CN107802582A - A kind of net white skin care compositions, its preparation method and the net white skin care item containing said composition containing birds nest extract - Google Patents

A kind of net white skin care compositions, its preparation method and the net white skin care item containing said composition containing birds nest extract Download PDF

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Publication number
CN107802582A
CN107802582A CN201711312499.XA CN201711312499A CN107802582A CN 107802582 A CN107802582 A CN 107802582A CN 201711312499 A CN201711312499 A CN 201711312499A CN 107802582 A CN107802582 A CN 107802582A
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extract
skin care
parts
white skin
net white
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王飞
王一飞
陈海佳
葛啸虎
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of net white skin care compositions containing birds nest extract, its preparation method and net white skin care item containing said composition.The net white skin care compositions containing birds nest extract, it is characterised in that the net white skin care compositions contains birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey.Compounded in the present invention using various active composition, there is the cooperative effect of net pale skin, the formation of tyrosinase activity and melanin can be suppressed, net white skin makeup.

Description

A kind of net white skin care compositions, its preparation method containing birds nest extract and contain this The net white skin care item of composition
Technical field
The present invention relates to skin care field, and in particular to a kind of net white skin care compositions containing birds nest extract, its preparation Method and the net white skin care item containing said composition.
Background technology
In recent years, as the factors such as the aging of population, environmental pollution, global warning, the skin of people occur increasingly The problem of more, be subjected to skin pigmentation disorder, the puzzlement for the skin problems such as foxiness, freckle occur, whitening only white skin care item by more Carry out the favor of more female friends.Whitening only white skin care item principle be mainly suppress human body in tyrosinase activity so as to The formation of melanin is controlled, although the species of the whitening product of in the market is on the increase, is all contained in most of whitening products There is chemical composition, there is negative effect to human body, some even contains carcinogenic components, the whitening effect of also a large amount of Skin whitening care cosmeticses Bad, stability is poor.
The content of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of net white skincare composition containing birds nest extract Thing.
It is another object of the present invention to provide a kind of preparation method of the net white skin care compositions containing birds nest extract.
It is another object of the present invention to provide a kind of net white skin care item and preparation method thereof.
A kind of net white skin care compositions containing birds nest extract, the net white skin care compositions contain birds nest extract, apple Berry extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey.
Birds nest extract is rich in activated protein in above-mentioned skin care compositions, has unique whitening and softening skin, beautifying face and moistering lotion, changes The effect of kind skin.Apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract are all natural Whitening agent, effectively suppress the formation of tyrosinase activity and melanin, so as to reach the purpose of net white muscle skin.Honey can moisten Skin, moisturizing supplement skin, make skin smooth exquisiteness, elastic force only white.Above various active composition compounds, and has net pale skin Cooperative effect, suppress the formation of tyrosinase activity and melanin, net white skin makeup.
As the preferred embodiment of the net white skin care compositions of the present invention containing birds nest extract, the net white shield Skin composition contains following components in parts by weight:0.8~5 part of birds nest extract, 10~16 parts of apple extract, lavender extraction 12~20 parts of thing, 3~9 parts of Turmeric P.E, 1~6 part of safflower extract, 0.5~4 part of Fructus Litchi extract and honey 10~20 Part.
As the preferred embodiment of the net white skin care compositions of the present invention containing birds nest extract, the net white shield Skin composition contains following components in parts by weight:2.0~3.5 parts of birds nest extract, 12~15 parts of apple extract, lavender carry Take 15~18 parts of thing, 5~8 parts of Turmeric P.E, 3~5 parts of safflower extract, 1.5~2.5 parts of Fructus Litchi extract and honey 15~ 18 parts.
As the preferred embodiment of the net white skin care compositions of the present invention containing birds nest extract, the net white shield Skin composition contains following components in parts by weight:2.7 parts of birds nest extract, 13 parts of apple extract, 16 parts of Herba Lysimachiae foenumgraeci extract, 16 parts of 6 parts of Turmeric P.E, 4 parts of safflower extract, 1.8 parts of Fructus Litchi extract and honey.
