CN104147147A - Traditional Chinese medicinal composition for treating skin diseases and preparation method thereof - Google Patents

Traditional Chinese medicinal composition for treating skin diseases and preparation method thereof Download PDF

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CN104147147A
CN104147147A CN201310697974.5A CN201310697974A CN104147147A CN 104147147 A CN104147147 A CN 104147147A CN 201310697974 A CN201310697974 A CN 201310697974A CN 104147147 A CN104147147 A CN 104147147A
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CN104147147B (en
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刘全喜
刘巧霞
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Liu Qiaoxia
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HENAN MINGXUAN FOOD TECHNOLOGY Co Ltd
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Abstract

The invention discloses a traditional Chinese medicinal composition for treating skin diseases and a preparation method thereof, and belongs to the technical field of traditional Chinese medicinal composition. The traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 80-120 parts of polygonum multiflorum, 40-60 parts of fructus psoraleae, 5-10 parts of medical pipefish, 15-20 parts of hippocampus, 40-60 parts of semen cuscutae, 20-40 parts of divaricate saposhnikovia root, 20-40 parts of eucommia ulmoides, 1-3 parts of centipede, 20-40 parts of radix angelicae pubescentis, 30-50 parts of zaocys dhumnade, 30-50 parts of salviae miltiorrhizae, 20-40 parts of bombyx batryticatus, 50-70 parts of esliptae herba, 20-40 parts of radix angelicae, 50-70 parts of astragalus membranaceus and 40-60 parts of manyprickle acanthopanax root. The traditional Chinese medicinal composition has the effects of nourishing yin and tonifying kidney, dispelling wind and activating blood and the like, is mainly used for treating leukoderma, and also can be used for treating tinea versicolor, pityriasis rosea, anaphylactoid purpura, seborrheic dermatitis and ichthyosis.

Description

A kind of dermopathic Chinese medicine composition and preparation method of being used for the treatment of
Technical field
The present invention is specifically related to a kind ofly be used for the treatment of dermopathic Chinese medicine composition, and the preparation method of this Chinese medicine composition, belongs to Chinese medicine technical field.
Background technology
Medically, dermatosis is one of the checking commonly encountered diseases that affects people ' s health, frequently-occurring disease, as leprosy, scabies, mycosis, bacterial skin infections etc.Dermatosis is that skin (comprising hair and first) is subject to after the impact of internal and external factor, and its form, 26S Proteasome Structure and Function all change, and produces pathological process, and produces accordingly various clinical priority performances.How low weight dermopathic sickness rate is very high,, often not unhealthful, even can threat to life but minority is heavier.
Vitiligo is a kind of common posteriority limit office property or general the de-disease of losing of property skin pigment.Because the melanocyte defunctionalization of skin causes, each position of whole body can occur, and is common in and refers to the back of the body, wrist, forearm, face, neck etc.Clinical manifestation is sex no significant difference, and each age group all can be fallen ill, but sends out well with teenager.Skin lesion is depigmentation speckle, is often milky, also can be lightpink, and smooth surface is without erythra, and white macula boundary is clear, and edge pigment compared with normal skin increases, and in white macula, hair is normal or bleach.Pathological changes is apt to occur in and is subject to solar radiation and frictionally damage position, and how symmetrical disease damage is.White macula also often distributes by nerve segment and is banded arrangement.
Tinea versicolor is that its skin lesion is characterized as point-like or strip is filbert or canescence squama macule by the chronic fungal infection of skin superficial due to circle or oval pityrosporum furfur.Clinical manifestation is morbidity in summer, and winter, concealment, was apt to occur in the abundant positions of sweat gland such as thoracic dorsal, oxter, face neck.
Pityriasis rosea is that a kind of common self limiting inflammatory skin is sick.In clinical manifestation, skin lesion is oval or circular rose-colored macule, its major axis is consistent with dermatoglyph trend, some skin lesion ringwise, surface is covered with bran shape squama, be apt to occur in trunk and extremity near-end, be dispersed in distribution, conscious pruritus in various degree, some patients were is with upper respiratory tract infection symptoms such as general malaise, headache, pharyngalgia.
Anaphylactoid purpura is immunoglobulin A, C 3at small artery, blood capillary and venular a kind of polyangitis, take skin purpura, arthritis, stomachache, hematuria is main manifestations, is in most cases a kind of optimum self-limited disease with immune complex deposit.The positive sign of anaphylactoid purpura can comprise: the purpura of protuberance surface, and particularly common at buttocks and shank, hands, foot, ear and scalp edema, arthritis, knee and ankle are the most common.
Seborrheic dermatitis (traditional Chinese medical science has another name called dandruff wind) is to occur in a kind of chronic pimple squama inflammatory skin disease that sebaceous gland is enriched position.Conventionally at head, start to spread downwards to other seborrhea positions, with pruritus in various degree, adult and neonate are common.The positions such as skin lesion mainly appears at after scalp, geisoma, nasolabial fold, buccal, ear, upper breast.Show as more clearly, the slightly yellowy kermesinus patch of boundary, on it, cover greasy squama or crust., there is again the skin lesion of trunk often in the form of a ring in conscious slight pruritus.
Ichthyosis (being commonly called as pityriasis), 70% belongs to heredity, during more than child, falls ill, predilection site extremity trunk is faced upward, xerosis cutis is coarse, the slightly perk of scurf edge, and shape is like Periostracum Serpentis, or fine hair hole has particulate matter to stop up, can not grow fine hair, severe one skin becomes taupe squama and very grave speckle, along with the age increases the dirty whole body that involves, the heavy summer in primary disease feature winter is light, is a kind of common heritability Keratoderma dermatoses.
Summary of the invention
The object of this invention is to provide a kind of dermopathic Chinese medicine composition that is used for the treatment of.
Meanwhile, the present invention also provides a kind of preparation method that is used for the treatment of dermopathic Chinese medicine composition.
