CN107951740A - A kind of anti-aging lotion and preparation method thereof - Google Patents
A kind of anti-aging lotion and preparation method thereof Download PDFInfo
- Publication number
- CN107951740A CN107951740A CN201810040840.9A CN201810040840A CN107951740A CN 107951740 A CN107951740 A CN 107951740A CN 201810040840 A CN201810040840 A CN 201810040840A CN 107951740 A CN107951740 A CN 107951740A
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- parts
- aging
- peptide
- based composition
- skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses a kind of anti-aging lotion, count in parts by weight, include following component：14.5 16.5 parts of moisturizer, 10.2 13.8 parts of emollient, 2.50 3.50 parts of peptide based composition, 1.70 2.80 parts of skin conditioner, 0.3 0.6 parts of thickener, 1.50 2.50 parts of emulsifying agent, 3.00 4.50 parts of other base-materials, surplus is water.The present invention is using specific compounding than being added to particular kind of peptide based composition in lotion, the molecular weight of the peptide based composition is as low as below 1000 dalton, it is easy to be absorbed by the skin, and it is aided with the components such as the moisturizer of particular types and certain content, emollient, skin conditioner, the lotion being prepared has the anti-aging effects more significantly improved；And final products are without any harmful additive（Such as film forming agent）, will not be damaged to skin tape.Its preparation process is simple, and energy consumption is low, and financial cost is low, green safe, has good prospects for commercial application.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of anti-aging lotion and preparation method thereof.
Background technology
Skin aging is one and cutaneous ultrastructure and the relevant complex process of biochemical change, these changes are interior
The aging of source property（I.e. in human body naturally progressive aging）With it is extrinsic aging（That is the external factor such as environment）Result.
Past five, cosmetics development was little by little turned as the main purpose by the appearance beauty for covering up skin defect during the last ten years
It is changed into health and is integrated as target with beauty.Has there is some of such have specific function, complex new production in the market
Product, this kind of product progressively occupy ascendancy in Cosmetic Market, and wherein anti-aging cosmetics are main representatives.
Major part anti-aging cosmetics is are rapidly achieved effect at present, add in formula various macromolecular functional components or
Film forming agent, on the one hand, cannot effectively be absorbed, resisted since the macromolecular functional component of addition is only capable of staying in skin surface
Aging effects are not notable；On the other hand, since addition is just like polyvinyl alcohol and the film forming agent of albumen, after film forming agent drying into
Film, tensioning the skin, but recover as former state, not having effect not only, also result in skin a degree of damage again after washing away.
Therefore, Cosmetic Market for exploitation the anti-aging product with small molecule functional component or film former-free with
Important realistic meaning and application prospect.
The content of the invention
In view of this, primary and foremost purpose of the invention is to overcome above-mentioned the shortcomings of the prior art, there is provided a kind of effect
Component is easy to be absorbed by the skin, and the anti-aging lotion that anti-aging effects significantly improve.
Another object of the present invention is to provide the preparation method of above-mentioned anti-aging lotion.
The technical solution adopted by the present invention is as follows：
A kind of anti-aging lotion, is counted in parts by weight, includes following component：
14.5-16.5 parts of moisturizer, 10.2-13.8 parts of emollient, 2.50-3.50 parts of peptide based composition, skin conditioner 1.70-
2.80 parts, 0.3-0.6 parts of thickener, 1.50-2.50 parts of emulsifying agent, 3.00-4.50 parts of other base-materials, surplus is water.
As a preferred embodiment of the present invention, the anti-aging lotion, counts, includes following component in parts by weight：
15.0-16.0 parts of moisturizer, 11.5-12.5 parts of emollient, 2.80-3.20 parts of peptide based composition, skin conditioner 2.10-
2.50 parts, 0.4-0.5 parts of thickener, 1.90-2.10 parts of emulsifying agent, 3.60-3.80 parts of other base-materials, surplus is water.
