CN101745078B - Chinese medicinal composition for treating cardiac failure and preparation method thereof - Google Patents
Chinese medicinal composition for treating cardiac failure and preparation method thereof Download PDFInfo
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- CN101745078B CN101745078B CN2009103099179A CN200910309917A CN101745078B CN 101745078 B CN101745078 B CN 101745078B CN 2009103099179 A CN2009103099179 A CN 2009103099179A CN 200910309917 A CN200910309917 A CN 200910309917A CN 101745078 B CN101745078 B CN 101745078B
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Abstract
The invention discloses a novel Chinese medicinal composition for treating cardiac failure and a preparation method thereof. The Chinese medicinal composition of the invention comprises the following raw material medicaments: kudzu-vine root, tangerine peel, green tangerine peel, immature bitter orange, costustoot, cyperus rotundus, szechwan chinaberry fruit, aspongopus, Chinese eaglewood, cassia bark, medcinal evodia fruit, lesser galangal rhizome, szechuan lovage rhizome, yanhusuo, danshen root, sanchi, safflower, peach seed, motherwort herb, twotooth achyranthes root, common burreed rhizome, zedoary, mix-fried pangolin scales, ginseng, American ginseng, raw raidx astragali, pilose asiabell root, white paeony root, common yam rhizome, Chinese angelica, storax, toad venom, grassleaf sweelflag rhizome, borneol, camphor, musk, Chinese caterpillar fungus, barbary wolfberry fruit, mix-fried turtle shell, mix-fried tortoise plastron, agastache and villous amomum fruit. The Chinese medicinal composition of the invention can be prepared into a normal oral preparation by the common Chinese medicament preparation method. The Chinese medicinal composition can obviously improve these symptoms such as tireness and hypodynamia, decompensation, chest distress, dyspnea, cough, wheezing, limb oedema, jugular vein distention, inappetence, nausea and vomiting, and oliguria etc., and has exact clinical effect and obvious curative effect and quick response. The Chinese medicinal composition of the invention basically adopts medicinal and edible medicaments specified by the National Formulary to carry out combination, thus, the Chinese medicinal composition has the advantages of low price, basically no toxic or side effects and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of cardiac failure.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment cardiac failure of crude drug with the Chinese herbal medicine.
Background technology
Cardiomyopathy, cardiac overload, excited, all easily inducing gas stalk, heart failure disease such as pulmonary infarction repeatedly.Gas stalk, heart failure disease are a kind of clinical symptom groups of complexity, it is the various cardiopathic serious stages, its sickness rate height, 5 annual survival rates are similar to malignant tumor, according to the case history investigation of China 50 tame hospitals, the admission rate of gas stalk, heart failure disease only accounts for cardiovascular diseases's's same period 20%, but mortality rate accounts for 40%, prognosis is serious, and the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment gas stalk, heart failure disease, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out the natural plant of supplementing QI and nourishing YIN, blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.The Chinese medicine composition of a kind of evident in efficacy, with low cost, treatment gas that toxic and side effects is minimum stalk, heart failure disease is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment cardiac failure of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of cardiac failure of the present invention, the component of main following weight portion is formed:
