CN107753332B - A kind of multiple-effect ointment - Google Patents
A kind of multiple-effect ointment Download PDFInfo
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- CN107753332B CN107753332B CN201710990051.7A CN201710990051A CN107753332B CN 107753332 B CN107753332 B CN 107753332B CN 201710990051 A CN201710990051 A CN 201710990051A CN 107753332 B CN107753332 B CN 107753332B
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4993—Derivatives containing from 2 to 10 oxyalkylene groups
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of multiple-effect ointment, the ingredient comprising following parts by weight: 2~4 parts of deionized water, 0.7~0.9 part of polysorbate -60,1.5~2 parts of sorbitan sesquioleate, 4.5~5.5 parts of zinc oxide, 3~4 parts of lithospermum euchromum Royle extract, 1.5~2.5 parts of olea europaea fruit extract, PhytosootheTM1.5~2.5 parts, 7~9 parts of antipruritic of 9766 phytosterol of LS, wherein the antipruritic is at least one of caprylic/capric triglyceride, lecithin, Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Semen Myristicae extract.Unique emulsifier is used in ointment formulation of the present invention, active constituent can be made to be dispersed in ointment, be formed stable emulsification system；It is added to various active Effect raw material, has and repairs wound, lip care, eczema, chapped skin, chafing, bite by mosquitos, convergent miraculous effects.
Description
Technical field
The present invention relates to a kind of ointment, especially a kind of multiple-effect ointment.
Background technique
As the improvement of people's living standards, people increasingly pay attention to the beauty of appearance appearance, and skin problem is also always
It pays close attention to the most.Since beauty and skin care becomes what women instantly pursued the most, but for a long time, due to anxious for success
It beautifies and eager for instant success and quick profits product design, many skin-protection products is made to have moved towards serious mistaken ideas, moreover, majority skin-protection product at present
Effect is single, if reaching multiple efficacies, needs to be caused using multiple product simultaneously and used upper inconvenience；In addition, ointment
Class product is there is also skin sense is greasy, the bad problem of use feeling.
Summary of the invention
Based on this, a kind of multiple-effect ointment is provided it is an object of the invention to overcome above-mentioned the deficiencies in the prior art place.
To achieve the above object, the technical solution used in the present invention are as follows: a kind of multiple-effect ointment includes following parts by weight
Ingredient: 2~4 parts of deionized water, 0.7~0.9 part of polysorbate -60,1.5~2 parts of sorbitan sesquioleate, zinc oxide
4.5~5.5 parts, 3~4 parts of lithospermum euchromum Royle extract, 1.5~2.5 parts of olea europaea fruit extract, PhytosootheTM LS 9766
1.5~2.5 parts of phytosterol, 7~9 parts of antipruritic, wherein the antipruritic is caprylic/capric triglyceride, lecithin, stone
At least one of Herba Moslae extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Semen Myristicae extract.
The present invention is a ointment with multiple efficacies, and emulsifier (polysorbate -60 and sorb are added in formula
Smooth sesquioleate), it can be very good each active constituent in emulsification ointment, stable lotion be made；Skin is added in formula
Feel regulator (starch ocentyl succinic aluminium), formula can be made dryer and comfortableer；Various active Effect raw material is combined in formula
(zinc oxide, lithospermum euchromum Royle extract, olea europaea fruit extract, PhytosootheTM9766 phytosterol of LS, antipruritic), make
Obtaining product, (zinc oxide is as astringent with multiple efficacies；Lithospermum euchromum Royle extract, olea europaea fruit extract have anti-well
Scorching effect；PhytosootheTM9766 phytosterol of LS is a kind of active additive), product may be used as face cream, hand lotion,
Stern protection cream, lip-stick, trauma agent/ointment etc., product have repair wound, lip care, eczema, chapped skin, chafing, bite by mosquitos,
Convergent miraculous effects.
Preferably, the antipruritic is Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Pork and beans
The compounding of cool extract.
Present inventor can play synergy by a large amount of creative exploration discoveries, above-mentioned four kinds of ingredients compounding
Effect, reach better antipruritic effect.
It is highly preferred that the Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, nutmeg extract
The weight ratio of object are as follows: Mosla chinensis extract: ampelopsis grossdentata leaf extract: puncture vine berry extract: Semen Myristicae extract=1:2:
1:1。
Present inventor can further play association by a large amount of creative exploration discoveries, above-mentioned four kinds of ingredients compounding
With the effect of synergy, reach best antipruritic effect.
