CN108175740A - It is a kind of that there is effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect and preparation method thereof - Google Patents
It is a kind of that there is effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect and preparation method thereof Download PDFInfo
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
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- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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Abstract
There is the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect the invention discloses a kind of, including following weight percent composition：'Heijialun ' seed oil 3~6%；Butyrospermum parkii fruit fat 2~4%；Olive oil 3~6%；Cocoa butter 2~4%；It dispels striae of pregnancy composition 117.5%~35%, striae of pregnancy composition 29%~22% of dispelling.Striae of pregnancy composition 1 wherein dispel by methyl-monosilane alcohol hydroxyproline ester aspartate 5%~10%；Collagen 2.5%~5%；Beta glucan 10%~20% forms；Striae of pregnancy composition 2 dispel by Pseudoalteromonas tunning extract 3%~10%；Acetyl group tripeptides 13%~6%；Gotu Kola P.E 2%~4%；Oligopeptides 11%~2% forms.The advantage of the invention is that：Effectively prevention and solves the problems, such as striae of pregnancy, scar fracture regeneration link and repair difficulty, allow the repair cream of its skin revitalization.The preparation method of the repair cream is also provided simultaneously.
Description
Technical field
The present invention relates to pregnant recovery technique field, and in particular to a kind of to have effectively prevention and pregrant abdominal stretch marks-removing effect
Repair cream and preparation method thereof.
Background technology
Striae of pregnancy is a kind of linear skin damage of the corium generated in pregnancy, clinically very universal, about
Striae of pregnancy can occur for the pregnant woman for having 50%-70%, between being usually happened at pregnancy 6 to 8 months.
Gestation skin can increase with uterus, and the expansion of subcutaneous tissue such as fat and muscle is drawn gradually and excessively
It stretches, leads to skin corium connective tissue damage, collagenous fibres and elastomer destroy, and affected area extensibility and elasticity is caused to weaken,
So as to generate the skin injury of striated.Breast, thigh etc. can also generate pregnancy period lines due to excessive tensile.
Meanwhile in pregnancy, huge variation can occur for the expression of pregnant woman's hormone in vivo receptor and hormonal readiness, gestation
Estrogen receptor expression amount at line doubles than normal skin, and the expression of receptor amount of androgen and glucocorticoid is also increased
Add, this is indicated that in the skin for bearing bigger mechanical strain position, active expression of hormonal receptors amount higher.Sugared cortical hormone
The surge of element can inhibit fibroblastic activity and proliferation, the elastic fibers and collagen for synthesizing fibroblast
It reduces, so as to hinder the completeness reparation for the connective tissue being destroyed in skin corium.
Originally striae of pregnancy becomes aubergine (immature or inflammation striae of pregnancy) from rose pink.Their face with the time
Color is changed to pearl white (ripe striae of pregnancy).They become less it is clear that but leave scar, these scars can be with
It is tiny and be difficult to notice, but they form dolly dimple sometimes so that skin has the appearance of fold..Striae of pregnancy is once sent out
Be born with is difficult to be eradicated, therefore the influence of great body and psychology is brought to patient.
The cause of disease of striae of pregnancy is still unclear at present, the change of mechanical tension and hormone in vivo that period of gestation skin is born at present
Change is considered as the main pathogenesis of striae of pregnancy, and also several factors take part in the generation of striae of pregnancy, development, these factors are still
It need to further study to confirm.
There are many method of the treatment striae of pregnancy of domestic and foreign literature report at present, mainly controlled including external medication, instrument
The effect for the treatment of, acupuncture therapy, combination therapy, but this all still some experimental treatment, various methods, still has dispute, mesh
It is preceding there is no one way to as treatment striae of pregnancy standard.