Radix Puerariae 1～300 gram, Pericarpium Citri Reticulatae 1～150 gram, Pericarpium Citri Reticulatae Viride 1～100 gram, Fructus Aurantii Immaturus 1～150 gram, the Radix Aucklandiae 1～100 gram, Rhizoma Cyperi 1～150 gram, Fructus Toosendan 1～150 gram, Aspongopus 1～100 gram, Flos Caryophylli 1～50 gram, Pericarpium Zanthoxyli 1～50 gram, Cortex cinnamomi japonici (Ramulus Cinnamomi) 1～50 gram, the Radix Linderae 1～100 gram, Lignum Aquilariae Resinatum 1～50 gram, Lignum Santali Albi 1～50 gram, Herba Lysimachiae foenum-graeci 1～100 gram, Benzoinum 1～100 gram, Cortex Cinnamomi 1～50 gram, Fructus Evodiae 1～100 gram, Rhizoma Alpiniae Officinarum 1～100 gram, Rhizoma Chuanxiong 1～100 gram, Rhizoma Corydalis 1～100 gram, Radix Salviae Miltiorrhizae 1～100 gram, Radix Notoginseng 1～100 gram, Radix Curcumae 1～100 gram, Rhizoma Curcumae Longae 1～100 gram, Olibanum 1～100 gram, Myrrha 1～100 gram, Flos Carthami 1～50 gram, Semen Persicae 1～50 gram, Herba Leonuri 1～150 gram, Radix Achyranthis Bidentatae 1～150 gram, rhizoma sparganic 1～50 gram, Rhizoma Curcumae 1～50 gram, Squama Manis (processed) 1～50 gram, Radix Ginseng 1～50 gram, Radix Panacis Quinquefolii 1～50 gram, Radix Astragali 1～150 gram, Radix Codonopsis 1～100 gram, the Radix Paeoniae Alba 1～150 gram, Rhizoma Dioscoreae 1～150 gram, Radix Angelicae Sinensis 1～150 gram.
Be preferably:
Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Radix Curcumae 50 grams, Rhizoma Curcumae Longae 40 grams, Olibanum 20 grams, Myrrha 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Styrax 1～100 gram, Venenum Bufonis 1～30 gram, Rhizoma Acori Graminei 1～150 gram, Borneolum Syntheticum 1～30 gram, Camphora 1～30 gram, Moschus 1～10 gram, Cordyceps 1～100 gram, Fructus Alpiniae Oxyphyllae 1～100 gram, Fructus Rosae Laevigatae 1～90 gram, Herba Cistanches 1～100 gram, Radix Rehmanniae Preparata 1～150 gram, Radix Polygoni Multiflori 1～150 gram, Radix Adenophorae (Radix Glehniae) 1～150 gram, Fructus Lycii 1～100 gram, Fructus Ligustri Lucidi 1～50 gram, Carapax Trionycis (processed) 1～100 gram, Carapax Et Plastrum Testudinis (processed) 1～100 gram, Herba Pogostemonis 1～100 gram, Fructus Amomi 1～100 gram, Cortex Magnoliae Officinalis 1～100 gram, Fructus Amomi Rotundus 1～100 gram, Fructus Tsaoko 1～50 gram.
Be preferably:
Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Fructus Rosae Laevigatae 20 grams, Herba Cistanches 30 grams, Radix Rehmanniae Preparata 40 grams, Radix Polygoni Multiflori 50 grams, Radix Adenophorae (Radix Glehniae) 30 grams, Fructus Lycii 40 grams, Fructus Ligustri Lucidi 20 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams, Cortex Magnoliae Officinalis 40 grams, Fructus Amomi Rotundus 30 grams, Fructus Tsaoko 10 grams.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.This is the important content of Thailand one and Pu (Beijing) Chinese medicine academy patent strategy.
The structure of Thailand one and Pu patent strategy is convenient to Chinese medicine and is realized standardization, scale, industrialization, modernization and industrialization.For traditional Chinese medicine development has been opened up a road that meets the Chinese medicine self-law with innovation.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the cardiac failure patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
Each raw material of above-mentioned weight is mixed, after decocting for three times, three filtrates is mixed, filter, be concentrated into the concentration of regulation, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating cardiac failure of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 39 routine patients altogether, wherein male 23 examples, women 16 examples; The oldest person 75 years old, the age reckling has only 23 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 6 courses of treatment altogether.
The therapeutic evaluation standard
Cure: lassitude and weak, dyspnea, out of breath, cough uncomfortable in chest, wheezing, the limb edema, distension of jugular vein, inappetence, symptoms such as nausea and vomiting all take a turn for the better, and sign and coherence check index are improved fully, and the patient does not have any bad sensation, and is in high spirits.
