CN107836471A - A kind of pharmaceutical composition for killing liriomyza bryoniae - Google Patents

A kind of pharmaceutical composition for killing liriomyza bryoniae Download PDF

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Publication number
CN107836471A
CN107836471A CN201711094547.2A CN201711094547A CN107836471A CN 107836471 A CN107836471 A CN 107836471A CN 201711094547 A CN201711094547 A CN 201711094547A CN 107836471 A CN107836471 A CN 107836471A
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China
Prior art keywords
extract
pharmaceutical composition
liriomyza bryoniae
killing
quarry
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Pending
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CN201711094547.2A
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Chinese (zh)
Inventor
黄伟
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Chengdu Aibike Biotechnology Co Ltd
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Chengdu Aibike Biotechnology Co Ltd
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Priority to CN201711094547.2A priority Critical patent/CN107836471A/en
Publication of CN107836471A publication Critical patent/CN107836471A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10Animals; Substances produced thereby or obtained therefrom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/10Apiaceae or Umbelliferae [Carrot family], e.g. parsley, caraway, dill, lovage, fennel or snakebed
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/12Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/40Liliopsida [monocotyledons]
    • A01N65/42Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pest Control & Pesticides (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a kind of pharmaceutical composition for killing liriomyza bryoniae, including Fructus Carpesii extract, Semen Pharbitidis extract, garlic P.E, Quarry elongated swertia herbs extract, houttuynia extract, Ran She le extract, notopterygium root extract, Semen Myristicae extract, Radix Aristolochiae extract and Osthole.Heretofore described pharmaceutical composition can targetedly kill liriomyza bryoniae, it is and without any side effects to the natural enemy of liriomyza bryoniae, security is good, it is biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body noresidue, the ecological balance is not destroyed, crop growth environment is influenceed small;With preferable permeability and wettability, the central nervous system of polypide is disturbed, suppresses worm's ovum synthesis development, is not susceptible to drug resistance;Quick-acting is good, is adapted to the wide popularization and application in terms of control of insect.