In order to realize above object, the technical solution adopted in the present invention is:
Be used for the treatment of a dermopathic Chinese medicine composition, comprise the raw material of following parts by weight: 80~120 parts of Radix Polygoni Multiflori, 40~60 parts of Fructus Psoraleaes, 5~10 parts of Solenognathus, 15~20 parts of Hippocampus, 40~60 parts of Semen Cuscutae, 20~40 parts of Radix Saposhnikoviaes, 20~40 parts of the Cortexs Eucommiae, 1~3 part of Scolopendra, 20~40 parts of Radix Angelicae Pubescentiss, 30~50 parts of Zaocyss, 30~50 parts of Radix Salviae Miltiorrhizaes, 20~40 parts of Bombyx Batryticatus, 50~70 parts of Herba Ecliptaes, 20~40 parts of the Radixs Angelicae Dahuricae, 50~70 parts of the Radixs Astragali, 40~60 parts of Radix Et Caulis Acanthopanacis Senticosis.
Preferably, be a kind ofly used for the treatment of dermopathic Chinese medicine composition, also comprise the raw material of following parts by weight: 450~500 parts of Flos Sophorae Mel.
Be used for the treatment of a dermopathic Chinese medicine composition, also comprise the adjuvant of following parts by weight: 10~15 parts of microcrystalline Cellulose, 10~15 parts of lactose, 10~15 parts of calcium hydrogen phosphate.
Each crude drug effect is summarized as follows:
Radix Polygoni Multiflori: be the tuber of Polygonaceae arsesmart Radix Polygoni Multiflori; Contain anthraquinone analog compound as various active compositions such as emodin, chrysophanol, chrysophanic acid anthrone, Radix Polygoni Multiflori the third element, piceids; Nature and flavor are bitter, sweet, puckery, and tepor, returns liver, the heart, kidney channel; Can nourishing the blood and yin, loosening bowel to relieve constipation, dispel the wind, detoxify; Cure mainly Light-headedness, cardiopalmus, insomnia, soreness of the waist and knees, early whitening of beard and hair, tinnitus, dryness of the intestine constipation, chronic malaria body void, rubella pruritus, carbuncle sore, scrofula etc.; Modern pharmacology proof Radix Polygoni Multiflori has the effects such as blood fat reducing, atherosclerosis, enhancing immunity, slow down aging, anti-genetic damage, antiinflammatory, analgesia.
Fructus Psoraleae: be the fruit of pulse family Psoralea plant Fructus Psoraleae, contain Coumarins as psoralen, isopsoralen (being Radix Angelicae Dahuricae element), xanthotoxin, psoralidine, isopsoralidine, Psoralen, Fructus Psoraleae tonkabean oestrane A and B, neo-psoralen etc., Flavanones is as Fructus Psoraleae flavanone, different Fructus Psoraleae flavanone, Fructus Psoraleae flavanone methyl ether etc., chalcone is as Corylifolinin, Bavachalcone, bavachromene etc., monoterpene phenols is as Bakuchiol, also contain Fructus Psoraleae polysaccharide and potassium, manganese, calcium, ferrum, copper, zinc, the elements such as antimony, fatty acid is as Palmic acid, oleic acid, linoleic acid, stearic acid, the various active compositions such as linolenic acid, nature and flavor acrid, bitter, warm, returns kidney, spleen channel, energy reinforcing the kidney and supporting YANG, warm spleen antidiarrheal, cure mainly sweating due to debility lumbago, chronic diarrhea, breathe heavily void, vitiligo, alopecia areata, psoriasis etc., modern pharmacology proof Fructus Psoraleae has the effects such as antitumor, short melanin generation, antipathogen.
Solenognathus: for Syngnathidae solenognathus hardwickii belongs to animal solenognathus hardwickii, syngnathoides biaculeatus belongs to all of the multiple Solenognathus such as animal syngnathoides biaculeatus, Syngnathus animal syngnathus acus Linnaeus or removes all of epithelium and internal organs; Syngnathus acus Linnaeus, containing cholesterol, 4-cholestene-3-ketone, N-phenyl-β-aniline, also contains the various active compositions such as myristic acid, Palmic acid, stearic acid; Nature and flavor are sweet, salty, warm, return liver, kidney channel; Energy kidney invigorating and YANG supporting, mass dissipating and swelling eliminating; Curing mainly suffers from a deficiency of the kidney makes Chuan, lumps in the chest and abdomen, scrofula goiter, traumatic injury, carbuncle furuncle etc.; Modern pharmacology proof Solenognathus has gonadotropic Effect, and immune system is had to facilitation etc.
Hippocampus: for the multiple Hippocampus such as Syngnathidae Hippocampus animal hippocampus kelloggi Jordan et Snyder, HIPPOCAMPUS, large Hippocampus, hippocampus trimaculatus Leacs, little Hippocampus are removed all of internal organs; Hippocampus trimaculatus Leacs contains 17 seed amino acids such as glutamic acid, aspartic acid, glycine, proline, alanine, leucine, also contains 19 kinds of inorganic elementss such as calcium, phosphorus, sodium, potassium, magnesium, ferrum, strontium, and stearic acid, cholesterol isoreactivity composition; HIPPOCAMPUS contains protein, fat and several amino acids, flavedo element, for gamma carotene, red pigment are astaxanthin, astacene and melanin, also contains the various active compositions such as Paeonolum, cholesterol, Cholesteryl stearate, acetylcholinesterase, protease; Large Hippocampus contains more than 20 seed amino acids such as arginine, aspartic acid, alanine, glycine, proline, also contain taurine that medical value is higher and a large amount of calcium, magnesium, potassium, sodium, ferrum, the inorganic elements such as more zinc, manganese, copper and a small amount of chromium, cobalt, selenium, lead; Nature and flavor are sweet, salty, warm, return liver, kidney channel; Energy kidney invigorating and YANG supporting, mass dissipating and swelling eliminating; Cure mainly and suffer from a deficiency of the kidney, breathe heavily Xu, lumps in the chest and abdomen, traumatic injury, carbuncle furuncle etc.; Modern pharmacology proof Hippocampus has slow down aging, antithrombotic, resisting fatigue, antitumor and estrogen-like effects etc.