Produce effects: lassitude and weak, dyspnea, out of breath, cough uncomfortable in chest, wheezing, the limb edema, distension of jugular vein, inappetence, symptoms such as nausea and vomiting are improved substantially, and sign and coherence check index are improved obviously, and the patient does not have big bad sensation, and spirit is improved.
Effectively: lassitude and weak, dyspnea, out of breath, cough uncomfortable in chest, wheezing, the limb edema, distension of jugular vein, inappetence, symptoms such as nausea and vomiting take a turn for the better to some extent, and sign and coherence check index also have improvement, and the patient is bad to be felt to still have, and spirit is better.
Invalid: sign does not have any change, and symptom such as preceding feels depressed, and lethargy is depressed.
Model case:
1, Lee, woman, 65 years old, retired employees.
Coronary disease medical history 3 years, because of the paroxysmal shirtfront pain of feeling oppressed, two lower limbs edema and being in hospital are diagnosed as the coronary heart disease heart failure before the Spring Festival in 2007.Through Drug therapys such as heart tonifying diuresis blood vessel dilating, lose and be clearly better, initiatively require to spend the Spring Festival at home, at the fifth day of a lunar month night in the first month of the lunar year, preceding card increases the weight of suddenly, invites surplus treatment upon somebody's introduction after the Spring Festival, stuffy pain over the chest, cardiopalmus, orthopnea, can not put down for sleeping inly, it is cool that extremity are felt, cyanosis, two lower limb pitting edemas, body of the tongue purple, tongue neatly, be the Rhizoma Zingiberis tongue, pulse condition is heavy thin.
Take Chinese medicine composition of the present invention after 2 days, feel oppressed, pain, cardiopalmus alleviates, clothes Chinese medicine composition of the present invention 5 days continues, the pain of feeling oppressed is light greatly, can put down the sleep of crouching, and cyanosis takes a turn for the better, extremity have warmness, and edema fades, and it is weak only to feel cardiopalmus, obeyed Chinese medicine composition of the present invention again 15, the pain of feeling oppressed does not have, and cardiopalmus takes a turn for the better, cyanosis does not have, and edema is slight, obeys Chinese medicine composition of the present invention again 2 months, cardiopalmus, edema disappear, and diet increases, and it is happy that the patient quite feels.
2, Lee so-and-so, woman, 71 years old, retired cadre.
The patient feels chest distress pain first before January, and back excuse is swooned, felt suffocated and fall in a swoon once, revives voluntarily after two or three minutes.School's consultation of doctors is diagnosed as heart failure, the hospitalization first quarter moon, and it is more serious to feel suffocated, dysuria, big abdomen and lower limbs edema, pale white complexion is impractical, lip dark purple purple, cold limbs.Arteries and veins closes for right cun and moistens, and is heavy as not having; A left side cun heavy and a little less than, close heavy string puckery and a little less than, two chis are faint, several can not by.
Take Chinese medicine composition of the present invention after 3 days, dizzy, the alleviation of feeling suffocated, breathing and urine are more smooth, continue and obeyed Chinese medicine composition of the present invention 5, breathe and continue to take a turn for the better, lower limb is swollen slightly to disappear, the pain of feeling oppressed is light greatly, and cyanosis takes a turn for the better, and extremity have warmness, obeyed Chinese medicine composition of the present invention again 15, dizzy, feel suffocated, pain do not have, cyanosis does not have, edema is slight, obeys Chinese medicine composition of the present invention again 20, breathes smooth and easy, lower limb is swollen to disappear entirely, and diet increases, and the patient lives normally.
3, Lee so-and-so, woman, 82 years old, peasant.