Present invention also offers a kind of preparation method of the above-mentioned net white skin care compositions containing birds nest extract, including with Lower step:
(1) take bird's nest to be mixed with 30~35 DEG C of deionized water, soak 3h, filter residue be collected by filtration, by the filter residue of collection- 80 DEG C of 1~2h of freezing, melt 0.5~1h at 20~25 DEG C, filter and collect filter residue, repeat freeze thawing, filtering and collect filter residue Operation 3 times, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, obtains concentrate, birds nest extract is obtained after freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
Present invention also offers a kind of net white skin care item, the skin care item contain net described in any one of Claims 1 to 4 White skin care compositions.
As the preferred embodiment of net white skin care item of the present invention, the skin care item are also containing NMF, emulsification Agent, thickener, oil phase component and deionized water.
As the preferred embodiment of net white skin care item of the present invention, the skin care item contain following percetage by weight Component:Net white skin care compositions 1.5%~5.5%, NMF 0.9%~4%, breast described in any one of Claims 1 to 4 Agent 1%~2.5%, thickener 0.25%~1.0%, oil phase component 3%~5% and deionized water surplus.
As the preferred embodiment of net white skin care item of the present invention, the NMF is hyaluronic acid, marine alga is more Sugar, glycerine, butanediol, hexylene glycol, at least one of triol;The emulsifying agent be cetostearyl alcohol, alkyl glucoside, At least one of lauric acid amide of ethanol, monoolein, Emulsifier EL-60;Thickener is xanthan gum, card ripple Nurse, hydroxypropyl cellulose or hydroxyethyl cellulose;The oil phase component is jojoba oil, hydrogenated coco, shea butter or hydrogenation Castor oil.
Present invention also offers the preparation method of above-mentioned net white skin care item, comprise the following steps:
1) each component raw material is weighed in proportion;
2) NMF and thickener are dissolved in deionized water, are heated with stirring to 75~85 DEG C, are sufficiently stirred, obtain water Phase;
3) oil phase component and emulsifier for mixing are heated to 75~85 DEG C, obtain oil phase;
4) oil phase is added in aqueous phase under stirring, after emulsifying is uniform, is cooled to 40~45 DEG C, then added Enter the net white skin care compositions, be sufficiently stirred, be cooled to room temperature, obtain the net white skin care item.
Prior art is compared, the invention has the advantages that:
Above-mentioned skin care compositions and skin care item are using birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, turmeric extraction Thing, safflower extract, Fructus Litchi extract and honey various active composition compounding, birds nest extract are rich in activated protein, have only Special whitening and softening skin, beautifying face and moistering lotion, the effect of improving skin.Apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower Extract, Fructus Litchi extract are all natural whitening agents, effectively suppress the formation of tyrosinase activity and melanin, so as to reach The purpose of net white muscle skin.Honey energy skin care, moisturizing supplement skin, make skin smooth exquisiteness, elastic force only white.Various active into Divide compounding, the cooperative effect with net pale skin, the formation of tyrosinase activity and melanin can be suppressed, net white skin makeup.
Embodiment
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment to the present invention Further illustrate.It will be appreciated by those skilled in the art that specific embodiment described herein is only to explain the present invention, not For limiting the present invention.
Test method used in following embodiments is conventional method unless otherwise specified;Institute in following embodiments The material that uses, reagent etc., unless otherwise specified, are commercially obtained.
Apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract are excellent large purchased from Xi'an Bio tech ltd.