The processing method for the treatment of is substantially part：
External used medicine or skin care item treatment：
1.1 using the very small organic acids of glycolic equimolecular quantitys, can effective skin permeation, pass through keratinocyte
The cell factor of release adjusts the synthesis of collagen and the degradation of matrix, so as to play the role for the treatment of striae of pregnancy, if to play
The effect of chemical barking, then need that glycolic on probation is dense, and irritation is bigger, easily causes skin burn, needs
It to be tried out under physician guidance.The topical compounds of Tretinoin (all-trans vitamin A acid) or tartaric acid, can improve early pregnancy
The clinical manifestation of line, it is not good enough for late pregnancy line curative effect.
1.2 essential oil champignon methods, this method need interval procedure when repairing, and the course for the treatment of is long, generally requires 6~12 months, and
Height is required the technology of beautician, and best effect is only capable of making pregnant speckle desalination 20%.
Instrument therapy
2.1Relume photon pigment regeneration therapies：Its pigmentation by increasing striae of pregnancy, makes itself and surrounding normal skin
Skin color approaches, and so as to achieve the effect that hidden striae of pregnancy, and the institutional framework of striae of pregnancy is not made to change, therefore, should
Method can desalinate striae of pregnancy to a certain extent, but be definitely not the means for effecting a radical cure striae of pregnancy.
2.2 laser therapy：Damaged skin is made to come off by laser, this therapy dotted can only be treated, and large area needs by several times
Treatment, is not easy to grasp the depth.Easy skin ambustion, often understands scar.
2.3 crystallites grind skin therapy：By the method abraded skin of machinery, using epithelial tissue regeneration principle, in vacuum
By tiny grinding-material under situation, such as alundum (Al2O3) crystal, silica crystal etc., it is ejected into the therapy section of patient at a high speed
Position, pain can be brought to patient for large area treatment and there are scars, is not suitable for striae of pregnancy treatment.
It is directed to the defects of above-mentioned, the composition that those skilled in the art will more wish to put into skin surface improvement
On, it is expected to obtain relatively satisfied effect.
Chinese patent application CN 101152138 discloses a kind of cosmetic product with pregrant abdominal stretch marks-removing effect, includes sweet tea
The ingredients such as apricot kernel oil, olive oil, Gotu Kola P.E, small molecule broad bean polypeptide, the bionical peptide of epidermal growth factor and vitamin grain,
The bionical peptide of epidermal growth factor is wrapped up using nanometer technology, passes through Gotu Kola P.E and small molecule broad bean polypeptide, epidermis
The synergistic function of the various nutrients such as the bionical peptide of growth factor penetrates into the elastic fibrous tissue of skin, promotes skin collagen
Synthesis, restore skin vigor and elasticity, can weaken the width of striae of pregnancy, length and color, but repairing effect is still not enough managed
Think.
Chinese patent application CN 101791283 discloses a kind of cosmetics for eliminating striae of pregnancy and scar, prepares raw material
Including niacinamide, epithelical cell growth factor, vitamin B2, Asiaticoside, cupu oil and collagen etc., clinical repair statistics
Display has a preferable striae of pregnancy repairing effect, but epithelical cell growth factor, Asiaticoside, collagen and niacinamide use
It measures larger, causes cost higher, and required frequency of use is higher (3 times a day).
CN 201710182413.X disclose one kind except striae of pregnancy frost, including following weight percent raw material：Beta glucan
50-70%, glycerine 3-5%, jojoba seed oil 2-5%, vitamin E oil 2-5%, Butyrospermum parkii fruit fat 2-5%, olive oil 3-
7%th, Gotu Kola P.E 1-3%, notoginsenoside 0.2-1%, dipotassium glycyrrhizinate 0.1-1%.The advantageous effect of the invention is logical
Rational formula combination is crossed, each active ingredient is enable to quickly introduce dermal layer of the skin and accelerates skin repair, makes to form striae of pregnancy
Collagen fibers of skin and elastic fibers effectively repaired, while desalinate pigment, strengthen the moisture-keeping function to skin, for
The striae of pregnancy of the formation striae of pregnancy of especially 3 years or more dispels effect with good.
