CN106913485A - A kind of skin care item for preventing and treating striae of pregnancy and preparation method thereof - Google Patents
A kind of skin care item for preventing and treating striae of pregnancy and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The present invention provides a kind of skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：40~70 parts of 2~10 parts of collagen peptide, 1~5 part of catechin, 1~5 part of Gotu Kola P.E, 0.5~3 part of vitamin C, 0.1~2 part of EGF, 5~15 parts of vegetable oil, 1~5 part of cetearyl glucoside, 1~3 part of isopropyl myristate, 1~3 part of ethylhexyl palmitate, 1~5 part of glycerine, 1~4 part of cetostearyl alcohol, 1~3 part of propane diols, 0.1~1 part of preservative and water.The invention belongs to cosmetic technical field, the skin care item energy deep layer nourishes rough skin of the preventing and treating striae of pregnancy that the present invention is provided, cell growth can be promoted, rebuild the destroyed fibre structures such as belly, promote the synthesis and reparation of collagen and fibronectin, safety is gentle, improves crackle symptom, desalinate striae of pregnancy, realize the preventing and treating of striae of pregnancy.
Description
Technical field
The invention belongs to cosmetic technical field, more particularly to a kind of skin care item and its preparation side for preventing and treating striae of pregnancy
Method.
Background technology
Skin contains abundant elastic fibers and reticular fibre, it is generally the case that Elastic fibers remain with muscle
Certain tension force, can within the specific limits stretch or expand and avoid the damage of skin.Women later stage of pregnancy, by uterus gradually
The influence of increase, elastic fibers of skin starts gradually to extend with abdominal muscles, beyond the normal range (NR) that can be born, causes subcutaneous
The be rich in collagen fabric of tissue and elastin laminin are broken because being unable to undergo expansion, produce striae of pregnancy.The formation of striae of pregnancy
Position, based on belly, appearance is likely at other positions such as femoribus internus, breast, and center of the distribution often by body is outside
Enclose radiation, into parallel shape or radial, and color than skin, other positions are deeper.
Striae of pregnancy is once produced, it is difficult to is voluntarily disappeared, though health hazard will not be brought, has been had a strong impact on postpartum women's
Figure and physical and mental health.Striae of pregnancy common at present is dispelled or desalination method includes：(1) essential oil champignon method, the course for the treatment of of the method
It is more long, there are certain technical requirements to champignon operation, effect is also difficult to reach preferable degree, can be reached through 1 year effect of reparation
To 40% or so；(2) change skin method, carry out changing skin by the method for physics or chemistry, although the method instant effect, wound compared with
Greatly, sensitive skin quality be also easy to cause new scar, and easily cause adverse reaction using Chemopeel agent etc.；(3) laser is treated
Method, the method is not suitable for large area treatment, and the technical requirements to laser operations are high, relatively costly, and anaphase effect is inadequate
It is preferable；(4) creams massage, the method promotes absorption and the skin of active component by using cosmetics combination with massaging is repaired
Reparation, operate it is more convenient, have no side effect, easily received by consumer, but repair cosmetics quality it is uneven, part
Repairing cosmetics can only play conventional moisturizing and moisturizing effect, it is impossible to realize preferable repairing effect.
Chinese patent application CN 101152138 discloses a kind of cosmetic product with pregrant abdominal stretch marks-removing effect, comprising sweet
The compositions such as apricot kernel oil, olive oil, Gotu Kola P.E, small molecule broad bean polypeptide, the bionical peptide of EGF and vitamin grain,
The bionical peptide of EGF is wrapped up using nanometer technology, by Gotu Kola P.E and small molecule broad bean polypeptide, epidermis
The synergistic function of the various nutrients such as the bionical peptide of growth factor, penetrates into the elastic fibrous tissue of skin, promotes skin collagen
Synthesis, recover skin vigor and elasticity, can weaken the width of striae of pregnancy, length and color, but repairing effect is still not enough managed
Think.