The patient is tight, the cardiopalmus several years of gas repeatedly, increases the weight of to accompany surplus the hydrosarca 20 day.Poor appetite is felt sick oliguria.Once examined and be coronary heart disease, the atrial fibrillation rhythm of the heart, heart failure.Obey western medicine in recent years, but it is not good enough to obey western medicine result in the recent period always, and takes medicine vomiting is arranged more, gas is tight, cardiopalmus can not be improved, and clothes diuretic edema does not subtract, and invites surplus to its family's diagnosis and treatment then.Patient's spirit is poor, the lazy speech of breathing hard, and whole body severe edema, extremity are not warm, pale complexion, the little purple of lip, light purplish tongue, thin fur is tender, and deep-thready pulse is tied generation.
Take Chinese medicine composition of the present invention after 3 days, urine is increased, and edema is improved, continue and obeyed Chinese medicine composition of the present invention 1 month, edema continues to take a turn for the better, and gas is tight, the disease of cardiopalmus is improved, extremity are temperature gradually, and the disease of feeling sick is also removed, and food is received improvement greatly, spirit is gradually good, obey Chinese medicine composition of the present invention after treatment in 3 months again, breathe smooth and easyly, edema disappears entirely, have rosy cheeks, symptom all disappears.
4, Lee, man, 10 years old.
Viral myocarditis, follow-up make up one's mind decline, hospitalization, heart failure are failed effectively control, after again and again, heart failure is surplus in the of 20 day, the infant lazy speech of breathing hard, fatigue and weakness, indigestion and loss of appetite, it is cold that whole body is felt, body is indentation in quilt, and the tachypnea of panting can not be put down for sleeping in, die Blausucht, lassitude, cardiac monitoring is shown: supraventricular tachycardia, body of the tongue is light red, white and thin fur, deep-thready pulse.
Take Chinese medicine composition of the present invention after 10 days, the tachypnea of panting improves, and can put down for sleeping inly, and clothes Chinese medicine composition of the present invention 1 month continues, cyanosis takes a turn for the better, extremity have warmness, and food is received improvement greatly, and spirit is gradually good, obey Chinese medicine composition of the present invention again after 2 months, cardiac monitoring is shown: normal, breathe smooth and easyly, and the patient fully recovers.
5, grandson so-and-so, man, 62 years old.
Fever and cough is vexed to be breathed heavily with " pneumonia " hospitalization because of flu causes.Through with antibiotic therapies such as penicillin 8 days, the state of an illness day by day increases the weight of on the contrary, and is flushing, 40 ℃ of hyperpyrexia, profuse perspiration, rapid breathing, vexed breathing heavily, dysphoria can not be put down for sleeping in, expectorant sound is filtered, and expectorant is yellow thick and glutinous, thirsty polydipsia, stool day 7～8 times, water sample, stench; oliguria with reddish urine, it is dry and cracked that full and large pulse, red tongue do not have Tianjin dry, rough and yellow fur.
Take Chinese medicine composition of the present invention after 2 days, hot-tempered yearningly decrescence, sweating reduces, breathe heavily gesture and slow, amount of expectoration reduces, hyperpyrexia decline (38.8 ℃), the diarrhoea number of times reduces, and continues and obeys Chinese medicine composition of the present invention 3, and the state of an illness is obviously alleviated, hyperpyrexia moves back (T37.2 ℃), and excessive thirst is separated, big perspiration stopped, diarrhoea is stopped, and dyspnea with rapid and short breath is flat, obeys Chinese medicine composition of the present invention again after 2 months, all diseases are known flat, patient's recovery from illness.
6, Chen, man, 49 years old, cadre.
Recurrent cough, expectoration, tight 2 first quarter moons of gas, symptom aggravation and cardiopalmus, edema 1 month.Hospital gives intramuscular injection and oral chronic bronchitis and infection medicine, does not take effect, and cardiopalmus, edema of pair of lower extremities occur; After multiple inspection is diagnosed as " chronic bronchitis and infect, heart failure ", through antiinflammatory, heart tonifying, diuresis, cough-relieving repeatedly and treatment such as relieving asthma alleviation is arranged, but the time have repeatedly.The patient is uncomfortable in chest, and is indigestion and loss of appetite, die Blausucht, whole body moderate edema, especially with two lower limb for very, two pulmonary respiration sounds are thick, the dried moist rale of audible, electrocardio diagram: sinus rate, atrial hypertrophy, left ventricle high voltage.
