CN107854348A - It is a kind of while there are antipruritic and skin care item of moisture-keeping efficacy and preparation method thereof - Google Patents
It is a kind of while there are antipruritic and skin care item of moisture-keeping efficacy and preparation method thereof Download PDFInfo
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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Abstract
Present invention relates particularly to a kind of while have antipruritic and moisture-keeping efficacy skin care item, the main pharmacodynamics composition of the skin care item includes：The parts by weight of Honegsukle flower P.E 10~25, the parts by weight of shrubby sophora extract 1~10, the parts by weight of hawthorne leaf P.E 0.5~3, the parts by weight of Fructus Kochiae extract 0.1 2.0, the parts by weight of Borneolum Syntheticum extract 0.1~1.0 and the parts by weight of fiery sesame oil 2~12, each effective component cooperates under specific composition and proportioning, collective effect, with preferable antipruritic and moisture-keeping function, extend antipruritic and moisture-keeping function and hold time, reduce access times；By selecting specific surfactant, NMF, emollient, stabilizer, thickener and chelating agent on the basis of above-mentioned effective component, so that the skin care item can deep layer nourish skin, supplement skin moisture, improve skin activity, so as to fundamentally improve skin quality, solves the problems, such as the pruitus of the elderly.
Description
Technical field
The invention belongs to daily chemical product field, and in particular to it is a kind of and meanwhile have antipruritic and skin care item of moisture-keeping efficacy and its
Preparation method.
Background technology
Senile skin pruritus is common in the elderly of more than 60 years old, and initial itch is only limitted to a certain portion of body skin
Position, then extends to body skin large area or whole, due to violent scratching, friction and inadequate stimulus, first can cause and grab
The secondary lesions such as trace, scab, the change of eczema sample, lichenification and pigmentation；Second can also trigger impetigo, epifolliculitis, dothienesis,
The scabies secondary infection such as angioleucitis and lymphnoditis；Three for having such as diabetes, nephrosis and the bed old man that can not be taken care of oneself also
A series of complication can be caused so that aggravating the state of an illness and increase nursing difficulty, it is seen that cutaneous pruritus can seriously reduce the elderly
Quality of life, long-term pruitus even can trigger the mental diseases such as anxiety, depression and fear.Geroderma itch
Except having outside the Pass with some diseases and factor, at the same it is also closely related with the physiological status of the elderly.With advancing age, it is old
Moisture in the moisture and cell of people's body surface gradually decreases, and chronic physiological phenomenon of losing water occurs, then cause dry skin,
Wrinkle increases so that skin is easily stimulated by temperature change, and then induces cutaneous pruritus.
At present, the main method for treating the elderly's cutaneous pruritus is that old application on human skin whole body or local progress moisturizing are stopped
Itch nursing.For pruitus patient, using only the common skin care moisturising product containing moisturizing ingredient, it can only alleviate skin
Symptom is dried, and does not have effect that is immediately antipruritic and repairing skin moisture-keeping ability.Therefore, using antipruritic dual with moisturizing
The cosmetics of effect are the main flow direction that medicine adornment has become domestic and international skin care item, medicine adornment without pigment and using plant extracts as
Main composition, go for any skin quality, especially sensitive skin patient is applicable.
Such as：There is a kind of herbal oxazepan moisturizing emulsion of document report in the prior art, it is carried with Honegsukle flower P.E, kuh-seng
It is main pharmacodynamics composition to take thing, mint extract, Borneolum Syntheticum extract and fructus cannabis oil, and is subject to APG emulsifying agent, palm
Isopropyl propionate, saualane, glycerine, polyacrylate cross-linked polymer -6, allantoin, antioxidant, ultra-violet absorber, preservative
Skin care item are made etc. dispensing, the skin care item have antipruritic and moisture-keeping efficacy to skin.However, above-mentioned skin care item, one side moisturizing
Being held time with itching-relieving action, shorter, access times are more frequent, and another aspect percutaneous permeability is relatively poor, so as to limit
It is applied.
The content of the invention
Therefore, the invention solves first technical problem be existing antipruritic Moisturizer moisturizing and itching-relieving action
Hold time the problem of shorter, access times are more frequent, the invention solves second technical problem be existing antipruritic
The problem of Moisturizer percutaneous permeability is relatively poor, so as to provide a kind of while there is antipruritic and moisture-keeping efficacy skin care
Product, and then its preparation method is provided.