Chinese patent application CN 101791283 discloses a kind of cosmetics for eliminating striae of pregnancy and scar, preparing raw material
Including niacinamide, epithelical cell growth factor, vitamin B2, Asiaticoside, cupu oil and collagen etc., clinical repair statistics
Display have preferable striae of pregnancy repairing effect, but epithelical cell growth factor, Asiaticoside, collagen and niacinamide use
Amount is larger, causes relatively costly and required frequency of use (3 times a day) higher.
With the improvement of living standards with the lifting of awareness of safety, creams massage is increasingly becoming the striae of pregnancy treatment of main flow
Method.Therefore it provides a kind of safety is gentle, prevention effect stabilization and lower-cost skin care item will cater to the need of consumers in general
Ask, with wide market prospects.
The content of the invention
To solve problems of the prior art, inventor provides a kind of skin care item for preventing and treating striae of pregnancy, passes through
The combination of collagen peptide, catechin, Gotu Kola P.E and EGF etc., energy deep layer nourishes rough skin, can promote
Enter cell growth, rebuild the destroyed fibre structures such as belly, promote the synthesis and reparation of collagen and fibronectin, safety
Gently, improve crackle symptom, desalinate striae of pregnancy, realize the preventing and treating of striae of pregnancy；By adding a small amount of vitamin C, work can be reduced
Property composition loss, improve skin care item stable effect.Based on above-mentioned discovery, so as to complete the present invention.
The purpose of the present invention will be further described in detail below reflect and description.
The present invention provides a kind of skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：Collagen egg
White 2~10 parts of peptide, 1~5 part of catechin, 1~5 part of Gotu Kola P.E, 0.5~3 part of vitamin C, EGF 0.1
~2 parts, 5~15 parts of vegetable oil, 1~5 part of cetearyl glucoside, 1~3 part of isopropyl myristate, palm acid ethyl oneself
40~70 parts of 1~3 part of ester, 1~5 part of glycerine, 1~4 part of cetostearyl alcohol, 1~3 part of propane diols, 0.1~1 part of preservative and water.
Collagen peptide is obtained by collagen or gelatin through enzymolysis, and molecular weight is normally no higher than 3000 dalton.It is of the invention
The molecular weight of collagen peptide is relatively low (being less than 1500 dalton), beneficial to absorption, can supply skin histology and structure nutritional ingredient,
Increase skin hydratability, improve Skin Cell environment, make the collagen increased activity in skin, promote the new of skin histology
Old metabolism.
Catechin (catechin) is topmost composition in millet paste, in bitter taste, is obtained by being extracted from tealeaves, tool
There are various functions such as prevention and cure of cardiovascular disease, obesity controlling, pre- anti-cancer, free radical can be removed, be commonly used for antioxidant,
Dyestuff and tanning industry also obtain wide application.In system of the present invention, catechin plays good whitening moisturizing effect,
Improve the compatibility with skin histology.
Gotu Kola P.E has oxidation resistant effect, can activate epithelial cell, promotes normal granulation tissue to be formed, and promotes
The reparation of elastomer is broken, has strengthened the ductility and toughness of skin, realized the quick renewal of skin histology.
EGF is naturally occurring in human body, can activate multi-signal albumen in Skin Cell, promotes skin group
The wound repair and normal growth knitted, improve the shared in skin ratio of neoblast, increase cytoplasm, promote skin corium into
Fibrocyte proliferation, increases skin elasticity, improves microcirculation.
Component and mass fraction in above-mentioned technical proposal, are that inventor screens determination by many experiments.Inventor
By the combination of collagen peptide, catechin, Gotu Kola P.E and EGF etc., can become striae of pregnancy
Narrow, desalination, realizes the preventing and treating of striae of pregnancy, but find that the stability of the combination is not good (with the extension of holding time, prevention effect
Substantially it is deteriorated), in this regard, inventor is by adding the vitamin C being adapted with combinations thereof on a small quantity to improve stability, so as to carry
The stable effect of skin care item high.
