CN1085083C - Prescription and production method of medicine to cure stenocardia-type coronary heart disease - Google Patents
Prescription and production method of medicine to cure stenocardia-type coronary heart disease Download PDFInfo
- Publication number
- CN1085083C CN1085083C CN93101424A CN93101424A CN1085083C CN 1085083 C CN1085083 C CN 1085083C CN 93101424 A CN93101424 A CN 93101424A CN 93101424 A CN93101424 A CN 93101424A CN 1085083 C CN1085083 C CN 1085083C
- Authority
- CN
- China
- Prior art keywords
- radix
- medicine
- root
- heart disease
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a medicinal formula of a medicament for treating coronary disease, particularly angina pectoris type coronary disease, and a production method thereof. After Chinese eaglewood wood, rosewood and styrax are crushed into fine powder, the fine powder is added to medicinal liquid obtained by decocting astragalus root, ginseng, notoginseng, haw, cassia occidentalis semen cassiae torae, fleeceflower root, ganoderma, cattail pollen, safflower, kudzuvine root, seaweed, red sage root, hemlock parsley, finger citron, prepared nutgrass galingale rhizome, ophiopogon root, rhizoma corydalis, Chinese box twig and other traditional Chinese medicine in water; the fine powder is uniformly mixed with the traditional Chinese medicine, and then, the mixture is granulated and dried. Checking and clinical application of the prepared medicine indicate that the prepared medicine has the advantages of better curative effect than that of other traditional Chinese medicine and western medicine, no toxic or side effect, good short-term curative effect and long-term curative effect and reasonable formula. The prepared medicine conforms to traditional Chinese medicine theory.
Description
The present invention relates to a kind ofly to treat coronary heart disease, particularly angina pectoris coronary heart disease, all with the prescription and the production method of the medicine of Chinese medicine preparation.
Coronary atherosclerotic heart disease is called for short coronary heart disease, and the sickness rate in total population is 7～9%, and is then higher person in middle and old age, is the main cause that causes sudden death clinically.Before the present invention occurs, the Chinese medicine and western medicine of treatment coronary heart disease has: sorbitrate, nifedipine, trinitin sheet, persantin, second be flushed with drink iodine skin ketone, diltiazem, slow heart rate, the live heart, SUXIAO JIUXIN WAN, FUFANG DANSHEN PIAN, XIONGDAN JIUXINWAN, storax pill for treating coronary heart disease, NAOXINSHU etc., these medicines are because of all being to pass through blood vessel dilating on pharmacology, temporarily solve the blood supply problem, so short term efficacy is in various degree all arranged, but there is not late result, do not reach the purpose of healing at all, and take drug resistance and the side effect generation that all has in various degree for a long time.This shows that its production method, particularly drug formulation remain further to be studied.
The prescription and the production method that the purpose of this invention is to provide a kind of novel medicine, the medicine of producing according to this method has late result again, and finally reaches the healing purpose the existing short term effect of the treatment of coronary heart disease, and generation without any side effects.
The present invention is the new pharmacological action that the qi-blood relationship theory learned according to Chinese traditional medicine and modern medicine are found various institutes of Chinese materia medica, according to " principle of strengthening vital QI to eliminate pathogenic factors ＂ is finished for symptomatic treatment in acute condition; radical treatment in chronic case; set upright based on reinforcing; ｀ lead to ' just must not hinder; ｀ mend ' must not be detained, giving consideration to both the incidental and fundamental.