Preferably, the ointment also includes the starch ocentyl succinic aluminium of 2~4 parts by weight.It is added in ointment above-mentioned
The starch ocentyl succinic aluminium of content can be very good the skin sense for adjusting ointment, product made to have good dry and comfortable skin sense, into
One step more easily absorbs product.
Preferably, the ointment also includes the saualane of 14~15 parts by weight.
Saualane is that rare chemical stability is high, and the splendid animal fat of use feeling has preferable compatibility to skin,
It will not cause allergy and stimulation, and other active components in formula can be accelerated to permeate into skin；With lower polarity in
Deng spreadability, and pure, colourless, free from extraneous odour；It may also suppress the growth of mould.The saualane of certain content in the present invention, no
Only there is said effect, can also further promote the absorption of other compositions, while form each ingredient in the ointment surely
Determine system.
Preferably, the ointment also includes the tocopherol acetate of 2~3 parts by weight.Tocopherol acetate is vitamin E,
The readily oxidizable substances such as cell membrane and intracellular unsaturated fatty acid are prevented to be oxidized during body metabolism, to protect
The effect that is complete and then preventing aging of cell membrane；The tocopherol acetate of certain content of the present invention can not only give full play to
Its effect, additionally aiding makes each ingredient in ointment form stabilising system, it is played respective function with other active components jointly
Effect, and then achieve the effect that multiple efficacies.
Preferably, the weight ratio of the lithospermum euchromum Royle extract and olea europaea fruit extract are as follows: lithospermum euchromum Royle extract: oil
Olive berry extract=3.5:2.
Lithospermum euchromum Royle extract: cool blood, promoting blood circulation, promoting eruption of detoxifying are used for blood-heat and toxin exuberance, atropurpureus macula, measles without adequate eruption, sore
The treatment of ulcer, eczema, scald；Olea europaea fruit extract has preferable antibacterial effect；The lithospermum euchromum Royle of above-mentioned weight ratio
Extract and olea europaea fruit extract can play synergistic effect, reach better anti-inflammatory, antibacterial effect.
Preferably, the ointment also includes the thickener of following parts by weight: 34~36 parts of microwax, atoleine 7~9
Part, 5~7 parts of cera alba.
The thickener of mentioned component and content can be acted on preferably with emulsifier, make each stable components in the ointment
In the presence of.
Preferably, the ointment also includes the (behenic acid/isostearic acid/dodecane two of glycerol three of 2.5~3.5 parts by weight
Acid) ester.
Preferably, the ointment include following parts by weight ingredient: 3 parts of deionized water, 0.8 part of polysorbate -60,
1.8 parts of sorbitan sesquioleate, 5 parts of zinc oxide, 3.5 parts of lithospermum euchromum Royle extract, 2 parts of olea europaea fruit extract,
PhytosootheTM2 parts of 9766 phytosterol of LS, 8 parts of antipruritic, 3 parts of starch ocentyl succinic aluminium, 14.4 parts of saualane,
2.5 parts of tocopherol acetate, wherein the antipruritic is Mosla chinensis extract, ampelopsis grossdentata leaf extract, the extraction of puncture vine fruit
The compounding of object, Semen Myristicae extract.
In addition, in ointment of the present invention other some adjuvants can also be added according to actual needs, as freshener,
Emulsifier etc..
Compared with the existing technology, the invention has the benefit that
Unique emulsification collocation technology is used in ointment formulation of the present invention, and a small amount of water composition can be made to be dispersed in ointment
In, form stable emulsification system；Due to being added to starch ocentyl succinic aluminium in ointment, product has good dry and comfortable
Skin sense, product more easily absorb；Various active Effect raw material is added in product, may be used as face cream, hand lotion, stern protection cream,
Lip-stick, trauma agent/ointment etc., product, which has, repairs wound, lip care, eczema, chapped skin, chafing, bite by mosquitos, convergent
Miraculous effects.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of embodiment of multiple-effect ointment of the present invention, multiple-effect ointment described in the present embodiment include following parts by weight at
Point:
3 parts of deionized water, 0.8 part of polysorbate -60,1.8 parts of sorbitan sesquioleate, 5 parts of zinc oxide, Xinjiang
3.5 parts of Radix Arnebiae extract, 2 parts of olea europaea fruit extract, PhytosootheTM2 parts of 9766 phytosterol of LS, 8 parts of antipruritic,
3 parts of starch ocentyl succinic aluminium, 14.4 parts of saualane, 2.5 parts of tocopherol acetate, 35 parts of microwax, 8 parts of atoleine,
6 parts of cera alba, glycerol three (behenic acid/isostearic acid/dodecanedioic acid) 3 parts of ester, 0.8 part of menthol, cetearyl glucose
1.2 parts of glycosides.