Wherein, the peptide based composition, which is behaved, joins the compound of peptide, sea cucumber peptide and gadus peptide；Contain what is enriched in ginseng peptide
Ginsenoside, is the active ingredient in ginseng, has increase quantity of leucocyte, improves the immunity of the human body, boost metabolism, resists
Aging etc. acts on；Containing a variety of aging ingredients such as SOD in sea cucumber peptide, the oxygen radical in effective scavenger-cell, desalinates color
Spot, recover cytothesis ability；Gadus peptide contains the elastomer for repairing skin fracture, strengthens the tension force and elasticity of skin, thorough
Dispel striae of pregnancy in bottom.Exclude toxin from inside to outside, block melanin to produce, lighten the stain and livid ring around eye.
Three kinds of peptides are compounded, and control ginseng peptide：Sea cucumber peptide：The compounding weight ratio of gadus peptide is 1.25-
1.45：1.00-1.20：0.55-0.70, and the molecular weight of the peptide based composition after compounding is less than 1000 dalton, preferably molecule
Measure as 500-900 dalton.
Only by above-mentioned three kinds of peptides by above-mentioned compounding than carry out compounding use, could cause anti-aging lotion it is effective into
Divide and be easier to be absorbed, anti-aging effects are more notable；When the compounding of above-mentioned three kinds of peptides compares less than 1.25-1.45：1.00-
1.20：0.55-0.70, product beta test process elasticity of skin, skin smooth degree, the colour of skin uniformity, microgroove and wrinkle, glossiness,
The effect unobvious that phenomena such as skin sophistication, the colour of skin are obscure, moisturizing degree improves；It is higher than when the compounding of above-mentioned three kinds of peptides compares
1.25-1.45：1.00-1.20：0.55-0.70, product beta test process elasticity of skin, skin smooth degree, the colour of skin uniformity, microgroove
And the effect and the improvement effect of above-mentioned additive amount that phenomena such as wrinkle, glossiness, skin sophistication, the colour of skin are obscure, moisturizing degree improves
Fruit is suitable, but use cost increase.
Wherein, one or more of the moisturizer in glycerine, propane diols, sorbierite, glycine betaine, hyaluronic acid.
Wherein, the emollient is selected from glycerine polymethacrylates, dimethiconol, ring polydimethylsiloxanes
One or more in alkane, saualane.
Wherein, the thickener is selected from acrylic acid（Ester）One or more in analog copolymer, carbomer.
Wherein, the skin conditioner is selected from german chamomile（CHAMOMILLA RECUTITA）Flower extract, dipotassium glycyrrhizinate,
One or more in magnesium ascorbyl phosphate；The emulsifying agent is the smooth stearate of sorb.
Wherein, other described base-materials include the one or more in ethanol, preservative, chelating agent, pH adjusting agent, essence.
Preferably, the preservative is methyl dihydroxy benzoate；The chelating agent is EDTA disodiums；The pH is adjusted
Agent is potassium hydroxide.
The invention also discloses the preparation method of above-mentioned anti-aging lotion, include the following steps：
（1）By water, most of moisturizer（Glycerine, propane diols, sorbierite, glycine betaine, hyaluronic acid）, part emollient（Glycerine
Polymethacrylates）, thickener, skin conditioner, preservative feed intake, be heated to 80 DEG C, be thoroughly mixed it
Uniformly and it is completely dissolved, is denoted as A groups；
（2）By remaining emollient（Dimethiconol, cyclomethicone, saualane）Thrown with emulsifying agent
Material, is heated to 80 DEG C, it is thoroughly mixed uniformly and A groups are added to after being completely dissolved, homogeneous 3~5 minutes, stirring cooling；
（3）Cooling adds ethanol and peptide based composition is sufficiently mixed, stir evenly at 50 DEG C；
（4）Cooling adds chelating agent and essence is sufficiently mixed, stir evenly, and adjust pH with pH adjusting agent at 35 DEG C
It is worth to 5.5-6.5；
（5）Discharging, after the assay was approved, it is filling packaging, storage be finished product.
Compared with prior art, the present invention have the advantages that：
（1）The present invention is compounded than being added to particular kind of peptide based composition in lotion using specific, the peptide based composition
Molecular weight is easy to be absorbed by the skin as low as below 1000 dalton, and is aided with the moisturizer of particular types and certain content, moisturizing
The components such as agent, skin conditioner, the lotion being prepared have the anti-aging effects more significantly improved.
