CN107831325A - Full-automatic chemiluminescence immunoassay analysis meter - Google Patents
Full-automatic chemiluminescence immunoassay analysis meter Download PDFInfo
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- CN107831325A CN107831325A CN201710983843.1A CN201710983843A CN107831325A CN 107831325 A CN107831325 A CN 107831325A CN 201710983843 A CN201710983843 A CN 201710983843A CN 107831325 A CN107831325 A CN 107831325A
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- liquid
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1011—Control of the position or alignment of the transfer device
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1067—Multiple transfer devices for transfer to or from containers having different spacing
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
A kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, including the support body of at least one workbench, control system, transport mechanism are provided with, and the station group being arranged at least one workbench；Station group includes functional station group, takes liquid station group and reaction cup storage area, and functional station group includes being incubated area, cleaning area and detection zone, takes liquid station group to include the pipette tips storage area that sample area, reagent area and storage have liquid-transfering gun pipette tips；The sample obtained from sample area and reagent area and reagent can be mixed and obtain determinand by transport mechanism in reaction cup under control of the control system, and determinand is sequentially delivered into incubation area, cleaning area and detection zone；Also include：Liquid feeding station unit, including at least two be used for will correspond at least one reaction cup from the liquid feeding position for taking the liquid obtained in liquid station group to add into reaction cup, each liquid feeding position.The invention provides the Full-automatic chemiluminescence immunoassay analysis meter that a kind of course of work is smooth, efficiency is higher.
Description
Technical field
The present invention relates to medical detection technology, and in particular to a kind of Full-automatic chemiluminescence immunoassay analysis meter.
Background technology
Full-automatic chemiluminescence immunoassay analysis meter is by detecting patients serum so as to the doctor to human body progress immunoassay
Learn testing instruments.Its groundwork process and operation principle are：By mechanical arm by quantitative patient serum sample and horseradish mistake
Oxide reagent, which is added to the solid-phase coating for being sent to liquid feeding position, to be had in the microwell plate of antibody；Then by conveyer by micropore
Plate is sent to incubation area and is incubated, and the testing molecule in area's serum is incubated can be with the conjugate and solid phase of horseradish peroxidase
Antibody specificity on carrier combines；Complete that microwell plate is sent into cleaning area separating, washing unreacted by conveyer after being incubated
Free composition, then add luminous bottom liquid, excite intermediate using the free energy of chemical reaction release, return to and excite from ground state
State, energy are discharged in the form of photon；Now, then microwell plate is transmitted in the analyzer of detection zone by conveyer and carried out
Detection, by the three-dimensional transmission system of instrument internal, read the number of photons in each hole by photon counter successively, it is to be measured in sample
The mathematical modeling that molecular concentration is established according to standard items carries out quantitative analysis；Finally, print data is reported, is examined with adjuvant clinical
It is disconnected.
A kind of existing Publication No. CN103267867B patent document discloses a kind of immune point of Full-automatic chemiluminescence
Analyzer, including support body and control system, be sequentially provided with from left to right on the support body sample area, lath feed system, incubate area,
Dilution vibration area and lath detecting system, the lath feed system include lath frame, enter panel assembly, plate taking device and be loaded slow
Flushing device, the sample-adding buffer unit include sample-adding buffering area base, the 3rd motor and the 3rd sliding equipment, on the lath frame
Lath by the first pusher arms be moved to it is described sample-adding buffering area base on, in the drive of the 3rd motor and the 3rd sliding equipment
Under it is for linear motion, and be loaded by sample arm.Full-automatic chemiluminescence immunoassay analysis meter disclosed in the patent document leads to
Cross and lath is moved on sample-adding buffering area base, the lath for then being pointed to be loaded on buffering area base by sample arm is carried out
Liquid feeding, and it is described sample-adding buffering area base by being moved in the presence of the 3rd motor and the 3rd sliding equipment, it can thus be appreciated that
Buffering area base is loaded as liquid feeding station, lath all on sample-adding buffering area base can only be waited, which all to add liquid, to be passed through
The lath for all adding liquid is all moved on to next station by the 3rd motor and the 3rd sliding equipment, adds the liquid feeding station
Stand-by period；During next station is moved to after all laths all add liquid, the sample arm also has to wait for it by institute
There is lath to be transferred to and return then to take the lath of non-liquid feeding after next station again, so as to which the circulation of work, increase could be completed
Stand-by period of the sample arm；The working method of such a Full-automatic chemiluminescence immunoassay analysis meter, add liquid feeding station
With the stand-by period of sample arm, make working cycles not smooth, and add time cost, make the reduction of its efficiency.
