CN107496244A - A kind of natural plant essence liquid and preparation method thereof - Google Patents
A kind of natural plant essence liquid and preparation method thereof Download PDFInfo
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- CN107496244A CN107496244A CN201710829594.0A CN201710829594A CN107496244A CN 107496244 A CN107496244 A CN 107496244A CN 201710829594 A CN201710829594 A CN 201710829594A CN 107496244 A CN107496244 A CN 107496244A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
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Abstract
The present invention relates to cosmetic technical field, especially a kind of natural plant essence liquid and preparation method thereof, including deionized water, baeckea frutescen extraction concentrated essence liquid, baeckea frutescen essential oil, Rosa Damascana, beeswax, saualane, glycerine, polyoxyethylene carboxylate, cocoyl glucoside, isopropyl hexadecanoate, Sweet Almond Oil, median chain triglyceride oil, isomery dodecane, isopropyl myristate, lauryl alcohol, methyl oleate, Glycerin, mixed triester with caprylic acid capric acid, eugenol, benzene oxygen second, palmityl alcohol.A kind of natural plant essence liquid provided by the invention and preparation method thereof, it make use of the essential oil and extract solution of baeckea frutescen, the active ingredient of baeckea frutescen plant is sufficiently extracted, obtained skin care item, there is good antibacterial, inflammation-diminishing function to skin, and there is no excitant, play good skin care effect.
Description
Technical field
The present invention relates to cosmetic technical field, is a kind of Essence and preparation method thereof, especially a kind of natural plants
Essence and preparation method thereof.
Background technology
With the continuous improvement of living standard, maintenance of the people to healthy especially skin is increasingly taken seriously.Skin
Tissue is human body maximum tissue organ, is covered in human body surface, all harmful substances of barrier nature are to caused by viable organism
Detrimental effect.But with the increase at age, the gradual aging of function of skin histology organ, from the point of view of Aesthetic View, have a strong impact on
Enthusiasm of the people to life；From the point of view of physiology, effective protection of human internal organs is influenceed.The main original of skin aging
Because being that the various quantity of nutrient matter and quality needed in metabolic processes can not obtain physiology sexual satisfaction from diet,
So as to cause the quantity of the synthesis material of the life inhereditary material carrier DNA in life cells core to gradually decrease, it is ultimately resulted in
The kinds of protein and quantity for adjusting empty synthesis are reduced, and cellular metabolic activity declines therewith, and the life-span shortens relatively.The excessive aging of skin
The performance of phenomenon is：Cutis laxa, wrinkle increase intensification, pore increase, the thicker turmoil of dermatoglyph, skin elasticity decline etc..
At present, the most moisturizing of product for skin care on the market, limited efficacy.And natural plants can effectively achieve this mesh really
's.
As a kind of natural plants, baeckea frutescen has a variety of medical values, for example with dispelling wind and eliminating dampness, removing toxic substances, diuresis, stops
Bitterly, it is antipruritic to wait medical value, also there is the skin-protecting functions such as treatment eczema, pemphigus, the ringworm of the foot.
In traditional medicine adornment skin care item, it is typically necessary and adds the chemical agents such as antibacterial and sterilization, anti-inflammatory, to prevent skin
Disease, there is certain excitant to skin.
The medicine adornment skin care item of plant extracts have been engendered now, are mainly extracted effective components in plants, are utilized plant
The natural active principle of thing, reduces the excitant to skin.Plants essential oil has its unique composition and bioactivity, thus it
Medicine, antibacterial, cosmetics, additive etc. all have been widely used.But in plant extract, simply extract wherein essential oil
Partial active ingredient, plant medical value itself is not made full use of.Such as baeckea frutescen, presently mainly extract effective ingredient and add
To utilize.
The content of the invention
It is an object of the invention to provide a kind of skin care item for making full use of baeckea frutescen medical value.
To achieve the above object, the technical solution adopted by the present invention is：
A kind of natural plant essence liquid, by following material by weight：10 parts of deionized water, baeckea frutescen extraction are dense
Contracting Essence 15-19 parts, baeckea frutescen essential oil 6-9.7 parts, Rosa Damascana 2-18 parts, beeswax 2-10 parts, saualane 3-15 parts, glycerine
6.5-8.8 parts, polyoxyethylene carboxylate 2.3-4.3 parts, cocoyl glucoside 1.6-3.2 parts, isopropyl hexadecanoate 1.4-
2.1 parts, Sweet Almond Oil 1.3-2.2 parts, median chain triglyceride oil 1.5-2.8 parts, isomery dodecane 0.2-0.5 parts, myristic acid
Isopropyl ester 0.6-1.4 parts, lauryl alcohol 0.7-1.3 parts, methyl oleate 0.1-0.3 parts, Glycerin, mixed triester with caprylic acid capric acid 0.1-0.3 parts, fourth
Fragrant phenol 0.15-0.25 parts, Phenoxyethanol 0.1-0.4 parts, palmityl alcohol 0.1-0.4 parts.
