A kind of medicine for the treatment of cold injury
Technical field
The present invention relates to technical field of traditional Chinese medicine pharmacy, particularly relate to a kind of medicine for the treatment of cold injury.
Background technology
Cold injury refers to endure cold and the formed damage when reducing of local blood when soft tissue, cold injury just may take place when skin temperature drops to-2 ℃, temperature cold injury incidence rate in the time of-25 ℃~-30 ℃ is the highest, be divided into according to degree of injury: cold injury once: show as erythema, edema, skin paralysis and of short duration pain, skin lesion can recover fully, only with slight desquamation; Two degree cold injury: be characteristics with tangible hyperemia, edema and vesicle, bleb liquid is limpid; Skin lesion can heal, but can leave long-term sensory nerve pathological changes, often with tangible cold allergy; Three degree cold injury: comprise corium holostrome damage, form or wax shape, drying, mummy sample skin with blood blister; The tissue forfeiture, prognosis mala; Four degree cold injury: the thorough forfeiture of skin holostrome comprises the destruction of skin, muscle, tendon and skeleton can causing amputation.
At present, the medicine for the treatment of cold injury once, two degree cold injury is more, but exist treatment time long, effect is undesirable, side effect is big, the high deficiency of drug price.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of medicine for the treatment of cold injury, the present invention is applicable to and once treats cold injury, two degree cold injury, and the present invention has instant effect, evident in efficacy, side effect is little, cost is low, preparation is easy advantage.
A kind of medicine for the treatment of cold injury is characterized in that: made by following bulk drugs: Radix Astragali 13-17 part, Ramulus Cinnamomi 10-14 part, Cortex Cinnamomi 10-14 part, Olibanum 10-14 part, Radix Angelicae Sinensis 8-12 part, Radix Saposhnikoviae 8-12 part, Fructus Piperis 8-12 part, Cortex Phellodendri 8-12 part, Radix Glycyrrhizae 8-11 part, Folium Artemisiae Argyi 8-11 part, Rhizoma Zingiberis Recens 8-11 part, Herba Schizonepetae 6-8 part, Radix Paeoniae Alba 6-8 part, Radix Paeoniae Rubra 6-8 part, Herba Asari 6-8 part, Flos Carthami 4-6 part, Camphora 4-6 part, 75% ethanol 500-700 part.
The medicine of described treatment cold injury is characterized in that: made by following bulk drugs: 15 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 12 parts of Cortex Cinnamomis, 12 parts of Olibanums, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Saposhnikoviaes, 10 parts in Fructus Piperis, 10 parts of Cortex Phellodendris, 9 parts in Radix Glycyrrhizae, 9 parts of Folium Artemisiae Argyis, 9 parts in Rhizoma Zingiberis Recens, 7 parts of Herba Schizonepetae, 7 parts of the Radix Paeoniae Albas, 7 parts of Radix Paeoniae Rubra, 7 parts of Herba Asaris, 5 parts on Flos Carthami, 5 parts of Camphoras, 600 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury may further comprise the steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali that will take by weighing, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to the 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soaked 10 days, namely get medicinal liquid after the filtration.
Usage and consumption: be applied to cold injury place, every day 3-4 time with the cotton swab dip in liquid medicine.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
The Radix Astragali: meridian distribution of property and flavor: sweet, tepor; Effect: polishing consolidating superficial resistance, holder skin ulcer granulation promoting.
Ramulus Cinnamomi: meridian distribution of property and flavor: hot, sweet, temperature, GUIXIN, lung, urinary bladder channel; The diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Cortex Cinnamomi: meridian distribution of property and flavor: hot, sweet, big heat, return kidney, spleen, the heart, Liver Channel; Effect: mend that fire is supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
Olibanum: meridian distribution of property and flavor: suffering, hardship, tepor; GUIXIN, liver, spleen channel; Effect: blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation.
Radix Angelicae Sinensis: meridian distribution of property and flavor: sweet, hot, warm; Return liver, the heart, spleen channel; Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.
