CN103027859A - Cosmetic containing Ganoderma capense glycopeptides, and its application - Google Patents

Cosmetic containing Ganoderma capense glycopeptides, and its application Download PDF

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CN103027859A
CN103027859A CN2011102908972A CN201110290897A CN103027859A CN 103027859 A CN103027859 A CN 103027859A CN 2011102908972 A CN2011102908972 A CN 2011102908972A CN 201110290897 A CN201110290897 A CN 201110290897A CN 103027859 A CN103027859 A CN 103027859A
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cosmetics
ganoderma
glycopeptide
panthenol
skin
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CN103027859B (en
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吉晓月
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BEIJING CELLWAY HEALTH BIOTECHNOLOGY Co Ltd
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BEIJING CELLWAY HEALTH BIOTECHNOLOGY Co Ltd
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Abstract

The invention discloses a new face cosmetic component, a cosmetic based on Ganoderma capense glycopeptides, and an application of the cosmetic component in the cosmetic. New active components comprising Ganoderma capense polysaccharides and polypeptides are extracted from Ganoderma capense through adopting a modern biological technology; and the complex formulation of the Ganoderma capense glycopeptides with other cosmetic active components comprising hyaluronic acid, sodium lactate, sodium pyrrolidonecarboxylate, sweet almond oil, jojoba oil, D-panthenol and the like realizes the synergistic effect, and enables the skin dryness, pruritus, peeling and wrinkles to be well improved, the skin color to be brightened, the elasticity to be increased, the use to be comfortable and safe, and no irritation or extremely-small irritation to skins to be realized.

Description

Contain cosmetics and the application thereof of ganoderma's glycopeptide
Technical field
The present invention relates to a kind of new cosmetic composition and application thereof, relate in particular to a kind of bioactive substance polysaccharide that from the Ganoderma ganoderma capense, extracts and the application of polypeptide (ganoderma's glycopeptide) in cosmetics.
Background technology
After the World War II, economy is slowly recovered in the world wide, along with developing rapidly of oil, chemical industry, in order to cater to people to the pursuit of the beauty and serious hope, take mineral oil as main component, the synthetic cosmetics that add other chemical additives such as spice, pigment are born.Because synthetic cosmetics can be produced in enormous quantities, price is cheaper, and can guarantee stable supply, therefore popularizes rapidly socially.
Cosmetics are according to using the position can be divided into following four classes:
1. skin applies some make up, and refers to face and skin cosmetic.These class cosmetics such as various facial cream, bath agent.
2. hair cosmetic, finger send out cosmetics special-purpose.These class cosmetics such as shampoo, mousse, spraying hair jelly etc.
3. cosmetics mainly refer to the beautifying face product, also comprise the cosmetics of fingernail hair.
4. specific function cosmetics refer to be added with the cosmetics of special role medicine.
For above-mentioned cosmetics, especially health, face etc. make and apply some make up, the types of functionality cosmetics of conducting vigorous propaganda on the market now are not fairly obvious to the actual effect of improving the aspects such as xerosis cutis, peeling, wrinkle, brightness, elasticity, and what have also has zest easily to cause allergy to skin.
Summary of the invention
In order to address the above problem, the invention provides a kind of medicine biological technique that utilizes and filter out the highest thin tree ganoderma of immunocompetence as initiation material from Ganoderma, use sieve technology and isolate the cosmetics that the thin sesame polysaccharide of pharmaceutical grade polypeptide is the main active making.Cosmetics of the present invention can fine xerosis cutis, pruritus, peeling, the wrinkle of improving, and bright color, strengthens elasticity, uses comfortable safety, and are non-stimulated or stimulate very little to skin.
For achieving the above object, the invention provides following technical scheme:
Technical scheme 1.
A kind of face applies some make up, and comprising: ganoderma's glycopeptide is aided with the cosmetic active ingredient that hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil, D-panthenol etc. are generally acknowledged, the substrate preparation that applies some make up forms.
Technical scheme 2.