Its preparation method of the natural plant essence liquid, comprises the following steps：
(1) part deionization (amounts of most half, preferably shorter than half) is taken, Rosa Damascana, beeswax, angle are taken according to formula
Shark alkane, cocoyl glucoside, isopropyl myristate, lauryl alcohol, eugenol, Phenoxyethanol, palmityl alcohol are scattered in deionization
In water, it is thoroughly mixed to have obtained basic mixed liquor；
(2) by polyoxyethylene carboxylate, isomery dodecane, isopropyl hexadecanoate, median chain triglyceride oil, oleic acid first
After ester weighs according to formula, it is added in above-mentioned mixed liquor, and carries out heating water bath；
Wherein, saualane and isomery dodecane are respectively using an inventive point for being the present invention, although because both are changing
Similar effect is played in cosmetic, in the prior art also it is few both share, reason is the effect that both are superimposed together
Fruit is simultaneously good not as effect is used alone, but it is surprisingly found by the inventors that, the step of by having been used saualane first (1)
" basic mixed liquor ", isomery dodecane is then used alone again and continues waters mixing in the step (2), can so cause angle
Shark alkane is surrounded without being had an effect with isomery dodecane by several esters, and can play a part of the lubrication of difference, moisturizing；
(3) baeckea frutescen essential oil, Sweet Almond Oil, be mixed to get mixed oil liquid；
Wherein described baeckea frutescen essential oil, obtained from business procurement.
(5) glycerine, Glycerin, mixed triester with caprylic acid capric acid and remaining deionized water mixing, and carry out heating water bath obtain glycerine mixing it is molten
Liquid；
(6) mixed oil liquid is added drop-wise in glycerine mixed solution, and is stirred, and after stirring 10~30 minutes, is sequentially added
Basic mixed liquor and baeckea frutescen extraction concentrated essence liquid stirs, and produces natural plant essence liquid.
Wherein, baeckea frutescen extraction concentrated essence liquid, preparation method include procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, then
It is put into hydrogen peroxide and is cleaned and sterilized again, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, is dried to moisture content below 5%, then will drying
Branch crush, the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and carries out enzyme 4.5~6.5
Solution, it is incubated 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the appearance of sealing is put into together
In device, heating water bath, the temperature of heating is 35-40 DEG C, after being incubated 6-8 hours, is being heated up to 60-65 DEG C simultaneously, stirring is peeled off
20 minutes；
(6) solution after being peeled off with the filter membrane of 500 mesh to stirring filters, after slag-liquid separation, the use of filter residue again
Alcohol solution dipping, filtering, the filtrate being filtrated to get twice merge；
(7) filtrate is put into container, and for heating water bath to 50-60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen
Essential oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, will remove baeckea frutescen essence
Filtrate pressurization after oil, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate high pressure aperture is saturating
Cross the trapped fluid of liquid and high pressure aperture；
(10) extract solution is concentrated, amalgamation liquid concentration extracts concentrated essence liquid until baeckea frutescen.
Wherein, the method in described step (5) can obtain the extraordinary product of effect, but pass through inventor
Long-term improvement and experiment, obtained a kind of more preferred method, be the present invention an inventive point, it is specific as follows：According to
Per 100kg ultra micro baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, it is put into together in the container of sealing, heating water bath,
The temperature of heating is 35-40 DEG C, after being incubated 6-8 hours, is being heated up to 60-65 DEG C simultaneously, and stirring is peeled off 20 minutes；Wherein, water
Bathe heating time and mode further refine, the active ingredient of baeckea frutescen powder can be caused it is further proposed that, that is, the temperature heated
For 35 degree of wait 1-2 hours, 40 DEG C are then risen within 1-2 minutes, after being incubated 4-7 hours, in 5 minutes, is heated up to 60
DEG C kept for 5 minutes, 65 DEG C are then heated within 1-2 minutes and is kept for 10 minutes, it is a kind of within this 20 minutes time to keep stirring
Mix.The final products of the step of have passed through improvement (5), by 6 groups, the Blind Test of every group of 15 people, the concentration of fragrance matter improves
2.3%.
