CN107889845A

CN107889845A - A kind of pharmaceutical composition for killing planthopper

Info

Publication number: CN107889845A
Application number: CN201711094570.1A
Authority: CN
Inventors: 黄伟
Original assignee: Chengdu Aibike Biotechnology Co Ltd
Current assignee: Chengdu Aibike Biotechnology Co Ltd
Priority date: 2017-11-09
Filing date: 2017-11-09
Publication date: 2018-04-10

Abstract

The invention discloses a kind of pharmaceutical composition for killing planthopper, including fruit of Rangoon creeper's extract, Omphalia extract, pumkin seed P.E, milkwort extract, Herba Senecionis Scandentis extract, benevolence face leaf extract, Rhizoma Bistortae extract, negundo chastetree fruit extract, Flos Magnoliae extract and diazinon.Heretofore described pharmaceutical composition can targetedly kill planthopper, it is and without any side effects to the natural enemy of planthopper, security is good, it is biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body noresidue, the ecological balance is not destroyed, crop growth environment is influenceed small；With preferable permeability and wettability, the central nervous system of polypide is disturbed, suppresses worm's ovum synthesis development, is not susceptible to drug resistance；Quick-acting is good, is adapted to the wide popularization and application in terms of control of insect.

Description

A kind of pharmaceutical composition for killing planthopper

Technical field

The invention belongs to agricultural technology development field, in particular it relates to a kind of pharmaceutical composition for killing planthopper.

Background technology

Chemical agent plays an important role in terms of crop pest control, but the residual of medicine causes nature The ecosystem is worsening, and this has turned into international common concern and key subjects urgently to be resolved hurrily.Since China, twentieth century Because single use chemical pesticide causes agricultural product harmful element exceeded, health and the existence of the people are directly endangered, therefore, state Family pays much attention to and formulated《Medium-term and long-term scientific and technical development program outline》, it is therefore intended that encourage research and development environment-friendly type fertilizer, agriculture Medicine." seeking speed " psychology of current peasant is incompatible, and most farmers are still selected using high poison, the chemical pesticide of high residue, this Chemical pesticide can use only for crop, i.e., kill each class pest for certain crop simultaneously.But this chemical pesticide exists Today of green and environmental protection is advocated, a variety of high poisons and high residue chemicals are limited the quantity or stopped production, further, since insect The difference of species, cause each class pest to occur larger difference in terms of the resistance to the action of a drug and drug resistance, so just make killing for chemical agent Easily there is resistance insect in worm effect, therefore propose to prevent specific insect from just seeming for the insect-proof agent of different insects to have very much must Will, but yet there are no corresponding report.

The content of the invention

It is good that the technical problems to be solved by the invention are to provide a kind of security, biodegradable good, pollution-free and excitant Smell, no environment toxic action, in animal body noresidue, specific aim kill the pharmaceutical composition of planthopper.

Technical scheme is used by the present invention solves above-mentioned technical problem：A kind of pharmaceutical composition for killing planthopper, Including fruit of Rangoon creeper's extract, Omphalia extract, pumkin seed P.E, milkwort extract, Herba Senecionis Scandentis extract, the extraction of benevolence face leaf Thing, Rhizoma Bistortae extract, negundo chastetree fruit extract, Flos Magnoliae extract and diazinon.

In order to which the present invention is better achieved, further, contain per 100ml solution makes equivalent to 14-25g fruit of Rangoon creeper's medicinal materials Gentleman's extract, the Omphalia extract of 14-25g stone-like omphalia medicinal materials, pumkin seed P.E, the 14-25g of 14-25g pumpkin seeds medicinal materials are remote The milkwort extract of will medicinal material, the Herba Senecionis Scandentis extract of 14-25g climbing groundsel medicinal materials, the Ren Mianshu of 14-25g benevolence face leaf medicinal material Leaf extract, the Rhizoma Bistortae extract of 14-25g adder-wort medicinal materials, the negundo chastetree fruit extract of 14-25g fruit of negundo medicinal materials, the 14-25g flower buds of lily magnolia The Flos Magnoliae extract of medicinal material, fruit of Rangoon creeper's extract, Omphalia extract, pumkin seed P.E, milkwort extract, a thousand li light extraction Thing, benevolence face leaf extract, Rhizoma Bistortae extract, negundo chastetree fruit extract, the usage ratio of Flos Magnoliae extract medicinal material are 1：3：1：2： 5：3：1：2：1.

In order to which the present invention is better achieved, further, the dosage of the diazinon is 0.08g~5.0g/100ml.

In order to which the present invention is better achieved, further, the dosage of the diazinon is 0.05g~1.0g/100ml.

