CN106266207A - A kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof - Google Patents
A kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof, this Chinese medicine preparation is made up of following raw material: Radix Gentianae Macrophyllae, Lignum Sappan, Radix Notoginseng, Radix Angelicae Sinensis, Cortex Moutan, Radix Et Rhizoma Rhei, Cortex Periplocae, Radix Rehmanniae, Flos Carthami, Rhizoma Et Radix Notopterygii, Rhizoma Corydalis and Radix Salviae Miltiorrhizae.Concrete preparation method is that each pretreatment of raw material first becomes 20 ~ 60 mesh powder, then according to consumption proportion weighs each taste crude drug, boiling twice, adds crude drug gross mass 8 ~ 10 times amount water for the first time, decocts 1.5～2h, double gauze filters, second time adds crude drug gross mass 4 ~ 6 times amount water, decocts 1～2h, filters, merge twice filtrate, be concentrated into 1/12～1/10 volume of the cumulative volume that adds water.Chinese medicine preparation prepared by the method can be applicable to thromboangiitis obliterans, atherosclerotic obliterans, deep venous thrombosis of lower limbs etc., especially thromboangiitis obliterans, has instant effect, good effect, the advantage such as easy to use.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation treating peripheral vascular disease and
Preparation method.
Background technology
Peripheral angiopathy is " necrosis " or " arthralgia due to stagnation of blood " category in motherland's medical literature.Including thromboangiitis obliterans,
Lower limb vein thrombus, diabetic peripheral neuropathy, Raynaud disease and peripheral polyneuritis etc..
Thromboangiitis obliterans belongs to the category of " necrosis ", and " necrosis " be deficiency of liver-blood mainly due to internal injury is excited,
Excessively, consumption hinders essence and blood and deficiency of the kidney, and insufficiency of primordial QI then the four stages in the course of an epidemic febrile disease runs uncomfortable in strain；Eating and drinking without temperance usually, taste are injured, spleen
Sun is depressed, can not dissipate essence and blood vessels, gradually becomes QI and blood two to lose；It is added with diseases caused by exogenous pathogenic factor to paddle with severe cold, is subject under cold-damp, wound and smoking
Deng stimulating, so that deficiency of the liver and kindey, cold-damp cohesion, stasis blocking meridians, numbness plug is obstructed, and QI-blood circulation the most freely forms.The heresy of cold-damp is easily sent out
For the transient cause of primary disease, immanent cause is deficiency of the liver and kindey, and healthy energy is weak, it is impossible to resist caused by exopathogen, cold-damp be haze it
Heresy, yang-energy of the most easily hurting sb.'s feelings, blood obtains Wen Zehang, and meeting trembles with fear then coagulates, cold blood stasis, meridians blocking barrier, stagnation of QI and blood may bring about pain.Liver blood is not supported then
Numb.Deficiency of kidney-QI then lower limb are soft unable.Toe (finger) is four ends of human body, is easily invaded by cold-damp, insufficiency of kidney-YANG, and yang-energy can not
Fluent four ends then extremity are the warmest.When the strongly fragrant long heat-transformation of cold-damp, hyperactivity of heat bringing about rottenness of muscle then forms ulcer, gangrene.Liver governing tendons, kidney governing bones, therefore this
Phase likely damages the feature of muscles and bones, toe or dactylolysis after being ill.If because of excessive noxious heat, pain is insomnia all night, so that cloudy liquid consumption wound,
The card of impairment of YIN often occurs.The later stage of disease, though toe (finger) bone comes off, pain relief, owing to pus is dripping incessantly, do not close up, with
Cause deficiency of both QI and blood, therefore may occur in which again the symptom of QI and blood deficiency.
