CN108653000A - A kind of activity peptide facial mask and preparation method thereof - Google Patents
A kind of activity peptide facial mask and preparation method thereof Download PDFInfo
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- CN108653000A CN108653000A CN201810851903.9A CN201810851903A CN108653000A CN 108653000 A CN108653000 A CN 108653000A CN 201810851903 A CN201810851903 A CN 201810851903A CN 108653000 A CN108653000 A CN 108653000A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
Abstract
The invention discloses a kind of active peptide facial masks and preparation method thereof.The making raw material of the activity peptide facial mask, the mud mask includes ginseng peptide combinations.The active peptide facial mask of the present invention is wanted active ingredient based on ginseng peptide combinations, and is aided with green-tea extract etc., can effectively remove free radical, delaying skin aging, senile-resistant efficacy is notable, and can inhibit the generation of melanin, it lightens the stain, there is good white-skinned face function.Raw material selected by the present invention is simple and easy to get, cheap, and the cost of manufacture of the reduction facial mask of high degree mitigates the burden of user, and eliminate ginseng peptide smell using tea polyphenols, improves the comfort level of user to the greatest extent.Importantly, the active peptide facial mask of the present invention is free of harmful ingredient, to no skin irritation, and any allergic reaction will not be caused, be a safely and effectively active peptide facial mask.
Description
Technical field
The invention belongs to facial mask preparing technical fields more particularly to a kind of active peptide facial mask and preparation method thereof.
Background technology
Since 21 century, demand of the people to cosmetics is increasing, and facial mask is served as during facial-care
Extremely important role.Facial mask is a kind of carrier of face beautifying health keeping product, when its covering face, can be temporarily isolating extraneous sky
Gas and pollution, increase skin temperature, pore are made to expand, promote the discharge of skin metabolite.It also helps in facial mask simultaneously
Face beautifying health keeping product penetrates into skin surface, generates replenishing water and preserving moisture, whitening and anti-aging and other effects.With the development of science and technology the benefit of facial mask
Water moisturizing, Bearberry Extract are greatly improved, but whitening anti-aging effect is poor always.
And polypeptide has become a kind of most important active constituent at anti crease and anti senile old aspect, and it is new to not only facilitate skin
Old metabolism allows skin just like new life, the colour of skin can be allowed to move ahead along the paces of retroversion with slowing down skin aging.Polypeptide can be improved
Skin tissue regeneration ability can go deep into rapidly epidermis, quickly supplement nutrient, directly activation and skin nutrition cell, energy
The effect of effectively facilitating the metabolism of skin, improving skin pattern, reach anti-aging, whitening.
Invention content
In view of the deficiencies of the prior art, a kind of active peptide facial mask of present invention offer and preparation method thereof.The activity peptide facial mask
With delaying skin aging and white-skinned face function.
Technical scheme is as follows:A kind of activity peptide facial mask, the making raw material of the mud mask includes ginseng peptide
Composition.
Further, weight ratio of the ginseng peptide combinations in mud mask makes raw material is 5~10%, Ke Yigen
It is adjusted according to actual conditions.
Further, the mud mask is made of the raw material of following gravimetric method:5-10 parts of ginseng peptide combinations, green tea carry
Take 3-5 parts of object, 0.2-0.4 parts of vitamin C, 0.2-0.4 parts of vitamin E, 2-4 parts of kaolin, 4-7 parts of mung bean flour, pearl powder
0.5-1 parts, 1-1.5 parts of honey, 0.1-0.3 parts of carbomer, 0.4-0.7 parts of triethanolamine, 0.5-0.8 parts of hyaluronic acid, glycerine
3-5 parts, 0.2-0.6 parts of Compound Resisting microbial inoculum, 0.5-0.8 parts of xanthans, 4-7 parts of 1,2- propylene glycol, 4-6 parts of hydroxyethyl cellulose,
4-6 parts of polysorbate80,0.03-0.05 parts of essence, 43.45-67.37 parts of deionized water.