Put into practice for many years in addition, inventor passes through, obtained following processing step, i.e., between step (9) and step (10),
Can also preferably, increase a silica gel column chromatography the step of, step is as follows：By high pressure aperture permeate, through silica gel column chromatography
Vacuum state infiltration absorption, obtains eluent, then merges eluent with the trapped fluid of high pressure aperture, obtain extract solution；Obtain
Extract solution it is extremely high in purity, and due to being physical method, can't have any shadow to the quality of product in itself
Ring, still, inventor has found in multiple experimentation, due in the work by " silica gel column chromatography vacuum state infiltration absorption "
When skill, have very more polar molecules and remain in silicagel column, this also often use this suction in this area
Subsidiary formula method carries out precious raw material disposal, because having very big loss late, causes production cost to sharply increase, the present inventor
By constantly research and development and practice, preferred method is obtained, this method can be reduced because polar molecule adsorption silica gel post
It is loss to cause so that production cost reduces, and specific way is as follows：Firstly, it is necessary to the use environment of the silicagel column to using is entered
Row transformation, preferable silica gel are pH value 6.5-6.9 (consistent with baeckea frutescen extract solution, to avoid that neutralization reaction occurs), and moisture is less than
3%, specific surface area is 320-350 square metres every gram；Before by this technique, high pressure aperture permeate is heated to 70-78
Degree Celsius, such benefit is on the premise of avoiding the volatilization of volatility effect material, silicagel column to be passed through more quickly, by above-mentioned two
The setting of individual key technology point so that final loss of effective components rate substantially reduces, while can effectively go the removal of impurity.
By detection, cymol (English：P-Cymene content) improves 0.036%, pulls aromatic content and carries
It is high by 0.012%.
Further, since the extract that the inventive method step (10) obtains has the taste of some slant acidities, although very light,
It it is the problem of as cosmetic field being still one very big, inventor has found to add the green tea extraction of 0.02-0.035 parts by weight
The kudzu root extract of thing and 0.06-0.075 parts by weight, this is the vast improvement of the present invention so that product of the present invention is specific
Fresh taste, the slightly pungent taste in baeckea frutescen extract is got rid of, final products have very pure and fresh taste, and
Has the effect of improving a lot for the shelf-life., can be with it is highly preferred that add the propane diols of 0.001-0.0015 parts by weight simultaneously
Preferably so that green-tea extract merges with final extract, inventor tests general ten several fusion agents, the effect of propane diols
Fruit is optimal.Preferably, green-tea extract uses commercially available product, and wherein kudzu root extract requires that the root of kudzu vine is always yellow
The standard of ketone (totalflavon) 80%.
The product of the present invention, in actual use, optimally, the use of eye mask substrate liquid is configured to, it is specific to use
Method is as follows：The water-soluble collagen of convention amount is added in Essence, the viscosity of eye mask substrate liquid is 2.3 × 10-3~
3.4×10-3Pa·s.It mitigates for the wrinkle of eye part skin and prevents allergic reaction to have extraordinary effect.
A kind of natural plant essence liquid provided by the invention and preparation method thereof, make use of the essential oil and extract solution of baeckea frutescen,
The active ingredient of baeckea frutescen plant is sufficiently extracted, obtained skin care item, there is good antibacterial, anti-inflammatory work(to skin
Can, and there is no excitant, play good skin care, especially eye part skin and act on.
Embodiment
In order to deepen the understanding of the present invention, with reference to embodiment, the invention will be further described, and the embodiment is only
For explaining the present invention, it is not intended to limit the scope of the present invention..
Embodiment 1
A kind of natural plant essence liquid, by following material by weight：10 parts of deionized water, baeckea frutescen extraction are dense
16.7 parts of contracting Essence, 8 parts of baeckea frutescen essential oil, 18 parts of Rosa Damascana, 6 parts of beeswax, 3 parts of saualane, 8.8 parts of glycerine, fatty acid polyglycol
4 parts of oxygen vinyl acetate, 3.2 parts of cocoyl glucoside, 1.6 parts of isopropyl hexadecanoate, 2.2 parts of Sweet Almond Oil, the acid of medium chain triglyceride three
1.5 parts of ester, 0.5 part of isomery dodecane, 0.6 part of isopropyl myristate, 1 part of lauryl alcohol, 0.2 part of methyl oleate, pungent capric acid
0.2 part of glyceride, 0.15 part of eugenol, -0.4 part of Phenoxyethanol, 0.1 part of palmityl alcohol.
Its preparation method of the natural plant essence liquid, comprises the following steps：
(1) part deionization is taken, Rosa Damascana, beeswax, saualane, cocoyl glucoside, myristic acid are taken according to formula
Isopropyl ester, lauryl alcohol, eugenol, Phenoxyethanol, palmityl alcohol are scattered in deionized water, are thoroughly mixed to have obtained basis
Mixed liquor；
(2) by polyoxyethylene carboxylate, isomery dodecane, isopropyl hexadecanoate, median chain triglyceride oil, oleic acid first
After ester weighs according to formula, it is added in above-mentioned mixed liquor, and carries out heating water bath；
(3) baeckea frutescen essential oil, Sweet Almond Oil, be mixed to get mixed oil liquid；
(5) glycerine, Glycerin, mixed triester with caprylic acid capric acid and remaining deionized water mixing, and carry out heating water bath obtain glycerine mixing it is molten
Liquid；
(6) mixed oil liquid is added drop-wise in glycerine mixed solution, and is stirred, and after stirring 10~30 minutes, is sequentially added
Basic mixed liquor and baeckea frutescen extraction concentrated essence liquid stirs, and produces natural plant essence liquid.