Semen Cuscutae: be the seed of Convolvulaceae Hellweed Semen Cuscutae; Seed contains flavonoid as Quercetin, Herba Astragali Melilotoidis (Herba Astragali Sinici) glycosides, hyperin etc.; South Semen Cuscutae fruit contains a large amount of alkaloids, seed contains new Semen Sesami ester element, Palmic acid, stearic acid, daucosterol and sterols as cupreol, stigmasterol, 5-avenasterol etc., flavonoid, as kaempferol, Herba Astragali Melilotoidis (Herba Astragali Sinici) glycosides, Quercetin, lacceroic acid etc., also contains the various active compositions such as southern Semen Cuscutae glycosides A, thymidylic acid, caffeic acid, p-hydroxycinnamic acid; Nature and flavor are pungent, sweet, flat, return liver,kidney,spleen warp; Can the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, the stopping leak that begins admittedly; Cure mainly soreness of waist and knee joint, blurred vision tinnitus, have loose bowels etc.; The modern pharmacology proof Cortex Eucommiae has and strengthens the effects such as immune, anticancer.
Radix Saposhnikoviae: be the root of Umbelliferae Radix Saposhnikoviae platymiscium Radix Saposhnikoviae; Contain chromone constituents as Radix Saposhnikoviae chromone alcohol etc., Coumarins composition is as bergapten, psoralen, phellopterin etc., polyacetylene constituents is as Panaxynol etc., polysaccharide component is as Radix Saposhnikoviae acidic polysaccharose A, C, volatile oil, as octanal etc., also contains the plurality of active ingredients such as cupreol, vanillic acid, wogonin; Windproof acrid in the mouth, sweet, tepor, return bladder, lung, spleen channel; Energy expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion, antipruritic; Cure mainly that affection of exogenous wind-cold, migraine and general headache, rheumatic arthralgia, stomachache are had loose bowels, discharging fresh blood stool, tetanus, infantile convulsion, kite pruritus, skin infection from the beginning of etc.; Modern pharmacology proof Radix Saposhnikoviae has the effects such as antipyretic cooling, analgesia, calmness, convulsion, antiinflammatory, antibacterial, antitumor.
The Cortex Eucommiae: be the bark of the Eucommiaceae Cortex Eucommiae platymiscium Cortex Eucommiae, contain multiple lignanoid and methods of glycosides thereof, as dextrorotation syringaresinol, dextrorotation syringaresinol glucoside, dextrorotation pinoresinol, dextrorotation table pinoresinol etc., also contain flavonoid as kaempferol, Quercetin, quercetin-3-O-BETA-D-glucopyranosid, Herba Astragali Melilotoidis (Herba Astragali Sinici) glycosides etc., iridoids is as aucubin, Cortex Eucommiae glycosides, ajugoside, eucommoil, eucommioside etc., phenolic constituent is as caffeic acid, chlorogenic acid, methyl chlorogenate, vanillic acid etc., Triterpenoid is as betulin, betulic acid, ursolic acid etc., and phenylalanine, lysine, tryptophan, methionine, threonine, 17 kinds of free amino acids such as valine and germanium, 15 kinds of trace element such as selenium, nature and flavor are sweet, micro-pungent, warm, return liver, kidney channel, energy invigorating the liver and kidney, bone and muscle strengthening, cure mainly soreness of waist and knee joint, rheumatic arthralgia etc., the modern pharmacology proof Cortex Eucommiae has blood pressure lowering, strengthens the effects such as immunity.
Scolopendra: for Scolopendridae Scolopendra animal is lacked all of sour jujube Scolopendra and Scolopndra subspinipes multidens (Newport); Few sour jujube Scolopendra Scorpio contains two kinds like the toxic component of Venenum apis, be histamine sample material and hemolytic protein, also contain fatty oil, cholesterol, formic acid etc., another containing ornithine, taurine, aspartic acid, threonine, serine, glutamic acid, glycine etc., and 28 kinds of inorganic elements isoreactivity compositions such as phosphorus, potassium, sodium, calcium, magnesium; Scolopndra subspinipes multidens (Newport) Scorpio contains class Venenum apis sample and analogued histamine sample material, dissolved blood protein, also contains fat, formic acid etc.; Exocuticula is containing chitin, chitan, glucamine, acid phosphatase, beta-carotene, astaxanthin ester etc., and 15 kind fatty acids (ten tetra-carbonics, ten five carbonic acid, Palmic acid, ten seven carbonic acid, oleic acid, linoleic acid etc.) the isoreactivity composition identical with few sour jujube Scolopendra; Nature and flavor are pungent, warm, return Liver Channel; Can dispel the wind, arresting convulsion, counteracting toxic substances, eliminating stagnation; Cure mainly apoplexy, infantile convulsion, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom; Modern pharmacology proof Scolopendra has the effects such as slow down aging, antiinflammatory, analgesia, antibacterial, antitumor, convulsion.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel; Contain coumarin kind compound as columbianetin and acetas thereof, osthole, different imperatorin, bergapten, xanthotoxin, Angelica pubescens alcohol etc., volatile oil is as various active compositions such as Buddhist art alkene, thymol, p-methyl phenol, β-cedrenes; Nature and flavor are bitter, pungent, tepor, return kidney, urinary bladder channel; Energy expelling wind and dampness, dispersing cold for relieving pain; Cure mainly anemofrigid-damp arthralgia, lumbocrural pain, headache toothache etc.; Modern pharmacology proof Radix Angelicae Pubescentis has analgesia, calmness, antiinflammatory, spasmolytic, antitumor, the effect such as antibacterial.
Zaocys: remove all of internal organs for the Colubridae crow tip belongs to animal Zaocys; Contain 17 seed amino acids such as lysine, leucine, aspartic acid, glutamic acid, glycine, alanine, threonine, serine, cystine, valine, methionine, isoleucine, tyrosine, phenylalanine, histidine, arginine, proline; Nature and flavor are sweet, flat, return lung, spleen, Liver Channel; Energy wind-damp dispelling, the meridian dredging, relieving convulsion; Cure mainly rheumatoid arthritis stubborn, numbness of the skin, the contracture of muscle arteries and veins, quadriplegia, tetanus, leprosy, rubella scabies; Modern pharmacology proof Zaocys has the effects such as arthritis, anti-inflammatory and antalgic, convulsion, venom.
