CN107638457A - A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition and preparation method thereof of disease in vain - Google Patents

A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition and preparation method thereof of disease in vain Download PDF

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Publication number
CN107638457A
CN107638457A CN201610595067.3A CN201610595067A CN107638457A CN 107638457 A CN107638457 A CN 107638457A CN 201610595067 A CN201610595067 A CN 201610595067A CN 107638457 A CN107638457 A CN 107638457A
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China
Prior art keywords
parts
chinese medicine
perch
eyeball
disease
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Pending
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CN201610595067.3A
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Chinese (zh)
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曲荟芬
李琳
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SRICK (TIANJIN) BIO-TECHNOLOGY Co Ltd
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SRICK (TIANJIN) BIO-TECHNOLOGY Co Ltd
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Publication of CN107638457A publication Critical patent/CN107638457A/en
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Abstract

The present invention relates to a kind of perch eyeball for the treatment of to light up the Chinese medicine composition and preparation method thereof of disease in vain, is prepared by rheum officinale, golden cypress, radix scutellariae, chrysanthemum, rde bean, the capsule of weeping forsythia and Radix Angelicae Sinensis.Its preparation process is:(1) Chinese medicine is crushed to 30 100 mesh, weighed by formula ratio, three-dimensional hybrid obtains traditional Chinese medicine powder;(2) mixed traditional Chinese medicine powder is put into extractor, adds 5 15 times of amount ethanol waters to soak 2 10 hours, be filtered to remove the dregs of a decoction, collect leaching liquor.Wherein, the weight of ethanol and water ratio is 1:1;(3) it is 1 to add the ethanol of 5 10 times of amounts and water weight ratio into the dregs of a decoction again:1 alcohol water blend, soak 2 10 hours, filter cleaner, collect leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,30 80 DEG C are concentrated under reduced pressure into original volume 10 50%;(5) filter cleaner is filling, every bottle of 0.5 2L, obtains finished product.Chinese medicine composition provided by the present invention have heat-clearing and damp-drying drug, purging intense heat and detonicating, cool blood detumescence, it is promoting blood circulation and removing blood stasis the effect of, treatment perch eyeball disease of lighting up in vain is evident in efficacy.