Embodiment 2
A kind of natural plant essence liquid, by following material by weight：10 parts of deionized water, baeckea frutescen extraction are dense
15 parts of contracting Essence, 6 parts of baeckea frutescen essential oil, 2 parts of Rosa Damascana, 2 parts of beeswax, 6.5 parts of saualane, 7 parts of glycerine, aliphatic acid polyoxy second
4.3 parts of alkene ester, 2 parts of cocoyl glucoside, 2.1 parts of isopropyl hexadecanoate, 1.3 parts of Sweet Almond Oil, median chain triglyceride oil 2
Part, 0.4 part of isomery dodecane, 1.4 parts of isopropyl myristate, 1.3 parts of lauryl alcohol, 0.1 part of methyl oleate, pungent capric acid glycerine
0.3 part of ester, 0.22 part of eugenol, 0.3 part of Phenoxyethanol, 0.2 part of palmityl alcohol.
Its preparation method of the natural plant essence liquid is same as Example 1.
Embodiment 3
A kind of natural plant essence liquid, by following material by weight：10 parts of deionized water, baeckea frutescen extraction are dense
19 parts of contracting Essence, 9.7 parts of baeckea frutescen essential oil, 6.8 parts of Rosa Damascana, 10 parts of beeswax, 15 parts of saualane, 6.5 parts of glycerine, aliphatic acid
2.3 parts of polyoxyethylene ester, 1.6 parts of cocoyl glucoside, 1.4 parts of isopropyl hexadecanoate, 2 parts of Sweet Almond Oil, medium chain triglyceride three
2.8 parts of acid esters, 0.2 part of isomery dodecane, 0.8 part of isopropyl myristate, 0.7 part of lauryl alcohol, 0.3 part of methyl oleate are pungent
0.1 part of glycerol decanoate, 0.25 part of eugenol, 0.1 part of Phenoxyethanol, 0.4 part of palmityl alcohol.
Its preparation method of the natural plant essence liquid is same as Example 1.
Embodiment 4
Baeckea frutescen extracts the preparation method of concentrated essence liquid and essential oil, including procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, then
It is put into hydrogen peroxide and is cleaned and sterilized again, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, is dried to moisture content below 5%, then will drying
Branch crush, the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and carries out enzyme 4.5~6.5
Solution, it is incubated 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the appearance of sealing is put into together
In device, heating water bath, the temperature of heating is 40 DEG C, after being incubated 8 hours, is being heated up to 65 DEG C simultaneously, stirring is peeled off 20 minutes；Its
In, the time of heating water bath and mode further refine, the active ingredient of baeckea frutescen powder can be caused it is further proposed that, that is, heat
Temperature is 35 degree and waited 2 hours, and 40 DEG C were then risen in 2 minutes, after being incubated 7 hours, in 5 minutes, is heated up to 60 DEG C
Kept for 5 minutes, 65 DEG C were then heated in 2 minutes and is kept for 10 minutes, one kind is kept stirring within this 20 minutes time.
(6) solution after being peeled off with the filter membrane of 500 mesh to stirring filters, after slag-liquid separation, the use of filter residue again
Alcohol solution dipping, filtering, the filtrate being filtrated to get twice merge；
(7) filtrate is put into container, and for heating water bath to 50-60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen
Essential oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, will remove baeckea frutescen essence
Filtrate pressurization after oil, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate high pressure aperture is saturating
Cross the trapped fluid of liquid and high pressure aperture；
(10) by high pressure aperture permeate, permeate and adsorb through silica gel column chromatography vacuum state, obtain eluent, then will elution
Liquid merges with the trapped fluid of high pressure aperture, obtains extract solution；Wherein silica gel is pH value 6.9, moisture 2.5%, specific surface area 350
Square metre every gram；Before by this technique, high pressure aperture permeate is heated to 78 degrees Celsius,
(11) extract solution is concentrated, amalgamation liquid concentration extracts concentrated essence liquid until baeckea frutescen.
(12) green-tea extract, the Pueraria lobota of 0.075 parts by weight of 0.035 parts by weight are added in baeckea frutescen extracts concentrated essence liquid
The propane diols of root extract and 0.0015 parts by weight, stir and can obtain final baeckea frutescen extraction concentrated essence liquid.4-1's
In embodiment, we are also added into the propane diols of 0.0015 parts by weight so that the homogeneity of product is very good.
