CN107802788A - A kind of capsule medicine and preparation method for being used to treat gout - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of capsule medicine for being used to treat gout be provided according to the understanding mechanism of Chinese traditional treatment gout, each component and its mass parts ratio of the medicine are as follows：100~300g of notopterygium root, 60~160g of Lygodium japonicum, 150~650g of desmodium, 50~160g of the red sage root, 30~120g of the bark of official magnolia, 100~350g of black soya bean, 90~350g of caulis lonicerae, 30~120g of curcuma zedoary, 30~120g of cortex magnoliae officinalis, 150~550g of coix seed, 30~120g of the membrane of a chicken's gizzard, 30~160g of dried orange peel, 30~120g of bulbus fritillariae cirrhosae, 30~70g of fructus amomi, 30~70g of myrrh, 60~160g of umbellate pore furgus；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of capsule medicine and preparation method for being used to treat gout

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of capsule medicine for being used to treat gout, particularly supply The capsule medicine and the field of preparation method that patient with gout uses.

Background technology

Shown according to relevant document：Gout is by monosodium urate salt（MSU）Crystal correlation arthropathy caused by deposition, it is and fast Purine metabolic disorder and（Or）Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and slow Property tophus disease, mainly include acute attack arthritis, tophus formation, tophaceous chornic arthritis, lithate kidney Sick and uric acid lithangiuria, severe one may occur in which joint deformity and renal insufficiency.Gout often with Central obesity, hyperlipidemia, Hypertension, diabetes B and cardiovascular disease etc. show.

So, a kind of Chinese medicine composition that can effectively treat gout how is just found, is that those skilled in the art urgently will Solve the problems, such as.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment gout, people gradually appreciate Chinese traditional treatment pain The advantages of wind, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment gout Present situation, the purpose of the present invention is to be to provide a kind of capsule medicine for being used to treat gout, extensive early to solve patient with gout The problem of rehabilitation health.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be controlled Treat above-mentioned gout.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating gout Capsule medicine and preparation method, it is characterised in that each component and mass parts of the medicine are than as follows：

It is 100~300g of notopterygium root, 60~160g of Lygodium japonicum, 150~650g of desmodium, 50~160g of the red sage root, 30~120g of the bark of official magnolia, black 100~350g of beans, 90~350g of caulis lonicerae, 30~120g of curcuma zedoary, 30~120g of cortex magnoliae officinalis, 150~550g of coix seed, the membrane of a chicken's gizzard 30 ~120g, 30~160g of dried orange peel, 30~120g of bulbus fritillariae cirrhosae, 30~70g of fructus amomi, 30~70g of myrrh, 60~160g of umbellate pore furgus, auxiliary material： Talcum powder and appropriate starch.

A kind of capsule medicine and preparation method for being used to treat gout, it is characterised in that each component of the medicine And mass parts are than as follows：

It is 115~260g of notopterygium root, 70~140g of Lygodium japonicum, 180~560g of desmodium, 58~140g of the red sage root, 38~105g of the bark of official magnolia, black 115~310g of beans, 100~310g of caulis lonicerae, 38~105g of curcuma zedoary, 38~105g of cortex magnoliae officinalis, 180~480g of coix seed, the membrane of a chicken's gizzard 38~105g, 38~140g of dried orange peel, 38~105g of bulbus fritillariae cirrhosae, 38~60g of fructus amomi, 38~60g of myrrh, umbellate pore furgus 70~140g, it is auxiliary Material：Talcum powder and appropriate starch.

A kind of capsule medicine and preparation method for being used to treat gout, it is characterised in that each component of the medicine And mass parts are than as follows：

Notopterygium root 230g, Lygodium japonicum 120g, desmodium 500g, red sage root 120g, bark of official magnolia 95g, black soya bean 280g, caulis lonicerae 280g, curcuma zedoary 95g, cortex magnoliae officinalis 95g, coix seed 420g, the membrane of a chicken's gizzard 95g, dried orange peel 120g, bulbus fritillariae cirrhosae 95g, fructus amomi 52g, myrrh 52g, umbellate pore furgus 120g, Auxiliary material：Talcum powder and appropriate starch.