Description

A kind of pharmaceutical composition for killing liriomyza bryoniae
Technical field
The invention belongs to agricultural technology development field, in particular it relates to a kind of pharmaceutical composition for killing liriomyza bryoniae.
Background technology
Chemical agent plays an important role in terms of crop pest control, but the residual of medicine causes nature The ecosystem is worsening, and this has turned into international common concern and key subjects urgently to be resolved hurrily.Since China, twentieth century Because single use chemical pesticide causes agricultural product harmful element exceeded, health and the existence of the people are directly endangered, therefore, state Family pays much attention to and formulated《Medium-term and long-term scientific and technical development program outline》, it is therefore intended that encourage research and development environment-friendly type fertilizer, agriculture Medicine." seeking speed " psychology of current peasant is incompatible, and most farmers are still selected using high poison, the chemical pesticide of high residue, this Chemical pesticide can use only for crop, i.e., kill each class pest for certain crop simultaneously.But this chemical pesticide exists Today of green and environmental protection is advocated, a variety of high poisons and high residue chemicals are limited the quantity or stopped production, further, since insect The difference of species, cause each class pest to occur larger difference in terms of the resistance to the action of a drug and drug resistance, so just make killing for chemical agent Easily there is resistance insect in worm effect, therefore propose to prevent specific insect from just seeming for the insect-proof agent of different insects to have very much must Will, but yet there are no corresponding report.
The content of the invention
It is good that the technical problems to be solved by the invention are to provide a kind of security, biodegradable good, pollution-free and excitant Smell, no environment toxic action, in animal body noresidue, specific aim kill the pharmaceutical composition of liriomyza bryoniae.
Technical scheme is used by the present invention solves above-mentioned technical problem:A kind of pharmaceutical composition for killing liriomyza bryoniae, Including Fructus Carpesii extract, Semen Pharbitidis extract, garlic P.E, Quarry elongated swertia herbs extract, houttuynia extract, the extraction of Ran She le Thing, notopterygium root extract, Semen Myristicae extract, Radix Aristolochiae extract and Osthole.
In order to which the present invention is better achieved, further, contain the Lappula echinata equivalent to 10-25g Lappula echinata medicinal materials per 100ml solution Extract, the Semen Pharbitidis extract of 10-25g kaladana's medicinal material, the garlic P.E of 10-25g garlic medicinal materials, 10-25g Quarry fish courages The Quarry elongated swertia herbs extract of herbal medicine material, the houttuynia extract of 10-25g Herba Houttuyniaes, the boa of 10-25g Ran She le medicinal materials The blue or green wood of le extract, the notopterygium root extract of 10-25g notopterygium root medicinal materials, the Semen Myristicae extract of 10-25g nutmeg medicinal materials, 10-25g The Radix Aristolochiae extract of incense drug material, Fructus Carpesii extract, Semen Pharbitidis extract, garlic P.E, Quarry elongated swertia herbs extract, cordate houttuynia Extract, Ran She le extract, notopterygium root extract, Semen Myristicae extract, the usage ratio of Radix Aristolochiae extract medicinal material are 1:1: 1:3:1:4:1:2:1.
In order to which the present invention is better achieved, further, the dosage of the Osthole is 0.08g~5.0g/100ml.
In order to which the present invention is better achieved, further, the dosage of the Osthole is 0.05g~1.0g/100ml.
In order to which the present invention is better achieved, further, described pharmaceutical composition formulation is powder pin or freezed.
The preparation method of the pharmaceutical composition of above-mentioned killing liriomyza bryoniae is prepared, is comprised the steps:
(1) pharmaceutical composition raw medicinal material Lappula echinata 30g, kaladana 30g, garlic 30g, the Quarry elongated swertia herb of liriomyza bryoniae are killed 90g, cordate houttuynia 30g, Ran She le 120g, notopterygium root 30g, nutmeg 60g, dutchmanspipe root 30g, Osthole 10g;
(2) Lappula echinata, kaladana, garlic add water to cook secondary, 2 hours every time, collecting decoction, add ethanol filtering and concentrating, add 3 Amount water again, is sufficiently stirred, and refrigerates 48 hours, and filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, and decoction is standby;
(3) Quarry elongated swertia herbs, cordate houttuynia, Ran She le, notopterygium root, nutmeg, dutchmanspipe root add water to cook secondary, 1 hour every time, close And decocting liquid, filtration, filtrate is concentrated, is let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, filtrate decompression is concentrated into Relative density is 1.20, and it is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, and it is 1.30 that filtrate, which is concentrated into relative density, Adding 3 times of amount water, be sufficiently stirred, refrigerate 48 hours, filtration, it is 1.15 that filtrate, which is concentrated into relative density,
(4) merge with above-mentioned all decoctions, add 2 times of amount water, be sufficiently stirred, refrigerate 24 hours, filtration, filtrate adds cnidium monnieri Sub- element and deionized water water are configured to 1000ml solution, stir evenly, relatively close when the relative density of above-mentioned each filtrate is 80 DEG C Degree;
(5) solution ph is adjusted to 6.5-8.5 with sodium hydroxide solution;
(6) filter, it is filling, sterilizing, produce.
The present invention compared with prior art, has advantages below and beneficial effect:
(1) heretofore described pharmaceutical composition can targetedly kill liriomyza bryoniae, and to the natural enemy of liriomyza bryoniae without Any toxic side effect, security is good, biodegradable good, pollution-free and penetrating odor, no environment toxic action, in animal body Noresidue, the ecological balance is not destroyed, crop growth environment is influenceed small;
