CN104587257A - Traditional Chinese medicine composition for treating diabetic macular edema - Google Patents
Traditional Chinese medicine composition for treating diabetic macular edema Download PDFInfo
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- CN104587257A CN104587257A CN201510034935.6A CN201510034935A CN104587257A CN 104587257 A CN104587257 A CN 104587257A CN 201510034935 A CN201510034935 A CN 201510034935A CN 104587257 A CN104587257 A CN 104587257A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating diabetic macular edema. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 20-40 parts of Indian buead peel, 10-30 parts of agaric, 10-20 parts of oriental waterplantain rhizome, 9-15 parts of largehead atractylodes rhizome, 5-15 parts of cassia twig, 5-15 parts of herb of common knotgrass, 5-15 parts of herb of lilac pink, 20-40 parts of lalang grass rhizome, 10-30 parts of motherwort herb, 10-20 parts of plantain seed, 10-30 parts of root of lobed kudzuvine, 10-20 parts of hirsute shiny bugleweed herb, 10-30 parts of Japanese thistle herbor root, 10-30 parts of common cephalanoplos herb, 10-30 parts of Chinese waxgourd peel, 10-20 parts of raw milkvetch root, 3-9 parts of safflower, 9-15 parts of medicinal cyathula root and 10-30 parts of rice beans. The traditional Chinese medicine composition disclosed by the invention has the effects of soothing the liver, strengthening the spleen, activating blood, dissolving stasis, expelling phlegm, promoting diuresis, and clearing heat and removing toxicity, has significant curative effects and reliable functions on diabetic macular edema, is prepared from easily available medicinal raw materials, is simple and convenient to prepare, and cannot cause toxic or side effect.
Description
Technical field
The present invention relates to a kind of medicinal preparation not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of diabetic macular edema.
Background technology
Along with human living standard improves, the change of dietary structure, diabetes are increasingly general in the whole world.Diabetes can impact retina, i.e. diabetic retinopathy, and diabetic renal papillary necrosis mainly comprises proliferative retinopathy and diabetic macular edema.Diabetic macular edema refers to thicken or hard exudate deposition because the extracellular fluid within the scope of central fovea of macula disc diameter that diabetes cause gathers caused retina, causes central vision obviously to decline.At present, do not treat the specific medicament of diabetic macular edema, the laser that adopts adds the treatment of anti vegf agents intraocular injection more, and it exists the undesirable deficiency of curative effect.
The traditional Chinese medical science is thought, diabetic macular edema is mainly got old and weak due to patient, and deficiency of liver-QI declines or natural endowment deficiency, asthenia of both the spleen and kidney, stagnation of liver-QI hyperactivity of fire, phlegm-damp heat-dissipating, caused by function of five internal organs imbalance.
Be secondary to the multiple deficient property diseases such as diabetes due to primary disease more, take into account the pathological products such as phlegm-damp, for the pathogeny of diabetic macular edema, therefore treat when treating both the principal and secondary aspects of a disease based on tonify deficiency, with spleen invigorating, invigorate blood circulation, dampness removing is the rule for the treatment of, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Add anti vegf agents intraocular injection treatment diabetic macular edema there is the undesirable deficiency of curative effect to overcome laser in prior art, the invention provides a kind ofly to prepare conveniently, medicine source is wide, cost is low, curative effect reliable effect, the Chinese medicine composition for the treatment of diabetic macular edema that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of diabetic macular edema, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Sclerotii Poriae 20-40 part, Polyporus 10-30 part, Rhizoma Alismatis 10-20 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Ramulus Cinnamomi 5-15 part, Herba Polygoni Avicularis 5-15 part, Herba Dianthi 5-15 part, Rhizoma Imperatae 20-40 part, Herba Leonuri 10-30 part, Semen Plantaginis 10-20 part, Radix Puerariae 10-30 part, Herba Lycopi 10-20 part, Radix Cirsii Japonici 10-30 part, Herba Cirsii 10-30 part, Exocarpium Benincasae 10-30 part, Radix Astragali 10-20 