The content of the invention
Therefore, the technical problem to be solved in the present invention is to overcome automatic chemiluminescence immunoassay of the prior art
The defects of instrument course of work is not smooth, less efficient, so as to provide the full-automatic chemical that a kind of course of work is smooth, efficiency is higher
Luminescence immunoassay instrument.
Therefore, the technical solution adopted by the present invention is as follows：
A kind of Full-automatic chemiluminescence immunoassay analysis meter, including be provided with the support body of at least one workbench, control system,
Transport mechanism, and the station group being arranged at least one workbench；The station group includes functional station group, takes liquid work
Hyte and reaction cup storage area, the functional station group includes being incubated area, cleaning area and detection zone, described to take liquid station group to include
Sample area, reagent area and storage have the pipette tips storage area of liquid-transfering gun pipette tips；The transport mechanism can be in the control of the control system
The sample obtained from sample area and reagent area and reagent are mixed in reaction cup under system and obtain determinand, and by the determinand
It is sequentially delivered to incubation area, the cleaning area and the detection zone；
Also include：
Liquid feeding station unit, including at least two be used for from described the liquid obtained in liquid station group will be taken to add to described
Liquid feeding position in reaction cup, each liquid feeding position correspond at least one reaction cup.
The transport mechanism includes being used to transmit the pipetting device for taking the liquid in liquid station group, and for transmitting
State the shift mechanism of reaction cup.
Multiple blind holes for being used to house sample and/or reagent are formed in the reaction cup；
The pipetting device is arranged on support frame as described above, and including the first liquid relief structure for mobile example, and use
In the second liquid relief structure of mobile reagent；The first liquid relief structure includes multiple liquid relief arms for installing liquid-transfering gun.
The second liquid relief structure includes multiple liquid relief arms for installing liquid-transfering gun.
The liquid relief arm quantity that the first liquid relief structure and the second liquid relief structure include respectively and the reaction
Blind hole quantity on cup is consistent.
The shift mechanism includes：
Cup device is moved, including takes out reaction cup from the reaction cup storage area and is sent to the first of the liquid feeding position and move cup
Device, and take out the reaction cup from the liquid feeding position and be sent to the second of the functional station group and move cup device；
Liquid-adding device, consistent with the quantity of the liquid feeding position, the liquid-adding device can carry the reaction cup and in one
Individual position lock-out state forms the liquid feeding position；
Guiding mechanism, the movement of the shifting cup device can be at least oriented to.
The guiding mechanism includes the first guide rail and the second guide rail being oppositely arranged, and is arranged at first guide rail and institute
State the 3rd guide rail between the second guide rail；
The reaction cup storage area is arranged at side of first guide rail away from second guide rail, the incubation area,
Cleaning area and detection zone are arranged at the wherein side of second guide rail or are distributed in the both sides of second guide rail；
The first shifting cup device can reciprocatingly slide on first guide rail, and described second moves cup device can be described the
Reciprocatingly slided on two guide rails, the liquid-adding device is arranged on the 3rd guide rail and can back and forth slided on the 3rd guide rail
It is dynamic.
The reaction cup storage area includes the bearing of trend spread configuration along first guide rail and carries the reaction
First bearing groove of cup, the cup device that moves have the second bearing groove that can carry the reaction cup, and the liquid-adding device has
The 3rd bearing groove of the reaction cup can be carried；And first bearing groove, second bearing groove, the 3rd bearing groove point
It is not available for the reaction cup to extend along a length thereof direction to move back and forth.
The both ends of the reaction cup are respectively arranged with slot, and the shifting cup device includes：
First support, it is provided with second bearing groove；
Structure is delivered, can be reciprocally disposed in along the length bearing of trend of the reaction cup in the first support；
Stir structure, can in the vertical direction be reciprocally disposed in it is described delivery structure on, and with one plant
The first state of the reaction cup can be moved in the slot and along the length bearing of trend of the reaction cup, and one departs from
Second state of the slot.