Take Chinese medicine composition of the present invention after 7 days, cardiopalmus takes a turn for the better, and gas tightly improves, uncomfortable in chest more easypro, cough slows down, and edema slightly disappears, continue and obeyed Chinese medicine composition of the present invention 15, cyanosis takes a turn for the better, and edema fades, symptom is greatly taken on a new look, obeyed Chinese medicine composition of the present invention again 1 month, patient respiratory is smooth and easy, and edema disappears entirely, diet increases, and electrocardiogram shows normal.
7, Liu so-and-so, woman, 46 years old, teacher.
Cardiopalmus, breathe hard, cough with asthma, edema of lower limbs two months, increase the weight of a week, emaciated physique, it is weak to lose heart, greenish complexion is dark, the tone is humble, and cardiopalmus is breathed hard, edema of lower limbs, the cough with asthma phlegm retention is rare in vain, feels sick dizziness, abdominal distention, indigestion and loss of appetite, big dry stool, the urine frequency, night, irritated the perspiration was difficult for sleep, usually health still can, easy catching a cold, extremity are cold, aversion to cold, a little less than left and right sides floating-rolling pulse string is slow, restrain unevenly, the light tongue of body of the tongue slight of stature neatly is rotten slightly in vain greasy, skewness.Hospital looks into and controls: through rabat, electrocardio, blood, uroscopy, be diagnosed as heart failure and merge pulmonary infection, use a Zhou Buxiao such as " cedilanid, butylamine Ka Na " treatment, satisfy and examine.
Take Chinese medicine composition of the present invention after 7 days, cardiopalmus takes a turn for the better, and the improvement of breathing hard is felt sick and ended, cough with asthma slows down, and edema slightly disappears, and after 10 days, edema continues to disappear continue clothes Chinese medicine composition of the present invention, abdominal distention alleviates, and appetite increases, and continues and obeys Chinese medicine composition of the present invention 15, and complexion takes a turn for the better, edema is slight, and sleep improves, and two is just normal, and symptom is greatly taken on a new look, obey Chinese medicine composition of the present invention again after 3 months, the patient has rosy cheeks, and edema disappears entirely, breathe smooth and easyly, brace up, all normal.
8, Pan so-and-so, male, 37 years old, workman.
Patient's chronic cardiopulmonary disease heart failure, heart failure increases the weight of based on right heart failure two months ago.After treating January, western modern medicine alleviates, but the patient does not follow the doctor's advice and takes medicine and strengthen the activity heart failure voluntarily and further increase the weight of again, hydrosarca, abdominal distention are very, die Blausucht, finger tip is livid purple, inappetence, weak can not the walking, moving then breathe heavily speed, the row western medical treatment did not have and is clearly better in nearly 20 days, and edema further increases the weight of on the contrary.
Take Chinese medicine composition of the present invention after 7 days, edema, abdominal distention slightly disappear, but small number of activity, after 10 days, cyanosis takes a turn for the better continue clothes Chinese medicine composition of the present invention, and edema continues to disappear, abdominal distention alleviates, and appetite increases, and continues and obeys Chinese medicine composition of the present invention 15, edema is slight, and spirit is gradually shaken, and symptom is greatly taken on a new look, can do suitable housework, obey Chinese medicine composition of the present invention again 2 months, edema disappears entirely, brace up, resume work.
Five, therapeutic outcome:
In the 39 routine cases of being accepted for medical treatment,, wherein cure 18 examples through treatment in 6 months, produce effects 13 examples, effective 7 examples, invalid 1 example, total effective rate reaches 97%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment cardiac failure patient.