part, Flos Carthami 3-9 part, Radix Cyathulae 9-15 part, Semen Ormosiae Hosiei 10-30 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of diabetic macular edema, is characterized in that: its raw material of Chinese medicine and weight are: Cortex Sclerotii Poriae 30 parts, Polyporus 20 parts, Rhizoma Alismatis 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Ramulus Cinnamomi 10 Fen ， Herba Polygoni Avicularis 10 parts, Herba Dianthi 10 parts, Rhizoma Imperatae 30 parts, Herba Leonuri 20 parts, Semen Plantaginis 15 parts, Radix Puerariae 20 parts, Herba Lycopi 15 parts, Radix Cirsii Japonici 20 parts, Herba Cirsii 20 parts, Exocarpium Benincasae 20 parts, Radix Astragali 15 parts, 6 parts, Flos Carthami, Radix Cyathulae 12 parts, Semen Ormosiae Hosiei 20 parts.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Cortex Sclerotii Poriae has effect of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming; Polyporus has effect of promoting diuresis to eliminate damp pathogen; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, expel the heat-evil treating stranguria function; The Rhizoma Atractylodis Macrocephalae has the antiabortive effect of invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Herba Polygoni Avicularis has effect of diuresis, heat clearing away, parasite killing; Herba Dianthi can fall heart-fire, sharp small intestinal, by bladder pathogenic heat, has inducing diuresis for treating stranguria syndrome, effect that removing blood stasis stimulates the menstrual flow; Rhizoma Imperatae has cooling blood for hemostasis, effect of heat-clearing and toxic substances removing; Herba Leonuri has effect of promoting blood flow to regulate menstruation, blood stasis dispelling diuretic, heat-clearing and toxic substances removing; Effect of Semen Plantaginis relieving stranguria by diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat-phlegm; Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Herba Lycopi has effect of blood circulation promoting and blood stasis dispelling, line water detumescence; Radix Cirsii Japonici has effect of cooling blood and relieving pain; Herba Cirsii has cooling blood for hemostasis, effect of clearing heat for detumescence; Exocarpium Benincasae has clearing away heat and promoting diuresis, effect of detumescence; Radix Astragali has effect that benefiting QI for strengthening the superficies, tonifying the lung spleen invigorating, arresting sweating are admittedly de-, wind dispelling fortune is malicious; Flos Carthami has effect of promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Radix Cyathulae has effect of eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome; Semen Ormosiae Hosiei possesses inducing diuresis to remove edema, effect of removing toxic substances and promoting pus discharge.Drug component in the present composition, through dialectical compatibility, complements each other using, has synergism, and effect of long memorial liver spleen, blood circulation promoting and blood stasis dispelling, the dampness removing that eliminates the phlegm, heat-clearing and toxic substances removing, reaches the object for the treatment of both the principal and secondary aspects of a disease to diabetic macular edema altogether.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, there is not toxic and side effects, total effective rate 82%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for diabetic macular edema, its raw material of Chinese medicine and weight proportion are: Cortex Sclerotii Poriae 30g, Polyporus 20g, Rhizoma Alismatis 15g, Rhizoma Atractylodis Macrocephalae 12g, Ramulus Cinnamomi 10g ， Herba Polygoni Avicularis 10g, Herba Dianthi 10g, Rhizoma Imperatae 30g, Herba Leonuri 20g, Semen Plantaginis 15g, Radix Puerariae 20g, Herba Lycopi 15g, Radix Cirsii Japonici 20g, Herba Cirsii 20g, Exocarpium Benincasae 20g, Radix Astragali 15g, Flos Carthami 6g, Radix Cyathulae 12g, Semen Ormosiae Hosiei 20g.
Embodiment 2
Treat a Chinese medicine composition for diabetic macular edema, its raw material of Chinese medicine and weight proportion are: Cortex Sclerotii Poriae 20g, Polyporus 30g, Rhizoma Alismatis 10g, Rhizoma Atractylodis Macrocephalae 15g, Ramulus Cinnamomi 5g ， Herba Polygoni Avicularis 15g, Herba Dianthi 5g, Rhizoma Imperatae 40g, Herba Leonuri 10g, Semen Plantaginis 20g, Radix Puerariae 10g, Herba Lycopi 20g, Radix Cirsii Japonici 10g, Herba Cirsii 10g, Exocarpium Benincasae 30g, Radix Astragali 10g, Flos Carthami 9g, Radix Cyathulae 9g, Semen Ormosiae Hosiei 30g.
