CN111773149A - Skin care composition and preparation method thereof - Google Patents

Abstract

The invention discloses a skin care composition and a preparation method thereof, the skin care composition comprises an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract, and the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 1.5-16: 1. specifically, the skin care composition can be prepared from the following components in percentage by weight: 1 to 20 percent of emollient, 0.05 to 1 percent of thickening agent, 0.5 to 5 percent of emulsifier, 0.15 to 0.5 percent of hemp flower and leaf extract, 0.03 to 0.1 percent of glycyrrhiza glabra extract, 0.1 to 1.0 percent of preservative, 0.5 to 15 percent of polyhydric alcohol, 0.02 to 0.2 percent of additive and the balance of pure water. In the skin care composition, the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract have synergistic effect, and have multiple skin care effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color, homogenizing skin color and the like.

Description

Skin care composition and preparation method thereof

Technical Field

The invention belongs to the technical field of beauty treatment, particularly relates to a skin care composition and a preparation method thereof, and more particularly relates to a skin care composition containing an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract.

Background

Has good image and is the constant pursuit of people in different generations. When people select beauty products, two points are often most concerned, namely the effect of the product and the safety of the product. In order to seek a target for a short-term effect, some cosmetic products contain substances harmful to the human body, such as hormones. The skin care product prepared by taking the plant extract as the main active ingredient has good safety and is more popular with people.

Industrial hemp, also known as hemp, hemp and Moraceae, is a tough, cold-resistant annual herb plant native to China and India and is a hemp beneficial to human beings. The industrial hemp is the traditional economic crop, but the understanding of the toxicity of the hemp crop is misleading. The toxicity of cannabis is defined by the percentage of Tetrahydrocannabinol (THC) in the dry matter of the flowers and leaves of its plant. The European Union, Canada, Australia and other countries are all defined as 0.3%, cannabis with THC content higher than 0.3% is classified as drug cannabis, cannabis with THC content lower than 0.3% is classified as industrial cannabis, and the country also executes the defined standard.

The Bama area with the country and beauty of China longevity is known as edible cannabis, and the 'cannabis soup' is popular with Bama people as the 'longevity soup'. The cannabis sativa contains abundant unsaturated low fatty acid, vegetable protein, lecithin, a large amount of microelements such as vitamin E, selenium, zinc, manganese, germanium and the like which are necessary for human bodies and are used for delaying senility, and also contains alpha-linolenic acid (ALA) which is known as 'plant brain gold', and the cannabis sativa food is a long-term eating product which is the secret place of longevity of the old in Bama and Baisui. In addition, the hemp seed refined "hemp seed oil" is the only water-soluble vegetable oil in the world, and the content of unsaturated fatty acid is far higher than that of deep sea fish oil.

Medically, industrial cannabis can relieve pain, relieve anxiety, relax spirit, regulate sleep, inhibit bacterial growth, lower blood glucose, relieve nausea, and even delay the growth of cancer tumor cells; the industrial hemp can also discharge the harmful substances such as redundant fat particles and cholesterol in the body, expel toxin and lose weight, and nourish yin and tonify the kidney.

Glycyrrhiza glabra is a plant belonging to the genus Glycyrrhiza of the family Leguminosae. The Glycyrrhrizae radix is dried root and rhizome of Glycyrrhiza glabra, Glycyrrhiza uralensis Fisch or Glycyrrhiza inflata Bat. The liquorice is one of ten bulk medicinal materials in China, is also called as the old, the Lingtong, the radix glycyrrhizae, and the like, and has the effects of tonifying spleen and qi, clearing heat and removing toxicity, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the medicines. Modern pharmacological research shows that the liquorice has the functions of resisting tumor, virus, inflammation, immunity and ulcer and protecting liver. The main chemical components of licorice are glycyrrhizic acid, glycyrrhetinic acid, glabridin, liquiritigenin, etc. and may be used widely in medicine, food, cosmetics, etc.

Glycyrrhizic acid is the main active component in liquorice, is a pentacyclic triterpenoid, has the effects of resisting tumor, virus, oxidation, inflammation and immunity regulation and the like, has low high sweetness, low heat energy, air bubble property and hemolysis, is safe and nontoxic, has strong medical care effects, is widely used in clinical medicine, and is also widely applied to the field of cosmetics besides main medicine.

