CN102824608B - Externally used Chinese herba preparation for treating peripheral vascular disease - Google Patents
Externally used Chinese herba preparation for treating peripheral vascular disease Download PDFInfo
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- CN102824608B CN102824608B CN201210336304.6A CN201210336304A CN102824608B CN 102824608 B CN102824608 B CN 102824608B CN 201210336304 A CN201210336304 A CN 201210336304A CN 102824608 B CN102824608 B CN 102824608B
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Abstract
The invention discloses an externally used Chinese herba preparation for treating a peripheral vascular disease. The externally used Chinese herba preparation is prepared by the following bulk pharmaceutical chemicals in parts by weight: 3-10 parts of artemisia anomala, 9-15 parts of caulis spatholobi, 3-9 parts of sappanwood, 3-9 parts of notopterygium root, 3-30 parts of rheum officinale, 6-12 parts of angelica sinensis, 3-9 parts of ligusticum wallichii, 3-9 parts of safflower carthamus, 3-15 parts of rhizoma corydalis, 3-9 parts of rhizoma curcumae longae, and 3-9 parts of pseudo-ginseng. Through clinical verification, the externally used Chinese herba preparation for treating the peripheral vascular disease has a large application scope, can be used for treating thromboangiitis obliterans, atherosclerosis obliterans, lower extremity deep venous thrombosis, superficial thrombophlebitis, raynaud disease and the like, has quick effectiveness and a good curative effect, and is convenient to use.
Description
Technical field
The present invention relates to a kind of Chinese medicine for outer use for the treatment of peripheral vascular disease.
Background technology
Peripheral vascular disease is the common name of peripheral vascular disease, mainly comprise thromboangiitis obliterans, occlusive atherosclerosis, deep venous thrombosis of lower limbs, superficial thrombophlebitis, Raynaud disease, Takayasu arteritis, and congestion swelling, stasis dermatitis, secondary infection due to varicose veins of the lower extremity, dark venous valvular incompetence, erysipelas, elephatiasis etc.Although its pathogenic factor, pathological change and clinical characters are different, all there is blood stasis general character, show as blood stasis, ischemia, ecchymosis, swelling, atheromatous plaque, thrombosis, angiostenosis or obturation, even there is ulcer or gangrene.Clinical practice through ancient Chinese medicine doctor at different times, development forms unique theoretical system and distinctive Therapeutic Method, has accumulated abundant clinical experience.
At present, the external therapy of peripheral vascular disease is more, there is plaster to treat sand, enclose dressing treatment method, dusting powder drug therapy, fomentation therapy etc., and fumigation-washing therapy is one of conventional external therapy, peripheral vascular disease is treated in the ruling by law of invigorating blood circulation of application addiction, there is many-sided therapeutical effect, but in prior art, the medicine for fumigation-washing therapy remains, cost more high defect undesirable at therapeutic effect, need the better medicine of a kind of therapeutic effect.
Summary of the invention
For above-mentioned prior art, the invention provides the Chinese medicine for outer use that a kind of therapeutic effect is better used for the treatment of peripheral vascular disease.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease, by the crude drug of following weight portion, form/make: 3～10 parts of Herba Artemisiae Anomalaes, 9～15 parts of Caulis Spatholobis, 3～9 parts of Lignum Sappans, 3～9 parts of Rhizoma Et Radix Notopterygiis, 3～30 parts of Radix Et Rhizoma Rhei, 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Rhizoma Chuanxiongs, 3～9 parts, Flos Carthami, 3～15 parts of Rhizoma Corydalis, 3～9 parts, Rhizoma Curcumae Longae, 3～9 parts of Radix Notoginseng.
Preferably, by the crude drug of following weight portion, form/make: 6～9 parts of Herba Artemisiae Anomalaes, 6～12 parts of Caulis Spatholobis, 4～6 parts of Lignum Sappans, 4～6 parts of Rhizoma Et Radix Notopterygiis, 10～20 parts of Radix Et Rhizoma Rhei, 7～9 parts of Radix Angelicae Sinensis, 4～7 parts of Rhizoma Chuanxiongs, 4～6 parts, Flos Carthami, 6～12 parts of Rhizoma Corydalis, 4～6 parts, Rhizoma Curcumae Longae, 4～6 parts of Radix Notoginseng.