Embodiment 1
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:2.7 parts of birds nest extract, 13 parts of apple extract, lavender carry Take 16 parts of 16 parts of thing, 6 parts of Turmeric P.E, 4 parts of safflower extract, 1.8 parts of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) bird's nest and 30 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, will receive The filter residue of collection freezes 1h at -80 DEG C, melts 1h at 25 DEG C, filters and collect filter residue, repeats freeze thawing, filtering and the behaviour for collecting filter residue Make 3 times, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
Embodiment 2
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:2.0 parts of birds nest extract, 12 parts of apple extract, lavender carry Take 18 parts of 18 parts of thing, 5 parts of Turmeric P.E, 3 parts of safflower extract, 1.5 parts of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) bird's nest and 30~35 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, The filter residue of collection is freezed into 2h at -80 DEG C, melts 0.5h at 20 DEG C, filters and collect filter residue, freeze thawing, filtering is repeated and collects filter The operation of slag 3 times, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
Embodiment 3
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:3.5 parts of birds nest extract, 15 parts of apple extract, lavender carry Take 15 parts of 15 parts of thing, 8 parts of Turmeric P.E, 5 parts of safflower extract, 2.5 parts of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) bird's nest and 30~35 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, The filter residue of collection is freezed into 1~2h at -80 DEG C, melts 0.5~1h at 20~25 DEG C, filters and collect filter residue, repeat freeze thawing, mistake Filter and the operation 3 times for collecting filter residue, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
Embodiment 4
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:0.8 part of birds nest extract, 16 parts of apple extract, lavender carry Take 20 parts of 12 parts of thing, 9 parts of Turmeric P.E, 1 part of safflower extract, 0.5 part of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) bird's nest and 35 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, will receive The filter residue of collection freezes 1.5h at -80 DEG C, melts 0.5h at 25 DEG C, filters and collect filter residue, repeats freeze thawing, filtering and collects filter residue Operation 3 times, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
Embodiment 5
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:5 parts of birds nest extract, 10 parts of apple extract, lavender extraction 10 parts of 20 parts of thing, 3 parts of Turmeric P.E, 6 parts of safflower extract, 4 parts of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract is described in the present embodiment:
(1) bird's nest and 30~35 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, The filter residue of collection is freezed into 1.5h at -80 DEG C, melts 0.75h at 20~25 DEG C, filters and collect filter residue, repeats freeze thawing, filtering With the operation 3 times for collecting filter residue, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee are carried Take thing and honey to mix in proportion, obtain the net white skin care compositions.
The NMF be hyaluronic acid, algal polysaccharides, glycerine, butanediol, hexylene glycol, in triol at least one Kind;The emulsifying agent is cetostearyl alcohol, alkyl glucoside, lauric acid amide of ethanol, monoolein, polyoxyethylene castor At least one of sesame oil;Thickener is xanthan gum, carbomer, hydroxypropyl cellulose or hydroxyethyl cellulose;The oil phase group It is divided into jojoba oil, hydrogenated coco, shea butter or rilanit special.
Embodiment 6
A kind of embodiment of net white skin care item of the invention, skin care item described in net white skin care item described in the present embodiment contain following The component of percetage by weight:Net white skin care compositions 5.5%, hyaluronic acid 1%, algal polysaccharides 2% described in claim 1, Cetostearyl alcohol 1%, alkyl glucoside 1%, carbomer 0.50%, jojoba oil 4% and deionized water surplus.
The preparation method of net white skin care item comprises the following steps:
1) each component raw material is weighed in proportion;
2) hyaluronic acid, algal polysaccharides and carbomer are dissolved in deionized water, are heated with stirring to 80 DEG C, are sufficiently stirred, Obtain aqueous phase;
3) jojoba oil, cetostearyl alcohol and alkyl glucoside are heated with stirring to 80 DEG C, obtain oil phase;
4) oil phase is added in aqueous phase under stirring, after emulsifying is uniform, is cooled to 43 DEG C, then added net White skin care compositions, is sufficiently stirred, and is cooled to room temperature, obtains the net white skin care item.
Embodiment 7
A kind of embodiment of net white skin care item of the invention, skin care item described in net white skin care item described in the present embodiment contain following The component of percetage by weight:Net white skin care compositions 4.0%, glycerine 0.9%, coconut oil diethanol described in claim 2 Acid amides 0.5%, monoolein 2.0%, hydroxypropyl cellulose 1.0%, shea butter 3% and deionized water surplus.
The preparation method of net white skin care item comprises the following steps:
1) each component raw material is weighed in proportion;
2) glycerine and hydroxypropyl cellulose are dissolved in deionized water, are heated with stirring to 75 DEG C, are sufficiently stirred, obtain water Phase;
3) shea butter, lauric acid amide of ethanol and monoolein are heated with stirring to 75 DEG C, obtain oil phase;
4) oil phase is added in aqueous phase under stirring, after emulsifying is uniform, is cooled to 45 DEG C, then added net White skin care compositions, is sufficiently stirred, and is cooled to room temperature, obtains the net white skin care item.