Wherein, the antipruritic is caprylic/capric triglyceride, lecithin, Mosla chinensis extract, ampelopsis grossdentata leaf mention
Take the compounding of object, puncture vine berry extract, Semen Myristicae extract, the Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine
The weight ratio of berry extract, Semen Myristicae extract are as follows: Mosla chinensis extract: ampelopsis grossdentata leaf extract: puncture vine berry extract:
Semen Myristicae extract=1:2:1:1.
Embodiment 2
A kind of embodiment of multiple-effect ointment of the present invention, multiple-effect ointment described in the present embodiment include following parts by weight at
Point:
It is 2 parts of deionized water, 0.7 part of polysorbate -60,1.5 parts of sorbitan sesquioleate, 4.5 parts of zinc oxide, new
3 parts of boundary Radix Arnebiae extract, 1.5 parts of olea europaea fruit extract, PhytosootheTM1.5 parts of 9766 phytosterol of LS, antipruritic 7
It is part, 2 parts of starch ocentyl succinic aluminium, 14 parts of saualane, 2 parts of tocopherol acetate, 34 parts of microwax, 7 parts of atoleine, white
5 parts of beeswax, glycerol three (behenic acid/isostearic acid/dodecanedioic acid) 2.5 parts of ester, 0.8 part of menthol, cetearyl glucose
1.2 parts of glycosides；
Wherein, the antipruritic is caprylic/capric triglyceride, the compounding of lecithin.
Embodiment 3
A kind of embodiment of multiple-effect ointment of the present invention, multiple-effect ointment described in the present embodiment include following parts by weight at
Point:
4 parts of deionized water, 0.9 part of polysorbate -60,2 parts of sorbitan sesquioleate, 5.5 parts of zinc oxide, Xinjiang
4 parts of Radix Arnebiae extract, 2.5 parts of olea europaea fruit extract, PhytosootheTM2.5 parts of 9766 phytosterol of LS, antipruritic 9
It is part, 4 parts of starch ocentyl succinic aluminium, 15 parts of saualane, 3 parts of tocopherol acetate, 36 parts of microwax, 9 parts of atoleine, white
7 parts of beeswax, glycerol three (behenic acid/isostearic acid/dodecanedioic acid) 3.5 parts of ester, 0.8 part of menthol, cetearyl glucose
1.2 parts of glycosides；
Wherein, the antipruritic is Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, nutmeg
The compounding of extract, the Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Semen Myristicae extract
Weight ratio are as follows: Mosla chinensis extract: ampelopsis grossdentata leaf extract: puncture vine berry extract: Semen Myristicae extract=1:2:1:1.
Embodiment 4
Moisturizing, moisture-keeping function test
The present embodiment makes the ointment in Examples 1 to 3 in the same manner (conventional method that method is this field)
It is standby, then carry out replenishing water and preserving moisture experimental analysis, experimental method are as follows: 20-40 years old age women totally 60 people is chosen, is randomly divided into 3 groups,
Every group of 20 people.Experimenter uses to the ointment in Examples 1 to 3 respectively, using forehead as surveying when replenishing water and preserving moisture performance test
Position is tried, draws fixed area that size is 2 square centimeters as test zone, test method: 20 in the forehead of face
DEG C, in the indoor environment of relative humidity 50%, disappeared with CorneometerCM820 moisture of skin measuring instrument to every group of 20 women
The person's of expense forehead skin carries out the water content test of skin, the humidity measurements (Moisture that result passes through setting
Measurement Value, MMV) it indicates, final MMV value is indicated with the result averaged, to evaluate the benefit of the product
Water performance of keeping humidity, in which: MMV1 --- the skin MMV value before spread product, MMV2 --- the skin after spread product in 1 minute
MMV value, skin MMV value after MMV3 --- spread product 1 hour；Make-up water percentage=MMV2/MMV1 × 100%；Moisturizing rate=MMV3/
MMV2 × 100%, specific test result are as shown in table 1:
1 moisturizing of table, performance of keeping humidity test result
| Test sample | Make-up water percentage, % | Moisturizing rate, % |
| Embodiment 1 | 260 | 86 |
| Embodiment 2 | 245 | 75 |
| Embodiment 3 | 249 | 77 |
As it can be seen from table 1 there is ointment of the present invention preferable replenishing water and preserving moisture effect therefore can be very good to be applied to
Lip care, prevention or treatment chapped skin etc..