Most preferred, by the crude drug of following weight portion, form/make: 6 parts of Herba Artemisiae Anomalaes, 10 parts of Caulis Spatholobis, 6 parts of Lignum Sappans, 6 parts of Rhizoma Et Radix Notopterygiis, 12 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts, Flos Carthami, 9 parts of Rhizoma Corydalis, 6 parts, Rhizoma Curcumae Longae, 6 parts of Radix Notoginseng.
The Chinese medicine for outer use for the treatment of peripheral vascular disease of the present invention, during preparation, can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional external preparation, for example these crude drug can be made to decoct, also these crude drug can be made to powder, preferably make decoct, preparation method is: press consumption proportion weighting raw materials, decoct with water twice, add for the first time 8 times of amounts (weight multiple) water, decoct 1.5～2h, double gauze filters, add for the second time 6 times of amounts (weight multiple) water, decoct 1～2h, filter, merge filtrate twice, be concentrated into 1/12～1/10 volume that adds water cumulative volume, must treat the Chinese medicine for outer use of peripheral vascular disease, standing 24h, get supernatant, bottling, sealing, put shady and cool dry place, standby.
The Chinese medicine for outer use for the treatment of peripheral vascular disease of the present invention, during use, gets l00ml, adds boiled water to 1000ml, fumigation and wash method affected part, every day twice, each about 20 minutes.
The Chinese medicine for outer use for the treatment of peripheral vascular disease of the present invention, pharmacology analysis is as follows: according to traditional Chinese medical science onset theory, think, qi depression to blood stasis, meridians stasis blocking are to cause the important pathological process of peripheral vascular disease.Herba Artemisiae Anomalae removing blood stasis in side of the present invention stimulates the menstrual flow, eliminating stasis to stop pain.Caulis Spatholobi is enriched blood, invigorates blood circulation, and dredging collateral.Lignum Sappan promoting the circulation of blood is eliminated the phlegm, reducing swelling and alleviating pain.Rhizoma Et Radix Notopterygii cold expelling, dispels the wind, dehumidifying, pain relieving.Radix Et Rhizoma Rhei purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Rhizoma Corydalis for each qi depression to blood stasis of whole body bitterly.The circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia.The hemostasis of Radix Notoginseng dissipating blood stasis, subduing swelling and relieving pain.All medicines share, and have the logical effect of invigorating blood circulation of temperature
The Chinese medicine for outer use for the treatment of peripheral vascular disease of the present invention, has following effect:
1. kind blood circulation and microcirculation, increase LBF amount, improves local organization nutrition.
2. expand peripheral vessels, remove vasospasm.
3. there is anticoagulant, antithrombotic and fibrinolysis activity.
4. blood fat reducing and promotion atheromatous plaque disappear.
5. antiinflammatory is analgesic, promotes inflammation to absorb.
6. promote the softening of proliferative lesion and disappear.
7. promote tissue repair, make wound healing.
The Chinese medicine for outer use for the treatment of peripheral vascular disease of the present invention, through clinical verification, applied widely, can be used for thromboangiitis obliterans, occlusive atherosclerosis, deep venous thrombosis of lower limbs, superficial thrombophlebitis, Raynaud disease etc., instant effect, good effect, easy to use.
The specific embodiment
Below in conjunction with embodiment and clinical data, the present invention is further illustrated.
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease of embodiment 1 preparation
Formula is: Herba Artemisiae Anomalae 600g, Caulis Spatholobi 1000g, Lignum Sappan 600g, Rhizoma Et Radix Notopterygii 600g, Radix Et Rhizoma Rhei 1200g, Radix Angelicae Sinensis 900g, Rhizoma Chuanxiong 600g, Flos Carthami 600g, Rhizoma Corydalis 900g, Rhizoma Curcumae Longae 600g, Radix Notoginseng 600g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decoct 2h, double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, be concentrated into 10000ml, standing 24h, gets supernatant, bottling, every bottle is 200ml, sealing, put shady and cool dry place, standby.
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease of embodiment 2 preparation
Formula is: Herba Artemisiae Anomalae 6g, Caulis Spatholobi 12g, Lignum Sappan 4g, Rhizoma Et Radix Notopterygii 6g, Radix Et Rhizoma Rhei 10g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 4g, Flos Carthami 6g, Rhizoma Corydalis 6g, Rhizoma Curcumae Longae 6g, Radix Notoginseng 4g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, be concentrated into 100ml, obtain, standing 24h, gets supernatant, and shady and cool dry place is put in sealing, standby.