Preferably, the mud mask is made of the raw material of following parts by weight:8 parts of ginseng peptide combinations, green tea extraction
4 parts of object, 0.3 part of vitamin C, 0.3 part of vitamin E, 3 parts of kaolin, 6 parts of mung bean flour, 0.8 part of pearl powder, 1.2 parts of honey,
0.2 part of carbomer, 0.6 part of triethanolamine, 0.6 part of hyaluronic acid, 4 parts of glycerine, 0.4 part of Compound Resisting microbial inoculum, 0.6 part of xanthans,
6 parts of 1,2- propylene glycol, 5 parts of hydroxyethyl cellulose, 5 parts of polysorbate80,0.04 part of essence, 53.96 parts of deionized water.
The active ingredient of the Compound Resisting microbial inoculum is methyl hydroxybenzoate and bi-imidazolidinyl urea.
Activity peptide facial mask provided by the invention have take out stains, the multiple functions such as freckle removing and whitening, and anti-senescence function is aobvious
It writes.Ginseng peptide is short chain protein, can be absorbed by the skin very well, and the elasticity of skin can also be enhanced, and has very anti-oxidant
Effect, can effectively remove free radical, delaying skin aging;Green-tea extract contains abundant tea polyphenols, has good antioxygen
Change activity, ginseng peptide combinations can be assisted to remove free radical, inhibits B16 cell, enhance the whitening and anti-aging effect of facial mask;
Vitamin C and vitamin E can remove free radical, inhibit the activity of tyrosinase, dispelling stain;Kaolin has good
Oil suction oil-control effect can carry out deep layer cleaning to skin, the grease and dirt accumulated in pore is sucked out;Mung bean flour can remove angle
Matter, anti-inflammatory, Sage Extract, moreover it is possible to improve the obscure colour of skin;Pearl powder can increase skin it is bright and clean with it is elastic, improve skin environment, increase
Strong man's body surface chrotoplast activity, slows down aging;Honey has stronger moistnes, can absorb the moisture in air, prevent table
Skin moisture evaporation can also eliminate blackspot and other facial spots, and have preferable bactericidal effect.
The present invention also provides the preparation methods of the active peptide facial mask, include the following steps:
Step (1) prepares ginseng peptide combinations;
Step (2) weighs ginseng peptide combinations, green-tea extract, vitamin C, triethanolamine, hydroxy ethyl fiber in proportion
Element, polysorbate80, deionized water, are placed in mixer, and heating is stirred, and water phase is made;
Step (3) weighs vitamin E, carbomer, glycerine, Compound Resisting microbial inoculum, 1,2-PD in proportion, is placed in mixer
In, heating is stirred, and oil phase is made;
Step (4) remains temperature-resistant, and oil phase is slowly added in water phase, is stirred;
Step (5) cools down, and is proportionally added into honey, hyaluronic acid, xanthans, essence, is stirred;
Step (6) is proportionally added into kaolin, mung bean flour, pearl powder, is stirred, and lets cool to get active peptide facial mask.