According to technical scheme 1 described cosmetics, its improvements are that the percentage by weight of described cosmetic active ingredient ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol is:
10% ganoderma's glycopeptide solution 30%~75%,
Hyaluronic acid 5%~30%,
Sodium lactate 1%~20%,
Pyrrolidone sodium carboxylate 10%~25%,
Semen pruni armeniacae oil 2%~50%,
Jojoba oil 2%~70%,
D-panthenol 8%~30%.
Need to prove, in technical scheme 2, only define ganoderma's glycopeptide etc. as the part by weight relation of active component, as for the ratio between cosmetic base and these active component, those skilled in the art can suitably increase according to the general knowledge of oneself or dwindle.In the present invention, bring the active component of technique effect can for technical scheme of the present invention is ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol, especially as the ganoderma's glycopeptide of main active be that a kind of impurity is few, purity and biological activity be high, non agricultural chemical residuum, content of beary metal are low, the pharmaceutical grade ganoderma's glycopeptide that safety and effectiveness are higher.
Technical scheme 3.
According to technical scheme 1 or 2 described cosmetics, described cosmetic base is water, wetting agent, lipid, surfactant, thickening agent and spice.
Technical scheme 4.
According to technical scheme 1 described cosmetics, the dosage form of described cosmetics can be in astringent, facial cream, cleansing milk, facial film, the essence one or more.
Except above-mentioned technical scheme about cosmetic product, the present invention also provides the technical scheme of using about active substance in cosmetics.Specific as follows:
Technical scheme 5.
The application of ganoderma's glycopeptide in cosmetics.
Technical scheme 6.
Ganoderma's glycopeptide is aided with the application in cosmetics of hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol.Refer to that more specifically ganoderma's glycopeptide is composite with material materials such as hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol, the application of the mixture of formation in cosmetics.
Technical scheme 7.
Described ganoderma's glycopeptide derives from the dry mycelium powder of thin sesame, through the molecular weight 6000 daltonian aseptic aqueous solutions of biological extraction and purification acquisition.
For above-mentioned cosmetics, the invention provides following preparation method:
Technical scheme 8.
A kind of preparation method of cosmetics, comprise the steps: that ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol are measured in proportion after, mix with cosmetic base, obtain cosmetics.
Technical scheme 9.
Preparation method according to technical scheme 8 described cosmetics is characterized in that, except described cosmetic base, the percentage by weight of described ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol is:
10% ganoderma's glycopeptide solution 30%~75%,
Hyaluronic acid 5%~30%,
Sodium lactate 1%~20%,
Pyrrolidone sodium carboxylate 10%~25%,
Semen pruni armeniacae oil 2%~50%,
Jojoba oil 2%~70%,
D-panthenol 8%~30%.
Technical scheme 10.
Preparation method according to technical scheme 9 described cosmetics is characterized in that, described cosmetic base is water, wetting agent, lipid, surfactant, thickening agent, antiseptic and spice.
Cosmetics of the present invention can improve xerosis cutis, pruritus, peeling, wrinkle well, bright color, strengthen elasticity, use comfortable safety, and are non-stimulated or zest is atomic to skin.
Ganoderma's glycopeptide is polysaccharide and the polypeptide that extracts from Ganoderma ganoderma capense [Ganoderma capense (Lloyd) Teng] mycelium powder, have the effect of regulating body's immunity, body nonspecific immunity, humoral immunization and cellular immunization are all had facilitation; Have antioxidation, remove oxygen-derived free radicals; In addition, the effects such as the nucleic acid of promotion, protein biosynthesis are still arranged.
Finds that as the Bozhi glycopeptide injection that medicine uses problem skin is had good improvement in clinical practice, can be with the active component that cosmetics circle are generally acknowledged composite and bring into play synergism through human experimentation ganoderma's glycopeptide of the present invention, its effect is increased.