In order to solve the above technical problems, the present invention is achieved through the following technical solutions：
The invention provides a kind of while there is antipruritic and moisture-keeping efficacy composition, including following raw material：Honeysuckle carries
Take the parts by weight of thing 10~25, the parts by weight of shrubby sophora extract 1~10, the parts by weight of hawthorne leaf P.E 0.5~3, Fructus Kochiae extract
0.1-2.0 parts by weight and the parts by weight of Borneolum Syntheticum extract 0.1~1.0, the fiery parts by weight of sesame oil 2~12.
Further, the present invention is above-mentioned while has antipruritic and moisture-keeping efficacy composition, including following raw material：
The parts by weight of Honegsukle flower P.E 14~20, the parts by weight of shrubby sophora extract 4~7, the weight of hawthorne leaf P.E 1~1.5
Part, Fructus Kochiae extract 0.5-1 parts by weight and the parts by weight of Borneolum Syntheticum extract 0.4~0.6, the fiery parts by weight of sesame oil 5~8.
Further, the present invention is above-mentioned while has antipruritic and moisture-keeping efficacy composition, including following raw material：
The parts by weight of Honegsukle flower P.E 14, the parts by weight of shrubby sophora extract 4, the parts by weight of hawthorne leaf P.E 1, fruit of summer cypress extraction
The parts by weight of thing 0.5, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 5；Or
The parts by weight of Honegsukle flower P.E 18, the parts by weight of shrubby sophora extract 5, the parts by weight of hawthorne leaf P.E 1, fruit of summer cypress extraction
The parts by weight of thing 0.5, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 6；Or
The parts by weight of Honegsukle flower P.E 20, the parts by weight of shrubby sophora extract 7, the parts by weight of hawthorne leaf P.E 1.5, the fruit of summer cypress carry
Take the parts by weight of thing 1, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 8；Or
The parts by weight of Honegsukle flower P.E 14, the parts by weight of shrubby sophora extract 7, the parts by weight of hawthorne leaf P.E 1.5, the fruit of summer cypress carry
Take the parts by weight of thing 1, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 7.
The invention provides above-mentioned composition to prepare the application in having the antipruritic and skin care item of moisture-keeping efficacy simultaneously.
Present invention also offers a kind of including having antipruritic and moisture-keeping efficacy skin care item while above-mentioned composition.
The present invention is above-mentioned while has antipruritic and moisture-keeping efficacy skin care item, in addition to following auxiliary material：
The parts by weight of surfactant 1~3, the parts by weight of NMF 2~5, the parts by weight of emollient 3~6, the weight of stabilizer 2~4
Part, the parts by weight of thickener 0.6~0.8, the parts by weight of chelating agent 0.02~0.08.
Further, the surfactant is APG, and the NMF is glycerine, and the emollient is palmitic acid
Isopropyl ester, the stabilizer are caprylic/capric triglyceride, and the thickener is acrylate crosspolymers, the chelating
Agent is disodium ethylene diamine tetraacetate.
The present invention also provides the preparation method of above-mentioned skin care item, comprises the following steps：
(1) plant extracts of selected parts by weight, the increasing for taking the NMF of selected parts by weight, taking selected parts by weight are taken respectively
Thick dose and the chelating agents of selected parts by weight is taken, add suitable quantity of water, be heated to 80-85 DEG C, it is stirring, well mixed, obtain reaction solution A；
(2) the fiery sesame oil of selected parts by weight, the profit for taking the surfactant of selected parts by weight, taking selected parts by weight are taken respectively
Skin agent and the stabilizer for taking selected parts by weight, are heated to 80-85 DEG C, stir to being well mixed, obtain reaction solution B；
(3) 80-85 DEG C of stirring is kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 30-40 DEG C, produces.
Further, the preparation method of the above-mentioned skin care item of the present invention, comprises the following steps：
(1) plant extracts of selected parts by weight, the increasing for taking the NMF of selected parts by weight, taking selected parts by weight are taken respectively
Thick dose and the chelating agents of selected parts by weight is taken, add suitable quantity of water, be heated to 85 DEG C, it is stirring, well mixed, obtain reaction solution A；
(2) the fiery sesame oil of selected parts by weight, the moisturizing for taking the surfactant of selected parts by weight, taking selected weight are taken respectively
Agent and the stabilizer for taking selected parts by weight, are heated to 85 DEG C, stir to being well mixed, obtain reaction solution B；
(3) 85 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 35 DEG C, produces.