The glabridin is one of main fat-soluble flavonoid components in glycyrrhiza glabra, and researches show that the glabridin has certain effects of resisting oxidation, reducing blood fat and lowering blood pressure, and also shows good research prospects in prevention and treatment of cardiovascular diseases. Glabridin has antioxidant effect, and can inhibit free radicals generated by cytochrome P450/NADPH oxidation system, thus preventing and treating pathological changes related to free radical oxidative damage, such as cell aging, atherosclerosis, etc. In addition, the glabridin also has the functions of regulating immunity, resisting bacteria and inhibiting melanogenesis, and particularly has the effect of inhibiting melanogenesis, so that the glabridin is named as 'whitening gold' in the beauty treatment world.

At present, no research and report that industrial hemp flower and leaf extract and glycyrrhiza glabra extract can play a synergistic effect and jointly prepare a skin care composition with multiple effects and good safety exists.

The present invention has been made in view of this situation.

Disclosure of Invention

The technical problem to be solved by the invention is to overcome the defects of the prior art and provide a skin care composition and a preparation method thereof, the skin care composition has multiple effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color, homogenizing skin color and the like, and the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract play a synergistic effect, so that multiple skin care effects are improved, and the safety is high.

In order to solve the technical problems, the invention adopts the technical scheme that:

the first purpose of the invention is to provide a skin care composition, which comprises an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract, wherein the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 1.5-16: 1.

the skin care composition comprises an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract, wherein the content of tetrahydrocannabinol in the industrial hemp flower and leaf extract is lower than 0.3%, and the skin care composition also contains abundant unsaturated low-fatty acid, vegetable protein, lecithin, a large amount of vitamin E, selenium, zinc, manganese, germanium and other trace elements necessary for human bodies for delaying senescence, and can achieve the effect of diminishing inflammation. The Glycyrrhiza glabra extract can resist oxidation, inhibit melanin generation, lighten spots and play a role in whitening and removing spots. In the skin care composition, the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract are reasonably compatible to play a synergistic role, so that the skin care composition not only can improve whitening, freckle removing and inflammation diminishing effects, but also can play multiple effects of removing wrinkles, brightening skin color, homogenizing skin color and the like.

In a further scheme, the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 3-8: 1;

preferably, the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 5: 1.

the applicant unexpectedly found in the experimental process that when the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 5:1, the skin care composition has good whitening, anti-inflammatory and freckle removing effects; and simultaneously, the effects of removing wrinkles, brightening skin color and homogenizing skin color are better.

In a further scheme, the skin care composition comprises the following components in percentage by weight:

in a further scheme, in the industrial cannabis sativa flower and leaf extract, the weight content of cannabidiol is more than 10%, and the weight content of tetrahydrocannabinol is less than 0.3%; preferably, the content of cannabidiol in the industrial hemp flower and leaf extract is more than 40% by weight.

Cannabidiol has antioxidant, antiinflammatory and analgesic effects. In the industrial hemp flower and leaf extract adopted by the scheme, the purity of cannabidiol is high, and the effects of oxidation resistance and inflammation diminishing can be better achieved.

In a further scheme, in the glycyrrhiza glabra extract, the weight content of glycyrrhizic acid is more than 10 percent, and the weight content of glabridin is more than 30 percent;

preferably, the glycyrrhizic acid content is greater than 25% by weight, and the glabridin content is greater than 40% by weight.

Glycyrrhizic acid is a pentacyclic triterpenoid compound, has the effects of resisting tumor, virus, oxidation and inflammation, regulating immunity and the like, has low high sweetness, low heat energy, air bubble property and hemolysis, and is safe and nontoxic. Glabridin has antioxidant effect, can inhibit free radicals generated by cytochrome P450/NADPH oxidation system, prevent and treat pathological changes related to free radical oxidative damage, and has effects of regulating immunity, resisting bacteria, and inhibiting melanogen, especially inhibiting melanogenesis. The glycyrrhiza glabra extract has high content of glycyrrhizic acid and glabridin, can perform a synergistic effect with an industrial hemp flower and leaf extract, and achieves excellent effects of removing wrinkles, diminishing inflammation, removing freckles, whitening, brightening skin color and homogenizing skin color.