Hyaluronic acid claims again hyaluronic acid matter (HYALURONIC ACID is called for short HA), hyaluronic acid.Be the molecular natural polymer acid mucopolysaccharide of disaccharidase by glucuronic acid-N-acetic acid glucosamine, mean molecule quantity is 100,000 to 1,000 ten thousand dalton (Dalton).It is the tender important foundation material of skin water, itself also is a kind of composition of human body.It has special water retention, can pin the hydrone up to 100 times of weight own, be the best nature moisturizing factor of occurring in nature moisture retention of finding at present, be described as " behind the moisturizing sky " in the skin care products, the sponge that hyaluronic acid is likened to suction of somebody's image.It can improve the skin-nourishing metabolism, and make that skin is tender, smooth, wrinkle removing, increase elasticity, prevent aging, be again good Percutaneous absorption enhancer in moisturizing.But with advancing age, hyaluronic acid synthetic minimizing in vivo, the skin shortage moisture that gradually becomes follows the string and gloss, the catabiosis such as wrinkle occur.
Sodium lactate, molecular formula C 3H 5NaO 3Molecular weight 112.06, colourless or almost colourless transparency liquid, be widely used as the moisturizing agent of skin care item, can make skin keep moisture content, reduce wrinkle, a composition of/4th is sodium lactate in the Person's skin horny layer, it is nature moisturizing factor, sodium lactate is used for cosmetics and can forms hydration shell and prevent the moisture of skin volatilization with other chemical analysis, makes skin keep moisture state, prevents that wrinkle from producing, be widely used as the moisturizing agent of skin care item, can also very effectively treat the disorderly and xerosis cutis symptom of skin function.Lactic acid and lactate also have anti-microbial effect, are applied in the anti-acne product.
Pyrrolidone sodium carboxylate, alias table surface-active agent PCA-Na, L-Glutimic acid sodium, burnt sodium glutamate, L-2-pyrrolidone-5-carboxylic acid sodium.Molecular formula C 5H 6O 3NNa, molecular weight 151.1.PCA-Na also is one of important component of human body natural's Moisture factor, and hygroscopicity is high, and nontoxic, non-stimulated, good stability are desirable natural cosmetic health product, can make skin have wettability, flexibility, elasticity and glossiness.PCA-Na can suppress the oxidasic activity of tyrosine, stops melanoid to deposit in skin, thereby has excellent skin whitening effect.As keratolytic, PCA-Na has good therapeutical effect to the skin psoriasis.
Semen pruni armeniacae oil, Rosaceae, formal name used at school Prunus dulcus, faint yellow oily.The original producton location is rich in oleic acid (olein), protein, mineral, Vitamin A, B1, B2, D, E, is reached fatty acid etc. in the Central Asia, is one of most popular vegetable oil.Semen pruni armeniacae oil more can be protected, nourishes, the discomfort of soft skin, the eczema of releiving except dilute dense pure quintessence oil as fat-soluble solvent, and drying, cracking, allergic skin are had repair.
Jojoba oil, another name Jojoba oil, flaxen oily liquids.Take from the simmondsia fruit, main component is unsaturated fatty acid and higher alcohol, and the Jojoba oil of molecular distillation is colourless, and tasteless transparency liquid can be miscible with the skin ester, very easily be absorbed by the skin, with rear without greasy feeling. good stability and non-oxidizability free from worldly cares are arranged.In addition, Jojoba oil also contains and enriches vitamin, has the effect of nourishing softening skin.Jojoba oil has the characteristic that cuts grease, and fuel-displaced, acne, comedo skin are had reasonable effect.
D-panthenol, molecular formula C 9H 19NO 4, molecular weight 205.25 is precursors of vitamin B5, so claim again dexpanthenol.It is a kind of colourless liquid to little yellow transparent thickness, and the special odor that tool is slight is the wetting agent that gos deep into skin permeation, can stimulate epithelial growth, promotes wound healing, plays antiinflammation.
Cosmetics difference with the prior art of the present invention is, contains ganoderma's glycopeptide in the cosmetics, and composite hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil, D-panthenol component.