Description

A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition and preparation method thereof of disease in vain
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially it is a kind of treat perch eyeball light up in vain disease Chinese medicine composition and its Preparation method.
Background technology
Perch eyeball disease of lighting up in vain is a kind of common cultivation perch disease, is mainly in the spring and summer fingerling stage.Early stage perch There is white point in flake ball, gradually expands and covers whole eyeball, perch eyeball swelling, severe patient's exophthalmos come off, to raiser Revenue impact it is quite big.On perch eyeball light up in vain disease pathogenic factor it is still not fully aware of, it is due to bait to generally believe this disease Caused by expecting that stale or breeding water body pollutes.Mould is decomposed in the water body that perch eyeball lights up disease in vain is had suffered from, suspection is pathogenic One of bacterium.
Treatment perch eyeball there is no to light up in vain the specific drug of disease at present, mainly to carry out based on sterilization prevention work, perch one Denier suffers from this disease and takes renewal breeding water body more, feeds the measures such as fresh bait.China's natural resources of Chinese medicinal materials enriches, and Long-term clinical uses product Substantial amounts of experience is tired out, therefore it is the effective way for capturing this disease that exploitation, which can effectively treat the light up in vain Chinese medicine preparation of disease of perch, One of.
The content of the invention
The problem to be solved in the present invention is:A kind of overcome the deficiencies in the prior art, there is provided natural Chinese traditional medicines curative for effect Composition.
Another technical problem to be solved by the present invention is that:A kind of perch eyeball for the treatment of is provided to light up in vain the Chinese medicine preparation of disease.
Another technical problem to be solved by the present invention is that:The preparation method of above-mentioned Chinese medicine composition aqua is provided.
In order to solve the above technical problems, the technical solution adopted by the present invention is:A kind of perch eyeball for the treatment of is lit up in disease in vain Drug composition, it is characterised in that:It is prepared by the raw material of following mass fraction:Rheum officinale 12-22 parts, golden cypress 12-22 parts, radix scutellariae 10-20 parts, chrysanthemum 8-12 parts, rde bean 13-18 parts, capsule of weeping forsythia 10-20 parts, Radix Angelicae Sinensis 10-14 parts.
Further, the mass fraction of the optimum feed stock of the Chinese medicine composition is as follows:18 parts of rheum officinale, 16 parts of golden cypress, radix scutellariae 12 parts, 10 parts of chrysanthemum, 14 parts of rde bean, 16 parts of the capsule of weeping forsythia, 14 parts of Radix Angelicae Sinensis.
Further, the Chinese medicine composition is the conventional Chinese medicinal composition preparation for containing or not contain pharmaceutic adjuvant.
Further, the preparation method of the Chinese medicine composition aqua is:(1) Chinese medicine is crushed to 30-100 mesh, by formula Amount weighs, and three-dimensional hybrid obtains traditional Chinese medicine powder;(2) mixed traditional Chinese medicine powder is put into extractor, adding 5-15 times, to measure ethanol water-soluble Liquid soaks 2-10 hours, is filtered to remove the dregs of a decoction, collects leaching liquor.Wherein, the weight of ethanol and water ratio is 1:1;(3) again to medicine It is 1 that the 5-10 times of ethanol measured is added in slag with water weight ratio:1 alcohol water blend, soak 2-10 hours, filter cleaner, collect Leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,30-80 DEG C is concentrated under reduced pressure into original volume 10-50%;(5) filter cleaner fills Dress, every bottle of 0.5-2L, obtains finished product.
The present invention has the advantages and positive effects of:
(1) this prescription is according to tcm theory, scientific compatibility, from heat-clearing and damp-drying drug, purging intense heat and detonicating, promoting blood circulation and removing blood stasis, sharp The natural Chinese medicinal herb for the effect of water is subsided a swelling, a kind of Chinese medicinal aqua is made using Standardization Process.Through clinical examination, the Chinese medicinal aqua Treatment perch eyeball disease of lighting up in vain is evident in efficacy.
(2) Chinese medicinal aqua obtained by this prescription is pure natural, pollution-free, avoids the secondary pollution of perch culture pond, is A kind of really green veterinary drug.
(3) pharmacology of each Chinese medicine material of the present invention is:
Rheum officinale:Purging intense heat and detonicating, cool blood detumescence;
Golden cypress:Heat-clearing and damp-drying drug, purging intense heat and detonicating;
Radix scutellariae:Heat-clearing and damp-drying drug, purging intense heat and detonicating;
Chrysanthemum:Clear liver and improve vision, it is clearing heat and detoxicating;
Rde bean:Li Shui, subside a swelling, suppurate;
The capsule of weeping forsythia:It is clearing heat and detoxicating, dispersing swelling and dissipating binds;
Radix Angelicae Sinensis:It is promoting blood circulation and removing blood stasis.
The traditional Chinese medical science thinks, perch eyeball disease of lighting up in vain is that qi and blood is obstructed due to damp-heat accumulation in perch body, and institute is invaded in heat toxin Cause.Among formula, the sedimentation of rheum officinale bitter cold, energy clearing heat-fire, removing pattogenic heat from the blood and toxic material from the body, clearing heat and detoxicating, the external application energy purging intense heat and detonicating of energy is taken orally, it is cool Blood is subsided a swelling.Golden cypress bitter cold settles, and is longer than heat-clearing and damp-drying drug, and energy purging intense heat and detonicating, oral administration and externally are effective.Radix scutellariae taste bitter and cold, work( Energy heat-clearing and damp-drying drug, it is good at clear middle dampness-heat in upper jiao especially, has the effect of clearing heat-fire removing toxic substances concurrently.Radix scutellariae can use with golden cypress, rheum officinale and control fire The flourishing carbuncle sore tumefacting virus of poison.The pungent scattered hardship of chrysanthemum is let out, and be slightly cold heat-clearing, enters Liver Channel, can evacuate wind-heat of liver channel, and can let out clearly liver heat with Improving eyesight, caused red eye, swell pain can be attacked on wind-heat of liver channel, or irascibility with controlling, and because of its bitter cold nature, energy is clearing heat and detoxicating, therefore goes back Can be with controlling sore and toxic.Rde bean flat property and sweet taste, there is inducing diuresis for removing edema, the effect of dissipating the stasis of blood of suppurating.Capsule of weeping forsythia bitter cold, master enter the heart channel of Hang-Shaoyin, Can clearing away the heart-fire, solve sore, and can dissipation carbuncle swells knot gathers.The pungent row temperature of Radix Angelicae Sinensis is logical, is the key medicine of blood circulation promoting competent silt, with removing toxicity for eliminating carbuncles medicine Thing energy activating blood circulation and reducing swelling analgesic, can control sore from the beginning of swelling pain with using.
