CN1263502C

CN1263502C - Chinese traditional medicine for treating hypertension

Info

Publication number: CN1263502C
Application number: CN 200410040124
Authority: CN
Inventors: 曹琼
Original assignee: Individual
Current assignee: Individual
Priority date: 2004-06-30
Filing date: 2004-06-30
Publication date: 2006-07-12
Anticipated expiration: 2024-06-30
Also published as: CN1593571A

Abstract

The present invention discloses a Chinese medicine for treating high blood pressure, which is prepared from virgate wormwood herb, mongolian snakegourd, haw, flos chrysanthemi, rhynohophylla, semen cassiae torae, tribulus terrestris, motherwort herb, curcuma longa, cattail pollen, flower of japanese banana, membranous milkvetch root, chuanxiong rhizome, gold theragran, Chinese taxillus twig, eucommia bark, white peony root, radix achyranthis bidentatae, common st. paulswort, caulis piperis kadsurae, earthworm, radish seed, herba plantaginis, ginkgo leaf, ground beetle, notoginseng and chrysanthemum. The present invention has the main effects of promoting diuresis, resolving phlegm, promoting qi to activate blood, nourishing yin for suppressing hyperactive yang, nourishing and benifiting the liver and the kidney, eliminating dampness and dredging channels by adopting a method of lowering blood pressure, relieving risk factors and protecting organs, namely trinity combined treatment, and has the effects of lowering and stabilizing blood pressure, improving blood viscosity and improving microcirculation flow rate when used to treat high blood pressure.

Description

The hypertensive Chinese medicine of a kind of treatment

Technical field: the present invention relates to the hypertensive medicine of a kind of treatment, the hypertensive Chinese medicine of particularly a kind of treatment belongs to field of traditional Chinese.

Background technology: hypertension is a kind of commonly encountered diseases, frequently-occurring disease, and effectively the hypertensive pharmaceutical progress of control is very fast at present, and a kind of novel nitrite (nitrogen oxide NO) can improve trunk elasticity, but resistance vessel is not had influence; Start genetic therapy, at the oligonucleotide relevant with antisense gene viral vector delivery system with blood pressure lowering efficient gene target, hybridization contract the blood vessel gene " make and fall effect " though not talkative radical cure, can it is rapid-action to change present depressor, also fast drawback lost efficacy; Domestic having developed effected a radical cure hypertensive Chinese herbal medicine " voltage stabilizing spirit ", but because drug resource is limited, far can not meet the need of market; " reverse " reinvented in the atherosis and resistance vessel of the blood pressure lowering-blood vessel of doing one's utmost to advocate according to internal authority mechanism; correct body dysequilibrium and protection internal organs " Trinity " and control policy and the limitation and the imperfection of Western medicine, thereby develop the hypertensive natural drug of safe and effective radical cure and become domestic and international mainstream development direction.

Summary of the invention: the object of the present invention is to provide a kind of dampness removing to reduce phlegm, promoting flow of QI and blood, nourishing YIN for suppressing the hyperactive YANG, the liver and the kidney tonifying, eliminating blood stasis and smoothing collaterals, lowering and stabilizing blood pressure effects a radical cure hypertensive pure oral medicinal herb medicine.

The present invention is achieved in that raw material consists of: Herba Artemisiae Scopariae 4.5-60g, Fructus Trichosanthis (Fructus Trichosanthis) 4.5-60g, Fructus Crataegi 6-60g, Flos Chrysanthemi Indici 4.5-35g, Ramulus Uncariae Cum Uncis (Ramulus Uncariae Cum Uncis) 6-35g, Semen Cassiae 6-60g, Fructus Atriplicis Sibiricae (Fructus Atriplicis Sibiricae) 6-35g, Herba Leonuri 5-50g, Rhizoma Curcumae Longae 6-30g, Pollen Typhae 6-30g, Flos Musae 10-100g, Radix Astragali 6-30g, Rhizoma Chuanxiong 6-15g, Radix Polygoni Multiflori (Radix Polygoni Multiflori) 6-50g, Herba Taxilli 6-30g, Cortex Eucommiae 6-30g, Radix Paeoniae Alba 10-30g, Radix Achyranthis Bidentatae (Huaihe River Niu Xi) 6-30g, Herba Siegesbeckiae (Herba Siegesbeckiae) 4.5-30g, Caulis Piperis Kadsurae 4.5-15g, Pheretima 4.5-15g, Semen Raphani 4.5-30g, Herba Plantaginis 4.5-25g, Folium Ginkgo 4.5-20g, ground beetle 1.5-9g, Radix Notoginseng 1.5-6g, Flos Chrysanthemi 4-10g.

