CN102824608A - Externally used Chinese herba preparation for treating peripheral vascular disease - Google Patents
Externally used Chinese herba preparation for treating peripheral vascular disease Download PDFInfo
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- CN102824608A CN102824608A CN2012103363046A CN201210336304A CN102824608A CN 102824608 A CN102824608 A CN 102824608A CN 2012103363046 A CN2012103363046 A CN 2012103363046A CN 201210336304 A CN201210336304 A CN 201210336304A CN 102824608 A CN102824608 A CN 102824608A
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Abstract
The invention discloses an externally used Chinese herba preparation for treating a peripheral vascular disease. The externally used Chinese herba preparation is prepared by the following bulk pharmaceutical chemicals in parts by weight: 3-10 parts of artemisia anomala, 9-15 parts of caulis spatholobi, 3-9 parts of sappanwood, 3-9 parts of notopterygium root, 3-30 parts of rheum officinale, 6-12 parts of angelica sinensis, 3-9 parts of ligusticum wallichii, 3-9 parts of safflower carthamus, 3-15 parts of rhizoma corydalis, 3-9 parts of rhizoma curcumae longae, and 3-9 parts of pseudo-ginseng. Through clinical verification, the externally used Chinese herba preparation for treating the peripheral vascular disease has a large application scope, can be used for treating thromboangiitis obliterans, atherosclerosis obliterans, lower extremity deep venous thrombosis, superficial thrombophlebitis, raynaud disease and the like, has quick effectiveness and a good curative effect, and is convenient to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine for outer use of treating peripheral vascular disease.
Background technology
Peripheral vascular disease is the common name of peripheral vascular disease; Mainly comprise thromboangiitis obliterans, occlusive atherosclerosis, deep venous thrombosis of lower limbs, superficial thrombophlebitis, Raynaud disease, Takayasu arteritis; And congestion swelling, stasis dermatitis, secondary infection due to the varicose veins of the lower extremity, dark venous valvular incompetence, erysipelas, elephatiasis etc.Though its pathogenic factor, pathological change and clinical characters are different, all there is the blood stasis general character, show as blood stasis, ischemia, ecchymosis, swelling, atheromatous plaque, thrombosis, angiostenosis or obturation, even ulcer or gangrene occur.Through the clinical practice of ancient Chinese medicine doctor at different times, development forms unique theoretical system and distinctive Therapeutic Method, has accumulated abundant clinical experience.
At present; The external therapy of peripheral vascular disease is more, have plaster to treat sand, enclose deposited therapy, dusting powder drug therapy, fomentation therapy etc., and fumigation-washing therapy is one of external therapy of using always; Peripheral vascular disease is treated in the ruling by law of invigorating blood circulation of application addiction; Have many-sided therapeutical effect, but the medicine that is used for fumigation-washing therapy in the prior art remains, cost more high defective undesirable at therapeutic effect, need a kind of therapeutic effect better medicament.
Summary of the invention
To above-mentioned prior art, the invention provides the Chinese medicine for outer use that a kind of therapeutic effect better is used to treat peripheral vascular disease.
The present invention realizes through following technical scheme:
A kind of Chinese medicine for outer use of treating peripheral vascular disease is formed/is processed by following bulk drugs: 3～10 parts of Herba Artemisiae Anomalaes, 9～15 parts of Caulis Spatholobis; 3～9 parts of Lignum Sappans, 3～9 parts of Rhizoma Et Radix Notopterygiis, 3～30 parts of Radix Et Rhizoma Rhei; 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Rhizoma Chuanxiongs, 3～9 parts on Flos Carthami; 3～15 parts of Rhizoma Corydalis, 3～9 parts in Rhizoma Curcumae Longae, 3～9 parts of Radix Notoginseng.