After this method crushes baeckea frutescen branch, first digested, then extract essential oil again, finally obtain the liquid that skims the cream off milk,
Fully the active principle in baeckea frutescen can be extracted, add water-soluble collagen wherein as eye mask substrate liquid, it is viscous
Denseness control is 2.3 × 10-3Pa·s。
Embodiment 5
Baeckea frutescen extracts the preparation method of concentrated essence liquid and essential oil, including procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, then
It is put into hydrogen peroxide and is cleaned and sterilized again, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, is dried to moisture content below 5%, then will drying
Branch crush, the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and carries out enzyme 4.5~6.5
Solution, it is incubated 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the appearance of sealing is put into together
In device, heating water bath, the temperature of heating is 35-40 DEG C, after being incubated 6-8 hours, is being heated up to 60-65 DEG C simultaneously, stirring is peeled off
20 minutes；
(6) solution after being peeled off with the filter membrane of 500 mesh to stirring filters, after slag-liquid separation, the use of filter residue again
Alcohol solution dipping, filtering, the filtrate being filtrated to get twice merge；
(7) filtrate is put into container, and for heating water bath to 50-60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen
Essential oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, will remove baeckea frutescen essence
Filtrate pressurization after oil, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate high pressure aperture is saturating
Cross the trapped fluid of liquid and high pressure aperture；
(10) by high pressure aperture permeate, permeate and adsorb through silica gel column chromatography vacuum state, obtain eluent, then will elution
Liquid merges with the trapped fluid of high pressure aperture, obtains extract solution；Wherein, silica gel is pH value 6.5, moisture 2%, specific surface area 320
Square metre every gram；Before by this technique, high pressure aperture permeate is heated to 70 degrees Celsius, adds the green of 0.02 parts by weight
The kudzu root extract of 0.075 parts by weight of tea extraction,
(11) extract solution is concentrated, amalgamation liquid concentration extracts concentrated essence liquid until baeckea frutescen.
After this method crushes baeckea frutescen branch, first digested, then extract essential oil again, finally obtain the liquid that skims the cream off milk,
Fully the active principle in baeckea frutescen can be extracted.
(12) green-tea extract, the root of kudzu vine of 0.06 parts by weight of 0.02 parts by weight are added in baeckea frutescen extracts concentrated essence liquid
The propane diols of extract and 0.001 parts by weight, stir and can obtain final baeckea frutescen extraction concentrated essence liquid.
Embodiment 6
Baeckea frutescen extracts the preparation method of concentrated essence liquid and essential oil, including procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, then
It is put into hydrogen peroxide and is cleaned and sterilized again, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, is dried to moisture content below 5%, then will drying
Branch crush, the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and digested, protected 6.5
Warm 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the appearance of sealing is put into together
In device, heating water bath, the temperature of heating is 35 DEG C, after being incubated 6 hours, is being heated up to 60 DEG C simultaneously, stirring is peeled off 20 minutes；Its
In, the time of heating water bath and mode further refine, the active ingredient of baeckea frutescen powder can be caused it is further proposed that, that is, heat
Temperature is 35 degree and waited 1 hour, and 40 DEG C were then risen in 1 minute, after being incubated 4 hours, in 5 minutes, is heated up to 60 DEG C
Kept for 5 minutes, 65 DEG C were then heated in 1 minute and is kept for 10 minutes, one kind is kept stirring within this 20 minutes time.
(6) solution after being peeled off with the filter membrane of 500 mesh to stirring filters, after slag-liquid separation, the use of filter residue again
Alcohol solution dipping, filtering, the filtrate being filtrated to get twice merge；
(7) filtrate is put into container, and for heating water bath to 60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen essence
Oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, will remove baeckea frutescen essence
Filtrate pressurization after oil, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate high pressure aperture is saturating
Cross the trapped fluid of liquid and high pressure aperture；
(10) by high pressure aperture permeate, permeate and adsorb through silica gel column chromatography vacuum state, obtain eluent, then will elution
Liquid merges with the trapped fluid of high pressure aperture, obtains extract solution；
(11) extract solution is concentrated, amalgamation liquid concentration extracts concentrated essence liquid until baeckea frutescen.
After this method crushes baeckea frutescen branch, first digested, then extract essential oil again, finally obtain the liquid that skims the cream off milk,
Fully the active principle in baeckea frutescen can be extracted, add water-soluble collagen wherein as eye mask substrate liquid, it is viscous
Denseness control is 3.4 × 10-3Pa·s
Embodiment 7
Baeckea frutescen extracts the preparation method of concentrated essence liquid and essential oil, including procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, then
It is put into hydrogen peroxide and is cleaned and sterilized again, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, is dried to moisture content below 5%, then will drying
Branch crush, the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and digested, protected 4.5
Warm 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the appearance of sealing is put into together
In device, heating water bath, the temperature of heating is 35 DEG C, after being incubated 6 hours, is being heated up to 60 DEG C simultaneously, stirring is peeled off 20 minutes；Its
In, the time of heating water bath and mode further refine, the active ingredient of baeckea frutescen powder can be caused it is further proposed that, that is, heat
Temperature is 35 degree and waited 1 hour, and 40 DEG C were then risen in 1 minute, after being incubated 4 hours, in 5 minutes, is heated up to 60 DEG C
Kept for 5 minutes, 65 DEG C were then heated in 1 minute and is kept for 10 minutes, one kind is kept stirring within this 20 minutes time.