The present invention a kind ofly filters out the highest strain thin tree ganoderma of immunocompetence as initiation material from Ganoderma, and the new application of the thin sesame polysaccharide of the pharmaceutical grade that separation and purification goes out polypeptide in cosmetics is novel composing prescription and the new product of cosmetics.Ganoderma's glycopeptide in the product can promote cell well to grow as nutrient substance, and its oxidation resistance can protect again DNA to avoid damage, promotes cell proliferation, and the antagonism epidermis cell is old and feeble.But the two-way immunoregulation effect delaying skin cutin of ganoderma's glycopeptide forms, and reduces the cellular oxidation irritable injure.Ganoderma's glycopeptide and hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, D-panthenol are composite, drying, peeling, pruritus, eczema, microgroove, dark yellow skin there is good effect, can alleviate cosmetics to stimulation and the anaphylaxis of skin, have antiinflammatory, bacteriostasis.Ganoderma's glycopeptide and sodium lactate, Jojoba oil, D-panthenol are composite, the anti-acne successful, and life-time service can also be desalinated pockmark.Ganoderma's glycopeptide and hyaluronic acid, pyrrolidone sodium carboxylate, sodium lactate, Jojoba oil, Semen pruni armeniacae oil, D-panthenol are composite, have good desalination wrinkle, crease-resistant, improve the effects such as skin elasticity, bright color.
The compound proportion of described cosmetics can be: the main active ganoderma's glycopeptide accounts for 30%-75%; Other active substance: hyaluronic acid 5%-30%, sodium lactate 1%-20%, pyrrolidone sodium carboxylate 10%-25%, Semen pruni armeniacae oil 2%-50%, Jojoba oil 2%-70%, D-panthenol 8%-30%.Percentage by weight is between the substrate of cosmetics and the cosmetic active substances (comprising ganoderma's glycopeptide): cosmetic active substances 50%-95%, cosmetic base (water, wetting agent, lipid, surfactant, thickening agent, antiseptic, spice etc.) accounts for 5%-50%.
According to aforementioned proportion, cosmetics can be made the multiple dosage forms such as cosmetic water, facial cream, essence, facial film, cleansing milk.Prescription of the present invention is unique, technological innovation, and successful, safe, effective, comfortable, easy to utilize.
In addition, as the above-mentioned cosmetics that optimal technical scheme uses ganoderma's glycopeptide to prepare, technique effect is better.At " improve xerosis cutis, pruritus, peeling, wrinkle, bright color, strengthen elasticity, use comfortable safety, be non-stimulated or zest is atomic to skin " aspect, has better technique effect.Ganoderma's glycopeptide can with other active component synergism, cause effect to improve rapidly.
The specific embodiment
For those skilled in the art can understand technical scheme of the present invention better, provide following specific embodiment, but these embodiment do not limit protection scope of the present invention.
Embodiment 1 essence
[prescription] (percentage by weight):
Figure BSA00000583998300061
Figure BSA00000583998300071
[method for making]
(1) preparation of ganoderma's glycopeptide solution: take by weighing the dry mycelium powder of ganoderma's glycopeptide 1kg, add water rinse, the centrifuging and taking precipitation.Precipitation adds water 10kg dissolving, and 60 ℃ were heated 4-8 hour, is down to room temperature and regulates pH 5.5~7.0, centrifuging and taking supernatant.Ultrafiltration, aseptic collection molecular weight 6000 dalton's components are ganoderma's glycopeptide solution.
(2) taking by weighing card ripple 941 usefulness glycerol by prescription and batch dissolves.Under agitation add successively ganoderma's glycopeptide solution, pyrrolidone sodium carboxylate, hyaluronic acid, D-panthenol, squalane, sodium lactate, Jojoba oil, imidazolidinyl urea, essence, fully stir and make fully dissolving, mixing, with the pH to 5.5 of triethanolamine regulator solution~6.5, supply the prescription total amount with purified water at last, aseptic filtration, packing is the finished product essence.
Wherein, 10% ganoderma's glycopeptide refers to that percentage by weight is 10% ganoderma's glycopeptide solution.
Embodiment 2 astringent
[prescription] (percentage by weight):
Figure BSA00000583998300072
[method for making]
Take by weighing ganoderma's glycopeptide, sodium lactate, hyaluronic acid, D-panthenol, pyrrolidone sodium carboxylate, Jojoba oil, squalane by prescription, stirring and evenly mixing adds load weighted imidazolidinyl urea, spice again, with adding with stirring, and fully dissolving; Supply at last purified water to 100.The rear aseptic filtration that stirs, packing namely gets the astringent finished product.