Generally speaking, the industrial hemp flower and leaf extract mainly plays a role in diminishing inflammation, and the glycyrrhiza glabra extract mainly plays a role in whitening, but the invention finds that after the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract are mutually matched, not only can the whitening and anti-inflammation effects be further improved, but also the effects of removing wrinkles and brightening skin colors can be achieved; and when the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 5:1, the effect is optimal.

In a further embodiment, the emollient is selected from at least one of hemp seed oil, mineral oil, dimethicone, cetostearyl oil, shea butter, caprylic/capric triglyceride (ethylhexanoic acid) ester, isopropyl palmitate, isopropyl myristate, dioctyl carbonate, isononyl isononanoate, olive oil, jojoba oil, pentaerythritol tetrastearate.

In a further scheme, the thickening agent is at least one selected from carbomer, collagen, hydroxyethyl cellulose, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer and ammonium dimethyltaurate acrylate/VP copolymer.

In a further embodiment, the emulsifier is at least one selected from the group consisting of glyceryl stearate, PEG-100 stearate, cetearyl glucoside, ceteareth-20, lecithin, tween 20, tween 60, span 60, polyglycerol-10 myristate, and potassium cetyl phosphate.

In a further scheme, the preservative is selected from at least one of methyl paraben, propyl paraben, phenoxyethanol, chlorphenesin, p-hydroxyacetophenone and caprylhydroxamic acid;

in a further embodiment, the polyhydric alcohol is at least one selected from glycerol, propylene glycol, dipropylene glycol, alcohol, butylene glycol, pentanediol, hexanediol, octaethylene glycol, and ethylhexylglycerin;

in a further embodiment, the additive is at least one selected from EDTA-2NA, sodium hydroxide, potassium hydroxide and triethanolamine.

It should be noted that the industrial hemp flower and leaf extract and glycyrrhiza glabra extract of the present invention may be purchased as finished products or may be extracts prepared by using existing techniques or modified techniques.

As an example, the industrial hemp flower and leaf extract can be prepared by the following method, but is not limited thereto:

1) mixing hemp flower leaf powder and 85% ethanol according to a mass ratio of 1: 8 mixing, soaking at room temperature for 3 times, each time for 2 hours, mixing the extractive solutions, and recovering ethanol under reduced pressure to obtain extract;

2) mixing the hemp flower and leaf extract with 95% ethanol according to a mass ratio of 1:1, standing at-20 deg.C for 24 hr, filtering to remove insoluble substances, and recovering ethanol under reduced pressure to obtain extract. Performing macroporous resin column chromatography, collecting eluate in stages, and concentrating under reduced pressure to obtain cannabidiol concentrate;

3) mixing the extract with 75% ethanol according to a mass ratio of 1:1, mixing, performing macroporous resin column chromatography, collecting eluent in sections, and concentrating under reduced pressure to obtain cannabidiol concentrate;

4) mixing the cannabidiol concentrate with 75% of a mixture according to a mass ratio of 1:1, standing for 24 hours, and filtering to remove solids to obtain the hemp flower and leaf extract.

As an example, the glycyrrhiza glabra extract can be prepared by the following method, but is not limited thereto:

1) mixing the coarse powder of liquorice and 60% ethanol according to a mass ratio of 1: 10 mixing, extracting under reflux for 3 times, each time for 2 hours, and concentrating under reduced pressure to obtain extract;

2) performing column chromatography on the extract to obtain an eluent, and concentrating under reduced pressure to obtain a glabridin extract;

3) mixing the extract with 75% ethanol according to a mass ratio of 1:1, standing for 24 hours, and filtering to remove solids to obtain glabridin extract.

It is a second object of the present invention to provide a method of making a skin care composition according to any one or combination of the above aspects, comprising the steps of:

(1) adding polyalcohol and antiseptic into a container, heating to 60 deg.C, dissolving and dispersing;

(2) adding emollient and emulsifier into oil phase tank, heating to 80 deg.C, stirring and dispersing uniformly;

(3) adding pure water and a thickening agent into a water phase tank, heating to 80 ℃, and mixing, stirring and dispersing uniformly;

(4) adding the materials in the water phase tank into an emulsifying tank, starting a homogenizer and a stirrer, then adding the materials in the oil phase tank into the emulsifying tank in a homogenizing and stirring state, cooling after uniform emulsification and dispersion, adding the industrial hemp flower and leaf extract, the glycyrrhiza glabra extract, the additive and the polyol and the preservative which are dissolved and dispersed in advance for standby in the step (1) into the emulsifying tank when the temperature is reduced to be below 45 ℃, and uniformly stirring and dispersing to obtain the skin care composition.

