CN1077125A - A kind of production method for the treatment of the medicine of coronary heart disease - Google Patents
A kind of production method for the treatment of the medicine of coronary heart disease Download PDFInfo
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- CN1077125A CN1077125A CN93101425A CN93101425A CN1077125A CN 1077125 A CN1077125 A CN 1077125A CN 93101425 A CN93101425 A CN 93101425A CN 93101425 A CN93101425 A CN 93101425A CN 1077125 A CN1077125 A CN 1077125A
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Abstract
The present invention relates to a kind of production method for the treatment of the medicine SHANHAI PILL of coronary heart disease, with Sargassum, Radix Salviae Miltiorrhizae, the Radix Astragali, Semen Cassiae, Radix Ophiopogonis, Fructus Citri Sarcodactylis, Radix Polygoni Multiflori, Rhizoma Cyperi (system), Flos Carthami, Pollen Typhae, Ganoderma, Rhizoma Chuanxiong, Radix Puerariae, decoct with water after-filtration, in medicinal liquid, add Radix Notoginseng, Radix Ginseng, Sanguis Naemorhedi powder mixing, the gained medicine shows through check and clinical practice, total effective rate is 96%, and cure rate is 80%, and without any side effects.
Description
The present invention relates to a kind of prescription and production method for the treatment of the new drug SHANHAI PILL of coronary heart disease, all use Chinese medicine formulated.
Coronary atherosclerotic heart disease is called for short coronary heart disease, and the sickness rate in total population is 7-9 ‰, and is then higher person in middle and old age, is the main cause that causes sudden death clinically.Before the present invention occurred, the Chinese medicine and western medicine of treatment coronary heart disease had: sorbitrate, nifedipine, persantin, second
Iodine skin ketone, diltiazem, slow heart rate, the live heart, SUXIAO JIUXIN WAN, FUFANG DANSHEN PIAN, XIONGDAN JIUXINWAN, storax pill for treating coronary heart disease, NAOXINSHU etc., these medicines are because of all being to pass through blood vessel dilating on pharmacology, temporarily solve the blood supply problem, so short term efficacy is in various degree all arranged, but there is not late result, do not reach the purpose of healing at all, can't fundamentally eliminate patient's misery, and take the drug resistance that all has in various degree for a long time and pay the effect generation.
The production method that the purpose of this invention is to provide a kind of novel medicine, the medicine of producing according to this method has late result again, and finally reaches the healing purpose the existing short term effect of the treatment of coronary heart disease, and does not have the effect of paying of any poison and produce.
The present invention is the new pharmacological action of various institutes of Chinese materia medica being found according to the qi-blood relationship theory of Chinese medicine and modern medicine, finish according to the principle of " symptomatic treatment in acute condition; radical treatment in chronic case; set upright; ' leading to ' just must not hinder; ' benefit ' must not be detained, giving consideration to both the incidental and fundamental, strengthening vital QI to eliminate pathogenic factors " based on reinforcing.
Chinese medicine is thought: the pathogenesis of coronary heart disease generation, many owing to worn with age, deficiency of kidney-QI, and kidney is people's a Yuanyang Kidney-Yin, so further developing, pectoral qi void can cause also void of kidney yang, further develop again and can cause also void of kidney yin, cause kidney Yuanyang Kidney-Yin two Yu, intemperance of taking food, impairing the spleen and stomach, cause deficiency-weakness of spleen-QI, the biochemical general source of pectoral qi, water is wet to be lost in fortuneization, turbid damp is detained in the heart, internal injury caused by excess of seven emotions, qi depression to blood stasis, because of insufficiency of pectoral QI to pass through heart arteries and veins promoting the circulation of blood gas, and the hyperamization row is unfavorable, even blood-stasis internal-depression is pondered over overstrain, injure heart spleen.The traditional Chinese medical science is thought: gas and blood are human body two big matter and energy bases, " qi being the governor of blood; blood being the material foundation of QI ", the normal operation of blood can promote the function of the vital organs of the human body to run well, be obstructed for some reason in passages through which vital energy circulates as QI and blood, just cause " stagnation of QI and blood may bring about pain ", just occur anginal symptom clinically.Modern medicine study proves: Radix Ginseng is except that having central nervous system, hormonal system and the functions of immune system of adjusting, because of it contains the trace element of abundant needed by human, particularly germanium and selenium, so it dredges functions such as microcirculation, anti-senility cancer-preventing in addition; The Radix Astragali also has the function of protection arterial endothelial cell except that having good QI invigorating function, and coronary heart disease to be arterial endothelial cell destroyed, tremulous pulse forms atheromatous plaque; Ganoderma has benefiting QI and nourishing blood and functions such as blood blood stasis dispelling, detoxifcation; Radix Notoginseng is coronary blood flow increasing obviously, reduces myocardial oxygen consumption, blood fat reducing and cholesterol; Sanguis Naemorhedi has effects such as blood circulation promoting and blood stasis dispelling, collateral dredging, detoxifcation; Radix Puerariae, Radix Polygoni Multiflori, Sargassum, Radix Salviae Miltiorrhizae, Semen Cassiae, Rhizoma Chuanxiong, Radix Ophiopogonis, Rhizoma Cyperi (system), Fructus Citri Sarcodactylis, Flos Carthami, Pollen Typhae etc. have coronary blood flow increasing, decreased heart rate reduces myocardial oxygen consumption, improves myocardial oxygen delivery, strengthen myocardial hypoxia tolerance, blood fat reducing, blood sugar lowering etc.