Radix Salviae Miltiorrhizae: be the root of Labiatae salvia Radix Salviae Miltiorrhizae; Contain quinones as TANSHINONES, Radix Salviae Miltiorrhizae ketolide, water-soluble phenolic compounds is as salvianolic acid, protocatechuic acid, and fatty acid, as linolenic acid, linoleic acid, also contains the various active compositions such as baicalin, daucosterol; Nature and flavor are bitter, are slightly cold, and GUIXIN, pericardium, Liver Channel; Energy blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle; Cure mainly that menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swell and ache, traumatic injury, thermal man's nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.; Modern pharmacology proof Radix Salviae Miltiorrhizae exerts an influence to cardio-cerebrovascular, respiratory system, blood fat and atherosclerosis, liver, tumor and immunologic function etc., also has the effects such as antiinflammatory, antiallergic, anti-gastric-ulcer.
Bombyx Batryticatus: the larva that belongs to animal bombyx mori for Bombycidae silkworm infects the ossified Scorpio of muscardine; Contain protein, ammonium oxalate, and 17 seed amino acids such as lysine, leucine, aspartic acid, and 28 kinds of elements such as magnesium, calcium, zinc, the plurality of active ingredients such as abnormal active stimulin, ecdysone also contained; Nature and flavor are pungent, salty, flat, return liver, lung, stomach warp; Can expelling wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat; Cure mainly infantile convulsion and twitch, apoplexy facial hemiparalysis, migraine and general headache, laryngopharynx swelling and pain, scrofula, mumps, rubella, sore; Modern pharmacology proof Bombyx Batryticatus has the effects such as convulsion, calmness, anticoagulation, blood sugar lowering.
Flos Sophorae: be the flower and alabastrum of cassia leguminous plant Chinese scholartree; The main triterpene saponin that contains is as Semen Phaseoli saponin i, II, V, Sayasaponin Ⅰ III and kaikasaponin I, II, III, flavonoid is as Quercetin, rutin, isorhamnetin, rutinoside etc., containing betulin, sophoradiol, in caul-fat, contain fatty acid and the cupreol isoreactivity compositions such as lauric acid, dodecenoic acid, myristic acid, tetradecenoic acid, Palmic acid, stearic acid, arachidic acid again; Nature and flavor are bitter, be slightly cold, and return liver, large intestine channel; Energy cooling blood for hemostasis, liver heat removing and eyesight improving; Cure mainly discharging fresh blood stool, hemorrhoid hematochezia, dysentery with red and white feces, stranguria with blood, haematemesis, epistaxis, sore swollen toxin etc., and can prevention of stroke; The effects such as that modern pharmacology proof Flos Sophorae has is antibacterial, blood coagulation, hemostasis.
Flos Sophorae Mel: Flos Sophorae Mel is honey kind in spring, the micro-Huang of color and luster, sweet matter thickness, just, delicate fragrance is micro-pungent, is difficult for crystallization for fragrant taste; Property is refrigerant, there is the damp eliminating diuresis of Flos Sophorae, the effect of cooling blood for hemostasis, can keep the normal resistivity of blood capillary, have vasodilator, improve blood circulation, treatment of vascular sclerosis, reduce the effects such as blood fat and blood pressure, and for prevention of stroke, the effect that also has heat clearing away invigorating middle warmer, removing toxic substances to moisturize simultaneously; Informal dress Flos Sophorae Mel can improve people's emotion, reaches mind tranquilizing and the heart calming effect; In honey, contain robinin and volatile oil, can antibacterial, anticorrosion and cough-relieving, the effects such as another tool heat-clearing and toxic substances removing, wrinkle removal speckle removing, skin care healthy energy, resolving depression dredging collateral; Modern medicine clinical practice proves, Mel can absorb by facilitating digestion, appetite stimulator, and calming soporific, improves Abwehrkraft des Koepers, to promoting the growth promoter of infant to have positive role; Directly external application or smear of Flos Sophorae Mel, is used for the treatment of knife injury, wound and burn and scald, is a kind of natural cosmetic good merchantable brand, to epiderm skin, its direct Nutrition of corium, can promote cell newborn, strengthens the metabolism ability of skin; Simultaneously Flos Sophorae Mel can coordinating the actions of various ingredients in a prescription, improves the property of medicine.
Herba Ecliptae (Herba Tropaeoli): be the herb of Tropaeolaceae nasturtium nasturtium; Seed is containing nasturtium glycosides, benzyl isothiocyanate etc., and quintessence oil is containing benzyl thiocyanate, and stem and leaf is containing isoquercitrin, Quercetin-3-tri-glucose glycosides, chlorogenic acid; Flower is containing Kaempferol Glucoside, and containing multiple carotene, phylloxanthin, zeaxanthine, alpha-carotene, beta-carotene, herb is containing lignin, nasturtium thioglycoside isoreactivity composition; Nature and flavor are pungent, sour, cool; Energy heat-clearing and toxic substances removing, cooling blood for hemostasis; Cure mainly conjunctival congestion and swelling pain, furuncle, haematemesis, spitting of blood; Modern pharmacology proof Herba Tropaeoli has the effects such as antibacterial, short cardiovascular diastole.
The Radix Angelicae Dahuricae: be the root of the Umbelliferae archangel Radix Angelicae Dahuricae and Radix angelicae dahuricae; Contain Coumarins as imperatorin, different imperatorin etc., phellopterin, byak-angelicins etc., also contain coumarin glucose glycoside as various active compositions such as nodakenins; Nature and flavor are pungent, and temperature is returned lung, spleen, stomach warp; Energy expelling wind and removing dampness, understand things pain-stopping, detumescence and apocenosis; Cure mainly headache due to common cold, supraorbital bone pain, ulcer sores etc., the modern pharmacology proof Radix Angelicae Dahuricae has the effects such as antalgic and sedative, antipyretic and anti-inflammatory, inhibition tumor, antimicrobial, can also anticoagulant, coronary artery dilating, excited respiratory center etc.
The Radix Astragali: be the root of pulse family Astragalus Radix Astagali and Radix Astragali; Contain saponin component as astragaloside, isoflavones components is as calycosin, and fatty acid is as Palmic acid and linoleic acid, and polysaccharide is as astragalus polysaccharides, heteropolysaccharide etc., and nearly 20 various trace elements; Radix Astragali nature and flavor are sweet, and temperature is returned lung, spleen channel; Energy benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; Cure mainly the disease of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts and do not hold back for a long time; The modern pharmacology proof Radix Astragali can affect organism metabolism to be had antioxidation, antithrombotic, antiviral, arthritis, anticancer, anti-inflammatory and antalgic, protection cardio-cerebrovascular and promotes hemopoietic function etc.
