gas removes full the effect of, for treat damp retention in middle-jiao, abdominal fullness and distention, Stagnation of QI due to dyspepsia, abdominal distention constipation, sputum cough;In addition, seven feelings pent-ups, mental disorder mutual resistance, hinders in pharynx if any thing, pharynx not under, spit it The globus hysteriocus card not gone out, also can use this product eliminating dampness dissolving phlegm, the effect during lower gas is wide;
Ginger, nature and flavor:Acrid flavour, slightly warm in nature, have the effect of relieving exterior syndrome and dispelling cold, warming middle energizer to arrest vomiting, warm lung cough-relieving, removing toxic substances, for treating Anemofrigid cold, taste sympotoms caused by cold factors, gastrofrigid vomiting, lung cold cough, solving toxin of fish and crab;
Schisandra chinensis, nature and flavor:It is sour, sweet, warm, there is the effect of convergence astringent method, nourishing generate fluid, kidney calming, for treating void of coughing long Asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, injury thirst, feeble pulse of losing heart, Heat Diabetes, palpitation and insomnia;
The Chinese bulbul, nature and flavor:It is bitter, cold, there is the effect of clearing heat and detoxicating, to remove heat from the blood and relieve diarrhea, for treating under toxic-heat and blood stasis, pruritus vulvae band;
Radix glycyrrhizae, nature and flavor:It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, use Swell in treatment burnout deficiency of food, the thin face Huang of flesh, palpitation, abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, throat Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning;
Cortex magnoliae officinalis, nature and flavor:It is bitter, pungent, warm-natured, there is the effect of gas consumption product, eliminating dampness except full, relieving asthma, for treating dyspepsia gas Stagnant, abdominal distention constipation, damp retention in middle-jiao, abdominal swelling and diarrhea, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough;
Curcuma zedoary, nature and flavor:Toil, temperature, have the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation, Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has Effect:Its aromatic turmeric oil preparation is in vitro to the L615 leukaemia and ascitic type of Mouse Ehrlich Carcinoma Cells, 615 mouse inbred lines The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb Art plays the role of directly killing oncocyte;
Tortoiseshell, nature and flavor:It is salty sweet, flat, there is the effect of enriching yin, checking exuberance of yang, kidney tonifying, strong bone, for treating the deficiency of the kidney yin, hectic fever due to yin labor Heat, haematemesis, bleeding from five sense organs or subcutaneous tissue, chronic cough, seminal emission, uterine bleeding, band under, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, children's fontanel Do not conform to;
Adlay, nature and flavor:It is sweet, light, be slightly cold, have dampness removing invigorating the spleen, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus the effect of, for treating oedema, foot Under gas, dribbling urination, damp-warm diseases, diarrhea band, the disease such as arthralgia pain due to rheumatism, muscle arteries and veins contraction, lung carbuncle, acute appendicitis, flat wart;
The membrane of a chicken's gizzard, nature and flavor:It is sweet, flat, have stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil the effect of, for treat dyspepsia, Vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of urolithiasis, courage is swollen hypochondriac pain;
Fructus amomi, nature and flavor:It is acrid flavour, warm-natured, there is the effect of dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive, for treat it is wet it is turbid in Resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, pernicious vomiting, fetal irritability;
Frankincense, nature and flavor:Acrid, bitter, warm, has the effect of blood-activating and qi-promoting analgesic, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty Pain, dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore;
The stem of noble dendrobium, nature and flavor:It is sweet, be slightly cold, there is the effect of beneficial stomach that promotes the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, improving eyesight strong waist, for treating Consumption of body fluid caused by febrile disease, dry polydipsia, deficiency of stomach-Yin, stomachache retch, dryness of the lung dry cough, abnormal heat are not moved back, impairment of yin mesh is dark, waist and knee is weak;
Reticulate millettia, nature and flavor:It is bitter, micro-sweet, warm-natured, there is the effect of activating blood and relaxing tendons, nourishing blood for regulating menstruation, for treat it is numb in every limb, Quadriplegia, arthralgia pain due to rheumatism, women have through diseases such as uncomfortable, dysmenorrhoea, amenorrhoeas;
The radix paeoniae rubrathe, nature and flavor:It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, promoting blood circulation, for treat febrile virulent maculae, hematemesis and epistaxis, Discharging fresh blood stool, red eye, swell pain, carbuncle swells sore, amenorrhoea, dysmenorrhoea, collapse band stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, the accumulation of hernia lump in the abdomen, the disease such as injury from falling down.
Medicine of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For:With regard to gout, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.
Embodiment
A kind of Chinese medicine preparation that the present invention is proposed aiming at the treatment of above-mentioned gout, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail:
Embodiment 1:
A kind of Chinese medicine composition for being used to treat gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
It is dandelion 420g, Lygodium japonicum 118g, desmodium 430g, Cortex Magnoliae Officinalis 95g, ginger 95g, Schisandra chinensis 52g, Chinese bulbul 120g, sweet Careless 105g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, tortoiseshell 350g, adlay 260g, the membrane of a chicken's gizzard 95g, fructus amomi 60g, frankincense 52g, stem of noble dendrobium 120g, Reticulate millettia 230g, radix paeoniae rubrathe 95g, auxiliary material:Appropriate starch.
Embodiment 2:
A kind of Chinese medicine composition for being used to treat gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
Dandelion 480g, Lygodium japonicum 130g, desmodium 500g, Cortex Magnoliae Officinalis 105g, ginger 105g, Schisandra chinensis 60g, Chinese bulbul 140g, Radix glycyrrhizae 118g, cortex magnoliae officinalis 105g, curcuma zedoary 105g, tortoiseshell 400g, adlay 310g, the membrane of a chicken's gizzard 105g, fructus amomi 70g, frankincense 60g, the stem of noble dendrobium 140g, reticulate millettia 260g, radix paeoniae rubrathe 105g, auxiliary material:Appropriate starch.
Embodiment 3:
A kind of Chinese medicine composition for being used to treat gout, it is characterised in that each component and mass parts of the Chinese medicine composition Than as follows:
Dandelion 550g, Lygodium japonicum 150g, desmodium 600g, Cortex Magnoliae Officinalis 120g, ginger 120g, Schisandra chinensis 70g, Chinese bulbul 160g, Radix glycyrrhizae 130g, cortex magnoliae officinalis 120g, curcuma zedoary 120g, tortoiseshell 450g, adlay 350g, the membrane of a chicken's gizzard 120g, fructus amomi 80g, frankincense 70g, the stem of noble dendrobium 160g, reticulate millettia 300g, radix paeoniae rubrathe 20g, auxiliary material:Appropriate starch.
Model case:
Through clinical conditions patient with gout totally 1340, the age is 806 of more than 59 years old, and only 534 are less than 59 years old. Blood uric acid recovers normally have 902, effective 317, invalid 121 in 1340 patients.Total effective rate is up to 91%.