A kind of capsule medicine and preparation method for being used to treat gout, it is characterised in that methods described includes following step Suddenly it is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, the raw material Chinese medicine wrapped is put into after soaking 35min in cold boiling water, then soaked medicine is put into marmite and decocted Three times：1. amount of water is 9~10 times of medicinal material total amount, high heat decoction is first carried out, when 15min is arrived in decoction, turns slow fire and boils 115 Min, leaching decoction；2. amount of water is 8~9 times of dry dregs of a decoction total amount, high heat decoction is first carried out, when 10min is arrived in decoction, is turned Slow fire boils 105 min, leaching decoction；3. amount of water is 7~8 times of dry dregs of a decoction total amount, high heat decoction is first carried out, waits to decoct During to 8min, turn slow fire and boil 90 min, leaching decoction；4. merging decoction three times, and it is concentrated under reduced pressure into every milliliter contained 3g Standard after, that is, obtain drug extract.

C, by the extract dry prepared in above-mentioned B, sterilization, and it is standby according to mass parts ratio to be ground into superfine end；

D, the method for preparing Chinese medicine capsules according to traditional common process and auxiliary material, by superfine myrrh thing mistake ground in C After sieve, then above-mentioned starch and talcum powder are put into medicine device in the lump and are well mixed, be then prepared into capsule（After its capsule is sealed Total length be 23.3mm, medicinal powder capacity 0.4~0.5g/ grains）, then polish, sterilize, sealed packaging produces.

It is a kind of to be used to treat the capsule medicine and preparation method of gout, it is characterised in that the instructions of taking is：Will system The capsule medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, dosage 3g（6）/ time, warm water delivery service.10 It is a course for the treatment of, treats 3~7 courses for the treatment of, and symptom disappears, and checks：Blood uric acid recovers normal.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Notopterygium root, nature and flavor：Arduous, temperature, has the effect of dissipating exterior cold, wind-damp dispelling, sharp joint, for treating cold, headache nothing Sweat, wind-cold-dampness arthralgia, item strengthening tendons urgency, joint ache, geomantic omen edema, skin sore；

Lygodium japonicum, nature and flavor：It is sweet, salty, cold in nature, there is the effect of eliminating dampness and heat, treating stranguria analgesic, for treating heat gonorrhea, urolithiasis, blood Leaching, cream leaching, Urethra astringent pain；

Desmodium, nature and flavor：Sweet, salty, cold nature, there is the effect of removing dampness through diuresis and removing jaundice, inducing diuresis for treating strangurtia, removing toxicity for detumescence, for treating Jaundice with damp-heat pathogen, courage are swollen hypochondriac pain, urolithiasis, heat gonorrhea, difficulty and pain in micturition, carbuncle swells furunculosis, snake bite and insect sting；

The red sage root, nature and flavor：Bitter, cold nature, there is the effect of promoting blood circulation, menstruction regulating and pain relieving, nourishing blood and tranquilization, cool blood to disappear carbuncle, be used for Treat menoxenia, dysmenorrhoea, Amenorrhea, postpartum stasis of blood, trusted subordinate's pain, lumps in the chest and abdomen, the swelling and pain of hot numbness, traumatic injury, Heat enters ying blood, dysphoria, vexed insomnia, ulcerative carbuncle pyogenic infections；

The bark of official magnolia, nature and flavor：It is bitter, pungent, warm, there is the effect of eliminating dampness dissolving phlegm, lower gas removes full, it is swollen for treating damp retention in middle-jiao, gastral cavity abdomen Full, stagnation of QI due to dyspepsia, abdominal distention constipation, sputum cough；In addition, seven feelings pent-ups, mental disorder mutual resistance, hindered in pharynx if any thing, pharynx not under, tell The globus hysteriocus not gone out card, also can use this product eliminating dampness dissolving phlegm, the effect during lower gas is wide；

Black soya bean, nature and flavor：It is sweet, flat, there is the effect of benefiting shrewd head, nourishing the blood to expel wind, Li Shui, removing toxic substances, for treating deficiency of Yin polydipsia, head Dizzy blurred vision, body void hidrosis, lumbago due to the kidney deficiency, oedema oliguria, numbness pain contraction, numb in every limb, medicine food poisoning；

Caulis lonicerae, nature and flavor：It is sweet, cold, there is the effect of clearing heat and detoxicating, dispelling wind dredging collateral, for treat warm disease heating, toxic-heat and blood stasis, Carbuncle swells sore, beriberoid pyretic arthralgia, redness and swelling of joints heat pain；