Embodiment 3 facial creams
[prescription] (percentage by weight)
Figure BSA00000583998300081
[method for making]
Get first an amount of cream base, according to prescription ganoderma's glycopeptide, pyrrolidone sodium carboxylate, sodium lactate, hyaluronic acid, D-panthenol, Semen pruni armeniacae oil, Jojoba oil, imidazolidinyl urea, spice are added successively, grind pasty state; Whole cream base are added again, stir, packing had both got the cream finished product.
Embodiment 4 cleansing milk
[prescription] (percentage by weight)
Figure BSA00000583998300082
Figure BSA00000583998300091
[method for making]
Imidazolinium betaine, coco-nut oil fatty acid disodium glutamate, pyrrolidone sodium carboxylate, sodium lactate are added in the purified water of 75 ℃ of 20g, stir, it is fully dissolved; Be cooled to 45 ℃, add successively ganoderma's glycopeptide, hyaluronic acid, D-panthenol, Jojoba oil, squalane, imidazolidinyl urea, spice, supply purified water to 100, stir, packing had both got the cleansing milk finished product.
Embodiment 5 facial films
[prescription] (percentage by weight):
[method for making]
Taking by weighing first the card ripple dissolves with glycerol, under agitation add successively ganoderma's glycopeptide, pyrrolidone sodium carboxylate, hyaluronic acid, D-panthenol, Jojoba oil, sodium lactate, squalane, imidazolidinyl urea, essence, continuing to stir dissolves it fully, adjust pH to 5.5-6.5 with triethanolamine, add purified water to 100, mixing.Be sub-packed in the bag that includes the non-woven fabrics mould, tight sealing namely gets the facial film finished product.
Embodiment 6 proof tests
This embodiment is 500 of the female volunteers of different skin quality of 25-50 year, is divided into 5 groups of above-mentioned cosmetics embodiment on probation.Trial state is as follows:
The 1st group: the left face of trier embodiment 1 (essence) on probation 3 months.During this period, 63 dry skin experimenter is well improved, after the skin of microgroove desalination, original intensely dark peeling uses a period of time, it is smooth, fine and smooth, moist, glossy, flexible that skin becomes, the colour of skin also obtains revising, skin effect phenomenon do not occur again, it is healthy beautiful that skin seems; 22 neutral skin experimenters use and feel comfortable, and without glutinous soapy feeling, it is pale, fine and smooth that skin becomes than originally; 15 oily skin experimenters, sensation is used comfortable, and without sticking soapy feeling, also having alleviated original fuel-displaced phenomenon, it is fine and smooth that skin becomes, and do not find any discomfort or stimulation in the use procedure.The somebody uses that skin just has obvious change after 3 days.
The 2nd group: the left face of experimenter embodiment 2 (astringent) on probation 3 months, during this period, the response situation of product and top result of use are basically identical, and just astringent is felt in the process of smearing, express being absorbed by the skin, the effect of moisturizing is very good.There are not irritated or any irritant reaction.
The 3rd group: the left face of experimenter embodiment 3 (facial cream) on probation 3 months, during this period, the trier of dry skin feels that product is fine and smooth, moist, water conservation, and use is felt good, and effect and the 1st winding are near even better.In, the trier of oily skin feels that product is salubrious, non-greasy, result of use is also near with the 1st winding.
The 4th group: the left face of experimenter embodiment 4 (cleansing milk) on probation 3 months, the experimenter feels that skin is not tight, it is sliding to wash rear skin silk.Skin dry, pruritus improves after using a period of time, feels comfortable, without any zest.
The 5th group: the left face of trier embodiment 5 (facial film) on probation 1 month, use once weekly, the more water that skin all shows after each the use is tender, pale, fine and smooth, wrinkle alleviates, and effect is obvious especially.After using a period of time, it is flexible especially that skin becomes, and feels comfortable, has no any untoward reaction.
Embodiment 7 contrast tests
Embodiment 6 proof tests the 2nd, 3,4,5 groups the right face of trier are on probation commercially available with dosage form Korea S brand product astringent, facial cream, cleansing milk and facial film 3 months respectively, carry out simultaneously with left face is on probation.The commercially available brand product indices of comparing result is starkly lower than of the present invention with the dosage form product.