Embodiment 8
A kind of embodiment of net white skin care item of the invention, skin care item described in net white skin care item described in the present embodiment contain following The component of percetage by weight:Net white skin care compositions 1.5%, butanediol 1%, hexylene glycol 1% described in claim 3, three Alcohol 2%, Emulsifier EL-60 1%, xanthan gum 0.25%, hydrogenated coco 5% and deionized water surplus.
The preparation method of net white skin care item comprises the following steps:
1) each component raw material is weighed in proportion;
2) butanediol, hexylene glycol, triol and xanthan gum are dissolved in deionized water, are heated with stirring to 85 DEG C, fully stir Mix, obtain aqueous phase;
3) hydrogenated coco and Emulsifier EL-60 are heated with stirring to 85 DEG C, obtain oil phase;
4) oil phase is added in aqueous phase under stirring, after emulsifying is uniform, is cooled to 40 DEG C, then added net White skin care compositions, is sufficiently stirred, and is cooled to room temperature, obtains the net white skin care item.
Comparative example 1
The net white skin care compositions containing birds nest extract includes following parts by weight of component described in this comparative example:Apple extract 16 parts of 13 parts, 16 parts of Herba Lysimachiae foenumgraeci extract, 6 parts of Turmeric P.E, 4 parts of safflower extract, 1.8 parts of Fructus Litchi extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey are pressed Ratio is well mixed, and obtains the net white skin care compositions.
Comparative example 2
A kind of embodiment of net white skin care compositions of the present invention containing birds nest extract, extracted containing bird's nest described in the present embodiment The net white skin care compositions of thing includes following parts by weight of component:16 parts of 2.7 parts of birds nest extract and honey.
The preparation method of the net white skin care compositions containing birds nest extract, comprises the following steps described in the present embodiment:
(1) bird's nest and 30 DEG C of deionized water are taken by 1g:20mL ratio mixing, immersion 3h, are collected by filtration filter residue, will receive The filter residue of collection freezes 1h at -80 DEG C, melts 1h at 25 DEG C, filters and collect filter residue, repeats freeze thawing, filtering and the behaviour for collecting filter residue Make 3 times, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected into obtained filter residue mix with neutral proteinase, digests and obtain digestive juice, by digestive juice and The filtrate mixing concentration that step (1) is collected, concentrate is obtained, birds nest extract is obtained after freeze-dried machine freeze-drying;
(3) birds nest extract and honey are mixed in proportion, obtains the net white skin care compositions.
Skin care compositions and skin care item efficacy assessments
First, to the suppression of tyrosinase activity
After skin care compositions prepared by embodiment 1, comparative example 1 and comparative example 2 is placed into 10 days and 6 months respectively, measure Its inhibiting rate to tyrosinase activity.
Experimental method is with reference to pertinent literature (the strong the black pigment of skin genetic analysis of Wang Bai and whitening effect appraisement system [J] Chemical Engineerings are studied with equipping, 2008, (02):14-18.[2017-09-29].).Prepare each group reaction solution, 37 DEG C of constant temperature Water-bath, tyrosinase is added in tyrosine solution, be by determining concentration by ELIASA (MultiskanFC, Thermo) Absorbance of the 1.0% whitening and skin-protecting composition solution at 475nm, place 10 days and whitening and skin-protecting composition pair after 6 months The inhibiting rate result of tyrosinase activity is as shown in table 1.
Table 1
Standing time Embodiment 1 Comparative example 1 Comparative example 2
10 days 93.5% 86.2% 74.6%
6 months 90.7% 81.6% 65.4%
Tyrosine is the primary raw material for manufacturing melanocyte, and tyrosinase is then the crucial rate-limiting enzyme that tyrosine is changed into melanocyte, Therefore generation of the tyrosinase to the black pigment of skin has material impact, and the inhibiting rate to tyrosinase activity is also to weigh skin care The important evidence of product freckle effect.As it can be seen from table 1 net white skin care compositions prepared by embodiment 1 is to tyrosinase activity The skin care compositions that is prepared apparently higher than comparative example 1 and comparative example 2 of inhibiting rate, show birds nest extract, apple extract, smoke Clothing grass extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey can improve net white skin care compositions to junket ammonia The rejection ability of phytase activity, and net white suppression of the skin care compositions to tyrosinase activity that prepared by comparative example 2 after placing 6 months Rate processed shows more obviously to decline, and shows apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee Extract can remove peroxy radical in time, prevent from suppressing tyrosine enzyme activity in other extracts as natural Property active ingredient Oxidative inactivation, strengthen whitening effect.