（2）Gained anti-aging lotion of the invention is good using skin sense, and final products are without any harmful additive（Such as film forming
Agent）, will not be damaged to skin tape.
（3）The preparation process of the present invention is simple, and energy consumption is low, and financial cost is low, green safe, has good commercial Application
Prospect.
Embodiment
The present invention is further illustrated below by embodiment, but embodiments of the present invention and from following realities
Apply the limitation of example.
Raw material used in the embodiment of the present invention and comparative example, but it is not limited only to the following raw material：
Ginseng peptide：Beijing Tai Aitai biotechnologies Co., Ltd；
Sea cucumber peptide：Beijing Tai Aitai biotechnologies Co., Ltd；
Gadus peptide：Beijing Tai Aitai biotechnologies Co., Ltd.
The testing standard or test method of each performance indicator：
The test method of the pH value of lotion:Test method：Method specified in GB/T 13531.1 measures（Dilution method）.
Skin ageing problem improves the evaluation method of degree percentage：The anti-aging lotion of embodiment and comparative example is distinguished
It is supplied to 50 subjects to use product 7 days and 12 days, uses the skin ageing problem after product to improve for subject respectively
The following index of degree makes evaluation, is evaluated by 0-100%, and skin ageing problem improves degree percentage=each target improvement
Degree percentage × corresponding weight/weight summation, and assembly average；Evaluation criterion is as shown in table 1, test result such as table 3
It is shown；
Table 1
The test method of moisture content of skin：Subject 50, face use, first use amount about 0.5ml, along skin pattern
Direction, is slightly massaged outward from inner side, using it is preceding and be respectively adopted after the moisture content of skin moisture tester test skin into
Row contrast, test result are as shown in table 3.
Peptide based composition：
Ginseng peptide, sea cucumber peptide, gadus peptide are uniformly mixed by proportioning table 2 Suo Shi, up to peptide based composition, test performance result is such as
Shown in table 2.
The proportioning (parts by weight) and results of property of 2 peptide based composition of table
Embodiment 1-3 and comparative example 1-4：The preparation of anti-aging lotion
（1）By water, most of moisturizer（Glycerine, propane diols, sorbierite, glycine betaine, hyaluronic acid）, part emollient（Glycerine
Polymethacrylates）, thickener, skin conditioner, preservative feed intake, be heated to 80 DEG C, be thoroughly mixed it
Uniformly and it is completely dissolved, is denoted as A groups；
（2）By remaining emollient（Dimethiconol, cyclomethicone, saualane）Thrown with emulsifying agent
Material, is heated to 80 DEG C, it is thoroughly mixed uniformly and A groups are added to after being completely dissolved, homogeneous 3~5 minutes, stirring cooling；
（3）Cooling adds ethanol and peptide based composition is sufficiently mixed, stir evenly at 50 DEG C；
（4）Cooling adds chelating agent and essence is sufficiently mixed, stir evenly, and adjust pH with pH adjusting agent at 35 DEG C
It is worth to 5.5-6.5；
（5）Discharging, after the assay was approved, it is filling packaging, storage be anti-aging lotion.The performance test of gained anti-aging lotion
The results are shown in Table 3.
Comparative example 5：
According to the proportioning of table 3 by hydrolytic collagen, glycyrrhiza glabra root extract, ursin, tocopherol（Vitamin E）Substitute peptides group
Compound, other are as shown in table 3 with embodiment 1, the performance test results of gained anti-aging lotion.
The proportioning of 3 anti-aging lotion of table（Parts by weight）And testing performance index result
。
Claims (10)
1. a kind of anti-aging lotion, it is characterised in that count in parts by weight, include following component：
14.5-16.5 parts of moisturizer, 10.2-13.8 parts of emollient, 2.50-3.50 parts of peptide based composition, skin conditioner 1.70-
2.80 parts, 0.3-0.6 parts of thickener, 1.50-2.50 parts of emulsifying agent, 3.00-4.50 parts of other base-materials, surplus is water.