Further, the preparation method of ginseng peptide combinations includes the following steps:
(a) sheet of 5cm thickness is cut into after drying ginseng wash clean, sheet ginseng, which is sent into tumbler, to carry out at tumbling
Reason, when tumbling, vacuumized primary every 10 minutes, exhausted tumbling 15 minutes after vacuum every time, then vacuum pumping, so recycles 3
It is secondary;
(b) ultramicro grinding is carried out, 400 mesh sieve is crossed, ginseng pulverate is obtained and is added in microwave treater, press and ginseng weight ratio
It is 3.2:Distilled water is added in 1.0 amount, and microwave treatment, interval time 8 are spaced under microwave frequency 2500MHz, power 500W
Minute, each microwave treatment 8 minutes is carried out continuously 3 times, then filters, obtains ginseng material residue and filtered fluid;Ginseng material residue is used
Carbon dioxide supercritical extraction takes out soluble ingredient, will be put into blender after the ginseng material residue desolventizing after extraction
In container, filtered fluid is added and is stirred 1 hour under normal temperature condition after adjusting solution ph is 8, forms Ginseng extract;
(c) proteolytic enzyme is added in Ginseng extract and digests 2h, then heat to 95 DEG C, enzyme deactivation 30min is put
It is cold;95 DEG C are warming up to, is sterilized after 10-15min, sodium bicarbonate is added after sterilizing and adjusts pH value to 6.0, alpha-amylase is added
2h is digested with the mixture of compound protease, the compound protease uses Protamex, then heats to 95 DEG C, enzyme deactivation
30min is let cool;Lemon acid for adjusting pH value is added to 4.0, the mixture that pectase and restriction endonuclease is added digests 2h, then heats up
To 95 DEG C, enzyme deactivation 30min lets cool, obtains enzymolysis liquid;The proteolytic enzyme, alpha-amylase, compound protease, pectase,
Restriction endonuclease and the mass ratio of ginseng pulverate are 11:3:5:3:6:960;In enzymolysis process assisting ultrasonic oscillation treatment, ultrasound condition is:
Frequency 65kHz, 1 hour time;
(d) enzymolysis liquid of step (c) is adjusted to neutrality, centrifugation removes precipitation and takes supernatant, selects 350Da and 3500Da
Filter membrane the ginseng peptide of 350Da-3500Da molecular weight in supernatant is detached, being concentrated in vacuo to relative density at 65 DEG C is
1.2 medicinal extract, as ginseng peptide combinations.
Further, step (2) and step (3) are heated to 65~75 DEG C.
Further, step (5) is cooled to 35~45 DEG C.
When above-mentioned mud mask uses:The mud mask prepared is uniformly applied to face, facial mask thickness is with invisible
Skin pattern is advisable, and is washed away after 20min.
It should be noted that people participates in that the ratio of distilled water is added to be that inventor's many experiments obtain optimum value, compare herein
Under example, microwave is best to ginseng shell-broken effect by water, is higher than this ratio, water is very little, and cell cannot be effectively swollen, ginseng-cell
It is interior due to the penetration power of microwave and the insufficient pressure of the water generation of liquid breaks through cell membrane and cell wall, influence broken wall effect
Fruit, and also the water unlike right mind is The more the better, if water is too many, excessive water can cause cell wall inside and outside while rise
Temperature can also influence shell-broken effect.
The present invention is pre-processed ginseng with micronizer using tumbling, is substantially reduced the Microwave Extraction time, is carried
Recovery rate is risen, its main feature is that being decomposed caused by energy saving, saving solvent, the small and avoidable high temperature of pollution.Meanwhile using ultra micro
The method being used in combination with Microwave Extraction is crushed, ginseng active material dissolubility is increased, after changing conventional method extraction, no
It is dissolved in cold water, the characteristic insoluble in common organic solvents.It is 3.2 by with ginseng weight ratio:Distilled water is added in 1.0 amount.
Compared with prior art, the invention has the advantages that:The active peptide facial mask of the present invention is combined with ginseng peptide
Object is principle active component, and be aided with green-tea extract etc., it can effectively remove free radical, delaying skin aging, anti-aging work(
Effect is notable, and can inhibit the generation of melanin, lightens the stain, and has good white-skinned face function.Raw material letter selected by the present invention
It is singly easy to get, cheap, the cost of manufacture of the reduction facial mask of high degree mitigates the burden of user, and disappear using tea polyphenols
In addition to ginseng peptide smell, the comfort level of user is improved to the greatest extent.Importantly, the active peptide facial mask of the present invention is not
Containing harmful ingredient, to no skin irritation, and any allergic reaction will not be caused, be a safely and effectively active
Peptide facial mask.
Specific implementation mode
With reference to specific embodiment, the present invention will be further described.
The reagent used in experimental example is cosmetics rank.
Experimental example 1
5 parts of ginseng peptide combinations, 3 parts of green-tea extract, 0.2 part of vitamin C, 0.2 part of vitamin E, 2 parts of kaolin,
4 parts of mung bean flour, 0.5 part of pearl powder, 1 part of honey, 0.1 part of carbomer, 0.4 part of triethanolamine, 0.5 part of hyaluronic acid, glycerine 3
Part, 0.2 part of Compound Resisting microbial inoculum, 0.5 part of xanthans, 4 parts of 1,2- propylene glycol, 4 parts of hydroxyethyl cellulose, polysorbate80 4
Part, 0.03 part of essence, 67.37 parts of deionized water.