(2) low raw-material cost used in heretofore described pharmaceutical composition, there is preferable permeability and wet Lubricant nature, easily breaks through liriomyza bryoniae wax coat, and depth destroys the epidermal structure of polypide and internal protein, makes liriomyza bryoniae be not easy to send out Raw drug resistance;
(3) heretofore described pharmaceutical composition can interfere with the central nervous system of polypide, suppress worm's ovum synthesis hair Educate;
(4) heretofore described pharmaceutical composition quick-acting is good, and after spray, liriomyza bryoniae was stopped eating in 20~40 minutes Death, it is adapted to the wide popularization and application in terms of control of insect.
Embodiment
For the purpose of the present invention, process conditions and advantage effect is more clearly understood, with reference to following embodiment, to this Invention is described in further detail, but the implementation of the present invention is not limited to this, is not departing from the above-mentioned technological thought feelings of the present invention Under condition, according to ordinary skill knowledge and customary means, various replacements and change are made, the model of the present invention all should be included in In enclosing, specific implementation example described herein is not intended to limit the present invention only to explain the present invention.
Embodiment 1:
The present embodiment provides a kind of pharmaceutical composition for killing liriomyza bryoniae, including Fructus Carpesii extract, Semen Pharbitidis extract, big Garlic extract, Quarry elongated swertia herbs extract, houttuynia extract, Ran She le extract, notopterygium root extract, Semen Myristicae extract, green grass or young crops Radix Aucklandiae extract and Osthole, its component are as follows:
Its preparation method:Lappula echinata, kaladana, garlic add water to cook secondary, 2 hours every time, collecting decoction, add ethanol to filter Concentration, add 3 times of amount water, be sufficiently stirred, refrigerate 48 hours, filtration, it is about 1.15 that filtrate decompression, which is concentrated into relative density, and decoction is standby With;Quarry elongated swertia herbs, cordate houttuynia, Ran She le, notopterygium root, nutmeg, dutchmanspipe root add water to cook it is secondary, 1 hour every time, collecting decoction, Filtration, filtrate is concentrated, is let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, filtrate decompression is concentrated into relatively close Spend for 1.20, it is 70% to add ethanol to make containing amount of alcohol, stands overnight, filters, and filtrate is concentrated into relative density as 1.30, adds 3 times Water is measured, is sufficiently stirred, is refrigerated 48 hours, filtration, filtrate is concentrated into relative density as 1.15;Merge with above-mentioned all decoctions, add 2 Amount water again, is sufficiently stirred, and refrigerates 24 hours, and filtration, filtrate adds Osthole and deionized water water is configured to 1000ml solution, Stir evenly, the relative density when relative density of above-mentioned each filtrate is 80 DEG C;With sodium hydroxide solution adjust solution ph to 6.5-8.5;Filtering, it is filling, sterilizing, produce.
Wherein, the process for adding ethanol filtering and concentrating is first to filter to get filtrate, and filtrate decompression is concentrated into relative density as 1.27 ~1.30, let cool, it is 65% to add ethanol to make containing amount of alcohol, stands overnight, filters, and decompression filtrate recycling ethanol is simultaneously concentrated into relative Density is 1.30.Filtrate is concentrated into relative density as 1.25~1.30.The mass percent of the sodium hydroxide solution used is 20%.Solution uses filtering with microporous membrane.
Embodiment 2:
The present embodiment verifies that the pharmaceutical composition insecticide common with market is compared, to the eradicative rate of liriomyza bryoniae.
Choose insecticide common on the market:Pale purple purple spore bacterium aqua, nematode killing agent, the agent of special efficacy root line, thiamethoxam disinsection agent.
It is grouped according to different insecticides, every group prepares in worm's ovum, larva, the liriomyza bryoniae of adult three phases respectively Each 1000, insecticide is then used respectively to the liriomyza bryoniae in each stage, tests the eradicative rate of every group of insecticide, it is as follows Shown in table:
Killing effect of the insecticide of table one to liriomyza bryoniae
As seen from the above table, each group insecticide is to larval liriomyza bryoniae killing rate highest, and the insecticidal effect of this product is the most Excellent, insect killing effect is notable, and the worm's ovum for being most difficult to kill also has preferable insect killing effect.
Embodiment 3:
The present embodiment verifies eradicative rate of the pharmaceutical composition to various insects.
It is each to choose chafer, beetle, leafhopper, heart-eating worm, pear sucker, scale insect, volume noctuid, mole cricket, fore-telling mud, liriomyza bryoniae 10000, and be grouped respectively, the decoction of same concentrations is made in the medicine being prepared using embodiment 1, respectively the evil to every group Worm is sprayed, and after 1 hour, checks the eradicative rate of various insects, as a result as shown in the table:
Insect killing effect of the medicine of table two to various insects
Group Eradicative rate (%)
Liriomyza bryoniae 99.79
Chafer 10.32
Beetle 9.65
Leafhopper 8.75
Heart-eating worm 1.02
Pear sucker 0
Scale insect 0
Roll up noctuid 1.01
Mole cricket 0
Foretell mud 1.24
As seen from the above table, the medicine that embodiment 1 is prepared, only there is preferable insect killing effect to liriomyza bryoniae, to other evils The insect killing effect of worm is very limited, and thus its specific aim of provable this product is stronger, is only capable of using killing for liriomyza bryoniae.