Embodiment 3
Treat a Chinese medicine composition for diabetic macular edema, its raw material of Chinese medicine and weight proportion are: Cortex Sclerotii Poriae 40g, Polyporus 10g, Rhizoma Alismatis 20g, Rhizoma Atractylodis Macrocephalae 9g, Ramulus Cinnamomi 15g ， Herba Polygoni Avicularis 5g, Herba Dianthi 15g, Rhizoma Imperatae 20g, Herba Leonuri 30g, Semen Plantaginis 10g, Radix Puerariae 30g, Herba Lycopi 10g, Radix Cirsii Japonici 30g, Herba Cirsii 30g, Exocarpium Benincasae 10g, Radix Astragali 20g, Flos Carthami 3g, Radix Cyathulae 15g, Semen Ormosiae Hosiei 10g.
Embodiment 4
Treat a Chinese medicine composition for diabetic macular edema, its raw material of Chinese medicine and weight proportion are: Cortex Sclerotii Poriae 25g, Polyporus 25g, Rhizoma Alismatis 12g, Rhizoma Atractylodis Macrocephalae 13g, Ramulus Cinnamomi 8g ， Herba Polygoni Avicularis 13g, Herba Dianthi 8g, Rhizoma Imperatae 35g, Herba Leonuri 15g, Semen Plantaginis 18g, Radix Puerariae 15g, Herba Lycopi 18g, Radix Cirsii Japonici 15g, Herba Cirsii 15g, Exocarpium Benincasae 25g, Radix Astragali 12g, Flos Carthami 8g, Radix Cyathulae 10g, Semen Ormosiae Hosiei 25g.
Embodiment 5
Treat a Chinese medicine composition for diabetic macular edema, its raw material of Chinese medicine and weight proportion are: Cortex Sclerotii Poriae 35g, Polyporus 15g, Rhizoma Alismatis 18g, Rhizoma Atractylodis Macrocephalae 10g, Ramulus Cinnamomi 13g ， Herba Polygoni Avicularis 8g, Herba Dianthi 13g, Rhizoma Imperatae 25g, Herba Leonuri 25g, Semen Plantaginis 12g, Radix Puerariae 25g, Herba Lycopi 12g, Radix Cirsii Japonici 25g, Herba Cirsii 25g, Exocarpium Benincasae 15g, Radix Astragali 18g, Flos Carthami 4g, Radix Cyathulae 13g, Semen Ormosiae Hosiei 15g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Twice decoction is removed slag extracting juice, merges.
The present invention, with a kind of Chinese medicine composition for the treatment of diabetic macular edema given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 100 eyes, wherein man 40 example, female 60 example, age 35-80 year.The shortest person of the course of disease 6 months, most elder reaches 3 years.
Two, inspection method: by examination of ocular fundus, optical coherence tomography and fluorescent contrast examination.Wherein examination of ocular fundus mainly uses the special optical fundus of optical fundus camera lens to patient to check by ophthalmology specialist, comprise check macular area and retina whether have hemorrhage, come off or diabetic renal papillary necrosis, macular edema etc.Optical coherence tomography mainly measures the thickness of macular edema with what.Fluorescent contrast examination confirms whether retina exists the situation of anoxia.
Three, validation criteria: for possessing with the next item down or more than one person:
1, retina is had to thicken within the scope of central fovea of macula 500 μm;
2, there is hard exudate within the scope of central fovea of macula 500 μm and thicken with contiguous retina;
3, a region or multiple regions retina thicken, and its size is 1 disc diameter or larger, and its any position is positioned at apart from central fovea of macula 1 disc diameter.
Four, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice is about 300ml, and point early, late twice half an hour ante cibum warmly take.Five days is a course for the treatment of, and period in a medicine is avoided eating anything raw or cold, pungent thing.
Five, criterion of therapeutical effect:
1, effective: macular edema symptom alleviates, and vision is obviously improved;
2, effective: macular edema symptom is alleviated to some extent, and vision improves;
3, invalid: macular edema severity of symptoms, visual loss.
Six, therapeutic effect: in this clinical observation case, takes medicine 5-20 the course for the treatment of, effective 40 examples, effective 42 examples, invalid 18 examples.There is not toxic and side effects in treatments period.
Seven, model case:
Case 1: Huang, man, 58 years old, diabetic history 10 years, beat insulin always, in recent years start to occur blurred vision, make a definite diagnosis diabetic macular edema, after laser therapy is invalid, after 5 courses for the treatment of of medicament of taking prepared by Chinese medicine composition of the present invention, macular edema is alleviated to some extent, and vision improves; After continuing to take 4 courses for the treatment of, vision brings up to 0.6 by original 0.2, and vision is obviously improved.