The method for preparing above-mentioned active peptide facial mask, includes the following steps:
(1) ginseng peptide combinations are prepared;
(2) 5 parts of ginseng peptide combinations, 3 parts of green-tea extract, 0.2 part of vitamin C, 0.4 part of triethanolamine, ethoxy are taken
4 parts of cellulose, 4 parts of polysorbate80,67.37 parts of deionized water, are placed in mixer, are heated to 65 DEG C, are stirred,
Water phase is made;
(3) 0.2 part of vitamin E, 0.1 part of carbomer, 3 parts of glycerine, 0.2 part of Compound Resisting microbial inoculum, 4 parts of 1,2-PD are taken,
It is placed in mixer, is heated to 65 DEG C, is stirred, oil phase is made;
(4) it remains temperature-resistant, oil phase is slowly added in water phase, is stirred;
(5) 35 DEG C are cooled to, 1 part of honey, 0.5 part of hyaluronic acid, 0.5 part of xanthans, 0.03 part of essence is added, stirring is mixed
It closes;
(6) 2 parts of kaolin, 4 parts of mung bean flour, 0.5 part of pearl powder is added, is stirred, lets cool to get active peptide facial mask.
Wherein, the preparation method of ginseng peptide combinations includes the following steps:
(a) sheet of 5cm thickness is cut into after drying ginseng wash clean, sheet ginseng, which is sent into tumbler, to carry out at tumbling
Reason, when tumbling, vacuumized primary every 10 minutes, exhausted tumbling 15 minutes after vacuum every time, then vacuum pumping, so recycles 3
It is secondary;
(b) ultramicro grinding is carried out, 400 mesh sieve is crossed, ginseng pulverate is obtained and is added in microwave treater, press and ginseng weight ratio
It is 3.2:Distilled water is added in 1.0 amount, and microwave treatment, interval time 8 are spaced under microwave frequency 2500MHz, power 500W
Minute, each microwave treatment 8 minutes is carried out continuously 3 times, then filters, obtains ginseng material residue and filtered fluid;Ginseng material residue is used
Carbon dioxide supercritical extraction takes out soluble ingredient, will be put into blender after the ginseng material residue desolventizing after extraction
In container, filtered fluid is added and is stirred 1 hour under normal temperature condition after adjusting solution ph is 8, forms Ginseng extract;
(c) proteolytic enzyme is added in Ginseng extract and digests 2h, then heat to 95 DEG C, enzyme deactivation 30min is put
It is cold;95 DEG C are warming up to, is sterilized after 10-15min, sodium bicarbonate is added after sterilizing and adjusts pH value to 6.0, alpha-amylase is added
2h is digested with the mixture of compound protease, the compound protease uses Protamex, then heats to 95 DEG C, enzyme deactivation
30min is let cool;Lemon acid for adjusting pH value is added to 4.0, the mixture that pectase and restriction endonuclease is added digests 2h, then heats up
To 95 DEG C, enzyme deactivation 30min lets cool, obtains enzymolysis liquid;The proteolytic enzyme, alpha-amylase, compound protease, pectase,
Restriction endonuclease and the mass ratio of ginseng pulverate are 11:3:5:3:6:960;In enzymolysis process assisting ultrasonic oscillation treatment, ultrasound condition is:
Frequency 65kHz, 1 hour time;
(d) enzymolysis liquid of step (c) is adjusted to neutrality, centrifugation removes precipitation and takes supernatant, selects 350Da and 3500Da
Filter membrane the ginseng peptide of 350Da-3500Da molecular weight in supernatant is detached, being concentrated in vacuo to relative density at 65 DEG C is
1.2 medicinal extract, as ginseng peptide combinations.
