CN104606635A - Traditional Chinese medicine composition for treating retinal vein obstruction - Google Patents
Traditional Chinese medicine composition for treating retinal vein obstruction Download PDFInfo
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- CN104606635A CN104606635A CN201510034928.6A CN201510034928A CN104606635A CN 104606635 A CN104606635 A CN 104606635A CN 201510034928 A CN201510034928 A CN 201510034928A CN 104606635 A CN104606635 A CN 104606635A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating retinal vein obstruction. The traditional Chinese medicine composition is prepared from the following raw medicines in parts by weight: 10 to 20 parts of cortex moutan, 15 to 30 parts of radix salviae miltiorrhizae, 10 to 20 parts of radix rehmanniae, 5 to 15 parts of ligusticum wallichii, 15 to 35 parts of pollen typhae, 20 to 40 parts of eclipta alba, 5 to 15 parts of schizonepeta, 10 to 20 parts of radix curcumae, 10 to 20 parts of prunella vulgaris, 8 to 16 parts of gastrodia elata, 1 to 5 parts of pseudo-ginseng, 8 to 16 parts of medicinal cyathula root, 5 to 15 parts of lumbricus, 20 to 40 parts of radix puerariae, 5 to 15 parts of rheum officinale, 10 to 20 parts of astragalus membranaceus, 3 to 9 parts of leech, 10 to 30 parts of semen cassiae, 10 to 30 parts of leonurus, 5 to 15 parts of folium mori, 10 to 30 parts of semen sesami nigrum, 5 to 15 parts of Chinese wolfberries, and 5 to 15 parts of fried fructus gardenia. The traditional Chinese medicine composition has the effects of clearing away heat and purging pathogenic fire, cooling blood to stop bleeding, smoothing the liver and relieving depression, promoting blood circulation to remove blood stasis, and has an obvious effect on treating retinal vein obstruction; the effect is reliable, and the preparation is simple and convenient.
Description
Technical field
The present invention relates to a kind of medicinal preparation not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of the retinal vein occlusion.
Background technology
The retinal vein occlusion is more common optical fundus blood vessel disease, it is characterized in that the retina blood stasis of blood is stagnant, retinal hemorrhage and edema, visual deterioration centered by cardinal symptom, or a certain partial visual field defect, but morbidity can not show a candle to obstruction of artery like that sharply and seriously, generally still can reserve part vision, after central retinal vein occlusion: 3 ~ 4 months, can iris neovascularization be there is in the patient of about 5 ~ 20%, and secondary neovascular glaucoma.The cause of disease causing retina meridian and vessels obstruction has a variety of, as blood vessel wall pathological changes, blood viscosity increase and thrombosis etc.Generally for etiological treatment and thrombosis can be prevented and treated clinically, as reduced blood pressure and intraocular pressure, reduce blood viscosity, alleviating thrombosis and tissue edema, and promote absorption of hemorrhage.Within more than four months, having no improvement person through Drug therapy can adopt argon or krypton ion laser to irradiate.There is the deficiency that Drug therapy curative effect is undesirable, laser radiation has a big risk in it.
The traditional Chinese medical science is thought, the retinal vein occlusion is many because of excessive rising of liver-YANG, upward invasion of liver-QI; Or stagnation of QI due to depression of the liver, the blood stasis of blood is stagnant; Or expectorant Re Neisheng, upper heap soil or fertilizer over and around the roots order key; Or overabundant liver-fire, above attack in order; Or hyperactivity of fire caused by deficiency of YIN, above disturb key clearly, cause order median nexus obstruction and send out as primary disease.
