CN111265465A - Cubilose extract and application thereof in preparation of cosmetics - Google Patents
Cubilose extract and application thereof in preparation of cosmetics Download PDFInfo
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- CN111265465A CN111265465A CN202010251473.4A CN202010251473A CN111265465A CN 111265465 A CN111265465 A CN 111265465A CN 202010251473 A CN202010251473 A CN 202010251473A CN 111265465 A CN111265465 A CN 111265465A
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- cubilose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention discloses a cubilose extract and application thereof in preparing cosmetics, comprising the following steps: s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen; s2, adding clear water into the filtered bird' S nest, soaking for 10-30 min, boiling at normal temperature, and stirring while boiling; s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice; s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain concentrated solution, drying to obtain the cubilose extract, further processing the cubilose extract to ensure the activity and purity of protein in the cubilose extract and improve the product quality of the cubilose extract.
Description
Technical Field
The invention relates to the technical field of cubilose extracts and application thereof, in particular to a cubilose extract and application thereof in preparing cosmetics.
Background
The nidus Collocaliae is nest built by mixing and coagulating saliva and down feather of swiftlet of Potiria of Asteridae, also called swallow root and swallow vegetable. It is mainly produced in the islands of south China sea and countries of south east Asia. The bird's nest has high nutrition and is one of the traditional famous and precious foods in China.
The modern medical research of the cubilose discovers that the main components of the cubilose comprise water-soluble protein and carbohydrate; the trace elements include calcium, phosphorus, iron, sodium, potassium and amino acids playing an important role in promoting the vitality of human bodies. The unique bioactive molecules with protein component content in cubilose are helpful for the growth, development and recovery of human tissues after diseases.
However, the existing cubilose extract has complex process and low product yield after being prepared into cosmetics, and the cubilose extract has low content of beauty active ingredients and excessive impurities in the contained active ingredients, so that the cubilose extract and the application thereof in preparing the cosmetics are provided for solving the problems.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a cubilose extract and application thereof in preparing cosmetics.
A nidus Collocaliae extract is prepared by the following steps:
s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen;
s2, adding clear water into the filtered bird' S nest, soaking for 10-30 min, boiling at normal temperature, and stirring while boiling;
s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice;
s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain a concentrated solution, and drying to obtain the cubilose extract.
Preferably, the mesh number of the filter screen in the S1 is 100-150 meshes.
Preferably, the weight of the added clear water in the S2 is that the weight ratio of the cubilose is 1: 150-200, and the cooking time is 10-20 min.
Preferably, the enzyme activity of the neutral protease in the S3 is 50 ten thousand U/g, and the enzymolysis time is 5-10 h.
Preferably, the mass ratio of the neutral protease added into S3 to the solution obtained from S2 is 1-3: 5.
the application of the cubilose extract in preparing cosmetics comprises the following raw materials in percentage by mass:
2-20% of cubilose extract, 1-5% of mineral oil, 1-5% of vegetable oil, 1-2% of animal oil, 2-6% of emulsifier, 2-10% of humectant, 0.05-0.1% of preservative, 0.01-0.1% of antioxidant and the balance of deionized water;
the mineral oil is a mixture of stearic acid and white oil, and the mass ratio of stearic acid to white oil is 4: 1;
the vegetable oil is a mixture of sweet almond oil and olive oil, and the mass ratio of the sweet almond oil to the olive oil is 1: 2;
the humectant is a mixture consisting of glycerol and butanediol, and the mass ratio of the glycerol to the butanediol is 1: 3;
the preservative is a mixture consisting of methyl paraben and propyl paraben, and the mass ratio of the methyl paraben to the propyl paraben is 2: 1;
preferably, the method comprises the following steps:
r1, heating oil consisting of mineral oil ester and emulsifier, and stirring to dissolve to obtain A1 phase;
r2, heating oil consisting of vegetable oil and fat and an antioxidant, stirring and dissolving to obtain an A2 phase;
r3, dissolving the cubilose extract composition in deionized water, and heating and preserving the temperature to obtain a solution as a B1 phase;
r4, dissolving the humectant in the balance of deionized water, heating and stirring until the humectant is completely dissolved to obtain a solution serving as a B2 phase;
r5, controlling the temperature to be 70-85 ℃, mixing and uniformly stirring the A1 phase and the A2 phase obtained from R1 and R2 to obtain a total oil phase serving as an A phase;
r6, mixing the B2 phase and the A phase obtained from R4 and R5 by a stirrer, and uniformly stirring;
r7, cooling the mixture prepared by R6 to 50-70 ℃, mixing with B1 prepared by R3, and stirring uniformly;
and R8, naturally cooling the mixture in the R7 to a certain temperature, adding the preservative, continuously stirring until the mixture is uniformly mixed, naturally cooling to room temperature, and stopping stirring.