Technical solution of the present invention, have the following advantages that：
1. a kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, including it is provided with least one workbench
Support body, control system, transport mechanism, and the station group being arranged at least one workbench；The station group includes work(
Energy station group, liquid station group and reaction cup storage area are taken, the functional station group includes being incubated area, cleaning area and detection zone, institute
State and take liquid station group to include the pipette tips storage area that sample area, reagent area and storage there are liquid-transfering gun pipette tips；The transport mechanism can be
The sample obtained from sample area and reagent area and reagent mixed in reaction cup under the control of the control system obtain it is to be measured
Thing, and the determinand is sequentially delivered to incubation area, the cleaning area and the detection zone；Also include：Liquid feeding station
Unit, including at least two be used for from described the liquid obtained in liquid station group will be taken to add to the liquid feeding in the reaction cup
Position, each liquid feeding position correspond at least one reaction cup.By setting at least two liquid feeding positions, in the transport mechanism
After sample or reagent are taken to the reaction cup completion liquid feeding of one of liquid feeding position, the transport mechanism can continue to sample
Product or reagent carry out liquid feeding to the reaction cup at another liquid feeding position, and the simultaneously ongoing transport mechanism can be complete by this
Reaction cup into liquid feeding is sent to the functional station group, and continues to take reaction cup to be sent to liquid feeding from reaction cup storage area
Position, operation above is repeated with this to complete the circulation of work, the pipetting device and the shifting machine can be made by thus planting setting
Structure is continuous to operationalize, it is not necessary to waits, greatly improves efficiency.
2. a kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, the transport mechanism includes being used to transmit institute
The pipetting device for taking the liquid in liquid station group is stated, and for transmitting the shift mechanism of the reaction cup.The pipetting device exists
Sample and reagent can be carried out taking liquid after taking pipette tips, are then injected into reaction cup and mixed, the shift mechanism energy
It is enough that the reaction cup equipped with sample and reagent mixture is sent in corresponding functional station group.
3. a kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, multiple be used for is formed in the reaction cup
The blind hole of accommodating sample and/or reagent；The pipetting device is arranged on support frame as described above, and including for mobile example
One liquid relief structure, and the second liquid relief structure for mobile reagent；The first liquid relief structure installs liquid-transfering gun including multiple
Liquid relief arm., can be simultaneously to the multiple blind holes of reaction cup by being to include multiple liquid relief arms by the first liquid relief structure setting
Sample-adding product are carried out, compared to a liquid relief arm is only provided with, such setting can save the time, improve efficiency.
4. a kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, the second liquid relief structure include it is multiple can
The liquid relief arm of liquid-transfering gun is installed.By being to include multiple liquid relief arms by the second liquid relief structure setting, it is possible to achieve described
Two liquid-transfering devices carry out reagent adding to the multiple blind holes of reaction cup simultaneously, save the time, improve efficiency.
5. a kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the invention, the first liquid relief structure and described second
The liquid relief arm quantity that liquid relief structure includes respectively is consistent with the blind hole quantity in the reaction cup.By such setting,
It can realize to the disposable whole liquid feedings of all blind holes for being set in the reaction cup, greatly increase efficiency.
Brief description of the drawings
, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical scheme of the prior art
The required accompanying drawing used is briefly described in embodiment or description of the prior art, it should be apparent that, in describing below
Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before creative work is not paid
Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the second work of the Full-automatic chemiluminescence immunoassay analysis meter provided in the first embodiment of the present invention
Platform and thereon station distribution schematic perspective view；；
Fig. 2 is after the Full-automatic chemiluminescence immunoassay analysis meter provided in the first embodiment of the present invention removes support body
Schematic perspective view；
Fig. 3 is the second workbench shown in Fig. 1 and the top view of station distribution thereon；
Fig. 4 be Fig. 2 shown in Full-automatic chemiluminescence immunoassay analysis meter the first workbench and thereon station distribution
Schematic perspective view；
Fig. 5 is the first workbench shown in Fig. 4 and the top view of station distribution thereon；
Fig. 6 is the shifting cup device of the Full-automatic chemiluminescence immunoassay analysis meter provided in the first embodiment of the present invention
Schematic perspective view
Description of reference numerals：
The workbench of 1- first；The workbench of 2- second；3- reaction cup storage areas；4- is incubated area；5- cleaning areas；6- detection zones；
7- sample areas；8- reagent areas；9- pipette tips storage areas；10- the first liquid relief structures；11- the second liquid relief structures；12- through holes；13- adds
Liquid level；14- first moves cup device；15- second moves cup device；16- liquid-adding devices；The guide rails of 17- first；The guide rails of 18- second；19-
3rd guide rail；The bearing grooves of 20- first；The bearing grooves of 21- second；The bearing grooves of 22- the 3rd；23- first supports；24- delivers structure；
25- stirs structure.