Compared with prior art, technical scheme has the following advantages that：
(1) present invention has antipruritic and moisture-keeping efficacy composition, including following raw material simultaneously：Honegsukle flower P.E, hardship
Conopsea extraction, hawthorne leaf P.E, Fructus Kochiae extract, Borneolum Syntheticum extract and fiery sesame oil, by selecting the composition of raw material and matching somebody with somebody
Than, each raw material cooperates under the specific proportioning of specific composition, collective effect, has preferable antipruritic and moisture-keeping function,
Antipruritic and moisture-keeping function is extended to hold time, reduce access times；
(2) present invention has antipruritic and moisture-keeping efficacy composition simultaneously, on Honegsukle flower P.E, shrubby sophora extract, mountain
On the basis of short, bristly hair or beard leaf extract, Fructus Kochiae extract, Borneolum Syntheticum extract, fiery sesame oil, by selecting specific surfactant, guarantor
Humectant, emollient, stabilizer, thickener and chelating agent so that skin care item improve percutaneous permeability made of said composition, from
Deep layer nourishes skin, supplement skin moisture, improves skin activity, so as to fundamentally improve skin quality, solves the skin of the elderly
Itch problem.
Embodiment
In following examples of the present invention and experimental example, all raw materials are commercially available product.
Embodiment 1
The raw material of the skin care item of the present embodiment forms：Honegsukle flower P.E 14g, shrubby sophora extract 4g, leaves of Hawthorn extraction
Thing 1g, Fructus Kochiae extract 0.5g, Borneolum Syntheticum extract 0.5g, fiery sesame oil 5g, APG 1g, glycerine 5g, caprylic/capric glycerine
Three ester 2g, acrylate crosspolymers 0.8g, disodium ethylene diamine tetraacetate 0.02g, isopropyl palmitate 6g；
The preparation method of the skin care item, comprises the following steps：
(1) Honegsukle flower P.E, shrubby sophora extract, hawthorne leaf P.E, the fruit of summer cypress of selected parts by weight is taken to extract respectively
Thing, Borneolum Syntheticum extract, glycerine, acrylate crosspolymers and disodium ethylene diamine tetraacetate, water is added, 85 DEG C is heated to, stirs
Mix, be well mixed, obtain reaction solution A；
(2) fiery sesame oil, APG, isopropyl palmitate and the caprylic/capric triglyceride of selected parts by weight are taken respectively,
85 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；
(3) 85 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 35 DEG C, produces.
Embodiment 2
The raw material of the skin care item of the present embodiment forms：Honegsukle flower P.E 18g, shrubby sophora extract 5g, leaves of Hawthorn extraction
Thing 1g, Fructus Kochiae extract 0.5g, Borneolum Syntheticum extract 0.5g, fiery sesame oil 6g, APG 3g, glycerine 2g, caprylic/capric glycerine
Three ester 4g, acrylate crosspolymers 0.6g, disodium ethylene diamine tetraacetate 0.08g, isopropyl palmitate 3g；
The preparation method of the skin care item, comprises the following steps：
(1) Honegsukle flower P.E, shrubby sophora extract, hawthorne leaf P.E, the fruit of summer cypress of selected parts by weight is taken to extract respectively
Thing, Borneolum Syntheticum extract, glycerine, acrylate crosspolymers and disodium ethylene diamine tetraacetate, water is added, 80 DEG C is heated to, stirs
Mix, be well mixed, obtain reaction solution A；
(2) fiery sesame oil, APG, isopropyl palmitate and the caprylic/capric triglyceride of selected parts by weight are taken respectively,
80 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；
(3) 80 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 40 DEG C, produces.