(6) solution after being peeled off with the filter membrane of 500 mesh to stirring filters, after slag-liquid separation, the use of filter residue again
Alcohol solution dipping, filtering, the filtrate being filtrated to get twice merge；
(7) filtrate is put into container, and for heating water bath to 60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen essence
Oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, will remove baeckea frutescen essence
Filtrate pressurization after oil, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate high pressure aperture is saturating
Cross the trapped fluid of liquid and high pressure aperture；
(10) by high pressure aperture permeate, permeate and adsorb through silica gel column chromatography vacuum state, obtain eluent, then will elution
Liquid merges with the trapped fluid of high pressure aperture, obtains extract solution；
(11) extract solution is concentrated, amalgamation liquid concentration extracts concentrated essence liquid until baeckea frutescen.
After this method crushes baeckea frutescen branch, first digested, then extract essential oil again, finally obtain the liquid that skims the cream off milk,
Fully the active principle in baeckea frutescen can be extracted.
Embodiment 8
A kind of natural plant essence liquid, by following material by weight：10 parts of deionized water, baeckea frutescen extraction are dense
16.7 parts of contracting Essence, 8 parts of baeckea frutescen essential oil, 18 parts of Rosa Damascana, 6 parts of beeswax, 3 parts of saualane, 8.8 parts of glycerine, fatty acid polyglycol
4 parts of oxygen vinyl acetate, 3.2 parts of cocoyl glucoside, 1.6 parts of isopropyl hexadecanoate, 2.2 parts of Sweet Almond Oil, the acid of medium chain triglyceride three
1.5 parts of ester, 0.5 part of isomery dodecane, 0.6 part of isopropyl myristate, 1 part of lauryl alcohol, 0.2 part of methyl oleate, pungent capric acid
0.2 part of glyceride, 0.15 part of eugenol, -0.4 part of Phenoxyethanol, 0.1 part of palmityl alcohol.
Its preparation method of the natural plant essence liquid, comprises the following steps：
(1) part deionization is taken, Rosa Damascana, beeswax, saualane, cocoyl glucoside, myristic acid are taken according to formula
Isopropyl ester, lauryl alcohol, eugenol, Phenoxyethanol, palmityl alcohol are scattered in deionized water, are thoroughly mixed to have obtained basis
Mixed liquor；
(2) by polyoxyethylene carboxylate, isomery dodecane, isopropyl hexadecanoate, median chain triglyceride oil, oleic acid first
After ester weighs according to formula, it is added in above-mentioned mixed liquor, and carries out heating water bath；
(3) baeckea frutescen essential oil, Sweet Almond Oil, be mixed to get mixed oil liquid；
(5) glycerine, Glycerin, mixed triester with caprylic acid capric acid and remaining deionized water mixing, and carry out heating water bath obtain glycerine mixing it is molten
Liquid；
(6) mixed oil liquid is added drop-wise in glycerine mixed solution, and is stirred, and after stirring 10~30 minutes, is sequentially added
Basic mixed liquor and baeckea frutescen extraction concentrated essence liquid stirs, and produces natural plant essence liquid.
Effect detection
Illustrate the effect of product of the present invention by normal individual trial experiment：From the product obtained by embodiment.
Subjects select：Each half of men and women, 29-67 year every ten years old be an age bracket, be divided into four age brackets, Mei Genian
Each men and women of age section one, health, no skin disease and allergies.
Experiment number：200 people, every one group of 25 people, approached and sex identical crowd for age bracket.
Evaluation index：Canthus, under-eye skin elasticity, hydrauture, transdermal dehydration, wrinkle, pore, skin smoothness.
Test zone：Face, including canthus, now, cheek region.
Test period：Using preceding and using after 19 days.
Skin elasticity is tested：Skin elasticity is also to judge one of important symbol of skin aging, and test position is selected in eye.
Because eye part skin is most thin, without sebum secretion, and eye motion is frequent, more facial other easy agings in position, therefore tests
Now.Because canthus also easily produces wrinkle, canthus is also main detection position.Using MPA580 elasticity testers, at canthus
With a constant negative pressure is applied at under-eye skin, by test skin reply deformation size investigate use cosmetics after skin elasticity
Change, evaluate the senile-resistant efficacies of cosmetics.
The measure index of elasticity is R2, R2=(e (a)-e (a+b)/e (a)：When i.e. without negative pressure the springback capacity of skin and have it is negative
The ratio between maximum tension amount during pressure, ratio illustrate that skin elasticity is better closer to 1.Visible, the skin by front and rear test comparison
Elasticity all has significantly improvement.
