CN107441390A - A kind of fat burning and slimming frost and preparation method - Google Patents

A kind of fat burning and slimming frost and preparation method Download PDF

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Publication number
CN107441390A
CN107441390A CN201710456152.6A CN201710456152A CN107441390A CN 107441390 A CN107441390 A CN 107441390A CN 201710456152 A CN201710456152 A CN 201710456152A CN 107441390 A CN107441390 A CN 107441390A
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extract
slimming
fat
frost
fat burning
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申文林
曾思珉
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Guangzhou Zhongsheng Biological Technology Co Ltd
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Guangzhou Zhongsheng Biological Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K2236/30—Extraction of the material
    • A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction

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Abstract

The invention discloses a kind of fat burning and slimming frost and preparation method, including following components and content (parts by weight)：Disappear fat active blend：9.721 60.703, emulsifying agent：8 17.5, grease：15.101 the 37.909th, thickener：0.11 0.54, NMF：13.5 57.5, chelating agent：0.1 0.7, pH nertralizers：0.5 4, essence：0.82 4.08, preservative：0.4 2.25, deionized water：40 80, the fat active blend that disappears includes combination one or more of in peppermint leaf extract, Pelargonium roseum extract, golden yellow camomile extract, kuh-seng root extract, purslane extract, aloe barbadensis Miller leaf extract, the fragrant cocoa berry extract of Brazil, Semen Coicis extract, licorice, Salvia root P.E, radix codonpsis tangshen extract, Ovshinsky marine algae extract, oolong extract, astragatus complanatus extract, Ligusticum wallichii root extract.Addition chelating agent, pH nertralizers, essence, preservative after the completion of emulsifying is added in the mixture of water, NMF and thickener after grease and emulsifying agent are melted to be made.With good fat burning and slimming effect.

Description

A kind of fat burning and slimming frost and preparation method
Technical field
The present invention relates to a kind of creams and preparation method, more particularly to a kind of fat burning and slimming frost and preparation method.
Background technology
The fat-reducing mode that people commonly use at present mainly has following several：The first, chemotherapy is that is, bent using western cloth Bright or orlistat, this method have very big side effect, have forbidden adding in health food and cosmetics at present；The Two kinds, operative treatment, it is to be understood that operation technique simultaneously has compliance, is not addicted to drink, no drug dependence, can undergo surgery risk And the operation is put somebody on a diet, but this kind of method easily produce the complication such as leakage of mega-esophagus, ring, infection, corrode, ring is slided The problems such as dynamic；The third, is treated using biological agent, i.e., is treated by recombinating Leptin (leptin), but at present due to Leptin biochemical action is more complicated, and the understanding to its mechanism of action is still not comprehensive enough, it is understood that there may be side effect；4th kind, To be treated using Traditional chinese medicine medicament, it easily reaches the advantages of having both with nutrition of curing the disease, but because herbal species are more, systematic Study Shortage, extracts active ingredients are difficult, the problems such as a variety of incompatibility be present, cause medicament configuration difficult, after different users' use Effect is unstable.
Gained knowledge according to existing Human Physiology, the fat in human body is mainly carried out in three liver, small intestine, adipose tissue places Synthesis.And the fat in human body can be digested and assimilated by the pancreatic lipase in pancreatic juice, bile, Epithelium of intestinal villus cell. The fat being present in adipose tissue is broadly divided into white adipose tissue and brown adipose tissue.White adipose tissue form is white Color or yellow, a large amount of unilocular adipose cells are formed, and have a big fat drips into the cell, Mitochondria content is few, and cell is rounded or more Side shape, almost spreads over whole body, and subcutaneous fat and interior fat are major storage energy position.Brown adipose tissue form is Brown, there is abundant capillary in tissue, there are many small fat drips into the cell, mitochondria is big and enriches, mainly for generation of heat Amount.White adipose tissue can be converted into cream-coloured adipose tissue under certain condition, and cream-coloured adipose tissue has and brown fat The similar function of fat tissue, is consumed easily by the mode of heat production.White adipocyte is promoted to turn to cream-coloured adipocyte Change, advantageously reduce fat, reach the effect of fat-reducing.