Above-mentioned seven flavor medicine compatible use, have heat-clearing and damp-drying drug, purging intense heat and detonicating, cool blood detumescence, it is promoting blood circulation and removing blood stasis the effect of, can pin Property treatment perch eyeball is lit up disease in vain.
Embodiment
The present invention is further described below by specific embodiment, following examples are descriptive, are not limits Qualitatively, it is impossible to which protection scope of the present invention is limited with this.
Embodiment 1
A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition of disease in vain, and the parts by weight of each raw material are as follows:18 parts of rheum officinale, golden cypress 16 parts, 12 parts of radix scutellariae, 10 parts of chrysanthemum, 14 parts of rde bean, 16 parts of the capsule of weeping forsythia, 14 parts of Radix Angelicae Sinensis be prepared.Its preparation method is:(1) Chinese medicine is crushed to 80 mesh, weighed by formula ratio, three-dimensional hybrid obtains traditional Chinese medicine powder;(2) mixed traditional Chinese medicine powder is put into extraction In tank, add 10 times of amount ethanol waters to soak 8 hours, be filtered to remove the dregs of a decoction, collect leaching liquor.Wherein, the weight of ethanol and water Than for 1:1;(3) it is 1 to add the ethanol of 8 times of amounts and water weight ratio into the dregs of a decoction again:1 alcohol water blend, soak 6 hours, Filter cleaner, collect leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,60 DEG C are concentrated under reduced pressure into original volume 20%;(5) mistake It is filling to filter out slag, every bottle of 1L, obtains finished product.
Embodiment 2
A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition of disease in vain, and the parts by weight of each raw material are as follows:12 parts of rheum officinale, golden cypress 22 parts, 20 parts of radix scutellariae, 8 parts of chrysanthemum, 18 parts of rde bean, 10 parts of the capsule of weeping forsythia, 10 parts of Radix Angelicae Sinensis be prepared.Its preparation method is:(1) will Chinese medicine is crushed to 80 mesh, is weighed by formula ratio, and three-dimensional hybrid obtains traditional Chinese medicine powder;(2) mixed traditional Chinese medicine powder is put into extractor In, add 10 times of amount ethanol waters to soak 8 hours, be filtered to remove the dregs of a decoction, collect leaching liquor.Wherein, the weight of ethanol and water ratio For 1:1;(3) it is 1 to add the ethanol of 8 times of amounts and water weight ratio into the dregs of a decoction again:1 alcohol water blend, soak 6 hours, mistake Slag is filtered out, collects leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,60 DEG C are concentrated under reduced pressure into original volume 20%;(5) filter Remove the gred filling, every bottle of 1L, obtain finished product.
Embodiment 3
A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition of disease in vain, and the parts by weight of each raw material are as follows:22 parts of rheum officinale, golden cypress 12 parts, 10 parts of radix scutellariae, 12 parts of chrysanthemum, 13 parts of rde bean, 20 parts of the capsule of weeping forsythia, 11 parts of Radix Angelicae Sinensis be prepared.Its preparation method is:(1) Chinese medicine is crushed to 80 mesh, weighed by formula ratio, three-dimensional hybrid obtains traditional Chinese medicine powder;(2) mixed traditional Chinese medicine powder is put into extraction In tank, add 10 times of amount ethanol waters to soak 8 hours, be filtered to remove the dregs of a decoction, collect leaching liquor.Wherein, the weight of ethanol and water Than for 1:1;(3) it is 1 to add the ethanol of 8 times of amounts and water weight ratio into the dregs of a decoction again:1 alcohol water blend, soak 6 hours, Filter cleaner, collect leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,60 DEG C are concentrated under reduced pressure into original volume 20%;(5) mistake It is filling to filter out slag, every bottle of 1L, obtains finished product.
Clinical test
Experiment 1
The fishpond of Tianjin Baodi county one, about 20 mu of area, launches a collection of perch seed by the end of April, is fallen ill in time early summer, The visible fragmentary rotten eye perch of the water surface.Salvage and find that there is white dot at perch eyeball center, it is not of uniform size depending on the situation of being in a bad way, sternly The whole eyeball of severe one is covered by white dot, perch eyeball swelling, and some even protrusions come off.It is typical case through local Disease Diagnosis of Veterinary Perch eyeball is lit up disease in vain, and the bleaching powder of full pool spilling head 0.02 ‰ sterilizes immediately, but DeGrain, perch eyeball center white spot Area has no diminution, while with eyeball swelling.Then the Chinese medicinal aqua treatment obtained by the embodiment of the present invention 1 is used instead, according to 1L Chinese medicinal aqua:The ratio in 3 mu of ponds high concentration before liquid material platform before feeding, which is splashed, carries out dipping, 2 times a day, continuously splashes 6 days.Fry is salvaged in medication after 3 days can see that the swelling of perch eyeball is disappeared, and eyeball center white speck area is also obviously reduced.After After continuous medication 3 days, perch eyeball center white spot is wholly absent, and jumpbogroup recovery from illness, the state of an illness is effectively controlled.
Testing 1 result shows, using the Chinese medicinal aqua obtained by the embodiment of the present invention 1, to take the method for dipping to treat perch Eyeball is lit up in vain, and disease is rapid-action, curative effect is good, is adapted to clinical expansion to use.
It is described above, be only the preferred embodiments of the present invention, be it is illustrative rather than limited, can be according to being limited Scope includes several embodiments, therefore changing and modifications in the case where not departing from present general inventive concept, should belong to the present invention's Within protection domain.