In order to which the present invention is better achieved, further, described pharmaceutical composition formulation is powder pin or freezed.

The preparation method of the pharmaceutical composition of above-mentioned killing planthopper is prepared, is comprised the steps：

(1) pharmaceutical composition raw medicinal material fruit of Rangoon creeper 30g, stone-like omphalia 90g, the pumpkin seeds 30g of killing planthopper, polygala 60g, Climbing groundsel 150g, benevolence face leaf 90g, adder-wort 30g, fruit of negundo 60g, flower bud of lily magnolia 30g, diazinon 10g；

(2) fruit of Rangoon creeper, stone-like omphalia, pumpkin seeds add water to cook secondary, 2 hours every time, collecting decoction, add ethanol filtering and concentrating, Add 3 times of amount water, be sufficiently stirred, refrigerate 48 hours, filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, and decoction is standby；

(3) polygala, climbing groundsel, benevolence face leaf, adder-wort, fruit of negundo, the flower bud of lily magnolia add water to cook secondary, 1 hour every time, merge and decoct Liquid, filtration, filtrate is concentrated, is let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, filtrate decompression is concentrated into relatively Density is 1.20, and it is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, it is 1.30 that filtrate, which is concentrated into relative density, adds 3 Amount water again, is sufficiently stirred, and refrigerates 48 hours, filtration, and it is 1.15 that filtrate, which is concentrated into relative density,

(4) merge with above-mentioned all decoctions, add 2 times of amount water, be sufficiently stirred, refrigerate 24 hours, filtration, filtrate adds diazine Phosphorus and deionized water water are configured to 1000ml solution, stir evenly, the relative density when relative density of above-mentioned each filtrate is 80 DEG C；

(5) solution ph is adjusted to 6.5-8.5 with sodium hydroxide solution；

(6) filter, it is filling, sterilizing, produce.

The present invention compared with prior art, has advantages below and beneficial effect：

(1) heretofore described pharmaceutical composition can targetedly kill planthopper, and to the natural enemy of planthopper without Any toxic side effect, security is good, biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body Noresidue, the ecological balance is not destroyed, crop growth environment is influenceed small；

(2) low raw-material cost used in heretofore described pharmaceutical composition, there is preferable permeability and wet Lubricant nature, easily breaks through planthopper wax coat, and depth destroys the epidermal structure of polypide and internal protein, makes planthopper be not easy to send out Raw drug resistance；

(3) heretofore described pharmaceutical composition can interfere with the central nervous system of polypide, suppress worm's ovum synthesis hair Educate；

(4) heretofore described pharmaceutical composition quick-acting is good, and after spray, planthopper stopped eating in 20~40 minutes Death, it is adapted to the wide popularization and application in terms of control of insect.

Embodiment

For the purpose of the present invention, process conditions and advantage effect is more clearly understood, with reference to following embodiment, to this Invention is described in further detail, but the implementation of the present invention is not limited to this, is not departing from the above-mentioned technological thought feelings of the present invention Under condition, according to ordinary skill knowledge and customary means, various replacements and change are made, the model of the present invention all should be included in In enclosing, specific implementation example described herein is not intended to limit the present invention only to explain the present invention.

Embodiment 1：

The present embodiment provides a kind of pharmaceutical composition for killing planthopper, including fruit of Rangoon creeper's extract, Omphalia extract, south It is melon seeds extract, milkwort extract, Herba Senecionis Scandentis extract, benevolence face leaf extract, Rhizoma Bistortae extract, negundo chastetree fruit extract, pungent Smooth extract and diazinon, its component are as follows：

Its preparation method：The fruit of Rangoon creeper, stone-like omphalia, pumpkin seeds add water to cook secondary, 2 hours every time, collecting decoction, add ethanol mistake Filter concentration, add 3 times of amount water, be sufficiently stirred, refrigerate 48 hours, filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, decoction It is standby；Polygala, climbing groundsel, benevolence face leaf, adder-wort, fruit of negundo, the flower bud of lily magnolia add water to cook it is secondary, 1 hour every time, collecting decoction, filter Cross, concentrate filtrate, let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, filtrate decompression is concentrated into relative density For 1.20, it is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, and filtrate is concentrated into relative density as 1.30, adds 3 times of amounts Water, it is sufficiently stirred, refrigerates 48 hours, filtration, filtrate is concentrated into relative density as 1.15；Merge with above-mentioned all decoctions, add 2 times Water is measured, is sufficiently stirred, is refrigerated 24 hours, filtration, filtrate adds diazinon and deionized water water is configured to 1000ml solution, stirs It is even, the relative density when relative density of above-mentioned each filtrate is 80 DEG C；Solution ph is adjusted to 6.5- with sodium hydroxide solution 8.5；Filtering, it is filling, sterilizing, produce.