Experimental example 2
8 parts of ginseng peptide combinations, 4 parts of green-tea extract, 0.3 part of vitamin C, 0.3 part of vitamin E, 3 parts of kaolin,
6 parts of mung bean flour, 0.8 part of pearl powder, 1.2 parts of honey, 0.2 part of carbomer, 0.6 part of triethanolamine, 0.6 part of hyaluronic acid, glycerine 4
Part, 0.4 part of Compound Resisting microbial inoculum, 0.6 part of xanthans, 6 parts of 1,2- propylene glycol, 5 parts of hydroxyethyl cellulose, polysorbate80 5
Part, 0.04 part of essence, 53.96 parts of deionized water.
The method for preparing above-mentioned active peptide facial mask, includes the following steps:
(1) ginseng peptide combinations are prepared;
(2) 8 parts of ginseng peptide combinations, 4 parts of green-tea extract, 0.3 part of vitamin C, 0.6 part of triethanolamine, ethoxy are taken
5 parts of cellulose, 5 parts of polysorbate80,53.96 parts of deionized water, are placed in mixer, are heated to 70 DEG C, are stirred,
Water phase is made;
(3) 0.3 part of vitamin E, 0.2 part of carbomer, 4 parts of glycerine, 0.4 part of Compound Resisting microbial inoculum, 6 parts of 1,2-PD are taken,
It is placed in mixer, is heated to 70 DEG C, is stirred, oil phase is made;
(4) it remains temperature-resistant, oil phase is slowly added in water phase, is stirred;
(5) 40 DEG C are cooled to, 1.2 parts of honey, 0.6 part of hyaluronic acid, 0.6 part of xanthans, 0.04 part of essence, stirring is added
Mixing;
(6) 3 parts of kaolin, 6 parts of mung bean flour, 0.8 part of pearl powder is added, is stirred, lets cool to get active peptide facial mask.
Wherein, the preparation method of ginseng peptide combinations is same as Example 1.
Experimental example 3
10 parts of ginseng peptide combinations, 5 parts of green-tea extract, 0.4 part of vitamin C, 0.4 part of vitamin E, 4 parts of kaolin,
7 parts of mung bean flour, 1 part of pearl powder, 1.5 parts of honey, 0.3 part of carbomer, 0.7 part of triethanolamine, 0.8 part of hyaluronic acid, glycerine 5
Part, 0.6 part of Compound Resisting microbial inoculum, 0.8 part of xanthans, 7 parts of 1,2- propylene glycol, 6 parts of hydroxyethyl cellulose, polysorbate80 6
Part, 0.05 part of essence, 43.45 parts of deionized water.
The method for preparing above-mentioned active peptide facial mask, includes the following steps:
(1) ginseng peptide combinations are prepared;
(2) 10 parts of ginseng peptide combinations, 5 parts of green-tea extract, 0.4 part of vitamin C, 0.7 part of triethanolamine, hydroxyl second are taken
6 parts of base cellulose, 6 parts of polysorbate80,43.45 parts of deionized water, are placed in mixer, are heated to 75 DEG C, stirring is mixed
It closes, water phase is made;
(3) 0.4 part of vitamin E, 0.3 part of carbomer, 5 parts of glycerine, 0.6 part of Compound Resisting microbial inoculum, 7 parts of 1,2-PD are taken,
It is placed in mixer, is heated to 75 DEG C, is stirred, oil phase is made;
(4) it remains temperature-resistant, during the oil phase is added to the aqueous phase, is stirred;
(5) 45 DEG C are cooled to, 1.5 parts of honey, 0.8 part of hyaluronic acid, 0.8 part of xanthans, 0.05 part of essence, stirring is added
Mixing;
(6) 4 parts of kaolin, 7 parts of mung bean flour, 1 part of pearl powder is added, is stirred, lets cool to get active peptide facial mask.
Wherein, the preparation method of ginseng peptide combinations is same as Example 1.
Experimental example 4
One, detection method
1, mud mask whitening anti-aging efficacy detection
(1) test material
Active peptide facial mask prepared by embodiment 2;Facial mask 1 (prepares in the method for embodiment 2, does not add ginseng peptide combination
Object), facial mask 2 (is prepared, do not add green-tea extract) in the method for embodiment 2.