In the preparation method, the raw materials are classified and processed in batches, and are uniformly stirred and dispersed at different temperatures according to the properties of the raw materials, so that the raw materials can achieve a good dispersion effect, and the obtained skin care composition is good in uniformity. Meanwhile, when the temperature of the mixture is controlled to be reduced to below 45 ℃, the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract are added, so that the loss of active ingredients at high temperature is avoided, and the composition can play the optimal effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color and homogenizing skin color.

After adopting the technical scheme, compared with the prior art, the invention has the following beneficial effects:

1. the skin care composition comprises an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract, can play a role in synergy, and has multiple effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color, homogenizing skin color and the like.

2. The content of cannabidiol in the industrial hemp flower and leaf extract and the content of glycyrrhizic acid and glabridin in the glabrous licorice extract are high, and when the industrial hemp flower and leaf extract and the glabrous licorice extract are in a reasonable mass ratio range, the effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color and homogenizing skin color are better, and especially when the mass ratio of the industrial hemp flower and leaf extract to the glabrous licorice extract is 5:1, the effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color and homogenizing skin color are best.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments will be clearly and completely described below, and the following embodiments are used for illustrating the present invention and are not used for limiting the scope of the present invention.

Example 1

The present embodiment provides a skin care composition, which is composed of the following components by weight:

the preparation method comprises the following steps:

(1) adding propylene glycol, dipropylene glycol and phenoxyethanol into an empty container, heating to 60 ℃, and dissolving and dispersing for later use;

(2) sequentially adding hemp seed oil and lecithin into an oil phase tank, heating to 80 ℃, and mixing and stirring uniformly;

(3) adding pure water and hydroxyethyl acrylate/sodium dimethyl taurate acrylate copolymer into a water phase cylinder, heating to 80 ℃, and mixing, stirring and dispersing uniformly;

(4) adding the materials in the water phase cylinder into an emulsifying cylinder, starting a homogenizer and a stirrer, then adding the materials in the oil phase cylinder into the emulsifying cylinder in a homogenizing and stirring state, and uniformly dispersing the materials;

(5) and (3) starting circulating water to cool, when the temperature is reduced to below 45 ℃, sequentially adding the industrial hemp flower and leaf extract, the glycyrrhiza glabra extract, EDTA-2NA, pre-dispersed propylene glycol, dipropylene glycol and phenoxyethanol into an emulsifying cylinder, and stirring and dispersing uniformly to obtain the final product.

Example 2

The present embodiment provides a skin care composition, which is composed of the following components by weight:

the preparation method comprises the following steps:

(1) sequentially adding glycerol, butanediol, methyl hydroxybenzoate, propyl hydroxybenzoate and phenoxyethanol into an empty container, heating to 60 deg.C, dissolving and dispersing;

(2) sequentially adding mineral oil, polydimethylsiloxane, cetostearyl alcohol, caprylic/capric triglyceride, glyceryl stearate and PEG-100 into an oil phase cylinder, heating to 80 ℃, mixing, stirring and dispersing uniformly;

(3) adding pure water and carbomer into a water phase tank, heating to 80 deg.C, mixing, stirring, and dispersing;

(4) adding the materials in the water phase cylinder into an emulsifying cylinder, starting a homogenizer and a stirrer, then adding the materials in the oil phase cylinder into the emulsifying cylinder in a homogenizing and stirring state, and emulsifying and dispersing the materials uniformly;

(5) and (3) starting circulating water to cool, adding the industrial hemp flower and leaf extract, triethanolamine, pre-dispersed glycerol, butanediol, methyl hydroxybenzoate, propyl hydroxybenzoate and phenoxyethanol into an emulsifying tank when the temperature is reduced to be below 45 ℃, and stirring and dispersing uniformly to obtain the final product.