Claims (5)

1. a kind of pharmaceutical composition for killing liriomyza bryoniae, it is characterised in that including Fructus Carpesii extract, Semen Pharbitidis extract, garlic Extract, Quarry elongated swertia herbs extract, houttuynia extract, Ran She le extract, notopterygium root extract, Semen Myristicae extract, blue or green wood Fragrant extract and Osthole.
2. a kind of pharmaceutical composition for killing liriomyza bryoniae according to claim 1, it is characterised in that contain per 100ml solution Semen Pharbitidis extract, the 10-25g garlic medicines of Fructus Carpesii extract, 10-25g kaladana's medicinal material equivalent to 10-25g Lappula echinata medicinal materials The garlic P.E of material, the Quarry elongated swertia herbs extract of 10-25g Quarry elongated swertia herb medicinal materials, the cordate houttuynia of 10-25g Herba Houttuyniaes carry Take thing, Ran She le extract, the notopterygium root extract of 10-25g notopterygium root medicinal materials, the 10-25g nutmeg medicines of 10-25g Ran She le medicinal materials Semen Myristicae extract, the Radix Aristolochiae extract of 10-25g dutchmanspipe root medicinal materials of material, Fructus Carpesii extract, Semen Pharbitidis extract, garlic Extract, Quarry elongated swertia herbs extract, houttuynia extract, Ran She le extract, notopterygium root extract, Semen Myristicae extract, blue or green wood The usage ratio of fragrant extract medicinal material is 1:1:1:3:1:4:1:2:1.
3. a kind of pharmaceutical composition for killing liriomyza bryoniae according to claim 1, it is characterised in that the Osthole Dosage is 0.08g~5.0g/100ml.
4. a kind of pharmaceutical composition for killing liriomyza bryoniae according to claim 3, it is characterised in that the Osthole Dosage is 0.05g~1.0g/100ml.
5. the pharmaceutical composition of a kind of killing liriomyza bryoniae according to claim 1 ~ 4 any one, it is characterised in that described Medicine composition dosage form is powder pin or freezed.
CN201711094547.2A 2017-11-09 2017-11-09 A kind of pharmaceutical composition for killing liriomyza bryoniae Pending CN107836471A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711094547.2A CN107836471A (en) 2017-11-09 2017-11-09 A kind of pharmaceutical composition for killing liriomyza bryoniae

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711094547.2A CN107836471A (en) 2017-11-09 2017-11-09 A kind of pharmaceutical composition for killing liriomyza bryoniae

Publications (1)

Publication Number Publication Date
CN107836471A true CN107836471A (en) 2018-03-27

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Country Status (1)

Country Link
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