Preferably, form/process: 6～9 parts of Herba Artemisiae Anomalaes, 6～12 parts of Caulis Spatholobis, 4～6 parts of Lignum Sappans by following bulk drugs; 4～6 parts of Rhizoma Et Radix Notopterygiis, 10～20 parts of Radix Et Rhizoma Rhei, 7～9 parts of Radix Angelicae Sinensis, 4～7 parts of Rhizoma Chuanxiongs; 4～6 parts on Flos Carthami, 6～12 parts of Rhizoma Corydalis, 4～6 parts in Rhizoma Curcumae Longae, 4～6 parts of Radix Notoginseng.
Most preferred, form/process by following bulk drugs: 6 parts of Herba Artemisiae Anomalaes, 10 parts of Caulis Spatholobis, 6 parts of Lignum Sappans, 6 parts of Rhizoma Et Radix Notopterygiis, 12 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts on Flos Carthami, 9 parts of Rhizoma Corydalis, 6 parts in Rhizoma Curcumae Longae, 6 parts of Radix Notoginseng.
The Chinese medicine for outer use of treatment peripheral vascular disease of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional external preparation during preparation, for example can these crude drug be processed decoct, also can these crude drug be processed powder; Preferably process decoct, method for preparing is: press the consumption proportion weighting raw materials, decocte with water twice adds 8 times of amounts (weight multiple) water for the first time; Fry in shallow oil 1.5～2h, double gauze filters, and adds 6 times of amounts (weight multiple) water for the second time, fries in shallow oil 1～2h; Filter, merge filtrating twice, be concentrated into 1/12～1/10 volume that adds the water cumulative volume, promptly get the Chinese medicine for outer use of treating peripheral vascular disease; Leave standstill 24h, get supernatant, bottling; Shady and cool dry place is put in sealing, and is subsequent use.
The Chinese medicine for outer use of treatment peripheral vascular disease of the present invention during use, is got l00ml, adds boiled water to 1000ml, fumigation and wash method affected part, every day twice, each about 20 minutes.
The Chinese medicine for outer use of treatment peripheral vascular disease of the present invention, pharmacology analysis is following: think that according to the traditional Chinese medical science onset theory qi depression to blood stasis, meridian stasis resistance are the important pathological processes that causes peripheral vascular disease.Herba Artemisiae Anomalae removing blood stasis among the side of the present invention stimulates the menstrual flow eliminating stasis to stop pain.Caulis Spatholobi is enriched blood, and invigorates blood circulation collateral dredging.The Lignum Sappan promoting the circulation of blood is eliminated the phlegm, reducing swelling and alleviating pain.The Rhizoma Et Radix Notopterygii cold expelling dispels the wind, dehumidifying, pain relieving.The Radix Et Rhizoma Rhei purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.The Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Rhizoma Corydalis is used for pain of each qi depression to blood stasis of whole body.The circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia.The hemostasis of Radix Notoginseng dissipating blood stasis, subduing swelling and relieving pain.All medicines share, and the logical effect of invigorating blood circulation of temperature is arranged
The Chinese medicine for outer use of treatment peripheral vascular disease of the present invention has following effect:
1. kind blood circulation and microcirculation increase the LBF amount, improve local organization nutrition.
2. expand peripheral vessels, remove vasospasm.
3. have anticoagulant, antithrombotic and fibrinolysis activity.
4. blood fat reducing is disappeared with the promotion atheromatous plaque.
5. antiinflammatory is analgesic, promotes inflammation to absorb.
6. promote the softening of proliferative lesion and disappear.
7. promote tissue repair, make wound healing.
The Chinese medicine for outer use of treatment peripheral vascular disease of the present invention, through clinical verification, applied widely; Can be used for thromboangiitis obliterans, occlusive atherosclerosis, deep venous thrombosis of lower limbs, superficial thrombophlebitis, Raynaud disease etc.; Instant effect, good effect, easy to use.
The specific embodiment
Below in conjunction with embodiment and clinical data the present invention is further described.