2nd, permeability experiment
Using whitening and skin-protecting composition prepared by embodiment 1 as experimental group, comparative example 1~2 prepares net white skin care compositions Permeability experiment is carried out as a control group.Permeability experiment method and step is with reference to pertinent literature (the red nanometers containing shea butter of Chen Liang The technology of preparing of emulsion and its application study [D] Shanghai Institute Of Technology, 2015.), experimental result is as shown in table 2.
Table 2
As shown in Table 2, the permeability of embodiment 1 is better than comparative example 1 and comparative example 2.As a result show, birds nest extract, apple The addition of berry extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey, improve skin care group To the permeability and absorbability of skin, it was applied to after skin in the short time compound, made with regard to that can penetrate into skin skin corium, and by cell For nutrient absorption, participate in and promote cell metabolism, moisten moisturizing, lift whitening effect.
3rd, whitening effect determines
The selection age is tested for the healthy women of 18~40 years old as subject, by 3 groups, every group of subject's average mark 30 people, the net white skin care item of embodiments of the invention 6~8 are used after daily face cleaning, start before experiment and skin is utilized after 6 months Colorimetric instrument (the LAB skins colorimeter systems of DSM II) measurement uses the colourity of skin before and after whitening and skin-protecting composition, is calculated Colour difference, colour difference think there is obvious whitening effect more than 1.5, as a result as shown in table 3.
Table 3
Group Embodiment 6 Embodiment 7 Embodiment 8
Colour difference 2.91 2.66 2.58
As can be seen from Table 3, after the net white skin care item prepared by the embodiment of the present invention 6~8 use 6 months, colourity Difference is more than 1.5, shows the net white skin care item of the present invention and has good whitening effect, and by adjusting birds nest extract, apple Compound proportion between extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey, can be with Obtain the preferably net white skin care item of whitening effect.
The above results show that net white skin care compositions prepared by the present invention has good inhibitory action to tyrosinase, have Whitening effect, carried using birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, lichee Thing and honey various active composition is taken to compound, birds nest extract is rich in activated protein, has unique whitening and softening skin, and beauty is supported Face, improve skin the effect of.Apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract are all It is natural whitening agent, effectively suppresses the formation of tyrosinase activity and melanin, so as to reach the purpose of net white muscle skin.Honey Energy skin care, moisturizing supplement skin, make skin smooth exquisiteness, elastic force only white.Various active composition compounds, and has net pale skin Cooperative effect, the formation of tyrosinase activity and melanin can be suppressed, net white skin makeup.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (10)

1. a kind of net white skin care compositions containing birds nest extract, it is characterised in that the net white skin care compositions contains bird's nest Extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract and honey.
2. the net white skin care compositions according to claim 1 containing birds nest extract, it is characterised in that the net white skin care Composition contains following components in parts by weight:0.8~5 part of birds nest extract, 10~16 parts of apple extract, Herba Lysimachiae foenumgraeci extract 10~20 parts of 12~20 parts, 3~9 parts of Turmeric P.E, 1~6 part of safflower extract, 0.5~4 part of Fructus Litchi extract and honey.
3. the net white skin care compositions according to claim 1 containing birds nest extract, it is characterised in that the net white skin care Composition contains following components in parts by weight:2.0~3.5 parts of birds nest extract, 12~15 parts of apple extract, lavender extraction 15~18 parts of thing, 5~8 parts of Turmeric P.E, 3~5 parts of safflower extract, 1.5~2.5 parts of Fructus Litchi extract and honey 15~18 Part.
4. the net white skin care compositions according to claim 1 containing birds nest extract, it is characterised in that the net white skin care Composition contains following components in parts by weight:2.7 parts of birds nest extract, 13 parts of apple extract, 16 parts of Herba Lysimachiae foenumgraeci extract, ginger 16 parts of yellow 6 parts of extract, 4 parts of safflower extract, 1.8 parts of Fructus Litchi extract and honey.