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease of embodiment 3 preparation
Formula is: Herba Artemisiae Anomalae 9g, Caulis Spatholobi 6g, Lignum Sappan 6g, Rhizoma Et Radix Notopterygii 4g, Radix Et Rhizoma Rhei 20g, Radix Angelicae Sinensis 7g, Rhizoma Chuanxiong 7g, Flos Carthami 4g, Rhizoma Corydalis 12g, Rhizoma Curcumae Longae 4g, Radix Notoginseng 6g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, be concentrated into 100ml, obtain, standing 24h, gets supernatant, and shady and cool dry place is put in sealing, standby.
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease of embodiment 4 preparation
Formula is: Herba Artemisiae Anomalae 3g, Caulis Spatholobi 15g, Lignum Sappan 3g, Rhizoma Et Radix Notopterygii 9g, Radix Et Rhizoma Rhei 3g, Radix Angelicae Sinensis 12g, Rhizoma Chuanxiong 3g, Flos Carthami 9g, Rhizoma Corydalis 3g, Rhizoma Curcumae Longae 9g, Radix Notoginseng 3g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, be concentrated into 100ml, obtain, standing 24h, gets supernatant, and shady and cool dry place is put in sealing, standby.
A kind of Chinese medicine for outer use for the treatment of peripheral vascular disease of embodiment 5 preparation
Formula is: Herba Artemisiae Anomalae 10g, Caulis Spatholobi 9g, Lignum Sappan 9g, Rhizoma Et Radix Notopterygii 3g, Radix Et Rhizoma Rhei 30g, Radix Angelicae Sinensis 6g, Rhizoma Chuanxiong 9g, Flos Carthami 3g, Rhizoma Corydalis 15g, Rhizoma Curcumae Longae 3g, Radix Notoginseng 9g.
Preparation method is: said medicine is mixed, and decocts with water twice, adds for the first time 8 times of water gagings, decocts 2h, and double gauze filters, and adds for the second time 6 times of water gagings, decoct 2h, filter, merge filtrate twice, be concentrated into 100ml, obtain, standing 24h, gets supernatant, and shady and cool dry place is put in sealing, standby.
The clinical observation of clinical data Drug therapy peripheral vessels of the present invention disease
Patient's data: following six groups of patients:
(1) thromboangiitis obliterans 140 examples, male's 62 examples, women's 78 examples; Age of onset 23～63 years old; The course of disease 4 years with interior not etc., wherein, half a year is with interior 100 examples, half a year～1 year 20 examples, 2～3 years l0 examples, 3～4 years 10 examples; Predisposing factors: there are smoking history 35 examples, cold injury history 52 examples, inducement is failed to understand 53 examples.The diagnostic criteria of drafting according to surgery vasculitis Professional Committee of Chinese Chinese medicine association, I phases 100 example, II phases 22 example, III phase secondary 18 examples.
(2) superficial thrombophlebitis 210 examples, male's 120 examples, women's 90 examples; Age of onset 23～70 years old; The course of disease 6 months with interior not etc., wherein, 1 week with interior 22 examples, 1～2 week 60 example, 2 weeks～l month 78 examples, 1～2 month 24 example, 2～6 months 26 examples; Predisposing factors: varicosis history 46 examples, intravenous drip treatment history 40 examples, sombre wet environment occupational history 10 examples, inducement is failed to understand 114 examples.
(3) venous thrombosis 112 examples, male's 32 examples, women's 80 examples; Age of onset 26～63 years old; The course of disease 12 years with interior not etc., wherein, 1 year with interior 34 examples, 1～2 year 40 example, 2～3 years 26 examples, 3 years above 12 examples; Predisposing factors: cesarean history 8 examples, inducement is failed to understand 104 examples.
(4) pure varicosis 31 examples, male's 11 examples, women's 20 examples; Age of onset 37～61 years old; 1～2 year 10 example of the course of disease, 10 years above 21 examples; Predisposing factors: occupational history 22 examples of standing for a long time, inducement is failed to understand 9 examples.
(5) arteriosclerosis obliterans l0 example, male's 3 examples, women's 7 examples; Age of onset 36～49 years old, 1～2 year 4 example, 2～3 years 2 examples, 3 years above 4 examples; Predisposing factors is all not clear.
(6) Raynaud disease 8 examples, are above women of 4O year, 1 year above 4 example of the course of disease, 3 years above 4 examples; All there is aggravation history after menoxenia and cold stimulation.
Therapeutic scheme: during use, get the medicine of l00ml embodiment 1 preparation, add boiled water to 1000ml, fumigation and wash method affected part, every day twice, each about 20 minutes.Treatment January after observe the curative effect.