Embodiment
Technical scheme is clearly and completely described below in conjunction with accompanying drawing, it is clear that described implementation
Example is part of the embodiment of the present invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill
The every other embodiment that personnel are obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", " under ", "left", "right", " vertical ",
The orientation or position relationship of the instruction such as " level ", " interior ", " outer " be based on orientation shown in the drawings or position relationship, merely to
Be easy to the description present invention and simplify description, rather than instruction or imply signified device or element must have specific orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.In addition, term " first ", " second ",
" the 3rd " is only used for describing purpose, and it is not intended that instruction or hint relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected；Can
To be mechanical connection or electrical connection；Can be joined directly together, can also be indirectly connected by intermediary, Ke Yishi
The connection of two element internals.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this
Concrete meaning in invention.
As long as in addition, technical characteristic involved in invention described below different embodiments non-structure each other
It is be combined with each other into conflict can.
As Figure 1-Figure 5, a kind of Full-automatic chemiluminescence immunoassay analysis meter that the present embodiment provides, including it is provided with the
The support body of one workbench 1 and the second workbench 2, control system, transport mechanism, and be arranged at least one workbench
Station group；The station group includes functional station group, takes liquid station group and reaction cup storage area 3, and the functional station group includes
Area 4, cleaning area 5 and detection zone 6 are incubated, it is described to take liquid station group to have liquid-transfering gun pipette tips including sample area 7, reagent area 8 and storage
Pipette tips storage area 9；The transport mechanism will can obtain from sample area 7 and reagent area 8 under the control of the control system
Sample and reagent mix in reaction cup obtains determinand, and the determinand is sequentially delivered into the incubation area 4, described clear
Wash area 5 and the detection zone 6；Also include：Liquid feeding station unit, including at least two be used for will be taken from described take in liquid station group
The liquid obtained is added to the liquid feeding position 13 in the reaction cup, each corresponding at least one reaction cup in the liquid feeding position 13.
By setting at least two liquid feeding positions 13, sample or reagent are taken to the anti-of one of liquid feeding position 13 in the transport mechanism
After answering cup to complete liquid feeding, the transport mechanism can continue another reaction for taking sample or reagent to another liquid feeding position 13
Cup carries out liquid feeding, and the reaction cup of the completion liquid feeding can be sent to the function work by the simultaneously ongoing transport mechanism
Hyte is gone, and continues to take reaction cup to be sent to liquid feeding position 13 from reaction cup storage area 3, repeats operation above with this to complete work
Circulation, thus plant that setting can make the pipetting device and the shift mechanism is continuous operationalizes, it is not necessary to wait,
Greatly improve efficiency.
In the present embodiment, the sample area 7, reagent area 8 and pipette tips storage area 9 are located on first workbench 1, institute
State reaction cup storage area 3, incubation area 4, cleaning area 5, detection zone 6 and liquid feeding position 13 to be located on second workbench 2, described
Through hole 12 is offered with the corresponding position of liquid feeding position 13 on first workbench 1, is worked for the transport mechanism through described first
Platform 1 is loaded product or reagent in the liquid feeding position 13.
In the present embodiment, the transport mechanism includes being used to transmit the liquid relief machine for taking the liquid in liquid station group
Structure, and for transmitting the shift mechanism of the reaction cup.The pipetting device can enter after pipette tips are taken to sample and reagent
Row takes liquid, is then injected into reaction cup and is mixed, and the shift mechanism can will be anti-equipped with sample and reagent mixture
Cup is answered to be sent in corresponding functional station group.