Deep venous thrombosis of lower limbs also belongs to the disease of " necrosis ", is owing to blood stasis is stagnated, and blocks venation, and nutrient blood backflow is subject to
Resistance, water Tianjin is excessive, poly-and be wet, occurs that the symptoms such as suffering limb swelling pain, stasis blocking are that pathological change is basic.Primary disease be one not
The process of disconnected change, occurs the damp and hot symptom accumulateing resistance in early days, but along with treatment and the development of the state of an illness, also can be converted into blood stasis dampness
Or cold-damp blood stasis type, the latter because of the long heat-transformation of the stasis of blood, or can be converted into the pattern of syndrome such as deficiency of the liver and kindey or deficiency of spleen-YANG and kidneyYANG again.Face seen in card,
Or with heat as elder generation, or to tremble with fear, or attach most importance to wet, or with void for very, but all the time along with the pathogenesis of " stasis of blood ".
Diabetic peripheral neuropathy, for complication common in diabetes, because scarcity of suffering from a deficiency of the kidney causes imbalance of YIN and YANG, kidney
Deficiency of YIN person then asthenic fire is grown thickly, both the upper lung spleen that burns, and impairment of body fluid consumption liquid causes Tianjin and do not carries blood；Decocting nutrient blood because of deficiency-heat again, hyperamization liquid is dense
Contracting, popular the most smooth.Insufficiency of kidney-YANG person is then difficult biochemistry, neither cloth body fluid, can not agitate again QI and blood, so that arteries and veins cold coagulation is stagnant, and blood flow
Slow.Visible oligospermia of suffering from a deficiency of the kidney destroys " YIN and YANG in a relative equilibrium " state normally, all may result in thrombosis, blood-stasis internal-depression, and venation is lost
Support." arthralgia due to stagnation of blood " is suffered from a deficiency of the kidney like belonging to.
Raynaud disease, modern medicine thinks that it is a kind of peripheral vascular disease caused by autonomic nervous dysfunction, the traditional Chinese medical science
Dialectical not enough for the four stages in the course of an epidemic febrile disease, sense exopathogen or feelings will are hindered again, yang-energy numbness plug, and blood is not smooth, belong to " arthralgia due to stagnation of blood " category." Jin Guiyao
Slightly. an arthralgia due to stagnation of blood asthenia piece " cloud: " arthralgia due to stagnation of blood, faintness in both YIN and YANG, feeble pulse at GUAN portion, CHI-pulse being slightly tense, exterior symptoms general numbness and hypoesthesia, symptoms similar to the migratory arthralgia.”
Peripheral polyneuritis, controls like belonging to the traditional Chinese medical science " arthralgia due to stagnation of blood " opinion.Its pathogeny is due to ferritic blood deficiency, and yang-energy is not
Foot, feels cold-evil again, so that congealing cold with blood stasis, QI-blood circulation is unfavorable, it is impossible to replenishing vital QI with drugs of warm nature four end.
" necrosis " or the generation of " arthralgia due to stagnation of blood " in a word, due to inside and outside composite factor, causes the imbalance between internal organs, and meridians are sent out
Raw numbness plug, QI-blood circulation is disturbed, and is the ultimate principle of morbidity.
Therefore treatment " necrosis " or " arthralgia due to stagnation of blood " should be grasped flexibly, dialectical combines with differential diagnosis of diseases, takes the circumstances into consideration to increase and decrease medication, can
Medicine card is in step with.
The medicine being used for treating peripheral vascular disease the most clinically has MAILUONING ZHUSHEYE, maitong capsule, blood circulation and channel invigorating
Capsule, Radix Ilicis Pubescentis sheet, venation Shutong capsule, thrombus-resisting capsules etc., Chinese patent report 200410013747.7,
200810146980.0,200910083701.5 etc..Although these medicines have certain curative effect, but remain a need for finding preferably treatment
Medicine.Up to now, the most do not find to report about the medicine for the treatment of peripheral vascular disease of the present invention.The present inventor's warp
After the most repeatedly studying, and by the checking repeatedly of clinical trial, finally have found the treatment peripheral vessels disease of more preferable curative effect
Sick medicine, thus complete the present invention.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof, the method
Preparation Chinese medicine preparation can be applicable to thromboangiitis obliterans, atherosclerotic obliterans, deep venous thrombosis of lower limbs,
Superficial thrombophlebitis, Raynaud disease etc., especially thromboangiitis obliterans, have instant effect, good effect, easy to use etc.
