CN102961696A - Chinese medicinal composition for treating diabetic nephropathy edema - Google Patents
Chinese medicinal composition for treating diabetic nephropathy edema Download PDFInfo
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- CN102961696A CN102961696A CN2012103585569A CN201210358556A CN102961696A CN 102961696 A CN102961696 A CN 102961696A CN 2012103585569 A CN2012103585569 A CN 2012103585569A CN 201210358556 A CN201210358556 A CN 201210358556A CN 102961696 A CN102961696 A CN 102961696A
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Abstract
The invention relates to a Chinese medicinal composition for treating diabetic nephropathy edema. The composition is composed of the following Chinese herbal materials by weight: 6-18 parts of acontum fischeri, 10-20 parts of Poria cocos, 6-18 parts of Radix Paeoniae Alba, 6-18 parts of dried ginger, 20-40 parts of Chinese wax gourd peel, 20-40 parts of adsuki beans, 10-30 parts of Plantain Seeds, 10-30 parts of Astragalus, 10-20 parts of Chinese yam, and 10-20 parts of rhizoma atractylodis macrocephalae. The Chinese medicinal composition provided in the invention has the efficacy of diffusing lung to dissipate watery phlegm, tonifying spleen and strengthening kidney, clearing heat and toxic materials, promoting the circulation of qi to induce diuresis, and dispersing edema. With significant treatment effects on diabetic nephropathy edema and reliable functions, the composition involved in the invention has the characteristics of wide medicinal herb source, simple preparation, and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of medicinal preparation of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema.
Background technology
Diabetic nephropathy generation edema is because the urine of diabetic nephropathy patients undergoing can't excrete, and accumulation causes in vivo.Therefore, diabetic nephropathy patients undergoing the most important thing is to eliminate edema.The pathogenic factor of diabetic nephropathy edema has multiple: one, and after diabetes caused nephropathy, two renal blood flow groundwater increments can reduce, excess of the kidney matter ischemia, anoxia, and renin secretion increases; They are two years old, diabetic nephropathy patients undergoing urine is when suffering from kidney disease, along with the spilling gradually of aggravation albumen of the state of an illness increased, the albuminuria long-term existence also increases the weight of the damage of kidney day by day, form hypoproteinemia, plasma colloid osmotic pressure is reduced, and extracellular fluid is trapped in interstice, causes edema; Its three because the permeability of the whole body capillary wall that the immunity of diabetic nephropathy patients undergoing health infringement causes causes the moisture in the blood plasma to ooze the edema that causes to interstice.
The method for the treatment of diabetic nephropathy edema has much now, and wherein mainly be divided into doctor trained in Western medicine and the traditional Chinese medical science: western medical treatment diabetic nephropathy edema mainly is to carry out symptomatic treatment, and by the treatment of Western medicine, the diabetic nephropathy edema can be alleviated to some extent very soon, easily recurrence after the drug withdrawal.The TCM treatment of diabetes nephrotic edema is opposite with doctor trained in Western medicine, Chinese traditional treatment is to start with from " source of disease " (diabetic nephropathy): answer clearing away heat-damp and promoting diuresis during the Chinese traditional treatment of diabetic nephropathy edema, blood circulation promoting and blood stasis dispelling, in Primary Care (comprising control blood glucose, treatment hypertension, low-salt high-quality low protein diet), the rational Application Qingrejiedulishi therapy, can eliminate and alleviate damp and hot heresy, suppress the reaction of kidney immune inflammation, for reducing albuminuria, promote the reparation of nephropathy, and then improve renal function, the progress of control primary disease has positive effect.