(2) test apparatus
Moisture tester, human skin fast optical imaging system, skin elasticity tester Cutometer, skin pigment
Instrument.
(3) subjects
Female subjects 150, year at age (45.3 ± 3.8).
(4) test method
Subject is randomly divided into three experimental group, ginseng peptide control group and green tea control group groupings, every group of each 50 people.It is real
Group active peptide facial mask for using the present invention is tested, ginseng peptide control group uses facial mask 1, green tea control group to use facial mask 2, respectively make sooner or later
With primary, use 3 months altogether.Using pertinent instruments in subject before use, being carried out to index of correlation using 4 weeks, 8 weeks and 12 weeks
It measures.
(5) measurement index
Keratoderma water content:The water content of stratum corneum of cheek position peak is measured using moisture tester, measures 3
It is secondary to be averaged.
Eye microgroove:Eye microgroove is analyzed using human skin fast optical imaging system, including three parameters:
Ra (in the arithmetic mean of instantaneous value of whole testing length range inner outline upward peaks);Rq is (in whole testing length range Internal peripheries
The square root of the average value of line upward peak square);Rz (peak-peak on whole testing length range inner outlines).Three
The smaller skin that represents of parameter is better, and wrinkle is fewer.
Skin elasticity:Skin elasticity is carried out to the non-skin in subject's eye tail portion using skin elasticity tester Cutometer
Measurement, including four parameters:Q1 (elastic force when no negative pressure and maximum tension area ratio when having negative pressure);R2 (no negative pressure
When elastic force and the ratio between maximum tension value when having a negative pressure);R5 (in the first time cycle of skin test, skin recovery process
Elastic part with plus negative pressure process the ratio between elastic part);(in the first time cycle of skin test, skin restored R7
The ratio between the maximum tension amount of the elastic part of journey and skin in current cyclic process).Each parameter measures 3 times respectively, is averaged
Value.Q1, R2, R5 and R7 value illustrate that skin elasticity is better closer to 1.
Pigment content:The pigment content of subject's skin of cheek is analyzed using skin pigment instrument, numerical value is smaller, skin
Skin is more fair and more clear.
2, Stability Determination
The stability of execution standard QB/T2872-2007 measurement facial masks is examined according to cosmetics (facial mask).Heat-resistance test:
Facial mask is placed at (40 ± 1) DEG C and keeps for 24 hours, more whether having notable difference with before experiment after restoring to room temperature;Cold resistance is tried
It tests:Facial mask is placed at (- 10 ± 1) DEG C and keeps for 24 hours, more whether having notable difference with before experiment after restoring to room temperature.
Two, test result
1, facial mask whitening anti-aging effect
Subject is detected using the indices before and after facial mask using pertinent instruments.
Experimental group subject's testing result see the table below:
Ginseng peptide control group subject's testing result see the table below:
Green tea control group subject's testing result see the table below:
By result it is found that the present invention active peptide facial mask keratoderma water content increases after use, eye microgroove subtracts
Few, skin elasticity increases and facial pigmentation content is reduced, active peptide facial mask of the invention have good whitening, moisturizing moisturizing,
Senile-resistant efficacy, especially whitening and anti-aging effect, and active peptide facial mask whitening, moisturizing moisturizing, anti-ageing prepared by experimental group
Old effect is significantly better than ginseng peptide control group and green tea control group, and active peptide facial mask of the invention is to have sternly to component and proportioning
What lattice required, it can not arbitrarily change, otherwise influence the effect of active peptide facial mask.
2, the stability of facial mask
Execution standard QB/T2872-2007 is examined to measure the heat resistance of above-mentioned facial mask and resist cold according to cosmetics (facial mask)
Property, do not occur the wild effects such as water oil layer after as a result showing facial mask heating or cooling, it can be seen that, activity of the invention
Peptide facial mask is with good stability.
Above-described embodiment be the present invention several specific implementation modes, it is intended to help understand the embodiment of the present invention principle and
Preparation method, but embodiment of the present invention are not limited by the above embodiments;Meanwhile for the general technology people of this field
Member, according to the present invention embodiment, the there will be changes in specific implementation mode and application range, in conclusion this explanation
Book content should not be construed as limiting the invention.Moreover, institute under other any Spirit Essences and principle without departing from the present invention
Change, modification, replacement, simplification of work etc. are all included in the scope of protection of the present invention.