Embodiment 3
The raw material of the skin care item of the present embodiment forms：Honegsukle flower P.E 20g, shrubby sophora extract 7g, leaves of Hawthorn extraction
Thing 1.5g, Fructus Kochiae extract 1g, Borneolum Syntheticum extract 0.5g, fiery sesame oil 8g, APG 2g, glycerine 4g, caprylic/capric glycerine
Three ester 3g, acrylate crosspolymers 0.7g, disodium ethylene diamine tetraacetate 0.05g, isopropyl palmitate 4g；
The preparation method of the skin care item, comprises the following steps：
(1) Honegsukle flower P.E, shrubby sophora extract, hawthorne leaf P.E, the fruit of summer cypress of selected parts by weight is taken to extract respectively
Thing, Borneolum Syntheticum extract, glycerine, acrylate crosspolymers and disodium ethylene diamine tetraacetate, water is added, 82 DEG C is heated to, stirs
Mix, be well mixed, obtain reaction solution A；
(2) fiery sesame oil, APG, isopropyl palmitate and the caprylic/capric triglyceride of selected parts by weight are taken respectively,
82 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；
(3) 82 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 30 DEG C, produces.
Embodiment 4
The raw material of the skin care item of the present embodiment forms：Honegsukle flower P.E 14g, shrubby sophora extract 7g, leaves of Hawthorn extraction
Thing 1.5g, Fructus Kochiae extract 1g, Borneolum Syntheticum extract 0.5g, fiery sesame oil 7g, APG 2.5g, glycerine 3g, caprylic/capric are sweet
Three ester 2g of oil, acrylate crosspolymers 0.8g, disodium ethylene diamine tetraacetate 0.04g, isopropyl palmitate 5g；
The preparation method of the skin care item, comprises the following steps：
(1) Honegsukle flower P.E, shrubby sophora extract, hawthorne leaf P.E, the fruit of summer cypress of selected parts by weight is taken to extract respectively
Thing, Borneolum Syntheticum extract, glycerine, acrylate crosspolymers and disodium ethylene diamine tetraacetate, 55mL water is added, is heated to 80
DEG C, stir, mix to uniform, obtain reaction solution A；
(2) take respectively selected parts by weight fiery sesame oil, APG, isopropyl palmitate and caprylic/capric triglyceride,
80 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；
(3) 80 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 35 DEG C, produces.
Embodiment 5
The raw material of the skin care item of the present embodiment forms：Honegsukle flower P.E 14g, shrubby sophora extract 7g, leaves of Hawthorn extraction
Thing 1g, Fructus Kochiae extract 1g, Borneolum Syntheticum extract 0.4g, fiery sesame oil 8g, APG 2g, glycerine 5g, caprylic/capric glycerine three
Ester 2g, acrylate crosspolymers 0.7g, disodium ethylene diamine tetraacetate 0.06g, isopropyl palmitate 4g；
The preparation method of the skin care item, comprises the following steps：
(1) Honegsukle flower P.E, shrubby sophora extract, hawthorne leaf P.E, the fruit of summer cypress of selected parts by weight is taken to extract respectively
Thing, Borneolum Syntheticum extract, glycerine, acrylate crosspolymers and disodium ethylene diamine tetraacetate, water is added, 83 DEG C is heated to, stirs
Mix, be well mixed, obtain reaction solution A；
(2) fiery sesame oil, APG, isopropyl palmitate and the caprylic/capric triglyceride of selected parts by weight are taken respectively,
83 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；
(3) 83 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；
(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 38 DEG C, produces.
Experimental example 1Research of the skin care item of the present invention to skin moisture-keeping and antipruritic effect
1st, experiment purpose
Study moisturizing and antipruritic effect of the skin care item of the present invention to skin.
2nd, experimental method
Select dry skin itch patient of 100 age brackets at 30~70 years old, by above-mentioned patient be randomly divided into experimental group,
Control group, every group 50.The smearing method of each group is as follows：Experimental group：Smear skin care item prepared by embodiment 1；Control group：Smear
VE emulsions.During experiment, each group keeps meals and habits and customs unlimited as far as possible, it is impossible to smears other moisturizing antipruritic skin care preparations.
The therapeutic effect of each group is evaluated in this experiment according to following principle：
(1) it is effective：Immediately antipruritic after smearing, smearing once can keep moisture content of skin not within antipruritic 48h, smearing 4h
Become；
(2) effectively：Immediately antipruritic after smearing, smearing once can keep moisture content of skin not within antipruritic 24h, smearing 2h
Become；
(3) it is invalid：Decline without moisture content of skin after obvious antipruritic effect, smearing 0.5h.
3rd, experimental result
The specific experiment result of each group is as shown in table 1.