A kind of Chinese medicine for outer use of treating peripheral vascular disease of embodiment 1 preparation
Prescription is: Herba Artemisiae Anomalae 600g, Caulis Spatholobi 1000g, Lignum Sappan 600g, Rhizoma Et Radix Notopterygii 600g, Radix Et Rhizoma Rhei 1200g, Radix Angelicae Sinensis 900g, Rhizoma Chuanxiong 600g, Flos Carthami 600g, Rhizoma Corydalis 900g, Rhizoma Curcumae Longae 600g, Radix Notoginseng 600g.
Method for preparing is: said medicine is mixed, and decocte with water twice adds 8 times of water gagings for the first time, fries in shallow oil 2h, and double gauze filters; For the second time add 6 times of water gagings, fry in shallow oil 2h, filter, merge filtrating twice; Be concentrated into 10000ml, leave standstill 24h, get supernatant, bottling; Every bottle is 200ml, and shady and cool dry place is put in sealing, and is subsequent use.
A kind of Chinese medicine for outer use of treating peripheral vascular disease of embodiment 2 preparations
Prescription is: Herba Artemisiae Anomalae 6g, Caulis Spatholobi 12g, Lignum Sappan 4g, Rhizoma Et Radix Notopterygii 6g, Radix Et Rhizoma Rhei 10g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 4g, Flos Carthami 6g, Rhizoma Corydalis 6g, Rhizoma Curcumae Longae 6g, Radix Notoginseng 4g.
Method for preparing is: said medicine is mixed, and decocte with water twice adds 8 times of water gagings for the first time, fries in shallow oil 2h, and double gauze filters, and adds 6 times of water gagings for the second time; Fry in shallow oil 2h, filter, merge filtrating twice, be concentrated into 100ml, promptly get; Leave standstill 24h, get supernatant, shady and cool dry place is put in sealing, and is subsequent use.
A kind of Chinese medicine for outer use of treating peripheral vascular disease of embodiment 3 preparations
Prescription is: Herba Artemisiae Anomalae 9g, Caulis Spatholobi 6g, Lignum Sappan 6g, Rhizoma Et Radix Notopterygii 4g, Radix Et Rhizoma Rhei 20g, Radix Angelicae Sinensis 7g, Rhizoma Chuanxiong 7g, Flos Carthami 4g, Rhizoma Corydalis 12g, Rhizoma Curcumae Longae 4g, Radix Notoginseng 6g.
Method for preparing is: said medicine is mixed, and decocte with water twice adds 8 times of water gagings for the first time, fries in shallow oil 2h, and double gauze filters, and adds 6 times of water gagings for the second time; Fry in shallow oil 2h, filter, merge filtrating twice, be concentrated into 100ml, promptly get; Leave standstill 24h, get supernatant, shady and cool dry place is put in sealing, and is subsequent use.
A kind of Chinese medicine for outer use of treating peripheral vascular disease of embodiment 4 preparations
Prescription is: Herba Artemisiae Anomalae 3g, Caulis Spatholobi 15g, Lignum Sappan 3g, Rhizoma Et Radix Notopterygii 9g, Radix Et Rhizoma Rhei 3g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 3g, Flos Carthami 9g, Rhizoma Corydalis 3g, Rhizoma Curcumae Longae 9g, Radix Notoginseng 3g.
Method for preparing is: said medicine is mixed, and decocte with water twice adds 8 times of water gagings for the first time, fries in shallow oil 2h, and double gauze filters, and adds 6 times of water gagings for the second time; Fry in shallow oil 2h, filter, merge filtrating twice, be concentrated into 100ml, promptly get; Leave standstill 24h, get supernatant, shady and cool dry place is put in sealing, and is subsequent use.
A kind of Chinese medicine for outer use of treating peripheral vascular disease of embodiment 5 preparations
Prescription is: Herba Artemisiae Anomalae 10g, Caulis Spatholobi 9g, Lignum Sappan 9g, Rhizoma Et Radix Notopterygii 3g, Radix Et Rhizoma Rhei 30g, Radix Angelicae Sinensis 6g, Rhizoma Chuanxiong 9g, Flos Carthami 3g, Rhizoma Corydalis 15g, Rhizoma Curcumae Longae 3g, Radix Notoginseng 9g.