Embodiment 8 does not contain the essence contrast test of ganoderma's glycopeptide
[prescription] (percentage by weight)
Figure BSA00000583998300111
[method for making]
Taking by weighing card ripple 941 usefulness glycerol by prescription and batch dissolves.Under agitation add successively pyrrolidone sodium carboxylate, hyaluronic acid, D-panthenol, squalane, sodium lactate, Jojoba oil, triethanolamine, imidazolidinyl urea, essence, stir, fully aseptic filtration after the dissolving, packing is the finished product essence.
The experimenter that embodiment 6 proof tests are the 1st group is in left face embodiment 1 essence on probation, and the right face essence that does not contain ganoderma's glycopeptide on probation compared test in 3 months.Result of the test shows that the essence indices that does not contain ganoderma's glycopeptide is starkly lower than the essence that the present invention contains ganoderma's glycopeptide, especially to observation index DeGrains such as level and smooth skin, bright color, desalination wrinkle, dry peelings.
More than utilize embodiment to be illustrated to technical scheme of the present invention; the detailed description of these embodiment all is for so that those skilled in the art has comparatively distinct understanding to technical scheme of the present invention, can not be used for limiting protection scope of the present invention.For a person skilled in the art, they can make retouching and improvement to technical scheme of the present invention according to the general knowledge of oneself, will be understood that these retouchings and improvement are contained within protection scope of the present invention.

Claims (9)

1. a face applies some make up, and is aided with the cosmetic active ingredients such as hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil, D-panthenol by ganoderma's glycopeptide, and the substrate preparation that applies some make up forms.
2. cosmetics according to claim 1 is characterized in that, cosmetics of the present invention are as main body take ganoderma's glycopeptide.
According to claim 1 with 2 described cosmetics, it is characterized in that the percentage by weight of described ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol is:
10% ganoderma's glycopeptide solution 30%~75%,
Hyaluronic acid 5%~30%,
Sodium lactate 1%~20%,
Pyrrolidone sodium carboxylate 10%~25%,
Semen pruni armeniacae oil 2%~50%,
Jojoba oil 2%~70%,
D-panthenol 8%~30%.
4. cosmetics according to claim 1 is characterized in that, described cosmetic base is water, wetting agent, lipid, surfactant, thickening agent, antiseptic and spice.
5. cosmetics according to claim 1 is characterized in that, the dosage form of described cosmetics is at least a in astringent, facial cream, cleansing milk, facial film, the essence.
According to claim 1 with 2 described cosmetics, it is characterized in that the application of described ganoderma's glycopeptide in cosmetics.
According to claim 1 with 2 described cosmetics, it is characterized in that the composite application in cosmetics of described ganoderma's glycopeptide and hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol isoreactivity composition.
According to claim 1 with 4 described cosmetics, it is characterized in that described cosmetic base is water, wetting agent, lipid, surfactant, thickening agent, antiseptic and spice.
9. the preparation method of cosmetics, comprise the steps: ganoderma's glycopeptide, hyaluronic acid, sodium lactate, pyrrolidone sodium carboxylate, Semen pruni armeniacae oil, Jojoba oil and D-panthenol and cosmetic base abundant mix homogeneously is in proportion obtained a kind of cosmetics of homogenizing.
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CN105232362A (en) * 2015-07-20 2016-01-13 北京健旭康技术有限公司 Anti-haze cosmetics and preparation technology thereof
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CN104173213A (en) * 2014-07-01 2014-12-03 苏州绿叶日用品有限公司 Moistening composition capable of balancing skin moisture and preparation process of moistening composition capable of balancing skin moisture
CN105232362A (en) * 2015-07-20 2016-01-13 北京健旭康技术有限公司 Anti-haze cosmetics and preparation technology thereof
FR3094642A1 (en) 2019-04-02 2020-10-09 Basf Beauty Care Solutions France Sas New cosmetic use of a glycoprotein extract of Prunus dulcis
FR3103386A1 (en) 2019-04-02 2021-05-28 Basf Beauty Care Solutions France Sas New cosmetic use of a glycoprotein extract of Prunus dulcis

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