Claims (5)

1. a kind of perch eyeball for the treatment of is lit up the Chinese medicine composition of disease in vain, it is characterised in that:Prepared by the raw material of following mass fraction Form:
Rheum officinale 12-22 parts, golden cypress 12-22 parts, radix scutellariae 10-20 parts, chrysanthemum 8-12 parts, rde bean 13-18 parts, capsule of weeping forsythia 10-20 parts, Radix Angelicae Sinensis 10-14 parts.
2. a kind of perch eyeball for the treatment of according to claim 1 is lit up the Chinese medicine composition of disease in vain, it is characterised in that:It is optimal former The mass fraction of material is as follows:
18 parts of rheum officinale, 16 parts of golden cypress, 12 parts of radix scutellariae, 10 parts of chrysanthemum, 14 parts of rde bean, 16 parts of the capsule of weeping forsythia, 14 parts of Radix Angelicae Sinensis.
3. a kind of perch eyeball for the treatment of according to claim 1 or 2 is lit up the Chinese medicine composition of disease in vain, it is characterised in that:Should Chinese medicine composition is the various conventional extract oral medicine dosage forms for containing or not contain pharmaceutic adjuvant.
4. a kind of perch eyeball for the treatment of according to claim 3 is lit up the Chinese medicine composition of disease in vain, it is characterised in that:The system Agent can be aqua.
5. it is a kind of prepare treatment perch eyeball as claimed in claim 4 light up in vain disease Chinese medicinal aqua method, it is characterised in that Preparation method is:(1) Chinese medicine is crushed to 30-100 mesh, weighed by formula ratio, three-dimensional hybrid obtains traditional Chinese medicine powder;(2) after mixing Traditional Chinese medicine powder put into extractor, add 5-15 times to measure ethanol water immersion 2-10 hours, be filtered to remove the dregs of a decoction, collect extraction Liquid.Wherein, the weight of ethanol and water ratio is 1:1;(3) it is 1 to add the 5-10 times of ethanol measured with water weight ratio into the dregs of a decoction again: 1 alcohol water blend, soak 2-10 hours, filter cleaner, collect leaching liquor;(4) the gained leaching liquor of combining step 2 and 3,30- 80 DEG C are concentrated under reduced pressure into original volume 10-50%;(5) filter cleaner is filling, every bottle of 0.5-2L, obtains finished product.
CN201610595067.3A 2016-07-21 2016-07-21 A kind of perch eyeball for the treatment of is lit up the Chinese medicine composition and preparation method thereof of disease in vain Pending CN107638457A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1644077A (en) * 2005-01-11 2005-07-27 冯绍宽 Plant additive premixed forage for aquatic culture and bait therefrom
CN105617219A (en) * 2014-10-25 2016-06-01 孙婷婷 Compound Chinese herb preparation for preventing and treating fresh water fish bacterial diseases, and production method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1644077A (en) * 2005-01-11 2005-07-27 冯绍宽 Plant additive premixed forage for aquatic culture and bait therefrom
CN105617219A (en) * 2014-10-25 2016-06-01 孙婷婷 Compound Chinese herb preparation for preventing and treating fresh water fish bacterial diseases, and production method thereof

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