Radix Et Caulis Acanthopanacis Senticosi: be root, rhizome or the stem and leaf of studies on plants of Acanthopanax Miq. in Araliaceae Radix Et Caulis Acanthopanacis Senticosi; Root contains eleutheroside A, B, B1, C, D, E, sinapyladehyde glucoside, coniferyl aldehyde glucoside, laricin, vanillin, syringic acid, vanillic acid, ferulic acid, chlorogenic acid and water solublity Radix Et Caulis Acanthopanacis Senticosi polysaccharide PES-A, PES-B etc., peel of stem contains ligustrin, chlorogenic acid etc., leaf contains triterpene saponin as Radix Et Caulis Acanthopanacis Senticosi glucoside I, K, L, M, also contain phenolic glycoside class as ciwujiatone, neolignans is as neociwujiaphenol, and bark contains the various active compositions such as PCA; Nature and flavor are pungent, warm, return liver, kidney channel; Can QI invigorating, the kidney invigorating, calm the nerves, invigorate blood circulation; Cure mainly insufficiency of the spleen weak, deficiency of vital energy edema, insomnia and dreamful sleep, forgetful, soreness of the waist and knees, thoracic obstruction pain, chronic cough, rheumatic arthralgia etc.; Modern pharmacology proof Radix Et Caulis Acanthopanacis Senticosi has the effects such as antiinflammatory, antitumor, antibacterial, antiviral, slow down aging, and central nervous system, cardiovascular system, hormonal system, respiratory system and immunologic function are had to regulating action.
Be used for the treatment of a dermopathic Chinese medicine composition, can adopt conventional method to be prepared into the regular dosage forms such as granule, powder, tablet, cream, honeyed pill.The present invention only provides respectively the preparation method of a kind of sweet cream and granule.
A kind of preparation method that is used for the treatment of dermopathic Chinese medicine composition, comprise the following steps: according to parts by weight, get each raw material, first by Radix Polygoni Multiflori, Fructus Psoraleae, Solenognathus, Hippocampus, Semen Cuscutae, Radix Saposhnikoviae, the Cortex Eucommiae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi crushed after being dried to 20~40 order, merging filtrate concentrated after extracting in water, concentrated solution is joined in Flos Sophorae Mel, endure to dripping into pearl and obtain sweet cream.
Described Radix Polygoni Multiflori steams to black after soaking with yellow wine, and after Solenognathus, Hippocampus cutting, processed with vinegar is to crisp, and the Cortex Eucommiae is fried to pitchy, and Semen Cuscutae is fried to yellow, and Bombyx Batryticatus is with stir-frying with ginger juice to yellow standby, and above-mentioned Chinese medicine processing method is conventional method.
The method of described extracting in water is: add for the first time 10 times of water gagings and decoct 1~1.5 hour, add for the second time 8 times of water gagings and decoct 1 hour, add for the third time 8 times of water gagings and decoct 0.5~1 hour.
Described sweet cream is labeling, vanning after fill, autoclaving.
A kind of preparation method that is used for the treatment of dermopathic Chinese medicine composition, comprise the following steps: according to parts by weight, get each raw material, first by Radix Polygoni Multiflori, Fructus Psoraleae, Solenognathus, Hippocampus, Semen Cuscutae, Radix Saposhnikoviae, the Cortex Eucommiae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi crushed after being dried to 20~40 order, merging filtrate concentrated after extracting in water, adds and granulates after microcrystalline Cellulose, lactose, calcium phosphate and obtain granule.
Described Radix Polygoni Multiflori steams to black after soaking with yellow wine, and after Solenognathus, Hippocampus cutting, processed with vinegar is to crisp, and the Cortex Eucommiae is fried to pitchy, and Semen Cuscutae is fried to yellow, and Bombyx Batryticatus is with stir-frying with ginger juice to yellow standby, and above-mentioned Chinese medicine processing method is conventional method.
The method of described extracting in water is: add for the first time 10 times of water gagings and decoct 1~1.5 hour, add for the second time 8 times of water gagings and decoct 1 hour, add for the third time 8 times of water gagings and decoct 0.5~1 hour.
Usage and consumption:
Honey cream (for oral administration and/or external): for oral administration, each 30g, every day three times, child is cut down according to the circumstance; The outer used time adds sweet cream in white vinegar and dilutes, and is applied in sufferer skin after mixing, every day twice, and each 1~2 spoonful, to impel skin lesion and patch healing to dissolve.
Granule (for oral administration and/or external): for oral administration, each 15g, every day three times, child is cut down according to the circumstance; The outer used time, is dissolved in drug particles in white vinegar, every day 2~3 times, mixes rear even wiping in sufferer skin, 3~5 minutes, is beneficial to drug absorption.
Beneficial effect of the present invention:
The present invention is according to theory of Chinese medical science, according to monarch principle composition of prescription, select Radix Polygoni Multiflori, Fructus Psoraleae, Solenognathus, Hippocampus, Semen Cuscutae, Radix Saposhnikoviae, the Cortex Eucommiae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi totally 16 taste pure natural Chinese herbal medicine, all medicines share the effect such as have enriching yin and nourishing kidney, dispelling wind is invigorated blood circulation, after composite with Flos Sophorae Mel, make sweet cream, or with the agent of auxiliary materials and mixing granulation; Be mainly used in treating vitiligo, also can be used for tinea versicolor, pityriasis rosea, anaphylactoid purpura, seborrheic dermatitis and ichthyosis.In side, Radix Polygoni Multiflori, Fructus Psoraleae, Semen Cuscutae, the Cortex Eucommiae are monarch drug, have the effect of enriching yin and nourishing kidney, enhancing immunity, for the deficiency of the liver and kindey day after tomorrow; Solenognathus, Hippocampus, Radix Saposhnikoviae are ministerial drug, have the effect that dispelling wind is invigorated blood circulation; Scolopendra is adjuvant drug, has the effect of dispelling wind and removing obstruction in the collateral; All the other are for making medicine.Above-mentioned all medicines are aided with the moist skin of Flos Sophorae Mel, extra-nutrition again, to reach rehabilitation object.