But there is no product or method still at present, using promoting white adipocyte to cream-coloured adipocyte transforming side Method, people are helped to reduce fat deposition, to reach health, the effect of safe fat-reducing.
The content of the invention
For above-mentioned deficiency, it is an object of the invention to provide a kind of fat that disappears based on combined Chinese herb active blend Weight reducing frost and preparation method, with reference to modern biotechnology science and theory of traditional Chinese medical science, help user accelerate adipose tissue metabolism and point Solution, so as to reach the effect of healthy, safe fat burning and slimming, and combined Chinese herb active blend meets drug matching, is easy to match somebody with somebody Put, safe to use, the fat-reducing, slimming effect after different users' use are stable.
The present invention is that technical scheme is used by reaching above-mentioned purpose：
A kind of fat burning and slimming frost, is made up of the component of following parts by weight：
Disappear fat active blend 9.721‐60.703
Emulsifying agent 8‐17.5
Grease 15.101‐37.909
Thickener 0.11‐0.54
NMF 13.5‐57.5
Chelating agent 0.1‐0.7
PH nertralizers 0.5‐4
Essence 0.82‐4.08
Preservative 0.4‐2.25
Deionized water 40‐80
Wherein, the fat active blend that disappears is peppermint leaf extract, Pelargonium roseum extract, the extraction of golden yellow chamomile Thing, kuh-seng root extract, purslane extract, aloe barbadensis Miller leaf extract, the fragrant cocoa berry extract of Brazil, coix seed extraction Thing, licorice, Salvia root P.E, radix codonpsis tangshen extract, Ovshinsky marine algae extract, oolong extract, astragatus complanatus One or more of combination in extract, Ligusticum wallichii root extract.
As a further improvement on the present invention, the fat active blend that disappears is extracted by supercritical extraction technique to obtain, It is made up of the component of following parts by weight：
Peppermint leaf extract 2‐18
Pelargonium roseum extract 0.1‐0.5
Golden yellow camomile extract 0.001‐0.002
Kuh-seng root extract 1‐4
Purslane extract 0.1‐0.5
Aloe barbadensis Miller leaf extract 1‐4.5
The fragrant cocoa berry extract of Brazil 0.5‐2
Semen Coicis extract 0.00001‐0.00006
Licorice 1‐4.1
Salvia root P.E 1‐6.5
Radix codonpsis tangshen extract 0.5‐2.4
Ovshinsky marine algae extract 0.01‐0.1
Oolong extract 0.01‐0.1
Astragatus complanatus extract 0.5‐3
Ligusticum wallichii root extract 2‐15
Wherein, each extract of fat active blend that disappears is extracted as follows respectively：
(1) raw material of each extract is crushed by pulverizer；
(2) raw material is fitted into extraction kettle, sets extraction temperature as 35~65 DEG C, extracting pressure 8-15Mpa, extraction Time is 0.5~2.5h, CO2Flow is 20-50L/h, is extracted；
(3) after extraction reaches specified time, pressure-reducing valve is adjusted, is decompressed to normal pressure, and collect extract.