Advantage.
In order to achieve the above object, the present invention adopts the following technical scheme that
The invention provides a kind of Chinese medicine preparation treating peripheral vascular disease, be made up of following raw material: Radix Gentianae Macrophyllae 10 ~
20, Lignum Sappan 5 ~ 15, Radix Notoginseng 2 ~ 8, Radix Angelicae Sinensis 5 ~ 15, Cortex Moutan 3 ~ 12, Radix Et Rhizoma Rhei 20 ~ 35, Cortex Periplocae 5 ~ 10, Radix Rehmanniae 5 ~ 10, red
Spend 5 ~ 15, Rhizoma Et Radix Notopterygii 1 ~ 6, Rhizoma Corydalis 1 ~ 8 and Radix Salviae Miltiorrhizae 1 ~ 5.
According to the Chinese medicine preparation of above-mentioned treatment peripheral vascular disease, it is made up of following raw material: Radix Gentianae Macrophyllae 10 ~ 15,
Lignum Sappan 9 ~ 15, Radix Notoginseng 6 ~ 8, Radix Angelicae Sinensis 5 ~ 11, Cortex Moutan 3 ~ 7, Radix Et Rhizoma Rhei 25 ~ 35, Cortex Periplocae 5 ~ 8, Radix Rehmanniae 7 ~ 10, Flos Carthami 12 ~
15, Rhizoma Et Radix Notopterygii 1 ~ 3, Rhizoma Corydalis 4 ~ 8 and Radix Salviae Miltiorrhizae 1 ~ 3.
According to the Chinese medicine preparation of above-mentioned treatment peripheral vascular disease, it is made up of following raw material: Radix Gentianae Macrophyllae 15 ~ 20,
Lignum Sappan 5 ~ 9, Radix Notoginseng 2 ~ 6, Radix Angelicae Sinensis 11 ~ 15, Cortex Moutan 7 ~ 12, Radix Et Rhizoma Rhei 20 ~ 25, Cortex Periplocae 8 ~ 10, Radix Rehmanniae 7 ~ 10, Flos Carthami 5 ~
12, Rhizoma Et Radix Notopterygii 3 ~ 6, Rhizoma Corydalis 1 ~ 4 and Radix Salviae Miltiorrhizae 3 ~ 5.
According to the Chinese medicine preparation of above-mentioned treatment peripheral vascular disease, it is made up of following raw material: Radix Gentianae Macrophyllae 16, Lignum Sappan
10, Radix Notoginseng 6, Radix Angelicae Sinensis 12, Cortex Moutan 9, Radix Et Rhizoma Rhei 30, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 12, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 3.
The preparation method of a kind of Chinese medicine preparation treating peripheral vascular disease, specifically comprises the following steps that
(1) each pretreatment of raw material become 20 ~ 60 mesh powder standby；
(2) weigh each taste crude drug, boiling twice according to above-mentioned consumption proportion, add crude drug gross mass 8 ~ 10 for the first time
Times amount water, decocts 1.5～2h, and double gauze filters, and second time adds crude drug gross mass 4 ~ 6 times amount water, decocts 1～2h, filters, and closes
And twice filtrate, it is concentrated into 1/12～1/10 volume of the cumulative volume that adds water, the Chinese medicine preparation of peripheral vascular disease must be treated.
The pharmacology of each taste crude drug in Chinese medicine preparation of the present invention:
Radix Gentianae Macrophyllae: acrid in the mouth, hardship, cold nature.Return stomach warp, Liver Channel, gallbladder meridian.Effect rheumatism, relaxing muscles and tendons network, clearind deficient heat.For rheumatism numbness
Bitterly, muscle arteries and veins contracture, joint aches, afternoon fever, and infantile malnutrition generates heat.