Radix Saposhnikoviae: meridian distribution of property and flavor: hot, sweet, tepor, return bladder, lung, spleen, liver; Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic.
Fructus Piperis: meridian distribution of property and flavor: suffering, heat is returned stomach, large intestine channel; Effect: warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.
Cortex Phellodendri: meridian distribution of property and flavor: hardship, cold; Return kidney, urinary bladder channel; Effect: heat clearing and damp drying, pathogenic fire purging is except steaming, and skin ulcer is treated in detoxifcation.
Radix Glycyrrhizae: meridian distribution of property and flavor: sweet, flat, GUIXIN, lung, spleen, stomach warp; Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Folium Artemisiae Argyi: meridian distribution of property and flavor: hot, bitter, temperature, slightly poisonous, return the liver,spleen,kidney warp; Effect: dispersing cold for relieving pain, warming the meridian for stopping bleeding.
Rhizoma Zingiberis Recens: meridian distribution of property and flavor: suffering, tepor is returned lung, spleen, stomach warp; Effect: the cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.
Herba Schizonepetae: meridian distribution of property and flavor: hot, tepor, return lung, Liver Channel; Effect: the diffusing wind that induces sweat, rash.
The Radix Paeoniae Alba: meridian distribution of property and flavor: be slightly cold, bitter, sour, return liver, spleen channel; Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Radix Paeoniae Rubra: meridian distribution of property and flavor: be slightly cold, hardship, return Liver Channel; Effect: clearing away heat and cooling blood, eliminating stasis to stop pain.
Herba Asari: meridian distribution of property and flavor: hot, warm, GUIXIN, lung, kidney channel; Effect: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.
Flos Carthami: meridian distribution of property and flavor: hot, warm, GUIXIN, Liver Channel; Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
Camphora: meridian distribution of property and flavor: suffering, heat; GUIXIN, spleen channel; Effect: sensible, parasite killing, pain relieving is warded off dirty.
The present invention has warming the meridian and promoting blood circulation, the cold expelling stasis of blood, removing damp to relieve itching, anti-inflammation alive, holds back the effect of creation flesh, thereby reach the purpose for the treatment of cold injury with above-mentioned each crude drug and the made medicinal liquid of proportioning thereof.
The beneficial effect that the present invention compared with prior art has is: the present invention have instant effect, evident in efficacy, side effect is little, cost is low, the easy advantage of preparation; Through clinical verification, the effective percentage of cold injury, two degree cold injury is 100% for once treating in the present invention.
The specific embodiment
Embodiment 1:
A kind of medicine for the treatment of cold injury is characterized in that: made by following bulk drugs: 15 parts of the Radixs Astragali, 12 parts of Ramulus Cinnamomi, 12 parts of Cortex Cinnamomis, 12 parts of Olibanums, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Saposhnikoviaes, 10 parts in Fructus Piperis, 10 parts of Cortex Phellodendris, 9 parts in Radix Glycyrrhizae, 9 parts of Folium Artemisiae Argyis, 9 parts in Rhizoma Zingiberis Recens, 7 parts of Herba Schizonepetae, 7 parts of the Radix Paeoniae Albas, 7 parts of Radix Paeoniae Rubra, 7 parts of Herba Asaris, 5 parts on Flos Carthami, 5 parts of Camphoras, 600 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury may further comprise the steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali that will take by weighing, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to the 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soaked 10 days, namely get medicinal liquid after the filtration.
Embodiment 2:
A kind of medicine for the treatment of cold injury is characterized in that: made by following bulk drugs: 13 parts of the Radixs Astragali, 10 parts of Ramulus Cinnamomi, 10 parts of Cortex Cinnamomis, 10 parts of Olibanums, 8 parts of Radix Angelicae Sinensis, 8 parts of Radix Saposhnikoviaes, 8 parts in Fructus Piperis, 8 parts of Cortex Phellodendris, 8 parts in Radix Glycyrrhizae, 8 parts of Folium Artemisiae Argyis, 8 parts in Rhizoma Zingiberis Recens, 6 parts of Herba Schizonepetae, 6 parts of the Radix Paeoniae Albas, 6 parts of Radix Paeoniae Rubra, 6 parts of Herba Asaris, 4 parts on Flos Carthami, 4 parts of Camphoras, 500 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury may further comprise the steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali that will take by weighing, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to the 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soaked 10 days, namely get medicinal liquid after the filtration.
