CN206638610U - Multi-needle magnetic particle chemiluminescence immunoassay analyzer test solution suction device - Google Patents

Multi-needle magnetic particle chemiluminescence immunoassay analyzer test solution suction device Download PDF

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Publication number
CN206638610U
CN206638610U CN201720260916.XU CN201720260916U CN206638610U CN 206638610 U CN206638610 U CN 206638610U CN 201720260916 U CN201720260916 U CN 201720260916U CN 206638610 U CN206638610 U CN 206638610U
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needle
sliding block
belt
test solution
aspirating needle
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CN201720260916.XU
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胡晓雷
胡亚林
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Chongqing Keysmile Biotechnology Co ltd
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Chongqing Keysmile Biotechnology Co ltd
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Abstract

The utility model discloses a multi-needle magnetic particle chemiluminescence immunoassay analyzer test solution suction device, which comprises a bottom plate, wherein a cup strip moving seat and at least two sets of liquid suction components are arranged on the bottom plate, each liquid suction component comprises a liquid suction needle transfer mechanism, a liquid suction needle is arranged on each liquid suction needle transfer mechanism, reaction cup strips are arranged on the cup strip moving seat corresponding to the liquid suction needles, the liquid suction needle transfer mechanisms drive the liquid suction needles to pass in and out the reaction cup strips, a plurality of reaction cup strips can be simultaneously placed on the cup strip moving seat, one or more reaction cup strips can be used for processing reagent addition in a normal process, other reaction cup strips can be used for processing the conditions of two-step method and the like needing queue insertion or reagent addition in reverse, the liquid suction needles of the components can respectively suck different reactants, then the liquid suction needles are transferred to the positions above the reaction cup strips through the liquid suction needle transfer mechanisms and then the reactants are added into the corresponding reaction cup strips, the detection efficiency is greatly improved.