Example 3

The present embodiment provides a skin care composition, which is composed of the following components by weight:

the preparation method comprises the following steps:

(1) sequentially adding hexanediol, phenoxyethanol, chlorphenesin and caprylic hydroximic acid into an empty container, heating to 60 ℃, and dissolving and dispersing for later use;

(2) sequentially adding shea butter, glycerol tri (ethyl hexanoate), isopropyl palmitate, isopropyl myristate, span 60, tween 60, cetearyl glucoside, ceteareth-20 and potassium cetyl phosphate into an oil phase tank, heating to 80 ℃, mixing, stirring and dispersing uniformly for later use;

(3) adding pure water, carbomer and acryloyl dimethyl ammonium taurate/VP copolymer into a water phase cylinder, heating to 80 ℃, and mixing, stirring and dispersing uniformly;

(4) adding the materials in the oil phase cylinder into a main emulsifying cylinder, starting a homogenizer and a stirrer, then adding the materials in the oil phase cylinder into the main emulsifying cylinder in a homogenizing and stirring state, and emulsifying and dispersing the materials uniformly;

(5) and (3) starting circulating water to cool, when the temperature is reduced to below 45 ℃, adding the industrial hemp flower and leaf extract, the glycyrrhiza glabra extract, sodium hydroxide, EDTA-2NA and pre-dispersed hexanediol, phenoxyethanol, chlorphenesin and caprylic hydroximic acid into an emulsifying cylinder, and stirring and dispersing uniformly to obtain the final product.

Example 4

The present embodiment provides a skin care composition, which is composed of the following components by weight:

the preparation method comprises the following steps:

(1) sequentially adding pentanediol, alcohol, ethylhexyl glycerol and p-hydroxyacetophenone into an empty container, heating to 60 ℃, and dissolving and dispersing for later use;

(2) adding isononyl isononanoate, olive oil, jojoba oil, pentaerythritol tetraisostearate, isopropyl palmitate, glyceryl stearate, cetearyl glucoside and polyglycerol-10 myristate into an oil phase cylinder in sequence, heating to 80 ℃, mixing, stirring and dispersing uniformly;

(3) sequentially adding pure water, carbomer, xanthan gum and hydroxyethyl cellulose into a water phase cylinder, heating to 80 ℃, and mixing, stirring and dispersing uniformly;

(4) adding the material in the water phase cylinder into a main emulsifying cylinder, starting a homogenizer and a stirrer, then adding the material in the oil phase cylinder into the main emulsifying cylinder in a homogenizing and stirring state, and uniformly dispersing the material body;

(5) and (3) starting circulating water to cool, adding the hemp flower and leaf extract, the glycyrrhizic acid extract, the potassium hydroxide and the pre-dispersed pentanediol, the alcohol, the ethylhexyl glycerol and the p-hydroxyacetophenone into an emulsifying tank when the temperature is reduced to be below 45 ℃, and stirring and dispersing uniformly to obtain the final product.

Comparative examples 1 to 2

Comparative example 1 is different from example 1 in that the components of the skin care composition do not contain glycyrrhiza glabra extract, and other components and percentage contents and preparation methods are the same as example 1.

Comparative example 2 is different from example 1 in that the components contained in the skin care composition do not contain the industrial hemp flower and leaf extract, and other components and percentage contents and preparation methods are the same as example 1.

Comparative examples 3 to 4

Comparative example 3 is different from example 2 in that the components of the skin care composition do not contain glycyrrhiza glabra extract, and other components and percentage contents and preparation methods are the same as example 2.

Comparative example 4 is different from example 2 in that the components contained in the skin care composition do not contain the industrial hemp flower and leaf extract, and other components and percentage contents and preparation methods are the same as example 2.

Comparative examples 5 to 6

Comparative example 5 is different from example 3 in that the ingredients of the skin care composition do not contain glycyrrhiza glabra extract, and other ingredients and percentage contents and preparation methods are the same as example 3.

Comparative example 6 differs from example 3 in that the ingredients in the skin care composition do not contain the industrial cannabis sativa flower and leaf extract, and the other ingredients and percentage contents and preparation method are the same as example 3.

Comparative examples 7 to 8

Comparative example 7 is different from example 4 in that the ingredients of the skin care composition do not contain glycyrrhiza glabra extract, and other ingredients and percentage contents and preparation methods are the same as example 4.

