CN107736408A - It is a kind of to kill the vertical pharmaceutical composition of rice - Google Patents

Abstract

The vertical pharmaceutical composition of rice, including black false hellebore extract, Omphalia extract, Herba Agrimoniae extract, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, madder extract, Radix Gentianae Macrophyllae extract, Flos Magnoliae extract and cycloprothrin are killed the invention discloses a kind of.Heretofore described pharmaceutical composition can targetedly kill rice and indulge, and the natural enemy indulged rice is without any side effects, security is good, it is biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body noresidue, the ecological balance is not destroyed, crop growth environment is influenceed small；With preferable permeability and wettability, the central nervous system of polypide is disturbed, suppresses worm's ovum synthesis development, is not susceptible to drug resistance；Quick-acting is good, is adapted to the wide popularization and application in terms of control of insect.

Description

It is a kind of to kill the vertical pharmaceutical composition of rice

Technical field

The invention belongs to agricultural technology development field, in particular it relates to which a kind of kill the vertical pharmaceutical composition of rice.

Background technology

Chemical agent plays an important role in terms of crop pest control, but the residual of medicine causes nature The ecosystem is worsening, and this has turned into international common concern and key subjects urgently to be resolved hurrily.Since China, twentieth century Because single use chemical pesticide causes agricultural product harmful element exceeded, health and the existence of the people are directly endangered, therefore, state Family pays much attention to and formulated《Medium-term and long-term scientific and technical development program outline》, it is therefore intended that encourage research and development environment-friendly type fertilizer, agriculture Medicine." seeking speed " psychology of current peasant is incompatible, and most farmers are still selected using high poison, the chemical pesticide of high residue, this Chemical pesticide can use only for crop, i.e., kill each class pest for certain crop simultaneously.But this chemical pesticide exists Today of green and environmental protection is advocated, a variety of high poisons and high residue chemicals are limited the quantity or stopped production, further, since insect The difference of species, cause each class pest to occur larger difference in terms of the resistance to the action of a drug and drug resistance, so just make killing for chemical agent Easily there is resistance insect in worm effect, therefore propose to prevent specific insect from just seeming for the insect-proof agent of different insects to have very much must Will, but yet there are no corresponding report.

The content of the invention

It is good that the technical problems to be solved by the invention are to provide a kind of security, biodegradable good, pollution-free and excitant Smell, no environment toxic action, in animal body noresidue, specific aim kill the vertical pharmaceutical composition of rice.

Technical scheme is used by the present invention solves above-mentioned technical problem：It is a kind of to kill the vertical pharmaceutical composition of rice, bag Include black false hellebore extract, Omphalia extract, Herba Agrimoniae extract, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, madder Careless extract, Radix Gentianae Macrophyllae extract, Flos Magnoliae extract and cycloprothrin.

In order to which the present invention is better achieved, further, contain the black false hellebore equivalent to 16-30g black false hellebore medicinal materials per 100ml solution Extract, the Omphalia extract of 16-30g stone-like omphalia medicinal materials, the Herba Agrimoniae extract of 16-30g hairyvein agrimony medicinal materials, 16-30g polygala medicines The milkwort extract of material, the Extract of Euphorbiae of 16-30g moleplant seed medicinal materials, 16-30g Euphorbia lathyris medicinal materials Euphorbia lathyris extract, The madder extract of 16-30g madder medicinal materials, the Radix Gentianae Macrophyllae extract of 16-30g gentiana macrophylla medicines, the flower bud of lily magnolia of 16-30g flower bud of lily magnolia medicinal materials carry Take thing, black false hellebore extract, Omphalia extract, Herba Agrimoniae extract, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, Madder extract, Radix Gentianae Macrophyllae extract, the usage ratio of Flos Magnoliae extract medicinal material are 1：3：1：2：5：3：1：2：1.

In order to which the present invention is better achieved, further, the dosage of the cycloprothrin is 0.08g~5.0g/100ml.

In order to which the present invention is better achieved, further, the dosage of the cycloprothrin is 0.05g~1.0g/100ml.

In order to which the present invention is better achieved, further, described pharmaceutical composition formulation is powder pin or freezed.