Preferably, the described skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：Collagen
2~8 parts of peptide, 2~5 parts of catechin, 2~4 parts of Gotu Kola P.E, 1~2 part of vitamin C, 0.5~2 part of EGF,
8~14 parts of vegetable oil, 1~4 part of cetearyl glucoside, 1~3 part of isopropyl myristate, ethylhexyl palmitate 1~3
Part, 2~4 parts of glycerine, 2~4 parts of cetostearyl alcohol, 1~3 part of propane diols, 0.1~0.5 part of preservative and 50~70 parts of water.
It is highly preferred that the described skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：Collagen egg
White 5 parts of peptide, 3 parts of catechin, 3 parts of Gotu Kola P.E, 1.5 parts of vitamin C, 1 part of EGF, 12 parts of vegetable oil, whale
2 parts of wax stearyl glucoside, 2 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 3 parts of glycerine, 3 parts of cetostearyl alcohol,
60 parts of 2 parts of propane diols, 0.5 part of preservative and water.
Preferably, the described skin care item for preventing and treating striae of pregnancy, also including 0.01~0.1 part of essence and/or chelating agent
0.05~0.5 part.Further, it is also possible to the compositions such as a small amount of amino acid, vitamin B are added on the basis of of the invention, but effect
Without the obvious change of generation.
Preferably, the mean molecule quantity of the collagen peptide is 800~1200 dalton.
Preferably, the vegetable oil is selected from one or more in SIMMONDSIA CHINENSIS SEED OIL, wheat-germ oil and olive oil.
Preferably, the preservative is selected from antibacterial peptide or the primary tortoise beetle ester of Buddhist nun.
Correspondingly, the present invention also provides the preparation method of the skin care item for preventing and treating striae of pregnancy, comprises the following steps：
S1 weighs vegetable oil, cetearyl glucoside, isopropyl myristate, ethylhexyl palmitate and cetearyl alcohol
Alcohol is stirred and heated to 75~85 DEG C in first reactor, obtains material A, is incubated standby；
S2 weighs glycerine, propane diols and water in second reactor, is stirred and heated to 75~85 DEG C, is slowly added to described
Material A, stirs homogeneous, obtains material B；
The material B is cooled to 35~40 DEG C by S3, weigh and add collagen peptide, catechin, Gotu Kola P.E,
Vitamin C, EGF and preservative, stir, cooling, obtain the skin care item for preventing and treating striae of pregnancy.
Preferably, the vegetable oil is selected from one or more in SIMMONDSIA CHINENSIS SEED OIL, wheat-germ oil and olive oil；It is described anti-
Rotten agent is selected from antibacterial peptide or the primary tortoise beetle ester of Buddhist nun.
Compared with prior art, beneficial effects of the present invention include：
(1) organic knot that the present invention passes through collagen peptide, catechin, Gotu Kola P.E and EGF etc.
Close, energy deep layer nourishes rough skin can promote cell growth, rebuild the destroyed fibre structures such as belly, promote collagen and fibre
The even synthesis and reparation of albumen, safety is gentle, improves crackle symptom, desalinates striae of pregnancy, realizes the preventing and treating of striae of pregnancy, improves skin
Skin elasticity；
(2) further, the present invention can reduce the loss of active component by adding a small amount of vitamin C, improve skin care item
Stable effect；
(3) consumption of collagen peptide, EGF and catechin isoreactivity composition is few, in enhancing prevention effect
Cost is reduced simultaneously, easy to use, required frequency of use is once a day, to improve the compliance of consumer；
(4) preparation method that the present invention is provided is simple, and obtained skin care item steady quality, prevention effect is good.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail.
In the present invention, involved component is conventional commercial product, or can be obtained by ordinary skill in the art means
.Collagen peptide is purchased from Shandong Long Bei bio tech ltd.