The present invention selects medicine by following prescription.
Radix Notoginseng 200-240g Radix Astragali 1100-2200g
Radix Ginseng 300-340g Flos Carthami 120-160g
Goat blood powder 240-280g Radix Puerariae 620-660g
Radix Polygoni Multiflori 410-450g Sargassum 200-240g
Rhizoma Chuanxiong 410-450g Radix Salviae Miltiorrhizae 620-660g
Radix Ophiopogonis 410-450g Ganoderma 200-240g
Fructus Citri Sarcodactylis 410-450g Pollen Typhae 430-600g
Rhizoma Cyperi (system) 620-660g Semen Cassiae 410-450g
To be ground into the fine powder sieving for standby behind the Radix Notoginseng in the above-mentioned prescription, Radix Ginseng, the Sanguis Naemorhedi airing; 13 flavor Chinese medicines such as Semen Cassiae, Fructus Citri Sarcodactylis, Radix Polygoni Multiflori, Rhizoma Chuanxiong, Radix Ophiopogonis, Rhizoma Cyperi (system), the Radix Astragali, Flos Carthami, Radix Puerariae, Sargassum, Radix Salviae Miltiorrhizae, Ganoderma, Pollen Typhae decoct with water in the general side, filtration back adding 95% ethanol in spissated medicinal liquid makes it to contain the alcohol amount and reaches 60%, the post precipitation recovered alcohol, in spissated medicinal liquid, add Radix Notoginseng, Radix Ginseng, goat blood powder mixing, make the graininess oven dry, incapsulate promptly after granule is sieved.
Domestic and international by retrieval no same or analogous prescription and production technology.
Embodiment:
(1) get Radix Ginseng 316g by above-mentioned prescription, Radix Notoginseng 216g, goat blood powder 252g is ground into the fine powder sieving for standby.(2) get Semen Cassiae, Radix Polygoni Multiflori, Rhizoma Chuanxiong, Radix Ophiopogonis, each 432g of Fructus Citri Sarcodactylis, get Pollen Typhae 600g, get Rhizoma Cyperi (system), Radix Puerariae, each 652g of Radix Salviae Miltiorrhizae, get Radix Astragali 1200g, Flos Carthami 132g, Sargassum 232g, Ganoderma 216g, this 13 flavor Chinese medicine is added water 25000ml in a container, decocted 3 hours, decocted the postpone that cools, get medicinal residues 1 and medicinal liquid 1 after filtration.(3) medicinal residues 1 and water 15000ml were decocted 2 hours in same container, cool postpone filter medicinal residues 2 and medicinal liquid 2.(4) medicinal residues 2 and water 10000ml were decocted 1.5 hours in same container, cool postpone is filtered, and gets medicinal residues 3 and medicinal liquid 3.(5) medicinal liquid 1, medicinal liquid 2, medicinal liquid 3 are merged.(6) medicinal liquid is concentrated into thick paste shape (20 ℃ time proportion 1.38).(7) in medicinal liquid, add 95% ethanol, make it to contain the alcohol amount and reach 60%, and precipitate 24 hours.(8) recovered alcohol.(9) make granule.(10) with medicine oven dry (below 60 ℃).(11) the medicine grain is sieved after, No. 0 capsule (0.5g) of packing into.
