CN107519036A - A kind of striae of pregnancy spray containing polypeptide and preparation method thereof - Google Patents
A kind of striae of pregnancy spray containing polypeptide and preparation method thereof Download PDFInfo
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- CN107519036A CN107519036A CN201710797790.4A CN201710797790A CN107519036A CN 107519036 A CN107519036 A CN 107519036A CN 201710797790 A CN201710797790 A CN 201710797790A CN 107519036 A CN107519036 A CN 107519036A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention discloses a kind of striae of pregnancy spray containing polypeptide, it contains following components in parts by weight：0.1 1 parts of polypeptide powders, 1 10 parts of antioxidants, 18 parts of accelerator, 15 parts of NMFs, 0.1 0.8 parts of buffers, 0.01 0.09 portions of preservatives, 20 50 parts of sodium hyaluronates, 0.1 0.4 parts of active growth factors and 60 100 parts of pure water.The invention also discloses a kind of preparation method of the striae of pregnancy spray containing polypeptide.Striae of pregnancy spray of the kind containing polypeptide of the present invention is applied to the region of striae of pregnancy in the form of spraying, it is not necessary to is coated again with palm, avoids the infection of bacterium, spray absorbability is good in addition, can strengthen the stretch capability of skin and nourish skin.
Description
Technical field
The present invention relates to a kind of striae of pregnancy spray, more particularly to a kind of striae of pregnancy spray containing polypeptide and preparation method thereof.
Background technology
Due to the gestational period hormonal influence, abdominal distention makes elastic fibers and the collagenous fibres damage or disconnected of skin in addition
Splitting, skin of abdomen is thinning to attenuate, and pink or aubergine the wavy decorative pattern that some width are different, different in size occurs, point
Puerperium, these decorative patterns can fade away, and leave white or argenteous glossiness scar strain line, i.e. striae of pregnancy.Striae of pregnancy master
Appear on stomach wall, it is also possible to appear in outside, buttocks, chest, rear waist and arm etc. in thigh, primipara is the brightest
It is aobvious, once striae of pregnancy occur would not disappear, and with cutis laxa, breast tenesmus, abdominal fat accumulation, have a strong impact on woman
The figure in female's postpartum and physical and mental health, at present, also occur on the market it is a variety of reparation striaes of pregnancy modes, such as essential oil therapy,
Skin method, electrophototherapy and repairing paste is changed to smear.
But there is following defect in the existing mode for repairing striae of pregnancy：
(1) essential oil therapy treatment cycle is long, takes effect slowly, changes skin method and striae of pregnancy is peeled using chemistry, skin is caused
Irreversible damage, electrophototherapy need repeatedly to treat in batches, can stay scar, and, it is necessary to be coated with palm after repairing paste smearing
Uniformly, this will bring bacterium on hand into skin, cause superinfection；
(2) existing repairing paste main purpose is to keep the elastic and soft of skin, but absorbs poor, function list
One.
The content of the invention
For overcome the deficiencies in the prior art, an object of the present invention is to provide a kind of striae of pregnancy spray containing polypeptide
Agent, the spray are applied to the region of striae of pregnancy in the form of spraying, it is not necessary to are coated again with palm, avoid the sense of bacterium
Dye, spray absorbability is good in addition, can strengthen the stretch capability of skin and nourish skin.
Second object of the present invention is to provide for a kind of preparation method of the striae of pregnancy spray containing polypeptide, the preparation side
Method step is simple, substantial amounts of manpower and materials can be saved, suitable for industrialized production.
An object of the present invention adopts the following technical scheme that realization：
A kind of striae of pregnancy spray containing polypeptide, it contains following components in parts by weight：
Further, the striae of pregnancy spray containing polypeptide contains following components in parts by weight：
Further, the polypeptide powder includes leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, the leech Gly-His-Lys, ox
Newborn Gly-His-Lys, the weight ratio of collagen Gly-His-Lys are (2-8)：(4-8)：1.