The specific experiment result of each group of table 1
| Group | Number of cases | Effective number of cases | Effective number of cases | Invalid number of cases | Total effective rate (%) |
| Experimental group | 50 | 36 | 10 | 4 | 92 |
| Control group | 50 | 15 | 4 | 31 | 38 |
As shown in Table 1, the treatment total effective rate of experimental group is 92%, is had compared with the treatment total effective rate of control group aobvious
Write sex differernce；This shows, compared with VE emulsions, moisturizing of the skin care item to skin prepared by embodiment 1 with antipruritic therapeutic effect more
Significantly.
4th, experiment conclusion
Moisturizing of the skin care item of the present invention to skin has the effect of fine with antipruritic.
Experimental example 2Skin care item of the present invention are to skin moisture-keeping and antipruritic persistence, percutaneous permeability effect and safety research
1st, experiment purpose
Study moisturizing of the skin care item of the present invention to skin and antipruritic persistence, percutaneous permeability effect and security.
2nd, experimental method
Select 200 age brackets that above-mentioned patient is randomly divided into experimental group in the dry skin itch patient of 30~70 years old
With positive controls, every group 100.The smearing method of each group is as follows：Experimental group：Smear skin care item prepared by embodiment 1；Control
Group：Smear commercially available herbal oxazepan moisturizing emulsion.During experiment, each group keeps meals and habits and customs unlimited as far as possible, it is impossible to
Smear other moisturizing antipruritic skin care preparations.
3rd, experimental result
The specific experiment result of each group is as shown in table 2.
The specific experiment result of each group of table 2
As shown in Table 2, compared with herbal oxazepan moisturizing emulsion, dimension of the skin care item of the present invention to skin moisture-keeping and itching-relieving action
Hold that the time is longer, and percutaneous permeability is more preferable.
4th, experiment conclusion
Skin care item of the present invention are longer to holding time for skin moisture-keeping and itching-relieving action, and percutaneous permeability effect is more preferable.
Obviously, above-described embodiment is only intended to clearly illustrate example, and is not the restriction to embodiment.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of change or
Change.There is no necessity and possibility to exhaust all the enbodiments.And the obvious change thus extended out or
Among changing still in the protection domain of the invention.
Claims (9)
- It is 1. a kind of while there is antipruritic and moisture-keeping efficacy composition, it is characterised in that including following raw material：Honegsukle flower P.E 10~25 parts by weight, the parts by weight of shrubby sophora extract 1~10, the parts by weight of hawthorne leaf P.E 0.5~3, Fructus Kochiae extract 0.1- 2.0 parts by weight and the parts by weight of Borneolum Syntheticum extract 0.1~1.0, the fiery parts by weight of sesame oil 2~12.
- It is 2. according to claim 1 while there is antipruritic and moisture-keeping efficacy composition, it is characterised in that including following original Material：The parts by weight of Honegsukle flower P.E 14~20, the parts by weight of shrubby sophora extract 4~7, the parts by weight of hawthorne leaf P.E 1~1.5, Skin seed extract 0.5-1 parts by weight and the parts by weight of Borneolum Syntheticum extract 0.4~0.6, the fiery parts by weight of sesame oil 5~8.
- It is 3. according to claim 1 or 2 while there is antipruritic and moisture-keeping efficacy composition, it is characterised in that including with Lower raw material：The parts by weight of Honegsukle flower P.E 14, the parts by weight of shrubby sophora extract 4, the parts by weight of hawthorne leaf P.E 1, Fructus Kochiae extract 0.5 parts by weight, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 5；OrThe parts by weight of Honegsukle flower P.E 18, the parts by weight of shrubby sophora extract 5, the parts by weight of hawthorne leaf P.E 1, Fructus Kochiae extract 0.5 parts by weight, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 6；OrThe parts by weight of Honegsukle flower P.E 20, the parts by weight of shrubby sophora extract 7, the parts by weight of hawthorne leaf P.E 1.5, Fructus Kochiae extract 1 parts by weight, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 8；OrThe parts by weight of Honegsukle flower P.E 14, the parts by weight of shrubby sophora extract 7, the parts by weight of hawthorne leaf P.E 1.5, Fructus Kochiae extract 1 parts by weight, the parts by weight of Borneolum Syntheticum extract 0.5, the parts by weight of fiery sesame oil 7.