Lignum Sappan: sweet in the mouth, salty, flat.GUIXIN, liver, spleen channel.Effect promoting the circulation of blood blood stasis dispelling, reducing swelling and alleviating pain.For amenorrhea dysmenorrhea, puerperal
Stasis blocking, chest and abdomen twinge, wound swells and ache.
Radix Notoginseng: sweet in the mouth, micro-hardship, warm in nature.Return Liver Channel, stomach warp, heart channel, lung meridian, large intestine channel.Having dissipating blood stasis hemostasis, detumescence is fixed
Effect of pain.Cure mainly spitting of blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen twinge, tumbling down swells and ache.
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature.Return liver, the heart, spleen channel.Effect is enriched blood, is invigorated blood circulation, menstruction regulating and pain relieving, moisturize laxation.Main
Control all cards of blood deficiency；Menoxenia；Amenorrhea；Dysmenorrhea；Lump in the abdomen knot is poly-；Metrorrhagia；Asthenia cold abdominalgia；Flaccidity syndrome and arthralgia syndrome；Numbness of the skin；Dryness of the intestine dyschezia；
Weight after bloody dysentery；Ulcer sores；Injury from falling down.
Cortex Moutan: bitter in the mouth, pungent, cold nature.GUIXIN, liver, kidney channel.There is the merits such as clearing away heat and cooling blood, activating blood circulation to dissipate blood stasis, reducing the asthenic fever
Effect.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases；Send out speckle；Tell nosebleed；Calentura later stage hot Fu Yin distributes heat；Deficiency of YIN osteopyrexia and fever；Amenorrhea due to stagnation of blood；Dysmenorrhea；
Carbuncle sore tumefacting virus；Fall and flutter the pain of injury；Beriberoid pyretic arthralgia.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return stomach warp, large intestine channel, Liver Channel, spleen channel.Effect heat and toxic materials clearing away, eliminating fire and detoxication, invigorate blood circulation and dispel
The stasis of blood, clearly let out damp and hot.Cure mainly: excess-heat constipation；The accumulation of heat feeling of stuffiness in chest；Damp-heat dysentery；Jaundice；Gonorrhea；Edema abdominal distention；Dysuria；Conjunctival congestion；
Laryngopharynx swelling and pain；Aphtha of the mouth and tongue；Gastropyretic vomiting；Spit blood；Spitting of blood；Epistaxis；Have blood in stool；Hematuria；Blood-retention；Amenorrhea；Puerperal the stagnant stomachache of the stasis of blood；Disease
Abdominal mass is gathered；Traumatic injury；Pyretic toxicity carbuncle and ulcer；Erysipelas；Scald.
Cortex Periplocae: acrid in the mouth, hardship.Return liver, kidney, heart channel.Function wind-damp dispelling, bone and muscle strengthening.For anemofrigid-damp arthralgia, soreness of the waist and knees,
Shortness of breath and palpitation, edema of lower limbs.
Radix Rehmanniae: sweet in the mouth, hardship, cold in nature.Enter the heart, liver, kidney channel.Effect clearing away heat and promoting production of body fluid, cool after, hemostasis；Hinder for hot blast
The moon, crimson tongue excessive thirst, speckle dermexanthesis, haematemesis, epistaxis, laryngopharynx swelling and pain.
Flos Carthami: acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Enter bladder, kidney channel.Effect is induced sweat, wind-damp dispelling；Cure mainly affection of exogenous wind-cold；Have a headache lossless；
Mimeograph cold-damp numbness；Edema due to wind pathogen edema；Sore swollen toxin.
Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature.Enter the heart, spleen, liver, lung.There are promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving.Each for whole body
Portion's qi depression to blood stasis pain, dysmenorrhea, amenorrhea, lump in the abdomen, postpartum stagnation, injury from falling down, hernia is had a pain.