Embodiment 5
Itching-relieving action test
Experimental group 1~3 and control group 1~3 are set, take mouse 100, it is male female fifty-fifty, it is randomly divided into 5 groups, every group 20,
Mouse in experimental group 1~3 uses the ointment in Examples 1 to 3, and the mouse in control group 1 uses 50% physiological saline, control
Mouse in group 2 is in addition to without containing lithospermum euchromum Royle extract, other are identical as in embodiment 1, and the mouse in control group 3 removes
Outside without containing olea europaea fruit extract, other are same as Example 1.
Specific experiment process are as follows: first day by mouse it is right after instep unhairing, and uniformly abraded at the shaving of instep with coarse sandpaper
1cm2.It embrocates the product in experimental group 1~3 and control group 1~3 respectively at every group of mouse instep surface of a wound within second day, applies every time
Wiping amount is 0.5ml/, 3 times a day, is embrocated altogether 7 times.It is raw to mouse instep surface of a wound drop histamine phosphate after last embrocates 30min
Saline solution is managed, is then incremented by histamine phosphate normal saline solution concentration every 3min, concentration is respectively 0.01%,
0.02%, 0.03%, 0.04% is incremented by successively, and concentration increases by 0.01%, each dripping quantity 0.05ml every time, until mouse later licks
Until right metapedes.The total amount of computation organization's amine is itched valve as cause of the invention；Compared with control group 1, group difference point is carried out
Analysis, itching-relieving action test result are shown in Table 2.
Ointment in 2 experimental group 1~3 of table and control group 1~3 to histamine to mouse itch influence
Compared with control group 1: * is P < 0.05, and * * is P < 0.01
Studies have shown that histamine is a kind of important mediator that can cause pruitus.Mouse is in normal circumstances by anti-
After primary stimuli, skin lesion, pathology and immune etc. feature are consistent with mankind's dystopy skin lesion.It is above-mentioned the experimental results showed that, with sky
White control group 1 is compared, and ointment of the invention can all effectively inhibit pruitus caused by histamine phosphate, and antipruritic effect
Very well, compared with control group 2 and control group 3, the antipruritic effect of ointment is obviously good many in the embodiment of the present invention 1~3, wherein real
The effect applied in example 1 is best, this illustrates that there is collaboration to make for lithospermum euchromum Royle extract and olea europaea fruit extract in ointment of the present invention
With wherein when lithospermum euchromum Royle extract: when olea europaea fruit extract=3.5:2, synergy is best, and antipruritic effect is best.
Embodiment 6
Test is divided into control group and experimental group, and experimental group 1~3 is respectively prepared ointment in Examples 1 to 3, control group
It is divided into 14 groups, component contained in the ointment of control group 1~14 removes Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine
Berry extract, the weight ratio of four kinds of ingredients of Semen Myristicae extract are different outer, other are same as Example 1, and specific control group 1~
The weight ratio of Mosla chinensis extract, ampelopsis grossdentata leaf extract, four kinds of puncture vine berry extract, Semen Myristicae extract ingredients in 14
It is as shown in table 3:
Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Semen Myristicae extract in 3 control group of table
The content of four kinds of ingredients
In control group and experimental group, every group randomly selects 100 mouse and carries out using relevant skin care item, experimental group 1
The ointment that~3 subjects are prepared using Examples 1 to 3 respectively, the subjects of control group 1~14 use pair respectively
According to the ointment that group 1~14 is prepared, ointment application method and itching-relieving action test process are as in embodiment 5, if group
It knits amine cause and itches valve dosage as 80 μ g or more, be considered as effectively, statistics is efficient, and the results are shown in Table 4.