Further, the leech Gly-His-Lys, cow's milk Gly-His-Lys, the weight ratio of collagen Gly-His-Lys are (4-6)：(5-6)：1.
Further, the antioxidant is vitamin C, VCE, vitamin C sugar ester, vitamin E acetic acid
It is more than one or both of ester and tocopherol.
Further, the accelerator is more than one or both of lecithin, sodium taurocholate, oleic acid and polysorbate.
Further, the NMF be one or both of glycerine, propane diols, sorbierite and Sodium Hyaluronate with
On.
Further, the buffer is more than one or both of glycine, boric acid, sodium acid carbonate.
Further, the preservative is more than one or both of ethanol, anesin, benzoic acid, sorbic acid.
Realize that second object of the present invention can reach by adopting the following technical scheme that：
A kind of preparation method of the striae of pregnancy spray containing polypeptide, including：
Batching step：Under normal temperature, sodium hyaluronate, active growth factor are dissolved in pure water by proportioning, stirs, stirs
Rotating speed be 500r/min-800r/min, time 6-10min, obtain the first prefabricated solution；
Blend step：Polypeptide powder is dissolved in the first prefabricated solution, is warming up to 35-45 DEG C, antioxidant is added, promotes
Agent, NMF, buffer and preservative, it is well mixed, the rotating speed of mixing is 1000r/min-1200r/min, time 10-
15min, obtain the second prefabricated solution；
Sterilization steps：After the second prefabricated solution is cooled to normal temperature, sterilize, packaging, obtain the striae of pregnancy spray containing polypeptide.
The beneficial effects of the present invention are：
1st, the spray containing polypeptide of the invention is applied to the region of striae of pregnancy in the form of spraying, it is not necessary to palm again
Coating, avoids the infection of bacterium, and spray absorbability is good in addition, can strengthen the stretch capability of skin and nourish skin；
2nd, the preparation method of the striae of pregnancy spray of the invention containing polypeptide, the preparation method step is simple, can save a large amount of
Manpower and materials, suitable for industrialized production.
Embodiment
Below, with reference to embodiment, the present invention is described further, it is necessary to which explanation is, what is do not collided
Under the premise of, new embodiment can be formed between various embodiments described below or between each technical characteristic in any combination.
A kind of striae of pregnancy spray containing polypeptide, it contains following components in parts by weight：
As mode is further carried out, the striae of pregnancy spray containing polypeptide contains following components in parts by weight：
As the mode that further carries out, polypeptide powder includes leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, HIRULOG
Powder, cow's milk Gly-His-Lys, the weight ratio of collagen Gly-His-Lys are (2-8)：(4-8)：1.
As the mode that further carries out, leech Gly-His-Lys, cow's milk Gly-His-Lys, the weight ratio of collagen Gly-His-Lys are (4-6)：
(5-6)：1.
Leech polypeptide is the peptides thrombin inhibitor gone out using hirudin as stencil design, its amino acid number with it is suitable
Sequence is also different and different because of designer；Domestic and foreign scholars are tested by animal model and volunteer, to hirudin, leech albumen
The characteristic of polypeptide has carried out substantial amounts of research.Russian scientist is (coronary heart disease, rheumatism, slow by the way that 57 are suffered from various disease
Property tuberculosis) patient tested, confirm hirudin be effective to anti-Trostin M, Markwardt etc. research also show
Hirudin is to good anti thrombotic action.Leech polypeptide also show good anti-freezing and anti-bolt in zoopery
Effect.With stimulate the menstrual flow, broken stasis of blood detumescence the effect of, be mainly used in abdominal mass stomachache, store blood, traumatic injury, extravasated blood are had a pain and carbuncle swells are red
The treatment of the diseases such as poison, restructuring leech class polypeptide drugs are produced using genetic engineering, to substitute Acid polypeptide or be used as anti-freezing stagnation resolvation
The adding ingredient of medicine, it can realize completely.