CN 201610738211.4 discloses a kind of cold cream for eliminating striae of pregnancy, which is characterized in that includes following weight
The raw material of number：10-15 parts of epithelical cell growth factor, 10-15 parts of kaempferol, methyl-monosilane alcohol hydroxyproline ester aspartic acid
5-10 parts of ester, 5-10 parts of vitamin A acid, 10-15 parts of collagen.The invention can eliminate striae of pregnancy desalination, and shorten and control
Treat the time.
CN201610972865.3 discloses a kind of bio protease new life essence cream.The invention includes acrylic acid (ester) class
Copolymer sodium, tocopherol acetate, asiaticosid, butanediol, niacinamide, lecithin, lactobionic acid, silver oxide, false Alteromonas
Bacterium tunning extract and Butyrospermum parkii fruit fat, above-mentioned composition by weight percentage, respectively 1%-5%, 1%-5%,
10%-20%, 0.5%-3%, 0.5%-3%, 10%-20%, 1%-5%, 0.5%-3%, 10%-30%, 10%-
25%；Remaining is solvent, the preferred deionized water of solvent.The invention has the function of to remove that acne, disappear print well, can anti-inflammatory stop
Bitterly, blackhead dark sore is removed, calms down scar, and excess oil and aging cutin layer are removed while unclogging, reduces acne
Regeneration promotes skin cell newborn, skin is made to radiate vigour and gloss, and can reduce skin susceptibility simultaneously, avoids skin not
It is suitable.
CN201510044263.7 discloses a kind of Essence and its system containing chitosan oligomer and jellyfish collagen albumen
Into facial mask, which obtains after being mixed by following component：Chitosan oligomer, jellyfish collagen albumen, lecithin, hydroxyl dried meat ammonia
Ester silanol, hydroxy ethyl cellulose, xanthan gum, purslane extract, glycerine, butanediol, Phenoxyethanol, Sensiva SC50
And water.It being capable of moisture-keeping crease-shedding, reparation skin.
CN201710147627.3 discloses a kind of striae of pregnancy and repairs essence composition, it is characterised in that：According to dosage part hundred
Divide than meter, including following components：Emulsifier：1-2, water：Surplus, glycerine：5-6, moisturizer：5-7, striae of pregnancy repair compound：
5-7, beta glucan：2-3, counter-stimulus：0.1, preservative：0.1-0.2, essence：0.01‐0.02；Wherein, striae of pregnancy reparation
It closes object and includes Pseudoalteromonas tunning extract and acetyl group tripeptides -30.Its material composition pharmacological property is mild, and effect is bright
Aobvious, non-stimulated, without side-effects, striae of pregnancy patient can be safe to use.
The drawbacks such as the undesirable universality of reparation generally existing repairing effect of above-mentioned various postpartum striaes of pregnancy and scar is bad.
Invention content
There is the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect the object of the present invention is to provide a kind of, which leads to
Cross methyl-monosilane alcohol hydroxyproline ester aspartate, Pseudoalteromonas tunning extract, centella
(CENTELLAASIATICA) composition of a variety of active ingredients such as extract mutually acts synergistically, so as to reach effectively solve it is pregnant
Be pregnent line, scar fracture regeneration link and repair, allow the repair cream of its skin revitalization.The preparation side of the repair cream is also provided simultaneously
Method.
The concrete scheme of the present invention is as follows：It is a kind of that there is the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, including such as
Lower weight percent composition：
'Heijialun ' seed oil 3~6%；
Butyrospermum parkii fruit fat 2~4%；
Olive oil 3~6%；
Cocoa butter 2~4%；
Methyl-monosilane alcohol hydroxyproline ester aspartate 5~10%；
Pseudoalteromonas tunning extract 3~10%；
Acetyl group tripeptides -1 3~6%；
Collagen 2.5~5%；
Gotu Kola P.E 2~4%；
Oligopeptides -1 1~2%；
Beta glucan 10~20%.