Radix Salviae Miltiorrhizae: bitter in the mouth, is slightly cold, nontoxic.Enter the heart, Liver Channel.Having blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, removing heat from blood eliminating carbuncle
Effect.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, the accumulation of abdominal mass abdominal mass, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, dysmenorrhea amenorrhea, skin ulcer
Infections swells and ache.
The positive beneficial effect of the present invention:
(1) present invention is according to traditional Chinese medical science traditional theory, combines the long-term clinical practice of inventor, this medicine on the basis of group passes secret recipe
Selected raw material, compatibility is reasonable, and effect is complementary, can produce preferable synergism.Qi depression to blood stasis, meridians stasis blocking are to cause Peripheral blood
The important pathological process of pipe disease, clinical practice shows, Chinese medicine preparation of the present invention can be applicable to thromboangiitis obliterans, obturation
Property atherosclerosis, deep venous thrombosis of lower limbs, superficial thrombophlebitis, Raynaud disease etc. cure after do not rebound, curative effect
Consolidating, processing technology of the present invention saves the property of medicine of medicine, is greatly improved curative effect.
(2) present invention is pure tcm product, safety, and medical expense is low, instant effect, and general 1 ~ 2 course for the treatment of takes effect, patient's pain
Bitter little, not drug resistance, toxic and side effects is little, is easily accepted by patients, it is to avoid heavy dose of use Western medicine produces the defect of toxic and side effects.
(3) Chinese medicine preparation of the present invention overcomes the situation of the poor effect treating at present these diseases, instant effect, good effect,
Easy to use, it is possible to real provides cost-effective help for extensive patients.
Usage and dosage
During use, take l00 ~ 150ml, add boiled water to 1000ml, fumigation and wash method affected part, every day 2 times, each 15 ~ 25 minutes.
Case is added up:
Thromboangiitis obliterans 190 example, male 86 example, women 104 example；Age of onset 21～65 years old；Within the course of disease 4 years
, wherein, 132 example within half a year, half a year～1 year 36 examples, 2～3 years 8 examples, 3～4 years 14 examples；Predisposing factors: have suction
Cigarette history 67 example, cold injury history 86 example, inducement fails to understand 37 examples.
Therapeutic outcome:
Therapeutic outcome is added up by the criterion of therapeutical effect drafted according to Pei Yukun " peripheral vessels ", and result is: rhomboembolia type
Vasculitis cures 60 examples, marked improvement 79 example, progressive 34 examples, invalid 17 examples, total effective rate 91.1%.
Detailed description of the invention:
Below in conjunction with embodiment to further description of the present invention, but it is not limiting as present disclosure.
Embodiment 1:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 10 ~ 20, Lignum Sappan 5 ~ 15,
Radix Notoginseng 2 ~ 8, Radix Angelicae Sinensis 5 ~ 15, Cortex Moutan 3 ~ 12, Radix Et Rhizoma Rhei 20 ~ 35, Cortex Periplocae 5 ~ 10, Radix Rehmanniae 5 ~ 10, Flos Carthami 5 ~ 15, Rhizoma Et Radix Notopterygii 1 ~
6, Rhizoma Corydalis 1 ~ 8 and Radix Salviae Miltiorrhizae 1 ~ 5.
The preparation method of the Chinese medicine preparation of above-mentioned treatment peripheral vascular disease, specifically comprises the following steps that
(1) each pretreatment of raw material become 20 ~ 60 mesh powder standby；
(2) weigh each taste crude drug, boiling twice according to above-mentioned consumption proportion, add crude drug gross mass 8 ~ 10 for the first time
Times amount water, decocts 1.5～2h, and double gauze filters, and second time adds crude drug gross mass 4 ~ 6 times amount water, decocts 1～2h, filters, and closes
And twice filtrate, it is concentrated into 1/12～1/10 volume of the cumulative volume that adds water, the Chinese medicine preparation of peripheral vascular disease must be treated.