Embodiment one is used to prevent and treat the skin care item of striae of pregnancy
Skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：5 parts of collagen peptide, catechin 3
Part, 3 parts of Gotu Kola P.E, 1.5 parts of vitamin C, 1 part of EGF, 12 parts of vegetable oil, cetearyl glucoside 2
Part, 2 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 3 parts of glycerine, 3 parts of cetostearyl alcohol, 2 parts of propane diols, preservative
0.5 part and 60 parts of water.Vegetable oil is wheat-germ oil, and preservative is the primary tortoise beetle ester of Buddhist nun.
Preparation method for preventing and treating the skin care item of striae of pregnancy comprises the following steps：
S1 weighs vegetable oil, cetearyl glucoside, isopropyl myristate, ethylhexyl palmitate and cetearyl alcohol
Alcohol is stirred and heated to 82 DEG C in first reactor, obtains material A, is incubated standby；
S2 weighs glycerine, propane diols and water in second reactor, is stirred and heated to 82 DEG C, is slowly added to the material
A, stirs homogeneous 5min, obtains material B；
The material B is cooled to 38 DEG C by S3, weighs and add collagen peptide, catechin, Gotu Kola P.E, dimension life
Plain C, EGF and preservative, stir, cooling, obtain the skin care item for preventing and treating striae of pregnancy.
Embodiment two is used to prevent and treat the skin care item of striae of pregnancy
Skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：8 parts of collagen peptide, catechin 4
Part, 2 parts of Gotu Kola P.E, 1 part of vitamin C, 0.5 part of EGF, 14 parts of vegetable oil, cetearyl glucoside 2
Part, 3 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 2 parts of glycerine, 2 parts of cetostearyl alcohol, 3 parts of propane diols, preservative
0.5 part and 56 parts of water.Vegetable oil is olive oil, and preservative is the primary tortoise beetle ester of Buddhist nun.
Preparation method is with embodiment one.
Embodiment three is used to prevent and treat the skin care item of striae of pregnancy
Skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：3 parts of collagen peptide, catechin 4
Part, 4 parts of Gotu Kola P.E, 2 parts of vitamin C, 2 parts of EGF, 10 parts of vegetable oil, cetearyl glucoside 3
Part, 1 part of isopropyl myristate, 2 parts of ethylhexyl palmitate, 2 parts of glycerine, 2 parts of cetostearyl alcohol, 2 parts of propane diols, preservative
1 part and 62 parts of water.Vegetable oil is SIMMONDSIA CHINENSIS SEED OIL, and preservative is house fly antibiotic peptide.
Preparation method is with embodiment one.
Comparative example 1 is used to prevent and treat the skin care item of striae of pregnancy
Skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：5 parts of collagen peptide, allantoin 3
Part, 3 parts of Gotu Kola P.E, 1.5 parts of vitamin C, 1 part of EGF, 12 parts of vegetable oil, cetearyl glucoside 2
Part, 2 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 3 parts of glycerine, 3 parts of cetostearyl alcohol, 2 parts of propane diols, preservative
0.5 part and 60 parts of water.Vegetable oil is wheat-germ oil, and preservative is the primary tortoise beetle ester of Buddhist nun.
Comparative example 1 is with the difference of embodiment one：Containing etc. quality allantoin, without catechin.
Comparative example 2 is used to prevent and treat the skin care item of striae of pregnancy
Skin care item for preventing and treating striae of pregnancy, including following component and its mass fraction：5 parts of collagen peptide, catechin 3
Part, 3 parts of Gotu Kola P.E, 1.5 parts of vitamin B2,1 part of EGF, 12 parts of vegetable oil, cetearyl glucoside
2 parts, 2 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 3 parts of glycerine, 3 parts of cetostearyl alcohol, 2 parts of propane diols, anti-corrosion
60 parts of 0.5 part of agent and water.Vegetable oil is wheat-germ oil, and preservative is the primary tortoise beetle ester of Buddhist nun.