Methyl-monosilane alcohol hydroxyproline ester aspartate 5%~10%；Collagen 2.5%~5%；Beta glucan
10%~20% forms striae of pregnancy composition 1 of dispelling；Pseudoalteromonas tunning extract 3%~10%；Acetyl group tripeptides-
1 3%~6%；Gotu Kola P.E 2%~4%；Oligopeptides -1 1%~2% forms striae of pregnancy composition 2 of dispelling.
It should be noted that：The Pathological Physiology of comprehensive striae of pregnancy, main triggering factors be inflammation, mechanical stretching and
Hormonal milieu, therefore, prevention and reduction striae of pregnancy product are needed from the following aspects collective effect：
1st, it maintains and repairs epidermal cell barrier；
2nd, targeting is in fibroblast：It can be proliferated and be stimulated metabolism, particularly shadow by active cell
The new synthesis of the main macromolecular (collagen and elastin laminin) of skin elasticity and tension is rung to play a role；
3rd, improve skin collagen activity；
4th, dermal layer of the skin is promoted to rebuild；
5th, the fracture of mechanical stretching skin fiber and the inflammation destroyed etc. are eliminated.
The expression of " prevention of striae of pregnancy on skin " means following effect：In in terms of the cosmetology, by being known to draw
Play the event that striae of pregnancy occurs, such as gestational period, before or during using the composition, make to avoid or at least reduce striae of pregnancy
Formation possibility, that is to say, that reduce length, width and/or the depth of striae of pregnancy.
Therefore the proposition of above-mentioned composition is based primarily upon following principle：
1st, it maintains and repairs epidermal cell barrier:A kind of crude vegetal oil/fat composition
The more other oils of vitamin type and quantity contained by olive oil are significantly more, and such as wherein vitamin A (and A is former) has
Play the role of making skin smooth, delicacy and increase its elasticity, vitamin B1 has the function of to flatten skin fine corrugations, vitamin
C has the effects that enhance vessel wall elasticity, expands blood flow；And coordinate the active function of vitamin E oil inhibition tyrosinase,
The generation of melanin can be effectively reduced；
Butyrospermum parkii fruit fat has effects that promote skin regeneration, prevents light aging, to suffering from dermatitis, sunburn and scar
Skin has apparent promotion Healing.There are good long-term moistening effect, its spreadability and transdermal suction to the surface layer of skin
The property received is all fairly good, especially suitable for without greasy formula, epidermis is moistened in stimulation of releiving.
Cocoa butter contains relatively rich phenol, have excellent anti-oxidation function, be used for a long time, peomote skin elasticity and
Heal the skin being chapped from the cold, and so as to prevent striae of pregnancy, treats the skin being chapped from the cold.
'Heijialun ' seed oil is a kind of good vegetable oil extracted from ' Heijialun ' seed, containing γ needed by human-
A variety of unrighted acids such as leukotrienes Gamma-Linoleic acid.Gamma-Linolenic acid is unique -6 aliphatic acid of omega,
There is good repair to skin barrier.
2nd, promote or enhance fibroblast proliferation with connecting
Pseudoalteromonas tunning extract：Enhance the connection of human fibroblasts, promote keratinocyte
Growth, the connection of enhancing skin and structural remodeling, the synthesis of induced skin albumen, enhancing extracellular medium (ECM).Cooperate with acetyl group three
Peptide -1：Inhibit people MMPs activity, prevent ECM ingredient degradations.
Epidermal growth factor (oligopeptides -1)：It is naturally occurring in human body, multi-signal albumen in Skin Cell can be activated, promote
Into the wound repair and normal growth of skin histology, neoblast shared ratio in skin is improved, increases cytoplasm, promotes
Skin corium fibroblast proliferation increases skin elasticity, improves microcirculation.