The preparation method of the vertical pharmaceutical composition of above-mentioned killing rice is prepared, is comprised the steps：

(1) the vertical pharmaceutical composition raw medicinal material black false hellebore 50g of rice, stone-like omphalia 150g, hairyvein agrimony 50g, polygala 100g, thousand are killed Gold 250g, Euphorbia lathyris 150g, madder 50g, bark of ash 100g, flower bud of lily magnolia 50g, cycloprothrin 20g；

(2) black false hellebore, stone-like omphalia, hairyvein agrimony add water to cook secondary, 2 hours every time, collecting decoction, add ethanol filtering and concentrating, add 3 Amount water again, is sufficiently stirred, and refrigerates 48 hours, and filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, and decoction is standby；

(3) polygala, moleplant seed, Euphorbia lathyris, madder, bark of ash, the flower bud of lily magnolia add water to cook secondary, 1 hour every time, collecting decoction, Filtration, filtrate is concentrated, is let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, filtrate decompression is concentrated into relatively close Spend for 1.20, it is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, and filtrate is concentrated into relative density as 1.30, adds 3 times Water to be measured, is sufficiently stirred, is refrigerated 48 hours, filtration, it is 1.15 that filtrate, which is concentrated into relative density,

(4) merge with above-mentioned all decoctions, add 2 times of amount water, be sufficiently stirred, refrigerate 24 hours, filtration, filtrate adds second cyanogen Chrysanthemum ester and deionized water water are configured to 1000ml solution, stir evenly, relatively close when the relative density of above-mentioned each filtrate is 80 DEG C Degree；

(5) solution ph is adjusted to 6.5-8.5 with sodium hydroxide solution；

(6) filter, it is filling, sterilizing, produce.

The present invention compared with prior art, has advantages below and beneficial effect：

(1) heretofore described pharmaceutical composition can targetedly kill rice and indulge, and the natural enemy indulged rice is without any Toxic side effect, security is good, biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body without residual Thing is stayed, does not destroy the ecological balance, crop growth environment is influenceed small；

(2) low raw-material cost used in heretofore described pharmaceutical composition, there is preferable permeability and wet Lubricant nature, easily break through rice and indulge wax coat, depth destroys the epidermal structure of polypide and internal protein, make rice it is vertical be not susceptible to it is resistance to The property of medicine；

(3) heretofore described pharmaceutical composition can interfere with the central nervous system of polypide, suppress worm's ovum synthesis hair Educate；

(4) heretofore described pharmaceutical composition quick-acting is good, and after spray, rice is indulged to stop eating extremely in 20~40 minutes Die, be adapted to the wide popularization and application in terms of control of insect.

Embodiment

For the purpose of the present invention, process conditions and advantage effect is more clearly understood, with reference to following embodiment, to this Invention is described in further detail, but the implementation of the present invention is not limited to this, is not departing from the above-mentioned technological thought feelings of the present invention Under condition, according to ordinary skill knowledge and customary means, various replacements and change are made, the model of the present invention all should be included in In enclosing, specific implementation example described herein is not intended to limit the present invention only to explain the present invention.

Embodiment 1：

The present embodiment provides a kind of pharmaceutical composition killed rice and indulged, including black false hellebore extract, Omphalia extract, hairyvein agrimony Extract, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, madder extract, Radix Gentianae Macrophyllae extract, Flos Magnoliae extract And cycloprothrin, its component are as follows：

Its preparation method：Black false hellebore, stone-like omphalia, hairyvein agrimony add water to cook secondary, 2 hours every time, collecting decoction, add ethanol to filter Concentration, add 3 times of amount water, be sufficiently stirred, refrigerate 48 hours, filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, and decoction is standby With；Polygala, moleplant seed, Euphorbia lathyris, madder, bark of ash, the flower bud of lily magnolia add water to cook it is secondary, 1 hour every time, collecting decoction, filter, concentration Filtrate, let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, and it is 1.20 that filtrate decompression, which is concentrated into relative density, It is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, and it is 1.30 that filtrate, which is concentrated into relative density, adds 3 times of amount water, fully Stirring, refrigerate 48 hours, filtration, filtrate is concentrated into relative density as 1.15；Merge with above-mentioned all decoctions, add 2 times of amount water, fill Divide stirring, refrigerate 24 hours, filtration, filtrate adds cycloprothrin and deionized water water is configured to 1000ml solution, stirs evenly, above-mentioned The relative density when relative density of each filtrate is 80 DEG C；Solution ph is adjusted to 6.5-8.5 with sodium hydroxide solution；Cross Filter, it is filling, sterilizing, produce.