Multiple blind holes for being used to house sample and/or reagent are formed in the reaction cup；The pipetting device is arranged at
On support frame as described above, and including the first liquid relief structure 10 for mobile example, and the second liquid relief structure for mobile reagent
11；The first liquid relief structure 10 includes multiple liquid relief arms for installing liquid-transfering gun.By the way that the first liquid relief structure 10 is set
It is set to including multiple liquid relief arms, sample-adding product can be carried out to the multiple blind holes of reaction cup simultaneously, compared to being only provided with a liquid relief
Arm, such setting can save the time, improve efficiency.
The second liquid relief structure 11 includes multiple liquid relief arms for installing liquid-transfering gun.By by the second liquid relief structure
11 are arranged to include multiple liquid relief arms, it is possible to achieve second liquid-transfering device is added an examination of to the multiple blind holes of reaction cup simultaneously
Agent, the time is saved, improve efficiency.
The liquid relief arm quantity that the first liquid relief structure 10 and the second liquid relief structure 11 include respectively with it is described
Blind hole quantity in reaction cup is consistent.Pass through such setting, it is possible to achieve to all blind holes set in the reaction cup
Disposable whole liquid feedings, greatly increase efficiency.
As shown in fig. 6, the shift mechanism includes：Cup device is moved, including reaction cup is taken out from the reaction cup storage area 3
And be sent to the first of the liquid feeding position 13 and move cup device 14, and take out the reaction cup from the liquid feeding position 13 and be sent to institute
State functional station group second moves cup device 15；Liquid-adding device 16, the liquid-adding device consistent with the quantity of the liquid feeding position 13
16 can carry the reaction cup and form the liquid feeding position 13 in a position lock-out state；Guiding mechanism, at least can be to institute
The movement for stating shifting cup device is oriented to.In the present embodiment, the shift mechanism is arranged on second workbench 2.Make
For disposable embodiment, the shift mechanism can also only include a shifting cup device, and pass through this shifting cup device
To complete to take out reaction cup from the reaction cup storage area 3 and be sent to the liquid feeding position 13, and taken out from the liquid feeding position 13
The reaction cup and the process for being sent to the functional station group.
The guiding mechanism includes the first guide rail 17 and the second guide rail 18 being oppositely arranged, and is arranged at first guide rail
The 3rd guide rail 19 between 17 and second guide rail 18；It is remote that the reaction cup storage area 3 is arranged at first guide rail 17
The side of second guide rail 18, the both sides for being incubated area 4, cleaning area 5 and detection zone 6 and being distributed in second guide rail 18；
The first shifting cup device 14 can reciprocatingly slide on first guide rail 17, and described second moves cup device 15 can be described second
Reciprocatingly slided on guide rail 18, the liquid-adding device 16 is arranged on the 3rd guide rail 19 and can be past on the 3rd guide rail 19
It is multiple to slide.In the present embodiment, the incubation area 4 is arranged at side of second guide rail 18 away from first guide rail 17,
The cleaning area 5 and detection zone 6 are arranged at second guide rail 18 close to the side of first guide rail 17.As disposable
Embodiment, incubation area 4, cleaning area 5 and the detection zone 6 can also be arranged to the same side of second guide rail 18.
Or, the guiding mechanism only includes a total guide rail, described as another disposable embodiment
First shifting cup device 14 and the second shifting cup device 15 are respectively arranged on total guide rail, and the reaction cup storage area 3 is set
Put and be arranged on institute in the wherein side of total guide rail, incubation area 4, cleaning area 5, detection zone 6 and the liquid-adding device 16
The opposite side of total guide rail is stated, the liquid-adding device 16 is fixedly installed on second workbench 2, and is deposited with the reaction cup
Area 3 is located at the homonymy of the guide rail, by first move cup device 14 on total guide rail motion come from the reaction cup storage area 3
Take out reaction cup and be sent to the liquid feeding position 13 and complete liquid feeding, and moved by the second shifting cup device 15 on total guide rail
To take out the reaction cup from the liquid feeding position 13 and be sent to incubation area 4, cleaning area 5 and the detection zone 6.
The reaction cup storage area 3 includes the bearing of trend spread configuration along first guide rail 17 and carried described
First bearing groove 20 of reaction cup, the cup device that moves have the second bearing groove 21 that can carry the reaction cup, the liquid feeding
Device 16 has the 3rd bearing groove 22 that can carry the reaction cup；And first bearing groove 20, second bearing groove 21,
3rd bearing groove 22 is available for the reaction cup to extend along a length thereof direction moving back and forth respectively.