Therapeutic outcome: the criterion of therapeutical effect of drafting according to Pei Yukun " peripheral vessels " is added up therapeutic outcome, and result is: thromboangiitis obliterans is cured 20 examples, marked improvement 52 examples, progressive 47 examples, invalid 21 examples.Superficial thrombophlebitis is cured 131 examples, effective 79 examples.Effective 37 examples of venous thrombosis, effective 75 examples.Effective 10 examples of arteriosclerosis obliterans.Effective 4 examples of Raynaud disease, effective 4 examples.Pure varicosis is all invalid.
Claims (4)
1. a Chinese medicine for outer use for the treatment of peripheral vascular disease, it is characterized in that: be to be made by the crude drug of following weight portion: 3～10 parts of Herba Artemisiae Anomalaes, 9～15 parts of Caulis Spatholobis, 3～9 parts of Lignum Sappans, 3～9 parts of Rhizoma Et Radix Notopterygiis, 3～30 parts of Radix Et Rhizoma Rhei, 6～12 parts of Radix Angelicae Sinensis, 3～9 parts of Rhizoma Chuanxiongs, 3～9 parts, Flos Carthami, 3～15 parts of Rhizoma Corydalis, 3～9 parts, Rhizoma Curcumae Longae, 3～9 parts of Radix Notoginseng.
2. a kind of Chinese medicine for outer use for the treatment of peripheral vascular disease according to claim 1, it is characterized in that: be to be made by the crude drug of following weight portion: 6～9 parts of Herba Artemisiae Anomalaes, 6～12 parts of Caulis Spatholobis, 4～6 parts of Lignum Sappans, 4～6 parts of Rhizoma Et Radix Notopterygiis, 10～20 parts of Radix Et Rhizoma Rhei, 7～9 parts of Radix Angelicae Sinensis, 4～7 parts of Rhizoma Chuanxiongs, 4～6 parts, Flos Carthami, 6～12 parts of Rhizoma Corydalis, 4～6 parts, Rhizoma Curcumae Longae, 4～6 parts of Radix Notoginseng.
3. a kind of Chinese medicine for outer use for the treatment of peripheral vascular disease according to claim 1, it is characterized in that: be to be made by the crude drug of following weight portion: 6 parts of Herba Artemisiae Anomalaes, 10 parts of Caulis Spatholobis, 6 parts of Lignum Sappans, 6 parts of Rhizoma Et Radix Notopterygiis, 12 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Angelicae Sinensis, 6 parts of Rhizoma Chuanxiongs, 6 parts, Flos Carthami, 9 parts of Rhizoma Corydalis, 6 parts, Rhizoma Curcumae Longae, 6 parts of Radix Notoginseng.
4. a kind of preparation method for the treatment of the Chinese medicine for outer use of peripheral vascular disease described in claim 1,2 or 3, it is characterized in that: preparation method is: press consumption proportion weighting raw materials, decoct with water twice, add for the first time 8 times of water gagings, decoct 1.5～2h, double gauze filters, and adds for the second time 6 times of water gagings, decocts 1～2h, filter, merge filtrate twice, be concentrated into 1/12～1/10 volume that adds water cumulative volume, must treat the Chinese medicine for outer use of peripheral vascular disease.
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| CN103610771B (en) * | 2013-12-13 | 2015-04-22 | 李庆华 | External traditional Chinese medicine preparation for treating peripheral vascular disease |
| CN106266207A (en) * | 2016-11-14 | 2017-01-04 | 河南中医药大学 | A kind of Chinese medicine preparation treating peripheral vascular disease and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
| CN101007124A (en) * | 2006-01-27 | 2007-08-01 | 杨晓松 | A traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and its preparation method |
| CN101244181A (en) * | 2008-03-24 | 2008-08-20 | 湖北金诺药业有限公司 | Plaster for bone paralysis with function of qufengshengshi, blood circulation activating and stasis removing, and removing the obstruction in the channels to relieve pain, and preparation thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1122243A (en) * | 1995-08-16 | 1996-05-15 | 岳泰出 | Medicinal powder for eliminating embolism and invigorating blood circulation |
| CN101007124A (en) * | 2006-01-27 | 2007-08-01 | 杨晓松 | A traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and its preparation method |
| CN101244181A (en) * | 2008-03-24 | 2008-08-20 | 湖北金诺药业有限公司 | Plaster for bone paralysis with function of qufengshengshi, blood circulation activating and stasis removing, and removing the obstruction in the channels to relieve pain, and preparation thereof |
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