3rd, improve skin collagen activity
Collagen peptide is obtained by collagen or gelatin through enzymolysis, and molecular weight is normally no higher than 3000 dalton.The present invention's
The molecular weight of collagen peptide is relatively low (being less than 1500 dalton), conducive to absorption, can supply skin histology and structure nutritional ingredient,
Increase skin hydratability, improve Skin Cell environment, make the collagen increased activity in skin, promote the new of skin histology
Old metabolism
4th, dermal layer of the skin is promoted to rebuild
In skin corium extracellular matrix reticular structure, hydroxyl dried meat urethane silanol passes through the mucopolysaccharide and egg with skin corium
White polysaccharide combines, and supports the reticular structure of skin corium.
5th, the fracture of mechanical stretching skin fiber and the inflammation destroyed etc. are eliminated.
6th, centella (CENTELLA ASIATICA) extract promotes collagen synthesis, eliminates collagenous fibres and elasticity
Inflammation caused by fiber destruction, the asiaticoside in centella (CENTELLA ASIATICA) extract can promote I type glue
The synthesis of former albumen, while madecassoside can dramatically increase the synthesis of type III collagen.Type III collagen is
The main constituents of the extracellular matrix of various internal organs and skin, centella (CENTELLA ASIATICA) extract
There is splendid reparation skin inflammation.
In the above-mentioned repair cream with effective prevention and pregrant abdominal stretch marks-removing effect, the collagen molecules amount is low
In 1500 dalton.
In the above-mentioned repair cream with effective prevention and pregrant abdominal stretch marks-removing effect, further include：
The water of suitable moisturizer and emulsifier and surplus.
In the above-mentioned repair cream with effective prevention and pregrant abdominal stretch marks-removing effect, the moisturizer is glycerine, 1,2
One or two kinds of combinations in hexylene glycol；The emulsifier is M68.
In the above-mentioned repair cream with effective prevention and pregrant abdominal stretch marks-removing effect, further include：
Suitable preservative and antioxidant.
It should be noted that of the present invention refer to the amount added according to the usage of trade in right amount, in the art, it is
Routine techniques, in this regard, the present invention does not do and more specifically limits.
In the above-mentioned repair cream with effective prevention and pregrant abdominal stretch marks-removing effect, the preservative is methyl esters or benzene
One or two kinds of combinations in oxyethanol；The antioxidant is combinations one or two kinds of in vitamin E and fragrant acyl ketone.
Another object of the present invention be to provide it is a kind of have as described above effectively prevent and dispel striae of pregnancy work(
The preparation method of the repair cream of effect, includes the following steps：
S1, A phase materials are mixed, mixing condition is 70-85 DEG C, stirs 20-35min, obtains water phase and keep the temperature；Described
A phase materials include water and at least part moisturizer；
S2, by B phase materials mix, mixing condition be 70-85 DEG C, stir 25-35min, obtain oil phase and keep the temperature；Described
It is anti-oxidant that B phase materials include emulsifier, 'Heijialun ' seed oil, Butyrospermum parkii fruit fat, olive oil, cocoa butter and at least part
Agent and at least part preservative；
S3, vacuumize, B phases be pumped into A phases, start homogenizer, homogeneous for a period of time after, keep the temperature 10 minutes；
S4, after being cooled to 50 DEG C, each raw material of C phases is sequentially added, is stirred evenly；C phase materials include：Methyl-monosilane alcohol hydroxyl
Proline ester aspartate, Pseudoalteromonas tunning extract, acetyl group tripeptides -1, collagen, centella carry
Take object, oligopeptides -1, beta glucan；
S5,45 DEG C are cooled to, sequentially add each raw material of D phases, stir evenly, discharged after appearance and pH qualifieds；Institute
The D phase materials stated include remaining antioxidant, remaining moisturizer and remaining preservative.
The present invention is had the following advantages relative to the prior art and effect：
The formula of the present invention has a feather in one's cap in terms of striae of pregnancy size reduction and color aufhellung.