Comparative example 2 is with the difference of embodiment one：Containing etc. quality vitamin B2, without vitamin C.
The safety testing of test example one
With reference to 2015 editions of Ministry of Public Health's issue《Cosmetics health specification》In " human skin patch " related request
The embodiment of the present invention one to embodiment three, comparative example 1 to the skin care item of comparative example 2 are tested with assay method, is existed respectively
0h, 6h, 12h, 24h, 48h observe dermoreaction, and the experimental result of all trial volunteers is negative findings, skin do not occur
Adverse reaction.Therefore, it is gentle provided by the present invention for preventing and treating the skin care item safety of striae of pregnancy, it is nonirritant.
The striae of pregnancy preventive effect test of the skin care item of test example two
120 pregnant woman are convened to try out volunteer, it is desirable to which the age, at 22~35 years old, 3~4 months pregnant ages and gestation does not occur
Line, without conventional cosmetic allergic contact dermatitis history, is not used Tretinoin and glucocorticoid medicine in nearly 3 months.By pregnant woman volunteer with
Machine is divided into 6 groups, and every group 20, each group pregnant woman tries out embodiment respectively in aspect no difference of science of statistics such as age, pregnant age and body weight
The skin care of embodiment one, comparative example 1 and comparative example 2 after the first, the skin care item and normal temperature of comparative example 1 and comparative example 2 are preserved 1 year
Product, trial method：After every night cleans skin of abdomen, uniform application skin care item are once, continuous on probation 3 months.Often try out 1
Month, there is the number of striae of pregnancy in statistics each group pregnant woman, as a result as shown in table 1.
There is the demographics table of striae of pregnancy in the different group pregnant woman of table 1
| Group | Skin care item on probation | It is on probation 1 month | It is on probation 2 months | It is on probation 3 months |
| Group 1 | Embodiment one | 0 | 0 | 1 |
| Group 2 | Comparative example 1 | 0 | 2 | 7 |
| Group 3 | Comparative example 2 | 0 | 0 | 3 |
| Group 4 | Embodiment one after preserving 1 year | 0 | 0 | 2 |
| Group 5 | Comparative example 1 after preserving 1 year | 0 | 3 | 9 |
| Group 6 | Comparative example 2 after preserving 1 year | 0 | 4 | 12 |
As known from Table 1, the skin care item (group 1 and group 4) that the embodiment of the present invention one is provided play significant striae of pregnancy prevention
Effect, the pregnant woman for occurring striae of pregnancy after trying out 3 months is respectively 1 and 2, and two groups of difference in the reasonable scope, is illustrated often
There is no significant change in the quality after temperature is preserved 1 year；And the skin care item (group 2 and group 5) that comparative example 1 is provided can play certain pregnant
Be pregnent line preventive effect, but striae of pregnancy incidence is higher, it is on probation 3 months after there is striae of pregnancy pregnant woman be respectively 7 and 9, two
Group difference in the reasonable scope, illustrate normal temperature preservation 1 year after quality there is no significant change；The skin care that comparative example 3 is provided
Product (group 3 and group 6) can play preferable or certain striae of pregnancy preventive effect, occur pregnant woman's difference of striae of pregnancy after trying out 3 months
Be 3 and 12, group 6 striae of pregnancy incidence apparently higher than group 3, illustrate normal temperature preserve 1 year after quality there occurs substantially become
Change.The striae of pregnancy incidence of group 1 is only 5%, less than 35% incidence of group 2, less than 15% incidence of group 3.