Method for preparing is: said medicine is mixed, and decocte with water twice adds 8 times of water gagings for the first time, fries in shallow oil 2h, and double gauze filters, and adds 6 times of water gagings for the second time; Fry in shallow oil 2h, filter, merge filtrating twice, be concentrated into 100ml, promptly get; Leave standstill 24h, get supernatant, shady and cool dry place is put in sealing, and is subsequent use.
The clinical observation of clinical data Drug therapy peripheral vessels property of the present invention disease
Patient's data: following six groups of patients:
(1) thromboangiitis obliterans 140 examples, male's 62 examples, women's 78 examples; Age of onset 23～63 years old; The course of disease 4 years does not wait with interior, and wherein, half a year is with interior 100 examples, half a year～1 year 20 examples, 2～3 years l0 examples, 3～4 years 10 examples; Predisposing factors: smoking history 35 examples are arranged, cold injury history 52 examples, inducement is failed to understand 53 examples.According to the diagnostic criteria that surgery vasculitis Professional Committee of Chinese Chinese medicine association is drafted, I phases 100 example, II phases 22 example, III phase secondary 18 examples.
(2) superficial thrombophlebitis 210 examples, male's 120 examples, women's 90 examples; Age of onset 23～70 years old; The course of disease 6 months does not wait with interior, and wherein, 1 week is with interior 22 examples, 1～2 all 60 examples, 2 weeks～l month 78 examples, 1～2 month 24 example, 2～6 months 26 examples; Predisposing factors: varicosis history 46 examples, intravenous drip treatment history 40 examples, sombre wet environment occupational history 10 examples, inducement is failed to understand 114 examples.
(3) venous thrombosis 112 examples, male's 32 examples, women's 80 examples; Age of onset 26～63 years old; The course of disease 12 years does not wait with interior, and wherein, 1 year with interior 34 examples, 1～2 year 40 example, 2～3 years 26 examples, 12 examples more than 3 years; Predisposing factors: cesarean history 8 examples, inducement is failed to understand 104 examples.
(4) simple property varicosis 31 examples, male's 11 examples, women's 20 examples; Age of onset 37～61 years old; 1～2 year 10 example of the course of disease, 21 examples more than 10 years; Predisposing factors: occupational history 22 examples of standing for a long time, inducement is failed to understand 9 examples.
(5) arteriosclerosis obliterans l0 example, male's 3 examples, women's 7 examples; Age of onset 36～49 years old, 1～2 year 4 example, 2～3 years 2 examples, 4 examples more than 3 years; Predisposing factors is all not clear.
(6) Raynaud disease 8 examples are above women of 4O year, the course of disease 4 examples more than 1 year, 4 examples more than 3 years; The state of an illness increased the weight of history after menoxenia and cold stimulation were all arranged.
Therapeutic scheme: during use, get the medicine of l00ml embodiment 1 preparation, add boiled water to 1000ml, fumigation and wash method affected part, every day twice, each about 20 minutes.The treatment January after observe the curative effect.
Therapeutic outcome: the criterion of therapeutical effect according to Pei Yukun " peripheral vessels " drafts is added up therapeutic outcome, and the result is: thromboangiitis obliterans is cured 20 examples, marked improvement 52 examples, progressive 47 examples, invalid 21 examples.Superficial thrombophlebitis is cured 131 examples, produce effects 79 examples.Venous thrombosis produce effects 37 examples, effective 75 examples.Effective 10 examples of arteriosclerosis obliterans.Raynaud disease produce effects 4 examples, effective 4 examples.Simple property varicosis is all invalid.