Embodiment 2:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 16, Lignum Sappan 10, Radix Notoginseng 6,
Radix Angelicae Sinensis 12, Cortex Moutan 9, Radix Et Rhizoma Rhei 30, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 12, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 3:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 10, Lignum Sappan 15, Radix Notoginseng 2,
Radix Angelicae Sinensis 15, Cortex Moutan 3, Radix Et Rhizoma Rhei 35, Cortex Periplocae 5, Radix Rehmanniae 10, Flos Carthami 5, Rhizoma Et Radix Notopterygii 6, Rhizoma Corydalis 1 and Radix Salviae Miltiorrhizae 5.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 4:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 12, Lignum Sappan 14, Radix Notoginseng 3,
Radix Angelicae Sinensis 13, Cortex Moutan 4, Radix Et Rhizoma Rhei 32, Cortex Periplocae 7, Radix Rehmanniae 8, Flos Carthami 6, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 2 and Radix Salviae Miltiorrhizae 4.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 5:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 13, Lignum Sappan 13, Radix Notoginseng 4,
Radix Angelicae Sinensis 12, Cortex Moutan 5, Radix Et Rhizoma Rhei 30, Cortex Periplocae 8, Radix Rehmanniae 7, Flos Carthami 7, Rhizoma Et Radix Notopterygii 4, Rhizoma Corydalis 3 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 6:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 14, Lignum Sappan 12, Radix Notoginseng 5,
Radix Angelicae Sinensis 11, Cortex Moutan 6, Radix Et Rhizoma Rhei 28, Cortex Periplocae 9, Radix Rehmanniae 6, Flos Carthami 8, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 2.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 7:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 15, Lignum Sappan 10, Radix Notoginseng 6,
Radix Angelicae Sinensis 10, Cortex Moutan 7, Radix Et Rhizoma Rhei 25, Cortex Periplocae 10, Radix Rehmanniae 6.5, Flos Carthami 10, Rhizoma Et Radix Notopterygii 4.5, Rhizoma Corydalis 6 and Radix Salviae Miltiorrhizae 1.5.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 8:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 16, Lignum Sappan 9, Radix Notoginseng 7,
Radix Angelicae Sinensis 9, Cortex Moutan 8, Radix Et Rhizoma Rhei 23, Cortex Periplocae 8, Radix Rehmanniae 5, Flos Carthami 12, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 7 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 9:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 18, Lignum Sappan 7, Radix Notoginseng 8,
Radix Angelicae Sinensis 7, Cortex Moutan 10, Radix Et Rhizoma Rhei 21, Cortex Periplocae 9, Radix Rehmanniae 6, Flos Carthami 14, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 8 and Radix Salviae Miltiorrhizae 2.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 10:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 20, Lignum Sappan 5, Radix Notoginseng 8,
Radix Angelicae Sinensis 5, Cortex Moutan 12, Radix Et Rhizoma Rhei 20, Cortex Periplocae 10, Radix Rehmanniae 5, Flos Carthami 15, Rhizoma Et Radix Notopterygii 1, Rhizoma Corydalis 8 and Radix Salviae Miltiorrhizae 1.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 11:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 16, Lignum Sappan 8, Radix Notoginseng 8,
Radix Angelicae Sinensis 11, Cortex Moutan 9, Radix Et Rhizoma Rhei 26, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 12, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 2.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 12:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 11, Lignum Sappan 15, Radix Notoginseng 6,
Radix Angelicae Sinensis 9, Cortex Moutan 5, Radix Et Rhizoma Rhei 24, Cortex Periplocae 8, Radix Rehmanniae 9, Flos Carthami 12, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 6 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 13:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 17, Lignum Sappan 8, Radix Notoginseng 7, when
Return 14, Cortex Moutan 10, Radix Et Rhizoma Rhei 29, Cortex Periplocae 6, Radix Rehmanniae 8, Flos Carthami 10, Rhizoma Et Radix Notopterygii 4, Rhizoma Corydalis 2 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 14:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 19, Lignum Sappan 5, Radix Notoginseng 6, when