Specific embodiment
With reference to embodiment, the invention will be further described, but does not form any limitation of the invention, any
In the modification for the limited number of time that scope of the invention as claimed is made, still in scope of the presently claimed invention.
Embodiment 1-3
The reagents and materials used in the present invention are commercially available；
Repair cream preparation method with effective prevention and pregrant abdominal stretch marks-removing effect is as follows：
S1, the raw material for weighing above-mentioned weight percent；
S2, A phase materials are mixed, mixing condition is 70-85 DEG C, stirs 20-35min, obtains water phase and keep the temperature；
S3, by B phase materials mix, mixing condition be 70-85 DEG C, stir 25-35min, obtain oil phase and keep the temperature；
S4, -0.04mPa is evacuated to, B phases is pumped into A phases, start homogenizer, fast homogeneous after five minutes, keeps the temperature 10 points
Clock；
S5,50 DEG C, sequentially add each raw material of C phases, stir evenly；
S6,45 DEG C, sequentially add each raw material of D phases, stir evenly, discharge after appearance and pH qualifieds.
Above-mentioned formula such as table 1：
The formula table of table 1 embodiment 1-3 and comparative example 1-5
Performance test
Except striae of pregnancy frost, (component is pure cupu oil to the present invention, vitamin e, elastin laminin, glue with the frost of certain striae of pregnancy on the market
Former albumen, shea butter), it is removed (striae of pregnancy length, width and color) etc. from striae of pregnancy prophylactic tria and new and old striae of pregnancy
Using effect is compared.
1st, striae of pregnancy prophylactic tria
It gives birth to for the first time：
Use groups：Age is the pregnant mother of 22-31 Sui
Usage time：A third that is pregnant month extremely fertility the latter moon
Application method：Above-described embodiment, comparative example and commercially available striae of pregnancy frost are distributed to 100 pregnant mothers in abdomen respectively
Massage uses, 1 times/day of frequency of use, usage amount 5-10g/ times.
Clinical judgment criteria：Assess three items such as striae of pregnancy entirety severity, striae of pregnancy color, striae of pregnancy slackness
Mesh, while scored (0-5 points) using 6 point-scores：0 point represents perfect state, and 5 points represent severe conditions.
Use result such as the following table 2：
2 striae of pregnancy prophylactic tria result table of table
2nd, new and old striae of pregnancy removal
Postpartum：
Use groups：The mother given birth to has newborn striae of pregnancy, age 22-31 Sui
Usage time：It uses 3 months
Application method：Abdomen is divided into two regions by subject using ventrimeson as boundary, is chosen wherein by random principle
Side uses position as 1 product of embodiment, and opposite side is as control position.Each side draw is fresh and severity is similar one
Place's striae of pregnancy is marked, and carries out the clinical of target skin lesion and judges.By above-described embodiment and comparative example and embodiment and commercially available gestation
Line frost is distributed to 100 subjects and is used in abdominal massaging respectively, 1 times/day of frequency of use, usage amount 5-10g/ times.
Clinical judgment criteria：Assessment striae of pregnancy is integrally repaired, striae of pregnancy area, striae of pregnancy color, striae of pregnancy slackness etc.
Four projects, while scored (0-5 points) using 6 point-scores：5 points represent perfect state, and 0 point represents severe conditions.
Use result such as table 2：
2 embodiment 1 of table and the removal test result comparison of the new and old striae of pregnancy of commercial like product and comparative example
By above-mentioned experimental result can be seen that the present invention formula can be effectively improved striae of pregnancy integrally repair situation,
Striae of pregnancy area, striae of pregnancy color, striae of pregnancy slackness.
Above-described embodiment is the preferable embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, other any Spirit Essences without departing from the present invention with made under principle change, modification, replacement, combine, simplification,
Equivalent substitute mode is should be, is included within protection scope of the present invention.