Description

Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means
Technical field
It the utility model is related to medical instruments field, and in particular to a kind of Multi needle magnetic microparticle chemiluminescence immune assay instrument Test solution suction means.
Background technology
Full-automatic chemiluminescence immunoassay analysis meter is by detecting patients serum so as to the doctor to human body progress immunoassay Learn testing instruments.Quantitative patients serum and horseradish peroxidase (HRP) are added into solid-phase coating the white impermeable of antibody In bright microwell plate, the testing molecule in serum and the antibody specificity knot on the conjugate and solid phase carrier of horseradish peroxidase Close, the unreacted free composition of separating, washing;Then, luminous bottom liquid is added, in being excited using the free energy of chemical reaction release Mesosome, excitation state is returned to from ground state, energy is discharged in the form of photon;Now, microwell plate is inserted in analyzer, passes through instrument Internal three-dimensional transmission system, the number of photons in each hole, and the mathematical modulo established according to standard items are read by photon counter successively Type carries out quantitative analysis, just can draw detection and analysis result.Due to full-automatic detection analysis instrument can be automatically performed from sample-adding, plus The series of operation steps such as reagent, incubation reaction, cleaning, detection, therefore detected sample is determined using full-automatic detection analysis instrument Content of certain composition has become very universal in this.Before being detected to serum, it is necessary to undergo filling reagent, incubation, Washing plus the process such as substrate and mixing, single detection time is longer, and the detection efficiency of luminescence immunoassay instrument is relatively low.
Utility model content
To solve above technical problem, the utility model provides a kind of Multi needle magnetic microparticle chemiluminescence immune assay instrument examination Liquid suction means.
Technical scheme is as follows:A kind of Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means, its key exist In:Including bottom plate, the bottom plate is provided with cup bar Mobile base and at least two sets of imbibition components, and the imbibition component moves including aspirating needle Mechanism is sent, aspirating needle is installed on the aspirating needle transfer mechanism, the aspirating needle is corresponded on the cup bar Mobile base and is provided with reaction Cup bar, the aspirating needle transfer mechanism drives the aspirating needle to pass in and out the reaction cup bar, so as to draw in the reaction cup bar Liquid or to the reaction cup bar adding liquid.
Different reactants can be drawn respectively using the aspirating needle of the multiple imbibition components of above-mentioned technical proposal, then pass through suction Reactant is added in corresponding reaction cup bar by liquid pin transfer mechanism again after aspirating needle is transplanted on above reaction cup bar, multiple Syringe needle operates the speed that can effectively lift addition reagent simultaneously, and multiple syringe needles can also be operated individually in addition, be suitable for multiple Project operates simultaneously, greatly improves detection efficiency.
Further, above-mentioned cup bar Mobile base is arranged on x in linear slide mechanism, and the cup bar Mobile base is provided with least Two cup bar mounting grooves, the reaction cup bar are placed in the cup bar mounting groove, and the aspirating needle transfer mechanism includes y to straight To linear slide mechanism, the y is provided with z to linear slide mechanism to linear slide mechanism by line sliding equipment and z, the z to Linear slide mechanism is provided with the aspirating needle, and the x is to linear slide mechanism below all aspirating needles.Using Multiple reaction cup bars can be placed simultaneously on this programme cup bar Mobile base, and wherein one or several reaction cup bar can be used for processing normal Reagent addition under flow, other reaction cup bar can be used for the needs such as processing two-step method to jump the queue, repeat addition reagent or again The situation of reagent is added, can further improve detection efficiency.
A row is respectively equipped with bottom plate corresponding to each aspirating needle and inhales sample hole, often arrange the suction sample hole respectively along corresponding The aspirating needle y to motion track be distributed.It is can be placed in using this design sample liquid containing cup below bottom plate, by y to straight During line sliding equipment movement aspirating needle, aspirating needle may pass through suction sample hole and sample liquid be drawn into aspirating needle, then by sample Liquid is injected into reaction cup bar.
Corresponding each aspirating needle, which is respectively equipped with, on above-mentioned bottom plate washes needle device, and the needle device of washing is located at corresponding institute The y of aspirating needle is stated to below motion track.Aspirating needle can be cleaned by washing needle device after being drawn using this scheme sample liquid Totally in case next time uses.
The first slide rail and the first sliding block that above-mentioned x includes cooperating to linear slide mechanism, first slide rail are set On the bottom plate, the cup bar Mobile base is fixedly mounted on first sliding block, and first sliding block is connected with x to slip Drive device;