Embodiment 3:
A kind of medicine for the treatment of cold injury is characterized in that: made by following bulk drugs: 17 parts of the Radixs Astragali, 14 parts of Ramulus Cinnamomi, 14 parts of Cortex Cinnamomis, 14 parts of Olibanums, 12 parts of Radix Angelicae Sinensis, 12 parts of Radix Saposhnikoviaes, 12 parts in Fructus Piperis, 12 parts of Cortex Phellodendris, 11 parts in Radix Glycyrrhizae, 11 parts of Folium Artemisiae Argyis, 11 parts in Rhizoma Zingiberis Recens, 8 parts of Herba Schizonepetae, 8 parts of the Radix Paeoniae Albas, 8 parts of Radix Paeoniae Rubra, 8 parts of Herba Asaris, 6 parts on Flos Carthami, 6 parts of Camphoras, 700 parts of 75% ethanol.
The preparation method of the medicine of described treatment cold injury may further comprise the steps:
(1) according to described parts by weight weighting raw materials: the Radix Astragali, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, Camphora, 75% ethanol are standby;
(2) Radix Astragali that will take by weighing, Ramulus Cinnamomi, Cortex Cinnamomi, Olibanum, Radix Angelicae Sinensis, Radix Saposhnikoviae, Fructus Piperis, Cortex Phellodendri, Radix Glycyrrhizae, Folium Artemisiae Argyi, Rhizoma Zingiberis Recens, Herba Schizonepetae, the Radix Paeoniae Alba, Radix Paeoniae Rubra, Herba Asari, Flos Carthami, camphor powder are broken to the 100-120 order, sterilization, mixing;
(3) step (2) gained mixture is put into 75% ethanol, soaked 10 days, namely get medicinal liquid after the filtration.
Experimental example:
One, clinical data: adopt the present invention to treat once cold injury, two degree cold injury patients, 66 examples, male 27 examples wherein, women 39 examples, the oldest 65 years old, minimum 7 years old of age.
Two, clinical symptoms: cold injury once: erythema, edema, skin paralysis and pain, only with slight desquamation; Two degree cold injury: hyperemia, edema and vesicle are arranged, and bleb liquid is limpid, and pain is often with tangible cold allergy.
Three, Therapeutic Method: be applied to cold injury place, every day 3-4 time with the cotton swab dip in liquid medicine.
Four, therapeutic evaluation standard:
Cure: transference cure, lump dissipates, wound healing;
Take a turn for the better: symptom is obviously improved, and wound surface is healing fully not;
Do not heal: symptom is not improved.
Five, model case:
1, Chen, the woman, 42 years old, annual winter, cold injury all took place in hand, face, and symptom shows as the rounded aubergine edema of skin of face erythema, and hand swelling etc. are two degree cold injury; The medicine that uses treatment cold injury of the present invention after 7 days symptom obviously improve recovery from illness in 15 days; 1 year winter, advise and continue to use this medicine, cold injury does not take place again, follow up a case by regular visits to not recurrence in 3 years.
2, season so-and-so, the man, 14 years old, cold injury all took place annual winter in ear, symptom shows as erythema, edema, skin paralysis and pain etc.; Be cold injury once; The medicine that uses treatment cold injury of the present invention after 5 days symptom obviously improve, not recurrence in 4 years is followed up a case by regular visits in recovery from illness in 10 days.
Six, therapeutic outcome:
Adopt the present invention to treat once cold injury, two degree cold injury patients, 66 examples, through 10-20 days treatment, wherein cure 61 examples, 5 examples that take a turn for the better, cure rate is 92%, effective percentage is 100%; The result shows, the present invention has instant effect, evident in efficacy, advantage that side effect is little.