The preparation method of leech polypeptide powder can refer to disclosed in the patent of invention of Application No. 201510908591.7
A kind of method that polypeptide is produced from golden-rimmed leech.
Cow's milk Gly-His-Lys derive from cow's milk, can be directly by intestinal absorption, and blood is absorbed on the premise of being not required to through digestion
Liquid, quick production capacity.The class morphine active component contained in cow's milk Gly-His-Lys can accelerate cell movement, improve the functions such as immunocompetence.
The preparation method of cow's milk Gly-His-Lys can refer to a kind of high disclosed in the patent of invention of Application No. 201510905853.4
The method that frequency electromagnetic waves auxiliary prepares milk protein polypeptide.
Collagen polypeptide is to repair collagen type, and albumen can be reduced with advancing age and slowly, it can be seen that,
Collagen plays very important role in the health and beauty of human body skin really, and collagen polypeptide can more have
Effect ground penetrates into cuticula, skin corium, plays and extends the Skin Cell life-span, suppresses Cell membrane lipids peroxidating, resistance oxidation freely
Attack of the base to DNA, the activity for suppressing tyrosine, cutaneous immunisation ability is improved, skin water holding water holding capacity is improved, promotes collagen
Synthesis and dermal cell hyaluronic acid the multiple efficacies such as synthesis.It is more through collagen due to the characteristic of collagen polypeptide
Skin after peptide treatment can be improved and be nourished for a long time, and can maintain optimum curative effect 5-10, collagen polypeptide, can be with
By human body active and accessible absorption, without digestion, made full use of for bodily tissue.And marine collagen polypeptide average mark
Son amount is smaller, or even only 2-4 Amino acid profile, far smaller than ordinary peptide.
Collagen polypeptide effect：
1st, moisturizing：Collagen polypeptide contains hydrophilic NMF, into rear directly formation collagen in vivo, and
The skin moment is allowed to keep the tender state of moistening, water；
2nd, nutrition：Collagen polypeptide is strong to the permeability of skin, can pass through cuticula and is combined with skin epithelial cell, is joined
Metabolism with improvement Skin Cell, strengthens the Collage Activitv in skin；It can keep cuticula moisture and fibre structure
Integrality, improve Skin Cell living environment and promote the metabolism of skin histology, strengthen blood circulation, reach and hereby moisten skin
Purpose；
3rd, skin lightening：The gloss of skin depends on water content, and the good water holding capacity of collagen makes skin water profit glossy, dissipated
Send out the brilliance of health；
4th, Firm：After collagen polypeptide is absorbed by the skin, it is filled between dermis of skin, increases skin tight ness rating,
Skin tension is produced, pore is reduced, makes skin tight and high resilience；
5th, it is wrinkle resistant：Plentiful collagen layer, Skin Cell is propped up in corium, with reference to moisturizing and the work of suppression wrinkle
With, reach jointly unfold coarse groove, desalination microgroove the effect of；
6th, repair：Collagen polypeptide can directly penetrate into skin bottom, and good with the new of surrounding tissue and property, can assist thin
Born of the same parents manufacture collagen, promote skin cell normal growth.Itself also there is anti-inflammatory and renewal skin simultaneously.
The preparation method of collagen polypeptide powder can refer to disclosed in the patent of invention of Application No. 201210087343.7
A kind of application with fowl leather for the method for micromolecular collagen polypeptide powder and its in juice drinks.
As the mode that further carries out, antioxidant is vitamin C, VCE, vitamin C sugar ester, dimension life
It is more than one or both of plain E acetates and tocopherol.Antioxidant can prevent the dysgenic material of oxygen, and it is one
Class can help to capture and neutralize free radical, so as to dispel a kind of material that free radical damages to human body, it can in addition contain extend spray
The resting period of agent.