Two the first belt pulleys that the x includes being arranged on the bottom plate to sliding driving device, two described first The belt of same root first is arranged with belt pulley, first belt is provided with the first synchronization blocks, first sliding block and described the One synchronization blocks connect, and any one described first belt pulley is connected with the first motor.
First pulley rotation is driven by the first motor using such scheme, so that the connection of the first belt is thereon Synchronization blocks rotate simultaneously, so as to realize the movement to cup bar Mobile base.
The second slide rail and the second sliding block that above-mentioned y includes cooperating to linear slide mechanism, the second sliding block connection There is y to sliding driving device;
The y includes two the second belt pulleys to sliding driving device, and the bottom plate is provided with sliding rail rack, and described second Slide rail is fixedly mounted on the sliding rail rack, and two second belt pulleys are fixedly mounted on the sliding rail rack, two The belt of same root second is arranged with second belt pulley, second belt is provided with the second synchronization blocks, second sliding block It is connected with second synchronization blocks, any one described second belt pulley is connected with the second motor.Using the letter of this design structure List, cost are low, and frictional dissipation is small.
The 3rd slide rail and the 3rd sliding block that above-mentioned z includes cooperating to linear slide mechanism, the 3rd slide rail are fixed On second sliding block, the 3rd sliding block is provided with the aspirating needle, and the 3rd sliding block is connected with z and driven to slip Dynamic device;
The z includes the 3rd motor and two the 3rd belt pulleys, two the 3rd belts to sliding driving device Wheel is set along the glide direction of the 3rd sliding block respectively, and the belt of same root the 3rd is arranged with two the 3rd belt pulleys, 3rd belt is provided with the 3rd synchronization blocks, and the 3rd sliding block is connected with the 3rd synchronization blocks, any one described 3rd skin Belt wheel is connected with the 3rd motor.Using this design structure is simple, cost is low, frictional dissipation is small.
Above-mentioned 3rd sliding block is provided with shank installing plate, and the shank installing plate is provided with z to shank neck, the aspirating needle Shank along z to being fastened on the z into shank neck.Directly sticked into shank neck i.e. during using this design and installation aspirating needle Can, simplicity quick for installation.
The top cuff of above-mentioned aspirating needle has fixed cover, and the fixed cover is fastened on the z into shank neck, the fixation The z of set lower section is provided with supporting plate into shank neck, and the supporting plate holds the fixed cover.Using this design washing lotion pin clamping Firmly, it is not easy to skid off out of shank neck.
Above-mentioned shank installing plate is provided with fixed cover baffle plate, the fixed cover baffle plate be covered in z where the fixed cover to On the notch of shank neck.Fixed cover is blocked using this scheme fixed cover baffle plate, prevents aspirating needle from deviating from from shank neck.
Beneficial effect:It is that can place multiple reaction cups on glass bar Mobile base simultaneously using the beneficial effects of the utility model The reagent addition that bar, wherein one or several reaction cup bar can be used under processing normal flow, reaction cup bar in addition can be used for The processing needs such as two-step method are jumped the queue or added in turn the situation of reagent, and the aspirating needle of multiple imbibition components can draw difference respectively Reactant, reactant is added to pair again after then aspirating needle is transplanted on above reaction cup bar by aspirating needle transfer mechanism In the reaction cup bar answered, detection efficiency is greatly improved.
Brief description of the drawings
Fig. 1 is dimensional structure diagram of the present utility model;
Fig. 2 is y to linear slide mechanism and z to the dimensional structure diagram of linear slide mechanism;
Fig. 3 is the enlarged drawing in a portions in Fig. 2.
Embodiment
With reference to embodiment and accompanying drawing, the utility model is described in further detail.
As Figure 1-3, a kind of Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means, including bottom plate 1, The bottom plate 1 is provided with cup bar Mobile base 6 and at least two sets of imbibition components 13, and the imbibition component includes aspirating needle transfer mechanism, Aspirating needle 132 is installed on the aspirating needle transfer mechanism, the aspirating needle 132 is corresponded on the cup bar Mobile base 6 and is provided with reaction Cup bar, the aspirating needle transfer mechanism drives the aspirating needle 132 to pass in and out the reaction cup bar, so as to draw the reaction cup Liquid in bar or to the reaction cup bar adding liquid.