Return 12, Cortex Moutan 8, Radix Et Rhizoma Rhei 26, Cortex Periplocae 8, Radix Rehmanniae 5, Flos Carthami 15, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 6 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 15:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 13, Lignum Sappan 10, Radix Notoginseng 6,
Radix Angelicae Sinensis 8, Cortex Moutan 4, Radix Et Rhizoma Rhei 20, Cortex Periplocae 6, Radix Rehmanniae 8, Flos Carthami 12, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 5 and Radix Salviae Miltiorrhizae 5.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 16:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 18, Lignum Sappan 10, Radix Notoginseng 6,
Radix Angelicae Sinensis 7, Cortex Moutan 4, Radix Et Rhizoma Rhei 32, Cortex Periplocae 8, Radix Rehmanniae 7, Flos Carthami 13, Rhizoma Et Radix Notopterygii 4, Rhizoma Corydalis 3 and Radix Salviae Miltiorrhizae 4.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 17:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 19, Lignum Sappan 6, Radix Notoginseng 4, when
Return 12, Cortex Moutan 4, Radix Et Rhizoma Rhei 24, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 7, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 2.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 18:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 20, Lignum Sappan 8, Radix Notoginseng 5, when
Return 5, Cortex Moutan 10, Radix Et Rhizoma Rhei 23, Cortex Periplocae 6, Radix Rehmanniae 7, Flos Carthami 9, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 6 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 19:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 12, Lignum Sappan 11, Radix Notoginseng 4,
Radix Angelicae Sinensis 6, Cortex Moutan 10, Radix Et Rhizoma Rhei 24, Cortex Periplocae 7, Radix Rehmanniae 8, Flos Carthami 13, Rhizoma Et Radix Notopterygii 5, Rhizoma Corydalis 6 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 20:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 17, Lignum Sappan 9, Radix Notoginseng 7, when
Return 8, Cortex Moutan 10, Radix Et Rhizoma Rhei 27, Cortex Periplocae 9, Radix Rehmanniae 6, Flos Carthami 8, Rhizoma Et Radix Notopterygii 3, Rhizoma Corydalis 5 and Radix Salviae Miltiorrhizae 4.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 21:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 12, Lignum Sappan 12, Radix Notoginseng 6,
Radix Angelicae Sinensis 8, Cortex Moutan 9, Radix Et Rhizoma Rhei 22, Cortex Periplocae 8, Radix Rehmanniae 9, Flos Carthami 12, Rhizoma Et Radix Notopterygii 4, Rhizoma Corydalis 3 and Radix Salviae Miltiorrhizae 2.
The preparation method of the present embodiment is same as in Example 1.
Embodiment 22:
A kind of Chinese medicine preparation treating peripheral vascular disease, is made up of following raw material: Radix Gentianae Macrophyllae 18, Lignum Sappan 14, Radix Notoginseng 2,
Radix Angelicae Sinensis 15, Cortex Moutan 12, Radix Et Rhizoma Rhei 25, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 13, Rhizoma Et Radix Notopterygii 4, Rhizoma Corydalis 5 and Radix Salviae Miltiorrhizae 3.
The preparation method of the present embodiment is same as in Example 1.
Above example only in order to technical scheme to be described, is not intended to limit, although with reference to previous embodiment
The present invention is described in detail, it will be understood by those within the art that: it still can be to aforementioned each enforcement
Technical scheme described in example is modified, or wherein portion of techniques feature is carried out equivalent；And these amendment or
Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (5)
1. the Chinese medicine preparation treating peripheral vascular disease, it is characterised in that be made up of following raw material: Radix Gentianae Macrophyllae 10 ~
20, Lignum Sappan 5 ~ 15, Radix Notoginseng 2 ~ 8, Radix Angelicae Sinensis 5 ~ 15, Cortex Moutan 3 ~ 12, Radix Et Rhizoma Rhei 20 ~ 35, Cortex Periplocae 5 ~ 10, Radix Rehmanniae 5 ~ 10, red
Spend 5 ~ 15, Rhizoma Et Radix Notopterygii 1 ~ 6, Rhizoma Corydalis 1 ~ 8 and Radix Salviae Miltiorrhizae 1 ~ 5.