The both ends of the reaction cup are respectively arranged with slot, and the shifting cup device includes：First support 23, is provided with
Second bearing groove 21；Structure 24 is delivered, can be reciprocally disposed in along the length bearing of trend of the reaction cup described
In first support 23；Stir structure 25, can in the vertical direction be reciprocally disposed in the delivery structure 24, and have
One is inserted in the slot and the first state of the reaction cup can be moved along the length bearing of trend of the reaction cup, and
One the second state for departing from the slot.
The course of work of the present embodiment under control system control is as follows：
It is in the course of work of the first workbench 1 and the above：The first liquid relief structure 10 is moved to pipette tips storage area 9 first,
Pipette tips corresponding to liquid relief arm alignment thereon are simultaneously moved down, and pipette tips are arranged on liquid relief arm, are then provided with the shifting of pipette tips
Liquid arm moves to pipette tips storage area 9 after certain altitude straight up, and the first liquid relief structure 10 then moves to sample
The sample of the sample area 7 is drawn into the pipette tips of the first liquid relief structure 10 by product area 7 by liquid relief arm thereon；Carry out simultaneously
The second liquid relief structure 11 be moved to pipette tips storage area 9, by liquid relief arm thereon by pipette tips be arranged on its liquid relief arm on, then
The second liquid relief structure 11 then moves to reagent area 8 and is drawn into the reagent of the reagent area 8 by liquid relief arm thereon
In the pipette tips of second liquid relief structure 11；Then the first liquid relief structure 10, the second liquid relief structure 11 are moved respectively to described logical
At hole 12, liquid relief arm thereon is moved down through the through hole 12, respectively by sample and reagent injector to being located at liquid feeding position
In 13 reaction cup.Then operation is added to the reaction positioned at another liquid feeding position 13 followed by by sample and reagent more than repeating
In cup.It should be noted that after first liquid-transfering device completes liquid feeding to the reaction cup of first liquid feeding position 13, may proceed to
To take arms head and sample continues to carry out liquid feeding to the reaction cup of another liquid feeding position 13, second liquid-transfering device is same, and
The reaction cup of the ongoing completion liquid feeding for being located at first liquid feeding position 13 can be transported to function work by shift mechanism simultaneously
Hyte, then proceed to take next reaction cup to be conveyed to first liquid feeding position 13, and the reaction cup of another liquid feeding position 13
Motion process it is same, the circulation of work is completed with this, it is not necessary to first liquid-transfering device and second liquid relief
The wait of device, efficiency is improved with this.
The course of work on the second workbench 2 is as follows：First first shifting cup device 14 moves along first guide rail 17,
Make the notch of the notch of the second bearing groove 21 thereon and the first bearing groove 20 of the reaction cup storage area 3 relative, Ran Houwei
Notch and the described first carrying of second bearing groove 21 are moved in the delivery structure 24 on the described first shifting cup device 14
The notch of groove 20 is relative to be located, and then the structure 25 of stirring in the delivery structure 24 move be inserted into instead straight down
The slot of close described one end of second bearing groove 21 of cup is answered, then the delivery structure 24 is to close to second bearing groove 21
Direction movement, make it drive the reaction cup to be slided along the bearing groove 21 of the first bearing groove 20 and second, make the reaction cup move
Move onto the second bearing groove 21, then the structure 25 of stirring is moved straight up, disengages it from an end slot of the reaction cup,
Then the delivery structure 24 makes it stir knot to the other end for moving to reaction cup close to the direction of first bearing groove 20
Structure 25 moves the slot for the other end for being inserted into the reaction cup straight down, and described first moves cup device 14 along first guide rail
17 movements, make the second bearing groove 21 thereon relative with the notch of the 3rd bearing groove 22 on liquid-adding device one of them described 16,
Then the delivery structure 24 is moved to the direction close to the 3rd bearing groove 22, the structure 25 of stirring is driven the reaction
Cup is moved on second bearing groove 21 and the 3rd bearing groove 22, and the reaction cup is moved into the 3rd bearing groove 22
On, then it is described stir structure 25 and move straight up disengage it from the reaction cup, now the reaction cup is located at the liquid-adding device
On 16 the 3rd bearing groove 22, then the liquid-adding device 16 moves along the 3rd guide rail 19 makes it drive the reaction cup to be moved to