The gained medicine carries out acute and chronic toxicity test through the institute for drug control, Xi'an as stated above, proves the medicine avirulence; Stability test through 1 year 06 months proves the medicine stable performance.Shaanxi Province Department of Public Health specifies heart kidney section of No.2 Hospital Attached to No.4 Army's Medical Univ., Xi'an four-player people hospital internal medicine, Xi'an second the People's Hospital's internal medicine, Health Section of engineering college of the Second Artillery Force totally four units the end of the year 987 of in January, 1984 to one, the diagnostic criteria of drafting according in 1979 International Society of Cardiology and cooperative association and World Health Organization's clinical name standardization associating special topic group, select patients with coronary heart disease 500 examples to take by method gained medicine SHANHAI PILL provided by the invention, taking SHANHAI PILL front and back subjective symptoms according to the patient changes, electrocardiogram changes, the inspection contrast of situation of change such as blood viscosity and blood fat obtains significant curative effect.Above-mentioned four units are thought in final report always: the medicine SHANHAI PILL by method provided by the present invention is produced not only has good short term effect to treatment coronary heart disease.And has a very ideal late result; Contrast through the patient with the clothes Western medicine, curative effect is very remarkable.Up to now, by the statistics for the treatment of 12000 routine coronary heart disease is shown: by the medicine SHANHAI PILL that method provided by the present invention is produced, be 96% to treatment coronary heart disease total effective rate, cure rate reaches 80%, and does not have any poison and pay effect.
Claims (2)
1, a kind of production method for the treatment of the medicine of coronary heart disease, it is characterized in that, with Radix Notoginseng, Radix Ginseng, Sanguis Naemorhedi pulverize, in the medicinal liquid of adding by 13 flavor decocting for Chinese herbal medicine gained such as Semen Cassiae, Radix Polygoni Multiflori, Rhizoma Chuanxiong, Radix Ophiopogonis, Fructus Citri Sarcodactylis, Rhizoma Cyperi (system), the Radix Astragali, Flos Carthami, Radix Puerariae, Sargassum, Radix Salviae Miltiorrhizae, Ganoderma, Pollen Typhae, granulate behind the mixing, dry.
2, production method according to claim 1 is characterized in that, each proportionate relationship of distinguishing the flavor of between the medicine is:
Radix Notoginseng 200-240g Radix Astragali 1100-2200g
Radix Ginseng 300-340g Flos Carthami 120-160g
Goat blood powder 240-280g Radix Puerariae 620-660g
Semen Cassiae 410-450g Sargassum 200-240g
Radix Polygoni Multiflori 410-450g Radix Salviae Miltiorrhizae 620-660g
Rhizoma Chuanxiong 410-450g Ganoderma 200-240g
Fructus Citri Sarcodactylis 410-450g Pollen Typhae 430-600g
Rhizoma Cyperi (system) 620-660g 410-450g Radix Ophiopogonis
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101425A CN1028003C (en) | 1993-02-17 | 1993-02-17 | Method of preparing medicine for treatment of coronary heart disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101425A CN1028003C (en) | 1993-02-17 | 1993-02-17 | Method of preparing medicine for treatment of coronary heart disease |
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| Publication Number | Publication Date |
|---|---|
| CN1077125A true CN1077125A (en) | 1993-10-13 |
| CN1028003C CN1028003C (en) | 1995-03-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93101425A Expired - Lifetime CN1028003C (en) | 1993-02-17 | 1993-02-17 | Method of preparing medicine for treatment of coronary heart disease |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051008C (en) * | 1994-09-16 | 2000-04-05 | 韩瑞文 | Chinese medicine composite for coronary heart disease and angina |
| CN102145128A (en) * | 2011-03-30 | 2011-08-10 | 呼伦贝尔松鹿制药有限公司 | Medicinal composition for preventing and treating cardiac and cerebral vascular diseases and preparation method thereof |
| CN104719924A (en) * | 2015-04-11 | 2015-06-24 | 黄佩霞 | Medicated food recipe capable of recuperating patient suffering from coronary heart disease and processing method of medicated food recipe |
-
1993
- 1993-02-17 CN CN93101425A patent/CN1028003C/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1051008C (en) * | 1994-09-16 | 2000-04-05 | 韩瑞文 | Chinese medicine composite for coronary heart disease and angina |
| CN102145128A (en) * | 2011-03-30 | 2011-08-10 | 呼伦贝尔松鹿制药有限公司 | Medicinal composition for preventing and treating cardiac and cerebral vascular diseases and preparation method thereof |
| CN102145128B (en) * | 2011-03-30 | 2012-07-11 | 呼伦贝尔松鹿制药有限公司 | Medicinal composition for preventing and treating cardiac and cerebral vascular diseases and preparation method thereof |
| CN104719924A (en) * | 2015-04-11 | 2015-06-24 | 黄佩霞 | Medicated food recipe capable of recuperating patient suffering from coronary heart disease and processing method of medicated food recipe |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1028003C (en) | 1995-03-29 |
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