Dried peppermint leaf (Mentha Arvensis) extract main component is peppermint oil and menthol；
The Main Ingredients and Appearance of Pelargonium roseum (Pelargonium Graveolens) extract is citronellol, spiceleaf Alcohol, linalool, formic acid vanilla ester, pulegone；
The main component of golden yellow chamomile (CHRYSANTHELLUM INDICUM) extract is cyanidenon, celery Element, luteolin-7-glucoside, apiin member -7- glucosides, ayapanin；
The main component of radix sophorae (SOPHORA ANGUSTIFOLIA) extract is：Vexibinol, Xanthohumol, hardship Join pyridine, trifolirhizin, oxymatrine, N-Oxysophocarpine, matrine, sophocarpine；
The main component of purslane (PORTULACA OLERACEA) extract is：Alpha-linolenic acid；
The main component of Aloe Barbadensis Miller (ALOE BARBADENSIS) extract is：Aloe polysaccharide, barbaloin, Aloe-emodin, aloe Rhein；
The main component of the fragrant cocoa of Brazil (PAULLINIA CUPANA) extract is：Cocoa polyphenol；
The main component of coix seed (the COIX LACRYMA-JOBI MA-YUEN) extract is：1,2- oleic acid -3- is sub- Oleic acid-triglycerides, glycerol trioleate, 1,2- oleic acid -3- palmitic acids-triglycerides；
The main component of radix glycyrrhizae (GLYCYRRHIZA URALENSIS) extract is：Licoflavone class material, tonka-bean Smart class material and enoxolone；
The main component of the red sage root (SALVIA MILTIORRHIZA) extract is：Sodium Danshensu, tanshin polyphenolic acid B, dihydro Tanshinone I, Tanshinone I, Cryptotanshinone, tanshinone IIA；
The main component of radix codonpsis tangshen (CODONOPSIS TANGSHEN) extract is：Lobetyolin, Codonopsis pilosula polysaccharide, Atractylenoide Ⅲ；
The main component of Ovshinsky marine alga (CLADOSIPHON OKAMURANUS) extract is：Flavonoid substances, β- Carrotene, VitAVitE, gamma-Linolenic acid, linoleic acid；
The main component of oolong (CAMELLIA SINENSIS) extract is：Tea Polyphenols, tea polysaccharide；
The main component of astragatus complanatus (ASTRAGALUS COMPLANATUS) extract is：It is glucan, flavones, different Flavones, red sandalwood alkane, isoflavan, soyasaponin, astragaloside；
The main component of Ligusticum wallichii root (LIGUSTICUM CHUANXIONG) extract is：Ligustilide, 3- Ding Fu Lactone, sabinene.
As a further improvement on the present invention, the grease be saualane, isononyl isononanoate, isopropyl myristate, One or more of combination in jojoba seed oil, cetostearyl alcohol, oleic acid, dimethyl silicone polymer, by the group of following parts by weight It is grouped into：
The NMF is combinations one or more of in glycerine, glycerin polyether -26, butanediol, allantoin, propane diols, It is made up of the component of following parts by weight：
Glycerine 5‐25
Glycerin polyether -26 1‐4.5
Butanediol 5‐19
Allantoin 0.5‐1
Propane diols 2‐8
As a further improvement on the present invention, the emulsifying agent is stearine, PEG-100 stearates, spermaceti One or more of combination in stearyl glucoside, is made up of the component of following parts by weight：
Stearine 5‐10
PEG-100 stearates 2‐5
Cetearyl glucoside 1‐2.5
As a further improvement on the present invention, the thickener is hydroxypropyl melon glue or/and hydroxyethyl cellulose, by with The component composition of lower parts by weight：
Hydroxypropyl melon glue 0.1‐0.5
Hydroxyethyl cellulose 0.01‐0.04
As a further improvement on the present invention, the preservative is methyl hydroxybenzoate, Nipasol, Sensiva SC50, chlorine One or more of combination in the sweet ether of benzene, Phenoxyethanol, Bis(hydroxymethyl)imidazolidinyl urea, by the component group of following parts by weight Into：
Methyl hydroxybenzoate 0‐0.5
Nipasol 0‐0.14
Sensiva SC50 0.1‐0.5
Chlorphenesin 0.1‐0.3
Phenoxyethanol 0.1‐0.3
Bis(hydroxymethyl)imidazolidinyl urea 0.1‐0.5
As a further improvement on the present invention, the essence is a kind of in JIANGGENYOU, Cupressus semperviren wood oil, Juniperus communis fruit oil Or several combinations, it is made up of the component of following parts by weight：
JIANGGENYOU 0.3‐1
Cupressus semperviren wood oil 0.5‐3
Juniperus communis fruit oil 0.02‐0.08
As a further improvement on the present invention, the pH nertralizers are triethanolamine, and its content (parts by weight) is 0.5- 4；The chelating agent is EDETATE SODIUM, and its content (parts by weight) is 0.1-0.7；
The fat burning and slimming frost also includes：Anti-oxidant tocopherol acetic acid esters, its content (parts by weight) are 1-2.2；Ooze Saturating agent Laurocapram, its content (parts by weight) is 0.3-2；Heat sensitizer VBE, its content (parts by weight) are 0.001‐0.005；Laureth sodium sulfovinate, its content (parts by weight) are 0.001-0.002.