Corresponding liquid feeding position 13, (first invention addition：Then erected by the bearing structure on first liquid-adding device 16
The straight close through hole 12 of motion upwards, makes the rim of a cup of the reaction cup and the pipette tips to the reaction cup liquid feeding close) described first
Liquid relief structure 10, the second liquid relief structure 11 stretch into successively from the through hole 12 to be pointed to the reaction cup of liquid feeding position 13 and is added
Sample and reagent, the reaction cup for adding sample and reagent follow the liquid-adding device 16 to be moved along the 3rd guide rail 19 to described second
Cup device 15 moves, and then reaction cup that this is added to sample and reagent by mode same above is moved to second shifting
On cup device 15, then reaction cup that this is added to sample and reagent by the described second shifting cup device 15 is sent to described incubate successively
Educate in area 4, cleaning area 5 and detection zone 6.It should be noted that after the reaction cup of first liquid feeding position 13 completes liquid feeding, can be right
The reaction cup of second liquid feeding position 13 carries out liquid feeding, and while liquid feeding is carried out to second reaction cup, first liquid feeding position
13 reaction cup can be transported in the incubation area 4, cleaning area 5 and detection zone 6 by the described second shifting cup device 15, and by described
First shifting cup device 14 continues to take reaction cup to be transported on first liquid feeding position 13 from the reaction cup storage area 3, is completed with this
The working cycles of first liquid feeding position 13, the working cycles of other liquid feeding positions 13 are same, it can be seen that multiple by setting
Liquid-adding device 16 and liquid feeding position 13, described first can be made to move cup device 14 and described second and move 15 continuous running of cup device
Get up, reached with this and put forward efficient purpose.
Obviously, above-described embodiment is only intended to clearly illustrate example, and is not the restriction to embodiment.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of change or
Change.There is no necessity and possibility to exhaust all the enbodiments.And the obvious change thus extended out or
Among changing still in the protection domain of the invention.
Claims (9)
- A kind of 1. Full-automatic chemiluminescence immunoassay analysis meter, it is characterised in that including be provided with least one workbench support body, Control system, transport mechanism, and the station group being arranged at least one workbench；The station group includes functional station Group, liquid station group and reaction cup storage area (3) are taken, the functional station group includes being incubated area (4), cleaning area (5) and detection zone (6) it is, described to take liquid station group to include sample area (7), reagent area (8) and deposit the pipette tips storage area (9) for having liquid-transfering gun pipette tips；Institute The sample and reagent that stating transport mechanism will can obtain under the control of the control system from sample area (7) and reagent area (8) exist In reaction cup mixing obtain determinand, and by the determinand be sequentially delivered to it is described incubation area (4), the cleaning area (5) and The detection zone (6)；Also include：Liquid feeding station unit, including at least two be used for from described the liquid obtained in liquid station group will be taken to add to the reaction Liquid feeding position (13) in cup, each corresponding at least one reaction cup of the liquid feeding position (13).
- 2. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, it is characterised in that the transport mechanism includes For transmitting the pipetting device for taking the liquid in liquid station group, and for transmitting the shift mechanism of the reaction cup.
- 3. Full-automatic chemiluminescence immunoassay analysis meter according to claim 2, it is characterised in thatMultiple blind holes for being used to house sample and/or reagent are formed in the reaction cup；The pipetting device is arranged on support frame as described above, and including the first liquid relief structure (10) for mobile example, and use In the second liquid relief structure (11) of mobile reagent；The first liquid relief structure (10) includes multiple liquid reliefs for installing liquid-transfering gun Arm.
- 4. Full-automatic chemiluminescence immunoassay analysis meter according to claim 3, it is characterised in that the second liquid relief structure (11) multiple liquid relief arms for installing liquid-transfering gun are included.
- 5. Full-automatic chemiluminescence immunoassay analysis meter according to claim 4, it is characterised in that the first liquid relief structure And the liquid relief arm quantity that includes respectively of the second liquid relief structure (11) and the blind hole quantity one in the reaction cup (10) Cause.