Case 2: field, female, 52 years old, diabetic history 8 years, retinal hemorrhage and macular edema, vision is very poor, and did laser surgery and intraocular injection Drug therapy, macular edema is alleviated to some extent, take 10 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, macular edema symptom alleviates, and vision is obviously improved, and obtains better therapeutic effect.
Claims (2)
1. treat the Chinese medicine composition of diabetic macular edema for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Sclerotii Poriae 20-40 part, Polyporus 10-30 part, Rhizoma Alismatis 10-20 part, Rhizoma Atractylodis Macrocephalae 9-15 part, Ramulus Cinnamomi 5-15 Fen ， Herba Polygoni Avicularis 5-15 part, Herba Dianthi 5-15 part, Rhizoma Imperatae 20-40 part, Herba Leonuri 10-30 part, Semen Plantaginis 10-20 part, Radix Puerariae 10-30 part, Herba Lycopi 10-20 part, Radix Cirsii Japonici 10-30 part, Herba Cirsii 10-30 part, Exocarpium Benincasae 10-30 part, Radix Astragali 10-20 part, Flos Carthami 3-9 part, Radix Cyathulae 9-15 part, Semen Ormosiae Hosiei 10-30 part.
2. a kind of Chinese medicine composition for the treatment of diabetic macular edema according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: Cortex Sclerotii Poriae 30 parts, Polyporus 20 parts, Rhizoma Alismatis 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Ramulus Cinnamomi 10 Fen ， Herba Polygoni Avicularis 10 parts, Herba Dianthi 10 parts, Rhizoma Imperatae 30 parts, Herba Leonuri 20 parts, Semen Plantaginis 15 parts, Radix Puerariae 20 parts, Herba Lycopi 15 parts, Radix Cirsii Japonici 20 parts, Herba Cirsii 20 parts, Exocarpium Benincasae 20 parts, Radix Astragali 15 parts, 6 parts, Flos Carthami, Radix Cyathulae 12 parts, Semen Ormosiae Hosiei 20 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873672A (en) * | 2015-06-19 | 2015-09-02 | 李进 | Traditional Chinese medicine for treating diabetes mild macular oedema |
| CN105748760A (en) * | 2016-03-15 | 2016-07-13 | 江琴 | Medicine composition for treating macular edema of old people |
| KR20180041232A (en) * | 2015-09-10 | 2018-04-23 | 밍 진 | A medicinal composition for treating diabetic retinopathy |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188637A (en) * | 2011-05-06 | 2011-09-21 | 吴幼锐 | Traditional Chinese drug composition for treating macular degeneration, and preparation method thereof |
| CN102846876A (en) * | 2011-06-30 | 2013-01-02 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for an integrated new formulation of Wuqin wine |
| CN103705899A (en) * | 2014-01-07 | 2014-04-09 | 成都中医药大学附属医院 | Pharmaceutical composition for treating diabetic retinopathy and preparation method and use thereof |
-
2015
- 2015-01-25 CN CN201510034935.6A patent/CN104587257A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188637A (en) * | 2011-05-06 | 2011-09-21 | 吴幼锐 | Traditional Chinese drug composition for treating macular degeneration, and preparation method thereof |
| CN102846876A (en) * | 2011-06-30 | 2013-01-02 | 苏州知微堂生物科技有限公司 | Preparation technology and production method for an integrated new formulation of Wuqin wine |
| CN103705899A (en) * | 2014-01-07 | 2014-04-09 | 成都中医药大学附属医院 | Pharmaceutical composition for treating diabetic retinopathy and preparation method and use thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘婷婷等: "复方血栓通胶囊联合五苓散加减在糖尿病视网膜病变围光凝期的应用", 《中国中医眼科杂志》 * |
| 张林平: "中药五苓散加味治疗糖尿病黄斑水肿的临床分析", 《糖尿病新世界》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873672A (en) * | 2015-06-19 | 2015-09-02 | 李进 | Traditional Chinese medicine for treating diabetes mild macular oedema |
| KR20180041232A (en) * | 2015-09-10 | 2018-04-23 | 밍 진 | A medicinal composition for treating diabetic retinopathy |
| KR102099520B1 (en) | 2015-09-10 | 2020-04-09 | 밍 진 | Chinese medicine composition to treat diabetic retinopathy |
| CN105748760A (en) * | 2016-03-15 | 2016-07-13 | 江琴 | Medicine composition for treating macular edema of old people |
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