The skin elasticity of table 1 tests table
| Test object numbering group | Use preceding elasticity measurement index | Use measure index elastic after 14 days |
| 1 | 0.742 | 0.923 |
| 2 | 0.859 | 0.923 |
| 3 | 0.742 | 0.862 |
| 4 | 0.713 | 0.982 |
| 5 | 0.717 | 0.778 |
| 6 | 0.839 | 0.978 |
| 7 | 0.617 | 0.729 |
| 8 | 0.824 | 0.842 |
Moisture measurement：By can not only be directly acquainted with epiderm skin cuticula moisture content to the measure of moisture of skin
Situation, the degree of skin aging can also be reflected indirectly.Moisture measurement is selected in the trigonum of decree line, investigates pressure object and uses
The change of hydrauture before and after product of the present invention, evaluate cosmetics anti-aging the effect of.It is that skin is relatively dried that hydrauture, which is less than 50,
50-60 is drying, abundant for moisture more than 60.Visible by front and rear test comparison, skin is aqueous all to have significantly improvement,
Major part can reach the sufficient degree of moisture.
The skin elasticity of table 2 tests table
Wrinkle ready visual contrast：The whole cheek chosen now to canthus is analyzed area, investigates experimenter and uses the present invention
The visual sense organ of wrinkle before and after product, evaluate the senile-resistant efficacy of cosmetics.Elimination by estimating visible wrinkle is effective.
The wrinkle of skin of table 3 estimates table
| Test object numbering group | Whether obvious eliminated using wrinkle after 14 days |
| 1 | Substantially |
| 2 | Clearly |
| 3 | It is more apparent |
| 4 | It is more apparent |
| 5 | Substantially |
| 6 | Unobvious |
| 7 | It is more apparent |
| 8 | It is more apparent |
Skin smoothness：By determining the change using regular period skin smoothness after product of the present invention, and use
Front and rear facial smoothness contrast, senile-resistant efficacy that is directly perceived, quantitatively evaluating cosmetics.Smoothness evaluation is by calculating epidermis
Peak dot/valley point realize that peak dot/valley point ratio is more smooth closer to 1 explanation skin.Visible, the skin by front and rear test comparison
Skin smoothness, which all has, significantly to be improved.
The skin smoothness of table 4 tests table
By generality normal individual trial, the effect for the eye mask that the experiment explanation present invention passes through：Selected from 25-65 year crowd
Each 150 of the masculinity and femininity of health, 300 people altogether, the experiment product of product of the present invention is generally sent, by probation
The feedback capture of person is as follows：
As can be seen here, product of the invention is tried out and experimentally achieves extraordinary effect on a large scale in men and women, to face
The total effective rate of skin reaches 96.5%.
Claims (6)
1. a kind of its preparation method of natural plant essence liquid, it is characterised in that preparation method comprises the following steps：
(1) part deionization (amounts of most half, preferably shorter than half) is taken, Rosa Damascana, beeswax, spiny dogfish are taken according to formula
Alkane, cocoyl glucoside, isopropyl myristate, lauryl alcohol, eugenol, Phenoxyethanol, palmityl alcohol are scattered in deionized water
In, it is thoroughly mixed to have obtained basic mixed liquor；
(2) polyoxyethylene carboxylate, isomery dodecane, isopropyl hexadecanoate, median chain triglyceride oil, methyl oleate are pressed
After being weighed according to formula, it is added in above-mentioned mixed liquor, and carries out heating water bath；
(3) baeckea frutescen essential oil, Sweet Almond Oil, be mixed to get mixed oil liquid；
(5) glycerine, Glycerin, mixed triester with caprylic acid capric acid and the mixing of remaining deionized water, and carry out heating water bath and obtain glycerine mixed solution；
(6) mixed oil liquid is added drop-wise in glycerine mixed solution, and is stirred, and after stirring 10~30 minutes, sequentially adds basis
Mixed liquor and baeckea frutescen extraction concentrated essence liquid stir, and produce natural plant essence liquid；
Wherein, 10 parts of deionized water, baeckea frutescen extraction concentrated essence liquid 15-19 parts, baeckea frutescen essential oil 6-9.7 parts, Rosa Damascana 2-18
Part, beeswax 2-10 parts, saualane 3-15 parts, glycerine 6.5-8.8 parts, polyoxyethylene carboxylate 2.3-4.3 parts, cocoyl glucose
Glycosides 1.6-3.2 parts, isopropyl hexadecanoate 1.4-2.1 parts, Sweet Almond Oil 1.3-2.2 parts, median chain triglyceride oil 1.5-2.8
Part, isomery dodecane 0.2-0.5 parts, isopropyl myristate 0.6-1.4 parts, lauryl alcohol 0.7-1.3 parts, methyl oleate 0.1-
0.3 part, Glycerin, mixed triester with caprylic acid capric acid 0.1-0.3 parts, eugenol 0.15-0.25 parts, Phenoxyethanol 0.1-0.4 parts, palmityl alcohol 0.1-0.4
Part.