According to theory of Chinese medical science, for the pathogeny of the retinal vein occlusion, with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling for the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The deficiency that existing Drug therapy clinically treatment retinal vein occlusion curative effect is undesirable in order to overcome, laser radiation has a big risk, the invention provides a kind ofly to prepare conveniently, medicine source is wide, cost is low, evident in efficacy, reliable effect, the Chinese medicine composition of the treatment retinal vein occlusion that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of the retinal vein occlusion, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Radix Rehmanniae 10-20 part, Rhizoma Chuanxiong 5-15 part, Pollen Typhae 15-35 part, Herba Ecliptae 20-40 part, Herba Schizonepetae 5-15 part, Radix Curcumae 10-20 part, Spica Prunellae 10-20 part, Rhizoma Gastrodiae 8-16 part, Radix Notoginseng 1-5 part, Radix Cyathulae 8-16 part, Pheretima 5-15 part, Radix Puerariae 20-40 part, Radix Et Rhizoma Rhei 5-15 part, Radix Astragali 10-20 part, Hirudo 3-9 part, Semen Cassiae 10-30 part, Herba Leonuri 10-30 part, Folium Mori 5-15 part, Semen Sesami Nigrum 10-30 part, Fructus Lycii 5-15 part, Fructus Gardeniae (parched) 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of the retinal vein occlusion, is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 15 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Rehmanniae 15 parts, Rhizoma Chuanxiong 10 parts, Pollen Typhae 25 parts, Herba Ecliptae 30 parts, Herba Schizonepetae 10 parts, Radix Curcumae 15 parts, Spica Prunellae 15 parts, 12 parts, Rhizoma Gastrodiae, Radix Notoginseng 3 parts, Radix Cyathulae 12 parts, Pheretima 10 parts, Radix Puerariae 30 parts, Radix Et Rhizoma Rhei 10 parts, the Radix Astragali 15 parts, Hirudo 6 parts, Semen Cassiae 20 parts, Herba Leonuri 20 parts, 10 parts, Folium Mori, Semen Sesami Nigrum 20 parts, Fructus Lycii 10 parts, Fructus Gardeniae (parched) 10 parts.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Radix Salviae Miltiorrhizae has effect of promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind; Radix Rehmanniae has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Pollen Typhae has effect of hemostasis, blood stasis dispelling, diuresis; Herba Ecliptae has effect of liver-nourishing kidney-boosting, cooling blood for hemostasis; Herba Schizonepetae has the loose wind that induces sweat, effect of rash, the skin ulcer that disappears, hemostasis; Radix Curcumae has effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Spica Prunellae has effect of liver heat removing and eyesight improving, clearing away heat and promoting diuresis, mass dissipating and swelling eliminating; Rhizoma Gastrodiae has effect of endogenous wind stopping relieving convulsion, suppressing the hyperactive liver and subsiding YANG, dispelling wind and removing obstruction in the collateral; Radix Notoginseng has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain; Radix Cyathulae has effect of eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome; Pheretima has effect of clearing heat for calming endogenous wind, lung-clearing asthma-relieving, inducing diuresis for treating stranguria syndrome, current meridians; Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Radix Et Rhizoma Rhei has effect of pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, blood stasis dispelling cough-relieving; The Radix Astragali has effect that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling fortune is malicious; Hirudo has promoting blood circulation and breaking stagnation, the effect of the removing food stagnancy that stimulates the menstrual flow; Semen Cassiae has clearing away heat to improve acuity of vision, effect of loosening bowel to relieve constipation; Herba Leonuri has effect of promoting blood flow to regulate menstruation, blood stasis dispelling diuretic, heat-clearing and toxic substances removing; Folium Mori have effect of dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing liver-YANG, liver heat removing and eyesight improving, cooling blood for hemostasis; Semen Sesami Nigrum has invigorating the liver and kidney, moistening five ZANG-organs, physical strength profiting, longue meat, fills out effects of brains; Fructus Lycii has effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Fructus Gardeniae (parched) has effect of pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Drug component in the present composition, through dialectical compatibility, complements each other using, has synergism, play effect of clearing away heat-fire, cooling blood for hemostasis, soothing liver-QI for relieving depression, blood circulation promoting and blood stasis dispelling altogether, the retinal vein occlusion is reached to the object for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, do not occur toxic and side effects, total effective rate 91.4%, cure rate reaches 67.1%.
Detailed description of the invention
Below in conjunction with embodiment to the affected step explanation of the present invention.
Embodiment 1
Treat a Chinese medicine composition for the retinal vein occlusion, its raw material of Chinese medicine and weight proportion are: Cortex Moutan 15g, Radix Salviae Miltiorrhizae 20g, Radix Rehmanniae 15g, Rhizoma Chuanxiong 10g, Pollen Typhae 25g, Herba Ecliptae 30g, Herba Schizonepetae 10g, Radix Curcumae 15g, Spica Prunellae 15g, Rhizoma Gastrodiae 12g, Radix Notoginseng 3g, Radix Cyathulae 12g, Pheretima 10g, Radix Puerariae 30g, Radix Et Rhizoma Rhei 10g, Radix Astragali 15g, Hirudo 6g, Semen Cassiae 20g, Herba Leonuri 20g, Folium Mori 10g, Semen Sesami Nigrum 20g, Fructus Lycii 10g, Fructus Gardeniae (parched) 10g.