Curcuma zedoary, nature and flavor：Toil, temperature, there is the effect of blood-breaking, Xiao Ji Zhi Tong, for treat pained vim and vigour, eating accumulation, Abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury, be additionally operable to abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, Accumulation, abdominal mass lump, women's blood stasis, traumatic injury are had a pain eating accumulation, and it is antitumor that modern pharmacology shows that oriental wormwood has Effect：Its aromatic turmeric oil preparation is in vitro to Mouse Ehrlich Carcinoma Cells, the L615 leukaemia of 615 mouse inbred lines and ascitic type The growth of a variety of knurl strains such as liver cancer cells has obvious suppression and destruction.Clinic makees intratumoral injection uterine neck with oil of zedoary turmeric Cancer, after treatment visible tumor tissue necrosis come off, local lymphocytes infiltration, some cases lump disappear, uterine neck is smooth, prompt cowherb Art plays the role of directly to kill oncocyte；

Cortex magnoliae officinalis, nature and flavor：It is bitter, pungent, warm-natured, there is the effect of gas consumption product, eliminating dampness except full, relieving asthma, for treating dyspepsia gas Stagnant, abdominal distention constipation, damp retention in middle-jiao, abdominal swelling and diarrhea, phlegm stops up the circulation of vital energy in the wrong direction, chest full of cough；

Coix seed, nature and flavor：It is sweet, light, be slightly cold, have dampness removing invigorating the spleen, relaxing muscles and tendons eliminating impediment, clearing away heat and eliminating pus the effect of, for treat oedema, Under tinea pedis, dribbling urination, damp-warm diseases, diarrhea band, the disease such as arthralgia pain due to rheumatism, muscle arteries and veins contraction, lung carbuncle, acute appendicitis, flat wart；

The membrane of a chicken's gizzard, nature and flavor：It is sweet, flat, have stomach strengthening and digestion promoting, arresting seminal emission, treating stranguria fossil the effect of, for treat dyspepsia, Vomiting dysentery, infantile malnutrition, the enuresis, seminal emission, the puckery pain of urolithiasis, courage is swollen hypochondriac pain；

Dried orange peel, nature and flavor：It is acrid flavour, hardship, warm-natured, have qi-regulating and in, it is eliminating dampness and eliminating phlegm, the effect of sharp water defaecation, for treating taste Discord, abdominal distention, do not feel like eating, vomiting hiccup, phlegm-damp obstructing lung, coughing with a lot of sputum, the full vexed, vertigo of chest diaphragm, oedema, urine The diseases such as unfavorable, constipation, acute mastitis mange, middle ichthyophagy crab poison, wine poison；

Bulbus fritillariae cirrhosae, nature and flavor：It is cool in nature, Gan Ping, there is the effect of resolving sputum and relieving asthma that moistens the lung and relieve the cough, clearing heat and eliminating phlegm, it is dry for treating lung heat The diseases such as cough, the few phlegm of dry cough, deficiency of Yin overstrain cough, blood-stained sputum, scrofula, acute mastitis, lung carbuncle；

Fructus amomi, nature and flavor：It is acrid flavour, warm-natured, there is the effect of dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy antiabortive, for treat it is wet it is turbid in Resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, pernicious vomiting, fetal irritability；

Myrrh, nature and flavor：It is acrid flavour, hardship, mild-natured, there is the effect of scattered stasis pain, detumescence and promoting granulation, for treating chest impediment and cardialgia, gastral cavilty Pain, dysmenorrhoea Amenorrhea, postpartum stasis, Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, carbuncle swells sore；

Umbellate pore furgus, nature and flavor：Gan Ping, there is the effect of clearing damp and promoting diuresis, for treating ephritis, difficult urination, stranguria with turbid discharge renal shutdown, oedema diarrhea Deng disease.