Skin care item in 4 experimental group of table and control group to histamine to mouse itch influence
As seen from Table 4, Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine fruit are contained only in control group 1~14
One or both of four kinds of extract, Semen Myristicae extract ingredients, three kinds do not have good antipruritic effect.And experimental group 1
With, containing there are four types of ingredient, there is good antipruritic effect in experimental group 3.Thus provable, in skin care item of the invention, Mosla chinensis
Four kinds of extract, ampelopsis grossdentata leaf extract, puncture vine berry extract, Semen Myristicae extract ingredients, which have, mutually promotes, mutually
The effect of collaboration can play significant inflammation-resisting itch-stopping effect.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (6)
1. a kind of multiple-effect ointment, which is characterized in that the ingredient comprising following parts by weight: 2~4 parts of deionized water, polysorbate-
60 0.7~0.9 part, 1.5~2 parts of sorbitan sesquioleate, 4.5~5.5 parts of zinc oxide, 3~4 parts of lithospermum euchromum Royle extract,
1.5~2.5 parts of olea europaea fruit extract, PhytosootheTM1.5~2.5 parts of 9766 phytosterol of LS, starch octenyl amber
2~4 parts of amber acid aluminium, 7~9 parts of antipruritic, wherein the antipruritic is Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture
The compounding of Chenopodiaceae berry extract, Semen Myristicae extract, the Mosla chinensis extract, ampelopsis grossdentata leaf extract, puncture vine fruit are extracted
The weight ratio of object, Semen Myristicae extract are as follows: Mosla chinensis extract: ampelopsis grossdentata leaf extract: puncture vine berry extract: nutmeg
Extract=1:2:1:1；The weight ratio of the lithospermum euchromum Royle extract and olea europaea fruit extract are as follows: lithospermum euchromum Royle extract:
Olea europaea fruit extract=3.5:2.
2. multiple-effect ointment as described in claim 1, which is characterized in that also include the saualane of 14~15 parts by weight.
3. multiple-effect ointment as described in claim 1, which is characterized in that also include the tocopherol acetate of 2~3 parts by weight.
4. multiple-effect ointment as described in claim 1, which is characterized in that also include the thickener of following parts by weight: microwax 34
~36 parts, 7~9 parts of atoleine, 5~7 parts of cera alba.
5. multiple-effect ointment as described in claim 1, which is characterized in that also include the three (behenyl of glycerol of 2.5~3.5 parts by weight
Acid/isostearic acid/dodecanedioic acid) ester.
6. multiple-effect ointment as described in claim 1, which is characterized in that the ingredient comprising following parts by weight: 3 parts of deionized water,
0.8 part of polysorbate -60,1.8 parts of sorbitan sesquioleate, 5 parts of zinc oxide, 3.5 parts of lithospermum euchromum Royle extract, oily olive
2 parts of olive berry extract, PhytosootheTM2 parts of 9766 phytosterol of LS, 8 parts of antipruritic, starch ocentyl succinic aluminium 3
Part, 14.4 parts of saualane, 2.5 parts of tocopherol acetate, wherein the antipruritic is Mosla chinensis extract, ampelopsis grossdentata leaf
The compounding of extract, puncture vine berry extract, Semen Myristicae extract.
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| CN201710990051.7A CN107753332B (en) | 2017-10-20 | 2017-10-20 | A kind of multiple-effect ointment |
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| CN107753332B true CN107753332B (en) | 2019-10-01 |
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| CN109055054A (en) * | 2018-10-11 | 2018-12-21 | 山东大学齐鲁医院 | A kind of mosquito-expelling and antipruritic handmade soap and preparation method thereof |
| CN109820973A (en) * | 2019-03-07 | 2019-05-31 | 江西鼎中科技有限公司 | A kind of nano-calcium carbonate magnesium ointment for treating onychomycosis |
| CN110236988B (en) * | 2019-07-08 | 2022-06-03 | 广州市中通生化制品有限公司 | Anti-allergy and soothing multiple-restoration composition, ointment thereof and preparation method |
| CN110478413A (en) * | 2019-09-26 | 2019-11-22 | 广州艾蓓生物科技有限公司 | Antipruritic stick of a kind of camellia oil reparation and preparation method thereof |
| CN114869827A (en) * | 2022-04-12 | 2022-08-09 | 贵州山茶产业综合开发有限公司 | Itching-relieving swelling-reducing moisturizing composition and preparation method and application thereof |
| CN115721586B (en) * | 2022-09-05 | 2023-09-15 | 广东丸美生物技术股份有限公司 | Skin care matrix |
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| CN105726416A (en) * | 2016-04-09 | 2016-07-06 | 福建省金鹿日化股份有限公司 | Gel with mosquito repelling, swelling subsiding and itching relieving functions |
| CN106265247B (en) * | 2016-08-23 | 2019-04-26 | 广州君研生物科技有限公司 | A kind of multiple-effect maintenance frost preparation method |
| CN107028845A (en) * | 2017-06-23 | 2017-08-11 | 湖北立天生物工程有限公司 | A kind of papaya cold cream and preparation method containing a variety of pure natural plant extracts |
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