- 6. according to the Full-automatic chemiluminescence immunoassay analysis meter any one of claim 2-5, it is characterised in that the shifting Position mechanism includes：Cup device is moved, including takes out reaction cup from the reaction cup storage area (3) and is sent to the first of the liquid feeding position (13) Cup device (14) is moved, and takes out the reaction cup from the liquid feeding position (13) and is sent to the second of the functional station group and move cup Device (15)；Liquid-adding device (16), consistent with the quantity of the liquid feeding position (13), the liquid-adding device (16) can carry the reaction cup And form the liquid feeding position (13) in a position lock-out state；Guiding mechanism, the movement of the shifting cup device can be at least oriented to.
- 7. Full-automatic chemiluminescence immunoassay analysis meter according to claim 6, it is characterised in that the guiding mechanism includes The first guide rail (17) and the second guide rail (18) being oppositely arranged, and it is arranged at first guide rail (17) and second guide rail (18) the 3rd guide rail (19) between；The reaction cup storage area (3) is arranged at side of first guide rail (17) away from second guide rail (18), described Area (4) are incubated, cleaning area (5) and detection zone (6) are arranged at the wherein side of second guide rail (18) or are distributed in described the The both sides of two guide rails (18)；The first shifting cup device (14) can reciprocatingly slide on first guide rail (17), and described second moves cup device (15) can Reciprocatingly slided on second guide rail (18), the liquid-adding device (16) is arranged on the 3rd guide rail (19) and can be in institute State and reciprocatingly slided on the 3rd guide rail (19).
- 8. Full-automatic chemiluminescence immunoassay analysis meter according to claim 7, it is characterised in that the reaction cup storage area (3) include the bearing of trend spread configuration along first guide rail (17) and carry the first bearing groove of the reaction cup (20), the cup device that moves has the second bearing groove (21) that can carry the reaction cup, and the liquid-adding device (16) has can Carry the 3rd bearing groove (22) of the reaction cup；And first bearing groove (20), second bearing groove (21), described Three bearing grooves (22) are available for the reaction cup to extend along a length thereof direction moving back and forth respectively.
- 9. Full-automatic chemiluminescence immunoassay analysis meter according to claim 8, it is characterised in that the both ends of the reaction cup Slot is respectively arranged with, the shifting cup device includes：First support (23), it is provided with second bearing groove (21)；Structure (24) is delivered, the first support (23) can be reciprocally disposed in along the length bearing of trend of the reaction cup On；Stir structure (25), can in the vertical direction be reciprocally disposed on delivery structure (24), and with one It is inserted in the slot and the first state of the reaction cup can be moved along the length bearing of trend of the reaction cup, and one Depart from the second state of the slot.
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| CN201710983843.1A CN107831325B (en) | 2017-10-20 | 2017-10-20 | Full-automatic chemiluminescence immunoassay analyzer |
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| CN201710983843.1A CN107831325B (en) | 2017-10-20 | 2017-10-20 | Full-automatic chemiluminescence immunoassay analyzer |
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| CN107831325B CN107831325B (en) | 2021-02-26 |
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| CN109709347A (en) * | 2018-12-26 | 2019-05-03 | 迪瑞医疗科技股份有限公司 | A kind of incubation system and its incubation method |
| CN109916817A (en) * | 2018-06-14 | 2019-06-21 | 德诺杰亿（北京）生物科技有限公司 | A kind of liquid relief and analytical equipment |
| CN110531069A (en) * | 2019-08-09 | 2019-12-03 | 厦门市波生生物技术有限公司 | A kind of multinomial combined immunization fluorescence tomography detection system of slitting |
| CN110823871A (en) * | 2018-08-14 | 2020-02-21 | 深圳市新产业生物医学工程股份有限公司 | Luminescence analyzer and analysis method thereof |
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| CN112881740A (en) * | 2019-11-29 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Sample adding assembly, sample analyzer and sample adding method |
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| CN112881740A (en) * | 2019-11-29 | 2021-06-01 | 深圳市帝迈生物技术有限公司 | Sample adding assembly, sample analyzer and sample adding method |
| CN114152496A (en) * | 2021-12-31 | 2022-03-08 | 河南赛诺特生物技术有限公司 | Automatic immunohistochemical dyeing machine |
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