Claims (3)
1. Chinese medicine composition for the treatment of cardiac failure is characterized in that: be made up of following bulk drugs:
Radix Puerariae 100 grams, Pericarpium Citri Reticulatae 100 grams, Pericarpium Citri Reticulatae Viride 30 grams, Fructus Aurantii Immaturus 50 grams, the Radix Aucklandiae 40 grams, Rhizoma Cyperi 100 grams, Fructus Toosendan 50 grams, Aspongopus 30 grams, Flos Caryophylli 15 grams, Pericarpium Zanthoxyli 15 grams, Cortex cinnamomi japonici (Ramulus Cinnamomi) 20 grams, the Radix Linderae 50 grams, Lignum Aquilariae Resinatum 15 grams, Lignum Santali Albi 20 grams, Herba Lysimachiae foenum-graeci 20 grams, Benzoinum 30 grams, Cortex Cinnamomi 20 grams, Fructus Evodiae 30 grams, Rhizoma Alpiniae Officinarum 30 grams, Rhizoma Chuanxiong 40 grams, Rhizoma Corydalis 50 grams, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 60 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 50 grams, Radix Achyranthis Bidentatae 20 grams, rhizoma sparganic 15 grams, Rhizoma Curcumae 15 grams, Squama Manis (processed) 20 grams, Radix Ginseng 15 grams, Radix Panacis Quinquefolii 10 grams, Radix Astragali 100 grams, Radix Codonopsis 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Dioscoreae 50 grams, Radix Angelicae Sinensis 50 grams, Styrax 30 grams, Venenum Bufonis 10 grams, Rhizoma Acori Graminei 50 grams, Borneolum Syntheticum 10 grams, Camphora 15 grams, Moschus 1 gram, Cordyceps 20 grams, Fructus Lycii 40 grams, Carapax Trionycis (processed) 30 grams, Carapax Et Plastrum Testudinis (processed) 30 grams, Herba Pogostemonis 30 grams, Fructus Amomi 20 grams.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: described Chinese medicine composition is prepared into pill, capsule, tablet, granule or oral liquid.
3. the application of any described Chinese medicine composition of claim 1～2 in preparation treatment cardiac failure medicine.
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| CN101972446B (en) * | 2010-08-26 | 2011-10-12 | 葛德钜 | Medicament for treating coronary disease and preparation method thereof |
| CN102397521B (en) * | 2011-11-23 | 2014-04-09 | 王凤荣 | Tradtional Chinese medicine plaster for preventing and treating stenocardia and preparation method thereof |
| CN102579972B (en) * | 2011-12-05 | 2013-07-10 | 北京工商大学 | Traditional Chinese medicine composition and preparation with effect of relieving dark eye circles and preparation method of traditional Chinese medicine composition and preparation |
| CN102920864B (en) * | 2012-09-14 | 2015-06-17 | 孟宪周 | Chinese medicament for treating cerebrovascular diseases |
| CN103495139B (en) * | 2013-10-11 | 2015-08-05 | 陈国军 | One treats cardiopathic Chinese medicine composition |
| CN103656100B (en) * | 2013-12-09 | 2016-08-17 | 南阳医学高等专科学校 | A kind of Chinese herbal medicine treating myocardial ischemia |
| CN103892371B (en) * | 2014-03-12 | 2015-06-17 | 安徽金鹰农业科技有限公司 | Grape and soft-shelled turtle soup powder and preparation method thereof |
| CN106214835A (en) * | 2016-08-26 | 2016-12-14 | 吕晶晶 | A kind of Chinese medicine composition treating heart failure and preparation method thereof |
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| CN101332231A (en) * | 2007-06-25 | 2008-12-31 | 辽宁中医药大学附属医院 | Medicine for treating heart failure |
| CN101524469A (en) * | 2009-04-17 | 2009-09-09 | 山东大学齐鲁医院 | Chinese herbal medicine compound preparation for treating congestive heart failure and preparation method thereof |
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| CN101332231A (en) * | 2007-06-25 | 2008-12-31 | 辽宁中医药大学附属医院 | Medicine for treating heart failure |
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