The present invention is prepared into sweet cream or granule by above-mentioned Chinese medicine composition, be convenient to for oral administration and external (a side is dual-purpose), and preparation method is simple, and cost is low, is suitable for suitability for industrialized production and application.
The specific embodiment
Following embodiment is only described in further detail the present invention, but does not form any limitation of the invention.
Embodiment 1
In the present embodiment, be used for the treatment of dermopathic Chinese medicine composition, by the raw material of following total amount umber, formed: 80 parts of Radix Polygoni Multiflori, 60 parts of Fructus Psoraleaes, 5 parts of Solenognathus, 20 parts of Hippocampus, 40 parts of Semen Cuscutae, 40 parts of Radix Saposhnikoviaes, 20 parts of the Cortexs Eucommiae, 3 parts of Scolopendras, 20 parts of Radix Angelicae Pubescentiss, 50 parts of Zaocyss, 30 parts of Radix Salviae Miltiorrhizaes, 40 parts of Bombyx Batryticatus, 50 parts of Herba Ecliptaes, 40 parts of the Radixs Angelicae Dahuricae, 50 parts of the Radixs Astragali, 60 parts of Radix Et Caulis Acanthopanacis Senticosis, 500 parts of Flos Sophorae Mel.
The preparation method that is used for the treatment of dermopathic Chinese medicine composition in the present embodiment, comprises the following steps:
(1) according to parts by weight, get each raw material, its Radix Polygoni Multiflori steams to black standby after soaking with yellow wine;
(2) get respectively after Solenognathus, Hippocampus cutting processed with vinegar to crisp standby;
(3) getting the Cortex Eucommiae fries to pitchy standby;
(4) getting Semen Cuscutae fries to yellow standby;
(5) extremely yellow is standby with stir-frying with ginger juice to get Bombyx Batryticatus;
(6) get above-mentioned standby raw material, after mixing with Radix Saposhnikoviae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi, be crushed to 40 orders, extracting in water, adding for the first time 10 times of water gagings decocts 1.5 hours, adding for the second time 8 times of water gagings decocts 1 hour, add for the third time 8 times of water gagings and decoct 0.5 hour, concentrated standby after merging filtrate;
(7) Flos Sophorae Mel is added and in heat pot, practice ripely, add concentrated solution, the value of enduring is dripped into pearl and is obtained sweet cream.
Usage and consumption are the same.
Embodiment 2
In the present embodiment, be used for the treatment of dermopathic Chinese medicine composition, by the raw material of following total amount umber, formed: 100 parts of Radix Polygoni Multiflori, 50 parts of Fructus Psoraleaes, 7 parts of Solenognathus, 17 parts of Hippocampus, 30 parts of Radix Saposhnikoviaes, 30 parts of the Cortexs Eucommiae, 2 parts of Scolopendras, 30 parts of Radix Angelicae Pubescentiss, 40 parts of Zaocyss, 40 parts of Radix Salviae Miltiorrhizaes, 30 parts of Bombyx Batryticatus, 60 parts of Herba Ecliptaes, 30 parts of the Radixs Angelicae Dahuricae, 60 parts of the Radixs Astragali, 50 parts of Radix Et Caulis Acanthopanacis Senticosis, 470 parts of Flos Sophorae Mel.
The preparation method that is used for the treatment of dermopathic Chinese medicine composition in the present embodiment, comprises the following steps:
(1) according to parts by weight, get each raw material, its Radix Polygoni Multiflori steams to black standby after soaking with yellow wine;
(2) get respectively after Solenognathus, Hippocampus cutting processed with vinegar to crisp standby;
(3) getting the Cortex Eucommiae fries to pitchy standby;
(4) getting Semen Cuscutae fries to yellow standby;
(5) extremely yellow is standby with stir-frying with ginger juice to get Bombyx Batryticatus;
(6) get above-mentioned standby raw material, after mixing with Radix Saposhnikoviae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi, be crushed to 40 orders, extracting in water, adding for the first time 10 times of water gagings decocts 1 hour, adding for the second time 8 times of water gagings decocts 1 hour, add for the third time 8 times of water gagings and decoct 0.5 hour, concentrated standby after merging filtrate;
(7) Flos Sophorae Mel is added and in heat pot, practice ripely, add concentrated solution, the value of enduring is dripped into pearl and is obtained sweet cream.
Usage and consumption are the same.
Embodiment 3
In the present embodiment, be used for the treatment of dermopathic Chinese medicine composition, by the raw material of following total amount umber, formed: 120 parts of Radix Polygoni Multiflori, 40 parts of Fructus Psoraleaes, 10 parts of Solenognathus, 15 parts of Hippocampus, 60 parts of Semen Cuscutae, 20 parts of Radix Saposhnikoviaes, 40 parts of the Cortexs Eucommiae, 1 part of Scolopendra, 40 parts of Radix Angelicae Pubescentiss, 30 parts of Zaocyss, 50 parts of Radix Salviae Miltiorrhizaes, 20 parts of Bombyx Batryticatus, 70 parts of Herba Ecliptaes, 20 parts of the Radixs Angelicae Dahuricae, 70 parts of the Radixs Astragali, 40 parts of Radix Et Caulis Acanthopanacis Senticosis, 12 parts of microcrystalline Cellulose, 15 parts of lactose, 10 parts of calcium hydrogen phosphate.
The preparation method that is used for the treatment of dermopathic Chinese medicine composition in the present embodiment, comprises the following steps:
(1) according to parts by weight, get each raw material, its Radix Polygoni Multiflori steams to black standby after soaking with yellow wine;
(2) get respectively after Solenognathus, Hippocampus cutting processed with vinegar to crisp standby;
(3) getting the Cortex Eucommiae fries to pitchy standby;
(4) getting Semen Cuscutae fries to yellow standby;
(5) extremely yellow is standby with stir-frying with ginger juice to get Bombyx Batryticatus;
(6) get above-mentioned process of preparing Chinese medicine raw material, after mixing with Radix Saposhnikoviae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi, be crushed to 40 orders, extracting in water, adding for the first time 10 times of water gagings decocts 1 hour, adding for the second time 8 times of water gagings decocts 1 hour, add for the third time 8 times of water gagings and decoct 0.5 hour, concentrated standby after merging filtrate;
(7) in concentrated solution, add microcrystalline Cellulose, lactose, calcium phosphate, mix rear granulation and obtain granule.