The striae of pregnancy therapeutic effect test of the skin care item of test example three
90 puerperas are convened to try out volunteer, it is desirable to which the age, at 22~35 years old, obvious striae of pregnancy occurs, without conventional cosmetic
Product allergy history, is not used Tretinoin and glucocorticoid medicine in nearly 3 months.Puerpera volunteer is randomly divided into 3 groups, often
Group 30, each group puerpera tries respectively in aspect no difference of science of statistics such as age, body weight, abdominal pregnancy line length, width and colors
With embodiment one, the skin care item of comparative example 1 and commercially available striae of pregnancy frost, trial method：After every night cleans skin of abdomen,
Even smearing skin care item are once, continuous on probation 3 months.After on probation 3 months, the trial state of each group puerpera is counted, as a result such as the institute of table 2
Show.Therapeutic effect judgment criteria is as follows：It is effective：Striae of pregnancy is thin out and range shorter more than 50%；Effectively：Striae of pregnancy is thin out and model
Enclose diminution more than 20%；It is invalid：Striae of pregnancy is not thin out and range shorter 10% within.
The striae of pregnancy treatment table of the different group puerperas of table 2
| Group | It is effective | Effectively | It is invalid | Total effective rate |
| One group of embodiment | 6 | 19 | 5 | 83.3% |
| 1 group of comparative example | 1 | 16 | 13 | 56.7% |
| Commercially available group | 4 | 15 | 11 | 63.3% |
As known from Table 2, the skin care item that the embodiment of the present invention one is provided have significant striae of pregnancy therapeutic effect, total effective rate
Up to 83.3%, hence it is evident that higher than the 56.7% of 1 group of comparative example, also above commercially available group 63.3%.
In sum, the skin care item that the present invention is provided have good prevention and treatment effect, and safety temperature to striae of pregnancy
With it is easy to use.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to assert
Specific implementation of the invention is confined to these explanations.For general technical staff of the technical field of the invention,
On the premise of not departing from present inventive concept, some simple deduction or replace can also be made, should be all considered as belonging to of the invention
Protection domain.
Claims (9)
1. a kind of skin care item for preventing and treating striae of pregnancy, it is characterised in that：Including following component and its mass fraction：Collagen
2~10 parts of peptide, 1~5 part of catechin, 1~5 part of Gotu Kola P.E, 0.5~3 part of vitamin C, EGF 0.1~2
Part, 5~15 parts of vegetable oil, 1~5 part of cetearyl glucoside, 1~3 part of isopropyl myristate, ethylhexyl palmitate 1
40~70 parts of~3 parts, 1~5 part of glycerine, 1~4 part of cetostearyl alcohol, 1~3 part of propane diols, 0.1~1 part of preservative and water.
2. skin care item for preventing and treating striae of pregnancy according to claim 1, it is characterised in that：Including following component and its matter
Amount number：2~8 parts of collagen peptide, 2~5 parts of catechin, 2~4 parts of Gotu Kola P.E, 1~2 part of vitamin C, epidermis life
0.5~2 part of the factor long, 8~14 parts of vegetable oil, 1~4 part of cetearyl glucoside, 1~3 part of isopropyl myristate, palm
1~3 part of sour Octyl Nitrite, 2~4 parts of glycerine, 2~4 parts of cetostearyl alcohol, 1~3 part of propane diols, 0.1~0.5 part of preservative and
50~70 parts of water.
3. skin care item for preventing and treating striae of pregnancy described in claim 2, it is characterised in that：Including following component and its mass parts
Number：5 parts of collagen peptide, 3 parts of catechin, 3 parts of Gotu Kola P.E, 1.5 parts of vitamin C, 1 part of EGF, plant
12 parts of oil, 2 parts of cetearyl glucoside, 2 parts of isopropyl myristate, 2 parts of ethylhexyl palmitate, 3 parts of glycerine, spermaceti are hard
60 parts of 3 parts of lipidol, 2 parts of propane diols, 0.5 part of preservative and water.
4. skin care item for preventing and treating striae of pregnancy any one of claims 1 to 3, it is characterised in that：Also include essence
0.01~0.1 part and/or 0.05~0.5 part of chelating agent.