Preferably, the heating temperature in the R1 is 60-90 ℃, the heating temperature in the R2 is 60-90 ℃, the heating temperature in the R3 is 50-70 ℃, and the heating temperature in the R4 is 60-90 ℃.
The invention has the beneficial effects that:
before the cosmetic is prepared, the cubilose extract is further processed to ensure the activity and purity of protein in the cubilose extract, and the cubilose extract is digested by neutral protease, so that the obtained cubilose extract has unique efficacies of whitening and tendering skin, beautifying and protecting health, removing freckles and dirt, promoting blood circulation, improving skin and the like, and the product quality is improved.
Detailed Description
The present invention will be further illustrated with reference to the following specific examples.
The first embodiment is as follows:
a nidus Collocaliae extract is prepared by the following steps:
s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen;
s2, adding clear water into the filtered bird' S nest, soaking for 10min, boiling at normal temperature, and stirring while boiling;
s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice;
s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain a concentrated solution, and drying to obtain the cubilose extract.
Further, the mesh number of the filter screen in the S1 is 100 meshes.
Further, the weight of the clean water added in the S2 is that the weight ratio of the cubilose is 1: 150, and the cooking time is 10 min.
Further, the enzyme activity of the neutral protease in the S3 is 50 ten thousand U/g, and the enzymolysis time is 5 h.
Furthermore, the mass ratio of the neutral protease added into the S3 to the solution obtained in the S2 is 1-3.
The application of the cubilose extract in preparing cosmetics comprises the following raw materials in percentage by mass:
2-20% of cubilose extract, 1-5% of mineral oil, 1-5% of vegetable oil, 1-2% of animal oil, 2-6% of emulsifier, 2-10% of humectant, 0.05-0.1% of preservative, 0.01-0.1% of antioxidant and the balance of deionized water;
the mineral oil is a mixture of stearic acid and white oil, and the mass ratio of stearic acid to white oil is 4: 1;
the vegetable oil is a mixture of sweet almond oil and olive oil, and the mass ratio of the sweet almond oil to the olive oil is 1: 2;
the humectant is a mixture consisting of glycerol and butanediol, and the mass ratio of the glycerol to the butanediol is 1: 3;
the preservative is a mixture consisting of methyl paraben and propyl paraben, and the mass ratio of the methyl paraben to the propyl paraben is 2: 1;
further, the method comprises the following steps:
r1, heating oil consisting of mineral oil ester and emulsifier, and stirring to dissolve to obtain A1 phase;
r2, heating oil consisting of vegetable oil and fat and an antioxidant, stirring and dissolving to obtain an A2 phase;
r3, dissolving the cubilose extract composition in deionized water, and heating and preserving the temperature to obtain a solution as a B1 phase;
r4, dissolving the humectant in the balance of deionized water, heating and stirring until the humectant is completely dissolved to obtain a solution serving as a B2 phase;
r5, controlling the temperature at 70 ℃, mixing the A1 phase and the A2 phase obtained from R1 and R2, and uniformly stirring to obtain a total oil phase as an A phase;
r6, mixing the B2 phase and the A phase obtained from R4 and R5 by a stirrer, and uniformly stirring;
r7, cooling the mixture prepared by R6 to 50 ℃, mixing with B1 prepared by R3, and stirring uniformly;
and R8, naturally cooling the mixture in the R7 to a certain temperature, adding the preservative, continuously stirring until the mixture is uniformly mixed, naturally cooling to room temperature, and stopping stirring.
Further, the heating temperature in the R1 is 60 ℃, the heating temperature in the R2 is 60 ℃, the heating temperature in the R3 is 50 ℃, and the heating temperature in the R4 is 60 ℃.