As a further improvement on the present invention, in addition to opacifier calcium sulfate, its content are 0.5-3.
A kind of preparation method of fat burning and slimming frost, comprises the following steps：
(1) grease is mixed with emulsifying agent at 90-95 DEG C, melt to mixture can good flow, be cooled to 75-80 DEG C It is standby, obtain oil phase A；
(2) NMF, thickener are well mixed with water, be heated to 75-80 DEG C it is standby, obtain mixture B；
(3) at stirring condition, 75-80 DEG C, oil phase A is poured slowly into mixture B, emulsified, thereafter using equal Matter machine carries out homogeneous；
(4) after being cooled to 35-40 degrees Celsius, the fat active blend that disappears, pH nertralizers, chelating agent, essence, anti-is sequentially added Rotten agent；
(5) after being sufficiently stirred, fat burning and slimming frost is obtained.
Wherein, the fat active blend that disappears is peppermint leaf extract, Pelargonium roseum extract, the extraction of golden yellow chamomile Thing, kuh-seng root extract, purslane extract, aloe barbadensis Miller leaf extract, the fragrant cocoa berry extract of Brazil, coix seed extraction Thing, licorice, Salvia root P.E, radix codonpsis tangshen extract, Ovshinsky marine algae extract, oolong extract, astragatus complanatus One or more of combination in extract, Ligusticum wallichii root extract.
As a further improvement on the present invention, the step (2) also comprises the following steps：
(2.1) laureth sodium sulfovinate is added in mixture B, stirred；
Step (4) also comprises the following steps：
(4.1) antioxidant, bleeding agent, heat sensitizer and opacifier are sequentially added.
Beneficial effects of the present invention are：
(1) the convenient administration approach of Chinese medicine is absorbed, through stomach after drug oral based on oral after drug oral through intestines and stomach Intestinal epithelial cell is distributed to each histoorgan into the laggard human body of blood circulation system transhipment and played a role, but extract oral Administration generally requires to take the cycle for more than 1 month, and dose is big, orally after a series of processes such as gastric digestion, effectively It is high that composition reaches small intestine difficulty, causes absorptivity low, it is difficult to see obvious weight loss effect, long-term use be also easy to kidney, Liver causes larger load, or even causes to damage, and the present invention compounding after traditional Chinese medicine extyaction is made the formulation of determination, Using transdermal drag delivery, osmosis is improved by the bleeding agent of the composite such as bleeding agent and peppermint leaf extract, protected Humectant improves skin hydration degree, so as to promote effective component of chinese medicine rapidly and efficiently to pass through epidermis, while ancient Chinese medical classics in application Cave is theoretical, and product is applied on the point of acupuncture point, active ingredient is gone directly application point, substantially increases the absorptivity of Chinese medicine, And dosage is low more than oral administration amount, white adipocyte can be effectively facilitated to cream-coloured adipocyte transforming, advantageously reduced Fat, changing Chinese medicine tradition needs oral situation about can just tell on, and realizes external application Chinese medicine and reaches excellent lowering blood-fat and reducing weight modeling Body effect, can effective more than 10 jin of loss of weight using 14 days；
(2) fat burning and slimming frost is acted on some acupuncture points or privileged site, using medicine to the stimulation at acupuncture point and itself Pharmacological action come reach disappear fat body shaping purpose；Channels and collaterals are the conducting systems that the whole body is contacted in human body communication table, belong to mansion in it Hide, outer network is in detail, and the sensible whole body of delivery qi and blood is everywhere；Point application therapy and intestines and stomach, vein, the area of intramuscular administration route It is not only in that drug delivery route in itself, it is often more important that to be that medicine is absorbed by the defeated cave of channels and collaterals, transmission, what is utilized is same When, meridian point makes stronger reaction to medicine irritation, and medicine is acted on and amplified.Spreading on the medicine of SHENJUE acupoint can effectively excite Three arteries and veins through gas, conduct through subcutaneous fat cells and intestinal fat cell target spot by channels and collaterals, realize lowering blood-fat and reducing weight body shaping Effect；