Claims (9)
1. a kind of activity peptide facial mask, which is characterized in that the making raw material of the mud mask includes ginseng peptide combinations.
2. activity peptide facial mask as described in claim 1, which is characterized in that the ginseng peptide combinations make former in mud mask
Weight ratio in material is 5~10%.
3. activity peptide facial mask as described in claim 1, which is characterized in that the mud mask by following parts by weight raw material system
At:5-10 parts of ginseng peptide combinations, 3-5 parts of green-tea extract, 0.2-0.4 parts of vitamin C, 0.2-0.4 parts of vitamin E, height
Soil 2-4 parts of ridge, 4-7 parts of mung bean flour, 0.5-1 parts of pearl powder, 1-1.5 parts of honey, 0.1-0.3 parts of carbomer, triethanolamine 0.4-
0.7 part, 0.5-0.8 parts of hyaluronic acid, 3-5 parts of glycerine, 0.2-0.6 parts of Compound Resisting microbial inoculum, 0.5-0.8 parts of xanthans, 1,2- third
4-7 parts of glycol, 4-6 parts of hydroxyethyl cellulose, 4-6 parts of polysorbate80,0.03-0.05 parts of essence, deionized water 43.45-
67.37 parts.
4. activity peptide facial mask as claimed in claim 3, which is characterized in that the mud mask by following parts by weight raw material system
At:8 parts of ginseng peptide combinations, 4 parts of green-tea extract, 0.3 part of vitamin C, 0.3 part of vitamin E, 3 parts of kaolin, mung bean flour
6 parts, it is 0.8 part of pearl powder, 1.2 parts of honey, 0.2 part of carbomer, 0.6 part of triethanolamine, 0.6 part of hyaluronic acid, 4 parts of glycerine, multiple
0.4 part of square antiseptic, 0.6 part of xanthans, 6 parts of 1,2- propylene glycol, 5 parts of hydroxyethyl cellulose, 5 parts of polysorbate80, essence
0.04 part, 53.96 parts of deionized water.
5. activity peptide facial mask as claimed in claim 3, which is characterized in that the Compound Resisting microbial inoculum is by methyl hydroxybenzoate and double imidazoles
Ureine forms.
6. a kind of preparation method of active peptide facial mask as described in any one in claim 1-5, which is characterized in that including following step
Suddenly:
Step (1) prepares ginseng peptide combinations;
Step (2) weighs ginseng peptide combinations, green-tea extract, vitamin C, triethanolamine, hydroxyethyl cellulose, gathers in proportion
Sorbitol ester 80, deionized water, are placed in mixer, and heating is stirred, and water phase is made;
Step (3) weighs vitamin E, carbomer, glycerine, Compound Resisting microbial inoculum, 1,2-PD in proportion, is placed in mixer,
Heating, is stirred, and oil phase is made;
Step (4) remains temperature-resistant, and oil phase is slowly added in water phase, is stirred;
Step (5) cools down, and is proportionally added into honey, hyaluronic acid, xanthans, essence, is stirred;
Step (6) is proportionally added into kaolin, mung bean flour, pearl powder, is stirred, and lets cool to get active peptide facial mask.