Comparative example 8 is different from example 4 in that the ingredients of the skin care composition do not contain the industrial cannabis sativa flower and leaf extract, and other ingredients and percentage contents and preparation methods are the same as example 4.

Test example 1

The test examples were conducted to verify the whitening, spot-removing, wrinkle-removing, and anti-inflammatory effects of examples 1 to 4 and comparative examples 1 to 8

After completion of the above example and comparative products, each group of products was distributed to 40 testers for one month (one skin cycle) of trial. The using method comprises the following steps: after cleaning the face in the morning and evening, taking about 1g of sample, uniformly coating the sample on the face, scoring the corresponding efficacy of the product by a tester according to the effect of the product by 10 points, wherein 1 point is the worst, 10 points are the best, the higher the score is, the better the effect is, calculating the average value of each item of data according to the data obtained by the test, and obtaining the following data result.

TABLE 1

Examples	Whitening	Speckle removing method	Wrinkle removing device	Anti-inflammation	Brightening skin color	Even skin tone
							Example 1	9.2	9.0	9.3	8.9	9.5	9.5
Example 2	8.5	8.0	8.8	7.8	8.9	8.9
							Example 3	8.8	8.7	8.4	9.2	8.9	8.7
Example 4	8.3	7.9	8.2	8.4	8.8	8.7
							Comparative example 1	6.4	6.0	6.1	5.0	6.0	6.1
Comparative example 2	5.5	5.9	6.5	5.2	5.3	5.7
							Comparative example 3	4.5	4.7	5.8	5.1	4.8	4.6
Comparative example 4	5.2	5.1	5.9	5.0	4.9	5.0
							Comparative example 5	4.4	4.6	5.5	5.0	4.8	4.5
Comparative example 6	5.7	5.4	4.3	4.8	5.3	5.5
							Comparative example 7	4.9	4.1	5.6	5.3	4.8	4.7
Comparative example 8	5.3	5.7	4.6	4.9	5.0	4.6

As can be seen from the test results in table 1, the skin care compositions of examples 1 to 4 containing the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract exhibited better whitening, spot removing, wrinkle removing, anti-inflammatory, skin tone lightening, and skin tone evening effects, compared to the compositions of comparative examples 1 to 8 in which only one of the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract was added, wherein the skin tone lightening effect was significant. The skin care composition prepared according to the formula in example 1 has the effects of particularly and remarkably whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin and homogenizing skin.

Test example 2

The test example examines the skin care effect of the industrial hemp flower and leaf extract and the glycyrrhiza glabra extract under the condition of different mass proportions.

In this test example, the mass ratios of the industrial cannabis sativa flower and leaf extract and the glycyrrhiza glabra extract in the skin care composition were adjusted to 1:1, 3:1, 5:1, 8:1, 10:1, 1:5, respectively, and the other components of the skin care composition and the preparation method were the same as in example 1. Specifically as shown in table 2.

TABLE 2

Experimental group	Content of industrial hemp flower and leaf extract	Content of Glycyrrhiza glabra extract	Mass ratio of
				Group 1	0.05％	0.05％	1:1
Group 2	0.24％	0.08％	3:1
				Group 3	0.4％	0.08％	5:1
Group 4	0.48％	0.06％	8:1
				Group 5	0.4％	0.04％	10:1
Group 6	0.02％	0.1％	1:5

After completion of the skin care composition products in the above groups, the products of each group were distributed to 20 testers for one month of trial (one skin cycle). The using method comprises the following steps: after cleaning the face in the morning and evening, taking about 1g of sample, uniformly coating the sample on the face, scoring the corresponding efficacy of the product by a tester according to the effect of the product by 10 points, wherein 1 point is the worst, 10 points are the best, the higher the score is, the better the effect is, calculating the average value of each item of data according to the data obtained by the test, and obtaining the following data result as shown in Table 3.