(3) suppress the expression of adipocyte Leptin mRNA, improve the resistant function of insulin, accelerate the metabolism of adipose tissue With decomposition, promote energy expenditure, so as to reduce leptin level around adipocyte；
(4) effect of serum free fatty acid is reduced, suppresses the absorption of cholesterol and influences cholesterol in the esterified of small intestine, And solubility and cholesterol before it is absorbed necessary emulsion process of the cholesterol in small intestine site is reduced, significantly inhibit cholesterol Absorb；
(5) suppress the uciferase activity genetic transcription synthesis of people's adipocyte secretion factor gene promoter, promote fat Fat coefficient and adipocyte diameter diminish, and reduce serum total cholesterol and triglyceride levels, and by promoting body lipid Transhipment and excretion, regulating lipid metabolism, it is suppressed that fatty synthesis reaches the effect of lowering blood-fat and reducing weight；
(6) clearing heat and expelling damp of the present invention, the strong stomach of invigorating the spleen, may also function as the effect of auxiliary treatment eczema；
(7) women of the present invention uses before menstrual period, also has the effect for substantially slowing down dysmenorrhoea.
Above-mentioned is the general introduction of inventive technique scheme, and below in conjunction with embodiment, the present invention will be further described.
Embodiment
Further to illustrate the present invention to reach the technological means and effect that predetermined purpose is taken, below in conjunction with preferable Embodiment, the embodiment of the present invention is described in detail.
Embodiment 1
The present embodiment provides a kind of fat burning and slimming frost, is made up of the component of following parts by weight：
A kind of preparation method of fat burning and slimming frost, comprises the following steps：
(1) grease is mixed with emulsifying agent at 90-95 DEG C, melt to mixture can good flow, be cooled to 75-80 DEG C It is standby, obtain oil phase A；
(2) NMF, thickener are well mixed with water, be heated to 75-80 DEG C it is standby, obtain mixture B；
(2.1) laureth sodium sulfovinate is added in mixture B, stirred；
(3) at stirring condition, 75-80 DEG C, oil phase A is poured slowly into mixture B, emulsified, thereafter using equal Matter machine carries out homogeneous；
(4) after being cooled to 35-40 degrees Celsius, the fat active blend that disappears, pH nertralizers, chelating agent, essence, anti-is sequentially added Rotten agent；
(4.1) antioxidant, bleeding agent, heat sensitizer and opacifier are sequentially added；
(5) after being sufficiently stirred, fat burning and slimming frost is obtained.
Embodiment 2
The present embodiment provides a kind of fat burning and slimming frost, is made up of the component of following parts by weight：
A kind of preparation method of fat burning and slimming frost, comprises the following steps：
(1) grease is mixed with emulsifying agent at 90-95 DEG C, melt to mixture can good flow, be cooled to 75-80 DEG C It is standby, obtain oil phase A；
(2) NMF, thickener are well mixed with water, be heated to 75-80 DEG C it is standby, obtain mixture B；
(2.1) laureth sodium sulfovinate is added in mixture B, stirred；
(3) at stirring condition, 75-80 DEG C, oil phase A is poured slowly into mixture B, emulsified, thereafter using equal Matter machine carries out homogeneous；
(4) after being cooled to 35-40 degrees Celsius, the fat active blend that disappears, pH nertralizers, chelating agent, essence, anti-is sequentially added Rotten agent；
(4.1) antioxidant, bleeding agent, heat sensitizer and opacifier are sequentially added；
After being sufficiently stirred, fat burning and slimming frost is obtained.