As the mode that further carries out, accelerator is one kind or two in lecithin, sodium taurocholate, oleic acid and polysorbate
More than kind.Accelerator can promote Transdermal absorption.
As the mode that further carries out, NMF be one kind in glycerine, propane diols, sorbierite and Sodium Hyaluronate or
It is two or more.NMF can keep the water imbibition and moisture retention of skin.
As the mode that further carries out, buffer is more than one or both of glycine, boric acid, sodium acid carbonate.
Buffer can maintain pH value stable in spray.
As the mode that further carries out, preservative be ethanol, anesin, benzoic acid, one kind in sorbic acid or
It is two or more.Preservative can extend the standing time of spray with mould proof fungi-proofing.
Sodium hyaluronate is a kind of acid mucopolysaccharide, and into after human body, by the glucose in human body, actively crawl activates, and stimulates certainly
Body sodium hyaluronate regenerates, and active sodium hyaluronate cytoplasm acts on whole body, reach the lasting moisturizing of human body cell deep layer, can be with by spraying
Increase internal sodium hyaluronate total content, improve the deficiency of sodium hyaluronate in human body, sodium hyaluronate reparative factor and collagenous fibres reparative factor
By digesting, being absorbed into blood, each cell of through body.
Active growth factor is the cell factor for having stimulating cellular growth activity, is had the effect that：1st, thoroughly：Directly
Nucleus is reached, revision points, promotes cell division breeding, metabolism.Disease is fundamentally treated, lifts physical function,
Extend the life-span, beautify appearance；2nd, it is quick：It is the acme achievement of genetic engineering and nanometer technology, less than 200 times of cell, 80
Second reach cell interior；3rd, comprehensively：Eight big system of direct regulation and control human body, active cell reach optimal metaboilic level；4th, safety：
Research shows, the growth factor secreted by the C.G.F. and human body itself that are extracted in high-quality chlorella is just the same, to human body without
Toxic side effect and dependence.
The preparation method of the above-mentioned striae of pregnancy spray containing polypeptide, including：
Batching step：Under normal temperature, sodium hyaluronate, active growth factor are dissolved in pure water by proportioning, stirs, stirs
Rotating speed be 500r/min-800r/min, time 6-10min, obtain the first prefabricated solution；
Blend step：Polypeptide powder is dissolved in the first prefabricated solution, is warming up to 35-45 DEG C, antioxidant is added, promotes
Agent, NMF, buffer and preservative, it is well mixed, the rotating speed of mixing is 1000r/min-1200r/min, time 10-
15min, obtain the second prefabricated solution；
Sterilization steps：After the second prefabricated solution is cooled to normal temperature, sterilize, packaging, obtain the striae of pregnancy spray containing polypeptide.
It is specific embodiment of the present invention below, used raw material, equipment etc. remove special limit in the following embodiments
It can be obtained outside fixed by buying pattern.