The cup bar Mobile base 6 is arranged on x in linear slide mechanism, and the cup bar Mobile base 6 is provided with least two Cup bar mounting groove, the reaction cup bar are placed in the cup bar mounting groove, and the aspirating needle transfer mechanism includes y and slided to straight line Motivation structure 2 and z are to linear slide mechanism 3, and the x is to, y to being mutually perpendicular to, the y is provided with to linear slide mechanism 2 with z For z to linear slide mechanism 3, the z is provided with the aspirating needle 132 to linear slide mechanism 3, and the x is to linear slide mechanism Positioned at all lower sections of aspirating needle 132, it is respectively equipped with a row on bottom plate 1 corresponding to each aspirating needle 132 and inhales sample hole 10, often arrange the suction sample hole 10 and be distributed respectively along the y of the corresponding aspirating needle 132 to motion track, it is right on the bottom plate 1 Answer each aspirating needle 132 to be respectively equipped with and wash needle device 11, the needle device 11 of washing is located at the corresponding aspirating needle 132 Y includes washing pin cup to motion track lower section, the needle device 11 of washing, and this is washed pin cup inwall and is provided with wash water shower nozzle.
The first slide rail 4 and the first sliding block 5 that the x includes cooperating to linear slide mechanism, first slide rail 4 are set Put on the bottom plate 1, the cup bar Mobile base 6 is fixedly mounted on first sliding block 5, and first sliding block 5 is connected with x To sliding driving device;
The x includes being arranged on two the first belt pulleys 7 on the bottom plate 1 to sliding driving device, two described the The first belt of same root 8 is arranged with one belt pulley 7, first belt 8 is provided with the first synchronization blocks, first sliding block 5 with The first synchronization blocks connection, any one described first belt pulley 7 are connected with the first motor 9, first motor 9 It is fixedly mounted on the lower surface of the bottom plate 1.
The second slide rail 201 and the second sliding block 202 that the y includes cooperating to linear slide mechanism 2, described second slides Block 202 is connected with y to sliding driving device;
The y includes two the second belt pulleys 203 to sliding driving device, and the bottom plate 1 is provided with sliding rail rack 205, Second slide rail 201 is fixedly mounted on the sliding rail rack 205, and two second belt pulleys 203 are fixedly mounted on institute State on sliding rail rack 205, be arranged with the second belt of same root 206 on two second belt pulleys 203, second belt 206 The second synchronization blocks are provided with, second sliding block 202 is connected with second synchronization blocks, any one described second belt pulley 203 The second motor 204 is connected with, second motor 204 is fixedly mounted on the upper of the sliding rail rack 205.
The 3rd slide rail 301 and the 3rd sliding block 302 that the z includes cooperating to linear slide mechanism 3, the described 3rd slides Rail 301 is fixedly mounted on second sliding block 202, and the 3rd sliding block 302 is provided with the aspirating needle 132, and the described 3rd Sliding block 302 is connected with z to sliding driving device;
The z includes the 3rd motor 305 and two the 3rd belt pulleys 303 to sliding driving device, two described Three belt pulleys 303 are set along the glide direction of the 3rd sliding block 302 respectively, are arranged with two the 3rd belt pulleys 303 The belt 304 of same root the 3rd, the 3rd belt 304 are provided with the 3rd synchronization blocks, and the 3rd sliding block 302 is synchronous with the described 3rd Block is connected, and any one described 3rd belt pulley 303 is connected with the 3rd motor 305, the upper end of the 3rd slide rail 301 Provided with roller installing plate 307, one of them described 3rd belt pulley 303 is fixedly mounted on the roller installing plate 307, another Individual 3rd belt pulley 303 is fixedly mounted on second sliding block 202, and the 3rd motor 305 is fixedly mounted on On 3rd slide rail 301, the 3rd slide rail 301 between two the 3rd belt pulleys 303 is provided with tensioning wheel 306, 3rd belt 304 is sleeved on the tensioning wheel 306.
3rd sliding block 302 is provided with shank installing plate 131, and the shank installing plate 131 is provided with z to shank neck 133, along z to the z is fastened on into shank neck 133, the top of the aspirating needle 132 covers the shank of the aspirating needle 132 Hoop has fixed cover 134, and the fixed cover 134 is fastened on the z into shank neck 133, the z of the lower section of fixed cover 134 Supporting plate is provided with into shank neck 133, the supporting plate holds the fixed cover 134, and the shank installing plate 131 is provided with solid Surely baffle plate 135 is covered, the fixed cover baffle plate 135 is covered in the z where the fixed cover 134 on the notch of shank neck 133.
The bottom plate 1 is provided with multiple first sensors 12, and multiple first sensors 12 are along the x to linear slide The glide direction of mechanism is set gradually, and the roller installing plate 307 is provided with second sensor 308, and the second sensor 308 is used In detecting whether the imbibition component resets in place, the sliding rail rack 205 is provided with multiple 3rd sensors 207, Duo Gesuo Glide direction of the 3rd sensor 207 along the y to straight line interdynamic mechanism is stated to set gradually.
Finally it should be noted that foregoing description is only preferred embodiment of the present utility model, the common skill of this area Art personnel on the premise of without prejudice to the utility model aims and claim, can make under enlightenment of the present utility model Expression, such conversion are each fallen within the scope of protection of the utility model as multiple types.