Embodiment 3
The present embodiment provides a kind of fat burning and slimming frost, is made up of the component of following parts by weight：
A kind of preparation method of fat burning and slimming frost, comprises the following steps：
(1) grease is mixed with emulsifying agent at 90-95 DEG C, melt to mixture can good flow, be cooled to 75-80 DEG C It is standby, obtain oil phase A；
(2) NMF, thickener are well mixed with water, be heated to 75-80 DEG C it is standby, obtain mixture B；
(2.1) laureth sodium sulfovinate is added in mixture B, stirred；
(3) at stirring condition, 75-80 DEG C, oil phase A is poured slowly into mixture B, emulsified, thereafter using equal Matter machine carries out homogeneous；
(4) after being cooled to 35-40 degrees Celsius, the fat active blend that disappears, pH nertralizers, chelating agent, essence, anti-is sequentially added Rotten agent；
(4.1) antioxidant, bleeding agent, heat sensitizer and opacifier are sequentially added；
After being sufficiently stirred, fat burning and slimming frost is obtained.
Effect example 1
The gained fat burning and slimming of embodiment 3 frost is subjected to loss of weight performance test, method of testing is：Take under appropriate be applied to entirely Belly, massage take soya bean size to be put in SHENQUE acupoint after absorbing, sooner or later each to smear once.Test is front and rear to carry out body weight and abdominal circumference Detection, 50 people are chosen, age 20-60 year, each 25 people of men and women, by operation instruction, using continuing for 4 week, it is as follows to obtain result： Each one 5-10 kilograms of weight loss, waistline reduce 3-5 centimetres.
Case 1：X man, 23 years old, be 95.5 kilograms using preceding measured body weight, and after 3 weeks, measured body weight is 84.65 public Jin.
Case 2：X man, 36 years old, be 82.65 kilograms using preceding measured body weight, after 14 days, measured body weight 76.5 Kilogram.
Case 3：X man, 47 years old, be 106CM using preceding measurement of girth, after 30 days, measurement of girth 89CM.
Case 4：Mrs X, 51 years old, be 59 kilograms using preceding measured body weight, and after 18 days, measured body weight is 53 kilograms.
It can be seen that the present invention has good fat burning and slimming effect.
The emphasis of the present invention is essentially consisted in, and Chinese medicine is made to certain formulation, acted on some acupuncture points or privileged site, The purpose for the fat body shaping that disappears is reached to the stimulation at acupuncture point and pharmacological action itself using medicine, conducts the subcutaneous fat that goes directly by channels and collaterals Fat cell and intestinal fat cell target spot, play the fluorescein enzyme activity of Drug inhibition people's adipocyte secretion factor gene promoter Property genetic transcription synthesis, promote fat coefficient and adipocyte diameter to diminish, reduce serum total cholesterol and triglyceride levels, And by promoting the transhipment and excretion of body lipid, regulating lipid metabolism, it is suppressed that fatty synthesis reaches lowering blood-fat and reducing weight The effect of body shaping.
The above described is only a preferred embodiment of the present invention, be not intended to limit the scope of the present invention, Therefore identical with the above embodiment of the present invention or approximate technical characteristic is used, within protection scope of the present invention.