5. skin care item for preventing and treating striae of pregnancy any one of claims 1 to 3, it is characterised in that：The collagen egg
The mean molecule quantity of white peptide is 800~1200 dalton.
6. skin care item for preventing and treating striae of pregnancy any one of claims 1 to 3, it is characterised in that：The vegetable oil
Selected from one or more in SIMMONDSIA CHINENSIS SEED OIL, wheat-germ oil and olive oil.
7. skin care item for preventing and treating striae of pregnancy any one of claims 1 to 3, it is characterised in that：The preservative
Selected from antibacterial peptide or the primary tortoise beetle ester of Buddhist nun.
8. the preparation method for preventing and treating the skin care item of striae of pregnancy according to claim 1, it is characterised in that：Including as follows
Step：
S1 weigh vegetable oil, cetearyl glucoside, isopropyl myristate, ethylhexyl palmitate and cetostearyl alcohol in
In first reactor, 75~85 DEG C are stirred and heated to, obtain material A, be incubated standby；
S2 weighs glycerine, propane diols and water in second reactor, is stirred and heated to 75~85 DEG C, is slowly added to the material
A, stirs homogeneous, obtains material B；
The material B is cooled to 35~40 DEG C by S3, weighs and add collagen peptide, catechin, Gotu Kola P.E, dimension life
Plain C, EGF and preservative, stir, cooling, obtain the skin care item for preventing and treating striae of pregnancy.
9. the preparation method for preventing and treating the skin care item of striae of pregnancy according to claim 8, it is characterised in that：The plant
One or more from SIMMONDSIA CHINENSIS SEED OIL, wheat-germ oil and olive oil of grease separation；The preservative is selected from antibacterial peptide or Ni Baijin
Methyl esters.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710246943.6A CN106913485A (en) | 2017-04-16 | 2017-04-16 | A kind of skin care item for preventing and treating striae of pregnancy and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710246943.6A CN106913485A (en) | 2017-04-16 | 2017-04-16 | A kind of skin care item for preventing and treating striae of pregnancy and preparation method thereof |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519036A (en) * | 2017-09-06 | 2017-12-29 | 深圳肽之妃科技有限公司 | A kind of striae of pregnancy spray containing polypeptide and preparation method thereof |
| CN107802895A (en) * | 2017-12-08 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of scar repair material and its preparation method and application |
| CN109125173A (en) * | 2018-09-19 | 2019-01-04 | 李燕 | A kind of face cream and preparation method thereof removing striae of pregnancy |
| CN110934814A (en) * | 2019-12-06 | 2020-03-31 | 杭州恩格生物医疗科技有限公司 | Skin care essence containing stem cell active factors and application thereof |
| CN111631964A (en) * | 2020-06-17 | 2020-09-08 | 广州欧盛化妆品有限公司 | Striae gravidarum repair cream and preparation method thereof |
-
2017
- 2017-04-16 CN CN201710246943.6A patent/CN106913485A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107519036A (en) * | 2017-09-06 | 2017-12-29 | 深圳肽之妃科技有限公司 | A kind of striae of pregnancy spray containing polypeptide and preparation method thereof |
| CN107802895A (en) * | 2017-12-08 | 2018-03-16 | 广州赛莱拉干细胞科技股份有限公司 | A kind of scar repair material and its preparation method and application |
| CN109125173A (en) * | 2018-09-19 | 2019-01-04 | 李燕 | A kind of face cream and preparation method thereof removing striae of pregnancy |
| CN110934814A (en) * | 2019-12-06 | 2020-03-31 | 杭州恩格生物医疗科技有限公司 | Skin care essence containing stem cell active factors and application thereof |
| CN111631964A (en) * | 2020-06-17 | 2020-09-08 | 广州欧盛化妆品有限公司 | Striae gravidarum repair cream and preparation method thereof |
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Application publication date: 20170704 |