Embodiment 2
Treat a Chinese medicine composition for the retinal vein occlusion, its raw material of Chinese medicine and weight proportion are: Cortex Moutan 10g, Radix Salviae Miltiorrhizae 30g, Radix Rehmanniae 10g, Rhizoma Chuanxiong 15g, Pollen Typhae 15g, Herba Ecliptae 40g, Herba Schizonepetae 5g, Radix Curcumae 20g, Spica Prunellae 10g, Rhizoma Gastrodiae 16g, Radix Notoginseng 1g, Radix Cyathulae 16g, Pheretima 5g, Radix Puerariae 40g, Radix Et Rhizoma Rhei 5g, Radix Astragali 20g, Hirudo 3g, Semen Cassiae 30g, Herba Leonuri 10g, Folium Mori 15g, Semen Sesami Nigrum 10g, Fructus Lycii 15g, Fructus Gardeniae (parched) 5g.
Embodiment 3
Treat a Chinese medicine composition for the retinal vein occlusion, its raw material of Chinese medicine and weight proportion are: Cortex Moutan 20g, Radix Salviae Miltiorrhizae 10g, Radix Rehmanniae 20g, Rhizoma Chuanxiong 5g, Pollen Typhae 35g, Herba Ecliptae 20g, Herba Schizonepetae 15g, Radix Curcumae 10g, Spica Prunellae 20g, Rhizoma Gastrodiae 8g, Radix Notoginseng 5g, Radix Cyathulae 8g, Pheretima 15g, Radix Puerariae 20g, Radix Et Rhizoma Rhei 15g, Radix Astragali 10g, Hirudo 9g, Semen Cassiae 10g, Herba Leonuri 30g, Folium Mori 5g, Semen Sesami Nigrum 30g, Fructus Lycii 5g, Fructus Gardeniae (parched) 15g.
Embodiment 4
Treat a Chinese medicine composition for the retinal vein occlusion, its raw material of Chinese medicine and weight proportion are: Cortex Moutan 20g, Radix Salviae Miltiorrhizae 15g, Radix Rehmanniae 20g, Rhizoma Chuanxiong 5g, Pollen Typhae 30g, Herba Ecliptae 20g, Herba Schizonepetae 15g, Radix Curcumae 10g, Spica Prunellae 20g, Rhizoma Gastrodiae 8g, Radix Notoginseng 5g, Radix Cyathulae 8g, Pheretima 15g, Radix Puerariae 20g, Radix Et Rhizoma Rhei 15g, Radix Astragali 10g, Hirudo 9g, Semen Cassiae 15g, Herba Leonuri 25g, Folium Mori 5g, Semen Sesami Nigrum 25g, Fructus Lycii 5g, Fructus Gardeniae (parched) 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decoct, and decocts 15 ~ 20 minutes after water boils.Twice decoction is removed slag extracting juice, merges.
The present invention, with a kind of Chinese medicine composition for the treatment of the retinal vein occlusion given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 70 example, wherein man 30 example, female 40 example, 20 ~ 60 years old age.The shortest person of the course of disease 3 months, most elder reaches 3 years, average 1 year.
Two, diagnostic criteria:
1, the medical history of patient, has hypertension, diabetic history patient will strengthen examination of ocular fundus;
2, visual deterioration, as involved macula area vision light sensation, even blind;
3, venous engorgement, aubergine, retinal edema, large stretch of hemorrhage radially, flamboyancy or round shape, and adularescent cotton wool exudate, the hemorrhage vitreous body that enters causes muddiness; During as branch's thromboembolism, hemorrhage only for domination position.Papilloedema, edge blurry, there is ecchymosis on surface;
4, connective tissue proliferation and new vessels can be formed after hemorrhage and exudate absorption, cause proliferative retinopathy and secondary glaucoma;
, there is delayed filling and blood vessel Fluorescein Leakage in angiographic procedure, sometimes can find choke point in 5, fluoroscopic visualization.Peripheral veins visible fluorescence seepage, venous perfusion is slow or incomplete, and hemorrhage district fluorescence hides, and late period can occur Doppler flow mapping.
Three, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice is about 300ml, and point early, late twice half an hour ante cibum warmly take.It within 6 days, is a course for the treatment of.Period in a medicine is avoided eating anything raw or cold, pungent thing.
Four, criterion of therapeutical effect:
1, cure: optical fundus blood circulation improves, retinal hemorrhage basic absorption, and vision is promoted;
2, take a turn for the better: retinal hemorrhage partially absorbs, and vision slightly takes a turn for the better;
3, do not heal: sings and symptoms is without significant change.