2. the preparation method of natural plant essence liquid as claimed in claim 1, it is characterised in that wherein described baeckea frutescen extraction concentration
The preparation method of Essence includes procedure below：
(1) the debris soil on baeckea frutescen branch is cleaned out, retains leaf, and cleaned up with clear water, dried, be then placed in
Cleaned and sterilized again in hydrogen peroxide, the mass concentration of hydrogen peroxide is 3%；
(2) the baeckea frutescen branch after sterilization is taken out after draining away the water, moisture content is dried to below 5%, then by the tree of drying
Branch crushes, and the grain diameter after crushing is not more than 1mm；
(3) the baeckea frutescen particle after crushing, to 300 mesh, obtains ultra micro baeckea frutescen powder using ultramicro grinding；
(4) water is added, the quality of water is ultra micro baeckea frutescen powder times, and regulation pH adds cellulase and digested, protected 4.5~6.5
Warm 26-31 DEG C；
(5) according to every 100kg ultra micros baeckea frutescen powder, with the ethanol solution 500kg that purity is 95%, the container of sealing is put into together
Interior, heating water bath, the temperature of heating is 35-40 DEG C, after being incubated 6-8 hours, is being heated up to 60-65 DEG C simultaneously, stirring peels off 20
Minute；
(6) solution after being peeled off with the filter membranes of 500 mesh to stirring filters, after slag-liquid separation, filter residue again use ethanol
Solution soaks, and filtering, the filtrate being filtrated to get twice merges；
(7) filtrate is put into container, and for heating water bath to 50-60 DEG C, baeckea frutescen essential oil is pooled to the surface of liquid, collects baeckea frutescen essence
Oil；
(8) remaining filtrate uses Ultra filtration membrane processing method, sets ultrafiltration granularity as 0.01 μm, after baeckea frutescen essential oil is removed
Filtrate pressurization, tiny residue is retained by the 0.01 μm of ultrafiltration of low pressure macropore and obtains low pressure macropore permeate；
(9) by low pressure macropore permeate, the ultrafiltration through membranes through 0.00l μm of high pressure aperture retain again, separate to obtain high pressure aperture permeate
With the trapped fluid of high pressure aperture；
(10) extract solution is concentrated, amalgamation liquid is concentrated to give baeckea frutescen extraction concentrated essence liquid.
3. the preparation method of natural plant essence liquid as claimed in claim 2, it is characterised in that
Between step (9) and step (10), preferably it can also increase following steps：By high pressure aperture permeate, through silica gel
The infiltration absorption of column chromatography vacuum state, obtains eluent, then merges eluent with the trapped fluid of high pressure aperture, extracted
Liquid.
4. the preparation method of natural plant essence liquid as described in Claims 2 or 3, it is characterised in that extract concentration essence in baeckea frutescen
The green-tea extract of 0.02-0.035 parts by weight and the kudzu root extract of 0.06-0.075 parts by weight are added in magnificent liquid.
A kind of 5. natural plant essence liquid obtained using any one method in such as claim 1-4.
A kind of 6. method for preparing eye mask substrate liquid using such as claim 5 natural plant essence liquid, it is characterised in that：In elite
The water-soluble collagen of convention amount is added in liquid.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625684A (en) * | 2017-10-11 | 2018-01-26 | 王亚君 | A kind of natural plant essence eye mask substrate liquid and preparation method thereof |
| CN114250178A (en) * | 2021-12-21 | 2022-03-29 | 泰伦特生物工程股份有限公司 | Microbial preparation for removing organic matters on metal surface and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420427A (en) * | 2016-12-05 | 2017-02-22 | 广西天源岗松油有限公司 | Skin-moisturizing lotion containing Baeckea frutescens essential oil and preparation method of skin-moisturizing lotion containing Baeckea frutescens essential oil |
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- 2017-09-15 CN CN201710829594.0A patent/CN107496244A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106420427A (en) * | 2016-12-05 | 2017-02-22 | 广西天源岗松油有限公司 | Skin-moisturizing lotion containing Baeckea frutescens essential oil and preparation method of skin-moisturizing lotion containing Baeckea frutescens essential oil |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625684A (en) * | 2017-10-11 | 2018-01-26 | 王亚君 | A kind of natural plant essence eye mask substrate liquid and preparation method thereof |
| CN114250178A (en) * | 2021-12-21 | 2022-03-29 | 泰伦特生物工程股份有限公司 | Microbial preparation for removing organic matters on metal surface and preparation method thereof |
| CN114250178B (en) * | 2021-12-21 | 2024-01-23 | 泰伦特生物工程股份有限公司 | Microbial preparation for removing organic matters on metal surface and preparation method thereof |
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Application publication date: 20171222 |