The traditional Chinese medical science thinks that diabetic nephropathy divides 3 histological type, i.e. deficiency of both QI and YIN syndrome of blood stasis, deficiency of YANG QI syndrome of blood stasis, deficiency of both YIN and YANG syndrome of blood stasis, and the whole course of disease is running through the pathogenesis of channels stasis blocking all the time.The traditional Chinese medical science uses warming middle-JIAO and strengthening the spleen, promoting the circulation of QI to induce diuresis, lung qi dispersing to reinforce the kidney and be the Therapeutic Principle, to alleviate the kidney microangiopathies, recovers the blood capillary normal function.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind ofly prepare conveniently, the medicine source is wide, cost is low, evident in efficacy, reliable effect, a kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema of having no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Radix Aconiti Lateralis Preparata 6-18 part, Poria 10-20 part, Radix Paeoniae Alba 6-18 part, Rhizoma Zingiberis 6-18 part, Exocarpium Benincasae 20-40 part, Semen Phaseoli 20-40 part, Semen Plantaginis 10-30 part, Radix Astragali 10-30 part, Rhizoma Dioscoreae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 12 parts of Radix Aconiti Lateralis Preparatas, 15 parts in Poria, 12 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Zingiberiss, 30 parts of Exocarpium Benincasaes, 30 parts of Semen Phaseolis, 20 parts of Semen Plantaginiss, 20 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In the Chinese medicine composition of the present invention: Radix Aconiti Lateralis Preparata has recuperating depleted YANG and rescuing the patient from collapse, mends effect fiery supporing yang, dispersing cold for relieving pain; Poria has the effect in heat-clearing and toxic substances removing, damp eliminating diuretic, strengthening the spleen and stomach, sharp joint; The Radix Paeoniae Alba has the effect of nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing receipts antiperspirant; Rhizoma Zingiberis has that warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, the effect of warming the lung to resolve fluid-retention; Exocarpium Benincasae has the effect of promoting diuresis to clear away damp pathogen; Semen Phaseoli has the effect of inducing diuresis to remove edema, removing toxic substances and promoting pus discharge; The effect of Semen Plantaginis relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; The Radix Astragali has that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating take off admittedly, the effect of wind dispelling fortune poison; Rhizoma Dioscoreae has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow that will is calmed the nerves, the effect of life lengthening; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis.Drug component in the present composition is through dialectical compatibility, complements each other using, and has synergism, plays altogether the effect of lung qi dispersing dissipating fluid-retention, spleen benefiting and strengthen kidney, heat-clearing and toxic substances removing, promoting the circulation of QI to induce diuresis, detumescence, the diabetic nephropathy edema reached the purpose for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, the medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the usefulness that is decocted in water for oral dose.Through the clinical practice checking, it is evident in efficacy, reliable effect, and the property of medicine is gentle, toxic and side effects do not occur, total effective rate 86.7%, cure rate reaches 57.8%.
The specific embodiment
The present invention will be further described below in conjunction with embodiment.
Embodiment 1
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, its raw material of Chinese medicine by following weight proportion forms: Radix Aconiti Lateralis Preparata 12g, Poria 15g, Radix Paeoniae Alba 12g, Rhizoma Zingiberis 12g, Exocarpium Benincasae 30g, Semen Phaseoli 30g, Semen Plantaginis 20g, Radix Astragali 20g, Rhizoma Dioscoreae 15g, Rhizoma Atractylodis Macrocephalae 15g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, its raw material of Chinese medicine by following weight proportion forms: Radix Aconiti Lateralis Preparata 6g, Poria 20g, Radix Paeoniae Alba 6g, Rhizoma Zingiberis 18g, Exocarpium Benincasae 20g, Semen Phaseoli 40g, Semen Plantaginis 10g, Radix Astragali 30g, Rhizoma Dioscoreae 10g, Rhizoma Atractylodis Macrocephalae 20g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, its raw material of Chinese medicine by following weight proportion forms: Radix Aconiti Lateralis Preparata 18g, Poria 10g, Radix Paeoniae Alba 18g, Rhizoma Zingiberis 6g, Exocarpium Benincasae 40g, Semen Phaseoli 20g, Semen Plantaginis 30g, Radix Astragali 10g, Rhizoma Dioscoreae 20g, Rhizoma Atractylodis Macrocephalae 10g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, its raw material of Chinese medicine by following weight proportion forms: Radix Aconiti Lateralis Preparata 10g, Poria 18g, Radix Paeoniae Alba 10g, Rhizoma Zingiberis 15g, Exocarpium Benincasae 25g, Semen Phaseoli 35g, Semen Plantaginis 15g, Radix Astragali 25g, Rhizoma Dioscoreae 13g, Rhizoma Atractylodis Macrocephalae 17g.
Embodiment 5
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, its raw material of Chinese medicine by following weight proportion forms: Radix Aconiti Lateralis Preparata 16g, Poria 12g, Radix Paeoniae Alba 16g, Rhizoma Zingiberis 10g, Exocarpium Benincasae 35g, Semen Phaseoli 25g, Semen Plantaginis 25g, Radix Astragali 15g, Rhizoma Dioscoreae 18g, Rhizoma Atractylodis Macrocephalae 13g.
Chinese medicine composition in embodiment of the invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soaked 15～20 minutes, add water again and do not have about 8 centimetres of powder, carry out decocting the first time.Adopt intense fire to decoct at a simmer, it is rear with slow fire boiling 20～30 minutes to boil; Decoct for the second time, add water and do not have about 6 centimetres of powder, the water rear decoction 15～20 minutes of boiling.Twice decoction extracting juice that removes slag merges.
A kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to observe case 45 examples, male 31 examples wherein, women 14 examples, age 40-83 year.Course of disease 3-5.
Two, diagnosis basis:
(1), suffers from diabetes, hydrosarca;
(2), the phenomenon that anemia occurs;
(3), diabetic nephropathy also diabetic renal papillary necrosis can occur in early days.
Three, usage and dosage: during clinical practice, the component in the compositions, consumption are taken the circumstances into consideration increase and decrease according to patient's body weight, age and symptom.10 days is a course for the treatment of, one day potion, the about 300ml of twice extracting juice of decocting, minute morning, late twice warm taking.
Four, criterion of therapeutical effect:
(1), cure: transference cure, lab testing are repeatedly normal;
(2), take a turn for the better: cardinal symptom and relevant lab testing are improved;
(3), do not heal: symptom and lab testing are unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 3-10 the course for the treatment of 26 examples of fully recovering, 13 examples that take a turn for the better, invalid 6 examples.Toxic and side effects does not occur during the treatment.
Six, model case:
Case 1:
High certain, the woman, 68 years old, suffer from diabetic nephropathy for many years, constipation appears in the recent period, xerostomia wish drink, hydrosarca.Red tongue with yellow fur, rolling pulse is strong.Take 3 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, edema disappears.Defecation is normal after continuing to take 2 courses for the treatment of, and thirsty sense alleviates to normally.
Case 2:
Chen, the man, 61 years old, suffer from diabetic nephropathy, urinary micturition mixes such as fat, has a dizzy spell, tinnitus, blurred vision, dry mouth with parched lips, it is vexed to have a sleepless night, slight edema.Red and uncoated tongue, the thready pulse stringy and rapid pulse.Take 2 courses for the treatment of of medicament of Chinese medicine composition preparation of the present invention, have a dizzy spell, tinnitus disappears, and edema alleviates.Edema disappears after continuing to take 2 courses for the treatment of, and clear depending on thing, also can sleep peacefully night, urine frequency normalization.
Claims (2)
1. Chinese medicine composition for the treatment of the diabetic nephropathy edema, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: Radix Aconiti Lateralis Preparata 6-18 part, Poria 10-20 part, Radix Paeoniae Alba 6-18 part, Rhizoma Zingiberis 6-18 part, Exocarpium Benincasae 20-40 part, Semen Phaseoli 20-40 part, Semen Plantaginis 10-30 part, Radix Astragali 10-30 part, Rhizoma Dioscoreae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part.
2. a kind of Chinese medicine composition for the treatment of the diabetic nephropathy edema according to claim 1, it is characterized in that: its raw material of Chinese medicine by following weight portion proportioning forms: 12 parts of Radix Aconiti Lateralis Preparatas, 15 parts in Poria, 12 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Zingiberiss, 30 parts of Exocarpium Benincasaes, 30 parts of Semen Phaseolis, 20 parts of Semen Plantaginiss, 20 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes.
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| CN201210358556.9A CN102961696B (en) | 2012-09-25 | 2012-09-25 | Chinese medicinal composition for treating diabetic nephropathy edema |
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| CN201210358556.9A CN102961696B (en) | 2012-09-25 | 2012-09-25 | Chinese medicinal composition for treating diabetic nephropathy edema |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825918A (en) * | 2015-04-30 | 2015-08-12 | 刘德刚 | Traditional Chinese medicine for treating edema |
| CN108686188A (en) * | 2018-08-06 | 2018-10-23 | 首都医科大学附属北京中医医院 | A kind of Chinese medicine composition for treatment of kidney disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366617A (en) * | 2011-09-13 | 2012-03-07 | 成都绿迪科技有限公司 | Chinese patent medicine for treating idiopathic edema |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366617A (en) * | 2011-09-13 | 2012-03-07 | 成都绿迪科技有限公司 | Chinese patent medicine for treating idiopathic edema |
Non-Patent Citations (1)
| Title |
|---|
| 刘立芬: "真武汤加味治愈慢性肾炎(肾病型)高度浮肿2例", 《中医杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104825918A (en) * | 2015-04-30 | 2015-08-12 | 刘德刚 | Traditional Chinese medicine for treating edema |
| CN108686188A (en) * | 2018-08-06 | 2018-10-23 | 首都医科大学附属北京中医医院 | A kind of Chinese medicine composition for treatment of kidney disease |
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