Wherein, the process for adding ethanol filtering and concentrating is first to filter to get filtrate, and filtrate decompression is concentrated into relative density as 1.27 ~1.30, let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, and decompression filtrate recycling ethanol is simultaneously concentrated into relative Density is 1.30.Filtrate is concentrated into relative density as 1.25~1.30.The mass percent of the sodium hydroxide solution used is 20%.Solution uses filtering with microporous membrane.

Embodiment 2：

The present embodiment verifies that the pharmaceutical composition insecticide common with market is compared, to the eradicative rate of planthopper.

Choose insecticide common on the market：Pale purple purple spore bacterium aqua, nematode killing agent, the agent of special efficacy root line, thiamethoxam disinsection agent.

It is grouped according to different insecticides, every group prepares in worm's ovum, larva, the planthopper of adult three phases respectively Each 1000, insecticide is then used respectively to the planthopper in each stage, tests the eradicative rate of every group of insecticide, it is as follows Shown in table：

Killing effect of the insecticide of table one to planthopper

As seen from the above table, each group insecticide is to larval rice flying lice killing rate highest, and the insecticidal effect of this product is the most Excellent, insect killing effect is notable, and the worm's ovum for being most difficult to kill also has preferable insect killing effect.

Embodiment 3：

The present embodiment verifies eradicative rate of the pharmaceutical composition to various insects.

It is each to choose chafer, beetle, leafhopper, heart-eating worm, pear sucker, scale insect, volume noctuid, mole cricket, fore-telling mud, planthopper 10000, and be grouped respectively, the decoction of same concentrations is made in the medicine being prepared using embodiment 1, respectively the evil to every group Worm is sprayed, and after 1 hour, checks the eradicative rate of various insects, as a result as shown in the table：

Insect killing effect of the medicine of table two to various insects

Group	Eradicative rate (%)
		Planthopper	99.72
Chafer	10.32
		Beetle	9.65
Leafhopper	8.75
		Heart-eating worm	1.02
Pear sucker	0
		Scale insect	0
Roll up noctuid	1.01
		Mole cricket	0
Foretell mud	1.24

As seen from the above table, the medicine that embodiment 1 is prepared, only there is preferable insect killing effect to planthopper, to other evils The insect killing effect of worm is very limited, and thus its specific aim of provable this product is stronger, is only capable of using killing for planthopper.

Claims

1. a kind of pharmaceutical composition for killing planthopper, it is characterised in that including fruit of Rangoon creeper's extract, Omphalia extract, pumpkin Seed extract, milkwort extract, Herba Senecionis Scandentis extract, benevolence face leaf extract, Rhizoma Bistortae extract, negundo chastetree fruit extract, the flower bud of lily magnolia Extract and diazinon.

2. a kind of pharmaceutical composition for killing planthopper according to claim 1, it is characterised in that contain per 100ml solution Omphalia extract, the 14-25g pumpkin seeds of fruit of Rangoon creeper's extract, 14-25g stone-like omphalia medicinal materials equivalent to 14-25g fruit of Rangoon creeper's medicinal materials The pumkin seed P.E of medicinal material, the milkwort extract of 14-25g Polygala tenuifolias, 14-25g climbing groundsel medicinal materials Herba Senecionis Scandentis extract, The benevolence face leaf extract of 14-25g benevolence face leaf medicinal material, the Rhizoma Bistortae extract of 14-25g adder-wort medicinal materials, 14-25g fruit of negundo medicines Negundo chastetree fruit extract, the Flos Magnoliae extract of 14-25g flower bud of lily magnolia medicinal materials of material, fruit of Rangoon creeper's extract, Omphalia extract, pumpkin seeds carry Take thing, milkwort extract, Herba Senecionis Scandentis extract, benevolence face leaf extract, Rhizoma Bistortae extract, negundo chastetree fruit extract, flower bud of lily magnolia extraction The usage ratio of thing medicinal material is 1：3：1：2：5：3：1：2：1.

A kind of 3. pharmaceutical composition for killing planthopper according to claim 1, it is characterised in that the use of the diazinon Measure as 0.08g~5.0g/100ml.

A kind of 4. pharmaceutical composition for killing planthopper according to claim 3, it is characterised in that the use of the diazinon Measure as 0.05g~1.0g/100ml.

5. the pharmaceutical composition of a kind of killing planthopper according to claim 1 ~ 4 any one, it is characterised in that described Medicine composition dosage form is powder pin or freezed.