Claims (4)
1. a Chinese medicine for outer use of treating peripheral vascular disease is characterized in that: formed/processed by following bulk drugs: 3～10 parts of Herba Artemisiae Anomalaes, 9～15 parts of Caulis Spatholobis; 3～9 parts of Lignum Sappans, 3～9 parts of Rhizoma Et Radix Notopterygiis, 3～30 parts of Radix Et Rhizoma Rhei; 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Rhizoma Chuanxiongs, 3～9 parts on Flos Carthami; 3～15 parts of Rhizoma Corydalis, 3～9 parts in Rhizoma Curcumae Longae, 3～9 parts of Radix Notoginseng.
2. a kind of Chinese medicine for outer use of treating peripheral vascular disease according to claim 1 is characterized in that: formed/processed by following bulk drugs: 6～9 parts of Herba Artemisiae Anomalaes, 6～12 parts of Caulis Spatholobis; 4～6 parts of Lignum Sappans, 4～6 parts of Rhizoma Et Radix Notopterygiis, 10～20 parts of Radix Et Rhizoma Rhei; 7～9 parts of Radix Angelicae Sinensis, 4～7 parts of Rhizoma Chuanxiongs, 4～6 parts on Flos Carthami; 6～12 parts of Rhizoma Corydalis, 4～6 parts in Rhizoma Curcumae Longae, 4～6 parts of Radix Notoginseng.
3. a kind of Chinese medicine for outer use of treating peripheral vascular disease according to claim 1 is characterized in that: formed/processed by following bulk drugs: 6 parts of Herba Artemisiae Anomalaes, 10 parts of Caulis Spatholobis; 6 parts of Lignum Sappans, 6 parts of Rhizoma Et Radix Notopterygiis, 12 parts of Radix Et Rhizoma Rhei; 9 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts on Flos Carthami; 9 parts of Rhizoma Corydalis, 6 parts in Rhizoma Curcumae Longae, 6 parts of Radix Notoginseng.
4. claim 1,2 or 3 described a kind of method for preparinies of treating the Chinese medicine for outer use of peripheral vascular disease, it is characterized in that: method for preparing is: press the consumption proportion weighting raw materials, twice of decocte with water; For the first time add 8 times of water gagings, fry in shallow oil 1.5～2h, double gauze filters; For the second time add 6 times of water gagings, fry in shallow oil 1～2h, filter; Merge filtrating twice, be concentrated into 1/12～1/10 volume that adds the water cumulative volume, promptly get the Chinese medicine for outer use of treating peripheral vascular disease.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610771A (en) * | 2013-12-13 | 2014-03-05 | 李轩辕 | External traditional Chinese medicine preparation for treating peripheral vascular disease |
| CN106266207A (en) * | 2016-11-14 | 2017-01-04 | 河南中医药大学 | A kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof |
Citations (3)
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| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
| CN101007124A (en) * | 2006-01-27 | 2007-08-01 | 杨晓松 | A traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and its preparation method |
| CN101244181A (en) * | 2008-03-24 | 2008-08-20 | 湖北金诺药业有限公司 | Plaster for bone paralysis with function of qufengshengshi, blood circulation activating and stasis removing, and removing the obstruction in the channels to relieve pain, and preparation thereof |
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2012
- 2012-09-12 CN CN201210336304.6A patent/CN102824608B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
| CN101007124A (en) * | 2006-01-27 | 2007-08-01 | 杨晓松 | A traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and its preparation method |
| CN101244181A (en) * | 2008-03-24 | 2008-08-20 | 湖北金诺药业有限公司 | Plaster for bone paralysis with function of qufengshengshi, blood circulation activating and stasis removing, and removing the obstruction in the channels to relieve pain, and preparation thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610771A (en) * | 2013-12-13 | 2014-03-05 | 李轩辕 | External traditional Chinese medicine preparation for treating peripheral vascular disease |
| CN106266207A (en) * | 2016-11-14 | 2017-01-04 | 河南中医药大学 | A kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof |
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| CN102824608B (en) | 2014-01-22 |
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