TABLE 3

Experimental group	Whitening	Speckle removing method	Wrinkle removing device	Anti-inflammation	Brightening skin color	Even skin tone
							Group 1	6.2	6.0	6.7	6.5	7.1	6.9
Group 2	7.5	7.4	7.9	7.3	7.9	7.6
							Group 3	9.3	9.1	9.2	8.9	9.5	9.4
Group 4	7.2	7.5	7.8	7.1	8.0	7.8
							Group 5	6.5	6.1	6.4	6.3	6.8	6.7
Group 6	6.0	5.8	6.1	6.0	5.7	5.9

As shown in the results in the above table, in groups 1 to 6, when the mass ratio of the industrial cannabis sativa flower and leaf extract to the glycyrrhiza glabra extract is 5:1 (group 3), the skin care composition has better effects of whitening, removing freckles, removing wrinkles, diminishing inflammation, brightening skin color and homogenizing skin color, wherein the effect of brightening skin color is more obvious. In group 6, when the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 1:5, the effects are poor.

Although the present invention has been described with reference to a preferred embodiment, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. The skin care composition is characterized by comprising an industrial hemp flower and leaf extract and a glycyrrhiza glabra extract, wherein the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 1.5-16: 1.

2. the skin care composition according to claim 1, wherein the mass ratio of the industrial cannabis sativa flower and leaf extract to the glycyrrhiza glabra extract is 3-8: 1;

more preferably, the mass ratio of the industrial hemp flower and leaf extract to the glycyrrhiza glabra extract is 5: 1.

3. the skin care composition according to claim 1 or 2, wherein the skin care composition comprises the following components in percentage by weight:

4. a skin care composition according to any one of claims 1 to 3 wherein the cannabidiol content of the industrial cannabis sativa flower leaf extract is greater than 10% and the tetrahydrocannabinol content is less than 0.3%;

preferably, the content of cannabidiol in the industrial cannabis sativa flower and leaf extract is more than 40%.

5. A skin care composition according to any one of claims 1-4 wherein said Glycyrrhiza glabra extract comprises glycyrrhizic acid in an amount of greater than 10% and glabridin in an amount of greater than 30%;

preferably, the content of glycyrrhizic acid is more than 25%, and the content of glabridin is more than 40%.

6. A skin care composition according to claim 3 wherein said emollient is selected from at least one of hemp seed oil, mineral oil, dimethicone, cetearyl oil, shea butter, caprylic/capric triglyceride (ethylhexanoic acid), isopropyl palmitate, isopropyl myristate, dioctyl carbonate, isononyl isononanoate, olive oil, jojoba oil, pentaerythritol tetrastearate.

7. A skin care composition according to claim 3 wherein said thickening agent is selected from at least one of carbomer, collagen, hydroxyethyl cellulose, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, ammonium dimethyltaurate acrylate/VP copolymer.

8. A skin care composition according to claim 3 wherein said emulsifier is selected from at least one of glyceryl stearate, PEG-100 stearate, cetearyl glucoside, ceteareth-20, lecithin, tween 20, tween 60, span 60, polyglyceryl-10 myristate, potassium cetyl phosphate.

9. A skin care composition according to claim 3 wherein said preservative is selected from at least one of methylparaben, propylparaben, phenoxyethanol, chlorphenesin, p-hydroxyacetophenone, caprylhydroxamic acid;

preferably, the polyhydric alcohol is at least one selected from glycerol, propylene glycol, dipropylene glycol, alcohol, butylene glycol, pentanediol, hexanediol, octaethylene glycol, and ethylhexylglycerin;

preferably, the additive is at least one selected from EDTA-2NA, sodium hydroxide, potassium hydroxide and triethanolamine.

10. A method of preparing a skin care composition according to any one of claims 3 to 9 comprising the steps of:

(1) adding polyalcohol and antiseptic into a container, heating, dissolving and dispersing for use;

(2) adding the emollient and the emulsifier into the oil phase tank, heating, and uniformly stirring and dispersing for later use;

(3) adding pure water and a thickening agent into a water phase tank, heating, mixing, stirring and dispersing uniformly;

(4) adding the materials in the water phase tank into an emulsifying tank, starting a homogenizer and a stirrer, then adding the materials in the oil phase tank into the emulsifying tank in a homogenizing and stirring state, cooling after uniform emulsification and dispersion, adding the industrial hemp flower and leaf extract, the glycyrrhiza glabra extract, the additive and the polyol and the preservative which are dissolved and dispersed in advance for standby in the step (1) into the emulsifying tank when the temperature is reduced to be below 45 ℃, and uniformly stirring and dispersing to obtain the skin care composition.