7. the preparation method of activity peptide facial mask as claimed in claim 6, which is characterized in that the preparation of the ginseng peptide combinations
Method includes the following steps:
(a) sheet of 5cm thickness is cut into after drying ginseng wash clean, sheet ginseng, which is sent into tumbler, carries out tumbling processing,
It vacuumized every 10 minutes primary when tumbling, exhausts tumbling 15 minutes after vacuum every time, then vacuum pumping, so cycle 3 times;
(b) ultramicro grinding is carried out, 400 mesh sieve is crossed, ginseng pulverate is obtained and is added in microwave treater, be by with ginseng weight ratio
3.2:Distilled water is added in 1.0 amount, and microwave treatment is spaced under microwave frequency 2500MHz, power 500W, and interval time is 8 points
Clock, each microwave treatment 8 minutes are carried out continuously 3 times, then filter, obtain ginseng material residue and filtered fluid;By ginseng material residue with two
Carbonoxide supercritical extract takes out soluble ingredient, will be put into the appearance with blender after the ginseng material residue desolventizing after extraction
In device, filtered fluid is added and is stirred 1 hour under normal temperature condition after adjusting solution ph is 8, forms Ginseng extract;
(c) proteolytic enzyme is added in Ginseng extract and digests 2h, then heat to 95 DEG C, enzyme deactivation 30min is let cool;It rises
Temperature sterilizes to 95 DEG C after 10-15min, and sodium bicarbonate is added after sterilizing and adjusts pH value to 6.0, and alpha-amylase and multiple is added
The mixture of hop protein enzyme digests 2h, and the compound protease uses Protamex, then heats to 95 DEG C, enzyme deactivation 30min is put
It is cold;Lemon acid for adjusting pH value is added to 4.0, the mixture that pectase and restriction endonuclease is added digests 2h, then heats to 95 DEG C, goes out
Enzyme 30min, lets cool, and obtains enzymolysis liquid;The proteolytic enzyme, alpha-amylase, compound protease, pectase, restriction endonuclease and
The mass ratio of ginseng pulverate is 11:3:5:3:6:960;In enzymolysis process assisting ultrasonic oscillation treatment, ultrasound condition is:Frequency
65kHz, 1 hour time;
(d) enzymolysis liquid of step (c) is adjusted to neutrality, centrifugation removes precipitation and takes supernatant, selects the filter of 350Da and 3500Da
Film detaches the ginseng peptide of 350Da-3500Da molecular weight in supernatant, and it is 1.2 that relative density is concentrated in vacuo at 65 DEG C
Medicinal extract, as ginseng peptide combinations.
8. the preparation method of activity peptide facial mask as claimed in claim 6, which is characterized in that step (2) and step (3) are heated to
65~75 DEG C.
9. the preparation method of activity peptide facial mask as claimed in claim 6, which is characterized in that step (5) is cooled to 35~45 DEG C.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111700818A (en) * | 2020-07-14 | 2020-09-25 | 瑞莱茵(北京)生物科技有限责任公司 | Wrinkle-removing and anti-aging ginseng polypeptide toning lotion and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105769601A (en) * | 2016-03-30 | 2016-07-20 | 昆明理工大学 | Walnut enzyme whitening and nourishing mud mask and preparation method thereof |
CN105852136A (en) * | 2016-04-07 | 2016-08-17 | 金寨金栗源生物技术有限公司 | Preparation method of ginseng peptides |
CN105963204A (en) * | 2016-06-27 | 2016-09-28 | 中国人民解放军总医院 | Anti-allergic mask with moisturizing and repairing functions and preparation method of anti-allergic mask |
CN107951740A (en) * | 2018-01-16 | 2018-04-24 | 广州市美姿贺化妆品有限公司 | A kind of anti-aging lotion and preparation method thereof |
-
2018
- 2018-07-30 CN CN201810851903.9A patent/CN108653000A/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105769601A (en) * | 2016-03-30 | 2016-07-20 | 昆明理工大学 | Walnut enzyme whitening and nourishing mud mask and preparation method thereof |
CN105852136A (en) * | 2016-04-07 | 2016-08-17 | 金寨金栗源生物技术有限公司 | Preparation method of ginseng peptides |
CN105963204A (en) * | 2016-06-27 | 2016-09-28 | 中国人民解放军总医院 | Anti-allergic mask with moisturizing and repairing functions and preparation method of anti-allergic mask |
CN107951740A (en) * | 2018-01-16 | 2018-04-24 | 广州市美姿贺化妆品有限公司 | A kind of anti-aging lotion and preparation method thereof |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111700818A (en) * | 2020-07-14 | 2020-09-25 | 瑞莱茵(北京)生物科技有限责任公司 | Wrinkle-removing and anti-aging ginseng polypeptide toning lotion and preparation method thereof |
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