Usage and consumption are the same.
Test example
Get 160 examples and make a definite diagnosis patients with vitiligo, the sweet cream of the also external embodiment of the present invention for oral administration 1,2 preparations, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with being evenly applied in affected part after white vinegar dilution.Statistics is cured, effective, effective and invalid number, calculates cure rate and total effective rate, the results detailed in following table 1.
Get 70 examples and make a definite diagnosis tinea versicolor patient, the sweet cream of the also external embodiment of the present invention for oral administration 2 preparations, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with being evenly applied in affected part after white vinegar dilution.Statistics is cured, effective, effective and invalid number, calculates cure rate and total effective rate, the results detailed in following table 1.
Get 30 examples and make a definite diagnosis pityriasis rosea patient, the granule of the also external embodiment of the present invention for oral administration 3 preparations, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, is evenly applied in affected part, wiping is 3~5 minutes repeatedly.Statistics is cured, effective, effective and invalid number, calculates cure rate and total effective rate, the results detailed in following table 1.
Get 110 examples and make a definite diagnosis the patient of seborrheic dermatitis, sweet cream for oral administration and prepared by the external embodiment of the present invention 1,2, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with being evenly applied in affected part after white vinegar dilution, statistics is cured, effective, effective and invalid number, calculates cure rate and total effective rate, the results detailed in following table 1.
Get 20 examples and make a definite diagnosis ichthyotic patient, the granule of the also external embodiment of the present invention for oral administration 3 preparations, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, is evenly applied in affected part, wiping is 3~5 minutes repeatedly.Statistics is cured, effective, effective and invalid number, calculates cure rate and total effective rate, the results detailed in following table 1.
Vitiligo curative effect determinate standard (referring to < < China Dermatology magazine > >):
Cure: mottle all disappears, or tip end is with pigmentation;
Effective: Stain removal is more than 85%, or be obviously furnished with black pigment island;
Effective: Stain removal is below 30%;
Invalid: skin splash is not seen reaction or the trend of not feeling any better.
Other disease curative effect determinate standards:
Cure: skin lesion all disappears;
Effective: skin lesion is eliminated more than 85%;
Effective: skin lesion is eliminated below 30%;
Invalid: skin lesion is not seen reaction or the trend of not feeling any better.
Each treatment group curative effect statistics of table 1
Group Healing/example Effective/example Effectively/example Invalid/example Cure rate/% Total effective rate/%
Vitiligo 55 76 29 / 34.4 100
Tinea versicolor 75 / / / 100 100
Pityriasis rosea 25 5 / / 83.3 100
Seborrheic dermatitis 36 20 49 5 32.7 95
Ichthyosis 18 1 1 / 90 100
As shown in Table 1, the Chinese medicine of the embodiment of the present invention 1~3 preparation reaches more than 30% leukodermic cure rate, total effective rate is 100%, cure rate to tinea versicolor reaches 100%, and the cure rate of pityriasis rosea is reached more than 80%, and total effective rate is 100%, the cure rate of seborrheic dermatitis is reached more than 30%, total effective rate is 95%, and ichthyotic cure rate is reached to 90%, and total effective rate is 100%.During medication, all patients are showed no any untoward reaction.
Model case
Case 1: Wang, female, 12 years old, through hospital, be diagnosed as vitiligo, hospitalization three months is ineffective, the state of an illness has development trend, then medical, see that patient has more than 20 white maculas of locating to differ in size all over the body, the sweet cream of preparing with the external embodiment of the present invention 1 for oral administration, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with being evenly applied in affected part after white vinegar dilution, after medication 40 days, 2/3 before seeing that lesions of patients tapers to, Semen Sesami size pigment island is seen in affected part, continue medication 3 months, white macula all disappears.
Case 2: Zhang, man, 42 years old, affected part is clashed in readme cause in January agriculture business accidentally, the existing beans sample white point in affected part after two weeks, increase thereupon, then medical, see that patient's right lower extremity has the well-defined white macula of place's hand size, be white powder, no conscious sympton, be diagnosed as Secondary cases limitation vitiligo, granule for oral administration and prepared by the external embodiment of the present invention 3, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, evenly be applied in affected part, wiping is 3~5 minutes repeatedly, after medication 6 months, affected part is changed peony into by redness, occur that pigment island is to the recovery from illness that disappears.
Case 3: Lee, female, 27 years old, readme in June, 2012 waist week is several places white macula now, not medical, after 1 year, white fleck increases, and with going to a doctor, sees that patient's waist and belly has more than ten to locate white macula, no conscious sympton, be diagnosed as general property completeness vitiligo, the granule of preparing with the external embodiment of the present invention 3 for oral administration, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, is evenly applied in affected part, wiping is 3~5 minutes repeatedly, after medication 3 months, white macula disappears, and changes peony into gradually by white, and pigment merges to recovery from illness.
Case 4: Liu, female, 40 years old, through hospital, be diagnosed as anaphylactoid purpura, the treatment several months is invalid, then medical, the sweet cream of preparing with the external embodiment of the present invention 2 for oral administration, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with being evenly applied in affected part after white vinegar dilution, medication is transference cure after 20 days.
Case 5: Lee, man, 22 years old, after patient, the greyish white mottle of the first point-like in cervical region and shirtfront, does not generally itch not bitterly, slightly rubescent and itch after the sun is exposed to the sun, be diagnosed as tinea versicolor, here, takes the granule with 3 preparations of the external embodiment of the present invention orally then, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, is evenly applied in affected part, wiping is 3~5 minutes repeatedly, and medication is cured after 1 month substantially.
Case 6: high certain, female, readme before one month in shirtfront, there is pale red macule in abdominal part, extremity, there is meagre squama on surface, frequently gently itch, through being diagnosed as pityriasis rosea, the granule of preparing with the external embodiment of the present invention 3 for oral administration, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, is evenly applied in affected part, wiping is 3~5 minutes repeatedly, and medication is cured after 3 months substantially.