Embodiment 1-5
Embodiment 1-5 content is as shown in the table：
The embodiment 1-5 of table 1 content
| Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Embodiment 5 | |
| Polypeptide powder | 0.5 | 0.6 | 0.7 | 0.2 | 1 |
| Antioxidant | 2 | 3 | 4 | 1 | 7 |
| Accelerator | 3 | 5 | 6 | 1 | 7 |
| NMF | 2 | 3 | 4 | 1 | 5 |
| Buffer | 0.2 | 0.4 | 0.5 | 0.1 | 0.7 |
| Preservative | 0.02 | 0.03 | 0.05 | 0.01 | 0.09 |
| Sodium hyaluronate | 31 | 36 | 40 | 22 | 49 |
| Active growth factor | 0.2 | 0.24 | 0.3 | 0.1 | 0.4 |
| Pure water | 70 | 80 | 90 | 64 | 100 |
Wherein, the polypeptide powder of embodiment 1 is leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, and the weight ratio of three is 4：
5：1, the polypeptide powder of embodiment 2 is leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, and the weight ratio of three is 5：5：1, implement
The polypeptide powder of example 3 is leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, and the weight ratio of three is 6：6：1, the polypeptide of embodiment 4
Powder is leech Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, and the weight ratio of three is 2：4：1, the polypeptide powder of embodiment 5 is leech
Gly-His-Lys, cow's milk Gly-His-Lys, collagen Gly-His-Lys, the weight ratio of three is 8：8：1；
The antioxidant of embodiment 1 is vitamin C, and the antioxidant of embodiment 2 is VCE, embodiment 3
Antioxidant is vitamin C sugar ester, Vitwas E using weight ratio as 2:1 mixture, the antioxidant of embodiment 4 are
Tocopherol, the antioxidant of embodiment 5 is vitamin C；
The accelerator of embodiment 1 is vitamin C, and the accelerator of embodiment 2 is lecithin, and the accelerator of embodiment 3 is ovum
Phosphatide and using weight ratio as 1:1 mixture, the accelerator of embodiment 4 is polysorbate, and the accelerator of embodiment 5 is oleic acid；
The NMF of embodiment 1 is vitamin C, and the NMF of embodiment 2 is lecithin, and the NMF of embodiment 3 is ovum
Phosphatide and using weight ratio as 1:1 mixture, the NMF of embodiment 4 is polysorbate, and the NMF of embodiment 5 is oleic acid；
The buffer of embodiment 1 is glycine, and the buffer of embodiment 2 is sodium acid carbonate, and the buffer of embodiment 3 is boron
Acid, the buffer of embodiment 4 is boric acid, and the buffer of embodiment 5 is sodium acid carbonate；
The preservative of embodiment 1 is anesin, and the preservative of embodiment 2 is benzoic acid, and the preservative of embodiment 3 is
Benzoic acid, the preservative of embodiment 4 is benzoic acid, and the preservative of embodiment 5 is anesin.
The embodiment 1-5 striae of pregnancy spray containing polypeptide is made by following preparation method, and preparation method includes：
Batching step：Under normal temperature, sodium hyaluronate, active growth factor are dissolved in pure water by proportioning, stirs, stirs
Rotating speed be 500r/min-800r/min, time 6-10min, obtain the first prefabricated solution；
Blend step：Polypeptide powder is dissolved in the first prefabricated solution, is warming up to 35-45 DEG C, antioxidant is added, promotes
Agent, NMF, buffer and preservative, it is well mixed, the rotating speed of mixing is 1000r/min-1200r/min, time 10-
15min, obtain the second prefabricated solution；
Sterilization steps：After the second prefabricated solution is cooled to normal temperature, sterilize, packaging, obtain the striae of pregnancy spray containing polypeptide.
Comparative example 1
The difference from Example 2 of comparative example 1 is that the polypeptide powder of comparative example 1 is leech Gly-His-Lys.
Comparative example 2
The difference from Example 2 of comparative example 2 is, the polypeptide powder of comparative example 2 is leech Gly-His-Lys, cow's milk Gly-His-Lys, both
Weight ratio be 1：1.
Comparative example 3
The difference from Example 2 of comparative example 3 is, the polypeptide powder of comparative example 3 is leech Gly-His-Lys, collagen Gly-His-Lys,
The weight ratio of three is 5：1.
Effect assessment and performance detection
Efficacy validation is tested
Experiment reagent：Embodiment 1-5 and comparative example 1-3 spray
Subject Population：The people of volunteer 100 after fertility, wherein 66 people is gave birth to a tire, 30 people are to give birth to two tires, 4 people
To give birth to triplet, volunteer is in 1-2 apart from the production time, and every volunteer has serious striae of pregnancy with it.
Test method：Volunteer begins to use spray for first day from experiment, and usage time is 6 months, sooner or later each daily equal
Even spraying is once.
Result of the test：Obtained result is as shown in the table.