Claims (10)

1. a kind of fat burning and slimming frost, it is characterised in that be made up of the component of following parts by weight：
Disappear fat active blend 9.721-60.703 Emulsifying agent 8-17.5 Grease 15.101-37.909 Thickener 0.11-0.54 NMF 13.5-57.5 Chelating agent 0.1-0.7 PH nertralizers 0.5-4 Essence 0.82-4.08 Preservative 0.4-2.24 Deionized water 40-80
Wherein, it is described disappear fat active blend for peppermint leaf extract, Pelargonium roseum extract, golden yellow camomile extract, Kuh-seng root extract, purslane extract, aloe barbadensis Miller leaf extract, the fragrant cocoa berry extract of Brazil, Semen Coicis extract, Licorice, Salvia root P.E, radix codonpsis tangshen extract, Ovshinsky marine algae extract, oolong extract, astragatus complanatus extraction One or more of combination in thing, Ligusticum wallichii root extract.
2. fat burning and slimming frost as claimed in claim 1, it is characterised in that the fat active blend that disappears is by following parts by weight Component, by supercritical extraction technique extract and：
。
3. fat burning and slimming frost as claimed in claim 1, it is characterised in that the grease is saualane, isononyl isononanoate, meat One or more of combinations, described in isopropyl myristate, jojoba seed oil, cetostearyl alcohol, oleic acid, dimethyl silicone polymer NMF includes combination one or more of in glycerine, glycerin polyether -26, butanediol, allantoin, propane diols.
4. fat burning and slimming frost as claimed in claim 1, it is characterised in that the emulsifying agent is stearine, PEG-100 One or more of combination in stearate, cetearyl glucoside；The thickener includes hydroxypropyl melon glue or/and hydroxyl Ethyl cellulose.
5. fat burning and slimming frost as claimed in claim 1, it is characterised in that the preservative is methyl hydroxybenzoate, Nipasol, second One or more of combination in base hexyl glycerine, Chlorphenesin, Phenoxyethanol, Bis(hydroxymethyl)imidazolidinyl urea.
6. fat burning and slimming frost as claimed in claim 1, it is characterised in that the essence is JIANGGENYOU, Cupressus semperviren wood oil, Europe One or more of combination in juniper berries oil.
7. fat burning and slimming frost as claimed in claim 1, it is characterised in that the pH nertralizers are triethanolamine, its content (weight Measure number) it is 0.5-4；The chelating agent is EDETATE SODIUM, and its content (parts by weight) is 0.1-0.7；
The fat burning and slimming frost also includes：Anti-oxidant tocopherol acetic acid esters, its content (parts by weight) are 1-2.2；Bleeding agent Laurocapram, its content (parts by weight) are 0.3-2；Heat sensitizer VBE, its content (parts by weight) are 0.001-0.005；Laureth sodium sulfovinate, its content (parts by weight) are 0.001-0.002.
8. fat burning and slimming frost as claimed in claim 1, it is characterised in that also including opacifier calcium sulfate, its content is 0.5- 3。
9. a kind of preparation method of the frost of the fat burning and slimming as described in claim any one of 1-8, it is characterised in that including following step Suddenly：
(1) grease is mixed with emulsifying agent at 90-95 DEG C, melt to mixture can good flow, be cooled to 75-80 DEG C it is standby With obtaining oil phase A；
(2) NMF, thickener are well mixed with water, be heated to 75-80 DEG C it is standby, obtain mixture B；
(3) at stirring condition, 75-80 DEG C, oil phase A is poured slowly into mixture B, emulsified, thereafter using homogenizer Carry out homogeneous；
(4) after being cooled to 35-40 degrees Celsius, the fat active blend that disappears, pH nertralizers, chelating agent, essence, anti-corrosion are sequentially added Agent；
(5) after being sufficiently stirred, fat burning and slimming frost is obtained；
Wherein, it is described disappear fat active blend for peppermint leaf extract, Pelargonium roseum extract, golden yellow camomile extract, Kuh-seng root extract, purslane extract, aloe barbadensis Miller leaf extract, the fragrant cocoa berry extract of Brazil, Semen Coicis extract, Licorice, Salvia root P.E, radix codonpsis tangshen extract, Ovshinsky marine algae extract, oolong extract, astragatus complanatus extraction One or more of combination in thing, Ligusticum wallichii root extract.
