CN107849111B - 在免疫显性腺病毒抗原表位中具有突变的溶瘤腺病毒及其在癌症治疗中的用途 - Google Patents

在免疫显性腺病毒抗原表位中具有突变的溶瘤腺病毒及其在癌症治疗中的用途 Download PDF

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CN107849111B
CN107849111B CN201680031591.6A CN201680031591A CN107849111B CN 107849111 B CN107849111 B CN 107849111B CN 201680031591 A CN201680031591 A CN 201680031591A CN 107849111 B CN107849111 B CN 107849111B
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adenovirus
epitope
tumor
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oncolytic adenovirus
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CN107849111A (zh
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莱蒙·阿莱马尼
拉鲁·吉尔
米里阿姆·巴赞
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CN201680031591.6A 2015-05-04 2016-05-04 在免疫显性腺病毒抗原表位中具有突变的溶瘤腺病毒及其在癌症治疗中的用途 Active CN107849111B (zh)

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US201562156748P 2015-05-04 2015-05-04
US62/156,748 2015-05-04
PCT/IB2016/052554 WO2016178167A1 (en) 2015-05-04 2016-05-04 Oncolytic adenoviruses with mutations in immunodominant adenovirus epitopes and their use in cancer treatment

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US20220354911A1 (en) * 2019-09-05 2022-11-10 Klinikum Rechts Der Isar Der Technischen Universität München Treatment of tumors by a combination of an oncolytic adenovirus, a cdk4/6 inhibitor and a further therapeutically active agent
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EP3292142B1 (en) 2024-03-20
AU2016257196B2 (en) 2021-11-25
CN107849111A (zh) 2018-03-27
CA2985029A1 (en) 2016-11-10
US11000560B2 (en) 2021-05-11
JP6740340B2 (ja) 2020-08-12
ES2987442T3 (es) 2024-11-14
WO2016178167A1 (en) 2016-11-10
AU2016257196A1 (en) 2017-11-30
JP2018519847A (ja) 2018-07-26
EP3292142A1 (en) 2018-03-14
US20180153946A1 (en) 2018-06-07

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