- 4. composition the answering in preparing while there are the antipruritic and skin care item of moisture-keeping efficacy described in claim any one of 1-3 With.
- It is 5. a kind of while there are antipruritic and moisture-keeping efficacy skin care item, it is characterised in that including described in claim any one of 1-3 Composition.
- It is 6. according to claim 5 while there are antipruritic and moisture-keeping efficacy skin care item, it is characterised in that also including following Auxiliary material：The parts by weight of surfactant 1~3, the parts by weight of NMF 2~5, emollient 3~6, the parts by weight of stabilizer 2~4, thickener 0.6~0.8 parts by weight, the parts by weight of chelating agent 0.02~0.08.
- It is 7. according to claim 6 while there are antipruritic and moisture-keeping efficacy skin care item, it is characterised in that to live on the surface Property agent is APG, and the NMF is glycerine, and the emollient is isopropyl palmitate, and the stabilizer is octanoic acid/last of the ten Heavenly stems Acid glycerol three ester, the thickener are acrylate crosspolymers, and the chelating agent is disodium ethylene diamine tetraacetate.
- 8. a kind of claim 6 or 7 has the antipruritic and skin care item of moisture-keeping efficacy preparation methods while described, its feature exists In comprising the following steps：(1) plant extracts of selected parts by weight, the thickener for taking the NMF of selected parts by weight, taking selected parts by weight are taken respectively With the chelating agent for taking selected parts by weight, suitable quantity of water is added, 80-85 DEG C is heated to, stirring, is well mixed, obtains reaction solution A；(2) the fiery sesame oil of selected parts by weight, the emollient for taking the surfactant of selected parts by weight, taking selected parts by weight are taken respectively Stabilizer with selected parts by weight are taken, is heated to 80-85 DEG C, stirs to being well mixed, obtains reaction solution B；(3) 80-85 DEG C of stirring is kept to obtain reaction liquid C to dissolving reaction solution B；(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 30-40 DEG C, produces.
- It is 9. according to claim 8 while there are the antipruritic and skin care item of moisture-keeping efficacy preparation methods, it is characterised in that Comprise the following steps：(1) plant extracts of selected parts by weight, the thickener for taking the NMF of selected parts by weight, taking selected parts by weight are taken respectively With the chelating agent for taking selected parts by weight, suitable quantity of water is added, 85 DEG C is heated to, stirring, is well mixed, obtains reaction solution A；(2) the fiery sesame oil of selected parts by weight, the emollient for taking the surfactant of selected parts by weight, taking selected parts by weight are taken respectively With the stabilizer for taking selected parts by weight, 85 DEG C are heated to, stirs to being well mixed, obtains reaction solution B；(3) 85 DEG C of stirrings are kept to obtain reaction liquid C to dissolving reaction solution B；(4) reaction liquid C is added into reaction solution A, stirring is uniform to emulsifying, and is then cooled to 35 DEG C, produces.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109045280A (en) * | 2018-09-10 | 2018-12-21 | 因之彩生物科技（武汉）有限公司 | A kind of topical composition and its application and remedy for external use |
| CN114539259A (en) * | 2022-02-24 | 2022-05-27 | 深圳海创生物科技有限公司 | Active alkaloid compound, radix Sophorae Flavescentis extract and its application in preparing product with skin pruritus resisting effect |
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| CN102430035A (en) * | 2011-12-06 | 2012-05-02 | 北京工商大学 | Chinese medicinal composition and preparation with effects of relieving allergy and itching and preparation methods thereof |
| WO2013149323A1 (en) * | 2012-04-02 | 2013-10-10 | Ntegrity | Natural products for skin care |
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| CN102430035A (en) * | 2011-12-06 | 2012-05-02 | 北京工商大学 | Chinese medicinal composition and preparation with effects of relieving allergy and itching and preparation methods thereof |
| WO2013149323A1 (en) * | 2012-04-02 | 2013-10-10 | Ntegrity | Natural products for skin care |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109045280A (en) * | 2018-09-10 | 2018-12-21 | 因之彩生物科技（武汉）有限公司 | A kind of topical composition and its application and remedy for external use |
| CN114539259A (en) * | 2022-02-24 | 2022-05-27 | 深圳海创生物科技有限公司 | Active alkaloid compound, radix Sophorae Flavescentis extract and its application in preparing product with skin pruritus resisting effect |
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Application publication date: 20180330 |