CN107663384B - 一种荧光染料及其制备方法和用途 - Google Patents
一种荧光染料及其制备方法和用途 Download PDFInfo
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- CN107663384B CN107663384B CN201610573970.XA CN201610573970A CN107663384B CN 107663384 B CN107663384 B CN 107663384B CN 201610573970 A CN201610573970 A CN 201610573970A CN 107663384 B CN107663384 B CN 107663384B
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
- C09B23/04—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups one >CH- group, e.g. cyanines, isocyanines, pseudocyanines
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- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
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- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0008—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain
- C09B23/005—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being a COOH and/or a functional derivative thereof
- C09B23/0058—Methine or polymethine dyes, e.g. cyanine dyes substituted on the polymethine chain the substituent being a COOH and/or a functional derivative thereof the substituent being CN
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- C09B23/0091—Methine or polymethine dyes, e.g. cyanine dyes having only one heterocyclic ring at one end of the methine chain, e.g. hemicyamines, hemioxonol
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/532—Production of labelled immunochemicals
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- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
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Abstract
Description
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Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610573970.XA CN107663384B (zh) | 2016-07-20 | 2016-07-20 | 一种荧光染料及其制备方法和用途 |
EP17830454.9A EP3489323A4 (en) | 2016-07-20 | 2017-07-18 | FLUORESCENT DYE AND PRODUCTION METHOD AND USE THEREOF |
US16/318,762 US11365203B2 (en) | 2016-07-20 | 2017-07-18 | Fluorescent dye and preparation method and use thereof |
PCT/CN2017/093270 WO2018014820A1 (zh) | 2016-07-20 | 2017-07-18 | 一种荧光染料及其制备方法和用途 |
JP2019502739A JP7186448B2 (ja) | 2016-07-20 | 2017-07-18 | 蛍光染料及びその製造方法と使用 |
Applications Claiming Priority (1)
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CN201610573970.XA CN107663384B (zh) | 2016-07-20 | 2016-07-20 | 一种荧光染料及其制备方法和用途 |
Publications (2)
Publication Number | Publication Date |
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CN107663384A CN107663384A (zh) | 2018-02-06 |
CN107663384B true CN107663384B (zh) | 2020-05-12 |
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CN201610573970.XA Active CN107663384B (zh) | 2016-07-20 | 2016-07-20 | 一种荧光染料及其制备方法和用途 |
Country Status (5)
Country | Link |
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US (1) | US11365203B2 (zh) |
EP (1) | EP3489323A4 (zh) |
JP (1) | JP7186448B2 (zh) |
CN (1) | CN107663384B (zh) |
WO (1) | WO2018014820A1 (zh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108300456B (zh) * | 2018-01-26 | 2020-08-18 | 华南理工大学 | 一类具有聚集诱导发光性质的荧光化合物在有机胺检测中的应用 |
CN110498799B (zh) * | 2018-05-18 | 2022-07-05 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
CN111593052A (zh) * | 2019-04-28 | 2020-08-28 | 华东理工大学 | 一种rna检测与定量的方法 |
CN111592472B (zh) * | 2019-04-28 | 2022-10-21 | 纳莹(上海)生物科技有限公司 | 一种荧光染料及其制备方法和用途 |
CN110437219A (zh) * | 2019-07-09 | 2019-11-12 | 济南大学 | 一种检测粘度和二氧化硫双功能的荧光探针 |