Chinese medicine is thought: the pathogenesis of coronary heart disease generation, many owing to worn with age, deficiency of kidney-QI, and kidney is people's a Yuanyang Kidney-Yin, so further developing, pectoral qi void can cause also void of kidney yang, further develop again and can cause also void of kidney yin, cause kidney Yuanyang Kidney-Yin two to lose intemperance of taking food, impairing the spleen and stomach, cause deficiency-weakness of spleen-QI, the biochemical general source of pectoral qi, water is wet to be lost in fortuneization, turbid damp is detained in the heart, internal injury caused by excess of seven emotions, qi depression to blood stasis, because of insufficiency of pectoral QI to pass through heart arteries and veins promoting the circulation of blood gas, and the hyperamization row is unfavorable, even blood-stasis internal-depression is pondered over overstrain, injure heart spleen.The traditional Chinese medical science is thought: gas and blood are human body two big important substance and energy foundations, the ＂ qi being the governor of blood, blood being the material foundation of QI ＂, the normal operation of blood can promote the function of the vital organs of the human body to run well, be obstructed for some reason in passages through which vital energy circulates as QI and blood, just cause ＂ stagnation of QI and blood may bring about pain ＂, just occur anginal symptom clinically.Modern medicine study proves: Radix Ginseng still can be regulated the central nervous system except that having function such as reinforce functional activities of the heart, improves people's mentality and physical function, resisting fatigue and calmness; Adjust hormonal system and function of immune system; Promote positive nitrogen balance, promote the dawn white matter synthetic, blood pressure lowering and blood fat; The heart tonifying coronary dilating strengthens coronary flow and myocardial oxygen delivery.Radix Ginseng contains the trace element of abundant needed by human.The Radix Astragali can strengthen myocardial contraction, improves cardiac function, and arrhythmia improves blood flow, mediation microcirculation protection arterial endothelial cell.Fructus Crataegi, Radix Salviae Miltiorrhizae, Flos Carthami, Radix Notoginseng, Semen Cassiae, Radix Polygoni Multiflori, Ganoderma etc. have blood circulation promoting and blood stasis dispelling to improve high blood coagulation state, significantly improve hemorheological property, reduce blood viscosity, microcirculation improvement, improve internal organs amount of blood supply and body's immunity, allevating angina pectoris and blood pressure lowering, blood fat reducing etc.Radix Salviae Miltiorrhizae still has the function of protection cardiac muscle; Rhizoma Chuanxiong has a surname that invigorates blood circulation promote blood circulation network, resolving depression, the chest stuffiness relieving, wind-expelling pain-stopping, effect such as regulate the flow of vital energy, and also expansible coronary artery and cerebrovascular improve cardiac muscle and cerebral ischemia, and antithrombotic formation improves high blood coagulation state etc.The Styrax dirty pain relieving of having one's ideas straightened out brokenly.Radix Paeoniae Rubra energy clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, pain relieving.Radix Trichosanthis can clearing away heat and promoting production of body fluid, quench the thirst.Lignum Aquilariae Resinatum can promoting the circulation of QI to relieve pain.Rhizoma Corydalis, Ramulus Buxi Sinicae, Lignum Dalbergiae Odoriferae can circulation of qi promoting, invigorate blood circulation, pain relieving.Radix Notoginseng, Semen Cassiae, Flos Carthami, Pollen Typhae, Radix Puerariae, Sargassum, Fructus Citri Sarcodactylis, Rhizoma Cyperi (system), Radix Ophiopogonis etc. have coronary blood flow increasing, and decreased heart rate reduces myocardial oxygen consumption, improves myocardial oxygen delivery, functions such as blood fat reducing, blood glucose.
The present invention realizes as follows.