Case 7: Tang, man, 14 years old, now pair lower limb dermatoglyphs are coarse from childhood for patient, have crackle, and the heavy summer in winter is light, no conscious sympton, is diagnosed as congenital ichthyosis through hospital, seeks medical advice and has no resolution everywhere, then medical, the sweet cream of preparing with the external embodiment of the present invention 2 for oral administration, for oral administration: every day three times, each 30g, external: every day twice, each 1~2 spoonful, with after white vinegar dilution, be evenly applied in affected part, medication after 9 months skin transfer to normally.
Case 8: Wang, man, 54 years old, suffer from seborrheic dermatitis more than 10 years, Relapse rate, when heavy, the utmost point is itched, with alopecia, then medical, the granule of preparing with the external embodiment of the present invention 3 for oral administration, for oral administration: every day three times, each 15g, external: granule is scattered in white vinegar, evenly be applied in affected part, wiping is 3~5 minutes repeatedly, and medication is cured after 6 months substantially, follows up a case by regular visits to and within 1 year, has no recurrence.

Claims (9)

1. be used for the treatment of a dermopathic Chinese medicine composition, it is characterized in that: the raw material that comprises following parts by weight: 80~120 parts of Radix Polygoni Multiflori, 40~60 parts of Fructus Psoraleaes, 5~10 parts of Solenognathus, 15~20 parts of Hippocampus, 40~60 parts of Semen Cuscutae, 20~40 parts of Radix Saposhnikoviaes, 20~40 parts of the Cortexs Eucommiae, 1~3 part of Scolopendra, 20~40 parts of Radix Angelicae Pubescentiss, 30~50 parts of Zaocyss, 30~50 parts of Radix Salviae Miltiorrhizaes, 20~40 parts of Bombyx Batryticatus, 50~70 parts of Herba Ecliptaes, 20~40 parts of the Radixs Angelicae Dahuricae, 50~70 parts of the Radixs Astragali, 40~60 parts of Radix Et Caulis Acanthopanacis Senticosis.
2. be according to claim 1ly used for the treatment of dermopathic Chinese medicine composition, it is characterized in that: the raw material that also comprises following parts by weight: 450~500 parts of Flos Sophorae Mel.
3. be according to claim 1ly used for the treatment of dermopathic Chinese medicine composition, it is characterized in that: the adjuvant that also comprises following parts by weight: 10~15 parts of microcrystalline Cellulose, 10~15 parts of lactose, 10~15 parts of calcium hydrogen phosphate.
4. a preparation method that is used for the treatment of dermopathic Chinese medicine composition as claimed in claim 2, it is characterized in that: comprise the following steps: according to parts by weight, get each raw material, first by Radix Polygoni Multiflori, Fructus Psoraleae, Solenognathus, Hippocampus, Semen Cuscutae, Radix Saposhnikoviae, the Cortex Eucommiae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi crushed after being dried to 20~40 order, merging filtrate concentrated after extracting in water, concentrated solution is joined in Flos Sophorae Mel, endure to dripping into pearl.
5. the preparation method that is used for the treatment of dermopathic Chinese medicine composition according to claim 4, it is characterized in that: described Radix Polygoni Multiflori steams to black after soaking with yellow wine, after Solenognathus, Hippocampus cutting, processed with vinegar is to crisp, the Cortex Eucommiae is fried to pitchy, Semen Cuscutae is fried to yellow, and Bombyx Batryticatus is standby to yellow with stir-frying with ginger juice.
6. the preparation method that is used for the treatment of dermopathic Chinese medicine composition according to claim 4, it is characterized in that: the method for described extracting in water is: add for the first time 10 times of water gagings and decoct 1~1.5 hour, add for the second time 8 times of water gagings and decoct 1 hour, add for the third time 8 times of water gagings and decoct 0.5~1 hour.
7. a preparation method that is used for the treatment of dermopathic Chinese medicine composition as claimed in claim 3, it is characterized in that: comprise the following steps: according to parts by weight, get each raw material, first by Radix Polygoni Multiflori, Fructus Psoraleae, Solenognathus, Hippocampus, Semen Cuscutae, Radix Saposhnikoviae, the Cortex Eucommiae, Scolopendra, Radix Angelicae Pubescentis, Zaocys, Radix Salviae Miltiorrhizae, Bombyx Batryticatus, Herba Ecliptae, the Radix Angelicae Dahuricae, the Radix Astragali, Radix Et Caulis Acanthopanacis Senticosi crushed after being dried to 20~40 order, merging filtrate concentrated after extracting in water, granulates after adding microcrystalline Cellulose, lactose, calcium phosphate.
8. the preparation method that is used for the treatment of dermopathic Chinese medicine composition according to claim 7, it is characterized in that: described Radix Polygoni Multiflori steams to black after soaking with yellow wine, after Solenognathus, Hippocampus cutting, processed with vinegar is to crisp, the Cortex Eucommiae is fried to pitchy, Semen Cuscutae is fried to yellow, and Bombyx Batryticatus is standby to yellow with stir-frying with ginger juice.
9. the preparation method that is used for the treatment of dermopathic Chinese medicine composition according to claim 7, it is characterized in that: the method for described extracting in water is: add for the first time 10 times of water gagings and decoct 1~1.5 hour, add for the second time 8 times of water gagings and decoct 1 hour, add for the third time 8 times of water gagings and decoct 0.5~1 hour.
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CN104971263A (en) * 2015-08-05 2015-10-14 周功浪 Traditional Chinese medicine for treating leucoderma
CN105012401A (en) * 2015-08-11 2015-11-04 李荣华 Preparation for treating leucoderma and preparation method
CN105663376A (en) * 2016-01-16 2016-06-15 杜志政 Medicament for treating dermatophytosis and preparation method thereof
CN115192490A (en) * 2022-07-20 2022-10-18 广州睿森生物科技有限公司 Nano microemulsion NMN composition and preparation method and application thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971263A (en) * 2015-08-05 2015-10-14 周功浪 Traditional Chinese medicine for treating leucoderma
CN105012401A (en) * 2015-08-11 2015-11-04 李荣华 Preparation for treating leucoderma and preparation method
CN105663376A (en) * 2016-01-16 2016-06-15 杜志政 Medicament for treating dermatophytosis and preparation method thereof
CN115192490A (en) * 2022-07-20 2022-10-18 广州睿森生物科技有限公司 Nano microemulsion NMN composition and preparation method and application thereof

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