10. the preparation method of fat burning and slimming frost as claimed in claim 9, it is characterised in that the step (2) also includes following step Suddenly：
(2.1) laureth sodium sulfovinate is added in mixture B, stirred；
Step (4) also comprises the following steps：
(4.1) antioxidant, bleeding agent, heat sensitizer and opacifier are sequentially added.
CN201710456152.6A 2017-06-16 2017-06-16 A kind of fat burning and slimming frost and preparation method Pending CN107441390A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653693A (en) * 2018-06-15 2018-10-16 华南理工大学 A kind of slim fat rush digestion micro emulsion and preparation method thereof that disappears
CN109481320A (en) * 2018-12-12 2019-03-19 广州睿森生物科技有限公司 A kind of fat reducing weight reducing microemulsion and preparation method thereof
CN110302119A (en) * 2019-08-15 2019-10-08 杭州千岛湖蓝色天使实业有限公司 A kind of slimming moisturizing essence and preparation method thereof
CN110327278A (en) * 2019-08-15 2019-10-15 杭州千岛湖蓝色天使实业有限公司 A kind of slimming moisturizing essence cream and preparation method thereof
CN110721133A (en) * 2019-11-29 2020-01-24 海南女人春天美容有限公司 Light firming nourishing cream and preparation method thereof
CN111529446A (en) * 2020-05-28 2020-08-14 广州娇美生物科技有限公司 Massage cream for tightening skin and preparation method thereof
CN114983887A (en) * 2022-05-30 2022-09-02 广州麦嘉昕生物科技有限公司 Beautiful and light herbal liquid
CN115364021A (en) * 2021-11-23 2022-11-22 广州市百爱神生物科技有限公司 Cream containing supercritical plant extract and preparation method thereof
CN115737463A (en) * 2022-09-30 2023-03-07 泉后(广州)生物科技研究院有限公司 Fat-reducing and body-shaping cream as well as preparation method and application thereof

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108653693A (en) * 2018-06-15 2018-10-16 华南理工大学 A kind of slim fat rush digestion micro emulsion and preparation method thereof that disappears
CN109481320A (en) * 2018-12-12 2019-03-19 广州睿森生物科技有限公司 A kind of fat reducing weight reducing microemulsion and preparation method thereof
CN110302119A (en) * 2019-08-15 2019-10-08 杭州千岛湖蓝色天使实业有限公司 A kind of slimming moisturizing essence and preparation method thereof
CN110327278A (en) * 2019-08-15 2019-10-15 杭州千岛湖蓝色天使实业有限公司 A kind of slimming moisturizing essence cream and preparation method thereof
CN110721133A (en) * 2019-11-29 2020-01-24 海南女人春天美容有限公司 Light firming nourishing cream and preparation method thereof
CN111529446A (en) * 2020-05-28 2020-08-14 广州娇美生物科技有限公司 Massage cream for tightening skin and preparation method thereof
CN115364021A (en) * 2021-11-23 2022-11-22 广州市百爱神生物科技有限公司 Cream containing supercritical plant extract and preparation method thereof
CN115364021B (en) * 2021-11-23 2024-02-13 广州市百爱神生物科技有限公司 A cream containing supercritical plant extract and its preparation method
CN114983887A (en) * 2022-05-30 2022-09-02 广州麦嘉昕生物科技有限公司 Beautiful and light herbal liquid
CN115737463A (en) * 2022-09-30 2023-03-07 泉后(广州)生物科技研究院有限公司 Fat-reducing and body-shaping cream as well as preparation method and application thereof
CN115737463B (en) * 2022-09-30 2024-05-14 泉后(广州)生物科技研究院有限公司 Fat-reducing shaping cream and preparation method and application thereof

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Application publication date: 20171208