At first select medicine by following prescription:
Radix Astragali 800-1400g Radix Notoginseng 300-700g
Radix Ginseng 200-400g Fructus Crataegi 1000-2000g
Semen Cassiae 400-450g Radix Polygoni Multiflori 400-450g
Ganoderma 200-250g Pollen Typhae 300-450g
Flos Carthami 300-450g Radix Puerariae 600-850g
Sargassum 300-450g Radix Salviae Miltiorrhizae 400-650g
Rhizoma Chuanxiong 300-450g Fructus Citri Sarcodactylis 400-450g
Rhizoma Cyperi (system) 500-650g 400-450g Radix Ophiopogonis
Rhizoma Corydalis 400-450g Lignum Aquilariae Resinatum 200-350g
Lignum Dalbergiae Odoriferae 200-450g Styrax 200-450g
Ramulus Buxi Sinicae 400-850g
17 flavor Chinese medicines such as the Radix Astragali in the above-mentioned prescription, Radix Notoginseng, Radix Ginseng, Fructus Crataegi, Semen Cassiae, Radix Polygoni Multiflori, Ganoderma, Pollen Typhae, Flos Carthami, Radix Puerariae, Sargassum, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Citri Sarcodactylis, Rhizoma Cyperi (system), Radix Ophiopogonis, Rhizoma Corydalis are decocted with water, filtration back adding 95% ethanol in spissated medicinal liquid makes it to contain the alcohol amount and reaches 60%, the post precipitation recovered alcohol, in spissated medicinal liquid, add fine powder and the mixing that is ground into by Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae, Styrax, make the graininess oven dry, incapsulate promptly after granule is sieved.
Domestic and international by retrieval no same or analogous prescription and production method.
Embodiment:
(1) gets Radix Astragali 1200g, Radix Notoginseng, each 440g of Radix Ginseng, Fructus Crataegi 1200g, Semen Cassiae, Radix Polygoni Multiflori, Pollen Typhae, Flos Carthami, Sargassum, Rhizoma Chuanxiong, Fructus Citri Sarcodactylis, Radix Ophiopogonis, each 420g of Rhizoma Corydalis, Ganoderma 220g, Radix Puerariae, Radix Salviae Miltiorrhizae, each 600g of Rhizoma Cyperi (processed) add water 25000ml with this 17 flavor Chinese medicine and decocted 3 hours in a container, decoct the postpone that cools, got medicinal residues 1 and medicinal liquid 1 after filtration.(2) medicinal residues 1 and water 15000ml were decocted 2 hours in same container, cool postpone filter medicinal residues 2 and medicinal liquid 2.(3) medicinal residues 2 and water 10000ml were decocted 1.5 hours in same container, cool postpone is filtered, and gets medicinal residues 3 and medicinal liquid 3.(4) medicinal liquid 1, medicinal liquid 2, medicinal liquid 3 are merged.(5) medicinal liquid is concentrated into the thick paste shape.(6) in medicinal liquid, add 95% ethanol, make it to contain the alcohol amount and reach 60%.(7) 24 hours recovered alcohols of precipitation.(8) get Lignum Aquilariae Resinatum 220g, Lignum Dalbergiae Odoriferae 420g, Styrax 420g powder becomes fine powder to add mixing in the spissated medicinal liquid.(9) granulate.(10) the medicine grain is dried.(11) the medicine grain is sieved after, the capsule of packing into No. 0.
The gained medicine is through testing identity as stated above, and the medicine stable performance through animal experiment proof avirulence, can be eliminated the atheromatous plaque of White Rabbit aorta formation.The suffered Shaanxi Province of Xi'an traditional Chinese medical science multidisciplinary research Department of Public Health of the Second Artillery Force entrusts, the diagnostic criteria for coronary heart disease of drafting according to International Society of Cardiology in 1979 and cooperative association and World Health Organization's naming standard associating special topic group, stochastic sampling 100 routine angina pectoris coronary heart disease examples, carry out the curative effect contrast observing from year February in January, 1989 to 1992, proof not only has good short term effect by the medicine of prescription provided by the present invention and production technology manufacturing, and good late result arranged, contrast through patient, good social benefit is arranged with other medicine of clothes.