The present invention compared with prior art has following advantage:

1, the present invention is with blood pressure lowering, the factor of clearing, and the protection internal organs are Trinitarian Comprehensive Treatment, and main dampness removing reduces phlegm, promoting flow of QI and blood, and nourishing YIN for suppressing the hyperactive YANG is mended the Liver and kidney that overflows, treatment of arthritis and promoting collateral and channels, A distinction should be made between what is primary and what is secondary in the side, Each performs its own functions.

2, hypertension therapy of the present invention has lowering and stabilizing blood pressure, improves blood viscosity, the microcirculation improvement flow improves the blood vessel wall lipid metabolism, atherosclerosis, increase the cardiovascular and cerebrovascular vessel flow, reduce the incidence rate of apoplexy and cardiovascular event, reduce cardiovascular mortality and disability rate.

3, medicine of the present invention is in treatment, lowering and stabilizing blood pressure, and T-CHOL, triglyceride, LDL-C descend clinical verification, effective percentage 93.2%.

4, medicine of the present invention is through pharmacological evaluation, has blood pressure lowering, blood fat reducing, improves the elasticity of blood vessel wall, reduces glutamate pyruvate transaminase.

With this side treatment essential hypertension 103 examples, male's 69 examples account for 67%, and women's 34 examples account for 33%, minimum 29 years old of age, and maximum 73 years old, 29-40 year wherein, 31 examples, 41-50 year, 51 examples were greater than 60 years old person's 21 example; Family history 30 examples are arranged, account for 29%, person's 42 examples that have habits of smoking and alcohol drinking; Differentiation of symptoms and signs for classification of syndrome, type of deficiency of YIN leading to hyper activity of YANG 71 examples account for 68.9%, and the hepatic and renal YIN deficiency 26 examples account for 25.2%, and heart-Yin deficiency type 4 examples account for 3.9%, and deficiency of both YIN and YANG type 2 examples account for 1.9%; Modern medicine typing (according to coronary heart disease hypertension census prevention forum criteria in 1972) hypertension I phases 26 example, II phases 72 example, III phases 5 example, more than the decline of the produce effects diastole as a result 2.7Kpa, obvious 54 examples of doing well,improving, effectively more than the diastolic pressure decline 1.5Kpa, symptom is partly improved 42 examples, invalid 7 examples, total effective rate 93.2%.

Model case: Lee * *, man, 40 years old, the Li nationality, industrial and commercial work, people from Guizhou, disease shows as dizziness, headache, uncomfortable in chest more than 3 years, have a liking for tobacco and wine, hypertension history 4 years, blood pressure 24/16Kpa, the highest 25.5/17Kpa of blood pressure, look into yellowish fur, red tongue, the arteries and veins flood is sliding, be diagnosed as essential hypertension, hyperlipidemia, dialectical genus excessive rising of liver-YANG is thrown this side's treatment, the blood pressure in 4 weeks is reduced to 17/12Kpa, headache, symptom such as dizzy, uncomfortable in chest are removed, and existing blood pressure stabilization recurred at 17/11Kpa in 2002 so far.

The specific embodiment:

Embodiment 1: take by weighing Herba Artemisiae Scopariae 4.5g, Fructus Trichosanthis (Fructus Trichosanthis) 4.5g, Fructus Crataegi 6g, Flos Chrysanthemi Indici 4.5g, Ramulus Uncariae Cum Uncis (Ramulus Uncariae Cum Uncis) 6g, Semen Cassiae 6g, Fructus Atriplicis Sibiricae (Fructus Atriplicis Sibiricae) 6g, Herba Leonuri 5g, Rhizoma Curcumae Longae 6g, Pollen Typhae 6g, Flos Musae 10g, Radix Astragali 6g, Rhizoma Chuanxiong 6g, Radix Polygoni Multiflori (Radix Polygoni Multiflori) 6g, Herba Taxilli 6g, Cortex Eucommiae 6g, Radix Paeoniae Alba 10g, Radix Achyranthis Bidentatae (Huaihe River Niu Xi) 6g; Herba Siegesbeckiae (Herba Siegesbeckiae) 4.5g, Caulis Piperis Kadsurae 4.5g, Pheretima 4.5g, Semen Raphani 4.5g, Herba Plantaginis 4.5g, Folium Ginkgo 4.5g, ground beetle 1.5g, Radix Notoginseng 1.5g, Flos Chrysanthemi 4g cleans standby, Flos Chrysanthemi Indici, Flos Chrysanthemi adds twice of 50% ethanol extraction, add for the first time 6 times of amount ethanol, add for the second time twice of 3 times of amount ethanol extraction, each 1 hour, filter, merging filtrate, reclaim ethanol, be condensed into density and be 1.1 clear paste, standby; All the other medical materials decoct with water twice, add for the first time 10 times of water gagings, add for the second time 8 times of water gagings, decocting 1.5 hours below 100 ℃, filter, merging filtrate, be concentrated into the extractum of relative density 1.3 (80 ℃), clear paste, extractum are merged, 80 ℃ of dryings or spray drying, be ground into fine powder and cross 60 mesh sieves, the conventional operation of process is directly or indirectly made any in granule, capsule, the tablet.

Embodiment 2: take by weighing Herba Artemisiae Scopariae 60g, Fructus Trichosanthis (Fructus Trichosanthis) 60g, Fructus Crataegi 60g, Flos Chrysanthemi Indici 35g, Ramulus Uncariae Cum Uncis (Ramulus Uncariae Cum Uncis) 35g, Semen Cassiae 60g, Fructus Atriplicis Sibiricae (Fructus Atriplicis Sibiricae) 35g, Herba Leonuri 50g, Rhizoma Curcumae Longae 30g, Pollen Typhae 30g, Flos Musae 100g, Radix Astragali 30g, Rhizoma Chuanxiong 15g, Radix Polygoni Multiflori (Radix Polygoni Multiflori) 50g, Herba Taxilli 30g, Cortex Eucommiae 30g, Radix Paeoniae Alba 30g, Radix Achyranthis Bidentatae (Huaihe River Niu Xi) 30g; Herba Siegesbeckiae (Herba Siegesbeckiae) 30g, Caulis Piperis Kadsurae 15g, Pheretima 15g, Semen Raphani 30g, Herba Plantaginis 25g, Folium Ginkgo 20g, ground beetle 9g, Radix Notoginseng 6g, Flos Chrysanthemi 10g cleans standby, Flos Chrysanthemi Indici, Flos Chrysanthemi adds twice of 50% ethanol extraction, add for the first time 6 times of amount ethanol, add for the second time twice of 3 times of amount ethanol extraction, each 1 hour, filter, merging filtrate, reclaim ethanol, be condensed into density and be 1.1 clear paste, standby; All the other medical materials decoct with water twice, add for the first time 10 times of water gagings, add for the second time 8 times of water gagings, decocting 1.5 hours below 100 ℃, filter, merging filtrate, be concentrated into the extractum of relative density 1.3 (80 ℃), clear paste, extractum are merged, 80 ℃ of dryings or spray drying, be ground into fine powder and cross 60 mesh sieves, the conventional operation of process is directly or indirectly made any in granule, capsule, the tablet.

Claims

1, the hypertensive Chinese medicine composition of a kind of treatment, it is characterized in that: raw material consists of: Herba Artemisiae Scopariae 4.5-60g, Fructus Trichosanthis 4.5-60g, Fructus Crataegi 6-60g, Flos Chrysanthemi Indici 4.5-35g, Ramulus Uncariae Cum Uncis 6-35g, Semen Cassiae 6-60g, Fructus Atriplicis Sibiricae 6-35g, Herba Leonuri 5-50g, Rhizoma Curcumae Longae 6-30g, Pollen Typhae 6-30g, Flos Musae 10-100g, Radix Astragali 6-30g, Rhizoma Chuanxiong 6-15g, Radix Polygoni Multiflori 6-50g, Herba Taxilli 6-30g, Cortex Eucommiae 6-30g, Radix Paeoniae Alba 10-30g, Radix Achyranthis Bidentatae 6-30g Herba Siegesbeckiae 4.5-30g, Caulis Piperis Kadsurae 4.5-15g, Pheretima 4.5-15g, Semen Raphani 4.5-30g, Herba Plantaginis 4.5-25g, Folium Ginkgo 4.5-20g, ground beetle 1.5-9g, Radix Notoginseng 1.5-6g, Flos Chrysanthemi 4-10g.