Claims (10)

  1. A kind of 1. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means, it is characterised in that:Including bottom plate (1), The bottom plate (1) is provided with cup bar Mobile base (6) and at least two sets of imbibition components (13), and the imbibition component is transferred including aspirating needle Mechanism, aspirating needle (132) is installed on the aspirating needle transfer mechanism, the aspirating needle is corresponded on the cup bar Mobile base (6) (132) reaction cup bar is provided with, the aspirating needle transfer mechanism drives the aspirating needle (132) to pass in and out the reaction cup bar, so as to Draw liquid in the reaction cup bar or to the reaction cup bar adding liquid.
  2. 2. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 1, its feature exist In:The cup bar Mobile base (6) is arranged on x in linear slide mechanism, and the cup bar Mobile base (6) is provided with least two glasss Bar mounting groove, the reaction cup bar are placed in the cup bar mounting groove, and the aspirating needle transfer mechanism includes y to linear slide Mechanism (2) and z are provided with z to linear slide mechanism (3), institute to linear slide mechanism (3), the y to linear slide mechanism (2) State z and be provided with the aspirating needle (132) to linear slide mechanism (3), the x is located at all imbibitions to linear slide mechanism Below pin (132).
  3. 3. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 2, its feature exist In:A row is respectively equipped with bottom plate (1) corresponding to each aspirating needle (132) and inhales sample hole (10), often arrange the suction sample hole (10) it is distributed respectively along the y of the corresponding aspirating needle (132) to motion track.
  4. 4. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 3, its feature exist In:Corresponding each aspirating needle (132), which is respectively equipped with, on the bottom plate (1) washes needle device (11), described to wash needle device (11) Y positioned at the corresponding aspirating needle (132) is to below motion track.
  5. 5. the Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 2,3 or 4, it is special Sign is:The first slide rail (4) and the first sliding block (5) that the x includes cooperating to linear slide mechanism, first slide rail (4) it is arranged on the bottom plate (1), the cup bar Mobile base (6) is fixedly mounted on first sliding block (5), and described first Sliding block (5) is connected with x to sliding driving device;
    The x includes being arranged on two the first belt pulleys (7) on the bottom plate (1) to sliding driving device, two described the The belt of same root first (8) is arranged with one belt pulley (7), first belt (8) is provided with the first synchronization blocks, and described first slides Block (5) is connected with first synchronization blocks, and any one described first belt pulley (7) is connected with the first motor (9).
  6. 6. the Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 2,3 or 4, it is special Sign is:The second slide rail (201) and the second sliding block (202) that the y includes cooperating to linear slide mechanism (2), it is described Second sliding block (202) is connected with y to sliding driving device;
    The y includes two the second belt pulleys (203) to sliding driving device, and the bottom plate (1) is provided with sliding rail rack (205), second slide rail (201) is fixedly mounted on the sliding rail rack (205), two second belt pulleys (203) It is fixedly mounted on the sliding rail rack (205), the belt of same root second is arranged with two second belt pulleys (203) (206), second belt (206) is provided with the second synchronization blocks, and second sliding block (202) is connected with second synchronization blocks, Any one described second belt pulley (203) is connected with the second motor (204).
  7. 7. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 6, its feature exist In:The 3rd slide rail (301) and the 3rd sliding block (302) that the z includes cooperating to linear slide mechanism (3), the described 3rd Slide rail (301) is fixedly mounted on second sliding block (202), and the 3rd sliding block (302) is provided with the aspirating needle (132), the 3rd sliding block (302) is connected with z to sliding driving device;
    The z includes the 3rd motor (305) and two the 3rd belt pulleys (303) to sliding driving device, two described Three belt pulleys (303) are set along the glide direction of the 3rd sliding block (302) respectively, on two the 3rd belt pulleys (303) Be arranged with the belt (304) of same root the 3rd, the 3rd belt (304) is provided with the 3rd synchronization blocks, the 3rd sliding block (302) with The 3rd synchronization blocks connection, any one described 3rd belt pulley (303) are connected with the 3rd motor (305).
  8. 8. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 7, its feature exist In:3rd sliding block (302) is provided with shank installing plate (131), and the shank installing plate (131) is provided with z to shank neck (133), the shank of the aspirating needle (132) is interior to shank neck (133) along z to the z is fastened on.
  9. 9. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 8, its feature exist In:The top cuff of the aspirating needle (132) has fixed cover (134), and the fixed cover (134) is fastened on the z to shank neck (133) in, the z below the fixed cover (134) is provided with supporting plate into shank neck (133), and the supporting plate is by the fixation Set (134) is held.
  10. 10. Multi needle magnetic microparticle chemiluminescence immune assay instrument test solution suction means according to claim 8 or claim 9, it is special Sign is:The shank installing plate (131) is provided with fixed cover baffle plate (135), and the fixed cover baffle plate (135) is covered in described solid Z where fixed set (134) is on the notch of shank neck (133).
CN201720260916.XU 2017-03-16 2017-03-16 Multi-needle magnetic particle chemiluminescence immunoassay analyzer test solution suction device Active CN206638610U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109374910A (en) * 2018-10-16 2019-02-22 基蛋生物科技股份有限公司 Cleaning arm and analysis and test device
TWI760720B (en) * 2019-03-28 2022-04-11 南韓商Lg化學股份有限公司 Immunoassay method and immunoassay device
CN115446032A (en) * 2022-09-15 2022-12-09 长沙海柯生物科技有限公司 Liquid adding cleaning structure and liquid adding cleaning method for liquid sucking needle of immunoassay analyzer

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109374910A (en) * 2018-10-16 2019-02-22 基蛋生物科技股份有限公司 Cleaning arm and analysis and test device
TWI760720B (en) * 2019-03-28 2022-04-11 南韓商Lg化學股份有限公司 Immunoassay method and immunoassay device
CN115446032A (en) * 2022-09-15 2022-12-09 长沙海柯生物科技有限公司 Liquid adding cleaning structure and liquid adding cleaning method for liquid sucking needle of immunoassay analyzer
CN115446032B (en) * 2022-09-15 2023-11-10 长沙海柯生物科技有限公司 Liquid adding and cleaning structure and liquid adding and cleaning method for liquid suction needle of immunity analyzer

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