Claims (2)
1, a kind of SHANHAI PILL for the treatment of angina pectoris coronary heart disease is made up of multiple flavour of a drug, it is characterized in that: each pass of measuring between the medicine of distinguishing the flavor of is:
Radix Astragali 800-1400g Radix Notoginseng 300-700g
Radix Ginseng 200-400g Fructus Crataegi 1000-2000g
Semen Cassiae 400-450g Radix Polygoni Multiflori 400-450g
Ganoderma 200-250g Pollen Typhae 300-450g
Flos Carthami 300-450g Radix Puerariae 600-850g
Sargassum 300-450g Radix Salviae Miltiorrhizae 400-650g
Rhizoma Chuanxiong 300-450g Fructus Citri Sarcodactylis 400-450g
Rhizoma Cyperi (processed) 500-650g 400-450g Radix Ophiopogonis
Rhizoma Corydalis 400-450g Lignum Aquilariae Resinatum 200-350g
Lignum Dalbergiae Odoriferae 200-450g Styrax 200-450g
Ramulus Buxi Sinicae 400-850g
2, a kind of preparation technology of SHANHAI PILL of treatment angina pectoris coronary heart disease according to claim 1, it is characterized in that: with the Radix Astragali, Radix Notoginseng, Radix Ginseng, Fructus Crataegi, Semen Cassiae, Radix Polygoni Multiflori, Ganoderma, Pollen Typhae, Flos Carthami, Radix Puerariae, Sargassum, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Fructus Citri Sarcodactylis, Rhizoma Cyperi (processed), Radix Ophiopogonis, Rhizoma Corydalis 17 flavor Chinese medicines decoct with water, filter the back and in spissated medicinal liquid, add 95% ethanol, make it to contain the alcohol amount and reach 60%, the post precipitation recovered alcohol, in spissated medicinal liquid, add by Lignum Aquilariae Resinatum, Lignum Dalbergiae Odoriferae, fine powder that Styrax is ground into and mixing, make the graininess oven dry, get final product after incapsulating after granule is sieved.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101424A CN1085083C (en) | 1993-02-17 | 1993-02-17 | Prescription and production method of medicine to cure stenocardia-type coronary heart disease |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93101424A CN1085083C (en) | 1993-02-17 | 1993-02-17 | Prescription and production method of medicine to cure stenocardia-type coronary heart disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1081890A CN1081890A (en) | 1994-02-16 |
| CN1085083C true CN1085083C (en) | 2002-05-22 |
Family
ID=4983584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93101424A Expired - Lifetime CN1085083C (en) | 1993-02-17 | 1993-02-17 | Prescription and production method of medicine to cure stenocardia-type coronary heart disease |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1085083C (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1072908C (en) * | 1999-09-07 | 2001-10-17 | 朱长征 | Food additive benefiting patients of diabetics, coronary heart disease and tumor and its preparing method |
| CN100339085C (en) * | 2003-09-23 | 2007-09-26 | 天津天士力制药股份有限公司 | Combination of Chinese traditional medicine for curing cardiovascular and cerebrovascular diseases |
| CN1305508C (en) * | 2005-10-17 | 2007-03-21 | 高春 | Pill for treating coronary heart disease |
| CN101199678B (en) * | 2006-12-15 | 2012-01-04 | 上海中医药大学附属曙光医院 | Chinese medicine agent for treating CHF heart failure merger angina and preparing method thereof |
| CN101843645B (en) * | 2009-11-18 | 2011-07-20 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating tachycardia |
| CN102526189B (en) * | 2012-02-20 | 2013-08-07 | 崔新明 | Chinese medicinal composition for treating angina pectoris |
| CN105125857A (en) * | 2015-10-09 | 2015-12-09 | 宋振民 | Tablets for treating angina pectoris coronary disease and preparing method thereof |
| CN110339326A (en) * | 2019-08-29 | 2019-10-18 | 朱江 | A kind of logical heart ball of stilbene deer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030183A (en) * | 1987-06-30 | 1989-01-11 | 马德林 | A kind of manufacture method of preventing and treating the coronary heart disease medicine for external use |
| CN1052429A (en) * | 1990-09-15 | 1991-06-26 | 刘绍文 | The prescription of QIANGXIN JIANNAO YE, making |
-
1993