Example two:
a nidus Collocaliae extract is prepared by the following steps:
s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen;
s2, adding clear water into the filtered bird' S nest, soaking for 20min, boiling at normal temperature, and stirring while boiling;
s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice;
s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain a concentrated solution, and drying to obtain the cubilose extract.
Further, the mesh number of the filter screen in the S1 is 120 meshes.
Further, the weight of the clean water added in the S2 is that the weight ratio of the cubilose is 1: 180 and the cooking time is 15 min.
Further, the enzyme activity of the neutral protease in the S3 is 50 ten thousand U/g, and the enzymolysis time is 7 h.
Furthermore, the mass ratio of the neutral protease added into the S3 to the solution obtained in the S2 is 1-4.
The application of the cubilose extract in preparing cosmetics comprises the following raw materials in percentage by mass:
2-20% of cubilose extract, 1-5% of mineral oil, 1-5% of vegetable oil, 1-2% of animal oil, 2-6% of emulsifier, 2-10% of humectant, 0.05-0.1% of preservative, 0.01-0.1% of antioxidant and the balance of deionized water;
the mineral oil is a mixture of stearic acid and white oil, and the mass ratio of stearic acid to white oil is 4: 1;
the vegetable oil is a mixture of sweet almond oil and olive oil, and the mass ratio of the sweet almond oil to the olive oil is 1: 2;
the humectant is a mixture consisting of glycerol and butanediol, and the mass ratio of the glycerol to the butanediol is 1: 3;
the preservative is a mixture consisting of methyl paraben and propyl paraben, and the mass ratio of the methyl paraben to the propyl paraben is 2: 1;
further, the method comprises the following steps:
r1, heating oil consisting of mineral oil ester and emulsifier, and stirring to dissolve to obtain A1 phase;
r2, heating oil consisting of vegetable oil and fat and an antioxidant, stirring and dissolving to obtain an A2 phase;
r3, dissolving the cubilose extract composition in deionized water, and heating and preserving the temperature to obtain a solution as a B1 phase;
r4, dissolving the humectant in the balance of deionized water, heating and stirring until the humectant is completely dissolved to obtain a solution serving as a B2 phase;
r5, controlling the temperature at 78 ℃, mixing and uniformly stirring the A1 phase and the A2 phase obtained from R1 and R2 to obtain a total oil phase as an A phase;
r6, mixing the B2 phase and the A phase obtained from R4 and R5 by a stirrer, and uniformly stirring;
r7, cooling the mixture prepared by R6 to 50 ℃, mixing with B1 prepared by R3, and stirring uniformly;
and R8, naturally cooling the mixture in the R7 to a certain temperature, adding the preservative, continuously stirring until the mixture is uniformly mixed, naturally cooling to room temperature, and stopping stirring.
Further, the heating temperature in the R1 is 75 ℃, the heating temperature in the R2 is 75 ℃, the heating temperature in the R3 is 60 ℃, and the heating temperature in the R4 is 75 ℃.
Example three:
a nidus Collocaliae extract is prepared by the following steps:
s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen;
s2, adding clear water into the filtered bird' S nest, soaking for 30min, boiling at normal temperature, and stirring while boiling;
s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice;
s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain a concentrated solution, and drying to obtain the cubilose extract.
Further, the mesh number of the filter screen in the S1 is 150 meshes.
Further, the weight of the clean water added in the S2 is that the weight ratio of the cubilose is 1: 200 and the cooking time is 20 min.
Further, the enzyme activity of the neutral protease in the S3 is 50 ten thousand U/g, and the enzymolysis time is 10 hours.
Furthermore, the mass ratio of the neutral protease added into the S3 to the solution obtained in the S2 is 1-5.