CN112538482A (zh) * | 2019-09-23 | 2021-03-23 | 华东理工大学 | 一种rna检测与定量的方法 |
CN110702653B (zh) * | 2019-10-16 | 2020-11-24 | 华中科技大学 | 一种聚集诱导荧光探针在指纹荧光成像中的应用 |
CN113501790A (zh) * | 2020-03-23 | 2021-10-15 | 纳莹(上海)生物科技有限公司 | 一种荧光染料及其制备方法和用途 |
CN112876496B (zh) * | 2021-03-16 | 2022-01-28 | 南京邮电大学 | 一种有机小分子光学诊疗探针及其制备方法与应用 |
CN115703771A (zh) * | 2021-08-06 | 2023-02-17 | 纳莹(上海)生物科技有限公司 | 一种荧光染料及其制备方法和用途 |
CN113754603B (zh) * | 2021-08-12 | 2022-04-19 | 浙江工业大学 | 一种异恶唑类化合物作为粘度荧光探针的应用 |
CN114605376A (zh) * | 2022-04-21 | 2022-06-10 | 济南大学 | 一种检测半胱氨酸和粘度的双功能荧光探针及其制备 |
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DE3622136A1 (de) * | 1986-07-02 | 1988-01-07 | Basf Ag | Thienothiophenfarbstoffe |
GB0219896D0 (en) | 2002-08-27 | 2002-10-02 | Bayer Ag | Dihydropyridine derivatives |
US8153446B2 (en) | 2008-05-23 | 2012-04-10 | Kent State University | Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems |
WO2009152165A2 (en) | 2008-06-09 | 2009-12-17 | Plextronics, Inc. | Sulfonated polythiophenes comprising fused ring repeat units |
ES2307462B1 (es) * | 2008-06-30 | 2009-10-14 | Fundacion Universitaria San Pablo Ceu (70%) | Derivados de naftofurano y naftotiofeno como agentes antiproliferativos del cancer de pancreas y colon. |
WO2010074326A1 (en) * | 2008-12-25 | 2010-07-01 | Canon Kabushiki Kaisha | Probe for a biological specimen and labelling method and screening method using the probe |
CN102803924A (zh) * | 2009-06-05 | 2012-11-28 | 丹尼斯科美国公司 | 高流通量分子转子黏度测定法测定 |
CN104610774B (zh) | 2009-08-24 | 2017-07-18 | 独立行政法人情报通信研究机构 | 二阶非线性光学化合物及含有它的非线性光学元件 |
KR101985184B1 (ko) * | 2011-01-28 | 2019-06-03 | 주식회사 동진쎄미켐 | 신규한 유기염료 및 이의 제조방법 |
CN102146215B (zh) * | 2011-01-31 | 2014-04-02 | 大连理工大学 | 一类五甲川菁荧光染料、制备方法及其应用 |
WO2012103678A1 (zh) * | 2011-01-31 | 2012-08-09 | 大连理工大学 | 一类五甲川菁荧光染料、制备方法及其应用 |
JP2013194039A (ja) | 2012-03-22 | 2013-09-30 | Nippon Shokubai Co Ltd | ホウ素含有化合物及びその製造方法 |
US20130247992A1 (en) | 2012-03-22 | 2013-09-26 | Polyera Corporation | Polymeric Blends and Related Optoelectronic Devices |
CN102757659B (zh) * | 2012-07-24 | 2014-05-21 | 大连理工大学 | 一类咔唑类半菁荧光染料及其应用 |
SG11201502289RA (en) * | 2012-09-26 | 2015-04-29 | Agency Science Tech & Res | Fluorescent molecular rotors |
EP2940781A4 (en) * | 2012-12-28 | 2016-08-17 | Adeka Corp | LOADED BODY AND PHOTOELECTRIC CONVERSION ELEMENT |
KR101718867B1 (ko) * | 2014-06-02 | 2017-03-22 | 한국과학기술연구원 | 생체적합성 형광 나노입자 및 이의 용도 |
CN105062465B (zh) * | 2015-07-31 | 2018-06-15 | 山东大学 | 一类环境敏感型的α1-肾上腺素能受体近红外荧光配体及其应用 |
CN105566942A (zh) * | 2015-10-13 | 2016-05-11 | 华东理工大学 | 一种长发射波长荧光染料的制备方法 |
CN113277985B (zh) * | 2016-07-20 | 2023-07-28 | 纳莹(上海)生物科技有限公司 | 一种荧光探针及其制备方法和用途 |
-
2016
- 2016-07-20 CN CN201610573970.XA patent/CN107663384B/zh active Active
-
2017
- 2017-07-18 JP JP2019502739A patent/JP7186448B2/ja active Active
- 2017-07-18 US US16/318,762 patent/US11365203B2/en active Active
- 2017-07-18 EP EP17830454.9A patent/EP3489323A4/en active Pending
- 2017-07-18 WO PCT/CN2017/093270 patent/WO2018014820A1/zh unknown
Also Published As
Publication number | Publication date |
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JP7186448B2 (ja) | 2022-12-09 |
CN107663384A (zh) | 2018-02-06 |
US20190241584A1 (en) | 2019-08-08 |
US11365203B2 (en) | 2022-06-21 |
EP3489323A1 (en) | 2019-05-29 |
JP2019527279A (ja) | 2019-09-26 |
WO2018014820A1 (zh) | 2018-01-25 |
EP3489323A4 (en) | 2020-05-06 |
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