Medicine of the present invention is the principle based on Chinese traditional treatment gout, is recognized from the pathomechanism according to gout and pharmacological action For：With regard to gout, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned gout, the medicine prepared using the formula Good drug efficacy, it is quick, it is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the specific implementation of the present invention Mode is described in further detail：

Embodiment 1：

A kind of capsule medicine for being used to treat gout, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Notopterygium root 230g, Lygodium japonicum 120g, desmodium 500g, red sage root 120g, bark of official magnolia 95g, black soya bean 280g, caulis lonicerae 280g, curcuma zedoary 95g, cortex magnoliae officinalis 95g, coix seed 420g, the membrane of a chicken's gizzard 95g, dried orange peel 120g, bulbus fritillariae cirrhosae 95g, fructus amomi 52g, myrrh 52g, umbellate pore furgus 120g, Auxiliary material：Talcum powder and appropriate starch.

Embodiment 2：

A kind of capsule medicine for being used to treat gout, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Notopterygium root 260g, Lygodium japonicum 140g, desmodium 560g, red sage root 140g, bark of official magnolia 105g, black soya bean 310g, caulis lonicerae 310g, curcuma zedoary 105g, cortex magnoliae officinalis 105g, coix seed 480g, the membrane of a chicken's gizzard 105g, dried orange peel 140g, bulbus fritillariae cirrhosae 105g, fructus amomi 60g, myrrh 60g, umbellate pore furgus 140g, auxiliary material：Talcum powder and appropriate starch.

Embodiment 3：

A kind of capsule medicine for being used to treat gout, it is characterised in that each component and mass parts ratio of the medicine are as follows It is shown：

Notopterygium root 300g, Lygodium japonicum 160g, desmodium 650g, red sage root 160g, bark of official magnolia 120g, black soya bean 350g, caulis lonicerae 350g, curcuma zedoary 120g, cortex magnoliae officinalis 120g, coix seed 550g, the membrane of a chicken's gizzard 120g, dried orange peel 160g, bulbus fritillariae cirrhosae 120g, fructus amomi 70g, myrrh 70g, umbellate pore furgus 160g, auxiliary material：Talcum powder and appropriate starch.

Model case：

Through clinical conditions patient with gout totally 1378, the age is 817 of more than 56 years old, and only 561 are less than 56 years old. Blood uric acid recovers normally have 920, effective 320, invalid 138 in 1378 patients.Total effective rate is up to 90%.

Claims (3)

1. A kind of 1. capsule medicine for being used to treat gout, it is characterised in that each component and its mass parts ratio of the medicine It is as follows：

   It is 100~300g of notopterygium root, 60~160g of Lygodium japonicum, 150~650g of desmodium, 50~160g of the red sage root, 30~120g of the bark of official magnolia, black 100~350g of beans, 90~350g of caulis lonicerae, 30~120g of curcuma zedoary, 30~120g of cortex magnoliae officinalis, 150~550g of coix seed, the membrane of a chicken's gizzard 30 ~120g, 30~160g of dried orange peel, 30~120g of bulbus fritillariae cirrhosae, 30~70g of fructus amomi, 30~70g of myrrh, 60~160g of umbellate pore furgus, auxiliary material： Talcum powder and appropriate starch.
2. 2. the capsule medicine according to claim 1 for being used to treat gout, it is characterised in that each group of the medicine Divide and its mass parts are than as follows：

   It is 115~260g of notopterygium root, 70~140g of Lygodium japonicum, 180~560g of desmodium, 58~140g of the red sage root, 38~105g of the bark of official magnolia, black 115~310g of beans, 100~310g of caulis lonicerae, 38~105g of curcuma zedoary, 38~105g of cortex magnoliae officinalis, 180~480g of coix seed, the membrane of a chicken's gizzard 38~105g, 38~140g of dried orange peel, 38~105g of bulbus fritillariae cirrhosae, 38~60g of fructus amomi, 38~60g of myrrh, umbellate pore furgus 70~140g, it is auxiliary Material：Talcum powder and appropriate starch.
3. 3. being used for according to claim 1 to 2 treats the capsule medicine of gout, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

   Notopterygium root 230g, Lygodium japonicum 120g, desmodium 500g, red sage root 120g, bark of official magnolia 95g, black soya bean 280g, caulis lonicerae 280g, curcuma zedoary 95g, cortex magnoliae officinalis 95g, coix seed 420g, the membrane of a chicken's gizzard 95g, dried orange peel 120g, bulbus fritillariae cirrhosae 95g, fructus amomi 52g, myrrh 52g, umbellate pore furgus 120g, Auxiliary material：Talcum powder and appropriate starch.