The application of the cubilose extract in preparing cosmetics comprises the following raw materials in percentage by mass:
2-20% of cubilose extract, 1-5% of mineral oil, 1-5% of vegetable oil, 1-2% of animal oil, 2-6% of emulsifier, 2-10% of humectant, 0.05-0.1% of preservative, 0.01-0.1% of antioxidant and the balance of deionized water;
the mineral oil is a mixture of stearic acid and white oil, and the mass ratio of stearic acid to white oil is 4: 1;
the vegetable oil is a mixture of sweet almond oil and olive oil, and the mass ratio of the sweet almond oil to the olive oil is 1: 2;
the humectant is a mixture consisting of glycerol and butanediol, and the mass ratio of the glycerol to the butanediol is 1: 3;
the preservative is a mixture consisting of methyl paraben and propyl paraben, and the mass ratio of the methyl paraben to the propyl paraben is 2: 1;
further, the method comprises the following steps:
r1, heating oil consisting of mineral oil ester and emulsifier, and stirring to dissolve to obtain A1 phase;
r2, heating oil consisting of vegetable oil and fat and an antioxidant, stirring and dissolving to obtain an A2 phase;
r3, dissolving the cubilose extract composition in deionized water, and heating and preserving the temperature to obtain a solution as a B1 phase;
r4, dissolving the humectant in the balance of deionized water, heating and stirring until the humectant is completely dissolved to obtain a solution serving as a B2 phase;
r5, controlling the temperature to be 70-85 ℃, mixing and uniformly stirring the A1 phase and the A2 phase obtained from R1 and R2 to obtain a total oil phase serving as an A phase;
r6, mixing the B2 phase and the A phase obtained from R4 and R5 by a stirrer, and uniformly stirring;
r7, cooling the mixture prepared by R6 to 70 ℃, mixing with B1 prepared by R3, and stirring uniformly;
and R8, naturally cooling the mixture in the R7 to a certain temperature, adding the preservative, continuously stirring until the mixture is uniformly mixed, naturally cooling to room temperature, and stopping stirring.
Further, the heating temperature in the R1 is 90 ℃, the heating temperature in the R2 is 90 ℃, the heating temperature in the R3 is 70 ℃, and the heating temperature in the R4 is 90 ℃.
In conclusion, the cubilose extract contains various components beneficial to human bodies, and when the cubilose extract is used for preparing cosmetics, the obtained cubilose extract has unique effects of whitening and tendering skin, beautifying and protecting health, removing freckles and dirt, promoting blood circulation, improving skin and the like, and the quality of products is improved.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (8)
1. The cubilose extract is characterized in that the preparation method comprises the following steps:
s1, crushing the dried cubilose by a crusher, and filtering the crushed cubilose by a filter screen;
s2, adding clear water into the filtered bird' S nest, soaking for 10-30 min, boiling at normal temperature, and stirring while boiling;
s3, slowly cooling the solution to room temperature, adjusting the pH value to be neutral by using a 1-10% sodium carbonate solution, and adding neutral protease to carry out enzymolysis on the solution to obtain a digestive juice;
s4, slowly heating the digestive juice to 50-80 ℃, pressurizing and concentrating the digestive juice to obtain a concentrated solution, and drying to obtain the cubilose extract.
2. The cubilose extract as claimed in claim 1, wherein the mesh number of the filter screen in S1 is 100-150 meshes.
3. The cubilose extract as claimed in claim 1, wherein the weight ratio of the clean water added in the S2 to the weight of the cubilose is 1: 150-200, and the cooking time is 10-20 min.
4. The cubilose extract as claimed in claim 1, wherein the enzyme activity of the neutral protease in the S3 is 50 ten thousand U/g, and the enzymolysis time is 5-10 h.
5. The cubilose extract as claimed in claim 1, wherein the mass ratio of the neutral protease added in S3 to the solution obtained in S2 is 1-3: 5.
6. the application of the cubilose extract in preparing cosmetics is characterized in that the cubilose extract comprises the following raw materials in percentage by mass:
2-20% of cubilose extract, 1-5% of mineral oil, 1-5% of vegetable oil, 1-2% of animal oil, 2-6% of emulsifier, 2-10% of humectant, 0.05-0.1% of preservative, 0.01-0.1% of antioxidant and the balance of deionized water;
the mineral oil is a mixture of stearic acid and white oil, and the mass ratio of stearic acid to white oil is 4: 1;
the vegetable oil is a mixture of sweet almond oil and olive oil, and the mass ratio of the sweet almond oil to the olive oil is 1: 2;
the humectant is a mixture consisting of glycerol and butanediol, and the mass ratio of the glycerol to the butanediol is 1: 3;
the preservative is a mixture of methyl-p-hydroxybenzoate and propylparaben, and the mass ratio of the methyl-p-hydroxybenzoate to the propylparaben is 2: 1.