5. the preparation method of the net white skin care compositions containing birds nest extract according to any one of Claims 1 to 4, it is special Sign is, comprises the following steps:
(1) take bird's nest to be mixed with 30~35 DEG C of deionized water, soak 3h, filter residue is collected by filtration, by the filter residue of collection at -80 DEG C 1~2h is freezed, melts 0.5~1h at 20~25 DEG C, filters and collect filter residue, repeats freeze thawing, filtering and the operation 3 for collecting filter residue It is secondary, collect obtain filtrate and filter residue respectively;
(2) step (1) is collected to obtained filter residue to mix with neutral proteinase, enzymolysis obtains digestive juice, by digestive juice and step (1) the filtrate mixing concentration collected, obtains concentrate, birds nest extract is obtained after freeze-drying;
(3) by birds nest extract, apple extract, Herba Lysimachiae foenumgraeci extract, Turmeric P.E, safflower extract, Fructus Litchi extract Mixed in proportion with honey, obtain the net white skin care compositions.
6. a kind of net white skin care item, it is characterised in that the skin care item contain the net white shield described in any one of Claims 1 to 4 Skin composition.
7. net white skin care item according to claim 6, it is characterised in that the skin care item also containing NMF, emulsifying agent, Thickener, oil phase component and deionized water.
8. net white skin care item according to claim 7, it is characterised in that the skin care item contain following percetage by weight Component:Net white skin care compositions 1.5%~5.5% described in any one of Claims 1 to 4, NMF 0.9%~4%, emulsification Agent 1%~2.5%, thickener 0.25%~1.0%, oil phase component 3%~5% and deionized water surplus.
9. net white skin care item according to claim 7, it is characterised in that the NMF be hyaluronic acid, algal polysaccharides, Glycerine, butanediol, hexylene glycol, at least one of triol;The emulsifying agent is cetostearyl alcohol, alkyl glucoside, coconut palm At least one of oleic acid diethyl amide, monoolein, Emulsifier EL-60;Thickener be xanthan gum, carbomer, Hydroxypropyl cellulose or hydroxyethyl cellulose;The oil phase component is jojoba oil, hydrogenated coco, shea butter or hydrogenated castor Oil.
10. the preparation method of net white skin care item according to claim 7, it is characterised in that comprise the following steps:
1) each component raw material is weighed in proportion;
2) NMF and thickener are dissolved in deionized water, are heated with stirring to 75~85 DEG C, are sufficiently stirred, obtain aqueous phase;
3) oil phase component and emulsifier for mixing are heated to 75~85 DEG C, obtain oil phase;
4) oil phase is added in aqueous phase under stirring, after emulsifying is uniform, is cooled to 40~45 DEG C, then adds institute Net white skin care compositions is stated, is sufficiently stirred, is cooled to room temperature, obtains the net white skin care item.
CN201711312499.XA 2017-12-08 2017-12-08 A kind of net white skin care compositions, its preparation method and the net white skin care item containing said composition containing birds nest extract Withdrawn CN107802582A (en)

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CN108653170A (en) * 2018-06-28 2018-10-16 燕生(福建)生物工程有限公司 One kind composition of preserving moisture and protecting skin containing birds nest extract and its processing technology
CN110833523A (en) * 2019-11-25 2020-02-25 广州元美盛化妆品有限公司 Whitening composition and preparation method thereof
CN111265465A (en) * 2020-04-01 2020-06-12 广州今盛美精细化工有限公司 Cubilose extract and application thereof in preparation of cosmetics

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN108653170A (en) * 2018-06-28 2018-10-16 燕生(福建)生物工程有限公司 One kind composition of preserving moisture and protecting skin containing birds nest extract and its processing technology
CN110833523A (en) * 2019-11-25 2020-02-25 广州元美盛化妆品有限公司 Whitening composition and preparation method thereof
CN111265465A (en) * 2020-04-01 2020-06-12 广州今盛美精细化工有限公司 Cubilose extract and application thereof in preparation of cosmetics

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