The embodiment 1-5 of table 2 and comparative example 1-3 result of the tests
a:Striae of pregnancy bar number≤5
b:Striae of pregnancy bar number ＞ 5
From table 2, the striae of pregnancy spray containing polypeptide of this programme can effectively repair striae of pregnancy, and HIRULOG
Powder, cow's milk Gly-His-Lys, the effect being used cooperatively of collagen Gly-His-Lys are applied in combination all more than their exclusive uses or both
It is excellent, there is obvious synergistic function, wherein, embodiment 2 is optimum embodiment.
Above-mentioned embodiment is only the preferred embodiment of the present invention, it is impossible to the scope of protection of the invention is limited with this,
The change and replacement for any unsubstantiality that those skilled in the art is done on the basis of the present invention belong to institute of the present invention
Claimed scope.
Claims (10)
1. a kind of striae of pregnancy spray containing polypeptide, it is characterised in that it contains following components in parts by weight：
2. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that its contain in parts by weight with the following group
Point：
3. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the polypeptide powder include leech Gly-His-Lys,
Cow's milk Gly-His-Lys, collagen Gly-His-Lys, the leech Gly-His-Lys, cow's milk Gly-His-Lys, the weight ratio of collagen Gly-His-Lys are (2-8)：(4-
8)：1.
4. the striae of pregnancy spray containing polypeptide as claimed in claim 3, it is characterised in that the leech Gly-His-Lys, cow's milk Gly-His-Lys, glue
The weight ratio of former protein peptide powder is (4-6)：(5-6)：1.
5. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the antioxidant is vitamin C, dimension
It is more than one or both of raw plain C ethylethers, vitamin C sugar ester, Vitwas E and tocopherol.
6. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the accelerator is lecithin, cholic acid
It is more than one or both of sodium, oleic acid and polysorbate.
7. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the NMF be glycerine, propane diols,
It is more than one or both of sorbierite and Sodium Hyaluronate.
8. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the buffer be glycine, boric acid,
It is more than one or both of sodium acid carbonate.
9. the striae of pregnancy spray containing polypeptide as claimed in claim 1, it is characterised in that the preservative is ethanol, trichlorine uncle
It is more than one or both of butanol, benzoic acid, sorbic acid.
A kind of 10. preparation method of striae of pregnancy spray containing polypeptide as described in claim any one of 1-9, it is characterised in that bag
Include：
Batching step：Under normal temperature, sodium hyaluronate, active growth factor are dissolved in pure water by proportioning, stirred, stirring turns
Speed is 500r/min-800r/min, time 6-10min, obtains the first prefabricated solution；
Blend step：Polypeptide powder is dissolved in the first prefabricated solution, is warming up to 35-45 DEG C, adds antioxidant, accelerator, guarantor
Humectant, buffer and preservative, it is well mixed, the rotating speed of mixing is 1000r/min-1200r/min, time 10-15min,
Obtain the second prefabricated solution；
Sterilization steps：After the second prefabricated solution is cooled to normal temperature, sterilize, packaging, obtain the striae of pregnancy spray containing polypeptide.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109381357A (en) * | 2018-12-13 | 2019-02-26 | 广州宝莱生物科技有限公司 | A kind of anti-acne moisturizing leech freeze-dried powder |
| CN110151595A (en) * | 2019-06-25 | 2019-08-23 | 天津盛世永业科技发展有限公司 | The high efficiency composition system for preventing and treating striae of pregnancy and its application in cosmetics |
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| CN109381357B (en) * | 2018-12-13 | 2021-09-03 | 广州宝莱生物科技有限公司 | Leech freeze-dried powder capable of removing acne and moisturizing skin |
| CN110151595A (en) * | 2019-06-25 | 2019-08-23 | 天津盛世永业科技发展有限公司 | The high efficiency composition system for preventing and treating striae of pregnancy and its application in cosmetics |
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Application publication date: 20171229 |