7. The use of the bird's nest extract according to claim 6 in the preparation of cosmetics, characterized by comprising the steps of:
r1, heating oil consisting of mineral oil ester and emulsifier, and stirring to dissolve to obtain A1 phase;
r2, heating oil consisting of vegetable oil and fat and an antioxidant, stirring and dissolving to obtain an A2 phase;
r3, dissolving the cubilose extract composition in deionized water, and heating and preserving the temperature to obtain a solution as a B1 phase;
r4, dissolving the humectant in the balance of deionized water, heating and stirring until the humectant is completely dissolved to obtain a solution serving as a B2 phase;
r5, controlling the temperature to be 70-85 ℃, mixing and uniformly stirring the A1 phase and the A2 phase obtained from R1 and R2 to obtain a total oil phase serving as an A phase;
r6, mixing the B2 phase and the A phase obtained from R4 and R5 by a stirrer, and uniformly stirring;
r7, cooling the mixture prepared by R6 to 50-70 ℃, mixing with B1 prepared by R3, and stirring uniformly;
and R8, naturally cooling the mixture in the R7 to a certain temperature, adding the preservative, continuously stirring until the mixture is uniformly mixed, naturally cooling to room temperature, and stopping stirring.
8. The use of the bird's nest extract in the preparation of cosmetics according to claim 7, characterized in that the heating temperature in R1 is 60-90 ℃, the heating temperature in R2 is 60-90 ℃, the heating temperature in R3 is 50-70 ℃, and the heating temperature in R4 is 60-90 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010251473.4A CN111265465A (en) | 2020-04-01 | 2020-04-01 | Cubilose extract and application thereof in preparation of cosmetics |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010251473.4A CN111265465A (en) | 2020-04-01 | 2020-04-01 | Cubilose extract and application thereof in preparation of cosmetics |
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| CN111265465A true CN111265465A (en) | 2020-06-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010251473.4A Pending CN111265465A (en) | 2020-04-01 | 2020-04-01 | Cubilose extract and application thereof in preparation of cosmetics |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085046A (en) * | 1992-10-04 | 1994-04-13 | 庄永竞 | The enzymatic hydrolysis processing technology and the goods thereof of bird's nest |
| CN103479670A (en) * | 2013-08-30 | 2014-01-01 | 香港科技大学 | Cubilose extracting solution as well as preparation method and application thereof |
| CN104498572A (en) * | 2014-12-05 | 2015-04-08 | 燕之初颜如燕（厦门）生物科技有限公司 | Composite enzymolysis process for cubilose |
| CN104906555A (en) * | 2015-07-09 | 2015-09-16 | 广州赛莱拉干细胞科技股份有限公司 | Preparation method of swallow nest extractive, and obtained swallow nest extractive and application thereof |
| CN107468576A (en) * | 2017-08-30 | 2017-12-15 | 上海应用技术大学 | A kind of composition containing burdock extract and its application in cosmetics |
| CN107802582A (en) * | 2017-12-08 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of net white skin care compositions, its preparation method and the net white skin care item containing said composition containing birds nest extract |
-
2020
- 2020-04-01 CN CN202010251473.4A patent/CN111265465A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1085046A (en) * | 1992-10-04 | 1994-04-13 | 庄永竞 | The enzymatic hydrolysis processing technology and the goods thereof of bird's nest |
| CN103479670A (en) * | 2013-08-30 | 2014-01-01 | 香港科技大学 | Cubilose extracting solution as well as preparation method and application thereof |
| CN104498572A (en) * | 2014-12-05 | 2015-04-08 | 燕之初颜如燕（厦门）生物科技有限公司 | Composite enzymolysis process for cubilose |
| CN104906555A (en) * | 2015-07-09 | 2015-09-16 | 广州赛莱拉干细胞科技股份有限公司 | Preparation method of swallow nest extractive, and obtained swallow nest extractive and application thereof |
| CN107468576A (en) * | 2017-08-30 | 2017-12-15 | 上海应用技术大学 | A kind of composition containing burdock extract and its application in cosmetics |
| CN107802582A (en) * | 2017-12-08 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of net white skin care compositions, its preparation method and the net white skin care item containing said composition containing birds nest extract |
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Application publication date: 20200612 |