Claims (3)

1. a kind of Chinese medicine composition for being used to treat gout, it is characterised in that each component and its matter of the Chinese medicine composition Part is measured than as follows:
150~550g of dandelion, 60~150g of Lygodium japonicum, 150~600g of desmodium, 30~120g of Cortex Magnoliae Officinalis, 30~120g of ginger, 20~70g of Schisandra chinensis, 90~160g of the Chinese bulbul, 30~130g of radix glycyrrhizae, 30~120g of cortex magnoliae officinalis, 30~120g of curcuma zedoary, tortoiseshell 150~ 450g, 100~350g of adlay, 30~120g of the membrane of a chicken's gizzard, 30~80g of fructus amomi, 30~70g of frankincense, 60~160g of the stem of noble dendrobium, reticulate millettia 150~300g, 40~120g of the radix paeoniae rubrathe, auxiliary material:Appropriate starch.
2. the Chinese medicine composition according to claim 1 for being used to treat gout, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows:
180~480g of dandelion, 70~130g of Lygodium japonicum, 180~500g of desmodium, 38~105g of Cortex Magnoliae Officinalis, 38~105g of ginger, 26~60g of Schisandra chinensis, 100~140g of the Chinese bulbul, 38~118g of radix glycyrrhizae, 38~105g of cortex magnoliae officinalis, 38~105g of curcuma zedoary, tortoiseshell 180 ~400g, 115~310g of adlay, 38~105g of the membrane of a chicken's gizzard, 38~70g of fructus amomi, 38~60g of frankincense, 70~140g of the stem of noble dendrobium, chicken blood 180~260g of rattan, 46~105g of the radix paeoniae rubrathe, auxiliary material:Appropriate starch.
3. the Chinese medicine composition for being used to treat gout according to claim 1 to 2, it is characterised in that the Chinese traditional medicine composition The each component and its mass parts of thing are than as follows:
It is dandelion 420g, Lygodium japonicum 118g, desmodium 430g, Cortex Magnoliae Officinalis 95g, ginger 95g, Schisandra chinensis 52g, Chinese bulbul 120g, sweet Careless 105g, cortex magnoliae officinalis 95g, curcuma zedoary 95g, tortoiseshell 350g, adlay 260g, the membrane of a chicken's gizzard 95g, fructus amomi 60g, frankincense 52g, stem of noble dendrobium 120g, Reticulate millettia 230g, radix paeoniae rubrathe 95g, auxiliary material:Appropriate starch.
CN201711130091.0A 2017-11-15 2017-11-15 A kind of Chinese medicine composition and preparation method for being used to treat gout Withdrawn CN107982499A (en)

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