Five, therapeutic effect: in this clinical observation case, takes medicine 3-10 the course for the treatment of, cures 47 examples, and take a turn for the better 17 examples, and do not heal 6 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1: Liu, man, 69 years old.Suddenly there is vision and drop to and only can distinguish manual in patient's readme, the congested and mild swelling of nipple is looked on optical fundus on inspection, and color is red, obscurity boundary; Retinal vein blood stream stasis, color is purple dark; Retinal vein caliber is irregular, significantly expands, in sausage shape; Whole optical fundus is abound with the retinal hemorrhage speckle differed in size.Be diagnosed as: the retinal vein occlusion.After 2 courses for the treatment of of medicament of taking prepared by Chinese medicine composition of the present invention, retinal hemorrhage major part absorbs, and vision is clearly better, after continuing to take 4 courses for the treatment of of prepared by Chinese medicine composition of the present invention medicament, retinal hemorrhage basic absorption, the recovery of excellent of vision, cures.
Case 2: chapter, female, 51 years old, patient's readme blurred vision, vision obviously went down.The treating serious edema caused hyperemia of the visible optic disc of examination of ocular fundus, obscurity boundary is also covered by hemorrhage, macular area can have obvious edema swell and hemorrhage, vein level expand tortuous as sausage shape.Be diagnosed as: the retinal vein occlusion.After 3 courses for the treatment of of medicament of taking prepared by Chinese medicine composition of the present invention, retinal hemorrhage partially absorbs, and vision slightly takes a turn for the better; Continue after taking 5 courses for the treatment of, optical fundus blood circulation improves, retinal hemorrhage basic absorption, normal visual acuity, recovery from illness.
Claims (2)
1. treat the Chinese medicine composition of the retinal vein occlusion for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 10-20 part, Radix Salviae Miltiorrhizae 15-30 part, Radix Rehmanniae 10-20 part, Rhizoma Chuanxiong 5-15 part, Pollen Typhae 15-35 part, Herba Ecliptae 20-40 part, Herba Schizonepetae 5-15 part, Radix Curcumae 10-20 part, Spica Prunellae 10-20 part, Rhizoma Gastrodiae 8-16 part, Radix Notoginseng 1-5 part, Radix Cyathulae 8-16 part, Pheretima 5-15 part, Radix Puerariae 20-40 part, Radix Et Rhizoma Rhei 5-15 part, Radix Astragali 10-20 part, Hirudo 3-9 part, Semen Cassiae 10-30 part, Herba Leonuri 10-30 part, Folium Mori 5-15 part, Semen Sesami Nigrum 10-30 part, Fructus Lycii 5-15 part, Fructus Gardeniae (parched) 5-15 part.
2. a kind of Chinese medicine composition for the treatment of the retinal vein occlusion according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 15 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Rehmanniae 15 parts, Rhizoma Chuanxiong 10 parts, Pollen Typhae 25 parts, Herba Ecliptae 30 parts, Herba Schizonepetae 10 parts, Radix Curcumae 15 parts, Spica Prunellae 15 parts, 12 parts, Rhizoma Gastrodiae, Radix Notoginseng 3 parts, Radix Cyathulae 12 parts, Pheretima 10 parts, Radix Puerariae 30 parts, Radix Et Rhizoma Rhei 10 parts, the Radix Astragali 15 parts, Hirudo 6 parts, Semen Cassiae 20 parts, Herba Leonuri 20 parts, 10 parts, Folium Mori, Semen Sesami Nigrum 20 parts, Fructus Lycii 10 parts, Fructus Gardeniae (parched) 10 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105031130A (en) * | 2015-08-25 | 2015-11-11 | 何萍萍 | Traditional Chinese medicine for treating central retinal vein occlusion |
| CN107412465A (en) * | 2017-05-25 | 2017-12-01 | 马玉玲 | A kind of inhibitor of retinal disorder |
| CN110624080A (en) * | 2019-10-31 | 2019-12-31 | 张铭连 | Pharmaceutical composition for treating intraocular hemorrhagic diseases with blood heat stasis |
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2015
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| CN1850244A (en) * | 2006-03-06 | 2006-10-25 | 王明扬 | Chinese medicine composition for treating eye disease and preparing method |
| CN102973748A (en) * | 2011-09-05 | 2013-03-20 | 魏加珍 | Chinese patent medicine granules for treating eyeground macular edema |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031130A (en) * | 2015-08-25 | 2015-11-11 | 何萍萍 | Traditional Chinese medicine for treating central retinal vein occlusion |
| CN107412465A (en) * | 2017-05-25 | 2017-12-01 | 马玉玲 | A kind of inhibitor of retinal disorder |
| CN110624080A (en) * | 2019-10-31 | 2019-12-31 | 张铭连 | Pharmaceutical composition for treating intraocular hemorrhagic diseases with blood heat stasis |
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Application publication date: 20150513 |