- 1993-02-17 CN CN93101424A patent/CN1085083C/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030183A (en) * | 1987-06-30 | 1989-01-11 | 马德林 | A kind of manufacture method of preventing and treating the coronary heart disease medicine for external use |
| CN1052429A (en) * | 1990-09-15 | 1991-06-26 | 刘绍文 | The prescription of QIANGXIN JIANNAO YE, making |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1081890A (en) | 1994-02-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101181600B (en) | Traditional Chinese medicine composition for curing cardiovascular and cerebrovascular diseases | |
| CN1169541C (en) | Medicine for treating rheumatoid arthritis | |
| CN1224614A (en) | Medicine for preventing and curing cardiac and cerebral vascular diseases and its preparation | |
| CN1305483C (en) | Heart failure regulating Chinese medicine | |
| CN104127699A (en) | Vitality-tonifying health-preserving preparation and preparation method thereof | |
| CN1085083C (en) | Prescription and production method of medicine to cure stenocardia-type coronary heart disease | |
| CN101433689A (en) | Kudzu root and longstamen onion bulb oral liquid and preparation method | |
| CN103285142A (en) | Traditional Chinese medicine formula for improving brain functions and treating encephalatrophy | |
| CN101700336B (en) | Chinese herba preparation for curing craniocerebra trauma residual headache and preparation method | |
| CN1085082C (en) | Recipe of Fumailing for curing arrhythmic coronary heart disease and producing method | |
| CN105920546A (en) | Soft-liver spleen-shrinking traditional Chinese medicine composition for treating hepatitis B liver cirrhosis | |
| CN1181850C (en) | Chinese medicinal preparation for treating cadiovascular and cerebrovascular diseases | |
| CN105796845A (en) | Application of medicine composition in preparing medicine for treating female climacteric syndromes | |
| CN115252753A (en) | Traditional Chinese medicine composition for treating insomnia and application thereof | |
| CN107998282A (en) | A kind of Chinese medicine for strengthening immune, nti-freckle, preventing the proliferation of mammary gland and preparation method thereof | |
| CN1028003C (en) | Method of preparing medicine for treatment of coronary heart disease | |
| CN104524479B (en) | A kind of Chinese medicine composition for treating premenstrual syndrome and preparation method thereof | |
| CN102091300B (en) | Granule for protecting liver and relieving depression | |
| CN105902897A (en) | Pharmaceutical preparation for treating pancreatic cancer and application thereof | |
| CN100490787C (en) | Capsule for treating heart palpitation | |
| CN105749216A (en) | Traditional Chinese medicine wine for treating hypertension and preparation method thereof | |
| CN101703660B (en) | Anti-aging medicament | |
| CN101199667A (en) | Chinese medicine for treating leukemia, aplastic anemia | |
| CN101181516B (en) | Chinese medicine prescription orally taken for curing leukaemia | |
| CN105560911B (en) | A kind of Chinese medicine and preparation method thereof for treating hypertension |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C53 | Correction of patent for invention or patent application | ||
| CB02 | Change of applicant information |
Applicant after: Xi'an Tranditional Chinese Medicine Multi-discripline Institute, Sanhaidan Enter Applicant before: PLA Second Artillery Xi'an Institute of traditional Chinese Medicine |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: CHINESE PLA SECOND ARTILLERY CORPS, XI AN INSTITUTE OF MULTIDISCIPLINARY HERBALIST DOCTOR TO: SHANHAIDAN ENTERPRISES GROUP, XI AN INSTITUTE OF MULTIDISCIPLINARY HERBALIST DOCTOR |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| PP01 | Preservation of patent right |
Effective date of registration: 20090311 Pledge (preservation): Preservation |
|
| PD01 | Discharge of preservation of patent |
Date of cancellation: 20090911 Pledge (preservation): Preservation registration |
|
| C17 | Cessation of patent right | ||
| CX01 | Expiry of patent term |
Expiration termination date: 20130217 Granted publication date: 20020522 |