2. anti-aging lotion according to claim 1, it is characterised in that count in parts by weight, include following component：
15.0-16.0 parts of moisturizer, 11.5-12.5 parts of emollient, 2.80-3.20 parts of peptide based composition, skin conditioner 2.10-
2.50 parts, 0.4-0.5 parts of thickener, 1.90-2.10 parts of emulsifying agent, 3.60-3.80 parts of other base-materials, surplus is water.
3. anti-aging lotion according to claim 1 or 2, it is characterised in that the peptide based composition, which is behaved, joins peptide, sea cucumber
The compound of peptide and gadus peptide, and ginseng peptide：Sea cucumber peptide：The compounding weight ratio of gadus peptide is 1.25-1.45：1.00-1.20：
0.55-0.70。
4. according to claim 1-3 any one of them anti-aging lotions, it is characterised in that the molecular weight of the peptide based composition
Less than 1000 dalton, preferred molecular weight is 500-900 dalton.
5. anti-aging lotion according to claim 1 or 2, it is characterised in that the moisturizer be selected from glycerine, propane diols,
One or more in sorbierite, glycine betaine, hyaluronic acid.
6. anti-aging lotion according to claim 1 or 2, it is characterised in that the emollient is selected from the poly- methyl-prop of glycerine
One or more in olefin(e) acid ester, dimethiconol, cyclomethicone, saualane.
7. anti-aging lotion according to claim 1 or 2, it is characterised in that the skin conditioner is selected from german chamomile
（CHAMOMILLA RECUTITA）One or more in flower extract, dipotassium glycyrrhizinate, magnesium ascorbyl phosphate.
8. anti-aging lotion according to claim 1 or 2, it is characterised in that the thickener is selected from acrylic acid（Ester）Class
One or more in copolymer, carbomer；The emulsifying agent is the smooth stearate of sorb.
9. anti-aging lotion according to claim 1 or 2, it is characterised in that other described base-materials include ethanol, anti-corrosion
One or more in agent, chelating agent, pH adjusting agent, essence；Preferably, the preservative is methyl dihydroxy benzoate；Institute
It is EDTA disodiums to state chelating agent；The pH adjusting agent is potassium hydroxide.
It is 10. a kind of such as the preparation method of claim 1-9 any one of them anti-aging lotions, it is characterised in that including as follows
Step：
（1）By water, most of moisturizer（Glycerine, propane diols, sorbierite, glycine betaine, hyaluronic acid）, part emollient（Glycerine
Polymethacrylates）, thickener, skin conditioner, preservative feed intake, be heated to 80 DEG C, be thoroughly mixed it
Uniformly and it is completely dissolved, is denoted as A groups；
（2）By remaining emollient（Dimethiconol, cyclomethicone, saualane）Thrown with emulsifying agent
Material, is heated to 80 DEG C, it is thoroughly mixed uniformly and A groups are added to after being completely dissolved, homogeneous 3~5 minutes, stirring cooling；
（3）Cooling adds ethanol and peptide based composition is sufficiently mixed, stir evenly at 50 DEG C；
（4）Cooling adds chelating agent and essence is sufficiently mixed, stir evenly, and adjust pH with pH adjusting agent at 35 DEG C
It is worth to 5.5-6.5；
（5）Discharging, after the assay was approved, it is filling packaging, storage be finished product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810040840.9A CN107951740A (en) | 2018-01-16 | 2018-01-16 | A kind of anti-aging lotion and preparation method thereof |
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| CN201810040840.9A CN107951740A (en) | 2018-01-16 | 2018-01-16 | A kind of anti-aging lotion and preparation method thereof |
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Cited By (3)
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| CN108653000A (en) * | 2018-07-30 | 2018-10-16 | 杨刚刚 | A kind of activity peptide facial mask and preparation method thereof |
| CN113527428A (en) * | 2021-09-17 | 2021-10-22 | 渤海水产育苗(山东)有限公司 | Sea cucumber peptide and application and product thereof |
| CN113578200A (en) * | 2021-06-30 | 2021-11-02 | 广州市泽欣生物科技有限公司 | Preparation process and device for repairing and anti-aging electroactive biomaterial compound |
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Application publication date: 20180424 |