Claims (7)
1. a kind of have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that including following weight percent
Component：
'Heijialun ' seed oil 3~6%；
Butyrospermum parkii fruit fat 2~4%；
Olive oil 3~6%；
Cocoa butter 2~4%；
Methyl-monosilane alcohol hydroxyproline ester aspartate 5~10%；
Pseudoalteromonas tunning extract 3~10%；
Acetyl group tripeptides -1 3~6%；
Collagen 2.5~5%；
Gotu Kola P.E 2~4%；
Oligopeptides -1 1~2%；
Beta glucan 10~20%.
2. according to claim 1 have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that described
Collagen molecules amount be less than 1500 dalton.
3. according to claim 1 have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that
It further includes：
The water of suitable moisturizer and emulsifier and surplus.
4. according to claim 3 have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that described
Moisturizer for glycerine, one or two kinds of combinations in 1,2 hexylene glycols；The emulsifier is M68.
5. according to claim 1 have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that also wraps
It includes：
Suitable preservative and antioxidant.
6. according to claim 5 have the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect, which is characterized in that described
Preservative be combinations one or two kinds of in methyl esters or Phenoxyethanol；The antioxidant is in vitamin E and fragrant acyl ketone one
Kind or two kinds of combinations.
7. a kind of preparation side with the effectively repair cream of prevention and pregrant abdominal stretch marks-removing effect as described in claim 1-6 is any
Method, which is characterized in that include the following steps：
S1, A phase materials are mixed, mixing condition is 70-85 DEG C, stirs 20-35min, obtains water phase and keep the temperature；The A phases
Material includes water and at least part moisturizer；
S2, by B phase materials mix, mixing condition be 70-85 DEG C, stir 25-35min, obtain oil phase and keep the temperature；The B phases
Material includes emulsifier, 'Heijialun ' seed oil, Butyrospermum parkii fruit fat, olive oil, cocoa butter and at least part antioxidant
With at least part preservative；
S3, vacuumize, B phases be pumped into A phases, start homogenizer, homogeneous for a period of time after, keep the temperature 10 minutes；
S4, after being cooled to 50 DEG C, each raw material of C phases is sequentially added, is stirred evenly；C phase materials include：Methyl-monosilane alcohol hydroxyl dried meat ammonia
Acid esters aspartate, Pseudoalteromonas tunning extract, acetyl group tripeptides -1, collagen, Gotu Kola P.E,
Oligopeptides -1, beta glucan；
S5,45 DEG C are cooled to, sequentially add each raw material of D phases, stir evenly, discharged after appearance and pH qualifieds；The D
Phase materials include remaining antioxidant, remaining moisturizer and remaining preservative.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201810082053.0A CN108175740B (en) | 2018-01-29 | 2018-01-29 | Repair cream with effects of effectively preventing and removing striae gravidarum and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810082053.0A CN108175740B (en) | 2018-01-29 | 2018-01-29 | Repair cream with effects of effectively preventing and removing striae gravidarum and preparation method thereof |
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| CN108175740A true CN108175740A (en) | 2018-06-19 |
| CN108175740B CN108175740B (en) | 2020-11-10 |
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| CN201810082053.0A Active CN108175740B (en) | 2018-01-29 | 2018-01-29 | Repair cream with effects of effectively preventing and removing striae gravidarum and preparation method thereof |
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| CN110013447A (en) * | 2019-03-13 | 2019-07-16 | 广州雅纯化妆品制造有限公司 | A kind of cream and preparation method thereof for dispelling striae of pregnancy |
| CN110314127A (en) * | 2019-08-23 | 2019-10-11 | 杭州千岛湖蓝色天使实业有限公司 | One kind is dispelled striae of pregnancy essence cream and preparation method thereof |
| CN113332193A (en) * | 2021-05-20 | 2021-09-03 | 广州天然国度生物科技有限公司 | Composition and massage cream for preventing stretch marks |
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| CN108175740B (en) | 2020-11-10 |
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