Wherein, the process for adding ethanol filtering and concentrating is first to filter to get filtrate, and filtrate decompression is concentrated into relative density as 1.27 ~1.30, let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, and decompression filtrate recycling ethanol is simultaneously concentrated into relative Density is 1.30.Filtrate is concentrated into relative density as 1.25~1.30.The mass percent of the sodium hydroxide solution used is 20%.Solution uses filtering with microporous membrane.

Embodiment 2：

The present embodiment verifies that the pharmaceutical composition insecticide common with market is compared, the eradicative rate indulged rice.

Choose insecticide common on the market：Pale purple purple spore bacterium aqua, nematode killing agent, the agent of special efficacy root line, thiamethoxam disinsection agent.

It is grouped according to different insecticides, every group prepares the rice in worm's ovum, larva, adult three phases and indulge respectively respectively It is 1000, then vertical to the rice in each stage to use insecticide respectively, the eradicative rate of every group of insecticide is tested, such as following table institute Show：

The killing effect that the insecticide of table one is indulged rice

As seen from the above table, each group insecticide indulges killing rate highest to larval rice, and the insecticidal effect of this product is the most excellent Good, insect killing effect is notable, and the worm's ovum for being most difficult to kill also has preferable insect killing effect.

Embodiment 3：

The present embodiment verifies eradicative rate of the pharmaceutical composition to various insects.

It is vertical each to choose chafer, beetle, leafhopper, heart-eating worm, pear sucker, scale insect, volume noctuid, mole cricket, fore-telling mud, rice 10000, and be grouped respectively, the decoction of same concentrations is made in the medicine being prepared using embodiment 1, respectively the evil to every group Worm is sprayed, and after 1 hour, checks the eradicative rate of various insects, as a result as shown in the table：

Insect killing effect of the medicine of table two to various insects

Group	Eradicative rate (%)
		Rice is indulged	99.74
Chafer	10.32
		Beetle	9.65
Leafhopper	8.75
		Heart-eating worm	1.02
Pear sucker	0
		Scale insect	0
Roll up noctuid	1.01
		Mole cricket	0
Foretell mud	1.24

As seen from the above table, the medicine that embodiment 1 is prepared, it is only vertical to rice to have preferable insect killing effect, to other insects Insect killing effect it is very limited, thus its specific aim of provable this product is stronger, be only capable of use be used for rice indulge kill.

Claims (5)

1. a kind of kill the vertical pharmaceutical composition of rice, it is characterised in that is carried including black false hellebore extract, Omphalia extract, hairyvein agrimony Take thing, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, madder extract, Radix Gentianae Macrophyllae extract, Flos Magnoliae extract and Cycloprothrin.

2. a kind of pharmaceutical composition killed rice and indulged according to claim 1, it is characterised in that contain phase per 100ml solution When in the black false hellebore extract of 16-30g black false hellebore medicinal materials, the Omphalia extract of 16-30g stone-like omphalia medicinal materials, 16-30g hairyvein agrimony medicinal materials Herba Agrimoniae extract, the milkwort extract of 16-30g Polygala tenuifolias, Extract of Euphorbiae, the 16-30g of 16-30g moleplant seed medicinal materials The bark of ash extraction of the Euphorbia lathyris extract of Euphorbia lathyris medicinal material, the madder extract of 16-30g madder medicinal materials, 16-30g gentiana macrophylla medicines The Flos Magnoliae extract of thing, 16-30g flower bud of lily magnolia medicinal materials, black false hellebore extract, Omphalia extract, Herba Agrimoniae extract, milkwort extract, Extract of Euphorbiae, Euphorbia lathyris extract, madder extract, Radix Gentianae Macrophyllae extract, the usage ratio of Flos Magnoliae extract medicinal material are 1： 3：1：2：5：3：1：2：1.

A kind of 3. pharmaceutical composition killed rice and indulged according to claim 1, it is characterised in that the use of the cycloprothrin Measure as 0.08g~5.0g/100ml.

A kind of 4. pharmaceutical composition killed rice and indulged according to claim 3, it is characterised in that the use of the cycloprothrin Measure as 0.05g~1.0g/100ml.

5. the pharmaceutical composition that a kind of killing rice according to claim 1 ~ 4 any one is indulged, it is characterised in that the medicine Compositions formulation is powder pin or freezed.