The Chinese medicine preparation for the treatment of peripheral vascular disease the most according to claim 1, it is characterised in that former by following weight portion
Material is made: Radix Gentianae Macrophyllae 10 ~ 15, Lignum Sappan 9 ~ 15, Radix Notoginseng 6 ~ 8, Radix Angelicae Sinensis 5 ~ 11, Cortex Moutan 3 ~ 7, Radix Et Rhizoma Rhei 25 ~ 35, Cortex Periplocae 5 ~ 8, life
Radix Rehmanniae 7 ~ 10, Flos Carthami 12 ~ 15, Rhizoma Et Radix Notopterygii 1 ~ 3, Rhizoma Corydalis 4 ~ 8 and Radix Salviae Miltiorrhizae 1 ~ 3.
The Chinese medicine preparation for the treatment of peripheral vascular disease the most according to claim 1, it is characterised in that former by following weight portion
Material is made: Radix Gentianae Macrophyllae 15 ~ 20, Lignum Sappan 5 ~ 9, Radix Notoginseng 2 ~ 6, Radix Angelicae Sinensis 11 ~ 15, Cortex Moutan 7 ~ 12, Radix Et Rhizoma Rhei 20 ~ 25, Cortex Periplocae 8 ~ 10,
Radix Rehmanniae 7 ~ 10, Flos Carthami 5 ~ 12, Rhizoma Et Radix Notopterygii 3 ~ 6, Rhizoma Corydalis 1 ~ 4 and Radix Salviae Miltiorrhizae 3 ~ 5.
The Chinese medicine preparation for the treatment of peripheral vascular disease the most according to claim 1, it is characterised in that former by following weight portion
Material is made: Radix Gentianae Macrophyllae 16, Lignum Sappan 10, Radix Notoginseng 6, Radix Angelicae Sinensis 12, Cortex Moutan 9, Radix Et Rhizoma Rhei 30, Cortex Periplocae 8, Radix Rehmanniae 6, Flos Carthami 12, Qiang
Work 5, Rhizoma Corydalis 4 and Radix Salviae Miltiorrhizae 3.
The preparation method of the Chinese medicine preparation for the treatment of peripheral vascular disease the most according to claim 1, it is characterised in that concrete
Step is as follows:
Each pretreatment of raw material become 20 ~ 60 mesh powder standby；
Weigh each taste crude drug, boiling twice according to above-mentioned consumption proportion, add crude drug gross mass 8 ~ 10 times for the first time
Amount water, decocts 1.5～2h, and double gauze filters, and second time adds crude drug gross mass 4 ~ 6 times amount water, decocts 1～2h, filters, and merges
Twice filtrate, is concentrated into 1/12～1/10 volume of the cumulative volume that adds water, must treat the Chinese medicine preparation of peripheral vascular disease.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114159530A (en) * | 2020-09-11 | 2022-03-11 | 鲁南制药集团股份有限公司 | Application of Mailuoshutong preparation in preparation of medicine for treating Raynaud syndrome |
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| CN102824608A (en) * | 2012-09-12 | 2012-12-19 | 山东省千佛山医院 | Externally used Chinese herba preparation for treating peripheral vascular disease |
| CN102895357A (en) * | 2012-10-30 | 2013-01-30 | 李学燕 | External Chinese medicinal preparation for treating peripheral vascular diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114159530A (en) * | 2020-09-11 | 2022-03-11 | 鲁南制药集团股份有限公司 | Application of Mailuoshutong preparation in preparation of medicine for treating Raynaud syndrome |
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